2.4. Experimental Design
PD, anxiety
CORTEX
A cross-over randomized control trial (RCT) will be adopted to investigate the acute effect of the MSK program for PD on anxiety, selected kinematic and kinetic parameters, and frontal cortex hemodynamic responses during gait initiation and during steady-state walking in people with PD, under the following conditions: (a) a synchronous learning format and (b) an asynchronous remote video-based format.Volunteers will be asked to attend both conditions in a randomized order, separated by a washing-out period of at least one week. Levels of anxiety, kinematic, and DLPFC hemodynamic activity data will be collected before and after the two different interventions, which will last for approximately 45 min. The control situation will be defined based on the data collection at the same time points as above, but without any intervention following the 1-week washing out period. Ethical approval has been granted by Ethics Committee of University of Thessaly-Protocol number 2007. All procedures will be conducted in accordance with the declaration of Helsinki, in an appropriately equipped and safe laboratory, by qualified researchers with relevant experience. Research data are confidential and available to participants, who will be allowed to stop their participation at any time without previous notice.