Secondary objectives
bleeding, extrahepatic biliary complications
EVENTS, BLEEDING, COLD
To assess the impact of HOPE on the following features compared to simple cold static storage:
Quality of conservationIschemia–reperfusion injuriesIntra-operative events (bleeding, post-reperfusion syndrome)Postoperative outcomes (liver function tests not included in the definition of EAD, kidney function tests)90-day morbidity and mortalityLength of hospital stay and intermediate care unit stayIntra- and extrahepatic biliary complications within the first year after liver transplantationMid-term outcome (3-month and 1-year patient survival and graft survival)Costs of liver transplantation with ECD graft using HOPE or notTo perform cost-effectiveness analysis.