Background
DISEASE
Electronic nicotine delivery systems or vaping (referred to hereafter as “e-cigarettes”) are battery-powered devices that simulate the experience of smoking by heating a liquid solution into an aerosol, which is then inhaled by the user [According to a survey conducted in the United States (US) by the Centers for Disease Control and Prevention in 2020, among adult e-cigarette users, 34.7% reported using e-cigarettes to quit smoking cigarettes, and 29.8% reported using e-cigarettes to reduce their cigarette smoking [In-person traditional behavioral interventions such as counseling, support groups, and pharmacotherapy (eg, nicotine replacement therapy or medications to aid cessation) have been used to aid in cigarette smoking cessation [Among smoking cessation apps, iCanQuit is the only app that has demonstrated efficacy for cigarette smoking cessation in a full-scale RCT with long-term follow-up [The results from the iCanQuit parent trial showed (1) potential for high reach nationwide, (2) higher efficacy for cigarette smoking cessation of iCanQuit relative to QuitGuide (12-month quit smoking rates: 28% in iCanQuit vs 21% in QuitGuide; 