Administration of drugs
infection
INFECTIOUS DISEASES, INFECTION, SARS-COV-2 INFECTION, GROUP B
After confirmation of participants’ contact to a laboratory-confirmed SARS-CoV-2 infection, participants were classified into two groups according to their type of exposure to SARS-CoV-2, e.g. Group A participants with continuous exposure to COVID-19 in which potential contact to SARS-CoV-2 infected individual was not blocked by removing or eliminating the source of infection in the site, and Group B participants with one-time exposure in which contact to SARS-CoV-2 infected individual was immediately blocked by managing study participants in isolation facilities for highly infectious diseases.For the purpose of PEP against continuous exposure to COVID-19, Group A participants were administered SA58 or placebo on every exposure day according to the recommended administration schedule and stopped administration three days after the source of infection had been eliminated or removed from the study site (e.g. all SARS-CoV-2 infected individual in the site had no symptoms and had negative RT–PCR testing results of SARS-CoV-2 for the last two consecutive days); for the purpose of PEP against one-time exposure in which the contact to the SARS-CoV-2 infected individual was immediately blocked, each participant was administered SA58 or placebo for a maximum of three days according to the recommended administration schedule.