Conclusion
T2DM-associated metabolic, T2DM
In conclusion, this 84-day clinical randomized controlled trial in T2DM patients demonstrates that CP displays a more beneficial effect in the alleviation of T2DM-associated metabolic phenotypes than Glipizide by regulating gut microbiota and metabolites, with no significant effects on liver and kidney function. However, these results should be considered preliminary, and large-scale clinical controlled studies are required to confirm these findings.