Study participants
gingivitis
SYSTEMIC DISEASE, GINGIVITIS, DENTAL PLAQUE, WEST, CAVITY
This article is reported according to CONSORT guidelines for reporting randomized clinical trials. This study was approved by the Research Ethics Committee of West China Hospital of Stomatology (WCHSIRB-D-2020-309) and was in agreement with the Declaration of Helsinki and complied with Chinese Good Clinical Practice (GCP) regulations. All participants were recruited at the West China Hospital of Stomatology, Sichuan University, and signed informed consent. The trial was registered in the Chinese Clinical Trial Registry (The participants were aged 18–65 years with no systemic diseases. All participants had intact Ramfjord teeth (16, 21, 24, 36, 41, 44) in the oral cavity. Participants had gingivitis, with a modified gingival index ≥ 1, dental plaque index ≥ 1.5, and gingival sulcus depth < 3 mm [