1. Introduction
bone disease, Osteoporosis, osteoporosis
BONE DISEASE, CHRONIC INFLAMMATION, INFLAMMATION, OSTEOPOROSIS, LITTLE, OSTEOPOROSIS
Little is known about the inflammatory potential of diet and its relation to bone health. This cross-sectional study examined the association between the inflammatory potential of diet and bone-related outcomes in midwestern, post-menopausal women enrolled in the Heartland Osteoporosis Prevention Study (HOPS) randomized controlled trial. Dietary intake from the HOPS cohort was used to calculate Dietary Inflammatory Index (DIIAs the most common bone disease among adults, osteoporosis is a major public health concern, affecting approximately 54 million people in the United States and 200 million worldwide [There are many lifestyle modifications, including diet, known to aid in the prevention and management of osteoporosis. Traditional bone-related nutrients including vitamins D and K, calcium, and magnesium, are known to play significant roles in the protection and promotion of bone health [The association between dietary patterns and bone health may also be related to the inflammatory effect of diet on bone health. Chronic inflammation stems from a variety of sources, including diet, and is associated with a deleterious effect on bone health [While diet plays a key role in modulating inflammation, little research has been performed utilizing a quantitative measure of the overall effect of diet on inflammatory potential and its relation to bone health in the prevention and management of osteoporosis. Thus, the objective of this study was to determine the relationship between the inflammatory potential of diet, as measured by the DII, and bone-related outcomes of midwestern post-menopausal women screened for enrollment in the Heartland Osteoporosis Prevention Study (HOPS) [