Patient and data selection
cancers, tumor, death, tumors, primary malignant neoplasm, Cancer
CANCERS, TUMOR, TUMORS, PRIMARY MALIGNANT NEOPLASM, CANCER
This study was performed based on the SEER database established by the Department of Cancer Control and Population Sciences of the National Cancer Institute (NCI) in 1973. The database collects data of patients with cancers from 18 districts in the USA, which include clinicopathology, tumor features, and therapeutic details, etc. The database (incidence-seer research plus data, 17 Registries, Nov 2021 Sub (2000–2019)) was used by our study, which covers approximately 26.5% of the U.S. population (based on the 2010 census) and contains one record for each of 8,721,474 tumors. Inclusion criteria were as follows: (1) histologically diagnosed UTUC between 2004 and 2015; 2. Patients who received chemotherapy. The exclusion criteria included the following: 1. Incomplete demographic statistical information such as age, marital status, sex, or race; incomplete clinicopathology information such as tumor-node-metastasis (TNM) stage and pathological grade; incomplete therapeutic information (the interval between diagnosis and treatment, surgical methods of the primary site, or surgery of the regional lymph node); 2. Missing survival status and follow-up information; 3. Diagnostic information from only autopsy or death certificate records; 4. UTUC was not the first primary malignant neoplasm.SEER * Stat Software (version 8.4.0.1; 