Study area and subjects
HIGH RISK PREGNANCIES, SECONDARY, HYPERCALCAEMIA
We used observational Se biomarker data collected as part of double-blinded, dose-varying, placebo-controlled, randomised trial of the effect of maternal vitamin DExclusion criteria included high risk pregnancies, women who had pre-existing medical conditions or those who were taking medications that could put them at risk of vitamin D sensitivity, altered vitamin D metabolism and hypercalcaemia. Additional details are provided elsewhereInclusion of participant samples for this secondary analysis was based on availability of at least one measurement of Se and/or selenoproteins at delivery in mothers or in VC blood of neonates. Infants for whom length and weight were not measured at birth or 12 months were excluded.Se was measured as part of a panel of metals and minerals for which the primary study intent was to examine effects of vitamin D supplementation on heavy metal concentrations