Synopsis/World Health Organization Trial Registration Data Set {2b}

• The study is funded by an Alexander von Humboldt University Professor Prize awarded to Dr. Till Bärnighausen.• Dr. Alexander Supady is supported by a Berta-Ottenstein-Grant from the Faculty of Medicine, University of Freiburg.Heidelberg University HospitalIm Neuenheimer Feld 67269120 HeidelbergDr. Alexander Supady, MPHUniversity of FreiburgMedical CenterInterdisciplinary Medical Intensive Care Hugstetter Str. 5579106 FreiburgGermanyTel.: +49 761 270-73790Fax: +49 761 270-73792E-Mail: alexander.supady@uniklinik-freiburg.deDr. Alexander Supady, MPHUniversity of FreiburgMedical CenterInterdisciplinary Medical Intensive Care Hugstetter Str. 5579106 FreiburgGermanyTel.: +49 761 270-73790Fax: +49 761 270-73792E-Mail: alexander.supady@uniklinik-freiburg.de