James Moriarty
For the sentient hologram based on this character, see James Moriarty (hologram).
Professor James Moriarty was a fictional character from the 19th century Sherlock Holmes novels by Sir Arthur Conan Doyle. He was an adversary to Sherlock Holmes, a man with knowledge equal to that of Holmes.  Appearing in two Holmes stories, Moriarty was defeated by Sherlock Holmes at Reichenbach Falls, but only at the cost of Holmes' own life.

Katherine Pulaski read Sherlock Holmes novels and short stories in her youth and was always frightened by the despicable Moriarty.  A love interest of Professor Moriarty was the Countess Regina Barthalomew. ()  

A hologram based on Moriarty was created on board the  in 2365. The hologram grew far beyond the parameters of the Moriarty character when Geordi La Forge misspoke and requested that the computer create an adversary that could defeat Data, rather than Holmes as portrayed by Data. To do so, the computer had to program the Moriarty hologram with Data's considerable knowledge; as a side effect, the Moriarty hologram became self-aware.   In 2369, when the holographic Moriarty appeared to gain the ability to exit the holodeck, Captain Picard warned him that the criminal behavior shown in the novels and short stories would not be acceptable in the 24th century. The holographic Moriarty assured him that he was not the same as the fictional character from the "scribblings of an Englishman dead for four centuries." ()

External links 
 
 
 James Moriarty at the Sherlock Holmes wiki

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Fictional characters
Professors