Effect of aspirin treatment on lipid mediators among PWH
PWH
PWH were randomized to 12 weeks of either daily aspirin 300 mg, aspirin 100 mg or placebo and self-reported adherence to the intervention was high.Effect of aspirin on lipid mediator metabolomes among PWH.The mean fold-change and mean fold-change percent from baseline is shown for the three study arms for each lipid mediator metabolome. Analysis of variance were conducted to test the effect of the 100 mg and 300 mg dose of aspirin as compared to the placebo.We then repeated the above analyses for the individual lipid mediators. The difference noted above at the metabolome level for PG was mostly driven by PGE