Kaplan-Meier Curves for Patients Who Received Anakinra Plus Standard of Care vs Patients Who Received Standard of Care Alone
REGRESSION
Graphs show time to mechanical ventilation until day 15 (A) and overall survival during follow-up (B). Patients were censored at the time of the last available follow-up if still alive for survival analysis. Unadjusted hazard ratios (HRs) with 95% CIs were estimated by Cox regression analyses.The proportion of patients requiring ICU admission up to day 15 did not differ between the groups (RR, 0.96; 95% CI, 0.48-1.95) (By day 28, 4 patients in the anakinra group had died, vs 5 patients in the SoC group (RR, 0.77; 95% CI, 0.21-2.77; The sensitivity analysis assessing the possible bias due to lost to follow-up patients on the primary outcome (eTable 6 in 