Authors’ contributions
G.R and F.MG designed the study. E.AS and S.H drafted the paper. S.M and H.D contributed to the study design. S.H and F.J are responsible for data analysis. S.M, G.R, and E.AS are responsible for data acquisition. E.AS prepared the graphical abstract. All authors are responsible for the interpretation of data, critical revision of intellectual content, and approval of this paper.