CONCLUSION
Despite identification of overall between‐trial differences in CBF, acute vigorous‐intensity running did not directly influence the time‐course of CBF suggesting food‐cue related BOLD acquisitions immediately after exercise may not be time sensitive at least in relation to any residual influence of CBF. Acute running transiently suppressed appetite and increased food cue reactivity in brain regions implicated in attention, anticipation and encoding of reward, and episodic memory retrieval independent of CBF. These data provide insights into the immediate effects of exercise on central appetite responses and highlight important methodological considerations for future work exploring the interaction of exercise with brain food‐cue responsiveness.