Background
colorectal cancer, tumor, metabolic derangements, CRC, cancer death, cancer, deaths
CANCER, COLORECTAL CANCER, TUMOR
Globally, colorectal cancer (CRC) is the second leading cause of cancer death, accounting for an estimated 915,880 deaths in 2020 [Metabolic reprogramming is a hallmark of cancer. Accumulating evidence suggests that metabolic derangements provide abundant energy, nutrients, and redox requirements for tumor cells, which contributes to the occurrence and progression of tumor [Therefore, our study evaluated the prognostic values of seven preoperative serum liver enzyme markers. Considering the ability of a single serum biomarker may be insufficient, we incorporated significant serum liver enzyme markers and clinicopathological features to develop prognostic nomograms for a better individual CRC patient’s survival prediction.