2.7. Statistical Analysis
HIV drug, death, viral suppression
REGRESSION
First, we describe the proportion of participants from either group who underwent DRT as part of the study intervention or at the study end, per protocol, and the proportion with DR mutations detected by HIV drug classes, e.g., NRTIs, NNRTIs, and PIs. All DRTs for each participant were reviewed, but only one DRT result contributed to the data analysis. For a report of DRMs by drug class, the DRT with the highest number of mutations was used. We report on the prevalence of HIV DR by ARV medication using WHO’s definition of a penalty score of ≥15 using the Standford HIVdb algorithm [Second, to evaluate which CHIV were most likely to have clinically relevant DR, we used logistic regression models to identify factors associated with clinically significant DR. Variables with Third, to explore any potential impact of DRT on clinical outcomes, we report descriptive statistics for outcomes including viral suppression (VS), loss to follow up, and death by study group among those with DRT results, categorized by whether an ART regimen change occurred or not.