Secondary outcomes
POSTOPERATIVE COMPLICATIONS
These include 30-day, 90-day, and in-hospital mortality, postoperative complications, quality of life, time to functional recovery, 2-year overall survival, 5-year overall survival, and recurrence-free survival. Surgical stress-related cytokines serum interleukin 6 (IL-6) and immunosuppressive acidic protein (IAP) will be measured before surgery and on postoperative days 1 and 7. Measurement of IL-6 and IAP levels will be performed by immunoassay using commercially available kits (MILLIPLEX