Translating the Schedule From Mice to Humans Using Mathematical Modeling
toxicity, tumor
TUMOR
We used our mathematical model, described in Leder We performed toxicity modeling using the biologically effective dose formalism based on the linear-quadratic model of radiation dose response.where We constrained We performed sensitivity analyses by using the model to simulate the impact of different interfraction intervals and starting the schedule on different days of the week on the predicted tumor response dynamics. Code for our analyses is available at 