Statistical analysis
Quantitative data without a normal distribution were analyzed using the 2-tailed non-parametric Mann-Whitney U test. The 2-tailed Fisher’s exact probability test was used for bivariate analyses. Cumulative survival was plotted using the Kaplan–Meier method, and differences were compared using the Log-rank test. Statistical analyses were performed using JMP Pro, version 16.0.0 (JMP, Tokyo). P values <0.05 were considered to be significant.