Ethics Approval, Trial Registration, and Informed Consent
The trial was approved by the Ethics Committee of the School of Public Health, Sun Yat-sen University (approval #003 in 2017). The RCT was registered at ClinicalTrials.gov under registration number NCT03860116. Written informed consent was obtained from all participants before the baseline assessment. For data analysis, all personal identifiers were removed and replaced by a research ID in password-protected data files to ensure confidentiality.