Efficacy in the mild DED subpopulation
conjunctival redness
DISEASE
The subgroup with mild disease showed no significant differences in mean change from baseline compared to placebo. Inferior corneal staining, total corneal staining, conjunctival redness, ocular discomfort, and eye discomfort all showed improvement with PL9634 administration, but none was superior to placebo. Mean tear film breakup time stayed level over the duration of the study but was not better than placebo at any visit.