Plasma and CSF neurofilament light chains
CSF NfL concentration was measured using a commercially available sandwich ELISA according to the kit manufacturer’s instructions (UmanDiagnostics, Umeå, Sweden). Plasma NfL concentration was measured using the commercially available Single molecule array (Simoa) NF-Light assay (Quanterix, Billerica, MA, USA), according to a protocol previously described in detail (Gisslén et al. 