Statistical analysis
recrudescence, re-infections
REINFECTION, POSTERIOR
Data were recorded using the WHO-standard template using the ODK (Open Data Kit) system on an Android tablet and added to the database in real time. Data cleaning was done regularly to identify and fix any data that were incorrect, inaccurate, or incomplete. Statistical analysis was performed using RStudio version 4.2.2 (The R Foundation for Statistical Computing).The primary endpoint was 28-day PCR-corrected treatment efficacy. Treatment outcomes were assessed according to the WHO guidelines [Descriptive analysis was conducted using frequency/percentage for qualitative variables and median/interquartile interval (IIQ) for quantitative variables. Categorical variables were compared with the The PCR-corrected per-protocol population consisted of all patients without a major protocol deviation, who had a primary endpoint at day 28, who did not have any reinfection. For Kaplan–Meier cumulative efficacy estimates, re-infections, lost to follow-up, and patients who withdrew were censored on the day of re-infection or the last day of follow-up. Posterior sampling was used to generate the PCR-corrected Kaplan–Meier estimates and 95% confidence intervals using the posterior probabilities of recrudescence.