Trial Procedures
adenomyosis
ADENOMYOSIS, ADVERSE EVENTS
After 4 weeks of screening, patients with adenomyosis were randomly assigned at a 1:1 ratio to receive mifepristone (10 mg) or placebo orally once a day for 12 weeks during the double-blind period. Regular trial visits were performed every 4 weeks and lasted until 4 weeks after treatment. The efficacy of treatment, adverse events, and safety assessments were all recorded throughout the trial. Patients were not allowed to use other drugs or treatment methods that affect the efficacy evaluation. From an ethical point of view, it is considered acceptable for patients to receive analgesics in placebo-controlled trials, and the use of indomethacin suppositories is recommended only to avoid trial bias.