Ethical statement
This prospective trial was registered in the WHO International Clinical Trials Registry (DRKS00024205) on 2021/03/03 and approved by Ethics Committee of the Friedrich-Alexander University Erlangen-Nuremberg (Reg no. 21_21B) on 2021/02/03). Written informed consent was obtained from all study participants. All methods were performed in accordance with relevant guidelines and regulations/declaration of Helsinki. Informed consent was obtained from all subjects and/or their legal guardian(s) for study participation. This manuscript has been compiled in accordance with the Consolidated Criteria for Reporting Qualitative Research (COREQ) (Supplemental File 4).