4.2. Endothelial Function
hypertension
TYPE 1 DIABETES, RECRUITMENT, CHRONIC DISEASES, ADHESION, HYPERTENSION, ENDOTHELIAL DYSFUNCTION
Specific adhesion molecules such as VCAM-1, ICAM-1, and E-selectin are expressed on the surface of vascular endothelium and mediate in monocyte recruitment to the vessel wall. Plasma levels of these adhesion molecules help to predict the onset and prognosis of chronic diseases with an endothelial dysfunction component. In this sense, a longitudinal study on type 1 diabetes showed that higher levels of VCAM-1 (but not E-selectin or C-reactive protein) at baseline and through the 20-year follow-up period predicted the prevalence and incidence of hypertension [