Ethics approval and consent to participate
The study was conducted in accordance with the Helsinki declaration for human research. Ethical approval was obtained from the Research Ethics Committee, Faculty of Dentistry, Alexandria University, Egypt (IRB 00010556—IORG 0008839) No. 0272–07/2021. A signed informed consent was obtained from every parent of the participating children. The trial was registered at clinicaltrial.gov registry (#NCT05761041).