2.2.12. Statistical Analysis
In the clinical study, the cumulative days of each symptom during the intake period was calculated on the basis of the physical health questionnaire survey and analyzed using the chi-square test for the primary outcome.On the basis of the measured values, averages and SD values were calculated for each immunological marker. The normal distribution of each data point was evaluated using the Shapiro–Wilk test. For variables showing a normal distribution, between-group comparisons were performed using an unpaired In the fecal microbiota analysis, between-group comparisons were performed using the Wilcoxon rank-sum test, and within-group comparisons between 0 and 12 weeks were performed using the Wilcoxon signed-rank test.Statistical analyses were performed using the IBM SPSS Statistics version 27. A 