Study design
pain
HEAT
This experimental study was conducted as a randomized controlled trial in which healthy, pain-free participants were randomly divided (counterbalanced) into two intervention groups and one control group. Both intervention groups received either a hypoalgesic or a hyperalgesic suggestion related to the pattern of the subsequently applied heat pain within an OA paradigm. The control group received no suggestion. All participants received the identical information about the exact temperature course of the heat stimuli beforehand. In order to perform the suggestions as authentically as possible, a cover story was told to all participants at the beginning of the study. All participants were blinded to the true purpose of the study. The study was previously approved by the ethics committee of the University of Lübeck (file number: 21–028) and pre-registered in the Open Science Framework (