Statistics
DISEASE, DISEASES
In lieu of anticipating that relatively few patients with each condition would be enrolled, no formal statistical tests were planned. Instead, descriptive summaries and data listings were planned to summarize the results.Continuous data were summarized in terms of the mean, standard deviation (SD), minimum, maximum, median, and number of observations; categorical data were summarized as frequency counts and percentages. Although the efficacy population set included all enrolled patients who had at least 1 dose of baricitinib, efficacy analyses were divided among diagnosis-specific efficacy population subsets.Mean DDS was calculated from the average scores of 7 days preceding the current visit; however, if more than 50% symptom scores were missing, the mean DDS was not calculated. A last-observation-carried-forward imputation replaced missing data with the most recent non-missing postbaseline assessment. Proportion of days meeting threshold was calculated by the total number of days meeting the threshold divided by total number of days with non-missing diary scores during the interval. Mean DDS with < 0.5 was used as a threshold for all diseases as an indication of disease control. All corticosteroid doses were standardized to an equivalent prednisone dose.