Outcomes
The primary outcome was the difference in the percent ischemic myocardium at follow-up imaging between the two arms. The percentage of ischemic myocardium was calculated by subtracting the total perfusion defect (TPD) at rest from the TPD at stress. However, on review of the images the core lab detected artefacts in several cases and advised to use an alternative approach to calculate the amount of ischemic myocardium from the corrected SDS values. For this purpose, we used the approach proposed and validated by Berman et al