Safety
ADVERSE EVENTS, ADVERSE EVENT
Safety endpoints included treatment‐emergent adverse events (TEAEs), serious adverse events (SAEs), DLT, standard clinical laboratory parameters, vital sign measurements, electrocardiogram parameters, physical examination findings (including ECOG PS), left ventricular ejection fraction (ECHO/MUGA findings), and ophthalmologic and pulmonary findings. Adverse events (AEs) were coded using Medical Dictionary for Regulatory Activities (MedDRA) and MedDRA/J version 21.1.