Vanguard characters
This is a list of characters who have appeared in Star Trek: Vanguard.

Characters
Diego Reyes  Commodore, commanding officer of Starbase 47.

Jon Cooper  Commander, first officer of Starbase 47.

T'Prynn  Vulcan lieutenant commander, Starfleet Intelligence officer of Starbase 47, living in self-imposed exile from Vulcan due to her being a val'reth- she holds the katra of her former fiancé, whom she killed in the heat of pon farr, against her will; in a relationship with Anna Sandesjo/Lurqal. T'Prynn also appears in the Pocket DS9 Mission Gamma novel Lesser Evil.

Jetanian  Chelon ambassador from the Federation. His senior attaché is Anna Sandesjo, who had a relationship with Lieutenant Commander T'Prynn.

Ming Xiong  Starfleet sciences division lieutenant assigned as archaeology and anthropology officer.

Ezekiel Fisher  Chief medical officer.

Rana Desai  Starfleet captain assigned as JAG officer, and Commodore Reyes' girlfriend.

Tim Pennington  Journalist, working for the Federation News Service. The Pennington School of journalism, later mentioned on , was named in his honor.

Cervantes Quinn  Trader.

Anna Sandesjo (Lurqal)  Diplomatic attaché with a secret; also engaged in a relationship with T'Prynn despite the dishonor of such a relationship in Klingon society.

Ganz  Orion merchant.