Exposure to treatment
RLS
Objective measurement of TOMAC usage indicated high adherence with instructions to use devices on all days with RLS symptoms. In stage 1, participants assigned to TOMAC completed one or more device sessions on 101% of days with RLS symptoms (71% of total days). In stage 2, participants completed one or more device sessions on 97% of days with RLS symptoms (64% of total days).For subjects assigned to TOMAC, stimulation intensity was stable over time with no evidence of habituation. Average participant-selected stimulation intensity was 29.9 mA (SD: 7.0 mA) at Week 1 and 30.7 (SD: 6.9 mA) at Week 8 and there was minimal week-to-week variation within participants (week-to-week SD: 1.1 mA). Stability of average weekly intensity could not be attributed to inability or unwillingness to adjust intensity; 98% of participants used multiple intensity levels at some point during the trial.