Introduction
Kidney cancer, cancer
KIDNEY CANCER, DISEASE, CANCER
Kidney cancer is an important cancer worldwide with an estimated 431,000 new cases globally and 81,800 new cases in the United States with a 5-year survival of 13% for stage IV disease (Pembrolizumab, a potent and highly selective humanized monoclonal anti-PD-1 antibody, has demonstrated survival benefit in combination with the VEGFR TKIs axitinib and lenvatinib in the 1 L setting (In this phase I/II, open-label study, we evaluated the safety, tolerability, and antitumor activity of pembrolizumab and cabozantinib in patients with mRCC.