Statistics
Associations for quantitative variables were determined by Spearman rank correlation method. Between-the-group comparisons were carried out by ANOVA/Kruskal–Wallis test for quantitative and order variables and exact Fisher test for binary and qualitative variables. The efficacy was evaluated using paired Wilcoxon test for quantitative indicators and McNemar’s binomial test for qualitative indicators. The differences were considered statistically significant at 