Pregnancy.
hyperemesis gravidarum
SPONTANEOUS ABORTION, EVENT
Despite vigorous counseling regarding the use of contraception, three participants became pregnant during the study as described below (further details of each pregnancy are included in the An 18-year-old woman was hospitalized for hyperemesis gravidarum. Symptom onset was 19 weeks after her last dose of PfSPZ Vaccine. The remainder of her pregnancy was uneventful, and she delivered a healthy girl at 37½ weeks.A previously healthy 15-year-old had a positive pregnancy test 52 days after her second dose of 1.8 × 10A 19-year-old woman was found to have a spontaneous abortion 9 weeks into her third pregnancy and 9 weeks after her first and only dose of PfSPZ Vaccine. The temporal relationship to immunization led the team to consider the event possibly related to the vaccine. This event is further discussed below under SAEs.