Subgroup analyses of PFS with Isa-Kd vs Kd.
renal disease
RENAL DISEASE
CI confidence interval, d dexamethasone, eGFR estimated glomerular filtration rate, IMiD immunomodulatory drug, IRT Interactive Response Technology, Isa isatuximab, ISS international staging system, K carfilzomib, MDRD modification of diet in renal disease equation, PFS progression-free survival, PI proteasome inhibitor. *Prior treatment=last prior anti-myeloma regimen.Although the overall response rates were comparable between treatment arms (86.6% vs 83.7%), deeper responses were seen with Isa-Kd vs Kd in the ITT population: the sCR/CR rate was 44.1% with Isa-Kd vs 28.5% with Kd (odds ratio Isa-Kd vs Kd: 2.09, 95% CI: 1.26–3.48) (Fig. 