Statistical Analysis
SECONDARY
We followed the intention-to-treat approach and conducted all analyses at the level of the participating unit. We compared primary and secondary outcomes between treatment groups using a generalized estimating equations approach with an unstructured working correlation matrix to adjust for clustering. We performed multivariate analysis using generalized estimating equations to adjust for covariates, including baseline adherence. Analyses were completed using R, version 3.5.3 (R Foundation for Statistical Computing) on April 25, 2019. Statistical significance was defined as a 2-sided 