End points
SECONDARY
The primary end-point was the success rate of induction of general anesthesia produced by the initial bolus dose, i.e. the percentage of patients who achieved successful induction after the initial bolus dose, without requiring a top-up dose.The secondary end-points were: (1) the time to reach a MOAA/S ≤ 1, defined as the time from the first administration of ciprofol or propofol to the first occurrence of MOAA/S ≤ 1; (2) the time for loss of the eyelash reflex, defined as the time from the first administration of ciprofol or propofol to disappearance of the eyelash reflex; (3) emergence time, defined as the time from the completion of surgery to the first occurrence of MOAA/S = 5; (4) number of top-up doses; (5) incidence and severity of AEs during the whole study, number of corresponding treatments, and the accumulated doses of rescue medication for AEs within 15 min after the initiation of induction.