Patient selection
fracture, opioid dependence, end-stage osteoarthritis, cardiovascular and cerebrovascular embolism
PULMONARY EMBOLISM, RENAL FAILURE, DISEASES, DEEP VEIN THROMBOSIS
Patient inclusion criteria: patients underwent THA in our hospital for end-stage osteoarthritis of the hip from November 2021 to October 2022. Exclusion criteria: (1) history of diseases that cause abnormal inflammatory markers; (2) history of hip fracture; (3) history of renal failure; (4) history of cardiovascular and cerebrovascular embolism in recent 1 year; (5) history of stent implantation in recent 1 year; (6) history of deep vein thrombosis or pulmonary embolism; (7) pregnant or nursing women; (8) poor compliance; (9) refuse to participate. Withdrawal criteria: (1) previous history of opioid dependence; (2) violation of treatment principles and poor compliance; (3) failure to cooperate with doctors during medication treatment and loss of follow-up; (4) patients and their families called for the trial to be stopped.