Exclusion criteria
liver or kidney failure, Active infectious diseases, gastrointestinal tract
HEPATITIS B
The exclusion criteria included:
Patients taking antibiotics during the study,Patients with concurrent hepatitis B and C,Patients not adhering to pill regimen,Pregnancy during the study,Active infectious diseases,Surgical procedures 6 months before or during the study on the gastrointestinal tract,Severe liver or kidney failure.