Data collection
interstitial cystitis, diabetes
INTERSTITIAL CYSTITIS, HYPERTENSION, PCT, DIABETES
Patients’ clinical and laboratory data were obtained from electronic medical records. This data included gender, age, body type, smoking history, drinking history, BMI, and basic medical history (hypertension, diabetes, etc.), as well as levels for the following indices: P2X3R, NGF, TrkA, urinary leukocyte, C-reactive protein, neutrophil count, erythrocyte sedimentation rate, and procalcitonin (PCT). The positive expression data of P2X3R, NGF, and TrkA were observed as brown particles stained light yellow to deep brown in the nucleus under a microscope.The scoring method for the proportion of positive cells was as follows: record 0 points if the proportion was less than 5%; record 1 point if it was between 6%-25%; record 2 points if it was between 26%-50%; record 3 points if it was between 51%-75%; record 4 points for values between 76%-100%. The scoring method based on color was as follows: 0 points for no color; 1 point for light brown/yellow; 2 points for deep brown/yellow; 3 points for brown/brown. The two scores were then multiplied together to obtain the final score. A score of 0–1 points was recorded as negative (-), 2–4 points as weakly positive ( +), 5–8 points as positive (+ +), and 9–12 points as strongly positive (+ + +) (See Figs. Immunohistochemical display of CD117 expression in interstitial cystitisImmunohistochemical display of P2X3 receptor expression in interstitial cystitisImmunohistochemical display of NGF expression in interstitial cystitisImmunohistochemical display of TrkA expression in interstitial cystitis