Introduction
tumors, HGPC, Prostate
TUMORS, BENIGN PROSTATIC HYPERPLASIA (BPH), PROSTATE, PROSTATE
PSA screening allows for early detection of tumors but is very non-specific and elevated PSAs are often the result of benign prostatic hyperplasia (BPH). Additionally, PSA testing enables a higher detection rate of indolent tumors, as the PSA test is not able to discriminate high-grade PC (HGPC) [The ExoDx Prostate, EPI test, is a urine exosome gene expression assay that does not require a pre-collection digital rectal exam (DRE) to make informed prostate biopsy decisions. The EPI test performance has been extensively studied previously [