Patient and tumor characteristics
tumor
SQUAMOUS CELL CARCINOMA, TUMOR, LYMPH NODE METASTASES, LYMPH NODE METASTASIS
Between January 2014 and July 2019, 31 patients were enrolled in this phase II study at 11 centers in Japan. The number of patients statistically required for this study was 36; however, 31 patients were enrolled as the supply of MMC was suspended from October 2019 onward. The median patient age was 61 years (range, 46–76 years). The clinical tumor stage was cT1 in five patients, cT2 in 16, cT3 in 6 and cT4 in 4. In total, 17 patients presented with clinical evidence of lymph node metastasis (cN+), eight exhibited pararectal lymph node metastasis, three had internal iliac lymph node metastasis, four showed obturator lymph node metastases, and 11 had inguinal lymph node metastasis. Each patient had SCC. Patient and tumor characteristics are summarized in Patient and tumor characteristicsAbbreviations: PS, performance status; SCC, squamous cell carcinoma antigen