Anesthesia procedure
MUSCLE RELAXATION
Half an hour before surgery, 0.5mg of pentobarbital sodium was injected intramuscularly. Patients were all fasted for 10 hours and prohibited from drinking for 6 hours. Radial artery puncture and catheterization were performed and a 22G venous catheter needle was placed in the superficial vein of the forearm and lactated Ringer’s solution was administered intravenously. After entering the operating room, electrocardiography (ECG), heart rate (HR), invasive blood pressure (IBP), pulse oxygen saturation (SpO2), bispectral index (BIS, Covidien, USA), and train of four (TOF, GE, USA) were connected to the monitor for monitoring. After resting in the supine position for 5 minutes, SBP, DBP, MAP, and HR were measured and recorded once. The anesthetic management was standardized for all patients, using BIS and TOF as a reference. Anesthetic induction medication: Sufentanil 0.4ug/kg, etomidate 0.4mg/kg. Then the experimental drugs were obtained according to the double-blind method. After the patient’s eyelash reflex disappeared, muscle relaxation monitoring was performed simultaneously, and the experimental dose of rocuronium(N.V.Organon, Netherlands) was injected. When TOF=0, a video laryngoscope was used for nerve-monitoring tracheal intubation and a nerve-monitoring tracheal tube was placed through the mouth under video laryngoscope assistance (male: ID7.0, female: ID6.0). The electrode of the nerve monitoring tracheal tube catheter was in close contact with both vocal cords, and the electrode position was confirmed by self-checking with the neuromonitoring during surgery. The nasopharyngeal temperature was monitored during the surgery, and body temperature was maintained between 36.0-36.5°C using a balanced maintenance anesthesia approach involving propofol at a rate of 5mg/kg/h, remifentanil at 0.08ug/kg/min, and sevoflurane at 0.7 MAC. BIS value was maintained within the range of 40-60. At the conclusion of the surgery, an intravenous injection of sufentanil was administered at a dose of 10ug and flurbiprofen at a dose of 50mg.