Objectives and hypotheses
OUD, pain
SECONDARY
The primary objective (Aim 1) is to determine the efficacy of the STOP collaborative care intervention, in comparison to enhanced usual care (EUC), for reducing risky opioid use in adult primary care patients. Risky opioid use is defined as nonmedical use of prescribed opioids (e.g. more than prescribed or non-prescribed opioids) or any use of illicit opioids. We hypothesize that patient participants with PCPs assigned to the STOP intervention, relative to patient participants with PCPs assigned to EUC, will have fewer days of risky opioid use, measured at 6 months post-baseline (primary outcome), and at 3-, 9-, and 12-months post-baseline (secondary outcomes).Secondary objectives capture patient participant (Aim 2) and provider participant-level outcomes (Aim 3). We hypothesize that patient participants with PCPs assigned to the STOP intervention, in comparison to those with providers assigned to EUC, will have improved measures of other substance use, quality of life, mental health symptoms and no worsening of pain severity. For PCPs in the study (provider participants), we hypothesize that providers assigned to the STOP intervention, in comparison to those assigned to EUC, will adopt improved treatment practices that include safe prescribing of controlled substance and increased monitoring for patients with subthreshold OUD. Specific secondary outcomes are detailed below and in the Additional file 