Sample Size Calculation and Randomization
Considering the FSFI score as the primary outcome, a sample size of 33 women was calculated for each group, accepting an α risk of 0.05 and a β risk of less than 0.1 in a bilateral contrast. The common SD was considered to be 5 points, and the minimum expected effect size was 4 points.Participants were equally assigned by 1:1 block randomization to either CLT or SLT using Stata software version 15.1 (StataCorp). The block sizes were 8. Allocation concealment was performed using a protected personal code folder on the hospital intranet. Access to the randomization folder was limited to an authorized collaborator physician who had no other involvement in the study.