Introduction
bleeding, pneumothorax, cancer death, lung tumor, pain, Primary lung cancer
BLEEDING, PNEUMOTHORAX, LUNG TUMOR, AIR EMBOLISM, MALIGNANT TUMORS
Primary lung cancer is one of the most common malignant tumors worldwide and one of the most common causes of cancer death [The traditional choice of opioids in combination with Propofol or Benzodiazepines for invasive procedures in interventional radiology suites is too great a sedative effect for patients to cooperate with the operation, such as breath-holding or lowering the respiratory rate during the puncture process, which increases the risk of bleeding, pneumothorax and air embolism [A single low dose of Esketamine combined with Dexmedetomidine can maintain a mild level of sedation while meeting pain relief needs, which would be well suited for invasive procedures in interventional radiology suites. However, to our knowledge, there has been limited evaluation of Esketamine combined with Dexmedetomidine for lung tumor PRFA sedation.This study aimed to observe and evaluate the effectiveness and safety of Esketamine or Sufentanil combined with Dexmedetomidine for sedation and analgesia in lung tumor PRFA and to compare the advantages and disadvantages of these two drug regimens.