Study design
This study was designed as a single-blind, randomized controlled trial. The study protocol was approved by the İstanbul Medipol University, Non-interventional Clinical Studies Ethics Committee with the date of October 2020. (Reference:10840098–772.02-E.58328). In accordance with the principles of the Declaration of Helsinki, all volunteer participants were informed about the study and their written consent was obtained before entering the study. This study was registered with ClinicalTrials.gov Identifier:NCT04759690. The study was carried out between December 2020 and December 2021.