Funding
This study was supported by the Program of the China National Health Commission and National Medical Products Administration (NMPA), Grant No. CMR-20161129-1003; the National Defense Science and Technology Innovation Fund of China, Grant No. 19-163-00-KX-003-001-01; the National Natural Science Foundation of China, Grant No. 82072953, 81471308 and 81802819; the Liaoning Province Excellent Talent Program Project, Grant No. XLYC1902031; Top young talents of Liaoning Provincial Government, Grant No. XLYC1907009, and Dalian Science and Technology Innovation Fund, Grant No. 2018J11CY025.