Discussion
SrODecreased cardiac output
VASODILATION, INTERNAL CAROTID ARTERY STENOSIS
Cerebral oxygen detector was used to detect the cerebral oxygen saturation of patients, which is a non-invasive real-time detection to analyze the oxygen supply level of patients’ brain tissue [In our study, remimazolam was noninferior compared with propofol in terms of oxygen saturation. SrODecreased cardiac output during induction of general anesthesia or imbalance of cerebral perfusion pressure/cerebrovascular resistance may be the reason of decreased cerebral perfusion and thus decreased cerebral oxygen supply. The results of this study showed that the levels of Vm, CI and HR decreased during anesthesia induction, reached the minimum value before intubation in both groups. However, it was noted that propofol has a greater influence on patients’ blood pressure, leading to a larger decrease in MAP in group P after induction. This result suggests that, compared with propofol, remimazolam may have more advantages in hemodynamics of patients as anesthesia inducing drug, and this result is basically consistent with previous research results [However, the vascular resistance index RI remained basically stable at each time point, with no statistically significant change amplitude or difference between the two groups. We consider that the patients in this study are all elderly patients with poor regulation ability of their own blood vessels, and severe internal carotid artery stenosis induces blood–brain barrier injury and impairs the autoregulation to interrupt vasodilation or vasoconstriction [Data from the research showed that after the induction of general anesthesia, the BIS value of P group was lower than that of R group due to the effect of remimazolam was slowly [To our knowledge, this is the first study applying remimazolam for the induction of anesthesia on carotid endarterectomy. We found that remimazolam-sufentanil anesthesia induction was comparable with propofol-sufentanil anesthesia induction in an aspect of preserving the SrO