Study Population
primary invasive breast cancer
Eligible patients were women with histologically confirmed, operable primary invasive breast cancer with known hormone receptor status, Chemotherapy was administered before radiotherapy if radiotherapy was indicated. Radiotherapy was completed by patients who received breast conservation or with 4 or more involved axillary lymph nodes or those with 1 to 3 involved axillary lymph nodes along with other high-risk factors. On completion of chemotherapy and/or radiotherapy, endocrine therapy (the regimen was decided by the physicians) was administered to patients for 5 years.