Limitations
CRITICALLY ILL
This study has several limitations. The amount of aerosolization that occurs in patients in clinical practice is highly variable and dependent upon many factors, making it impossible to exactly replicate aerosolization. Creating a model that was standardized (ie, particle type, airflow, ventilation pressure) and capable of generating substantial contamination allowed comparisons across a variety of different clinical contexts. The scenarios were limited to the performance of the airway procedure, so study results do not consider other aspects of patient care required for patients who are critically ill. Also, blinding video reviewers to the intervention was not possible, so this may have introduced potential bias, which was mitigated by conducting reviewer training and blinding to participant identity.