Author contributions
JJ
JJ, RM, JB, MKH contributed to the conception or design of the work. RM and YL contributed to the acquisition, analysis, or interpretation of data for the work. RM and JJ drafted the manuscript. MKH, YY, NS, JB, CAP, MJ and HJLH critically revised the manuscript. All gave final approval and agree to be accountable for all aspects of work ensuring integrity and accuracy.