1. Introduction
Obesity, intestinal behavior, weight gain, satiety, overweight, adiposity, intestinal dysbiosis, weight loss
OBESITY, DISEASE, ADIPOSITY
These authors contributed equally to this work.Background: Sorghum is a cereal source of energy, carbohydrates, resistant starch, proanthocyanidins, and 3-deoxyanthocyanins; it promotes satiety by slowing digestion and benefits intestinal health. Objective: This study investigated the effects of extruded sorghum SC319 consumption on intestinal health, weight loss, and inflammatory markers in men with overweight. Methods: This was a randomized, controlled, single-blind clinical trial. Twenty-one men were randomly allocated into one of two groups: the sorghum group (test), which received 40 g of extruded SC319 whole sorghum (Obesity is a disease related to complex interactions among genetic, socioeconomic, cultural, and environmental influences. It is a disease with multifactorial causes [The inflammatory environment caused by lipid accumulation results in a non-specific activation of the immune system, contributing to a large extent to the development of alterations in intestinal behavior, altering the functionality of enterocytes and other structures, and favoring the development of intestinal dysbiosis [Studies have shown that the intestinal microbiota can influence adiposity and weight gain [Sorghum grains (