6. Future Recommendations
ADVERSE EFFECTS, COLD
It is recommended to conduct multi-center trials involving a study population that encompasses diverse age groups and to employ methodologies that incorporate patient follow-up. This will lead to an improved comprehension of the efficacy and possible post-injection adverse effects of different anesthetic agents. Moreover, objective measures, like Electric Pulp Testing or Cold Testing using liquid nitrogen or ethyl chloride, should be utilized for more reliable results regarding complete pulpal anesthesia. Lastly, during the training of patients, it is recommended to perform the calibration tests and report the findings in the methods. 