Randomization and Interventions
stroke
STROKE
Prehospital paramedics from 86 ambulance bases (128 ambulances) and 2 helicopter bases (2 helicopters) were trained in recognizing stroke and using the PASS stroke severity score.Paramedics consulted all patients with suspected LVO with the stroke neurologist at the CSC by telephone conference. Patients considered trial candidates were screened and randomized using the electronic data capture system, which was accessed via a website by the stroke neurologist. Randomization was performed in blocks of 4 and was stratified by age (<65/≥65 years), geographic region, and PASS score (2 versus 3). Patients were randomly assigned in a 1:1 ratio to either direct CSC admission or admission to the nearest PSC.During the trial period, one of the PSCs was functionally a CSC during daytime. Patients from this center were included only in off-hours (4 