Discussion
muscle inflammation, TNF-α, muscle damage
INFLAMMATION, OXIDATIVE STRESS, MUSCLE INFLAMMATION
Both animal and human studies have shown that oral supplementation with garlic can contribute to reduced oxidative stress and inflammation. The benefits of garlic may be due to the flavonoids and sulfur compounds it contains [It’s well established that high levels of oxidative stress during exercise may increase muscle inflammation and damage, leading to underperformance. Thus, reducing systemic oxidative stress during exercise would be an important physiological factor in the performance of endurance exercise [The results of the present study showed that 4 weeks of garlic extract supplementation significantly delayed the inflammatory index TNF-α induced by exercise. We speculated that IL-6 is likely involved in the process (It has been shown that important physiological biomarkers for maintaining high-intensity endurance performance include inflammatory-related factors IL-6 and TNF-α, and muscle damage factors CK, LDH, and UA released from skeletal muscle cells [