2.3. Outcomes
cognitive dysfunction, throat, fatigue, shortness of breath
SECONDARY, SARS-COV-2 INFECTION
The primary outcome was the nucleic acid shedding time and post-COVID-19 condition. The secondary outcomes were days until negative swab test, days of first symptoms resolution, nucleic acid test negative rate within 3 days, negative rate within 5 days, and negative rate within 7 days.The nucleic acid shedding time was defined as the number of days from the first positive test to 2 consecutive negative nucleic acid results after enrolment. Days until negative swab test was defined as the time from the first positive COVID-19 nucleic acid test to the first negative throat swab test. Days of first symptoms resolution was defined as the number of days from the exact time of the patient first symptoms to the exact time of the disappearance of symptoms. Post-COVID-19 condition occurred in individuals with a history of probable or confirmed SARS-CoV-2 infection, usually 3 months from the onset, with symptoms that last for at least 2 months and could not be explained by an alternative diagnosis. Common symptoms included, but were not limited to, fatigue, shortness of breath, and cognitive dysfunction, and generally had an impact on daily functioning. Symptoms might be new onset following initial recovery from an acute COVID-19 episode or persist from the initial illness. Symptoms might also fluctuate or relapse over time.