16th century
The 16th century was defined by the calendar of Earth as occurring from the year 1501 through the year 1600.

Events
 Bajoran explorers build solar-sail spacecraft to explore their star system. ()

 The T-Rogorans conquer the Skrreea. They kill most of the Skrreean leaders, and force the rest of the population to work as laborers and servants. ()
 According to Q, in this century, Humans are fighting each other over "tribal god images". () 

 Autopsy reports relevant to duels over a woman going as far back as this year are later included in The Doctor's database. ()

 An attempted Spanish invasion of England is thwarted. () 

 In western Europe, early experiments with the optical microscope are made. Sketchbooks and other forms of art of the time record early observations of a more or less scientific nature, as seen during Captain Janeway's Leonardo da Vinci holodeck program. ()

Appendices

Background information 
 T-Rogorans became warp-capable in 1570 AD. (Star Trek: Star Charts)
 The following events are from the fourth edition of the Star Trek Encyclopedia  (vol. 1, pp. 146, 154, 176, 215, & 324 & vol. 2, pp. 41, 269):
 The Scottish Highlanders use the claymore for the first time.  
 Don Juan first appears in Earth literature. 
 1502 - The Leonardo da Vinci's workshop is set around this year.
 1506 - Christopher Columbus dies.
 1519 - Leonardo da Vinci "dies".
 1564 - William Shakespeare is born.
 1595 - A Midsummer Night's Dream is written by William Shakespeare.
 circa 1599 - Macbeth is written by William Shakespeare.
 circa 1600 - Hamlet is written by William Shakespeare.

External links 
 
 

nl:16e eeuw