Analysis plan
REGRESSION, RECRUITMENT
Each potential response on the ACT-Q was scored on the participant’s rating of its importance to their decision making process and the mean score for each aspect was be represented.The independent variables in this study were the study questionnaires and clinical data from CARE–MND. The binary dependent variable was the decision to participate, or not, in MND–SMART. To determine which factors affected recruitment into the trial, logistic regression was used to model aforementioned independent variables on the dependent variable. Results were presented with odds ratio and 95% confidence intervals.To determine which factors affected trial retention, we used univariate and multivariable logistic regression to explore the effect of the independent variables on withdrawal from the trial at the 12-month timepoint (dependent variable). Results were displayed as odds ratios and 95% confidence intervals.