Strengths and Limitations
The strengths of our study are as follows: (1) a cluster randomized controlled intervention design with a 1-year follow-up and (2) the addition of evidence on behavioral bout accumulation, which was limited to measures of central tendency for sedentary behavior bouts when using sit-to-stand desks. Our study expands the evidence base by adding a description of how sedentary, standing, and stepping bouts are accumulated across categorized bins of bout duration. This is also the first study to report the impact of treadmill desks and a head-to-head comparison of sit-to-stand and treadmill desks on behavior accumulation patterns.Missing data are unlikely to have biased the results, given that data were determined to be missing at random and appropriately handled, but losses to follow-up may limit the generalizability of these findings because attrition rates (