Deterministic one-way sensitivity analysis results Tornado plot.
The Tornado plot generated in one-way sensitivity analysis shows the impact on the ICER of changing individual model input parameters their lower and upper bound 95% confidence intervals (shown in parentheses next to each parameter on the plot). Given the negligible impact most parameters had on the ICER the plot is limited to the 20 most impactful model parameters for brevity. ESG endoscopic sleeve gastroplasty, HR hazard ratio, QALY quality-adjusted life year.Results from scenario analyses (Table The threshold analysis on costs associated with the ESG device/procedure showed that these costs would need to be more than five-times higher than in our base-case analysis (>£25,926) for the ICER to exceed the £20,000/QALY willingness-to-pay threshold.