Introduction
varicella zoster, death, illness, encephalitis, Encephalitis, aetiologies, herpes simplex
VARICELLA ZOSTER, VIRUS, ENCEPHALITIS, ENCEPHALITIS, HERPES SIMPLEX
Encephalitis is a major cause of illness and death globally.Encephalitis is more prevalent among children than adults, with an estimated incidence of 4.0–12.6 per 100 000 person years for children in high-income countries.While there is good evidence for the efficacy of aciclovir in the management of encephalitis caused by herpes simplex virus and varicella zoster virus,IVIG is used successfully in other inflammatory and neurological conditions in childrenIn this study, we set out to establish if early IVIG treatment, in addition to standard care, improves outcomes for children with encephalitis of all aetiologies.