Trial design and participants
NSTEACS, Myocardial Ischaemia
HEART ATTACK
A parallel group, cluster randomised, registry based controlled trial was conducted at 42 hospitals in England. Clusters were an individual hospital or a group of hospitals that were participating in the UK national heart attack register (Myocardial Ischaemia National Audit Project). These hospitals were willing to manage suspected acute NSTEACS admissions with the intervention or standard care, and were not already using the GRS in routine clinical practice. Randomisation was at the cluster level because the GRS needed to be implemented in hospital and to avoid potential contamination among participants at the same hospital undergoing different management. The interventions were delivered at the cluster level and the outcomes measured at the participant level.The trial design and protocol have been published elsewhere