Discussion
obesity
OBESITY
In this study, subgroup analyses implied that patients at advanced maternal age (35-43 years old) or obese/overweight women (BMI 24-30) may benefit from ZYP treatment, as their rates of implantation and pregnancy outcomes were significantly increased in the ZYP group.AMA patients are more likely to seek the help of ART due to declined fecundity, while treatment outcomes are considered inferior to those of non-advanced age patients (As the obesity epidemic is on the rise, the resulting decline in female fecundity poses another social problem (There are various strengths in the current study. At first, the original cohort was a randomized, double blinded, placebo controlled and multicenter design. A long follow-up period enabled the collection of live birth outcomes and neonatal information. Due to the large sample size and long follow-up period of the RCT, the current subpopulation analysis provided a broad range of information. It should also be noted that after stratification, the baseline characteristics are still well balanced, making the two arms comparable (The main limitation is that the current research is a 