Patients
carcinoma of the breast
ONCOLOGY, DISEASE, CARCINOMA OF THE BREAST
Male or female patients ≥ 18 years who had histologically confirmed locally advanced, unresectable or metastatic carcinoma of the breast of all subtypes were eligible to enroll with no limitation on prior lines of therapy. Eligibility included an Eastern Cooperative Oncology Group performance status (ECOG PS) of 0–2, measurable disease, adequate organ and bone marrow functions (neutrophils > 1.0 × 10