Outcomes
fever, throat, cough, Fever, Cough
SECONDARY
The time that took for a throat swab test for SARS-CoV-2 to become negative was the primary endpoint. The secondary endpoint is the time to clinical recovery (TTCR), defined by the time from the beginning of treatment to that the respiratory rate, fever, blood oxygen saturation become normal, and the cough is relieved, which lasts for at least 72 h. Fever is defined as oral temperature ≥37.1 °C, or axillary temperature ≥36.6 °C, or rectal temperature or ear temperature ≥37.8 °C. A normal respiratory rate is ≤24 times per minute (under indoor air). A normal blood oxygen saturation is >94% (under indoor air). Cough relief means the patient’s cough must be mild or no, according to the classification of “severe/moderate/mild/none”. Severe is frequent coughing, which seriously affects daytime life or seriously affects night sleep; moderate is also frequent coughing, but lightly affecting daytime life or lightly affecting night sleep; mild is occasional short-term cough or occasional night cough; none is no cough.