No, in that case, the sticker can't be removed and you won't be able to apply for a full refund.
What is needed to apply for the 2-year refund?
The 2-year registration fee refund can only be applied if the registration was never used and it hasn't been more than 60 days from the date the registration was issued.
So if I applied for a registration but never used the registration sticker, can I get a 2-year refund?