Differential gene expression and TME in patients with different responses
ADHESION
Next, the transcriptome data and their association with responses were analyzed. We identified 209 differential expression genes (DEGs) between baseline samples of patients with MPR and non-MPR. These DEGs were mainly enriched in metabolisms of vitamin and fat, cell to cell/matrix adhesion, and multiple signaling pathways, including PI3K-Akt, MAPK, Ras, and Wnt pathways (Fig. 