Definitions
sore throat, diarrhoea, nausea/vomiting, ’ disease, fever, COVID-19 disease, cough, infection, loss of taste or smell, tachypnoea, headache, lower respiratory tract disease, body/muscle pain, shortness of breath
SORE THROAT, INFECTION, DISEASE
Asymptomatic or pre-symptomatic infection was defined in the presence of a positive diagnostic RT-qPCR test for SARS-CoV-2 in a patient without symptoms of COVID-19 disease. ‘Mild’ disease was defined in the presence of a positive RT-qPCR test for SARS-CoV-2 in a patient with any COVID-19-related symptoms (e.g. fever, cough, sore throat, malaise, headache, body/muscle pain, nausea/vomiting, diarrhoea, loss of taste or smell) in the absence of tachypnoea, shortness of breath or abnormal findings on chest X-rays. ‘Moderate’ disease was defined in the presence of a positive RT-qPCR test for SARS-CoV-2 in a patient with evidence of lower respiratory tract disease as shown at physical examination (tachypnoea, shortness of breath) or abnormal findings on chest X-rays, with an oxygen saturation (SpO2) level of ≥94% measured by a pulse oximeter. Clinical improvement was defined as a reduction of two or more points in the 0–10 NRS of severity of symptoms [