Introduction
otosinopulmonary and skin infections, myelokathexis, hypogammaglobulinemia, infections, lymphopenia, WHIM) syndrome
SEVERE CONGENITAL NEUTROPENIA, MYELOKATHEXIS, HYPOGAMMAGLOBULINEMIA, INFECTIONS, WARTS, LYMPHOPENIA, WARTS
Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome presents in childhood, with severe congenital neutropenia (SCN), lymphopenia, hypogammaglobulinemia, recurrent otosinopulmonary and skin infections, and warts. Warts and hypogammaglobulinemia are incompletely penetrant, and additional uncommon phenotypes continue to be discovered (Current treatments include granulocyte CSF (G-CSF), the standard of care for SCN (