Sedation-related adverse events
respiratory adverse, postoperative nausea and vomiting, hypoxemia, hypotension, PONV, respiratory depression, hypertension, COPD
COPD, RESPIRATORY DEPRESSION, HYPERTENSION, CHRONIC OBSTRUCTIVE PULMONARY DISEASE
The total incidence of respiratory adverse events in this study was 18.2% (4/44), with 2 cases of respiratory depression and 1 case of severe hypoxemia in Group S and 1 case of respiratory depression in Group E. The total incidence of hypotension was 15.9% (7/44), including 5 cases in Group S and 2 cases in Group E. The total incidence of hypertension was 11.36% (5/44), with all 5 cases occurring in Group E. The total incidence of postoperative nausea and vomiting (PONV) was 22.73% (10/44), with 6 cases in Group S and 4 cases in Group E(Table 
Baseline characteristics of the patients and details of PRFATwo-sample Student’s t-test was used for continuous data and Pearson’s chi-squared or Fisher’s exact test were used for categorical data. S, Sufentanil-Dexmedetomidine; E, Esketamine-Dexmedetomidine; ASA status, American Society of Anesthesiologists; COPD, Chronic obstructive pulmonary disease