Silent period is affected by antimuscarinic activity during unfatigued voluntary contractions
voluntary muscle contractions
CONTRACTION, CONTRACTIONS
The current study revealed that SP duration shortened during voluntary muscle contractions, where the duration of TMS-evoked SP progressively reduced with an increase in contraction intensity. The relationship between SP and contraction intensity has been reported on a number of occasions, where many studies report that SP duration is unaffected by voluntary contractions (Haug et al. The initial 50–80 ms of the TMS-evoked SP has been linked to spinal mechanisms such as recurrent inhibition, after-hyperpolarization of activated motoneurons, and activation of 1a inhibitory interneurons (Duchateau and Baudry The lengthening of SP due to promethazine contrasts with two previous TMS studies exploring anticholinergic effects in the CNS. However, there are a number of factors that differ between previous studies and the current investigation. The study of Di Lazzaro (Di Lazzaro et al. 