Ethics approval and consent to participate
Ethical approvals for the trial were obtained from the Research Ethics Committees of the London School of Hygiene & Tropical Medicine (Reference number 26770) and the Comité National d’Ethique pour la Recherche en Santé (CNERS) in Senegal (Reference number 0000111/MSAS/CNERS/SP). Written informed consent was obtained from parents and caregivers of the study children. For children aged ≥ 12 years, positive written assent was obtained in addition to the parental consent.