Context
Claudia
DELAYED PUBERTY
Edited by: Adilson Marques, University of Lisbon, PortugalReviewed by: Claudia Giavoli, University of Milan, Italy; Gary Butler, University College London Hospitals NHS Foundation Trust, United KingdomThis article was submitted to Pediatric Endocrinology, a section of the journal Frontiers in EndocrinologyThe use of testosterone enanthate (TE), 50–75 mg intramuscularly (i.m.)/month, for the treatment of boys with delayed puberty or slow progression to induce puberty is the standard of care (SoC) in Sweden. This treatment is empirical and has not been scientifically evaluated. Replacement therapy in hypogonadal boys/young men in Sweden after induction is mainly performed with testosterone undecanoate (TU), 1,000 mg/3 months. TE is only available on license. TE was deregistered in Sweden in 2006. Therefore, this study was initiated to compare the two products.