RESEARCH IN CONTEXT
PD
RENAL, HEMODYNAMIC INSTABILITY
Renal replacement therapy in children under 8 kg in PICU presents challenges with obtaining access, fluid measurement accuracy, and circuit volume. Improved technology is required.The unreliability of fluid balance control during dialysis or hemofiltration may cause hemodynamic instability in small babies.The NIDUS, a new hemodialysis and ultrafiltration device specifically designed for patients 0.8–8 kg, was compared with existing treatments with PD and continuous venovenous hemofiltration (CVVH).