Associations between within-class FA plasma levels and changes in CMD risk markers in DIVAS
CMD
REGRESSION, INSULIN SENSITIVITY
A total of 14 out of the 41 CMD risk markers measured in the DIVAS study were linked with changes in within-class FAs using ENR models (Lipid metabolites associated with changes in cardiometabolic risk markers measured among participants from the DIVAS study (Results for the multiple linear regression models are presented in Results from multiple linear regression models on the associations between changes in within-class FA concentrations and CMD risk biomarkers in the DIVAS randomized controlled trial (Abbreviations: CE, cholesteryl ester; CER, ceramide; DAG, diacylglycerol; HCER, hexosylceramide; LDI Ach, laser Doppler imaging microvascular response to acetylcholine; LDI SNP, laser Doppler imaging microvascular response to sodium nitroprusside; LPC, lysophosphatidylcholine; LPE, lysophosphatidylethanolamine; MAG, monoacylglycerol; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PEP, phosphatidylethanolamine plasmalogen; PP, pulse pressure; QUICKI, quantitative insulin sensitivity check index; SBP, systolic blood pressure; TG, triglycerides.Multiple linear regression adjusted for age (continuous, in years), sex (female/male), BMI (continuous, kg/mExpressed as a change in CMD risk marker per additional SD of plasma within-class FA concentration (μmol/L).