Trial design and participants
SECONDARY
The ProCCM trial was conducted in the health district of Bankass in central Mali, located about 600 km northeast of the national capital Bamako. The 2016 population of the study area was approximately 100 000, which composed of seven contiguous health catchment areas. Each area was served by one primary health centre (PHC) and a secondary referral hospital that was located within the district but outside the study area. Households in the study area generally included extended family ties and were geographically colocated within one family compound. Women were eligible to participate if they were between 15 and 49 years and permanent residents with no plans to relocate out of the study area during the trial. Once enrolled women remained in the trial even if they aged beyond 49 years.Villages and hamlets within 1 km from one another were grouped into clusters. A total of 160 individual villages and hamlets were grouped into 137 unique clusters that covered the seven catchment areas entirely.