Follow-up and long-term effects of the multimodal lifestyle intervention on the ESC- SCORE
DM
There was a significant overall time effect for the ESC-SCORE in each group (INT and CON) from T0 across all follow-up time points (T2, T3, T4, T5) (Friedman test: p<0.001), which was evident in both the intention-to-treat and per protocol analyses (Delta values of the European Society of Cardiology – Systematic Coronary Risk Evaluation score (ESC-SCORE) – Intention-to-treat analysis. Means with 95% confidence intervals.Delta values of the European Society of Cardiology – Systematic Coronary Risk Evaluation score (ESC-SCORE) –Per protocol analysis. Means with 95% confidence intervals.To clarify whether there is a difference in the primary outcome between pre-DM and DM patients, a further subgroup analysis was performed for ESC-SCORE changes (