Perfusion
migraine
MIGRAINE, DISEASE
At baseline, HCs’ perfusion exceeded that of migraineurs in four brain areas (see Fig. Baseline perfusion differences between all patients (sham and active tDCS) and controls. (Areas in which healthy controls’ perfusion exceeds that of migraineurs at baseline (p < 0.001, cluster threshold k = 44; analysis corrected for age, and sex) (see Fig. Areas in which migraineurs' baseline perfusion exceeds that of healhy controls (p < 0.001, cluster threshold k = 44; analysis corrected for age, and sex) (see Fig. Next, we compared CBF differences between the active and sham tDCS groups at different time points. There was a main effect of group (FAreas in which the perfusion of patients in the active tDCS group exceed that of those in the sham group exceeds at the first follow-up examination (F1), which was scheduled directly after the stimulation period (p < 0.001, cluster threshold k = 44; analysis corrected for age, disease duration (years), aura, and migraine days during the baseline period) (see Fig. The graphic indicates post-tDCS (time point F1) perfusion in patients. (Areas in which the perfusion in the sham group exceeds that of patients in the active tDCS group at the first follow-up examination (F1) that was scheduled directly after the stimulation period (p < 0.05, cluster threshold k = 44; analysis corrected for age, disease duration (years), aura, and migraine days during the baseline period) (see Fig. At F2, there was no brain area with increased perfusion in the active group participants compared with the sham group and, conversely, no area with increased perfusion in the sham group participants compared with the active group.