Immunogenicity
VIRUS
The ratio of neutralizing antibody response to SARS-CoV-2 wild-type virus at day 35 for previously unexposed adolescents compared with that observed in similarly unexposed adult PREVENT-19 participants aged 18 to 25 years met all criteria for noninferiority. The GMT ratio point estimate and lower bound of 95% CI was 1.5 (95% CI, 1.3–1.7), and the lower bound of 95% CI of the serologic response difference was −1.0 (95% CI, −2.8 to 0.2) (Neutralizing antibody GMTs and serologic response were markedly higher in vaccine than placebo groups in all age subgroups (