Patients
malignant lymphoma, oral ulcer, MM
MALIGNANT LYMPHOMA, DENTAL DISEASES, ORAL ULCER
The current study included patients who (1) were aged 19 years or older; (2) were diagnosed with malignant lymphoma or MM and were undergoing autologous HSCT at Seoul National University Hospital; and (3) were negative for HSV IgM and positive for HSV IgG within one month before the initiation of autologous HSCT. Patients were excluded if they (1) had previously experienced Herpesviridae reactivation two more times or any recent Herpesviridae reactivation during treatment of HM before HSCT; (2) already had an oral ulcer, HSV polymerase chain reaction (PCR)-positivity of oral sample, severe dental diseases, or poor oral hygiene at the time of screening oral examination; (3) prophylactic acyclovir was either mandatory or contraindicated according to the investigators’ judgment for any other reason; (4) had a glomerulus filtration rate of less than 60 mL/min/1.73 m