Study population
pheochromocytomas/paragangliomas, tumour
CARCINOIDS, TUMOUR, DISEASE PROGRESSION
Eligible patients were aged ≥ 18 years with histologically confirmed, unresectable grade 1/2 gastroenteropancreatic (GEP)-NETs, typical or atypical lung carcinoids, or pheochromocytomas/paragangliomas, with documented disease progression, according to RECIST version 1.1, under prior anti-tumour therapy within the past 6 months prior to study entry. Patients should not have received further anti-tumour therapy once disease progression had been documented. Patients were required to have confirmed presence of SSTR on technically evaluable tumour lesions, documented via a positive SSTR scan. Patients were required to have at least one tumour lesion in part A and at least two tumour lesions in part B ≥ 2 cm with an uptake on SSTR imaging higher than that of normal liver parenchyma (target lesion on [Key exclusion criteria were pregnancy, diagnosis of thymic NET, PRRT at any time before the study, and extensive radiotherapy or chemotherapy ≤ 3 months before study start.