LTB- and O78 LPS-specific IgA and IgG immune responses
®, LTB
Most of the vaccinees showed a robust LTB-specific immune response after two ETVAX® doses, with GM increasing 22-fold in IgA and 15-fold in IgG antibody levels. Response against O78 LPS was lower: a 3.5-fold GM increase in IgA and 2.1-fold in IgG. The placebo recipients showed no significant increase in the mean antibody levels against either LTB or O78 LPS; the response magnitudes and frequencies are shown in Levels of IgA and IgG antibodies against LTB (A, B) and 078 LPS (C, D) before (pre) and after (post) administration of two doses of ETVAX® or placebo. Antibody levels were measured by MSD electroluminescence and are presented as GM ± 95% CI.