Discussions
ischemia, TKA, hypotension
POSTOPERATIVE DEEP VEIN THROMBOSIS, ISCHEMIA, COMPLICATIONS, DEEP VEIN THROMBOSIS
The most important finding of our study was that applying a tourniquet to patients undergoing cemented TKA involving multiple doses of dexamethasone and tranexamic acid reduced IBL without increasing HBL or the risk of complications. It also significantly shortened surgery and reduced intraoperative controlled hypotension requirements.Several studies have shown that tourniquets can reduce IBL and thereby help ensure a bloodless surgical field in orthopedic procedures such as TKA [In addition, we found that tourniquet use did not increase HBL, in contrast to previous work [Like a tourniquet, hypotension anesthesia during TKA has been reported to provide a clear surgical field as well as reduce HBL and the risk of deep vein thrombosis [Applying tourniquets during TKA has been shown to increase the levels of the inflammatory factors CRP and IL-6, probably as a result of ischemia and damage to soft tissue [Xie et al. have reported that using a tourniquet could increase the incidence of postoperative deep vein thrombosis [Our results should be verified and extended in studies with a longer follow-up in order to detect delayed or long-term complications. Future work with a longer follow-up should examine the safety and efficacy of tourniquets for patients undergoing cemented TKA involving multiple doses of dexamethasone and tranexamic acid, as well as the effects of tourniquets on the speed and extent of joint function recovery, based on the repeated measurement of the postoperative ROM. Ultimately, our findings should be validated with large multicenter studies.