Outcomes
breast cancer
RECURRENCES, SECONDARY, BREAST CANCER
The primary outcome of the BREAST-MRI trial was local relapse-free survival (LRFS). All the locoregional recurrences were confirmed by biopsy. The secondary outcomes were overall survival (OS), the proportion of patients whose surgical approach was modified to mastectomy, and the reoperation rate.The LRFS was defined as the length of time after primary treatment for breast cancer that the patient survives without any locoregional signs or symptoms. All the locoregional recurrences were confirmed by biopsy. The OS has considered the length of time after primary treatment for breast cancer that the patient was still alive. The proportion of patients whose surgical approach was modified to mastectomy was the percentage of patients who have changed the surgical management due to MRI findings before surgery. The reoperation rate is the percentage of new surgeries to achieve clear margins until 6 months from the first surgery.