Acknowledgements
This work was supported by the National Natural Science Foundation of China (81930024, 82071003, 82000879), the National Key R&D Program of China (2018YFC1106100, 2018YFC1106101), the Research Grant of the Shanghai Science and Technology Committee (20DZ2270800), the Sample Database Project of Shanghai Ninth People's Hospital (YBKB201901), and the Joint Innovation Team for Young Physicians of Shanghai Ninth People's Hospital (QC202002).