Statistical analysis
noncancerous lesions, ESCCs
ADVERSE EVENTS, SECONDARY
The primary outcomes were the diagnostic accuracies of the AI system and endoscopists. The secondary outcomes were sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and adverse events. These parameters were calculated as follows: accuracy = correctly diagnosed lesions/total target lesions; sensitivity = correctly diagnosed ESCCs/total ESCCs; specificity = correctly diagnosed noncancerous lesions/total noncancerous lesions; PPV = correctly diagnosed ESCCs/total lesions diagnosed as ESCC; NPV = correctly diagnosed noncancerous lesions/total lesions diagnosed as noncancerous lesions. The results are shown with 95% CIs. All analyses were performed on a personal computer using the EZR software package, version 1.55 (Saitama Medical Center, Jichi Medical University, Tochigi, Japan) [