Interventions
PD
APPENDIX
We selected 4 stool donors according to strict screening based on previously reported criteria.Sixteen capsules of FMT or placebo were taken orally by participants at once in the morning on an empty stomach, all subjects received either FMT capsules orally or placebo capsules once a week for 3 consecutive weeks. The appearance of FMT and placebo capsules was indistinguishable, and all capsules were taken at the hospital to ensure that participants were unaware of the content. Subjects in both groups maintained the original medication for PD before enrollment and maintained the regimen during the whole trial. Moreover, medical guidance helped them to maintain a healthy diet and rest schedule, details of dietary guidance and precautious of FMT are presented in the Supplementary Appendix.