Discussion
ischemia, myocardial ischemia
ISCHEMIA, MYOCARDIAL ISCHEMIA
This study is the first to describe the pattern of temporal changes in metabolites after myocardial ischemia in humans using There are a few previous studies of metabolic changes from similar experimental setups of induced ischemia in humans (Bodi et al., We expected to see an increase in lactic acid as a result of the myocardial ischemia inhibiting the TCA cycle leading to an increase in anaerobic metabolism. However, this increase was relatively slow only materializing 1–2 h after the ischemia. This delay was not observed in a similar previous study, in which lactic acid was elevated as early as 20 min post induced ischemia (Bodi et al., 