WHAT THIS STUDY ADDS
ARIs, ARI, ’
VITAMIN D DEFICIENCY
‘D-Kids’ is the first randomised controlled trial (RCT) to evaluate vitamin D supplementation as a novel strategy for reducing early-onset ARIs among Australian First Nations infants. This study extends the best local and international evidence, implementing a practical weekly vitamin D dose over known high-risk period of both vitamin D deficiency and ARI. Importantly, this RCT will monitor vitamin D levels through pregnancy and infancy and determine whether supplementation impacts the paediatric immune response and the acquisition of respiratory pathogens.