CONCLUSION
A randomized double‐blind test on different age groups and skin types were carried out to study the clinical benefit of oral administration of HA. The results indicated that oral intake of HMW‐HA (300 KDa) at the levels of 100 and 200 mg/day can promote skin hydration after 2–8 weeks, and the effect is statistically significant for both young and elderly groups. After 4–8 weeks, it could elevate the ITAHowever, there were two laminations in this study. Since the age and skin types were subdivided during analysis, the sample size of each group was relatively small, but fortunately, the entire pool was also analyzed for conclusion drawing. In addition, the study was affected by COVID‐19 pandemic, which resulted in the presence of multiple variables, especially in the middle and later stages of the test.