Background
infection, bone loss
INFECTION, APICAL PERIODONTITIS, BONE LOSS
Apical periodontitis (AP) is a prevalent inflammatory lesion involving teeth caused by host response to endodontic infection that leads to periapical bone loss [Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) and its anti-inflammatory properties has long been known [Root canal treatment is the established therapeutic approach for treating AP by effectively reducing bacterial burden within the root canal system. However, root canal treatment exhibits a failure rate, reported to be as high as 20% [