Pharmacokinetic data analysis
PK data analyses were performed using the data from all enrolled subjects who had at least one plasma concentration post-dosing. PK parameters for ibrexafungerp were calculated with standard non-compartmental analysis using Phoenix WinNonlin (Certara USA, Inc., version 8.1) and were summarized by study part and cohort using SAS (version 9.4, SAS Institute Inc., NC, USA). Plasma concentrations of HS-10366 were summarized and plotted using Phoenix WinNonlin (Certara USA, Inc., version 8.1).