Introduction
obesity, T2D, inflammation, CVD, adiposity, T2D a LCD
OBESITY, CARDIOVASCULAR DISEASE, CVD, INFLAMMATION, ADIPOSITY, EVENTS, TYPE 2 DIABETES, ENDOTHELIAL DYSFUNCTION
One of the major causes of mortality in type 2 diabetes (T2D) is cardiovascular disease (CVD) [T2D management includes lifestyle changes involving both diet and physical activity and is important to improve glycemic control and decrease risk of CVD [Along with endothelial dysfunction, circulating markers of low-grade inflammation such as hsCRP and IL-6 are often elevated in obesity and T2D and associated with a higher risk of cardiovascular events [Previously, we reported that in patients with T2D a LCD high in fat for 6 months reduced HbA1c, weight and abdominal adiposity compared to a control diet, while blood pressure and lipid levels were unaffected [