Institutional Review Board Statement
The study was carried out according the Declaration of Helsinki and it was approved by the NHS National Research Ethics Service (NRES) Committee for University of Exeter, UK (number 15/SW/0153); the Ethics Committee of the VU Medical Center Amsterdam, the Netherlands (number 2015.160); the Ethics Committee of the University of Leipzig, Germany (number 167/15-ff); and the Ethics Committee of the Govern de les Illes Balears, Palma, Spain (number IB 2515/15 PI).