Enrichment of beneficial bacteria associated with the clinical remission after FMT accompanied the decrease in levels of opportunistic pathogens.
UC
REMISSION
UC patients who achieved clinical remission exhibited efficient and durable changes in their gut microbiota after FMT. Based on 16S V3-V4 sequencing, gut bacterial richness was increased in the clinical remission (Rm) group and was comparable to that of donors during the follow-up visits after FMT. In contrast, the richness indices at week 4 and week 12 after FMT were significantly (Changes in gut bacterial communities associated with Rm and NRm after FMT. (A) α diversity of Rm, NRm, and donor samples, estimated by richness (observed OTUs) and Shannon and Pielou’s evenness. The dashed line indicated significant (To identify the taxa associated with clinical remission, the differences in genera in the Rm or NRm groups were evaluated between each time point after FMT, and the baseline values were analyzed by the paired rank sum test. 