Background
cancers, critically ill, ARDS, septic shock
CANCERS, CRITICALLY ILL, HEMODYNAMIC INSTABILITY, SEPTIC SHOCK, ARDS, ACUTE RESPIRATORY DISTRESS SYNDROME
Among critically ill patients in intensive care units (ICU), early and aggressive fluid resuscitation is indicated to tackle hemodynamic instability [Higher mortality was reported in critically ill patients with a positive fluid balance in various clinical settings, such as septic shock, acute respiratory distress syndrome (ARDS), cancers, and post-operative settings [POINCARE-2 stepped-wedge randomized controlled trial aimed to assess the effectiveness of a conservative strategy on 60-day all-cause mortality in a broad population of critically ill patients [The present as-treated analysis aimed to assess the effectiveness of actual exposure to POINCARE-2 strategy on 60-day mortality in critically ill patients.