Findings
T1D, atrophy
ATROPHY, ALZHEIMER DISEASE
In this cohort study of 416 adults with T1D and 99 controls, participants with T1D had higher brain age values compared with controls, while Alzheimer disease–like regional atrophy was comparable between the 2 groups. Greater neuroimaging signs of brain aging were associated with lower psychomotor and mental efficiency among participants with T1D.