Cellular and developmental bases of repetition suppression differences
CORTEX
Though we cannot establish what cellular differences in ASD explain the weak repetition suppression, there are converging observations from preclinical studies. First, it has been demonstrated that GABAergic somatostatin-positive interneurons (SOMs) selectively suppress responses to repetitive standards but not deviants in the primary auditory cortex in mice [Preclinical examination of SSA suggests that postsynaptic GABA