Introduction
death
MYOCARDIAL INFARCTION (MI), ACUTE CORONARY SYNDROME, PROLIFERATION, INFLAMMATION, VIRAL INFECTION, EVENTS
Despite modern advances in therapy, myocardial infarction (MI) still carries a substantial risk of death or recurrent cardiovascular events [Immunosenescence is mainly linked to thymic involution and changes in cellular immunity as a response to pathogens, such as recurrent viral infections, throughout life [Lymphocyte proliferation can be enhanced in vitro by activating telomerase, a reverse transcriptase that typically counteracts telomere shortening at the end of chromosomes [We present the results from the Telomerase ACTivator to reverse Immunosenescence in Acute Coronary Syndrome (TACTIC) trial—the first randomized controlled trial investigating whether treatment with TA-65 for 12 months after MI reduces immune ageing and inflammation.