Introduction
HSDD, hypoactive sexual desire disorder, low sexual desire
The human sexual response is crucial for reward, satisfaction, and reproduction.One of the most common forms of low sexual desire is hypoactive sexual desire disorder (HSDD), which affects up to 8% of men.The neuropeptide kisspeptin is a crucial endogenous activator of the reproductive system,To test our hypothesis, we used physiological, behavioral, functional neuroimaging (functional magnetic resonance imaging [fMRI]), and hormonal analyses to investigate the clinical and mechanistic effects of kisspeptin administration in men with HSDD.