Baseline Characteristics
depression, depressive symptoms
Among 171 included patients, 125 patients (73.1%) were randomized to the PIT (n = 63) or control (n = 62) group. A total of 14 randomized patients (11.2%) were excluded from the analysis because TCA treatment was not initiated due to early improvement of depressive symptoms or violation of the study protocol (At baseline, there were no differences between treatment groups with regard to sex, age, depression characteristics, CYP2D6 and CYP2C19 phenotype distribution, and type of TCA (