Introduction
choroidal abnormalities, chorioretinal disease
SECONDARY, DETACHMENT, CENTRAL SEROUS CHORIORETINOPATHY
Central serous chorioretinopathy (CSC) is a chorioretinal disease that causes detachment of the neuroretina due to accumulation of subretinal fluid (SRF). This accumulation of SRF, typically under the macula, is thought to be secondary to choroidal abnormalities that induce damage to the outer blood-retina barrier at the level of the retinal pigment epithelium [The classification of CSC is subject of controversy, but CSC can roughly be categorized into acute and chronic (cCSC) forms [Commonly used treatments for cCSC include half-dose photodynamic therapy (PDT), oral eplerenone, and high-density subthreshold micropulse laser [Although half-dose PDT appears to be the treatment of choice in cCSC, it is unknown if half-dose PDT is also superior to eplerenone treatment on long-term follow-up. In this follow-up study of the SPECTRA and SPECS trial, we describe the outcome of cCSC patients at 12 months after the primary treatment with either eplerenone or half-dose PDT and crossover treatment, in terms of the desired anatomical effect (complete SRF resolution on OCT) and functional parameters.