Study population
CRITICAL ILLNESS
This prospective, single-center, randomized clinical trial was conducted at The First Medical Center of Chinese PLA General Hospital. The study protocol was approved by the local Ethics Committee and was registered at Chinese Clinical Trial Registry. Written informed consent was obtained from each patient diagnosed with a critical illness requiring CVC between October 2022 and March 2023. A flow diagram of the study is shown in Fig. CONSORT flow diagram of the study