Outcomes
death, pain, ulcer, Cancer
ADVERSE EVENT, ULCER, ADVERSE EVENT, CANCER
The endpoint of this study was the incidence of OM. Oral assessment of each patient was performed by a single evaluator (M.Y.). The severity of OM was determined with reference to the National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0 as follows: Grade (G)1, asymptomatic or mild symptoms, intervention not indicated; G2, moderate pain or ulcer that does not interfere with oral intake, modified diet indicated; G3, severe pain interfering with oral intake; G4, life-threatening consequences, urgent intervention indicated; and G5, death. Adverse events were recorded regardless of whether they had a causal link to the mouthwash used during the study period.