D2 transmission in the fronto-striatal pathway
PD
A third finding is that D2 receptor activation can downregulate the striatal activity for maintaining (but not manipulating) sequences. This finding is compatible with our previous results. First, the striatum is hypo-activated in PD patients medicated with D2/3 receptor agonists and levodopa [D2 receptors are abundant in the striatum [The role of striatal D2 transmission might differ in sequential 