Supplements
D9-phosphorylcholine chloride
The deuterium-labelled (D9) analogues choline-d9 chloride [N,N,N-trimethyl-d9] (D9-choline chloride), D9-phosphorylcholine chloride, calcium salt (D9-phosphorylcholine), D9-alpha-glycerophosphorylcholine (D9-GPC) and D9-1-palmitoyl-2-oleoyl-glycero-3-phosphorylcholine (D9-POPC) were from EQ Laboratories GmbH (Augsburg, Germany). Pure substances were aliquoted into screw capped opaque glass vials by Rainfarn-Apotheke (RAINFARN Gesundheit, Munich, Germany). Substances were delivered as dry substance for oral application in suitable quantity for a single administration of 350 mg D9-choline chloride, 620 mg D9-phosphorylcholine, 620 mg D9-GPC and 1.8 g D9-POPC to achieve a single dose of 2.7 mg/kg D9-choline equivalent.