Limitations
arthritis
ARTHRITIS
The MOVE trial from which the data from the current study were drawn, and indeed the current study, are not without limitations. First, physical activity was measured by self-report at each timepoint rather than device-based measures, such as accelerometers. As such, recall bias and social desirability bias cannot be ruled out. Second, we drew on a subsample of the randomized participants in the MOVE trial who self-reported having arthritis, but we were not able to confirm the type or severity of their arthritis. Third, we applied the missing at random assumption and replaced missing values with LOCF. This may have led to the underestimation or overestimation of some of the associations identified.