ACCOUGH
cough, HNC
The primary outcome is the identification of a set of descriptive acoustic cough features in healthy subjects as reference data for comparison with HNC patients. This outcome is addressed via two methods of analysis: a temporal analysis and as spectral analysis. The temporal features include the signal duration as well as shape features of the amplitude, the sample entropy and the kurtosis contours. The spectral features are the relative signal energies in the bands (0–400 Hz, 400–800 Hz, 800–1600 Hz, 1600–3200 Hz), the interval between 3200 Hz and half the sampling frequency (22,050 kHz) and the weighted frequency.