Unnamed Alpha and Beta Quadrant star systems
The following are unnamed Alpha and Beta Quadrant star systems.

2466 PM solar system 
This uncharted solar system, located at 2466 PM, contained a planet where the Metrons forced Kirk to fight a Gorn captain. ()

Akaali system 
Located seventy-eight light years from Earth, this inhabited system was in the general vicinity of a cluster of three neutron stars and a J'ral class supernova remnant. The Akaali homeworld was located in this system. In 2151,  defeated a Malurian vesssel in this system. ()

Amargosa system 
This system accompanied the star Amargosa and included the Amargosa observatory, a space-based Federation facility. In 2371 the facility was attacked by Romulans, sparking concern of a new Romulan threat in the sector. At the time the Enterprise detected no ships in the system, though a cloaked Klingon ship was present. Shortly thereafter, a trilithium weapon launched into Amargosa by the rogue scientist Tolian Soran triggered the star to collapse, producing a level twelve shock wave expected to destroy everything in the system. ()

Argolis Cluster system 
This system within the Argolis Cluster was charted by the  in 2368. During the mission, the Enterprise picked up a transmission from a crashed Borg scout ship on a small moon orbiting the fourth planet. The Federation starship rescued the drone Hugh from the wreckage. ()

Arkaria system 
This system contained the inhabited planet Arkaria. 

In her plans to steal the trilithium resin from the  in 2369, Kelsey, the leader of a group of mercenaries, had arranged a get-away ship which would get her people and the trilithium resin out of the system. Some time later, as the ship attempted to leave the system, it was destroyed by the triithium resin which had become destabilized. ()

Arret system 
This Alpha Quadrant system was located hundreds of light years past the limits of Federation exploration in 2268. That same year, the  was directed to the planet Arret in this system by the thought energy of Sargon. ()

Arret (negative) system 
This reverse negative antimatter universe star system was in the same galactic position as the Sol system in the forward positive matter universe. The inhabited planet  was located in this system. In the mid-23rd century, Karl Four pointed out the location of his home system on a galactic map to Robert April, James T. Kirk, and Spock. ()

Ba'ku system 
This Alpha Quadrant system was located in the Briar Patch, a region of space in Sector 441. The system had one class M planet –  – which was colonized by the Ba'ku. According to Ru'afo, the injector assembly, if fired at the planet Ba'ku, would leave all life in the system dead or dying in six hours. This system was located in Federation space. ()

Ba'ku home system 
This system was the home system of a group of settlers who founded a colony on the Ba'ku planet in 2066. This system's civilization had technology which could destroy all life and the settlers feared their species was on the verge of self-annihilation. ()

Badlands solar system 
This planetary solar system was located in the Badlands. The system had at least one star.

In 2371, a Starfleet runabout piloted by Kira Nerys pursued a Maquis courier ship into this system. The Maquis ship crash landed on a moon of a gas giant in this system. ()

Barzan system  

This Alpha Quadrant system was home to the Barzan species, who inhabited the system's second planet,  Barzan II. The system was also home to multiple moons, of which  and  were said to be the "most beautiful". ()

For a time, the system was a fixed endpoint for the Barzan wormhole until 2373, when it was accidentally destabilized by Dr. Arridor and . (; ).

Battle Group Omega rendezvous 

This system was located in Sector 1045. In 2379, Star Fleet Battle Group Omega planned to rendezvous in this system to combat the Scimitar, though ultimately the Scimitar was destroyed by the  in the Bassen Rift. ()

Binary system 

This binary star system was explored by Enterprise NX-01 in September 2152. Captain Jonathan Archer and Commander Tucker prepared  to visit the surface of an uninhabited planet but were forced to leave when a neutronic wavefront approached. ()

Binary system (2368) 
This binary system was the "most unusual thing" in a routine mapping of a sector by the  in 2368. ()

Binary system at edge of Federation space 
Just before the  of 2256, this system was at the most remote borders of Federation space, though still part of its territory. According to the Klingon Empire however, it was too close to Klingon territory. Around its two suns, an accretion disk containing ice, dust, and gasses collided to form planets future generations would call home. It was described as "beautiful". It was located six light years away from Gamma Hydra and three from Eagle-12, which were both Federation positions.

