Abstract
HIV exhibit immune dysfunction
CHRONIC INFLAMMATION
The anti‐diabetic drug metformin may promote healthy aging. However, few clinical trials of metformin assessing biomarkers of aging have been completed. In this communication, we retrospectively examined the effect of metformin on epigenetic age using principal component (PC)‐based epigenetic clocks, mitotic clocks, and pace of aging in peripheral monocytes and CD8People living with HIV exhibit immune dysfunction, chronic inflammation, and heightened signs of biological aging captured by epigenetic clocks. Here, we performed a post hoc cell‐type specific epigenetic age analysis of monocytes and CD8
