Materials and methods
head and neck, 40 brains, prostate
REGRESSION, PROSTATE
A total of 118 clinical VMAT plans, including 28 mediastina, 25 head and neck, 40 brains intensity‐modulated radiosurgery, and 25 prostate cases, were created in RayStation treatment planning system for Edge and TrueBeam linacs. In‐house scripts were developed to compute Modulation indices such as plan‐averaged beam area (PA), plan‐averaged beam irregularity (PI), total monitor unit (MU), leaf travel/arc length, mean dose rate variation, and mean gantry speed variation. Pretreatment verifications were performed on ArcCHECK phantom with SNC software. GPR was calculated with 3%/2 mm and 10% threshold. The dataset was randomly split into a training (70%) and a test (30%) dataset. A random forest regression (RFR) model and support vector regression (SVR) with linear kernel were trained to predict GPR using the complexity metrics as input. The prediction performance was evaluated by calculating the mean absolute error (MAE), 