RPS promotes an increase in intestinal butyrate after allogeneic HCT
Stool specimens were collected from study participants at baseline before conditioning (day −7), nadir (approximately days 5–7), engraftment (approximately day 14) and day 100 (Fig. To determine whether a regular and defined quantity of RPS impacted the host microbiome and its metabolites despite potential regular diet variation and standard mandated antibiotic use after HCT, we performed targeted metabolomic analyses on longitudinally collected stool specimens using HPLC to quantify the absolute amount of butyrate (Fig. 