4. Randomization and concealment
Using the SPSS software (version 20.0), we conducted permuted-block randomization. This process involved a computer system that utilized an allotment list to generate random numbers in a 1:1 ratio. The block is set as 2. To preserve the research integrity and blinding, a statistician who was not part of the research team conducted the task. The results of the arbitrary sampling procedure were placed in prenumbered envelopes and stored at the research site until the completion of the study. Neither the research participants nor the patients/family members knew which treatment was being administered during the trial. Every single instance was meticulously documented. Next, we gathered data regarding the patient’s characteristics, past medical records, and relevant examination results.