Subjective measures
SE
SECONDARY
Product-liking scores at given times for Vuse Vibe and Vuse Ciro were consistently between those for usual brand cigarettes, which had the highest scores, and nicotine gum, which had the lowest scores (Table Statistical comparisons of subjective measures parameters between Vuse Vibe or Vuse Ciro and the high- and low-AL comparators.Least squares means from mixed-effect models are presented. 1 = statistically significant different from UB cigarette; 2 = statistically significant different from nicotine gum. The statistical significance thresholds were 0.0013 for the primary endpoints (*) and 0.05 for the secondary endpoints (all others). Vuse ENDS use suppressed the urge to smoke in the first fifteen minutes after initiation of product use to a greater degree than nicotine gum but to a lesser degree than UB cigarettes (Fig. Arithmetic mean (SE) urge to smoke response profiles over four hours after initiation of product use. SE standard error, UB usual brand.