3.4. Metabolomic Analysis Reveals Daidzein as a Biomarker in CCFM1025 Intervention
The stability of the metabolomic profiles was initially assessed. As illustrated in the PCA plots (However, it is important to highlight that the relative abundance of daidzein in serum varied differently between two groups (Further investigation was conducted to examine the link between stress markers and the relative abundance of daidzein. The concentrations of stress markers, including salivary cortisol, plasma cortisol, and plasma ACTH, exhibited negative correlations with the relative abundance of serum daidzein, respectively (salivary cortisol vs. daidzein: R = −0.41, 