Study design
INFLUENZA
This is a randomized, double-blinded, double-dummy, parallel control of positive drug, multi-centre clinical study. The trial will be conducted in ten centers at China and collaborate with hospitals including Children’s Hospital Of Soochow University, Anhui Provincial Children’s Hospital, Qilu Children’s Hospital of Shandong University, Tianjin 4th Centre Hospital, Renmin Hospital of Wuhan University, Hebei Maternity&Child Healthcare Hospital, the Second Affiliated Hospital of Jiaxing University, the First Hospital of Hunan University of Chinese Medicine, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine and one undetermined. The trial obtained ethical approval from Ethics Committee of The First Affiliated Hospital of Henan University of Chinese medicine (approval number: 2019HL-137-01), and will be conducted according to Participants with influenza in Children will undergo a standardized baseline evaluation before treatment. All included participants are randomly divided into two groups: experimental group and control group.The experimental group receives RDN + Oseltamivir phosphate granule simulants and the control group receives Oseltamivir phosphate granules + RDN simulants. After five days of treatment with evaluation every 24 h, the efficacy and safety of two groups will be evaluated. The study design is shown in Fig. 
Flow diagram