Hemodynamic Measurements
myocardial ischemia
MYOCARDIAL ISCHEMIA
Coronary microvascular function assessments were performed with a wire-based thermodilution method using Pressure Wire X (Abbott Vascular) as per instructions for use; the same hyperemic agent was used for the 2 sets of measurements in each patient (sham and balloon). The mean transit time (Tmn), coronary flow reserve (CFR), and IMR were measured. The absence of drift was confirmed at the end of the measurements. Patients were blinded to the randomization sequence, and hemodynamic data were encoded in the CoroFlow software (Coroventis) and collected by blinded assessors. Coronary flow capacity was measured to identify 4 different regions of myocardial ischemia (eMethods in 