Observation indicators
agranulocytosis, erosion, pain
DISEASE, EROSION, DISEASES, GRANULOCYTOSIS
The main observation indicators used in this study were as follows: (1) the severity of OM and its timing relative to the first day of chemotherapy; (2) the severity of the pain caused by OM and the duration from the onset of pain to its relief; (3) the time from the inception of OM to its healing; (4) the influence of OM on eating, where patients with reduced food consumption, liquid food intake, or an inability to eat due to OM erosion or pain were considered to have an impact on eating and the rest were not; and (5) T-cell subsets of patients detected at the start of agranulocytosis or OM. As with the other indicators examined before treatment, T-cell subsets were re-examined after oral gargle treatment, and the differences between the two groups were compared.According to the World Health Organization (WHO) [Physicians with experience in the treatment of oral diseases evaluated the severity of OM and degree of pain. Unaware of the disease groupings, the same physician assessed the entire observational study process.