Exploratory moderator analyses
For the moderator variable ‘psychosocial training’, a significant interaction with ‘nasal spray’ was identified (Change in treatment responses according to the presence of concomitant psychosocial training. Visualization of changes from baseline in parent-reported social responsiveness (SRS-2 raw total scores) of the double-blind phase (phase I), separately for children receiving only the oxytocin (Direct comparisons showed that improvements in social responsiveness in the subgroup of children receiving the OT nasal spray in combination with psychosocial training (see Fig. For all the other assessed moderator variables (concomitant medication use, sex or parent-reported beliefs), no significant main effects or interactions with nasal spray were identified (all, 