Neoadjuvant chemotherapy
tumor, neutropenia, diarrhea
ADVERSE EVENTS, ASYMPTOMATIC PULMONARY EMBOLISM, NEUTROPENIA, TUMOR
The median number of nCT cycles was 5 (range: 1–5). Six of 50 (12%) patients failed to complete 5 cycles of nCT. Two patients discontinued because of adverse events (1 case of grade 3 diarrhea with grade 4 neutropenia related to nCT and 1 asymptomatic pulmonary embolism unrelated to the treatment). Two patients showed no evidence of any tumor shrinkage on the first evaluation with MRI, and then received CRT and 2 patients withdrew informed consent. The patients flow diagram is shown in Fig. Patients flow diagram