Trial design
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BLIND
The study was conducted as monocentric, controlled, randomized, blind cross-over comparative study on 20 volunteers (Table The reduction of bacteria was evaluated on the buccal cheek mucosa and in saliva of the volunteers. The test products were coded using the letters A (Granudacyn®), B (Octenidol® md) and C (Ringer solution).Allocation ratio was 1:1. Every volunteer received every rinsing solution once in consecutive weeks.
Use of test products in the cross over design