Sensitivity analyses
SECONDARY
Two sensitivity analyses were performed. The first sensitivity analysis investigated the as-treated effect, by alternately defining the difference scores for continuous variables as the change from baseline to the last measure prior to discharge (rather than day 6 value). Similar statistics and tests were then carried out as described above. The second sensitivity analysis investigated a small imbalance in the baseline location of subjects (general hospital floor vs ICU). The analyses described above was repeated for the primary and secondary outcomes within the subgroup of subjects on the general hospital floor at baseline.Two-sided tests with α = 0.05 were used to evaluated statistical significance. All analyses were performed in SAS Version 9.4.