3.3. Bio-Appearance of Sweeteners in Healthy Volunteers
Determining bio-appearance and typical plasma levels of bioactive food compounds is essential for assessing their bio-activity. We, therefore, tested a surrogate beverage, which consisted of diet lemonade-typical concentrations of acesulfame-K (0.27 mM), Na cyclamate (1.13 mM), and saccharin (0.37 mM) in water (