Introduction
Frailty, mood alterations
SYNDROME, DISEASES
Population ageing and longer life expectancies bring new challenges for geriatric care and research [Frailty has important implications for clinical practice. As an indication of risk of poor clinical outcomes, frailty assessment can inform clinical decisions and enable avoidance of potentially harmful treatments. As an indication of decline in capacity, associated with but not dependent on diseases, frailty can potentially be stopped or even reversed with adequate treatment.There is growing evidence that homeostatic instability is a result of the inadequate interaction between the multiple systems [Frailty is not a static syndrome, but one in which there is variable decline and interactions between frailty dimensions over time. Physiological capacity may fluctuate over time and individuals can transition from different frail states [Describing longitudinal frailty along the different metrics can yield a better understanding of the overall frailty syndrome and its progression in late-life. The aim of this study was to describe the longitudinal correlation between five frailty metrics, namely multimorbidity, muscular strength, mood alterations, cognitive capacity, and functional capacity, in a prospective 1-year follow up of a cohort of aged care residents.