Closed-loop insulin delivery system
The closed-loop app (CamAPS HX, CamDiab) involves the Cambridge adaptive model predictive control algorithm (HX software v.0.3.71) on an Android smartphone, which receives data from the continuous glucose monitor (Dexcom G6, Dexcom) and directs insulin delivery via the insulin pump (Dana Diabecare). The closed-loop app is initiated using participants’ total daily insulin dose and body weight. Every 8–12 min, in response to the sensor glucose data, the algorithm calculates an insulin infusion rate and communicates this wirelessly to the insulin pump. Sensor glucose and insulin data are automatically uploaded to the Diasend (