3.1. Samples
dizziness
EVENTS
Due to unforeseen events (dizziness and personal appointments), a total of four plasma and two saliva samples could not be taken. Only five (0.833%) of a total of 600 sampling times (50 per subject) were outside the targeted time interval. The largest time deviation was 7 min, while the shortest deviation was 2 min. Thus, more than 99% of the samples were taken within the scheduled time interval. No special relevance was attributed to these five samples, and they were analyzed like the other samples. One saliva sample and one plasma sample were not evaluable due to the analytical failure of the LC–MS/MS system.