Outcomes
deaths, death
The dual primary endpoint was defined as (1) total 24 h natriuresis at day 1, and (2) time to first occurrence of all-cause mortality or HF rehospitalization until 180 days after randomization. Secondary endpoints were total 48 h natriuresis, total diuresis at 24 h, total diuresis at 48 h (0–48 h), length of hospital stay from baseline to discharge, time to first HF rehospitalization, number of HF rehospitalizations, time to death from any cause, number of deaths, and percentage change in NT-proBNP at 48 and 72 h. All rehospitalizations were adjudicated by the endpoint adjudication committee to judge whether a hospitalization was due to HF (Supplementary Note 