Cosmesis
telangiectasia
For cosmesis following WLE and telangiectasia following mastectomy or WLE, data were compared to baseline from the first follow-up visit to 5 years post-surgery. Data were classified as improved, stable or worsened, and a Fisher's exact test used to assess the differences. Odds ratios of moderate/poor versus excellent/good assessment comparing synchronous to sequential CRT treatments were analysed using each patient's last available assessment compared to baseline. For acute skin reactions, odds ratios of moderate/severe versus none/mild comparing synchronous to sequential CRT treatments were analysed at the two time points. For the independent review, odds ratios of marked/mild versus minimal comparing synchronous to sequential CRT treatments were analysed using each patient's last available assessment compared to baseline. For each cosmesis-related QoL question, data from the patient's last available assessment were classified as improved, stable or worsened and a Fisher's exact test used to assess the differences.