Maximum DAIDS QTc* Grade of Visit or change from baseline.
*QTc calculated using the Frederica equation.Note: A change from baseline can result in a graded QTc while the QTc result at the visit is still in the normal range. There was no significant difference between groups using the Kruskall Wallis test.Functional status assessed as ability to work 6 weeks prior to study entry, at time of enrolment, at week 10 and at week 24 did not differ across the cohorts. Likewise, the functional status did not differ in any cohort at any visit. Of those who were alive and for whom the data were available 60% (18/30), 74% (17/33), and 68% (22/33) were back at work or involved in full time activity at week 24 in the 1600mg, 2000mg FCZ, and AMB cohorts. (p = 0ˑ7).