Ethics statement
Cancer Center/Cancer
The study was performed in accordance with the Declaration of Helsinki and the International Conference on Harmonisation Good Clinical Practice guidelines. The study protocol was approved by the institutional review boards or ethics committees of all participating centers (the ethics committee of the leading clinical center was the Ethics Committee of National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College). All patients provided written informed consent before participating in the study. Patients received compensation as described in detail in the informed consent form.