Discussion
Recent studies reported high prevalence of PA (29.1%) in patients with resistant hypertension (Second, in our study the total control rate of SBP <120 mmHg was 34.0% (17/50 patients), with greater representation of patients in the low, compared to the normal, sodium group (48.0% Changes in PRA following reduced sodium intake may be beneficial for IHA. Hundemer et al. (In conclusion, reducing dietary sodium was effective in lowering BP and raising serum potassium in patients with IHA who were maintained on low-dose antihypertensive medications without potassium supplementation. These effects were more pronounced in participants consuming 50 mmol, rather than 100 mmol, sodium per day over the trial’s duration. Specifically, in the low-sodium group (50 mmol/d sodium) 44.0% of patients had normal BP (<120/80 mmHg) and 32.0% of patients had normal serum potassium (3.5–5.5 mmol/L) at the end of the trial. In addition, the low-sodium diet was associated with better BP control in female IHA patients.There are some limitations in our study. First, as it lasted only 2 weeks, potential long-term effects of the low-sodium diet on IHA need to be further explored. Second, excessive aldosterone concentrations persist after adopting a low-sodium diet, an issue that may be adequately addressed by low-dose MRA treatment.