4. Discussion
inflammation, CAD, atherosclerosis
INFLAMMATION, ATHEROSCLEROSIS, CAD, BLOOD
Most of previous air purifiers intervention studies of the elderly did not consider the role of medication, leading to bias in results. In this study, the use of 6 conventional SCAD drugs (statins, β-blockers, Ca-channel blockers, ACEI/ARB, clopidogrel and aspirin) was combined and included into the linear mixed effect model in the form of one “effective drug” variable to analyze the influence of PMInflammation is recognized as a key step in the development of CAD. Clinical studies have indicated that inflammation indicator CRP is a risk biomarker of atherosclerosis, which can mediate atherosclerosis at different stages (Blood lipid is one of the risk factors to be controlled in patients with CAD. The meta-analysis (In the environmental health studies of SCAD patients, medications have a greater impact on cardiovascular indicators than environmental factors, so it's important to control their interference with the results. Stratified analyses by single kind of drug usage are usually used for this purpose (The intervention study considered the influence of daily drug use on cardiovascular indicators of the patients with SCAD, and revealed the real protective effect of air purifiers on the patients with SCAD after reducing PM