1. Introduction
There is limited evidence regarding implementing organisational improvements in the cultural responsiveness of non-Aboriginal services. Using a pragmatic implementation process to promote organisational change around cultural responsiveness, we aimed to (i) identify its impact on the cultural responsiveness of participating services; (ii) identify areas with the most improvement; and (iii) present a program logic to guide cultural responsiveness. A best-evidence guideline for culturally responsive service delivery in non-Aboriginal Alcohol and other Drug (AoD) treatment services was co-designed. Services were grouped geographically and randomised to start dates using a stepped wedge design, then baseline audits were completed (operationalization of the guideline). After receiving feedback, the services attended guideline implementation workshops and selected three key action areas; they then completed follow-up audits. A two-sample Wilcoxon rank-sum (Mann–Whitney) test was used to analyse differences between baseline and follow-up audits on three key action areas and all other action areas. Improvements occurred across guideline themes, with significant increases between median baseline and follow-up audit scores on three key action areas (median increase = 2.0; Interquartile Range (IQR) = 1.0–3.0) and all other action areas (median increase = 7.5; IQR = 5.0–11.0). All services completing the implementation process had increased audit scores, reflecting improved cultural responsiveness. The implementation process appeared to be feasible for improving culturally responsive practice in AoD services and may be applicable elsewhere.There are substantial inequalities in health status and health care access between Aboriginal and Torres Strait Islander people (hereafter referred to as Aboriginal) and non-Aboriginal people in Australia [Cultural responsiveness initiatives have been shown to improve healthcare worker cultural knowledge, awareness and sensitivity [While many non-Aboriginal clinicians are individually committed to practising in a culturally responsive way, improving cultural responsiveness needs to be a whole-of-service activity that involves multiple strategies across all levels of the workforce and organisational policy, management and practices to be effective [The core components, or themes, of the guideline were then operationalised into flexible activities that could be tailored to suit each service [