Sample size
We calculated the sample size to detect group differences in three circulating and fecal BA outcomes (total BAs, taurine-conjugated BAs, and DCA) using results reported by Biemann et al. [Normal continuous variables will be presented as mean ± standard deviation. Continuous variables which cannot be transformed to achieve normality will be presented as median (interquartile range). Discrete variables will be presented as percentages.Statistical analysis will be conducted using SAS v9.4 (Cary, NC). Independent and dependent 