Background
critically ill, Traumatic brain injury, TBI, AKI, acute kidney injury
CRITICALLY ILL
Traumatic brain injury (TBI) remains a worldwide health priority [Prospective and retrospective clinical studies have reported an association between chloride intake and AKI in critically ill patients [This post hoc analysis of the COBI trial aimed at determining whether high dose of chloride delivered by hypertonic saline solution infusion were associated with an increased acute kidney injury incidence within the 28 days after the infusion compared to standard care in TBI patients.