Statistical methods
ADVERSE EVENTS
All statistical analyses were performed using SAS version 9.4 statistical professional analysis software. Measurements were reported as the mean standard deviation. Continuous measurements were compared using the t-test, and count data were analyzed using the chi-squared test. The Wilcoxon rank-sum test was used for intergroup comparisons. The safety analysis was based on descriptive analytics. The adverse events and the incidence in each group were listed in the table and compared using the chi-square test or Fisher’s exact test. Statistical significance was set at P value < 0.05.