References
irritability, fatigue
CARD
Overview of experiment study timeline for the placebo (PL), low-dose (LD), and high-dose (HD) groups.Consolidated Standards of Reporting Trials (CONSORT) chart for the placebo (PL), low-dose (LD), and high-dose (HD) groups.Timeline of testing sessions. RHR represents resting heart rate, while BP represents blood pressure. Questionnaires included the Profile of Mood States, fatigue and eye irritability rating, side effects, and sleep quality. Cognitive function tests included the Berg-Wisconsin Card Sorting, Go/No-Go, Sternberg, and Psychomotor Vigilance Task tests.Berg-Wisconsin Card Sorting Test mean changes with 95% confidence intervals from Day 0, pre-game (Pre) values for the placebo (PL), low-dose (LD), and high-dose (HD) groups. Go/No-Go Task test mean changes with 95% confidence intervals from Day 0, pre-game (Pre) values for the placebo (PL), low-dose (LD), and high-dose (HD) groups. Sternberg Task Test mean Absent and Present Reaction Time changes with 95% confidence intervals from Day 0, pre-game (Pre) values for the placebo (PL), low-dose (LD), and high-dose (HD) groups. Psychomotor Vigilance Task Test changes with 95% confidence intervals from Day 0, pre-game (Pre) values for the placebo (PL), low-dose (LD), and high-dose (HD) groups. Light reaction test changes with 95% confidence intervals from Day 0, pre-game (Pre) values for the placebo (PL), low-dose (LD), and high-dose (HD) groups. Mean gaming performance Z scores and percent change from baseline with 95% confidence intervals in gaming performance.Profile of Mood State domain changes from baseline with 95% confidence intervals from Day 0, pre-game (Pre) values for the placebo (PL), low-dose (LD), and high-dose (HD) groups. 