Introduction
respiratory disease
CORONAVIRUS, RESPIRATORY DISEASE, CORONAVIRUS DISEASE 2019, SEVERE ACUTE RESPIRATORY SYNDROME
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a highly contagious respiratory disease that has radically impacted the world since its emergence in December 2019 (The development of COVID-19 vaccine has been a top priority since the beginning of the pandemic, leading to an expedited timeline for vaccine development. Scientists and biopharmaceutical companies around the world have been working relentlessly to develop safe and effective vaccines to prevent COVID-19 (As required by NMPA, lot-to-lot consistency studies were recommended to be carried out to provide stability data of commercial-scale CoronaVac. A previous phase IV clinical trial in health adults aged 26-45 years showed lot-to-lot consistency of three lots of CoronaVac on a commercial scale (