NanoString Analysis
tumor
TUMOR, COLD
For murine EMT6 pharmacodynamic studies, tumor tissue was harvested from mice 48 hours after second and third dose of indicated mAbs and placed in 50 mL conical tubes containing cold serum-free RPMI1640 (Gibco) and kept on ice until dissociation. Following mechanical dissociation (gentleMACSSimilar analyses were conducted on isolated bulk (CD3