Clinical efficacy
PD, SD
A total of 386 cycles were administered to 128 patients, with a median of 3 cycles per patient (range 2–6). All patients had completed evaluation for efficacy. No one achieved CR. In the control group, 16 patients had PR, 16 patients had SD and 30 patients showed PD, the ORR was 25.81%, and the DCR was 51.60%. In the experiment group, 18 patients had PR, 24 patients had SD, and 24 patients showed PD, the ORR was 27.27%, and the DCR was 63.64%. The two groups showed no significant differences (Clinical efficacy of two groups (In subgroup analysis, in the second‐line treatments, the ORR of control and experiment group were 28.13% and 32.35%, and DCR were 53.13% and 79.41%, respectively. There were significant differences in DCR between the two groups (