Statistical analyses
CRS-R, spasticity, RTT
SECONDARY
After data collection eleven patients had to be excluded from further analyses because of missing data (interruption during the study period due to transfer to the acute hospital at T3, n = 1; drop-out follow-up at T5, CONSORT-guidelines based flow of patients through the study. Demographic, behavioral and outcome data were checked for normal distribution and homogeneity of variances. If normality or homogeneity of variances could not be assumed, non-parametric tests were applied (i.e., Kruskal–Wallis rank sum test when comparing three treatment groups and Wilcoxon rank sum and signed rank test when comparing the two RTT treatment groups against the control group). When testing for the improvement in DoC categories, a proportional test (Pearson’s Chi-squared Test for count data) was applied. Correlations between outcome variables (time of verticalization with CRS-R modified score, gamma band functional connectivity or spasticity) were tested using the Spearman correlation coefficient.Since total randomization numbers were low, we also performed a secondary exploratory analysis, where both RTT groups (−F and +F) were combined and compared to the control group (CPT).