Conclusion
HTN
ELEVATED BLOOD PRESSURE, HYPERTENSION, HTN
In this study, we demonstrated the pattern of plasma metabolite concentrations in individuals with different blood pressures, including normal blood pressure, elevated blood pressure, stage 1 and stage 2 hypertension, and identified 5 metabolites as potential biomarkers for predicting stage 2 HTN. Our results suggest that high plasma levels of carnitines and various acylcarnitines as well as low plasma levels of glycine may play a crucial role in the development and progression of HTN.