Background
respiratory depression, disorders of pancreaticobiliary pathologies
ADVERSE EVENTS, EVENTS, RESPIRATORY DEPRESSION
Endoscopic retrograde cholangiopancreatography (ERCP) is a common procedure employed to diagnose and treat disorders of pancreaticobiliary pathologies [Propofol is the most commonly used hypnotic agent in sedation during endoscopic procedures for its advantages of fast onset and quick recovery. However, propofol may cause respiratory depression and cardiovascular events, which are easier to appear in cases of old age and high-speed administration of propofol [Magnesium is a non-specific calcium channel inhibitor and a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, which has analgesic and mild sedative properties [We hypothesized that the antinociceptive, anesthetic and central sedative effects of magnesium might be beneficial in elderly patients undergoing ERCP procedures. This prospective study was designed to evaluate the effects of intravenous magnesium administered as adjuvant to propofol during ERCP on propofol consumption and peri-procedural adverse events.