METHODS
HIV viral suppression
WEST
This study was a randomized double‐blind clinical trial involving 30 patients treated with ART at West Medical Center, Tehran, Iran.According to World Health Organization (WHO) criteria, patients who have received standard first‐line therapy ART for 1 year or more are referred for evaluation of second‐line therapy ART if they have CD4 decline to levels before ART, CD4 decline to less than 50% of peak at baseline, or failure to achieve CD4 levels above 100 c/mmBefore the study began the patients received at least 48 weeks of ART (first line or second line) who had experienced immunological failure despite HIV viral suppression.Patients were divided into two groups of 15. Group (B) received two probiotic capsules daily with a colony count of 10⁹ CFU per capsule containing seven strains (including By the end of Month 3, patients were tested for CD4After a 1‐month washout period, the participants who had received probiotics were switched to a placebo, and the participants who had received placebo were given probiotics for 3 months, and they were examined for CD4