3. Discussion
osseous venous stasis, Pain
COLD, DYSFUNCTION, ADHESION, HEAT, HYPERTENSION, DISEASES
CP is one of the common diseases of knee joint. Pain and dysfunction caused by CP severely decreases the quality of life of patients. Currently, the diagnostic standard of CP has not yet formed a unified consensus. There is no effective cure for the treatment of CP, and the effects of surgical treatment which are widely used in clinic, such as cartilage transplantation and total knee replacement, is not superior o non-surgical treatment.At present, MT is one widely used conservative treatment for patients with CP. Manipulative therapy can promote blood circulation and accelerate metabolism, mainly through the following mechanisms to achieve the purpose of treatment: increase the local nutrient supply, and strengthen the “pumping effect” of cartilage tissue itself, which is conducive to the self-repair of the articular cartilage. Eliminate local intra osseous venous stasis, reduce intra ossseous hypertension, and promote absorption of local inflammatory tissue. Exogenous cold pathogen is one of the causes of CP, manipulative treatment can generate heat and disperse cold, and promote local Qi and blood circulation. Promote the mechanical balance of the knee joint, release the adhesion, and improve the stability and functional state of the knee joint.As far as we know, there has been no standard large-sample clinical study on MT in the treatment of CP, although increasing studies have found that MT has a statistically significant effect on alleviating symptoms of CP with a well-established safety profile. We intend to evaluate its efficacy and safety in a prospective randomized controlled study.