Statistical analysis
PAD, CAD, peripheral artery disease
PERIPHERAL ARTERY DISEASE, DIABETES MELLITUS, PAD, SECONDARY, HYPERTENSION, CAD
Baseline characteristics were reported as mean and standard deviation (SD) for normally distributed continuous variables, or median and interquartile range [IQR] for non-normally distributed continuous variables. Binary and categorical variables were reported as frequency and percentage.For the purpose of this analysis, we analyzed the interactions between sex and the effect of mAFA intervention on the primary and secondary outcomes, using Cox proportional hazard models. All the models were adjusted for age, type of AF, comorbidities (hypertension, diabetes mellitus, CAD, history of HF, history of IS, peripheral artery disease (PAD)), previous AF treatments, and cluster effect. Survival curves were also reported for the risk of the primary composite outcome according to mAFA allocation and sex.A two-sided 