Statistics
REGRESSION, BLOOD, DELHI
A blinded database was created in MS-EXCEL by the Delhi team. Two UK investigators assessed the data independently. Data was analysed with GraphPad Prism version 9. Following completion of data processing, the trial was un-blinded. To assess time to WHO OS ≤ 3, daily WHO OS were analysed by simple linear regression and two-way ANOVA (withdrawn patients who failed to reach WHO OS ≤ 3 were excluded from the analysis). Blood biomarkers were analysed via two-way ANOVA. Chi-square tests were applied to assess the difference between proportions for categorical variables, and the two-way ANOVA, Student’s t-test, and/or simple linear regression were used for assessing significance in the difference of means for continuous variables, as appropriate. The Mann–Whitney test was used where measurements followed non-Gaussian spread. A 