Statistical analysis
Statistical analyses were performed using GraphPad Prism 8.0.1 program package. A Shapiro−Wilk's test was used to test the normality of the variables. Normal distribution data are presented as mean ± standard deviation, non‐normal distribution data are presented as median with interquartile range. Categorical variables are presented as percentages and frequencies. Comparisons of the means of continuous variables were performed using unpaired Welch's 