Authors’ contributions
The authors read and approved the final manuscript. JS, YTR, NNX, and PLW contributed equally to this work. JS, NNX, YTR, and PLW had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: HC, JS, NNX, YTR, PLW, NL, KY, SLA, PK, and HJZ. Acquisition, analysis, or interpretation of the data: HC, YTR, NNX, PLW, SLA, PK, HJZ, and JS. Drafting of the manuscript: JS, NNX, YTR, PLW, HJZ, and HC. Critical revision of the manuscript for important intellectual content: HC, YTR, NNX, HJZ, and JS. Statistical analysis: HC, NNX, YTR, PLW, SLA, PK, HJZ, and JS. Administrative, technical, or material support: SL, QYH, YZ, YZL, JLS, WJM, BC, XWZ, XMC, YQL, ZYL, GBD, ZZ, YQW, WHW, JS, HJZ, and HC. Study supervision: JS, HJZ, and HC. 