Intervention adherence and adverse events
ADVERSE EVENTS, ADVERSE EVENT
Participants were asked to complete a physical activity diary (for prescribed exercises only) during each week of the training phase to determine adherence to the exercise protocol. Diaries from the previous week were returned to the study center in subsequent supervised exercise sessions. At 12- and 24-week appointments, participants returned any unused tablets, which were counted to estimate adherence to the supplementation protocol.Information about adverse events was collected during testing sessions and weekly exercise sessions. Any untoward medical occurrence in participants that required some form of treatment was considered an adverse event, irrespective of whether it was thought to be related to the interventions.