Conclusion
AKI, critically ill
CRITICALLY ILL
Higher protein dose, compared to usual dose, is associated with worse clinical outcomes in mechanically ventilated, critically ill patients with AKI. No effect of either higher or lower protein dosing was observed in patients with AKI who received KRT. Based on these findings, current guidelines for nutrition support in critically ill patients with AKI should be carefully re-evaluated and further research is warranted.