Characteristics of laboratory parameters
attack-free, PFAPA, leucocytosis
INFLAMMATION, LEUCOCYTOSIS
In the group of patients with PFAPA, we analysed selected laboratory parameters associated with inflammation. Comparing the data from the acute attack and attack-free period, we observed a significant elevation of CRP during the attack (50 (17.1–120) mg/L vs. 0.95 (0.3–2.3) mg/L, p<0.0001); SAA (132 (36.65–278.25) mg/L vs. 4 (3.4–7.43) mg/L, p<0.0001); IL-6 (6.94 (1.87–20.64) ng/L vs. 1.52 (1.5-2.89), p=0.0001); alpha-1 acid glycoprotein (1.51 (1.23–1.65) g/L vs. 0.94 (0.74–1.32) g/L, p=0.0013) and in some patients also elevation of procalcitonin (0.12 (0.07–0.55) µg/L vs. 0.06 (0.04–0.10) µg/L, p=0.0185). In the attack-free period we found a significant elevation of serum calprotectin (5.92 (3.11–12.8) µg/mL vs. 3.64 (2.94–6.28) µg/mL, p=0.036) as a possible marker of subclinical inflammation.We noted a significant leucocytosis [11.95 (8.6–14.8) x 10Characteristics of laboratory parameters.Avg., average; CRP, C-reactive protein; IgD, Immunoglobulin D; IL-6, interleukin-6; IQR, interquartile range; MPV, mean platelet volume; SAA, serum amyloid A; SD, standard deviation. Individual values ​​are given as average± standard deviation for parametric variables and as median (IR) for non-parametric variables.