Segmentation and radiomic feature extraction
multiple lesions, tumors, NII
TUMORS
All targeted tumors were manually delineated slice by slice by one author with 5 years of experience with chest CT interpretation using the medical image processing and navigation software 3D Slicer (version 4.10.1, Brigham and Women’s Hospital). Patients with multiple lesions on their CT scan had the lesion with the largest diameter selected. Volumes of interests (VOIs) were then confirmed by another radiologist with 10 years of experience with chest CT interpretation. Images and VOIs were exported in the NII format for further analysis. Prior to radiomic feature extraction, the voxel size of the VOI was resampled to 1*1*1 mm