Chronotherapy and metabolite profiles
leukopenia, inflammatory bowel disease
DISEASE, LEUKOPENIA, SIDE EFFECT, INFLAMMATORY BOWEL DISEASE
No participants had significant disease flares or significant side effect such as leukopenia or increased liver function tests during the 10-week intervention period where they changed the timing of the medication. The mean AM vs PM metabolite levels: 6-TG Impact of chronotherapy on azathioprine/6-mercaptopurine (AZA/6-MP) metabolites. Metabolite levels measured at 2 different time points in each inflammatory bowel disease individual, either in the 