Study end points
PD, death, SD
DISEASE, RECURRENCE, SECONDARY
The primary end points were disease control rate (DCR), which was the proportion of patients achieving complete response (CR), partial response (PR), and stable disease (SD). The secondary end points included ORR, which was the proportion of patients achieving CR or PR; PFS, calculated from the date of study entry to progressive disease (PD) or death, whichever occurred earlier; OS, calculated from the date of study entry to death of all cause; and duration of response (DOR), which was the duration from initial CR or PR to PD or recurrence.