Urine sampling
Urine samples were collected by the participant directly into 30 mL aseptic containers (Alpha Laboratories Ltd). Samples provided were the first urination of the day after the morning void. Upon receipt from the participant, samples were refrigerated (within 30 min) then (within ∼1 h of refrigeration), were poured into 3 × labeled, small screw cap tubes (Greiner Bio One Ltd) before being stored at –20°C prior to analysis.