Conclusion
orthodontic, tooth
A twice-daily use of an enzyme-containing mouthwash decreased the amount of dental biofilm in adolescents with fixed orthodontic appliances over an 8-day period without significantly affecting the composition of the salivary microbiome. The results of this pilot study indicate that the mouthwash, when applied in adjunct to regular tooth brushing, may be beneficial for adolescent orthodontic patients and justify a larger clinical trial with the prolonged duration.