Authors’ contributions
LHL and MZ designed the study.ZRY, LJC, SJZ, LXZ,ML, HL and LZ performed the experiments; LJC collected the data.ZRY, LJC and SJZ were involved in the data analysis; ZRY, LHL and MZ prepared the manuscript; HL and LZ reviewed the literature;LXZ and ML edited the manuscript; LHL and MZ per-formed the final review and all authors read and approved the final manuscript.