Outcome Measurements
fatigue
DISEASE
The primary study endpoint was the change in maximal exercise capacity measured by peak oxygen uptake (peak VOSecondary study endpoints included:(1) Physical fitness: submaximal exercise capacity, muscle strength, motor function, core stability, psychical activity levels.(2) Patient-reported outcomes: quality of life, fatigue, and fear of exercise.(3) Clinical disease activity: fecal calprotectin, blood draw, and validated disease activity scores.(4) Nutritional status: caloric intake, energy balance, and body composition.