Author contributions
RECRUITMENT
N.D. was responsible for the concept of the study. J.P., N.G., M.T., and N.D. designed the trial and study protocol. J.P. was responsible for the site work including the recruitment, study visits and data collection. S.T. facilitated recruitment. S.T. and M.C.M. provided relevant medical advice and information. M.T. performed the viral load analysis. J.P., N.G., M.T., S.T., A.P., and N.D. contributed to the data interpretation. A.P. did the main statistical analysis. J.P., N.G., A.P., M.T., S.T., and N.D. prepared the manuscript. All authors reviewed and accepted the paper before submission.