Statistical analysis
MINOR
Statistical analysis was performed based on the results obtained from 43 women (22 in the experimental and 21 in the control group) in a double-blinded study. The skin hydration and demographic features of women in these two groups revealed that at baseline, the groups were not statistically significantly different for any of the considered variables (A two-way repeated measure ANOVA was performed to evaluate the effect of TCA peel administration on HFUS skin parameters measured with DUBSkinScanner75 at four-time points compared to the control group. The obtained results are shown in Figures In the case of confirmed interaction, the differences between groups were assessed separately at individual time points. No interaction indicates that the differences between the group means did not change significantly over time - did not depend on the measurement time point. Each statistically significant effect was assessed in terms of its size, and minor effects, being clinically irrelevant, were not reported in this paper.Boxplots present the median, the first and third quartile, and the whiskers indicate the outliers range. Statistically significant differences are indicated with stars (*Thickness and intensities.Intensities.nLEP, nMEP, nHEP (entry echo layer).nLEP, nMEP, nHEP (upper dermis).nLEP, nMEP, nHEP (lower dermis).nLEP, nMEP, nHEP ratio, roughness, energy.Entropy, homogeneity.Correlation, contrast.