Recruitment
anxiety, depressive disorders
Participants were recruited via social media advertisements and an email database between March and June 2022. Interested volunteers were directed to a website that provided details about the trial and a link to complete an online screening and application form. Before completing this application, volunteers were required to agree to provide such background information; however, an informed consent form was not completed until after the telephone interview, where applicants eligibility to participate in the study was further assessed. The application form included questions to obtain relevant background details, health history, medication use, supplement use, drug and alcohol use, and questionnaires comprising the Patient-Reported Outcome Measurement Information System-29 (PROMIS-29)—Fatigue Subscale and the four-item Patient Health Questionnaire (PHQ-4), which is a reliable and valid brief self-report measure to detect anxiety and depressive disorders in adults (