Recruitment and retention
RECRUITMENT
Successful recruitment to clinical trials requires engagement of participants representative of the wider target population, in numbers sufficient to meet the requirements of trial-specific power calculations, in efficient time-frames [Sub-optimal recruitment and retention can affect the ability to draw valid conclusions from trial data, and increasing the probability of Type II error [The current study is the first to prospectively explore the characteristics of a group of people with MND, in parallel with the launch of a national trial, and follow up on their involvement after a one year time frame. In these findings we report the demographics, clinical features and attitudes to research of a subgroup of people with MND who were in the process of decision-making, related to an actively recruiting trial, and the outcome of this decision.