Circulating B-OHB levels
weight gain
The limit of detection for B-OHB for our measurement was 20 μmol/l and the range in the overall cohort was from 22.2 to 296.5 μmol/l. In the LC group, nine participants (17.0%) did not show detectable levels of B-OHB in their fasting blood. In the HC group, four participants (7.3%) had no detectable B-OHB levels (B-OHB concentrations and carbohydrate intake. (Given that the B-OHB concentrations at 28 weeks’ gestation were quite variable, we therefore investigated whether dietary intakes of other macronutrients were different between participants with B-OHB concentrations above and below the median of 65 μmol/l. There were no significant differences between the low (LB) and high (HB) B-OHB groups in routine dietary macronutrient intake, maternal BMI, age, blood pressure, gestational weight gain, infant birthweight or length, or in circulating maternal cholesterol or triglycerides (ESM Tables Differences in glucose and insulin between participants in the LB and HB groups. (