However, the disk also contained high levels of radiation, brisk temperatures of −260 degrees Celsius, and the binaries were kicking off serious QE's up and down the spectrum.

It hosted an Starfleet interstellar relay, which in 2256 was found destroyed. The  was ordered to investigate, and found the Beacon of Kahless at the heart of a Klingon trap. The resulting battle, known as the Battle of the Binary Stars, set off the Federation-Klingon War of 2256. ()

Binary system inside a Tyken's Rift 
This uncharted star system was a binary star system that was located within a Tyken's Rift. 

In 2367, a mysterious alien became trapped in the rift and with the help of the  managed to escaped. The stars of this system were described by Deanna Troi as being "twins". ()

Bre'el IV system 
This system contained the inhabited planet Bre'el IV. In 2366, a large celestial object passed at near right angles to the  of this system, resulting in Bre'el IV's moon entering into a deteriorating orbit. The moon was restored to its place by Q. ()

Bryma system 
This system contained the inhabited Cardassian planet Bryma and its colony, the Bryma Colony. In the early 2370s, this system was in the Demilitarized Zone.

In 2370, before the Maquiss failed attack on Bryma, Federation runabouts from Deep Space 9 mined the system's Oort cloud with sensor probes. These well-hidden probes detected the Maquis ships as they entered the system and gave the runabouts an advantage for the upcoming battle. ()

Cold Station 12 system 

This system contained a large asteroid field. One asteroid was the location of Cold Station 12, a facility operated by the Interspecies Medical Exchange. During the Augment Crisis in 2154, this asteroid field was the site of a battle between  and a  hijacked by Arik Soong's Augments. ()

Cytherian homeworld system 

This system, identified by Data as a planetary cluster, was located 30,000 light years from the Argus Array. Located near the galactic center, the system contained the homeworld of the Cytherians. In 2367, this system was visited by the . ()

Delta Theta III system 
This star system contained the inhabited planet Delta Theta III, orbiting the system's sole star.

In the 23rd century, this system was explored by a scouting mission, which discovered possible evidence of the native civilization on Delta Theta III. First contact with the natives was made by a contact team from the  in 2270. After learning that the world was protected by an alien intelligence, the planet was quarantined. ()

Ekos and Zeon system 
This star system was home to two planets inhabited by humanoids. Ekos, home of the Ekosians, occupied an orbit inward from its' sister planet, , home to the Zeons. 

Following the elimination of the Nazi regime on Ekos, along with the predicted cooperation with their Zeon neighbors, Spock recommended that "With the union of [these] two cultures, this system would make a fine addition to the Federation." ()

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Epsilon 119 system 
This system contained the star Epsilon 119. 

In 2370, Professor Gideon Seyetik, a famed Federation terraformer, believed that by re-igniting Epsilon 119 that he would be "brining new life" to this system. ()

Excalbia's solar system  
This solar system contained the planet Excalbia. When the crew of the  was about to bear witness to the conflict the Excalbians set up to demonstrate the differences between "good" and "evil", their representative Yarnek announced: "We welcome the vessel Enterprise to our solar system and to our spectacle." ()

Exo III system 
Exo III was located in a system of which the sun had been fading for half a million years as of the 23rd century. ()

Fifty systems 
These fifty systems had planets which were in the same predicament as  in 3189. 

The pre-warp civilizations on these planets were contacted by the Emerald Chain. The Chain saw something they wanted and, in exchange, they would help them in solving problems. This aid came with strings attached, keeping the planets indebted to the Chain. Many, if not all, of them were bound to collapse. 

These systems were being tracked by the Federation. ()

Gosis' species star system 
Gosis' species system was a system with only one habitable planet. 

