The phenylalanine metabolism-related key gene MAOA played important role in sepsis
sepsis, septic
SEPSIS
Due to the enrichment analysis of differential metabolites and machine learning screening showing the significant role of phenylalanine in the progression of sepsis, we further investigated the role and regulatory mechanism of phenylalanine metabolism in sepsis. We analyzed transcriptome data from the GEO database. This dataset included 25 blood samples from healthy controls and 82 blood samples from septic patients. We identified differentially expressed genes (DEGs) between the sepsis and healthy control groups using a threshold of |log2FC|> 1 and The role of MAOA in sepsis rats. 