Construction of a predictive gene-signature for postoperative seizure occurrence
postoperative seizure, seizure
REGRESSION
LASSO logistic analysis of DEGs was used to identify genes with the highest ability to predict postoperative seizure occurrence. Seven genes: Construction and receiver operating characteristic (ROC) analysis of a gene-signature for postoperative seizure occurrence using Lasso logistic regression analysis. Postoperative seizure occurrence associated genes identified via lasso regressionRisk score = 0.000646822 * ExpROC analysis was used to test the predictive capacity of the gene-signature in the training and validation cohorts, and AUC values of 0.842 and 0.75 were obtained from the respective cohorts (Fig. 