Safety
TEAEs
In Part A, four Japanese adults reported TEAEs: one (11.1%) each in the zuranolone 10‐mg and placebo groups, and two (22.2%) in the zuranolone 30‐mg group (Table Overall summary and incidence of TEAEs (Parts A and C) (safety analysis population).
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BP, blood pressure; MedDRA, Medical Dictionary for Regulatory Activities; mg, milligram; 3‐way crossover design. Subjects were randomized into one of three groups based on a 3 × 3 Latin square design to receive zuranolone 10 mg, zuranolone 30 mg, or placebo.