Intervention and treatment protocol
BLIND
Minoxidil and placebo were blinded by SAS9.4 software. Patients and researchers were blinded to the treatments. All patients were randomized by assigning blinded drugs and then allocated into two treatment arms:

All patients received subcutaneous injections of PRP treatment (three times injections, at monthly intervals), combined with blind drugs use topically (twice a day for 3 months). Group A received treatment with topical 5%minoxidil (Shanxi Zhendong Ante Biopharmaceutical Co., LTD. [60 ml, 3g]), and group B was treated with a placebo topically.