2.9.2. Planned data analysis.
SECONDARY
Intention-to-treat (ITT) analysis will be used for baseline comparisons and the assessment of the effect of EZTG on the total number of retrieved oocytes per COS cycle, as well as other secondary outcomes. T-test, Wilcoxon rank-sum test, or chi-square test will be used to test for differences. The results will be given as mean (standard deviation), median (interquartile range), or frequency (percentage) according to the type and distribution of the variables. A 2-sided In addition, a subgroup analysis will be performed according to AFC strata (<5 or ≥5) using a similar approach to the primary analysis. Multiple imputations will be used to process missing values in the data of this study. All statistical work will be performed on SPSS version 26.0 software (IBM Corporation, Armonk, NY).