1 Introduction
deaths
VIRUS, INFLAMMATION, ADHESION, CORONAVIRUS, SEVERE ACUTE RESPIRATORY SYNDROME
A novel coronavirus was first reported in December 2019 and declared an international pandemic by the World Health Organization (WHO) on March 11, 2020. Approximately, 18–19 months later, more than 250 million cases have been confirmed resulting in over 5 million deaths [COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a single-stranded, positive-sense RNA virus belonging to a group of Antiplatelet therapy has provided another avenue of great interest to reduce platelet adhesion and aggregation, which is a major consequence of COVID-19 induced renin-angiotension system (RAS) activation [Utilization of a therapy that can simultaneously intervene along multiple pathways (i.e: viral replication, inflammation, vasoconstriction, and coagulation) may provide an important mechanism to improve patient outcomes. One particular agent, Thus, we hypothesized that 