Statistical analysis
LME
Baseline comparison of the three groups was conducted using analysis of variance, followed by pairwise comparison using Fisher’s least significant difference test. To assess rate of change in cognitive performance, group comparisons on each cognitive outcome were conducted using linear mixed-effects (LME) modelling analysis with random effects for intercept and slope and group-by-time interaction. Time was expressed as number of weeks from baseline to follow-up. The LME analysis included all cases with data on at least one timepoint (of 118 total participants, 84 had cognition data at both timepoints, and 34 only had data at baseline). Significant group-by-time interactions were followed by pairwise comparisons with effect size indexed using partial eta squared (