Strengths and Limitations
CMD
Our study’s strengths include a large sample size, long follow-up, and pragmatic study design resembling clinical practice conditions in rural Zimbabwe. Further strengths of our study include using electronic pill bottles for adherence monitoring and using a locally developed tool to measure CMD symptoms.Our study has several limitations. First, the mental health screening tools used in this study have been validated in Harare but not in the rural study setting, where our study took place.