Primary clinical endpoint
After a median follow-up period of 34 months, the PFS6 rate was 35% (95% confidence interval (CI), 13– 58%) in group 1 and 38% (95% CI 21–54%) in group 2. The median PFS was 3.7 (95% CI 1.8–7.8) and 3.6 months (95% CI 1.7–7.1) in group 1 and group 2, respectively. The Kaplan–Meier analyses are shown in Fig. 