Keywords:
tumor
GASTRIC CANCER, TUMOR, COMPLICATION
Randomized controlled trials (RCTs) of surgical interventions represent the highest level of clinical evidence and often can lead to the widespread adoption of new surgical techniques. However, surgical RCTs are often undertaken in highly controlled clinical environments, in selected patients, and with procedures performed by a selected experienced group of surgeons, often in high-volume centers. Therefore, the generalizability of findings from surgical RCTs to the comparatively uncontrolled environment of national practice is questionable.The Laparoscopic versus Open Gastrectomy for Gastric Cancer trial published in 2021, recruited and randomized patients from 2015 to 2018 between laparoscopic and open gastrectomy.For the patient, gastrectomy may be considered a technically less demanding operation with a lower complication rate when compared with esophagectomy.The aim of this present study was to examine the influence of the LOGICA trial upon the practice and clinical outcomes from laparoscopic gastrectomy nationally within the Netherlands. To achieve this aim, specific objectives of this study were to (1) evaluate patient and tumor factors driving allocation to laparoscopic gastrectomy at a national level; (2) compare clinical outcomes from laparoscopic with open gastrectomy in both the RCT (LOGICA)