Introduction
depression, Depression
Depression has a lifetime prevalence of 10.8% worldwide.To widen access, cognitive behavioral therapy self-help (CBT-SH) supported by a trained practitioner is recommended in the treatment of mild to moderate depression in national treatment guidelines.Mindfulness-based cognitive therapy (MBCT) is an in-person group program recommended in national treatment guidelines for depression.Practitioner-supported MBCT-SH is one solution to widen access. MBCT-SH overcomes the barrier of fixed group session times, enabling people with inflexible work or domestic commitments to engage at a convenient time and place. Evidence is emerging supporting the potential of MBCT-SH for depression. A randomized clinical trial (RCT) with students found that unsupported-MBCT-SH was superior compared with waitlist in reducing depression symptom severity,We report findings from an RCT examining the clinical and cost-effectiveness of practitioner-supported MBCT-SH compared with practitioner-supported CBT-SH for adults experiencing mild to moderate depression. The prespecified primary hypothesis