Statistical analysis
ALI, Demographic and disease, depressive, depressive symptoms, depression
REGRESSIONS
Demographic and disease characteristics of the sample were summarized and scores on depression and biomarker ratio levels and cutoffs provided. In order to avoid overfitting the survival models, covariates for analysis were selected based on a cutoff of p < 0.20 from univariate models Next, multiple linear regressions tested the association of patient depressive symptoms (PHQ-9) with elevated NLR, elevated PLR, and lower ALI, adjusting for relevant covariates. NLR, PLR, and ALI were log-transformed due to right-skewed distributions. Descriptive analyses show the percentage of patients with no/low versus high depressive symptoms stratified by low versus high SIR levels. A p-value of 0.05 was used as a cutoff for significance. Analyses were performed using R 4.1.1. [