AUTHOR CONTRIBUTIONS
Hidenori
Haruko Tobata, Hirohisa Suido, and Toru Eguchi conceived the idea of the study. Ai Fujimoto, Kana Fujii, Haruko Tobata, and Hirohisa Suido developed the statistical analysis plan and Ai Fujimoto conducted statistical analyses. Hidenori Suzuki, Naoko Miyake, Hisae Fukuike, and Kana Fujii contributed to collect the clinical data and interpretation of the results. Ai Fujimoto, Toru Eguchi, and Haruko Tobata contributed to the interpretation of the bacteriological results. Ai Fujimoto and Kana Fujii drafted the original manuscript. Haruko Tobata supervised the conduct of this study. All authors reviewed the manuscript draft and revised it critically on intellectual content. All authors approved the final version of the manuscript to be published.