Genotyping and HBV/HDV reference sequences
Verification of HBV DNA and HDV RNA sequences was carried out using the Nucleotide BLAST application as well as using the Genotyping (HBV) application [Genotyping of HBV/HDV isolates was carried out using phylogenetic analysis of null-binary sequences of Kazakhstani isolates, in comparison with the reference sequences indicated above and the data obtained during Nucleotide BLAST. Nucleotide sequence alignment was performed using the ClustalW algorithm of the Molecular Evolutionary Genetic Analysis (MEGA) version 7, and for the construction of phylogenetic trees and subsequent analysis, the method “neighbor-joining (NJ)” was used [