Supplementary Materials
drowsiness, Pain, postoperative nausea and vomiting, pain, PONV
REGRESSION, POSTOPERATIVE COMPLICATIONS
Supplementary material: the supplementary material was the raw data of this study.Click here for additional data file.The CONSORT study participant flow diagram.(a) Pain score at rest. (b) Pain score upon movement. (c) Pain score upon movement in the combination group. (d) Cumulative dose of sufentanil. (e) High-sensitivity C-reactive protein (hs-CRP). (f) Knee range of motion (ROM). ▲ indicates a significant difference compared with a previous time point in the combination group, which suggests that the pain scores upon movement in the combined group significantly decreased continuously over time. a indicates a significant difference compared with the placebo group (Linear regression analysis. The mean pain score upon movement within 48 hours after surgery was the independent variable (General characteristics of the patients.ASA, American Society of Anesthesiologists. HSS score, hospital for special surgery rating scale. VAS, visual analog scale (0: no pain to 10: worst possible pain); Pain upon movement: pain upon maximum flexion. Difference is significant at the VAS pain scores and the cumulative dose of sufentanil.VAS, visual analog scale (0: no pain to 10: worst possible pain); pain upon movement: pain upon maximum flexion; difference was significant at the hs-CRP level and knee functional indicator.hs-CRP, high-sensitivity C-reactive protein; ROM, knee range of motion. a means there was a significant difference compared with the placebo group (Incidence of postoperative complications.Sedation was scored as 0 = no sedation; 1 = intermittent drowsiness; 2 = patient drowsy but arousable to verbal stimulus; and 3 = impossible to arouse verbally. PONV: postoperative nausea and vomiting; the difference was significant at the 