Impact of 
reductions in blood pressure
Long‐term caloric restriction has been demonstrated to induce favorable cardiovascular effects, namely reductions in blood pressure and improved lipid profile (Fontana et al., Although, in the present study, using a short‐term 3‐day CR down to 590 kcal/d of intake we observed no significant changes in systolic, diastolic, or mean arterial blood pressure measured peripherally or estimated centrally at the aorta (Figure In terms of lipid profile, while longer term CR may induce reductions in total cholesterol, LDL cholesterol, triglycerides, and glucose with concomitant increases in HDL cholesterol, thereby improving the total/HDL ratio (Jakobsdottir et al., 