Immunological biomarker studies
PanCancer
Peripheral blood samples were collected for immune profiling by multicolour flow cytometry and NanoString® gene expression analysis with a focus on NK cells based on prior preclinical studies [Maintenance of NK cell subsets in patients after NMP treatment. Flow cytometry analysis of PBMC from 10 patients collected pre-treatment (PRE) and after cycles 2–3 (POST) of NMP therapy. Gene expression immune profiling for abundance and function of immune cell subsets. The NanoString PanCancer Immune Profiling Panel V1 was used to analyse samples collected at pre-treatment (PRE), C1D21 and C4D1. The relative abundance of 