Participant Demographic and Clinical Characteristics at Baseline
depressive disorder, depressive, MDD, depression, Depression
Abbreviations: ADT, antidepressant treatment; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); HAMD-17, 17-item Hamilton Rating Scale for Depression; MADRS, the Montgomery-Åsberg Depression Rating Scale; MDD, major depressive disorder; SNRIs, serotonin and norepinephrine reuptake inhibitors; SSRIs, selective serotonin reuptake inhibitors; VAS, Visual Analogue Scale score.Two patients were included in other ethnicities: 1 identified as Hui ethnicity, and the other identified as Man ethnicity.One patient was receiving a norepinephrine–dopamine reuptake inhibitor (bupropion), and the other was receiving a noradrenergic and specific serotonergic antidepressant (mirtazapine).Range, 0 to 52; higher total score indicates more severe depression.Range, 0 to 60; higher score indicates more severe depressive symptoms.Range, 0 to 10. A score of 0 indicates “Seeing my normal state as a reference, my state is horrible during this period”; 10, “Seeing my normal state as a reference, my state is quite good (close to my normal state)” during this period. VAS-1 was “How did you feel about your state during the period when your condition was stable, under the treatment of your current medication?”; VAS-2 was “How do you feel about your state during the recent period when you are not feeling well, under the treatment of your current medication?”