South Carolina
South Carolina was a region located on the Atlantic coast of the North American continent of Earth. This was a state in the United States of America. The bordering states were Georgia and North Carolina. It was one of the original thirteen states of the United States, and was mentioned in Article I of the United States Constitution. (; ; )

In an alternate timeline in which Nazi Germany had invaded the United States, as of 1944 South Carolina was controlled by German forces. A section of the state was a border area between the German and American forces. ()

In 2349, Harry Kim was born in this state. ()

Omega IV 
On the planet Omega IV, this was one of the states of a parallel United States. It was mentioned in Article I of their Constitution. ()

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fr:Caroline du Sud
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Earth subnational entities