THE CONTEXT
deaths
The incidence and mortality reports from COVID-19 in Africa have varied widely from country to country. In Niger, confirmed cases were low.Covid-19 confirmed cases and deaths in Niger from March 2020 to February 2022.Niger received a first shipment of 400,000 doses of COVID-19 vaccines produced by Sinopharm (BBIBP-CorV) on March 21, 2021As vaccines became available to healthcare workers, their priority shifted from other potential prophylaxis options toward vaccines. On April 20, 2021, the COPCOV trial site was put on pause, and the protocol was amended to account for COVID-19 vaccination, which was then being given priority. Anyone who received a COVID-19 vaccination would not be eligible for enrollment; however, participants who decided to receive a vaccine after enrollment would hitherto be followed through D90 (90 days after) or 28 days after the second dose of vaccine, whichever came later; they would also have venous blood drawn 28 days after both the first and second vaccine doses and would no longer take study medication.Despite an attempt to adapt to the availability of vaccine, enrollment did not change, highlighting additional reasons for low participation.