End-of-fluid protocol criteria
diarrhea, oxygenWeight gain, hHypoxemia, loose or watery, HUS
The pathways will end when the at-risk window for developing HUS, or worsening HUS if present, has passed and this time point is defined by:Platelet count is > 50 × 10Platelets have increased by ≥ 5%* (in the absence of transfusion) since preceding test ANDAbsence of diarrhea (loose or watery stool) × 24 h AND ≥ 5 days since the onset of diarrhea*If >10 days since the onset of diarrhea, up to a 5% decrease in platelet count since preceding test is acceptable.In addition, the fluid pathways should no longer be followed in children meeting any of the following criteria:Decision to initiate RRTAnuria for ≥ 12 hHypoxemia requiring supplemental oxygenWeight gain > 15%Hypertensive emergencyIf 