4.4. Exclusion Criteria
mental illness, hyponatremia, dementia, emphysema, ARDS, hyperkalemia, Porphyria, trauma
CHRONIC RENAL FAILURE, PORPHYRIA, ADRENAL CRISIS, HYPONATREMIA, CHRONIC BRONCHITIS, HYPERSENSITIVITY, EMPHYSEMA, OTHER VIRAL INFECTION, ANURIA, INTERSTITIAL LUNG DISEASE, ARDS
Patients with a history of chronic bronchitis, emphysema, interstitial lung disease, or any other preexisting lung conditions.Individuals with contraindications for the use of spironolactone.Hypersensitivity to spironolactone or any of its components.Pregnant individuals (with mandatory pregnancy testing for those of reproductive age) or breastfeeding mothers.Patients with mental illness or dementia who are unable to provide informed consent for participation in the study.ARDS resulting from another viral infection (testing negative for SARS-CoV-2).ARDS caused by other factors or trauma.Presence of ionic imbalances, such as hyperkalemia or hyponatremia.Adrenal crisis.Acute or chronic renal failure, with a creatinine clearance rate below 30 mL/min.Anuria.Porphyria.Chronic use of mineralocorticoid receptor antagonist (MRA) medications from the spironolactone group.