1. Introduction
hypophosphatemia, inflammatory bowel diseases, osteomalacia
HYPOPHOSPHATEMIA, INFLAMMATORY BOWEL DISEASES, FRAGILITY, IRON DEFICIENCY ANEMIA, OSTEOMALACIA
The association between intravenous iron substitution therapy and hypophosphatemia was previously reported in patients with iron deficiency anemia. However, the extent of hypophosphatemia is thought to depend on the type of iron supplementation. We hypothesized that the intravenous application of ferric carboxymaltose and iron sucrose leads to a different longitudinal adaptation in serum phosphate levels. In this open-label pilot study, a total of 20 patients with inflammatory bowel diseases or iron deficiency anemia were randomly assigned to one of two study groups (group 1: ferric carboxymaltose, The association between intravenous iron substitution therapy and hypophosphatemia was first reported in 1983 [Chronic hypophosphatemia can affect bone metabolism and cause changes in bone structure and microarchitecture, eventually leading to osteomalacia and bone fragility [As the extent of hypophosphatemia is thought to be dependent on the type of iron supplementation [