Authors’ contributions
HT
HT, EA, WT, RH, SG, and DM conceptualized and designed the study. HT, EA, WT and RT conducted the experiments. HT, EA, WT, RH, SG, and DM participated in the formal analysis. EA wrote the original draft of the manuscript. HT, EA, WT, RH, SG, and DM reviewed and edited the manuscript. All authors approved the final version of the manuscript. EA supervised the project.