5. Conclusions
The present study found a significant increase in the RMR after co-administration of 200 mcg of selenium L-selenomethionine and 25 mg of Zn gluconate, with the thyroid function hormones remaining unaffected. Furthermore, significant improvements in Se status and TUG performance were detected in the supplementation group compared to the placebo group. However, despite the larger improvements in body composition, cardiorespiratory fitness, and most of the remaining functional capacity outcomes of the intervention group, no time × group effect was found. Finally, even though the duration of the intervention, the dosages, and the forms of Se and Zn supplements used in the present study were effective, more research is needed to reveal the most effective combinations of the two micronutrients. 