RWD—Evaluating the association between dR and overall survival
The nationwide Flatiron Health EHR-derived de-identified database is a longitudinal database, comprising de-identified patient-level structured and unstructured data, curated via technology-enabled abstraction and subject to obligations to prevent re-identification and protect patient confidentiality [Treatment regimens received by patients in the database were categorized as follows: chemotherapy+steroid, PI+steroid, IMiD+steroid, PI+IMiD+steroid, PI+chemotherapy+steroid, chemotherapy+IMiD+steroid, IMiD+monoclonal antibody+steroid, PI+monoclonal antibody+steroid.Overall response (≥PR) to first-line treatment was derived for these patients using the dR algorithm. Associations between overall response rate and real-world overall survival were distinguished at both the individual and treatment level (