Treatments and monitoring of hemodynamic parameters
The treatments were performed as described in our previous article [Sedation/analgesia was achieved with either midazolam (0.2 mg/kg/h) and a non-narcotic analgesic or with neuroleptanalgesia (droperidol 25 μg/kg/h and fentanyl 1.0 μg/kg/h). Vecuronium (0.05 mg/kg/h) or pancuronium (0.05 mg/kg/h) was also used during the body temperature control phases, as required.Each patient’s hemodynamic status and intracranial pressure (ICP) were monitored, with the aim of maintenance at the following levels: mean arterial pressure (MAP) > 80 mmHg, ICP < 20 mmHg, cerebral perfusion pressure (CPP) > 60 mmHg, cardiac index (CI) > 2.5 L/min/m