2.2. Inclusion and Exclusion Criteria
mental illness, allergy, cognitive impairment, liver and kidney insufficiency
ALLERGY, CARDIOPULMONARY DISEASE, DIGESTIVE TRACT DISEASE
From January 2019 to June 2021, 201 patients who underwent TKA were subjected to a strict eligibility review. The inclusion criteria were as follows: patients who received elective, initial, and single TKA. The exclusion criteria were as follows: (1) patients with an American Society of Anesthesiologists (ASA) classification of grade 4 or higher, (2) patients with a history of liver and kidney insufficiency, severe cardiopulmonary disease, severe digestive tract disease, and mental illness, (3) patients with an allergy to celecoxib or pregabalin or to anesthetic drugs, (4) patients who had taken celecoxib or pregabalin within 2 weeks before surgery, and (5) patients with cognitive impairment. A total of 160 patients were finally included in the study.