Author contributions
P.H.
L.M.S. conducted aspects of study visits, participated in data analysis, manuscript writing and editing, and conceptualization of experiments. E.G.S., E.V.P., L.B., and M.W. conducted aspects of study visits and participated in manuscript writing and editing. M.L. conducted aspects of study visits, participated in manuscript writing and editing, and participated in the conceptualization of experiments. P.S.H. is the study statistician and is responsible for the study analytic plan, participated in all study analyses, and participated in manuscript writing and editing. C.A.E. conducted aspects of study visits, participated in manuscript writing and editing, and conceptualized elements of the experimental design employed in this manuscript. From Scioto Biosciences: S.A. conceptualized elements of the experimental design and formulated the protocol, reviewed the data and participated in data analyses, and contributed to the manuscript writing and review. J.T., K.M., M.H., P.H., and K.W. participated in data analysis, manuscript writing and editing.