Statistical Analysis
cSCC lesions
Since this was an exploratory study, no sample size calculation was performed in advance. To obtain the incidence density in the baseline visit, the total number of biopsied-proven cSCC lesions observed during all the historical dermatologic follow-up was divided by the total number of person-years at risk before the inclusion. The time to T0 was calculated from the start of follow-up with the dedicated dermatology team that works regularly in partnership with the transplant center. In each subsequent yearly study visit, the total number of new lesions was divided by the number of person-years at risk in that year. A similar analysis was performed by stratifying the lesions by each severity criterion. The comparative analysis was performed using the Generalized Estimating Equations model with log-link function and Poisson distribution considering the period of exposure, which allows the incorporation of dependence among observations of the same patient. For all statistical tests, a level of 5% significance. Statistical analysis were performed using the STATA 17 statistical software. 