Starbase 157
Starbase 157 was a Federation starbase administrated by Starfleet. This starbase was located in the Beta Quadrant. 

The starbase was operational by 2256 at the latest. ()

In that year, this starbase's location was labeled on the star chart "Alpha/Beta Quadrant Overview" in the ready room aboard the . ()

In 2257, during the first , this starbase was occupied by the Klingons. () 

In 2258, the starbase's location was labeled on a star chart seen on the main viewscreen of the . ()

In 2366, this base picked up the final distress call from the freighter Lalo. The Lalo reported encountering an unknown cube-shaped vessel, which was later encountered and identified by the  as a Borg ship. ()

In 2399, this starbase's location in neutral space was labeled on a Federation star chart that was in Fleet Admiral Kirsten Clancy's office at Starfleet Headquarters. ()

Appendices

Background information 
According to StarTrek.com, this starbase was located close to the Mempa sector.

Apocrypha 
According to the Star Trek: Destiny  Gods of Night, Starbase 157 was destroyed by the Borg in 2381.

Taking place in 2409, the computer game Star Trek Online depicted Starbase 157 as being located near the Klingon border and hosting a large shipyard facility.

External link 
 

bg:Звездна база 157
de:Sternenbasis 157
fr:Base stellaire 157
ja:第157宇宙基地
nl:Sterrenbasis 157
0157, Starbase