Outcomes
PONV, depression, vomiting, anxiety
SECONDARY, POSTOPERATIVE COMPLICATIONS
The primary outcome is the incidence of vomiting within the first 24 h postoperatively.The secondary outcomes include: the time to the first rescue antiemetic; the incidence of PONV assessed at 2, 6, 48, and 72 h after surgery; the severity of PONV measured by the Verbal Rating Scale (VRS) (none, mild, moderate, or severe) at the same time points; the incidence of postoperative complications; the early recovery outcomes indicators (the time of first drink, ambulate and flatus) and the postoperative LOS. Time to first rescue antiemetic was defined as the time from extubation to the first rescue antiemetic. The changes in gastrointestinal function, sleep-related quality of life, anxiety and depression status from baseline to postoperative 3 months were assessed by the Gastrointestinal Symptom Rating Scale (GSRS) [