Ethics approval and consent to participate
All methods in this trial were carried out in accordance with the Declaration of Helsinki and its later amendment. This study was approved by the Institutional Review Board of Seoul National University Hospital, Seoul, Republic of Korea (approval number: H-1811-121-990). This trial was registered at the Clinical Research Information Service (CRIS) of Republic of Korea prior to the beginning of the trial:KCT0003885 (registration date 03/05/2019). Written informed consent was mandatory and obtained from all participants.