Eligibility criteria
arrhythmia, seizure, epilepsy, amnestic MCI, Dementia, amnestic
EVENT, RECRUITMENT, ARRHYTHMIA, EPILEPSY
VINCI-AD will recruit both males and females with a diagnosis of amnestic MCI as determined by consensus diagnosis at the Institute of Memory and Cognition. Those eligible for inclusion in VINCI-AD will have an index delayed memory score on the Repeated Battery of Neuropsychological Status (RBANS) of less than 85 (indicative of amnestic features) and a score of 0.5 on the Clinical Dementia Rating Global scale indicating mild impairment not impacting daily function. All participants mut be on stable medications for one month prior to recruitment, must have sufficient understanding of English language and must be able to provide informed consent. VINCI-AD exclusion criteria include:
Significant current depressionUncorrected vision/hearing lossHistory of brain surgeryHistory of epilepsy with any seizure event in last yearPrescribed any pharmacological agents known to significantly increase seizure riskDiagnosed arrhythmia including atrial fibrillationCardiac pacemaker implantExisting left ear deformity or recent ear traumaAlcohol dependencePrescribed DMARDs or immunotherapies