Author’s Contributions
All authors contributed to the study conception and design. Patients were assisted by G. S., A.C., A.L., A.B., M.T., V.P and D.V. Material preparation, data collection and analysis were performed by G.S., A.L., A.C, A.B., V.P. Analysis were performed by A.C, G.S, A.L. The first draft of the manuscript was written by G.S., and all authors commented on previous versions of the manuscript. Tables and figures were prepared by G.S., A.L. and A.C. All authors read, reviewed and approved the final manuscript. All listed authors have approved the manuscript before submission, including the names and order of authors.