Inclusion and exclusion criteria
numbness
Seventy‐two patients referring to the Endodontics Department of Tabriz Dental School, who met the following inclusion criteria, were randomly selected and evaluated. The inclusion criteria consisted of the following:
Systemically healthy patientsAge range 18–65 yearsLack of sensitivity to epinephrine and sodium hypochloriteNo facial paresthesiaNot having taken any painkillers within 12 h before treatmentNot having taken any medications interfering with anesthesiaNo history of traumaNo periodontal diseaseCompleting an ethical questionnaire and being willing to participate in the studyHaving mandibular molar teeth with symptomatic irreversible pulpitisThe exclusion criteria included the following:Patients not meeting at least one of the inclusion criteriaNot achieving lip numbness 15 min after block injectionPregnancy and lactationSevere periodontal diseaseTeeth that could not be isolated with a rubber damRoot canal calcificationTeeth with severe irreparable cariesUse of a specific drug or medication