What did the researchers do and find?
CERVICAL CANCER, CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN)
This population-based study including a total of 44,579 women showed that a catch-up HPV screening intervention, with the opportunity to choose between clinician-based sampling and vaginal self-sampling, was associated with significantly higher detection of cervical intraepithelial neoplasia (CIN) grade 2 or worse (CIN2+) per 1,000 eligible women as compared to women not offered screening.This study demonstrated that women who have been insufficiently screened at age 50 to 64 (≤1 cytology sample) had higher HPV prevalence and tended to have more CIN2+ lesions diagnosed as compared to sufficiently screened women (≥2 cytology samples).Insufficiently screened women were more likely to undergo vaginal self-sampling as compared to sufficiently screened women, which supports that this screening modality might be ideal to identify older women at risk of cervical cancer.