Blood samples
infection, hemolysis, sinusitis
INFECTION, HEMOLYSIS, SINUSITIS
Clinical laboratory tests were drawn at fasting state at baseline, 3-month follow-up, and 6-month follow-up and included; leukocyte concentration, MCH, platelets, mean cell [erythrocytes] volume (MCV), erythrocyte concentration, erythrocyte volume fraction (EVF), hemoglobin, high-sensitivity C-reactive protein (hs-CRP), glucose, hemoglobin (Hb) A1C, insulin, total cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol, alanine aminotransferase (ALT), retinol (vitamin A), 25-hydroxyvitamin D, Tocopherol (vitamin E), thyroid stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3). All blood samples were analyzed at Karolinska University Laboratory, Sweden.Occasionally missing data of biomarkers occurred due to that blood samples were compromised at the laboratory, preanalytical factors such as hemolysis, or blood sample volume was not enough to be analyzed. Also, two high values of CRP, due to confirmed recent infection (Covid-19 and sinusitis) of 25 and 30 mg/L, were excluded from statistical analyses.