Efficacy assessment
The primary endpoint was the DSN in cycle 1. DSN was defined as the number of days in which the subject had an ANC < 0.5 × 10Secondary endpoints included the DSN in cycles 2, 3, and 4, the time in days to ANC recovery post nadir (recovery defined as an ANC ≥ 2.0 × 10temperature of > 38.0 °C [100.4 °F] sustained for > 1 h and ANC < 0.5 × 10