Follow-up
After study intervention, patients will be followed up after one day, one week, and at 3, 6, 9, 12, 18 and 24 months or if any symptoms occur necessitating work-up. Study assessments at the different follow-up timepoints are shown in Table 
Planned study assessments during follow-upD = day; M = month; O = optional; PROMS = patient reported outcome measures; QoL = quality of life; X = mandatory; W = week. PROMS include EQ5D, SF-36, Treatment decision regret score