Statistical analysis
gastrointestinal complaint, throat, fever
REGRESSION
All outcomes were evaluated using random effects logistic regression models using the cluster (health facility) and patient as random effects, with further adjustment using fixed effect terms for randomization stratification factorsNoninferiority was determined if the upper limit of the 95% CI of the aRR was below 1.3. All analyses based on outcomes from day 0 were performed in the per protocol population, and outcomes determined at day 7 were performed in the per protocol and complete case population (only in those for which day 7 outcomes were ascertained) and displayed accordingly unless stated otherwise. The primary analyses were performed on the first visit for an illness, with reattendance visits (a second visit to a health facility for the same illness) included in exploratory analyses. Prespecified analyses to assess the effect of the intervention in different population groups were performed by sex, age group and consultation complaint categories (respiratory symptoms, fever, gastrointestinal complaint, skin problem, ear, nose and throat problem). All analyses were performed using Stata v.16 and v.17 (ref. 