2.5. Determination of the anesthetic effect
SE, allergic reaction, pain
MUSCLE RELAXATION, ALLERGIC REACTION
The patient’s tolerance to the anesthesia regimen and allergic reaction were evaluated by comparing the hemodynamic status.When the values of SE and RE were both >65 or the difference was >10, it reflected the recovery of pain or muscle relaxation, and anesthesia was considered insufficient.An amplitude of SPI change >10 or SPI value >50 was considered to indicate insufficient analgesia.When one or more of these conditions were met, propofol (1 mg/kg) was rapidly pumped and the patient was observed for 5 minutes. If it was ineffective, diltiazem (Beijing SHKB Pharmaceutical Co. Ltd., Beijing, China; approval number: approved Chinese medicine H20031228; specification:10 mg) 0.2 mg/kg total dose ≤ 10 mg was given intravenously and the patient was observed for 5 minutes. The failure of OFA was defined as ineffective sequential use of the 2 treatments, and remifentanil 2 to 4 ng/mL was injected timely as a rescue.