Prescription of no or narrow-spectrum antibiotics
There were 3 missing samples due to POC-PCR assay failure. Thus, no clinical characteristics influenced the missing mechanism. Therefore, we believe the data are missing completely at random. However, for sensitivity reasons, multiple imputation was performed. Results from per protocol and intention-to-treat analysis were similar. POC-PCR was not superior to SCO regarding prescriptions of no or narrow-spectrum antibiotics within 4 h after admission. Intention-to-treat analyses of 294 patients yielded an OR 1.13; (95% CI [0.96, 1.34] 