Strengths, limitations, and future studies
This is the first study to evaluate the cost-effectiveness of three PE-based interventions for patients with CA-PTSD. The pragmatic and naturalistic design of the study enhances the generalizability of the results to clinical practice. Moreover, missing values on outcome variables were estimated using multiple imputation to retain the full sample size and use as much information from the data as possible.Next to these strengths, limitations need to be acknowledged. First, patients’ healthcare usage and productivity losses were based on self-reports. Self-report registrations may be more sensitive to errors than data from healthcare services and employers. Yet, it was previously shown that agreement between patient’s self-reported healthcare usage and data provided by health services was high (Bouwmans et al., 