Author contributions
JP
JP and AH conceived the study, designed the trial, obtained grant funding, and oversaw management of the trial. LG, DQ, JG and SL helped in designing parts of the study and participated in the implementation of the study. LG performed the data analysis with the help of AL, BS and DQ. All authors (LG, DQ, AA, AH, and JP) were involved in the interpretation of data. LG and DQ wrote the draft manuscript. Authors LG, DQ, SS, JG, AA, AH, AL, SL, BS and JP revised the manuscript for important intellectual content and gave final approval for the version to be published. JP and AH supervised all the work. All authors contributed to the article and approved the submitted version.