Study design and population
MAY
This prospective randomized controlled trial was conducted on 80 patients indicated for septoplasty under general anesthesia. Patients were randomly assigned into one of two groups; the first group (40 patients) received intra-operative Nitroglycerine (Nitroglycerine group) and the second group (40 patients) received intra-operative Phentolamine (Phentolamine group). Randomization was carried out using a closed opaque envelope technique where the physician picked up a sealed envelope containing a card having the name of the group to which the patient was randomly selected. Whatever group was written on the card, the patient was scheduled to it.The patients were recruited from Otorhinolaryngology surgery department, Beni-Suef University Hospital, from January 2020 to May 2021. The study was registered in ClinicalTrials.gov on 1/10/2019, and this is the identification number NCT04110808.