Data analysis
OBSTRUCTED LABOUR
Data were analyzed using Stata version 17.0 (Stata Corp LLC, College Station, Texas, United States of America). We summarized continuous variables using means with standard deviations or medians with interquartile ranges and categorical variables using their frequencies and percentages.We constructed receiver operator curves (ROC) to compare the predictive ability of maternal lactate at baseline and one hour after administration of study drug, myometrial lactate, umbilical venous and arterial lactate at birth using Stata’s ‘roccomp’ command. Optimal cut-off values for predicting perinatal mortality and early neonatal mortality were determined for maternal lactate on admission with obstructed labour and one hour after administration of study drug, myometrial lactate, and umbilical venous and arterial lactate at birth using the maximal Youden Index and Liu’s index. Youden’s index objectively calculates the optimal cut-off. It takes into account the sensitivity and specificity and it is used to estimate the diagnostic effectiveness of various cut off points [