Discussion
infection, dysbiosis
PRETERM BIRTH, VAGINA, CERVICAL INCOMPETENCE, INFECTION
The vagina has a multilevel defense system composed of vaginal anatomy, microbiota, the body’s endocrine system, and local immune regulation. The vaginal microbiota is a critical component of the vaginal defense system. The maintenance of a normal pregnancy is closely associated with the balance of the vaginal microbiota. The vaginal microbiota of women with full-term delivery predominantly gravitates towards the The association between cervical incompetence and the vaginal microbiome has increasingly attracted the attention of researchers. Therefore, it is necessary to understand the characteristics of the vaginal microbiome in pregnant women treated with cerclage. A short cervix is associated with decreased abundance of vaginal The present study did not find differences in the relative abundance of vaginal Cerclage is essential for maintaining pregnancy because it maintains cervical length and mucus plugs. It also provides a certain degree of mechanical bearing support for weakened cervical structures. The clinical effects of cervical cerclage are associated with the preoperative vaginal microbiome status. Some researchers have reported that excessive vaginal The present study suggests that high preoperative vaginal microbiota diversity and high abundance of It is well known that infection-related preterm birth is the leading cause of infant mortality and morbidity. Does this act as an invasive procedure that increases the risk of infection or vaginal microbiota dysbiosis? Some researchers believe that thick braided sutures induce dysbiosis of the vaginal microbiota (The present study revealed that the extent of influence of braided sutures on the vaginal microbiome was related to whether it was an emergency cerclage (The aetiology of CIC remains elusive, and effective prevention methods need to be improved. Accurate evaluation of the effects of cerclage and screening of eligible cases for surgery are important clinical problems that should be urgently eliminated. To date, relevant studies have mainly concentrated on analysing clinical data collected from electronic medical records. In-depth analysis of the vaginal microbiome is required to clinically optimise interventional strategies.This study has several limitations. For one, it required larger sample quantities and deviations. CIC’s clinical phenotypes and outcomes of CIC are heterogeneous (