Study approval.
Written informed consent from a parent or legal guardian and assent from the participant, if required, was obtained prior to conducting any study-specific assessments. This study was approved by the IRB affiliated with each individual clinical site: Children’s Hospital Oakland, Oakland, California, USA; Mackay Memorial Hospital-Taipei Branch, Taipei City, Taiwan; Great Ormond Street Hospital for Children NHS Foundation Trust – Great Ormond Street Hospital, London, United Kingdom; Universitätsklinikum Hamburg-Eppendorf (UKE), Hamburg, Germany; Fundación Cardio Infantil – Instituto de Cardiología, Bogotá, Colombia; Complexo Hospitalario Universitario de Santiago (CHUS) – Hospital Clínico Universitario, Santiago de Compostela, Spain; and Gazi Üniversitesi Tıp Fakültesi, Cocuk Sagligi ve Hastaliklari AD, Cocuk Beslenme ve Metabolizma ve Çocuk Genetik Hastaliklari BD, Gazi, Ankara, Turkey.