4. Discussion
TG
Our study investigated the effects of TRE with and without BE on patients with IFG. The results showed that neither TRE plus BE nor TRE alone had a significant impact on FPG, HbA1c, body weight, DBP, lipid profiles, and fasting insulin levels when compared to usual care. However, when comparing TRE plus BE to usual care, there was a significant reduction in SBP. Additionally, when comparing TRE alone to usual care, a significant decrease in hs-CRP levels was also observed. When considering the “as-treated” analysis, complying with the TRE protocol brought significant improvements in FPG, HbA1c, serum TG, fasting insulin, HOMA-IR, and DBP levels when compared to usual care alone.