Patients
Pain, CRPS, pain
Eligible patients who fulfilled the inclusion criteria (CRPS 1 or 2 of the upper limb, duration ≥6 months, age ≥18 years, mean pain intensity ≥5/10, conventional therapies have been tried or continue without significant relief) were recruited from the Helsinki University Hospital Pain Clinic, Private clinics, and via advertisements to social media in a private CRPS patient group (Figure Flow diagram of patient enrollment.The study was approved by the Helsinki University Hospital Ethics Committee and was registered in the ClinicalTrials.gov (NCT04439669). All eligible patients signed the informed consent.