Randomization and Blinding
depression
A computer program performed block randomization in a 1:1 ratio, in different block sizes (4, 6, and 8), corresponding to the 2 study groups. The experimental group received specific AA (SA) for depression and usual care, and the control group received nonspecific AA (NSA) and usual care. All participants continued with their usual care for ethical reasons. Participant allocation was concealed and delivered to the acupuncturists in individual opaque sealed envelopes. Participants, evaluators, data managers, and the statistician were blinded to treatment assignment. Neither the study participants nor the investigators had any influence on randomization and allocation concealment, which an independent statistician performed. Participants were informed that there were 2 treatment protocols.