Independent prognostic values of baseline parenclitic indexes to predict 6-month outcome
end-stage liver disease
REGRESSION
Multivariate Cox regression was performed to assess whether parenclitic indexes that individually predicted 6-month mortality had a prognostic value independent of age and MELD. Parenclitic deviations along the WCC-CRP axis (hazard ratio, 95% CI = 1.112, 1.053–1.174) and Bil-WCC axis (hazard ratio, 95% CI = 1.062, 1.017–1.108) significantly predicted outcome independent of age and MELD of patients at trial entry (Table Prognostic values of parenclitic indexes independent of age and MELD at admissionThe bold entries indicate parenclitic indexes that significantly predict survival.δ, deviation along an axis; Alb, serum albumin; Bil, total bilirubin; CRP, C-reactive protein; HR, heart rate; INR, international normalized ratio; MELD, model for end-stage liver disease; Na, serum sodium; WCC, white cell count.The results of a parenclitic network analysis of a split sample (randomly selected patients) extracted from the study population showed similar correlation network maps of biomarkers (see Supplementary Figures S1 and S2, Supplementary Digital Content, 