QOL measurements
irritable bowel syndrome-quality, pain
Two instruments were used assessed the patient’s attitude toward her health status based on physical, psychological, and social aspects. We used the Short-Form 36 (SF-36) questionnaire for a general QOL evaluation based on eight domains: physical function, physical role, body pain, general health, vitality, social functioning, emotional role, and mental health. The questions were coded, summarized, and transformed to a scale from 0 (worst) to 100 (best) health statuses. Additionally, the questionnaire includes question about the change in the general health state. We also calculated physical (PCS) and mental (MCS) component summaries bases on an orthogonal approximation. This questionnaire has been validated in the Mexican [Specific QOL was assessed by the irritable bowel syndrome-quality of life (IBS-QOL) questionnaire [