Dual-energy X-ray absorptiometry (DXA) substudy
SECONDARY
Look AHEAD was also designed to examine secondary outcomes including areal BMD changes. In a preplanned substudy, total hip, lumbar spine, and whole body DXA scans were obtained at baseline, year 1, year 4, year 8, and at the observational visit which occurred 12.6 – 16.3 years after randomization (year 12–16) at five clinical centers (Baton Rouge, Boston, Houston, Los Angeles, and Seattle). This paper extends the BMD findings previously published to the year 8 and year 12–16 visit [Consort diagram for the Look AHEAD DXA substudy participants