Immunogenicity
Among a total of 121 subjects who received at least one dose of efbemalenograstim alfa and had at least one immunogenicity data point, anti-efbemalenograstim alfa binding antibodies were detected in 11 (9.1%) subjects overall including 5 subjects positive only at baseline, 3 subjects positive at baseline and post-baseline but no treatment-boosted, and 3 subject treatment-emergent positive. No neutralizing antibodies to efbemalenograstim alfa or to G-CSF were detected.