Conclusions
lower limb lymphedema, PCD
In this preliminary study, perometry and BIS were shown to be the better measurements to determine the response to PCD treatment, while tonometry, US, and TDC were of lesser utility. The findings indicate a potential benefit for 1 hour of daily treatment compared with twice-daily treatments of 1 or 2 hours. A future definitive randomized controlled trial design is proposed. These data are also of wider value in informing the design of other studies examining the outcome of interventions for the treatment of lower limb lymphedema.