Statistical analysis
EVENTS
General aspects of data quality were presented descriptively. This included source specific data distribution and overlap, completeness (percentage of EHR data transferred to the NDR), uniqueness (percentage of NDR data that could be linked to EHR data), duplicate and extraneous NDR data, reporting rate (number of unique NDR entries per patient year) and timeliness between corresponding NDR (date of entry or examination utilized as applicable) and EHR entries.Validation was carried out for corresponding entries in the NDR and EHRs as well as for microvascular events based on NDR versus EHR data. EHR data were considered the golden standard. For the continuous variable creatinine, the exact percentual agreement in the NDR versus EHRs and the single measure type ICC, using a two-way mixed model with an absolute agreement definition