AOC3 activity relative to baseline.
Mean AOC3 activity relative to baseline versus time curves after once daily administration of 1 mg, 3 mg, 6 mg or 10 mg BI 1467335 or placebo for up to 85 days (whole profile days at Day 1, 28 and 84; FAS). Error bars show standard deviation from the mean. Source data are provided as a Source Data file. Dotted line indicates 20% residual AOC3 activity relative to baseline. AOC3 amine oxidase copper-containing 3, FAS full analysis set.