Basidiosac rupture
A basidiosac rupture was an issue that might occur while using spore drive. 

After the crew of the  was lost during spore drive maneuvres in 2256, a team sent to determine the cause saw spiral etchings on its hull that provided evidence of catastrophic basidiosac rupture. Later, helical trauma correlating to these markings were found in one of the dead crew. ()

Propulsion technology