Conclusions
cancer, weight loss
CVD, CANCER, MINOR, DISEASES
The clinical implication of the findings of this cohort study is that physicians should be aware of the significant association with mortality of even relatively minor weight loss (≥5%), especially among older men. The risk extends beyond an increased risk of cancer, extending to CVD and a range of other life-limiting conditions. Further research will be needed to determine more precisely the association between weight loss and the onset of fatal diseases and whether clinical or laboratory investigations can identify individuals for whom early intervention may be effective.