4.6. Strengths
depression, psychiatric, anxiety
The strengths of the study are (1) the randomized, double-blind, and placebo-controlled study design, including a thorough and reliable psychiatric assessment and clearly defined inclusion and exclusion criteria; (2) the inclusion of standardized and internationally validated self-rating questionnaires; (3) the assessment of several important psychological factors such as depression, anxiety, and subjective sleep; and (4) the three time-points.