Introduction
tumor, cutaneous verrucous carcinoma, squamous cell carcinoma, AJCC, Cancer
SQUAMOUS CELL CARCINOMA, TUMOR, OF SKIN CANCER, CANCER
Ackerman discovered the uncommon and unique form of low-grade squamous cell carcinoma known as cutaneous verrucous carcinoma (CVC) in 1948 (The incidence of CVC appears to be increasing rapidly, and it is now the second most common kind of skin cancer (The American Joint Commission on Cancer (AJCC) Staging Manual includes CVC, and is a significant tool for advising patients, selecting their best treatment, and categorizing them for clinical studies. However, there are a few important limitations in the AJCC staging system for CVC regarding factors that might not be assessed similarly across centers, such as differentiation grading. Another disadvantage is that no independent evaluation of histologic investigations has been performed, and hence risk factors are assumed to be missing if they are not reported. Some pathologic characteristics, such as the tumor depth in millimeters, are not recorded consistently and may impact some instances of AJCC staging. Furthermore, certain AJCC stages of CVC fall short of exact prognostic classification when outcome metrics differ (Nomograms have emerged as a valuable predictive tool in the field of oncology in recent years (The aim of this study was to establish a comprehensive nomogram for CVC patients using the Surveillance, Epidemiology, and End Results (SEER) database, which incorporates essential clinical and pathological features, demographic variables, treatment modalities, and other relevant characteristics. Consequently, the novel nomogram provides clinicians with more accurate and personalized patient survival predictions, superior to AJCC staging system in clinical efficacy. This is may have the potential to enhance population health by promoting improved quality of life and extending lifespan among patients.