Statistical analysis
MR, CM, psoriasis
REGRESSION, PSORIASIS
In the present study, we evaluated the causal relationship between psoriasis and CM using various methods, including inverse variance weighting (IVW), MR–Egger regression, MR Pleiotropy RESidual Sum and Outlier (MR-PRESSO), weighted mode, and weighted median. IVW, also known as the inverse variance weighting method, is characterized by ignoring the existence of an intercept term in regression and using the reciprocal of outcome variance (seThe F statistic was calculated by the formula All analyses were performed in R (version 4.2.2; R Foundation for Statistical Computing, Vienna, Austria), and MR analysis was conducted based on the TwosampleMR (