Intervention
encephalitis
ENCEPHALITIS
Two doses of 1 g/kg/dose of either IVIG or a matching volume of placebo were given 24–36 hours apart, with the first dose administered as soon as possible after enrolment and within five working days from the suspicion of an encephalitis diagnosis.The active treatment (IVIG) used in the study was privigen (100 mg/mL solution), manufactured and provided by CSL Behring. The placebo was a mixture of 0.9% saline and 0.1% human albumin solution, manufactured at the Royal Broadgreen and Liverpool Aseptic Production Unit, Liverpool, UK under cGMP conditions and its Manufacturer’s Importer’s Authorisation (IMP) licence.