Grading of neuropathy severity
multiple myeloma, Toxicity
MULTIPLE MYELOMA
We established a summary report form for our study patients. This report form included 4 parameters (sensory and motor function, QST, electrophysiology) which were each defined as abnormal or normal. The criteria for an abnormal finding are shown in Table Criteria for abnormal findingClassification of severity grades*Based on posology modifications in Phase II and III multiple myeloma studies and post marketing experience. Grading based on NCI Common Toxicity Criteria CTCAE v 4.0**Instrumental ADL: refers to preparing meals, shopping for groceries or clothes, using telephone, managing money, etc.***Self-care ADL: refers to bathing, dressing and undressing, self-feeding, using the toilet, taking medications, and not confined to bed