Methods
Considering the relative rarity of GP, we adopted a historical control study design (the interventional arm was established by prospectively recruiting newly diagnosed patients, while matched historical cases were set as the control arm). The study was approved by the Ethics Committee of the First Hospital of Shanxi Medical University (202206722) and prospectively registered on the Chinese Clinical Trial Registry website (ChiCTR2200059953, date of first registration: 14/05/2022).