Author contributions
RECRUITMENT
S.R., J.G.G., M.G.F., M.R.-C., C.R., E.T., M.A.M.-G., J.S.S., F.B.H. designed the research; D.C., R.E., M.F., L.S.M., M.A.M.-G., J.S.S. coordinated the subject recruitment at the outpatient clinics and clinical data collection in Prevención con Dieta Mediterránea (PREDIMED); C.B.C. conducted the metabolomics data analysis; S.R. and J.G.G. conducted the statistical analysis and drafted the manuscript; S.R., J.G.G, and J.S.S., are the guarantors, and, as such, take responsibility for the integrity of the data and the accuracy of the data analysis; S.R., J.G.G., M.A.M.-G., J.S.S., F.B.H. had access to all the data in the study; S.R., J.G.G., N.B., M.F., J.-P.D.-C., E.T., C.W., M.A.M.-G., J.S.S., F.B.H. interpreted the data; and all authors made critical revisions to the manuscript for key intellectual content and read and approved the final manuscript.