Ethics approval and consent to participate
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This trial was approved by Institutional Review Board/Chang Gung Memorial Hospital (file number 202102115A3) and registered at clinicaltrials.org (NCT05253404) on 23 February 2022. Informed consent: A written informed consent was obtained from each participant included in the study.