Statistical analysis
The basic attributes of the participants were subjected to simple tabulation followed by statistical analysis. The differences between the endpoints at baseline and 3 months after enrollment were then calculated and used to compare the intervention and control groups. The Mann–Whitney U test was used for comparison. The number and content of interventions were tabulated. We used a personal computer with Microsoft Windows 8.1 operating system (Microsoft Corp., Redmond, WA, USA), and statistical analysis was performed using IBM SPSS Statistics ver. 21.0 software (IBM Corp., Armonk, NY, USA). The significance level was set at two-tailed p < .05. The intention-to-treat (ITT) analysis method was employed in this study.