Exploratory Outcomes
first-episode, schizophrenia
The difference in percentage PANSS score change between those with first-episode and relapsed schizophrenia in the MPGT group was not statistically significant, indicating a similar therapeutic effect of MPGT on both first-episode and relapsed schizophrenia (We found lower chlorpromazine equivalents were assigned to patients in the MPGT group than the TAU group throughout the study, though not statistically significant at the end of week 6 and week 12. MMRM of metabolic profile analysis showed no significant difference in lipid and glucose metabolism between treatment groups, but plasma prolactin levels were lower in the MPGT group (eTable 10 in 