3.2.8. Stratified Analysis
hoarseness
A stratified analysis was performed to reveal the relationship between the condition of the immune system and the effects of LG2055. It was expected that the immunostimulatory effects of LG2055 may be observable especially in immune-weakened participants. The salivary sIgA secretion rate at 0 week was used to subdivide the participants. The 112 participants (57 in the LG2055 group and 55 in the Placebo group) who showed salivary sIgA secretion rates under the PPS average (110.3 μg/min) were regarded as immune-weakened participants and selected for the stratified analysis. No significant between-group differences were observed in the background characteristics of these participants.In comparison with the placebo group, CD86 expression was significantly higher in the LG2055 group at 12 weeks. In addition, HLA-DR expression in the LG2055 group tended to be higher than that in the placebo group at 12 weeks (Moreover, the daily physical questionnaire survey results indicated that the LG2055 group included a significantly higher ratio of “without symptoms” for runny nose, plugged nose, sneezing, hoarseness, and chill than the placebo group in this stratified analysis (