Objective
nutritional impairment, CFRD, fibrosis, diabetes
CATABOLIC STATE, FIBROSIS, DIABETES
Edited by: James Shaw, Newcastle University, United KingdomReviewed by: Claudia Piona, University City Hospital of Verona, Italy; Ayat Bashir, Newcastle University, United Kingdom; Angeles Maillo-Nieto, Newcastle upon Tyne Hospitals NHS Foundation Trust, United KingdomCystic fibrosis (CF)-related diabetes (CFRD) resulting from partial-to-complete insulin deficiency occurs in 40-50% of adults with CF. In people with CFRD, poor glycemic control leads to a catabolic state that may aggravate CF-induced nutritional impairment and loss of muscle mass. Sensor augmented pump (SAP) therapy may improve glycemic control as compared to multiple daily injection (MDI) therapy.