Pharmacokinetics
All patients were sampled for PK analysis, but only 17 and 18 of them were suitable for NCA of plitidepsin and BTZ, respectively. Mean total body clearance (CL) and volume of distribution (Non‐compartmental pharmacokinetic parameters
Abbreviations: AUC, area under the concentration–time curve from time zero to infinity; BTZ, bortezomib; CL, total clearance; CL/F, total clearance of drug after extravascular administration, corrected for absolute bioavailability; 