Study patients
ascites, anaphylaxis, peritoneal infection, primary gastric cancer
ASCITES, ANAPHYLAXIS, METASTASIS, DISEASE, COMPLICATION, ONCOLOGY, GASTROINTESTINAL HEMORRHAGE, PERITONEAL INFECTION, METASTASES
Patients diagnosed with primary gastric cancer by histopathology or cytology confirmed synchronous peritoneal metastasis by biopsy of peritoneal nodules and exfoliative cytology. Other inclusion criteria were as follows: Eastern Cooperative Oncology Group (ECOG) performance status 0–2 scores, age 18 to 80, measurable or assessable lesions according to the criteria of RECIST 1.1 criteria, without other metastatic organs, and adequate organ function suitable for systemic and intraperitoneal chemotherapy. All enrolled patients underwent a multidisciplinary team (MDT) discussion. The major exclusion criteria were anaphylaxis to the drugs, massive ascites, other metastases except for peritoneal, peritoneal infection, gastrointestinal hemorrhage or obstruction, uncontrolled severe complication and underlying disease.