Randomization and Masking
asthma
ASTHMA, RECRUITMENT, ASTHMA
The nurse practitioner of our clinical research unit randomized the patients in a 1:1 ratio to the WAP group or DAP+WAP group within 1 week after inclusion by connecting to a centralized web-based system. Randomization was performed in permuted blocks of randomly varying sizes with stratification based on age (children vs adults), recruitment site (hospital vs office), and the GINA asthma control score during the previous month. Participant blinding was not feasible. Group assignment was known to the participants and the clinical research unit but not to the trial investigators until the next follow-up visit with the patient.Asthma control was categorized as reflecting controlled, partially controlled, or uncontrolled asthma (score of 0, 1 or 2, or 3 or 4, respectively) as proposed by the GINA [