3.7. Change in Biochemical Bone Markers including the Z-Score and T-Score by Osteo-F in Postmenopausal Women
Changes were observed in the bone mineral density and biochemical bone markers during 24 weeks in the treatment group. Among the bone markers measured by the DXA, lumbar spine BMD, bone mineral content (BMC), and T-score all tended to be increased in the Osteo-F group and decreased in the placebo group after 24 weeks from baseline, but no significant difference was observed. The lumbar spine Z-score showed a significant difference between the two groups (change: 0.07 ± 0.20 in the Osteo-F group vs. −0.02 ± 0.19 in the placebo group) when adjusting for age (