Examples of nodules and worm sections analyzed by histology.
WORMS
Panels B-D are H&E stained sections, E-H are APR stained sections; red staining indicates that the worms are alive. A: Paraffin block with a highly calcified nodule from an IDA1 treated participant that could not be sectioned and was classified as “not able to cut, one dead female”. B: Nodule with calcified (dead) worms from an IDA3 treated participant. C: An excised nodule that was not evaluated because it was a lymph node. D-E: Consecutive sections from an IDA3 nodule with two living female worms stained with H&E and APR, respectively. F: This nodule contains a living 