Biosampling and measurements of the microbiome
STERILE, SECONDARY
The secondary outcome is considered the bacterial composition. Both saliva and gingival fluid will be collected from the participants. Gingival fluid between the teeth will be collected with sterile paper points at 6 per-protocol predetermined sites in the lower jaw (mesial and distal at the “Ramfjord” teeth 41, 44 and 36) and 6 sites in the upper jaw (mesial and distal at the “Ramfjord” teeth 21, 24, 16). The samples will be frozen directly after collection, in separate vials for the upper and lower jaw samples. Saliva will be collected as well. Subjects are asked to chew for 1 min on a paraffin gum.