Side effects
Headache, nausea, vomiting
ADVERSE EVENTS
No severe adverse events were observed. Three participants (27%) reported a clinically significant measure of nausea during the DH arm compared with none in the SH arm. Headache was reported by four (36%) in both the SH and the DH arm. Stomach-ache was reported by two (18%) in the DH arm and one (9%) in the SH arm. None experienced vomiting. All reported side effects were mild in severity and, besides from hypoglycemic- and hyperglycemic episodes, required no intervention.