Single ascending dose study and food effect study
Data collected from the participants were included in the PK and statistical analyses. The actual time of sample collection was used for statistical calculations. The mean TQA3526 plasma concentration-time profiles after a single dose are shown in Mean (±Plasma pharmacokinetic parameters in the single ascending dose study.Data are expressed as mean ± In the food effect study, the mean total exposures were higher under the fed condition with a geometric LSM ratio (90% CI) of 122.10% (113.41%–131.45%), indicating that food intake could increase bioavailability. In addition, The 