Statistical analysis
LUNG METASTASIS, EVENT, BONE METASTASIS, EVENTS, LIVER METASTASIS
Given an accrual period of 12 months, a maximum follow-up time of 18 months, and a two-sided significance level of 0.05, 34 patients with 28 events were allowed detecting an increase of PFS from 2.8 months [Descriptive statistical analyses were mainly used. For PFS and OS, patients without document event were censored at last follow-up. The Kaplan-Meier method was utilized to estimate the median PFS and OS, as well as the 95% confidence interval (CI). Subgroup analysis was conducted by liver metastasis, lung metastasis, bone metastasis, prior taxane therapy, prior anthracycline therapy, and prior platinum therapy. Statistical analysis was performed using SPSS version 25.