2.2. Subjects
mental illness, sleep disorders, illness, fatigue, liver disease, malignant tumor, insomnia, allergies, mental disorders, depression, hepatitis, diabetes
THYROID DISEASE, ADRENAL DISEASE, OTHER METABOLIC DISEASE, LIVER DISEASE, BRAIN DISEASE, RENAL DISEASE, SLEEP APNEA SYNDROME, IMMUNOLOGICAL DISEASE, ALLERGIES, MALIGNANT TUMOR, CARDIAC DISEASE, HEPATITIS, DIABETES
After obtaining the consent of patients to participate in the study, the principal investigator enrolled subjects who met the selection criteria and were able to comply with the management procedures during the trial period.The selection criteria were Japanese males and females (1) aged between 60 and 75 years at the time of obtaining written consent, (2) with body mass indexes (BMIs) between 19 kg/mExclusion criteria included subjects who (1) had been instructed by a physician to refrain from walking or exercising; (2) were currently receiving medication or inpatient treatment for any serious illness; (3) were currently under the supervision of a physician for exercise or diet therapy; (4) could develop allergies to soybean, shrimp, crab, wheat, milk, egg, almond, squid, orange, cashew nut, kiwifruit, beef, sesame, salmon, mackerel, chicken, banana, pork, peach, yam, apple, or gelatin; (5) had a current or history of drug or alcohol dependence; (6) were currently visiting the hospital for mental disorders (e.g., depression) or sleep disorders (e.g., insomnia, sleep apnea syndrome, and so on), or had a history of mental illness; (7) were current smokers or had smoked in the past 3 months; (8) had irregular lifestyles due to night work or shift work; (9) had an extremely irregular lifestyle in terms of eating, sleeping, and so on; (10) were very fussy eaters; (11) had a weight fluctuation of ±5 kg or more within a 3-month period; (12) had knee surgery or leg problem and used a walking cane daily; (13) had a serious current or previous illness, such as brain disease, malignant tumor, immunological disease, diabetes, liver disease (e.g., hepatitis), renal disease, cardiac disease, thyroid disease, adrenal disease, or other metabolic disease; (14) had used (or was currently using) health foods, supplements, or medicines that affect muscle strength, walking function, or fatigue reduction in the past 3 months; (15) consumed or were currently consuming any health oil (e.g., coconut oil or MCT oil) that may enhance any of the dietary components being evaluated, retroactively, in the past 3 months; (16) had participated in other clinical trials within 3 months prior to the date of consent or have plans to participate in other clinical trials during the study period; (17) had donated more than 200 mL of blood within 1 month or more than 400 mL of blood within 3 months prior to the date of obtaining consent; (18) were currently pregnant or lactating, or may become pregnant or lactate during the study period; (19) had difficulty in complying with recording on various questionnaires; (20) were judged to be unsuitable as subjects based on clinical laboratory values and measurements at the time of screening; or (21) were judged by the investigator to be unsuitable as subjects.