Study design
This study used a double‐blind, placebo‐controlled crossover design to examine the acute effects of MitoQ supplementation on metabolic responses during exercise (Figure Timeline of experimental trials. Participants completed two trial days in a randomized double‐blind, placebo‐controlled crossover design. Timeline in minutes. RER, respiratory exchange ratio.During the first visit, written informed consent was collected and a health history questionnaire was completed to confirm eligibility. The first visit also included the collection of baseline resting data including anthropometrics, body mass index (BMI and DXA), resting ECG, glucose and lipid panel, and assessment of vascular hemodynamics. Upon arriving at the CEP lab for visits two and three, height and weight were measured, followed by consumption of either 80 mg of MitoQ (MitoQ Limited, Auckland, NZ) or placebo which consisted of empty gelatin capsules similar to our previous research (Harber et al., 