Participant recruitment
retinopathy, retinal necrosis, AIDS-related CMVR, ketchup retinopathy, retinal vasculitis, CMVR, haemorrhages
RETINOPATHY, INFLAMMATION, RETINAL VASCULITIS, HAEMORRHAGES
Fifty patients were randomly divided into a low-dose group (ganciclovir 0.4 mg/0.1 mL per week, n = 25) and an intermediate-dose group (ganciclovir 1.0 mg/0.1 mL per week, n = 25) after diagnosis with CMVR. These random allocations were concealed from the subjects and the investigators to prevent bias. The inclusion criteria were that patients were first diagnosed with AIDS-related CMVR and were at least 18 years old. CMVR diagnosis was based on wide-angle fundus photographs showing the characteristic retinal changes. These changes comprise minimal to moderate anterior and vitreous inflammation, retinal necrosis with haemorrhages and retinal vasculitis with yellow–white lesions, also known as “pizza pie retinopathy” or “cottage cheese with ketchup retinopathy” [