The effect of LSD on inhibitory self-connections
As pointed out in the Introduction, an advantage of using EC over FC is that rDCM allows estimation of inhibitory self-connections (see Supplement). These all-negative values can be interpreted as ‘decay-rate’ coefficients (in view of the DCM state equation) since they capture the tendency of different regions to return to baseline, rather than increasing activity indefinitely. Also note that these values reflect local as opposed to global (inter-regional) dynamics.Mass-univariate tests suggested that about 30% (39/132) inhibitory self-connections significantly differed across conditions (