Conclusion
MetS, overweight
In summary, the use of an untargeted metabolomic analysis of plasma samples in postprandial women demonstrated small and transient differences in a range of AAs and several energy-related metabolites for overweight women, characterised as having the MetS, when compared to aged-matched leaner and metabolic healthier women. Further, the choice of meals used in this study did not markedly impact on the measured metabolomic responses. This study therefore cannot convincingly demonstrate whether differences in meal GL are important in altering postprandial metabolism in a manner that can either be beneficial for body weight regulation and metabolic health. However, the data emphasise the complexity of the postprandial responses to meals, composed of whole food, with the continued need to develop a more detailed understanding of the systems’ biological responses to differing meal types.