Supplementary Materials
postoperative pain, pain
ADVERSE EVENTS
In the attachment, we have provided a total of 11 Supplemental tables, which contain the inclusion and exclusion criteria of research objects involved in this paper and the original data of data analysis, for the reference of interested friends.Click here for additional data file.Patients, included in the trial plan, underwent general anesthesia and different types of abdominal and orthopedic surgery.Patients were instructed to circle the number in the line above that reflects their current level of pain at rest and during movement. Min: minutes; h: hour.Study design.The whole clinical trial sketch.Distribution of surgery patients randomized to receive IVIB or placebo for postoperative pain. PCA, patient-controlled analgesia. FAS, full analysis set including all patients who were randomized and received at least a partial dose of IV ibuprofen or placebo; VAD, valid data set including all patients who receive at least 4 doses of IV ibuprofen or placebo as required by the study protocol; SS, safety set, including all patients who received at least a dose of IV ibuprofen or placebo and safety assessment after randomization. The efficacy assessment of IVIB during 48 h postoperatively. (a) Morphine dose during the 24 h postoperative administration. (b) VAS at rest. (c) VAS at movement. (d) The AUCs of VAS at rest (mmDemographic profiles and other information about patients.y: years, cm: centimeter, Kg: kilogram, min: minutes, ASA: American Society of Anesthesiologists. M ± StD: means ± standard deviation.AEs related to IVIB and morphine. (%) of patients.AEs: adverse events.SAEs were reported in patients.IVIB: intravenous ibuprofen; SAEs: serious adverse events.