Background
depressive, Breast cancer, anxiety
BREAST CANCER, CANCERS
Breast cancer (BC) is one of the malignant cancers with the highest incidence in women worldwide [S-ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, a novel antidepressant drug, can quickly eliminate patient’s depressive state, alleviate anxiety symptoms, and benefit for both physical and mental health of patient [Nevertheless, research on S-ketamine mainly focuses on antidepressant therapy, and few studies have attached importance to patients’ perioperative rehabilitation and cognitive function so far, which is vitally important to patient prognosis. Accordingly, this trial aimed to explore the effects of general anesthesia with S-ketamine on quality of recovery and cognitive function in patient with BC. We hypothesized that general anesthesia with S-ketamine could accelerate the perioperative quality of recovery and improve the cognitive function rehabilitation in patients following an MRM.