Statistical analysis
The sample size was calculated based on the primary outcome measures with two-sided significance α = 0.05 and power = 0.8. Statistical analyses were performed by using SPSS (IBM SPSS Statistics 25). It was assumed that the productivity of cutting the membrane would be 3 optic discs/min in the 27G group and 2 optic discs/min in the 25G group, with a standard deviation of 1.2 disc/min in both groups, resulting in 45 eyes. Anticipating a 10% dropout rate, the final sample size was determined to be 25 participants in each group, for a total of 50 participants.All statistical analyses were performed with SPSS (IBM SPSS 25.0). The data with a normal distribution confirmed by the Shapiro‒Wilk test were described as the mean ± standard deviation and underwent a two-tailed t test between the two groups. Otherwise, the median (interquartile range) was used to describe the data, and the Kruskal‒Wallis test was used for comparison. For unordered categorical variables, proportion (%) was utilized, and the chi-square test/Fisher’s exact test was suitable for comparison between groups. Statistical analyses of patients’ BCVA and IOP in different periods were performed using generalized estimating equations (GEEs). P values less than 0.05 were considered to indicate statistical significance.