Safety assay and changes in health-related quality of life
cancer, liver and kidney functions, Cancer
ADVERSE EVENTS, ADVERSE EVENT, CANCER, CANCER
Safety was assessed by an evaluation of the clinical adverse events, which were graded according to the Common Terminology Criteria for Adverse Events (CTCAE) (version 4.0) published by the National Cancer Institute (NCI). In addition, the changes in blood routine, urine routine, liver and kidney functions, and electrolyte and coagulation functions before and after vaccination were also employed as an objective for safety evaluation.Changes in health-related quality of life were measured by the Functional Assessment of Cancer Therapy-Colorectal cancer (FACT-C) scale (version 4.0) which has been well-tested in cancer survivors and found to be reliable, valid, and responsive [