Conclusion
CRPS, pain
SECONDARY, COMPLEX REGIONAL PAIN SYNDROME, CORTEX
S2‐targeted rTMS influenced sleep in patients with CRPS. Improved sleep may enhance CRPS symptom alleviation and be of clinical importance. A univariate analysis could separate the rTMS and sham treatments. The multivariate analysis revealed that including multiple sleep‐related parameters can be beneficial when analyzing rTMS effects on sleep. As sleep is related both to pain and quality of life, and sleep rTMS can be directly affected by rTMS, objective monitoring of sleep in various future rTMS trials could be fruitful.Repetitive transcranial magnetic stimulation (rTMS) targeted at the secondary somatosensory cortex decreased sleep restlessness in patients with complex regional pain syndrome. A multivariate analysis of OURA parameters revealed that assessing multiple sleep‐related parameters concurrently can be beneficial when analyzing rTMS effects on sleep. 

