Author contributions
AHF
USZ, GX, KI-M, and MNS were responsible for the study concept and design. MNS, USZ, AHF, BM, and WHS contributed to data acquisition. KI-M produced the investigational medicinal products. SC, MNS, and USZ analyzed the data. MNS, GX, MHP, OCS, MNS, and USZ interpreted the findings. MNS and USZ drafted the manuscript. GX, MHP, OCS, and MNS provided critical revision of the manuscript. All authors reviewed and approved the final version for publication.