In vivo skin irritation test
edema, erythema
SLS, ERYTHEMA, EDEMA
After fin chamber removal for 1 h, a slight erythema was shown at an area of 2% SLS among most of the volunteers. On the other hand, no erythema or edema was not observed in areas of CE and CB. PII values of bare skin, 2% SLS, CE, and CB were 0.05, 0.70, 0, and 0.01, respectively. This finding could confirm a good safety profile of these two formulations for human skin.