Introduction
DISEASE, INFLAMMATORY DISEASE
Corticosteroids are an effective treatment for many autoimmune and inflammatory diseases; however, there is a significant minority of patients across conditions who respond poorly [Metabolomics provides a powerful yet unbiased approach for identification of disease specific biomarkers of therapeutic responsiveness [Over the course of the three-year study, the MGTX clinical trial collected sera along with the Quantitative MG Score (QMG), MG-Activities of Daily Living (MG-ADL), and Minimal Manifestation Status (MMS). Major challenges for our investigation, and MG clinical research in general, is that the QMG and MG-ADL, despite validation and use as primary outcome measures, only show moderate correlation with each other [