Pharmacokinetics of MGX over shortened i.v. infusion times.
After i.v. administration of single 1,000-mg FMGX doses over 0.5 to 3 h, peak MGX plasma concentrations increased and MGX single-dose concentration profile over shortened i.v. infusion times. Data are presented for study 1 cohorts 11a to 11d as geometric mean MGX plasma concentrations for participants in the PK population (MGX single-dose pharmacokinetic parameters over shortened i.v. infusion timesData are presented for study 1 as the geometric mean (geometric %CV) for the PK population. %CV, percent coefficient of variation; AUC