Background
pulmonary embolism, DVT, hip arthroplasty, knee arthroplasty, VTE, TKA, THA
PULMONARY EMBOLISM, DEEP VENOUS THROMBOSIS, VENOUS THROMBOEMBOLISM, OSTEOARTHRITIS, COMPLICATION, DVT
Venous thromboembolism (VTE) comprises deep venous thrombosis (DVT) and pulmonary embolism (PE) and is a serious complication following total hip arthroplasty (THA) and total knee arthroplasty (TKA). Multi-modal VTE prevention using early mobilization, regional anaesthesia, mechanical and chemoprophylaxis has helped to reduce the rates of VTE after THA and TKA [Current guidelines recommend low-molecular weight heparin (LMWH), aspirin, direct oral anticoagulants (DOACs) or warfarin for chemoprophylaxis [This study aims to compare the real-world safety and effectiveness of aspirin to LMWH and DOACs in reducing symptomatic 90-day VTE rates in patients undergoing elective THA or TKA for osteoarthritis. It was hypothesized that patients receiving aspirin would have equivalent rates of symptomatic VTE when compared to LMWH and DOACs.