Introduction
primary infection, infection, deaths, reinfection
PRIMARY INFECTION, PERTUSSIS, INFECTIOUS DISEASE, INFECTION, REINFECTION
The introduction of vaccines has significantly reduced the amount of infectious disease–related deaths (Data on humans in the pre–pertussis vaccine era indicated that although natural infection does not result in complete lifelong protection, reinfection is much milder than primary infection (Currently, modifications of existing pertussis vaccines as well as new vaccine candidates are being investigated (In 2017, a human challenge model for In this exploratory study, we monitored the cellular kinetics in humans after intranasal challenge with 