Secondary endpoints
allergic symptoms, itching
SECONDARY, ALLERGIC RHINITIS
A secondary endpoint measure is the Total Nasal Symptoms Score (TNSS). The TNSS is well-known to describe symptoms in allergic rhinitis. In contrast to other questionnaires the TNSS focuses on nasal symptoms. Participants have to rate five different nasal symptoms (e.g., itching or sneezing) on a scale from “0” (= not at all) to “3” (= symptoms difficult to bear, interfere with activities) with respect to the last 12 h and the last two weeks. Hence, lower scores reflect less symptoms. The TNSS is well-known and has been validated for many languagesIn addition, we asked the participants to complete a daily diary. Patients had to use visual-analogue scales (VAS) to measure the daily burden of allergic symptoms