Data mining and statistics
Kock’s pouch
Descriptive statistics were calculated for age, BMI and gender (Supplementary Table SIntervention effects on SCFA and GI permeability were assessed by mixed model analysis on baseline-corrected data. A Following removal of the biological outlier (Kock’s pouch subject; see “Multivariate association with linear models (MaAsLin2) analysis with default setting was used for the association of PDB with bacterial pathways. Differential expression and abundance analysis were performed by Empirical Analysis of Digital Gene Expression (EdgeR) [