Introduction
ventilator-induced lung injury, breathing is esophageal manometry, ARDS
ARDS, ACUTE RESPIRATORY DISTRESS SYNDROME
Controlled mechanical ventilation with minimal patient effort has been a strategy to minimize the risk for ventilator-induced lung injury in patients with acute respiratory distress syndrome (ARDS) [The gold standard method to estimate patient effort of breathing is esophageal manometry, which estimates pleural pressure, but has several limitations. Esophageal manometry is invasive, requires a special catheter, and requires expertise for appropriate catheter placement, calibration, and interpretation [There are almost no data about the accuracy of any of these maneuvers in children, which is particularly important given substantial differences across the pediatric age spectrum with respect to chest wall elastance, airway resistance, and control of respiratory drive..