3. Results
allergic
ADVERSE EVENTS, HYPERPIGMENTATION, GROUP B
A total of 72 subjects participated in the study and 60 (29 from Group A and 31 from Group B) participants completed the clinical trials. The remaining 12 patients dropped out for the following reasons: 2 participants from Group A withdrew due to adverse events including hyperpigmentation, allergic to herbs, or burning sensation in the skin, 5 subjects (1 from Group A and 4 from Group B) withdrew due to pregnancy, and 5 subjects (2 from Group A and 3 from Group B) withdrew before the end of the treatments due to personal reasons. In total, 130 stool samples were obtained from participants, of which 60 subjects provided 2 specimens before and after treatment, 10 subjects provided only pretreatment specimens, and the rest 2 subjects did not provide any samples.