Follicular growth, fertilization and embryonic development
On the day of hCG administration, number of follicles larger than 16 mm and serum EFor all patients’retrieved oocytes, developmental outcomes were monitored during the first 2 days of culture. Comparing 47 G-CSF and 48 control patients with successfully retrieved oocytes, numbers of retrieved oocytes did not differ significantly but numbers of fertilized oocytes and day-2 embryos per retrieval were significantly higher in the G-CSF group than in controls (fertilized oocytes, 5.7 ± 3.7 Numbers of retrieved oocytes, fertilized oocytes, and day-2 embryos per successful oocyte retrieval (Embryo transfers were carried out at 2, 3, and 5 days after oocyte retrieval in 7, 22, and 18 G-CSF patients and in 9, 27, and 12 control patients, respectively. Distributions of ET days did not differ significantly between groups (chi-squared test). Oocytes from significantly more G-CSF patients proved suitable for embryo culture until 5 days after oocyte retrieval than did oocytes from control patients (57% [27/47] Developmental potentials of oocytes and embryos were significantly greater in the G-CSF group (Fig. Serum AMH concentrations significantly increased after G-CSF administration but significantly decreased in the same interval for controls (Fig. 