2.2. Clinical Efficacy on Skin Hydration and Transepidermal Water Loss (TEWL)
During the study, noninvasive biophysical parameters of the skin, including those measured from Corneometer, Tewameter, Cutometer, Mexamter, and Ultrascan UC22, were measured at baseline and 3 weeks after the initiation of treatment (end of study). The skin hydration measured by Corneometer showed a significant increase from 63.3 ± 9.9 to 70.8 ± 8.3 A.U., before and after the 3-week treatment with the test product; the control side showed a mild increase in skin hydration from 63.0 ± 10.1 to 64.1 ± 10.5 A.U. (