5. Conclusions
ADHESION, HYPERCHOLESTEROLEMIA, COMPLICATIONS
The present study indicates possible beneficial effects of daily intake of black garlic. Consumption of black garlic improved the ratio of TC/HDL-cholesterol in healthy subjects and there was a tendency to decrease in the atherogenic index of apolipoproteins. Decreased levels observed of endothelial adhesion molecules, VCAM-1 and ICAM-1, may indicate a better prognosis for complications of hypercholesterolemia. However, long-term studies are needed to confirm the relevance of these findings, examining the effect in a cohort at increased cardiovascular risk. It is also necessary to evaluate the bioavailability of low molecular weight bioactive compounds from black garlic, in order to correlate their presence with the observed biological effects.