When Enterprise NX-01 visited his planet in 2152, Temec reasoned that the Humans must have come from an alien system, since "none of the other planets are capable of supporting life." ()

Hekaras II system 
This system, located near the Hekaras Corridor in the Hekaras sector, was home to the inhabited planet Hekaras II. 

In 2370, during its search for the missing medical transport Fleming, the  asked the Hekaran government if the ship had recently passed through their system. The answer was negative with the government adding that the only ship to pass through their system in the past week being a Ferengi trader. ()

Iconian influenced systems 
Three Beta Quadrant systems, located in or near the Romulan Neutral Zone and in the same sector, demonstrated similar cultural traits, indicating they were influenced by the Iconians. ()

J'naii system 
This inhabited star system was where , the homeworld of the J'naii, was located. It also had a null space pocket, a fact which was only discovered in 2368. ()

Kavis Alpha sector binary system 
This unnamed binary system consisted of a neutron star, a red giant, and Kavis Alpha IV. The neutron star went through a cycle of sucking matter from the nearby red giant, then explosively expelling the matter into space, every 196 years. 

In 2366, Doctor Paul Stubbs recorded this historic event, from the Enterprise-D, using a customized probe known as "The Egg." ()

Lazarus' planet system 
This star system was visited by the  in 2267. As the starship was completing its survey of an iron-silica planet, the whole system experienced a disruption of its magnetic field. ()

Malcor III system 
This star system, containing the inhabited planet Malcor III, was a single star system with six planets. The nearest system was the Garth system and Earth was over 2,000 light years away. ()

Marva IV's system 
This star system contained the inhabited planet Marva IV. It was located in the Demilitarized Zone and near to the Badlands. 

In 2373, after the  traced Michael Eddingtons transporter signal to a Maquis raider, Kira Nerys reported to Benjamin Sisko that the ship was breaking orbit over Marva IV and heading out of the system. ()

Mixtus system 

This unnamed system contained the inhabited planets Mixtus II and Mixtus III, and was home to the Mixtus inhabitants. ()

New Berlin Colony system 
This system was administered by the Federation New Berlin Colony. It was in the same sector as the Ohniaka system and the MS system.

In 2369, the colony sent out a distress call fearing a Borg incursion, while all that had happened was that a Ferengi trading ship had entered their system. ()

Quantum fissure system 
This system was, in 2370, the site of a quantum fissure event. 

In one of the quantum realities experienced by Worf during this event, Data scanned this system for temporal anomalies in this system with a negative result. ()

Panora's system 
This system contained the planet Panora, which was, in the late 24th century, home to a Cardassian colony. Located in the Demilitarized Zone from 2370 to 73, this system had constant ion storms, which an attacker could take advantage of for a surprise attack. ()

Paxan system 
This unnamed system was located in a pocket of the Ngame Nebula. It contained a T-Tauri type star and a single class M planet which was the Paxan homeworld. The Enterprise-D went through this system to investigate it and, running into the Paxans, agreed to erase knowledge of the area from their computer and themselves. Believing they passed through an unstable wormhole, they decided to continue on and sent Starfleet a hazard advisory about the wormhole. ()

Pyris VII system 
This unnamed system in the Alpha Quadrant contained the plant Pyris VII. Before the  visited Pyris VII in 2267, several mapping expeditions had been sent by the Federation to this system. These expeditions did not find lifeforms on the seventh planet. ()

Rock creature planet system 
This uncharted system was visited by the  in 2269. It was a binary star system with a lone Class M planet, an unique find. ()

Romulan-held system 
This system, uncharted according to Starfleet, had several planets including one that was Minshara class. The system turned out to be claimed and defended by the Romulan Star Empire, which did not tolerate others entering it. ()

Romulan Neutral Zone solar systems 
In 2365, the  eluded a Romulan cruiser by playing hide and seek in these solar systems located in the Romulan Neutral Zone. ()

Sector 1156 system 

This system in Sector 1156 consisted of a primary and four planets. 

In 2370, the  discovered the D'Arsay archive in this system. ()

Seven systems 
In these seven systems, Plix Tixiplik was wanted for illegal weapon sales. ()

Starbase 234 system 
This inhabited system, located in the Beta Quadrant, had at least one planet, which was home to Starbase 234. 

