Intervention
pain
BRUCE, BLOOD
The intervention group performed a combination of RT and AT, meanwhile the control group only performed aerobic training. The supervised RT consisted of biceps and quadriceps training. Blood pressure, anthropometric data, baseline electrocardiography (ECG), pain and Borg scales were measured before an exercise program was carried out. The additional RT was composed of 12 sessions performed within 6 weeks (2–3 times per week). Each session is divided into three incremental phases as follows: 1) Phase I (4 sessions): 1 lb./extremity; 2 types of exercise, each 10 repetitions, 2 s concentric/2 s eccentric; 2) Phase II (4 sessions): 2 lb./extremity; 2 types of exercise, each 10 repetitions, 2 s concentric/2 s eccentric; 3) Phase III (4 sessions): 3 lb./extremity; 2 types of exercise, each 10 repetitions, 2 s concentric/2 s eccentric. Exercise dosage was increased by weight increment to ensure progressive overload as individuals progressed, hence facilitating improvements in muscular strength and endurance [Aerobic training protocol was individualized based on six-minute walk test (6MWT), following the protocol developed by Cardiac Prevention and Rehabilitation Division in NCCHK that adopted guideline from American College of Sport Medicine [At the end of study, an exercise stress test was performed with Bruce protocol (GE Healthcare, USA) without a gas analyzer. Peak metabolic equivalent, [