Statistical analysis.
SECONDARY
Details of sample size calculation were explained in the previous article (Baseline characteristics were expressed as mean ± standard deviation (SD) or number with a percentage. Following the CONSORT guidelines (We estimated the time to viral clearance using the Kaplan-Meier survival curves for each treatment group. For intergroup comparison of survival data, we used the log-rank test to detect the effect of nelfinavir. The hazard ratio and its 95% CI were calculated using a Cox proportional hazards model. Regarding the secondary endpoints, the cumulative viral load displayed as AUC was calculated as the sum of the product of the measured viral load and the measurement interval. The difference in AUC of viral load between the nelfinavir and control groups was evaluated using an equal variance two-sample 