Sample size
cancer
CANCER, PCP
We conservatively estimated the intra-class correlation coefficient (ICC) to be 0.30 based on our previous research [To account for additional planned sub-analyses and possible study withdrawal and/or loss to follow-up, we further inflated our sample size for a total of 20 patients per PCP (five cancer survivors and 15 general population patients) for a total sample size of 1,280 patients (320 cancer survivors and 960 general population patients). We planned to recruit a total of 30 patients per PCP to ensure our target sample size of 20 patients per PCP was met (five cancer survivors and 15 general population patients).