Mange
Mange was a type of skin disease caused by parasitic mites.

In November 2154, Hoshi Sato described Porthos to Jonathan Archer as mangy as part of a hostile discourse in preparation for the arrival of a Tellarite delegation. ()

In 2375, General Martok reminisced with Benjamin Sisko about a pet targ he once owned, which he described as a "filthy, mangy beast." ()

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Medical conditions