Study design and patients
RIFLE, AKI, anuria, reduced urinary output, oliguria
ANURIA, OLIGURIA
This The failure (F) stage of the RIFLE classification, which was used in the IDEAL-ICU study, corresponds to stage 3 of the KDIGO classification, and is the preferred term used hereafter [For the present analysis, we defined three groups, according to the criteria that had been used to define AKI and qualify patients for inclusion in IDEAL-ICU: patients who were enrolled solely on the basis of creatinine elevation (group 1), patients who were enrolled solely on the basis of reduced urinary output (oliguria or anuria – group 2) and patients who presented both criteria (group 3).The original trial was approved by the competent French legal authorities, and the ethics committee 