Baseline analysis
ideation, neurotoxic
We performed Spearman correlations between peripheral inflammatory markers and kynurenine metabolites ratios indicating the progressive diversion of the KP towards the production of neurotoxic enzymes, in particular the KYN/TRP ratio, the 3HK/KYN ratio, the 3HAA/3HK ratio and the QUIN/3HK ratio. Correlations were corrected for multiple comparisons using Bonferroni. Then, with a Mann–Whitney test, we compared KP metabolites levels and ratios between patients with and without baseline suicidal ideation.