2. Methods
To evaluate the effectiveness of Equation (2), we conducted a series of in silico trials using the T1DMS approved by the Food and Drug Administration, which allows the evaluation of 33 virtual patients under multiple scenarios. Our study involved several experiments with different CHO estimation errors, both within and outside the calculated safe range for each patient. Subsequently, we compared the glycemic data obtained from these scenarios with the data collected in a control scenario, where there was no discrepancy between the actual CHO content and the patients’ estimations.