2.3. Outcomes
AKI, nausea or vomiting, postoperative urinary retention, postoperative nausea and vomiting, hypotension, PONV, Hypotension, acute kidney injury
SECONDARY
The primary outcomes were the differences in HR and BP between the 2 groups during the study drug administration. Vital signs were measured at baseline after entering the operating room, every 2 minutes after drug administration for 30 minutes, and in the postanesthesia care unit (PACU).The secondary outcomes were the number of patients whose HR was < 50 bpm after the DEX loading dose infusion and the associated factors. The incidence of hypotension in the PACU, PACU length of stay (LOS), postoperative nausea and vomiting (PONV), postoperative urinary retention (POUR), time to first urination after SA, acute kidney injury (AKI), and postoperative hospital LOS were evaluated. Hypotension in the PACU was defined as a decrease in systolic BP to <20% of the baseline. PONV was defined as a complaint of nausea or vomiting for which antiemetic drugs were administered. POUR was defined as urine retention of ≥300 mL on clean intermittent catheterization while the patient complained of suprapubic discomfort.