Data collection
The enrolment inclusion criteria included an age of 16 or older (as per the Rayscape technical requirements), a non-contrast CT examination and positive RT-PCR results confirming COVID-19. The entire enrolment flow is illustrated in Fig. Chest CT investigations were performed using NeuViz 16 Essence (Neusoft Medical Systems), Revolution EVO (GE Healthcare) and MX16 (Philips Healthcare) scanners with slice thicknesses ranging from 1.25 to 1.5 mm.As the reference standard involvement percentages in the retrospective analysis and the clinical trial, two non-participating radiologists with at least seven years of experience in thoracic diagnostic radiology manually annotated all images at the pixel level using the ePAD