Subgroup analyses
LUTS
No effect modification was found when including the ratio of storage to voiding LUTS at baseline as a continuous interaction term in the model of IPSS at 12 months (P=0.971). Similarly, distinguishing between those men who received the intervention via a study nurse (n=249) or a practice nurse or healthcare assistant (n=190) also showed no evidence of difference (P=0.387). Weak evidence of effect modification (P=0.094) was, however, found in relation to how intervention participants preferred follow-up by the clinical team (telephone=310; text or email=121), with those opting for contact by text or email showing a greater improvement compared with usual care than those opting for contact by telephone.