T cell and cytokine responses after treatment
BLOOD
T cell and cytokine responses were analyzed from blood samples collected at baseline (prior to the study treatment on day 1) and on day 8. Blood samples collected on day 8 were obtained prior to the administration of dexamethasone, if applicable. Due to the administration of dexamethasone prior to blood sample collection on day 8, samples were not obtained from two patients in the control group, one in the demeclocycline 150 mg group, and two in the demeclocycline 300 mg group. Furthermore, a blood sample from one patient in the demeclocycline 300 mg group was not obtained due to patient withdrawal.The average change rates of CD8Changes in HLA-DRIn contrast to CD8An analysis of the relationship between the change rates of T cells (CD4Relationships between change rates of T cells and cytokines in demeclocycline treatment groups (n = 9). (