Oral VitD reduces inflammatory marker expression both acutely and longitudinally.
skin injury
Before investigating the effect of VitD on cutaneous inflammatory injury, we established the multi-omic expression profile resulting from NM injury without intervention at 72 hours after exposure (72hrs P-E). Proximity extension assays that quantify a curated panel of 92 inflammatory proteins identified 22 significantly (We then sought to characterize the acute effects of high-dose VitD intervention by analyzing DEGs and DEPs at 72 hours after intervention (72hrs P-I) relative to baseline. VitD(–) participants had 331 upregulated and 57 downregulated DEGs (To characterize the longitudinal effects of VitD intervention on NM-induced skin injury, we assessed DEGs (