Study design and population
stroke
MYOCARDIAL INFARCTION, STROKE, TRANSIENT ISCHEMIC ATTACK (TIA), AORTIC STENOSIS
This was a randomized, controlled trial undertaken at East Sussex Healthcare NHS Trust, UK. All patients provided written informed consent. The study was approved by the UK National Research Ethics Service and conducted in compliance with the Declaration of Helsinki.Subjects were included if their age was greater than or equal to 18 years and if they were referred for atrioventricular node ablation for any appropriate indication. Exclusion criteria included a recent stroke or transient ischemic attack (TIA) within 6 months, myocardial infarction within 6 months, medical conditions limiting expected survival to less than 1 year, moderate to severe aortic stenosis, a history of aortic or mitral valve replacement, and pregnancy or breastfeeding women.