Introduction
dengue
DENGUE, EROSION, MEASLES
The need for interventions and products that are personalised to human experiences and their cultural and environmental contexts is increasingly recognised. Human-centred design (HCD) has gained popularity in the field of global health as a means to co-create and rapidly assess products and services.Several studies have demonstrated the value of HCD in fostering cultural sensitivity and local adaptability.As vaccine hesitancy constitutes a significant threat to global health,While HCD-driven interventions have yielded promising results in terms of increasing vaccine confidence and uptake, their scope did not always acknowledge vaccine-hesitant families’ own lived experiences and narratives. Several authors have argued about the importance of tailoring health interventions based on vaccination concerns and experiences, and aligning interventions to fit cultural and environmental contexts.To fill gaps in the literature and lay the groundwork for a meaningful campaign that restores trust in vaccines, we drew on local narratives to design, refine and ultimately test a story-based intervention that connects vaccine-hesitant caregivers (eg, parents, other family members, legal guardians), policymakers, healthcare workers (HCWs) and other community actors. We developed and tested our HCD-driven intervention in a country that has experienced an unprecedented erosion of vaccine confidence in childhood vaccinations: The Philippines. Dramatic declines in vaccine confidence and uptake in the Philippines are linked to a dengue vaccination controversy in 2017, which sparked widespread distrust in childhood vaccinations and led to large-scale measles outbreaks and the loss of a 20-year polio-free status in 2019.In this article, we present the randomised controlled trial (RCT) results of testing the final story-based vaccine confidence intervention. Our work provides evidence that can inform upcoming campaigns and regulations targeted at restoring public confidence in vaccines.