Study Design
NRS, pain
The study was randomized, double-blinded, sham-controlled and cross-over and consisted of one preparatory and three experimental sessions. In the preparatory session, subjects were acquainted with RIII recording, pain intensity rating (NRS), and the CPM test. The experimental sessions were identical apart from type of t-DCS (anodal, cathodal, or sham in randomized order) and at least 7 days apart.We assessed t-DCS effects on a wide range of pain and pain modulation measures at 0, 30, and 60 min after stimulation (“post”), compared to baseline [Outline of experimental procedures. The three experimental sessions were identical apart from type of t-DCS (anodal, cathodal, or sham in randomized order). The stabilization period was used to establish a steady RIII response, subsequent measurements (baseline, 0/30/60 min post and CPM), during which the different methods described above were used, results recorded and evaluated after each session