Author contributions
CM, HT
RECRUITMENT
PW: conception and design of the study, patient recruitment, interpretation of the results revising the manuscript. JUB: patient recruitment, conception and design of the GeparX study. PK: patient recruitment. TL: patient recruitment, interpretation of the results, revising the manuscript. MJ: patient recruitment. BVS: patient recruitment. ES: patient recruitment. CS: conception and design of the GeparX study, patient recruitment. TF: patient recruitment. CD: conception and design of the GeparX study, acquisition of data and to the analysis/interpretation of the results. CK patient recruitment. KR: conception and design of the GeparX study. HT: patient recruitment. SK: patient recruitment. AP: patient recruitment, performance of analytical bone marrow aspirations for DTC-analysis. OS: patient recruitment. CM: patient recruitment, performance of analytical bone marrow aspirations for DTC-analysis. JDK: contribution to the experimental work for DTC-analysis, acquisition of data and to the analysis/interpretation of the results, drafting and revising the manuscript. VN: statistician of the the GeparX study, analysis/interpretation of the results. SL: conception and design of the GeparX study, interpretation of the results. All authors read, revised and approved the final version of the manuscript.