Summary Statistics of Baseline Measures Overall and Stratified by Treatment Group
hemothorax, opacification, chest pain, Infection
RENAL, PLEURAL INFECTION, HEMOTHORAX, INFECTION
Abbreviations: CPI, complicated pleural infection; IPFT, intrapleural fibrinolytic therapy; RAPID, Renal, Age, Purulence, Infection Source, and Dietary Factors.Unless otherwise indicated, data are expressed as No. (%) of patients. Percentages have been rounded and may not total 100.Calculated as weight in kilograms divided by height in meters squared.In those patients randomized to IPFT, 6 (60%) had 6 doses, 2 (20%) had 5 doses, and 2 (20%) had 4 doses. One patient who received 4 doses refused further IPFT due to chest pain and requested surgery. This patient underwent crossover treatment and received a VATS decortication. The other patient who received 4 doses had a hemothorax, IPFT was stopped, and the hemothorax was monitored. The patient’s CPI ultimately resolved with no further treatment. In those patients randomized to surgery, all patients received a VATS decortication.On protocol image 2 following completion of treatment, 5 patients (50%) in the IPFT group and 3 (30%) in the surgery group had greater than 75% opacification improvement (