Introduction
cancer, PDAC, fibrosis, Fibrosis, pancreatic cancer
PANCREATIC DUCTAL ADENOCARCINOMA, PANCREATIC NEOPLASMS, CANCER, FIBROSIS, FIBROSIS, MALIGNANCIES, PANCREATIC CANCER, LIVER METASTASIS
Pancreatic ductal adenocarcinoma (PDAC) accounts for more than 80% of pancreatic neoplasms and is one of the most lethal malignancies all over the world with a 5-year survival rate of around 8% [Radiomics were first proposed by Lambin in 2012, which were based on large amounts of high-throughput features extracted from magnetic resonance imaging (MRI) or computerized tomography (CT) images [Meanwhile, cancer associated fibroblasts (CAFs) are the main composition of stroma in pancreatic cancer and take part in fibrosis process in pancreatic cancer [In this study, we established and validated an MRI radiomics model to predict the risk of liver metastasis for PDAC patients. Fibrosis markers can promote our risk model but need further validation.