Criteria for discontinuing or modifying allocated interventions {11b}
hemodynamic impairment, CRF
CRF, COMPLICATIONS
We will exclude patients from participating in case of failure to detect the suitable anatomical structures for PECS II.After PECS II is performed, it is impossible to change the allocated intervention after administration. Subjects are free to leave the study at any time for any reason without consequences. Study discontinuation should be documented in the subject’s medical file and the case report form (CRF). The investigator can withdraw an issue from the study for urgent medical reasons. These may include the following criteria:Anatomical anomalies, limited visualizationAllergic reaction to the study medicationClinical complications (hemodynamic impairment, re-operation, extracorporeal membrane oxygenation (ECMO), etc.) that may lead to prolonged weaning (more than 24 h)