Cytokine analysis
In an exploratory post-hoc analysis performed to assess the relative paucity of irAEs, we noted a statistically significant increase in plasma concentrations of six chemokines from baseline compared to both C1D1 and C2D15. These included known IFN-γ inducible chemokines CXCL9, CXCL10, and CXCL11 (Fig. 