Trial design
enema
This was an assessor blinded, open labeled, single center crossover trial performed at the University Hospital of North-Norway Harstad, Norway. We used contrast fluid (CF) (Barium sulfate suspension 105% w/v, Liquid Polibar Plus, E-Z-EM Canada Inc) as a surrogate liquid for FMT produced in accordance with current European recommendations [The viscosity of the CF was compared to the viscosity of an FMT-treatment (appendix 
Timeline and characteristics of each visit, created with BioRender.comOn the first visit, the examiner finished a complete examination of the colon before delivering CF in cecum, followed by an abdominal X-ray (Fig. 
Contrast fluid delivered by colonoscopy, created with BioRender.comAfter a washout period of four to eight weeks, participants underwent a bowel lavage with Sodiumpicosulphate/Magnesiumcitrate (Picoprep/Ferring) before returning to the hospital to receive CF, now delivered as an enema (Fig. 
Contrast fluid delivery by enema before and after the positioning procedure, created with BioRender.comImmediately after enema delivery, participants were (with minimal movement) lifted to another table for an X-ray (enema ÷). Next, lying on the bench, participants were instructed to follow the positioning procedure described in Fig. 