Metabolic reprogramming related differentially expressed metabolites participated in the occurrence of sepsis
sepsis
SEPSIS
The ionization source of Orbitrap is electrospray ionization, including positive and negative ion modes (POS and NEG, respectively), which can increase the metabolite coverage and improve the detection effect. Subsequent data analysis involved separate analyses of the two groups. Principal component analysis (PCA) revealed significant differences in metabolites between sepsis patients (SP) and healthy controls (HC) (Fig. Identification of differentially expressed metabolites (DEMs) between control and sepsis. Figure Correlation and function enrichment analysis of DEMs. Pathway analysis of DEMs in (