3.4. Effects of CV on Skin Melanin Index and Wrinkles
To assess the whitening effect of CV, the melanin index measurement results are shown in Wrinkles were measured using PRIMOSCR (GFM, Teltow, Germany) at the right-angle intersection of the nose and the tip of the eye. Wrinkle parameters included Ra (average roughness), Rmax (maximum peak to valley distance over the assessment length), and Rz (average maximum profile height). After eight weeks of sample intake, the Ra value in the combination group decreased from 21.093 ± 2.620 μm to 19.869 ± 2.851 μm, that of the caviar group decreased from 23.347 ± 5.647 μm to 22.007 ± 4.823 μm, and that of the placebo group decreased from 18.862 ± 3.360 μm to 19.005 ± 2.934 μm. The change in Ra value was significantly improved in both treatment groups (The Rmax value decreased from 244.442 ± 46.975 μm to 234.957 ± 36.421 μm in the combination group and from 249.927 ± 61.225 μm to 235.144 ± 61.048 μm in the caviar group, while it increased from 224.223 ± 36.487 μm to 226.752 ± 27.608 μm in the placebo group. There was a significant improvement only in the caviar group compared to the placebo group (The Rz value of the combination group decreased from 114.493 ± 14.097 μm to 107.556 ± 15.006 μm, that of the caviar group decreased from 124.783 ± 29.388 μm to 116.770 ± 24.634 μm, and that of the placebo group increased from 103.663 ± 17.749 μm to 104.239 ± 14.970 μm. The change in Rz value was significantly improved in both treatment groups compared to the placebo group (