Ethics
This study was approved by the Institutional Review Board of Seoul National University Hospital (Seoul, Republic of Korea, Approval number: 1712-125-909) and was registered at ClinicalTrials.gov (registration number: NCT03505112, date of registration: 23/04/2018, principal investigator: Jin-Tae Kim). The study was conducted in accordance with the Declaration of Helsinki, and written informed consent was obtained from all the patients. All data were collected at the Seoul National University Hospital between April 2018 and October 2021.