Patients
During the study, 90 patients who met the inclusion criteria participated in the study. The patients aged between 41 to 77 years and were divided into two groups of drug and placebo. Because of irregular consumption or usage of similar products, 20 patients were excluded from the study. So, 70 patients completed the research including 33 and 37 patients in drug and placebo groups, respectively (Fig. Flowchart of enrollment and allocation of participants and study designBaseline demographic and clinical characteristics of study patients