4. Discussion
inflammation, asthma
INFLAMMATION, ASTHMA
In this To our knowledge, this is the first analysis that describes the efficacy of a biologic that targets underlying type 2 inflammation by baseline neutrophil count in patients with asthma. Within the spectrum of asthma, elevated neutrophils can occur with or without type 2 inflammation. In a cluster analysis of patients in the SARP program, type 2 asthma patients with severe asthma who had the poorest lung function, frequent hospitalization, and uncontrolled symptoms despite high-dose oral corticosteroid use also had elevated blood neutrophils [One limitation of the current analysis is that it was performed 