Detection method and prognosis
lung cancers, cancers, tumor
LUNG CANCERS, CANCERS, TUMOR
Table Characteristics of lung cancers detected in PLCO.n (%).Fisher’s Exact Test for Count Data with simulated p-value (based on 2000 replicates).There is evidence of stage shift when comparing the distribution of Stage I–IV cancers in the Screen group with the other three groups (p-value The variable Smoked is distributed differently across the four groups (Figure (Note also that the association between detection method and survival in univariate analysis does not necessitate that detection method will have independent prognostic value in a multivariate model after adjusting for tumor characteristics and other baseline risk factors. For example, the association between detection method and survival could be explained entirely by other variables such as stage (i.e., screen-detected cancers are more likely to be Stage I, which by itself has favorable prognosis). To investigate this issue, Figure 