Introduction
infection, infections, coronavirus disease 2019
CORONAVIRUS DISEASE 2019, SARS-COV-2 INFECTION, INFECTIONS, INFECTION, CORONAVIRUS, SEVERE ACUTE RESPIRATORY SYNDROME
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), known as the etiology behind the coronavirus disease 2019 (COVID-19) worldwide pandemic, has resulted in significant mortality rates worldwide. Solid organ transplant (SOT) recipients, not unexpectantly, are more likely to experience poor outcomes after SARS-CoV-2 infection including higher hospital admission rates and increase mortality (Other than the natural immunological response against infections, vaccination and monoclonal antibody therapy are the other pathways available to augment the immune systems response to this infection. The United States Food and Drug Administration provided emergency use authorization for ticagevimab/cilgavimab as primary prophylaxis in high-risk patients such as immunocompromised recipients including SOT recipients (Although the high efficacy of COVID-19 vaccines is well documented in the general population (We hypothesized that the mix and match method, i.e., using the different type of vaccine as a booster, would provide higher immunogenicity in SOT recipients. However, there are two studies comparing the mix and match method vs. uniform method in SOT recipients: one multicenter prospective, non-randomized, study and one randomized controlled trial (