Endpoints and definitions
HFSR, Cancer
ADVERSE EVENT, SECONDARY, CANCER
The primary endpoint of the present, single-arm study was the incidence of regorafenib-associated grade 3 HFSR as assessed using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events v.4.0. The secondary outcomes were the incidence of all grades of HFSR, time to the development of HFSR of any grade, time to improvement from HSFR 