Discussion
PIH, supraglottic airway, hypotension
A remarkable proportion of patients (> 70%) in this study developed hypotension. This is higher than the general population and supports the finding that the patients routinely administered angiotensin axis blockades are vulnerable to PIH [In cases of intraoperative hypotension, the amount of reduction in the blood pressure is also critical [Another benefit of remimazolam as an induction agent is that the drug has the antagonist. There are some cases where rapid recovery after loss of consciousness is required. One example is difficult airway management. According to the multiple airway management guidelines, emergence and recovery of spontaneous ventilation are warranted in cases of supraglottic airway or endotracheal tube placement fails, but oxygenation is still possible [A trend of higher BIS was observed in participants administered remimazolam than in those who were administered propofol. Previous studies have reported a discrepancy between the BIS and sedative state in patients administered remimazolam [Our study has certain limitations. First, due to the loading dose of remimazolam in group R, the effect-site concentration after the loss of consciousness could be higher in group R. Further study adopting a target-controlled infusion model is required to overcome this limitation. Second, generalizability is limited due to the exclusion of high-risk surgical populations who require preparation for intensive care units. In addition, long-term postoperative outcomes, such as 30-day mortality, have not been studied. Further well-designed studies addressing the long-term postoperative impact of intraoperative hypotension in patients administered ARB or ACEI are warranted.