2.5. Outcome Measures
DRUG INTERACTIONS
The mean changes between admission and discharge were measured in the number of regular medications (as-needed medicines were not included, and combination products were included as one drug), STOPPFrail criteria, total drug–drug interactions, DBI, and MRCI. Any decrease in the pharmacotherapeutic variables studied during hospital admission was considered an optimization of the pharmacotherapy.Likewise, the change in the 28-day cost of prescriptions in € was estimated between admission and discharge.