Gastrointestinal disorders in PD patients were improved by FMT
gastrointestinal symptoms, tremor, rigidity, PD, nonmotor dysfunction, gait impairment
GASTROINTESTINAL DISORDERS
Apart from PD symptoms, such as bradykinesia, rigidity, resting tremor, and gait impairment, patients with PD often suffer from nonmotor dysfunction, especially gastrointestinal disorders. As a microbiota-modulating therapy, FMT is safe and effective for restoring gut microbiota and treating gastrointestinal symptoms. We performed IBS-SSS, GSRS, and IBS-QoL scales for assessing whether participants benefited from interventions regarding gastrointestinal disorders. Both arms showed improvement in gastrointestinal symptoms.As In addition, according to Bristol evaluation, stool characteristics of participants in the placebo arm improved significantly at week 4 (time effect, B = 1.21 [0.37, 2.04], 