Counterregulatory hormones in the subgroup analysis
hypoglycaemia
HYPOGLYCAEMIA
Concentrations of all five counterregulatory hormones measured appeared to increase from baseline during hypoglycaemia induction for both insulin products following double dose (ESM Fig. Counterregulatory hormone concentrations during development of hypoglycaemia following a triple dose of insulin icodec or insulin glargine U100. (A sensitivity analysis of the five counterregulatory hormones was conducted for both double and triple doses of the insulin products. This sensitivity analysis only included participants who experienced clinically significant hypoglycaemia for both icodec and glargine U100. The sensitivity analysis showed numerical results comparable to the main statistical analysis (data not shown). However, the comparisons of cortisol concentration for icodec vs glargine U100 at PG