Drop comfort (ITT population)
stinging
Drop comfort was assessed for each eye immediately and at 1 and 2 min following initial dosing using the Ora Calibra Drop Comfort Scale at baseline. Descriptions of drop comfort using the Ora Calibra Drop Comfort Scale were assessed at 3 min after initial dosing. On this questionnaire, patients were asked to choose 3 words that best described how each eye drop felt in both of their eyes. The positive responses were comfortable, cool, refreshing, smooth, and soothing. The negative responses included burning, filmy, stinging, sticky, thick, gritty, and irritating. Patients may have also selected “other” and written in a different response, which may have been either positive or a negative.Responses to the Ora Calibra Drop Comfort Scale at baseline between the treatment groups were comparable, with 67 (83.8%) patients in the PL9643 group and 66 (82.5%) patients in the placebo group reporting ≥1 positive response and 31 (38.8%) patients in the PL9643 group and 29 (36.6%) patients in the placebo group reporting ≥1 negative response. The most common positive responses in the PL9643 group were “cool” and “refreshing” (