Statistical analysis
tumours, HRD alterations
TUMOURS
Descriptive statistics, including medians and interquartile ranges for continuous variables, as well as percentages and frequencies for categorical variables. The overall response rate with the 95% confidence interval (CI) was calculated by the Clopper-Pearson method. The therapy would be worthy of further investigation if there were ≥1 response in tumours with HRD alterations and ≥4 responses in tumours without evidence of HRD alterations, where the log-rank test was used. The PFS and OS rates with the 95% CIs were estimated using the Kaplan–Meier method. The medians of PFS and OS with the 95% CIs were estimated by the Brookmeyer–Crowley method. Moreover, the median follow-up time was estimated by the reverse Kaplan–Meier method [