In 2368, Picard's blockade fleet assembled in this system. Later, after clearing the system, the fleet went to warp. ()

Star systems visited by Ullians 
These seven star systems, home to ten planets, were visited by the Ullian telepathic historians in the 2360s. They were collecting a library of memories from the inhabitants. ()

Suliban hiding system 

This binary star system was located two and a half light years from Paraagan II. It contained at least two planets, and at least two moons. 

In 2152, a Suliban stealth cruiser hid on the inner moon of the second planet orbiting the smaller star in the system. Enterprise NX-01 disabled the Suliban cruiser in this system and stole its data disks to prove it wasn't responsible for the destruction of the Paraagan mining colony. ()

Systems attacked by Borg 
These three systems were in sensor range of the  after the ship had exited a transwarp conduit in 2369. The starship scanned the systems, discovering the evidence of at least two advanced civilizations in those systems. However, the lack of life signs and indications of plasma weapons being fire suggested to the crew that the Borg had been active in those systems. ()

System with Kuiper belt 

In 2375, Odo and a defective Weyoun clone managed to evade capture by Jem'Hadar by hiding in this system containing a Kuiper belt. ()

T-Tauri systems near wormholes 
These thirty-nine T-Tauri systems were located near small and unstable wormholes. The first of these wormholes was mapped in the 23rd century. ()

Taurus II system 
This inhabited planetary system was located in the Murasaki 312 quasar, in the Alpha Quadrant. It was one of four systems in the same sector as the quasar, and was three light days away from Makus III.

It had one planet capable of supporting life, known as Taurus II. This system was unexplored by the Federation as of 2267, when the  rescued the crew of one of its shuttles. ()

Terellian freighter-crash planet system 
This system was a single star system with a sole Class M planet. It was in the same sector as the Iyaaran homeworld. ()

Terra Nova system 

A display graphic demonstrated Terra Nova to be part of a solar system containing several other planets. ()

Tholian system 
This system was home to the xenophobic Tholians. When Enterprise NX-01 encountered a Tholian vessel in 2152, T'Pol remarked that it was unusual for Tholians to travel that far from their system. ()

Trinary star system 

This unidentified trinary star system was encountered by the  in 2152. It contained a black hole. ()

Ventax II system 
This system was the home system for Ventax II. 

In 2367, the  conducted a high-resolution scan of this system as they searched for Ardra's starship. ()

War games simulation system 
In a holographically-simulated tactical scenario played out on  in 2371, a red giant system 3.7 light years away, with eight planets, none of them M class, played a minor role. ()

Xindi-Arboreal colony system  
This system, which contained at least one planet and one moon was visited by  in 2153. After Enterprise entered the system, it positioned itself behind the far side of the system's moon in order to keep the out of view of the Xindi-Arboreal colony they were observing. ()

Xindus solar system 

This system was located in the Delphic Expanse. It contained a yellow-orange star and a single planet, Xindus, which was destroyed in the 2030s and left behind an asteroid field nearly eighty million kilometers long. The system was abandoned by the time  visited it in 2153. ()

Yonada system 
In 2268, the  discovered the asteroid ship Yonada in this solar system. ()

Yonada Prime system 
The Yonada Prime system was a planetary system in Sector 2158, a region of space in the Beta Quadrant. The system consisted of a primary and three planets, including Yonada Prime. It was located near the Romulan Neutral Zone. ()

Zalkonian star system 
The Zalkonian homeworld Zalkon was located in this star system. This system was within Sector 9569.

In 2366, the  was on a course to this system, ferrying the Zalkonian "John Doe" to his home, when they were intercepted by a Zalkonian warship commanded by Sunad. ()

Zeta Gelis star cluster star system 
This unknown star system in the Zeta Gelis star cluster was charted by the  in 2366. During its mission, the Enterprise-D discovered a Zalkonian escape pod on the surface of one of the system's planets. ()