Association of resistance training-induced changes in muscle strength with changes in brain neurometabolite ratios
The results of Pearson’s correlation indicated both ∆PT of knee extension and flexion were positively associated with ∆SM1 tNAA/tCr, ∆SM1 Glx/tCr, and ∆dlPFC Glx/tCr. Contrary to what we expected, there was also a positive correlation between ∆PT knee flexion and ∆dlPFC mIns/tCr. The correlation of ∆PT of knee extension with ∆SM1 tNAA/tCr did not survive the FDR correction for multiple testing, while with ∆SM1 Glx/tCr (The linear relationship that survived FDR procedure between changes in strength and neurometabolite ratios were Following the sub-classification of experimental group participants by peak torque gain, the responders showed a positive association between ∆PT knee extension and ∆dlPFC Glx/tCr that survived FDR correction (Table The relationship between changes (∆) in PT knee extension/flexion after resistance training with changes (∆) in brain neurometabolite ratios among responders and non-respondersSpearman’s rank correlation coefficient analysis for ∆ PT of knee movement. **