Results
deaths
PATHOLOGY
From 22nd January 2019 to 19th March 2021, we enrolled a total of 230 patients. Two patients were later excluded due to final pathology report requiring a different treatment than that of our inclusion criteria and another did not initiate treatment. The analysis therefore included 228 patients, Fig. CONSORT diagram of patients enrolledThe clinical data of the 228 patients are shown Table Clinical dataWe observed no difference in rate of hospital admissions (OR 1.48, 95% CI 0.83–2.65, Endpoints. NA: It was not possible to find upper confidence levels for median overall survival due to too few deaths during the study periodKaplan–Meier curve of overall survival in both study groupsCox proportional hazards model for survivalGlobal QoL for all patients was stable over time (Mean Global QoL 61–63 (SD: 22–26)). At the end of the study period global QoL increased for the intervention arm while the control arm experienced a decrease in QoL, although this difference was not statistically significant, Table Quality of life and questionnaire completion over timeMean global quality of life over the course of the studyMean quality of life over the course of the study. Completion rate of electronic questionnaire for all patients was 69–88% through the course of 0–18 weeks with the highest completion rate (88.6%) at week 0. The completion differed between the two groups, as illustrated by Fig. Questionnaire completion rate over time for both armsThe level of clinician compliance was determined by number of logs into the Ambuflex system coinciding with a completed questionnaire and compared with number of planned visits (as expected according to number of completed cycles of treatment). We found that the intervention group had a total of 495 completed cycles of treatment. The number of clinician logs into Ambuflex for the intervention group was 466, equaling a clinician compliance of 94%. However, against the intention of the study, we also found a clinician log into Ambuflex for the control group of 240. The control group had a total of 467 completed cycles equaling an unintended clinician log into Ambuflex (which did not show any listing of EORTC or PRO-CTCAE data) of 51%.