Author Contributions
S.D. planned the clinical study, and contributed to the conception and design of this study, as well as the acquisition and data analysis. C.D. contributed to the conception and design of this study. M.E.G. contributed to the analysis and data interpretation. M.P. planned the clinical study, and contributed to the conception and design of this study. D.C.C. contributed to the translation and critical revision of important intellectual content. All authors have read and agreed to the published version of the manuscript.