Validation of PECSS
WELLS
Finally, results were validated using the independent held-out validation set. Distribution of each candidate predictor and Wells score indicator in the derivation set can be found in Table S Distribution of PECSS among patients with different PE severity grades in the derivation and validation set. Shaded areas indicate patients proportions where PE can be safely ruled out and no CTPA is needed: PECSS no higher than 4, or 4 < PECSS ≤ 6 and D-Dimer ≤ 2.5 mg/L