1. Introduction
DRY EYE, INFLAMMATION, DISEASE, OXIDATIVE STRESS
Due to the rising demand for supplements targeting cognitive enhancement and dry eye together with the health benefits of anthocyanins, we have developed a functional soup containing an anthocyanin-rich functional ingredient, or “Anthaplex,” and assessed the effects on cognitive function and eye dryness together with the possible mechanisms. A total of 69 male and female health volunteers were randomized and divided into placebo, D2, and D4 groups. All subjects consumed 120 mL of placebo or functional soup containing “Anthaplex” either at 2 or 4 g per serving per day within 5 min in the morning for eight weeks. The cognitive function, working memory, dry eye, AChE, MAO, MAO-A, MAO-B, and GABA-T activities, BDNF, HAC, HDAC, and DNMT activities, pH, and amount of lactic acid-producing bacteria, particularly The global market of functional foods targeting wellness promotion, disease risk reduction, and quality of life promotion has been increasing around 8% [It has been revealed that anthocyanin-rich substances improve cognitive function by improving the dynamic balance of neurotransmitters, oxidative stress, inflammation, apoptosis, and signal transduction [“Anthaplex” is a novel functional ingredient consisting of the extracts of purple waxy corn (