1. Introduction
opportunistic infection
OPPORTUNISTIC INFECTION, VIRUS, UPPER RESPIRATORY TRACT INFECTIONS
This study was conducted to compare the effects of long-term prebiotic and synbiotic supplementations on the immunosuppression of male football players after daily high-intensity training and a one-time strenuous exercise. A total of 30 male university student-athletes were recruited and randomly assigned to the prebiotic (PG, n = 15) or synbiotic group (SG, n = 15), receiving a prebiotic or synbiotic once per day for six weeks. Physiological assessments were conducted by a maximal oxygen uptake (VO2max) test and an exhaustive constant load exercise (75% VO2max test). Inflammatory cytokine and secretory immunoglobulin A (SIgA) were measured. VO2max, maximal heart rate (HRmax), and lactic acid elimination rate (ER) were used to evaluate aerobic capacity. Upper respiratory tract infection (URTI) complaints were evaluated using a questionnaire. URTI incidence and duration were significantly lower in the SG group than that in the PG group (Exercise-induced immunosuppression is a common phenomenon among elite athletes after intensive exercise, which can easily increase the risk of opportunistic infection and virus reactivation [Probiotics are living microorganisms that can benefit the health of the host when consumed in sufficient amounts [