Interpretation of the findings
In general, an average overall effect (absolute and/or relative risk reduction) is reported in randomized trials. However, for optimal individualized decision-making, personalization of the treatment effect is more informative. Although in this study all AF patients seem to benefit similarly from integrated AF care on a relative scale, the absolute effect was the greatest in patients with a high predicted all-cause mortality risk, this is in patients in whom many clinical variables from the CHA