Definitions
pleural infection, fever, infection, Comorbidity, leukocytosis, Infection
RENAL, ALEUKOCYTOSIS, PLEURAL INFECTION, INFECTION, INFECTION
Comorbidities were classified according to the Charlson Comorbidity Index.Treatment failure was defined by evidence of ongoing infection, including fever and/or leukocytosis and a persistent pleural collection still present at least 48 hours following the initial intervention. Crossover treatment, independent of treatment failure, was defined by receiving any dose of IPFT following surgery or surgery following any dose of IPFT. The RAPID (Renal, Age, Purulence, Infection Source, and Dietary Factors) score for pleural infection was calculated as a validated factor associated with mortality.