Methods
allergy, hypertension, asymmetric brow ptosis, disorder of the eyelid or sequelae
DERMATOCHALASIS, ALLERGY, FACIAL PARESIS, ADVERSE REACTION, METABOLIC SYNDROME, HYPERTENSION, DISEASES
The Ethics Committee of the Medical University of Vienna, Vienna, Austria approved the protocol of the present study (ClinicalTrials.gov: NCT04924972), which was conducted in adherence to the Declaration of Helsinki including current revisions and the Good Clinical Practice (GCP) guidelines. Written informed consent was obtained from all patients participating in this study before study inclusion.In this randomized, patient- and observer-blinded cohort study, we included 90 female or male patients, 18 years or older, with bilateral dermatochalasis.Patients were not included if any diseases affecting wound closure or healing were present. Further, untreated hypertension or metabolic syndrome, smoking, asymmetric brow ptosis, and any other disorder of the eyelid or sequelae after facial paresis were considered an exclusion criterion. A known allergy or adverse reaction to any substance used was also considered an exclusion criterion.