Results
restless, Anxiety, Postoperative nausea and vomiting, pain, cough, PONV - postoperative nausea and vomiting.†Data, coughing or bucking, 5 = poor extubation, PONV
ADVERSE EVENTS, ADVERSE EVENT
Of 73 women who were initially screened for eligibility, six were excluded. Consolidated Standards of Reporting Trails flow diagram of the study.Demographic data of patients who received an IV lidocaine 1.5 mg/kg bolus or saline placebo**Abbreviations: ASA - American Society of Anesthesiology; H/o - history of; PONV - postoperative nausea and vomiting.†Data are expressed as mean ± standard deviation, median (min-max value) or n (%).Perioperative data of patients who received an IV lidocaine 1.5 mg/kg bolus or saline placebo*APAIS - Amsterdam Preoperative Anxiety and Information Scale (score >11 identifies an anxious patient).†Data are expressed as mean ± standard deviation or median (min-max value).A IV lidocaine bolus on emergence was administered about eight minutes before extubation in both groups and did not delay extubation. All emergence variables, either by subjective (emergence and extubation scores) or objective criteria (bucking and hemodynamics), were significantly improved (Emergence data of patients who received an IV lidocaine 1.5 mg/kg bolus or saline placebo**Abbreviations: SBP - systolic blood pressure; MBP - mean blood pressure; DBP - diastolic pressure, HR - heart rate.†Data are expressed as mean±SD, median (min-max value), or n (%).‡Extubation Quality Score: 1 = no cough or bucking, 2 = very smooth, minimal coughing, 3 = moderate coughing, 4 = large degree of coughing or bucking, 5 = poor extubation, very uncomfortable. Quality of awakening score: 0 = calm patient, no adverse events, cooperative patient; 1 = calm patient, one adverse event, patient trying to cooperate; 2 = restless, one adverse event, uncooperative patient; 3 = restless, at least two adverse events, trying to cooperate; 4 = restless, at least two adverse events, uncooperative patient.Lidocaine also significantly improved recovery after extubation (Recovery data of patients who received an IV lidocaine 1.5 mg/kg bolus or saline placebo**Data are expressed as n (%) or median (minimal-maximal value).IV lidocaine bolus on emergence reduced PONV at all measurements, but a significant difference was observed only in late PONV (3% vs 24%, Postoperative nausea and vomiting (PONV) data of patients who received an IV lidocaine 1.5 mg/kg bolus or saline placebo**Data are expressed as n (%).Postoperative pain of patients who received an IV lidocaine 1.5 mg/kg bolus or saline placebo**Data are expressed as n (%) or median (minimum-maximum value).