Metabolic profiles
SD
REGRESSION, INSULIN SENSITIVITY
NAC significantly decreased HOMA‐IR (β −0.33; 95% CI, −0.65, −0.009; Means (± SD) of metabolic biomarkers at baseline and after the 12‐week intervention in outpatients with SUD under MMT
Abbreviations: FPG, fasting plasma glucose; GSH, total glutathione; HOMA‐IR, homeostasis model of assessment‐insulin resistance; HDL‐cholesterol, high density lipoprotein‐cholesterol; Hs‐CRP, high sensitivity C‐reactive protein; LDL‐cholesterol, low density lipoprotein‐cholesterol; NO, nitric oxide; QUICKI, quantitative insulin sensitivity check index; VLDL‐cholesterol, very low density lipoprotein‐cholesterol; TAC, total antioxidant capacity; MDA, malondialdehyde.“Outcome measures” refers to the change in values of measures of interest between baseline and week 12. β (difference in the mean outcomes measures between treatment groups [NAC group = 1 and placebo group = 0]).Obtained from multiple regression models.