Research participants
sore throat, allergic, liver and kidney dysfunction, arrhythmia, fatigue, bacterial infection, heart disease, stuffy nose, cough, pulmonary exudative lesions, headache, muscle aches
SORE THROAT, ARRHYTHMIA, BACTERIAL INFECTION, HEART DISEASE, HIV INFECTION, UPPER RESPIRATORY TRACT INFECTION, INFLUENZA, INFLUENZA
To further explore the effect of arbidol hydrochloride in the treatment of influenza-like cases, a total of 427 subjects meeting the clinical diagnosis criteria of influenza in the draft Guidelines for Clinical Diagnosis and Treatment of Influenza (draft) [
Flow chart of enrolled influenza-like casesThe registration number is ChiCTR2100043928, and the date of registration was 5/3/2021.The criteria for inclusion and exclusion were developed based on previous multicenter studies of oseltamivir and arbidol [Inclusion criteria: (1) signed informed consent; (2) age ≥ 18 years; (3) body temperature ≥ 37.5 °C, and (4) influenza-like symptoms: stuffy nose, sore throat, cough, muscle aches, fatigue, headache, chills/sweating, etc., with no diagnosis other than upper respiratory tract infection.Exclusion criteria: (1) patients with allergic history and/or severe allergic constitution; (2) severe liver and kidney dysfunction; (3) high likelihood of bacterial infection based on signs, symptoms, or laboratory tests; (4) development of pulmonary exudative lesions; (5) severe heart disease that researchers believe will affect the safety of subjects or clinically significant arrhythmia (according to ECG or medical history); (6) influenza vaccine taken within 12 months; (7) known HIV infection; (8) pregnant or lactating women; and (9) laboratory-confirmed COVID-19.