Institutional Review Board Statement
This study was conducted under the principles of the Declaration of Helsinki, with the approval of the ethics review board of the Ethical Committee of Nihonbashi Cardiology Clinic (NJI-021-10-01), and according to the ethical guidelines for human research (Ministry of Education, Culture, Sports, Science and Technology; Ministry of Health, Labor and Welfare; Ministry of Economy, Trade and Industry Japan). The trials were registered in the UMIN Clinical Trials Registry (UMIN000046306).