Study product use period completion
enema
HIV INFECTION
A study product use period was considered completed if the participant received the study product and completed the scheduled study product use period. Study product use period completion rates were 94% for the insert, 95% for the suppository, and 95% for the enema. Among enrolled participants, 92% exited the study at their scheduled end of study visit. Reasons for early study terminations included “Participant refused further participation” [n = 2 (1%)], “Participant is unwilling/unable to comply with required procedures” [n = 6 (3%)], “Lost to follow-up” [n = 4 (2%)], “Investigator decision” [n = 1 (<1%)], “Unable to contact participant” [n = 3 (1%)], “HIV infection” [n = 1 (<1%)], and “Other, specify” [n = 1 (<1%), participant relocating].The per-protocol subset of participants (those who completed all three study product use periods) included 202 (93%) out of the 217 participants enrolled (see 