Blood sample collection
Tumour necrosis
BLOOD, TUMOUR NECROSIS
Blood samples were collected from a venepuncture in the antecubital fossa before 8am after an overnight fast for all participants. Blood samples were collected at baseline (3 days prior to FMNST) before medication was disposed, 1 day after FMNST, and 7 days after FMNST. Blood samples were processed and analysed by the ISO-certified laboratory at the University São Leopoldo—MANDIC (Campinas, Brazil) by an operator blinded to group allocation. Full blood count, high-sensitivity C-reactive protein (CRP), interleukin-6 (IL-6), basal insulin, glucose, erythrocyte sedimentation rate (ESR), Fibrinogen, and Tumour necrosis factor-α (TNF- α), were measured following standard laboratory procedures.