Conclusion
pain
Based on all the foregoing, this study provides evidence that neuron system activation through VR therapy can improve voluntary movement-related capacities (i.e., aerobic capacity, functional lower-limb strength, and reaction time) and pain, while VR therapy has no effect on capacities and characteristics associated with involuntary movement (i.e., static balance and muscle tone and stiffness) in frail and pre-frail people.