References
REGRESSION
Flowchart of inclusion of the PROMISS microbiota ancillary study.Microbiota alpha-diversity from baseline (BL) to follow-up (FU) in the high protein compared to control group, based on the Shannon index and the Simpson index. Asterisk indicates Multi-dimensional scaling plot of microbiota beta-diversity based on Bray–Curtis dissimilarity for baseline and follow-up visits in the high protein and control groups. Each point indicates one sample from one participant. The larger points depict the centroids. The axis depicts 14.1% and 10.1% of variation in Bray–Curtis dissimilarity in the study population. The closer the points to each other, the more similar the microbial composition. Baseline (BL) and follow-up (FU) samples from the same participants are linked by arrows.Baseline characteristics of microbiota subsamples.BMI: Body mass index; MMSE: mini-mental state exam; aBW: adjusted body weight. Values are depicted as mean ± standard deviation (parametric continuous), median (interquartile range) (non-parametric continuous), or number (%) (categorical). Baseline differences between groups were tested via the independent sample Intervention effect on self-reported oral health.Shown are the numbers (and percentages) and odds ratios (95% confidence intervals). Differences between groups were tested with logistic regression for follow-up values, adjusted for baseline.