Endpoints
weight loss, hypoglycemic, TG
EVENTS, SECONDARY
Endpoints were collected at week 16, and the primary endpoint was a change in body weight. The secondary endpoints included the proportion of patients with ≥5% and ≥10% weight loss percentages; and changes in BMI, waist circumference (WC), VFA, HbA1c, FPG, C-peptide, HOMA-B, HOMA-S, total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), SBP, and DBP. The safety endpoints included AEs, serious AEs (SAEs), hypoglycemic events, levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), and pulse rate.