Assessment plan
toxicity, cancer, Comorbidity, Cancer
CANCER, CANCER
Study procedures are summarized in supplementary Table S7. Baseline assessments include a CT scan, demographics, medical history, ECOG PS, body surface area, and blood chemistry. Moreover, the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ)-C30 ver.3 is completed by the patient, and Charlson Comorbidity Index (CCI) score, Geriatric 8 (G8) score, modified Geriatric-8 (mG8) score, chair-stand-test and optional blood samples for biomarkers are done. Prior to each treatment course, hematology is evaluated. Prior to each chemotherapy cycle, toxicity, symptoms, hospitalizations, weight and ECOG PS are registered, and blood samples for biochemistry are taken.Treatment effect is evaluated every 8 weeks by a CT-scan and serum cancer antigen (CA) 19–9. At the same time, blood samples, optional blood samples for biomarkers, a chair-stand-test, and the EORTC QLQ-C30 are performed.