Introduction
ideation, acute suicidal ideation or behavior, ®, psychiatric illness, depressive, psychiatric, depressive symptoms, MDD, Depression, ideation or behavior, disability
DISEASE, REMISSION
Depression is a devastating psychiatric illness that is a main cause of disability worldwide [The presence of active suicidal ideation with intent in patients with MDD constitutes a psychiatric emergency requiring urgent treatment of the underlying disease (ie, MDD). Current standard practice for these patients frequently includes hospitalization to ensure close monitoring along with treatment of symptoms of MDD with an antidepressant medication and development of a comprehensive crisis management plan before discharge from inpatient care [In 2020, the U.S. Food and Drug Administration approved SPRAVATO® (esketamine [ESK] nasal spray), taken with an oral antidepressant, for the treatment of depressive symptoms in adults with MDD with acute suicidal ideation or behavior [Among patients with MDD and suicidal ideation or behavior, the incidence of suicide attempts during a major depressive episode is 21-fold higher than during remission and the length of time spent in a major depressive episode is a risk factor for suicide attempts [