Event accrual patterns
MAY, EVENT, RECRUITMENT
For this analysis, the following time windows were calculated: time from event occurrence to site reporting, time from site report to adjudication packet complete (marked by packet sent for review), and time for adjudication to be complete (marked by adjudication decision recorded). Total adjudication time was the time from event occurrence to a recorded adjudication decision. Time windows are reported as median (25th, 75th percentile) and were calculated by event type and according to the phase of trial operation: recruitment (December 16, 2008–July 31, 2012), follow-up (August 1, 2012–May 4, 2014), or close-out (May 5, 2014–March 30, 2015).