References
HT
Mean plasma concentration profile of main HT metabolites before (0 h) and after intake of IP-1 (Mean urinary excretion of main HT metabolites quantified before (0 h) and after intake of the investigational products. Blue lines: IP-1 (Typical nutritional value of the food supplements, and content of hydroxytyrosol (HT) and derivatives (as free forms) in the food supplements used for the trial. Ole: oleuropein, HVA: homovanillic acid, DOPAC: 3,4-dihydroxyphenylacetic acid. n.d.: not detectable; *: according to producer.Mass transitions of hydroxytyrosol and its metabolites. HT: hydroxytyrosol, Ole: oleuropein, DOPAC: 3,4-dihydroxyphenylacetic acid, HVA: homovanillic acid, HT-S: hydroxytyrosol sulphates, HT-G: hydroxytyrosol glucuronides.Limit of quantification of HT and its metabolites in plasma and urine. Results are expressed as mean (in mg/L) ± SEM.Pharmacokinetic parameters from plasma concentration. CMean cumulative (0–12 h) excretion of HT metabolites (micromoles) ± SEM in urine. Significance vs. EVOO was as follows: *: significant at 