Introduction
death, intracranial aneurysm, a ruptured cerebral aneurysm, stroke, Subarachnoid hemorrhage, permanent disability, hemorrhage, rupture, culprit aneurysm
INTRACRANIAL ANEURYSM, STROKE, SUBARACHNOID HEMORRHAGE, HEMORRHAGE, SUBARACHNOID HEMORRHAGE, RUPTURED CEREBRAL ANEURYSM
Subarachnoid hemorrhage from the rupture of an intracranial aneurysm is a type of stroke leading to death or permanent disability in most affected patients.It is common standard to occlude the culprit aneurysm by surgical clipping or endovascular coiling within 24 to 48 hours after hemorrhage, with coiling being preferred if both methods are equally feasible.We designed the EARLYDRAIN trial to investigate the effect of a lumbar cerebrospinal fluid drainage among patients with a ruptured cerebral aneurysm. Our hypothesis was that early application of a lumbar drain leads to an improved outcome after subarachnoid hemorrhage, measured by the modified Rankin Scale (mRS) score at 6 months.