STUDY DESIGN
RECRUITMENT
A single-center, two-arm, randomized control trial with split-mouth design was
conducted on subjects recruited from the Department of Orthodontics at Surendera
Dental College and Research Institute (January 2021-July 2021). The split-mouth
design was chosen to avoid interpersonal variations in the study. Ethical
clearance was obtained from the Institutional Ethical Committee
(SDCRI/IEC/2020/012), and the trial was registered in the Clinical Trials
Registry of India (CTRI) (REF/2022/02/051837). Informed consent was obtained
from patients and/or legal guardians, prior to recruitment. The CONSORT
statement was followed as a guide for this study (
