Study procedures
ICH, diabetes
DIABETES
The ADREM study (Adjustment of insulin Degludec to Reduce post-Exercise (nocturnal) hypoglycaeMia in people with diabetes) was an open-label, randomised controlled, three-way crossover study, conducted in accordance with the principles of the Declaration of Helsinki, the Medical Research Involving Human Subjects Act and applicable International Conference on Harmonization (ICH) Good Clinical Practice guidelines. The study was approved by the local ethics committee and national competent authority. All participants gave their written informed consent before any study-related activity was performed.