Supplementary Material
Dose-limiting
EVENT
Representativeness of study participantsClick here for additional data file.Supplementary Table 2. Dose-limiting toxicitiesClick here for additional data file.Supplementary Figure 1. Time to first phenformin-related event for patients treated at the 50 mg bid dose level (N=6) and the 100 mg bid dose level (N=5).Click here for additional data file.Supplementary Figure 2. Fold change in body weight of patients by dose level.Click here for additional data file.Supplementary Figure 3. Effect of treatment on pAMPK expression in peripheral blood mononuclear cells.Click here for additional data file.