Statistical methods for primary and secondary outcomes {20a}
Descriptive statistics will be used to present the participants’ characteristics. Baseline demographic data will be compared across groups and the participating EDs to establish the comparability of study samples across intervention arms and clusters. If differences are observed, statistical models will be adjusted, and any difference will be considered. Descriptive statistics will be computed for all outcome measures at different measurement times. Per-protocol and intention-to-treat analysis will be performed. Outcomes will be analyzed at the individual level using mixed models as recommended for stepped-wedge designs [