Introduction
nerve palsy, swelling, vomiting, end-stage knee arthritis, pain, knee arthroplasty, muscle injury, TKA
INFLAMMATION, NERVE PALSY, INTRAOPERATIVE BLOOD LOSS, DEEP VEIN THROMBOSIS
Total knee arthroplasty (TKA) is considered the most effective therapy for patients with end-stage knee arthritis because it can relieve pain and improve joint function [Applying tourniquets during surgery can maintain a clear surgical field by reducing intraoperative blood loss, thereby shortening the operation time. However, their use in orthopedic procedures such as TKA is controversial, given that they can increase the risk of postoperative thigh pain, limb swelling, nerve palsy, muscle injury, and deep vein thrombosis [We wondered whether the disadvantages of tourniquets would be mitigated by the perioperative dexamethasone typically used during TKA to inhibit postoperative inflammation, vomiting, and thigh pain [Here we tested the safety and efficacy of applying tourniquets to patients undergoing cemented TKA involving multiple doses of dexamethasone and tranexamic acid.