Exploratory endpoints
atherosclerotic
PLAQUE
Lifestyle changes including diet, smoking habit and exercise will be captured using a questionnaire 24 months following enrolment. This will be used to determine whether the intervention compared to standard care results in changes to lifestyle or risk factors. To explore the pathophysiological mechanisms that influence cardiovascular risk, blood samples will be obtained and stored from consented participants, and we will perform visual and quantitative assessment of atherosclerotic plaque identified on CTCA imaging.