Pathophysiological mechanisms
asthma, airway inflammation, asthma [
DISEASE, OXIDATIVE STRESS, ASTHMA
Although the assessment of VOCs is attractive by the non-invasive nature, there is limited understanding of their origin in asthma. VOCs can be formed during various pathophysiological processes, such as airway inflammation and oxidative stress, induced by host and coexisting micro-organisms. Analysing the underlying mechanisms resulting in the formation of predictive exhaled biomarkers such as VOCs, may give insight in the underlying disease pathways leading to the early development of asthma [