4.3. Statistical Analysis
Case number estimation was conducted via G-Power. The statistical analyses were carried out with the statistical software SPSS (SPSS 23 Inc., Chicago, IL, USA). Graphs were processed using GraphPad Prism (GraphPad Prism 5, San Diego, CA, USA). For statistical references, baseline mean values were taken and analysed for normal distribution by Kolmogorov–Smirnov tests before further analyses. In addition, data were analysed using paired Student’s Unless otherwise stated, all data were expressed as mean and standard deviation (SD). A 