2.4.1. Oral Glucose Tolerance Test
BLOOD, INSULIN RESISTANCE
A 75 gm oral glucose tolerance test was performed at screening and at 16 weeks after an overnight 12 h fast. Blood was sampled from an indwelling venous cannula for glucose and insulin concentrations at baseline and at 30 min intervals up to 120 min. Insulin sensitivity was assessed using the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) and the Matsuda index [