General practice sites
WEST, RECRUITMENT
Clinical Research Networks recruited the general practices from across the National Institute for Health Research (NIHR, now referred to as the National Institute for Health and Care Research) West of England and Wessex Clinical Research Network regions. Practices were eligible if they had an adequate number of eligible patients determined by a pre-randomisation practice database search (to achieve a target recruitment of 35 participants at each site), with suitable space for treatment rooms and availability for training of healthcare professionals and baseline visits. In the final selection of practices for randomisation, we also considered representative practice list size, social deprivation score (index of multiple deprivation determined using the general practice’s postcode), and preference for how the intervention would be delivered (practice staff or trial research nurses) if the practice was randomised to the intervention arm.