Introduction
fatigue, MUPS, pain, dizziness, Neurosciences-based
Medically unexplained physical symptoms (MUPS) are defined as physical complaints such as pain, fatigue and/or dizziness for which no pathophysiological explanation can be found after adequate medical examination [Many patients with MUPS have a good prognosis. Fifty to 75% of the patients with MUPS improve within one year. Yet, unfortunately approximately 10 to 30% deteriorate [Much research has been conducted on effective interventions for chronic MUPS. Neurosciences-based therapeutic education, cognitive behavioral therapy, and exercise therapy have been shown to be effective treatment modalities in patients with chronic MUPS [For GPs, adequate management of chronic MUPS is challenging, given the unexplained background and high consultation frequency [We demonstrated in earlier research that patients with moderate MUPS can be adequately identified using data of the electronic medical records of the GP [We developed a proactive, blended and integrated multidisciplinary intervention (PARASOL) for patients with moderate MUPS in primary care with the aim to prevent chronicity [