Methods
age-related cataracts, Diabetic Retinopathy, corneal astigmatism, ocular trauma, Johnson and Johnson Vision, lens opacities
IOL, DIABETIC RETINOPATHY, BILATERAL CATARACTS, PATHOLOGY, EYE
This prospective, randomized, and comparative controlled study included patients with age-related cataracts who underwent bilateral cataract extraction with phacoemulsification and IOL implantation with either an enhanced monofocal IOL (Tecnis Eyhance, ICB00, Johnson and Johnson Vision Care, Inc) (Group 1) or a standard monofocal IOL (Tecnis, ZCB00, Johnson and Johnson Vision Care, Inc) (Group 2). Both groups comprised of 25 patients and the diagnosis was made using the lens opacities classification system (LOCS) III.This study followed the tenets of the Declaration of Helsinki and was approved by the Institutional Review Board of Kangbuk Samsung Hospital (IRB File No. 2019–12-030). All study participants signed the informed consent before enrollment.Inclusion criteria were patients aged 50 years or older at time of study enrollment, who underwent surgery of fellow eye 1 week after surgery of the first eye, showed postoperative visual potential of 20/25 or better, and had pre-existing corneal astigmatism of less than 1.25 D. Exclusion criteria were: any general condition that may affect the surgical outcomes and a history of ocular trauma, surgery, or pathology that may limit the visual function.All patients received preoperative ophthalmic examination including mesopic (3 cd/All surgeries were performed by one surgeon (CYC): under topical anesthesia, a 2.2 mm corneal incision was made, followed by manual capsulorrhexis and phacoemulsification. All IOLs were implanted in the bag. Postoperative target refraction was determined as the lowest myopic value after emmetropia using the Haigis formula in IOL calculation.Follow-up examinations were performed at 1-week, 1-month, and 3-months after implantation of the second IOL. Main outcome measures included visual acuities, monocular and binocular defocus curves, contrast sensitivity testing (CST), reading speed test, and patient questionnaires. UDVA, UIVA at 66 cm, and UNVA at 40 cm were measured using the Early Treatment Diabetic Retinopathy Study charts (ETDRS; Vector Vision, Ltd., Greenville, OH, USA). Uncorrected monocular and binocular defocus curves were obtained for distance vision with the ETDRS charts at intervals of 0.50 spherical D from − 4.00 to + 1.00 D. CS was measured at 3.0, 6.0, 12.0, and 18.0 cycles per degree (cpd) under photopic (85 cd/mPatients' subjective satisfaction was analyzed using the quality of vision (QoV) and vision-related quality of life (QoL) questionnaires both preoperatively and 3-month postoperatively, while spectacle independence was assessed using the 25-item National Eye Institute Functional Questionnaire (NEI VFQ-25).The binocular reading speed at 40 cm was measured at 3-months postoperatively as described by the Korean Reading Speed Application tester [Statistical analysis was performed using the SPSS software (Version 24.0: SPSS, Inc). Intergroup comparisons of monocular and binocular visual outcomes were performed with the independent two sample t-test and Pearson’s chi-square test. The Mann–Whitney U test was used to compare quantitative variables (such as refraction) and reading speed. The 