Statistical analysis
The normal distribution of quantitative data was assessed by the Shapiro-Wilks test and Q-Q plot. To describe data, we used, mean and standard deviation, median and range, frequency and percentage. To compare the baseline variables between the two groups we used an independent t-test, Mann-Whitney test, chi-square test, and Fisher exact test. Evaluation of the variables’ changes in different follow-ups was performed using a linear mixed model. To compare the groups in different follow-ups we used Multivariate Analysis of Variance (MANOVA). All statistical analysis was performed using SPSS software Version 25 (IBM Corp. Armonk, NY). All tests were two-sided and P-value less than 0.05 was considered statistically significant.