Outcomes
cerebral or lung infection, bleeding, postoperative nausea, cerebral edema
SECONDARY, COMPLICATIONS, BLEEDING
The primary outcome measures were the levels of hormones, including glucocorticoid (GC), ACTH, TSH, TT3, TT4, FT3 and FT4. These hormones levels were evaluated preoperatively as baseline levels (T0), 1 h after the beginning of the operation (T1), at the end of the operation instantly (T2) and 72 h after the operation (T3). The secondary outcome measures were operation duration, total fluid infusion volume, urine volume, amount of bleeding, and volumes of allogeneic and autologous transfusion. The MAP and HR upon arrival to the operating room, at the end of the operation, and their peak values were included in the secondary outcome measures. Moreover, the length of hospital stay and the incidence of complications, such as postoperative nausea, cerebral edema, and cerebral or lung infection were also recorded.