2.4. Outcome assessment
MODS, tumor necrosis, infection
MODS, SECONDARY, TUMOR NECROSIS, INFECTION
All clinical and imaging data and treatment were subjected to assessment by a masked independent diagnostic and assessment committee. This committee included 2 researchers who were trained before the start of the present research and did not engage in the clinical care of patients. The primary endpoint of this study was 30-day mortality. The secondary endpoints included the incidence of MODS; inflammatory cytokine levels (pretherapy and posttreatment), such as serum tumor necrosis factor-α and interleukin-6; coagulation function, such as the plasma prothrombin time, activated partial thromboplastin time and fibrinogen (FIB) levels, was measured using an automatic coagulation analyzer; serum infection index levels, such as white blood cell count, C-reactive protein, and procalcitonin; liver function index levels, such as alanine aminotransferase and aspartate aminotransferase; and renal function index levels, such as creatinine and urea nitrogen.