Background
Aging societies worldwide are associated with an increase in the rate of polypharmacy, which is frequently characterized by the concurrent use of five or more medications [The risk of receiving PIM is also higher in NHR compared to older people living in the community [Drug management in NHR is a complex interprofessional six-step process that involves the collaboration of NHR (or their relatives/representatives), physicians (mostly family doctors), nurses, and pharmacists [NHR are more likely to get a PIM prescription when collaboration is unstructured [According to Donabedian, quality of care comprises two main aspects: 1. technical care—meaning the extent to which the provided care maximizes the health benefits of an individual without increasing risk (a valuation that is to be shared between the caregivers and the patient), and 2. the psychosocial interaction between caregiver and receiver [The HIOPP-3-iTBX study (HIOPP, primary care initiative to optimize patient safety in polypharmacy; iTBX, interprofessional toolbox) is the first cRCT on medication optimization in NH in Germany [