Statistical analysis
Statistical analyses were performed using the Number Cruncher Statistical System (NCSS) 2017 Statistical Software (Utah, USA) package program. In addition to descriptive statistical methods (mean, standard deviation) in the evaluation of the data, the distribution of the variables was examined with the Shapiro–Wilk normality test, one-way analysis of variance, for the comparison of the normally distributed variable and independent t-test for the comparison of the paired groups. The Kruskal–Wallis test was used for intergroup comparison of non-normally distributed variables, Mann–Whitney U test was used for pairwise comparisons, and chi-square test was used for qualitative data comparisons. Kaplan–Meier analysis and log-rank test were used to determine the survival of the groups. The results were evaluated at a significance level of p < 0.05.