Biomarker analyses
tumor
TUMOR
In predefined subgroup analyses, confirmed response rate in patients with a Activity according to biomarker subgroups: confirmed response rate.A subset of tumor tissues from 59 patients, were sequenced with a tissue panel, and no additional somatic As expected, low RAD51 was seen more frequently in patients with germline or somatic Activity according to biomarker subgroups: PFS (median, IQR, months).


Pathogenic mutations in HRR genes (not including germline and somatic 