Intervention
T2DM
The study intervention has been described in detail [Glargine, administered at bedtime, with doses titrated to target fasting glucose ≤ 5.3 mmol/l;Glargine at bedtime with thrice-daily pre-meal lispro, with doses titrated to target fasting glucose ≤ 5.3 mmol/l and 2-h postprandial glucose < 8 mmol/l;Glargine at bedtime with twice-daily exenatide before breakfast and dinner at doses of 5 ug twice daily for the first 4 weeks, followed by 10ug twice daily for the next 4 weeks (glargine titrated to target fasting glucose ≤ 5.3 mmol/l).The assigned intervention was stopped at 8-weeks, after which participants entered a 12-week washout during which they were advised to follow healthy lifestyle practices for managing T2DM [