LSD
D-lysergic acid diethylamide (C20H25ON3), commonly called LSD, was a powerful psychotropic drug that was used for medical, spiritual, and recreational purposes on Earth. 

While visiting Earth in 1986, Admiral James T. Kirk attempted to explain Spock's erratic behavior to Gillian Taylor by saying that he believed his "harmless" friend had used too much LSD, mistakenly referring to it as "LDS", during the 1960s while "he was part of the Free Speech Movement at Berkeley", California. Taylor noted his mistake before agreeing to give them a lift. ()

In 2381, Ensign Sam Rutherford mistakenly referred to SMD as "LSD" while he was being chased down the corridor by Ensign D'Vana Tendi. ()

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Drugs
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Recreation