Criteria for discontinuing or modifying allocated interventions {11b}
MINOR
As this pragmatic trial was embedded into routine donation services, the study has been open to the following minor amendments. First, if a participant has not wished to receive the trial’s interventions, they have been able to receive NHSBT’s standard interventions (e.g. water loading rather than the isotonic drink evaluated in the trial). Second, the trial has been conducted during the COVID-19 pandemic, meaning that during the study NHSBT has routinely implemented service-wide revisions with the aim of enhancing donor and staff safety at donation sessions, including limiting the number of donors per session and removing hot drinks previously offered after donations.