Acknowledgements
We thank all the patients who participated in this trial and their families. We thank Mian Wei (Medical Manager, Jiangsu Hengrui Pharmaceuticals Co., Ltd) for her input in data interpretation, Yitao Wang (Clinical Statistics Manager, Jiangsu Hengrui Pharmaceuticals Co., Ltd) for statistical support, and Fangzhou Xia (Medical Writer, Jiangsu Hengrui Pharmaceuticals Co., Ltd) for medical writing assistance.