Intervention
The intervention stipulated three 60-minute aerobic training sessions (completed on bicycle ergometers) on separate days per week for 16 weeks at an exercise intensity of 60–80% of peak heart rate measured at baseline. A wrist-worn heart rate and activity monitor (Fitbit Charge HR; Fitbit, Inc.) was gifted to the participants who were encouraged to wear it daily. To track physical activity in the intervention group, activity from the wrist-worn activity monitor was tracked using the Fitabase data management platform and records kept of training sessions attended. The compliance threshold for the intervention was set at 80%, equivalent to 39 or more independent training sessions, with no more than 2 weeks between sessions. A compliant session was defined, 