SCC dynamics delineate the depression state
We extracted spectral features from LFP recorded with stimulation turned off for the classification of ‘sick’ versus ‘stable response’ (that is, the first 4 weeks and the last 4 weeks of the 24-week observation period) in the typical responders. A neural network classifier (with leave-one-participant-out cross-validation) was able to distinguish the ‘sick’ and ‘stable response’ states (area under the receiver operating characteristic (ROC; AUROC): 0.87 ± 0.09; Fig. 