Ethics approval and consent to participate
The study was conducted across multiple countries and institutions and was approved by all relevant ethics committees and national authorities. Belgium: Medical Ethics Committee UZ Brussel—Ref 2017/122, Denmark: Capital Region of Denmark—Centre for Health—Scientific ethics Committee—Ref: H-17009698, France: Comité de Protection des Personnes Sud Méditerranée I—Ref 17 45, Germany: Technical University of Munich—Faculty of Medicine—Ethics Committee—Ref 128/17 Af, Lithuania: Lithuanian Bioethics Committee—Ref 2018–03-21 No. P-I 8–20/2, Sweden: Regional Ethical Review Board in Gothenburg—Ref 189–18, United Kingdom: London—Chelsea Research Ethics Committee—Ref 17/LO/0633. All patients signed informed consent before taking part in the study.