Analysis of variant emergence dynamics and distribution during the study period in participants and other hospitalized patients.
VIRUS, DISEASE, DELETION
(Enrolled participants exhibited a higher prevalence of chronic medical conditions compared to other hospitalized patients admitted with severe COVID-19 during the same period and treated under the same standard-of-care, who were used as historical controls (Dynamic changes in serum levels of CRP and NLR, which mark the immunoinflammatory progression of the disease, also demonstrated favorable trends (Patients treated with nanocrystallized fenofibrate also exhibited lower mortality, lower respiratory intervention rates, and significantly increased withdrawal rate from supplemental oxygen by day 7 (weighed difference of 26.1 percentage points; 95% CI, 7.0–45.2; p=0.003; Novaplex SARS-CoV-2 variant analysis showed a dominant presence of 69/70 deletion and N501Y substitution mutation correlating to the B.1.1.7 (UK) variant of the virus in the patient population (