Statistical analysis
anxiety
Statistical analysis was performed using SPSS version 20.0. Categorical variables were summarized using numbers and percentages. Quantitative variables were expressed as mean ± standard deviations (SD) or as median (interquartile ranges, IQR) after testing for normality. The Student’s t-test for independent samples, Mann Whitney, Chi-square and Fisher’s exact t-tests were used to compare the baseline characteristics of the two study groups. For each group, the Wilcoxon test was used to compare the HAD-A score on Day1 and Day 7 and the McNemar test to compare the prevalence of anxiety on Day 1 and Day 7. The DELTA difference between the scores (HAD-A 