5. Conclusion
chronic disease, Pain, UC
CHRONIC DISEASE
Exposure to the proposed intervention program was not able to produce a significant difference between comparative groups in medication adherence for non-adherent patients with UC. We suggest that in future studies, outcome differences of lesser magnitude for sample calculation, shorter intervals for measuring adherence using more than one method, higher frequency of educational interventions and inclusion of new forms of interaction between patient and care team should be considered.In this research, the intervention program demonstrated a significant improvement for QoL, specifically for the domains of "Pain", "Vitality" and "Emotional aspects". This result is extremely important for UC patients, as it is a chronic disease with a recognized negative impact on QoL.