Interventions
The whole protocol was conducted inside an environmental chamber (terraXcube, Eurac Research, Bolzano, Italy) and was replicated in both NX (250 m altitude, barometric pressure 744 ± 3 mmHg) and HH (ambient pressure 526 ± 0 mmHg), corresponding to an altitude of 3000 m according to the International Civil Aviation Organisation (ICAO) Standard Atmosphere, and 3170 m according to the Model Atmosphere.