Background
sepsis, gastrointestinal diseases, SIRS, organ failure
ACUTE PANCREATITIS, GASTROINTESTINAL DISEASES, DISEASE OF THE PANCREAS, ACUTE PANCREATITIS, SEPSIS
Acute pancreatitis (AP), an inflammatory disease of the pancreas, is the leading cause of hospital admissions for gastrointestinal diseases worldwide [Several scoring systems have been identified to predict the severity and prognosis of AP and sepsis, including the SIRS score, bedside index for severity in acute pancreatitis (BISAP) score, sequential organ failure assessment (SOFA) score, quick-SOFA (qSOFA), simplified acute physiology score II (SAPS II) [Herein, this study aimed to (1) construct predictive models for the risk of sepsis in patients with AP using machine learning methods and validate the predictive performances; (2) select the optimal machine learning model and compare it with the LR model and scoring systems. This study may help to identify the risk of sepsis in patients with AP at an early stage and assist in the clinical treatment of AP and the prevention of sepsis.