Statistical CBF analysis
migraine
MIGRAINE, DISEASE, MIGRAINE WITH AURA
The statistical analysis of the MRI data aimed to investigate whether (i) baseline CBF differs between migraineurs and HC, and (ii) active tDCS treatment leads to differences in the CBF compared with sham.To that end, first, we compared the relative CBF at baseline of migraineurs and HC using a t-test corrected for age and sex. Then, we compared, by a repeated-measured ANOVA with the factors group (2: real and sham) and time (3: baseline, F1, and F2), the active and the sham treatment group at baseline, F1 and F2 cross-sectionally and corrected for age, disease duration, aura type (migraine with aura and migraine without aura), and the number of migraine days during the baseline period.For these analyses (i.e. ANOVAs and t-tests), we applied a voxel-wise threshold of 