Discussion
This study showed that, in patients with HFrEF, when comparing stimulation with taVNS vs.
We have known since 1998, with the study by Nolan et al.According to the HOPE4 HFFrangos et al. in 2015Zannad and his group, in the NECTAR HF study,Improving the quality of life led to better adherence to treatment, lifestyle, perceptible patient satisfaction, greater engagement when noticing tangible results, and a new focus on their position regarding HF and their expectations.Gold et al., in the INOVATE HF trial,NYHA functional class and quality of life improved after VNS in several studies.In the ANTHEM HF study,In 2015 and again in 2020, in the TREAT AF study, Stavrakis et al.Kaniusas and coworkersIn a recent publication, Sant’Anna et al.