Introduction
death, breast cancer
SIDE EFFECTS, RECURRENCE, BREAST CANCER
Adjuvant tamoxifen treatment reduces recurrence and death from oestrogen receptor (ER)-positive breast cancer in pre- and postmenopausal women [Tamoxifen is a selective ER modulator that acts as an oestrogen antagonist in the breast, along with oestrogen-like agonistic effects on the endometrium, skeleton, coagulation system, and metabolism of lipids [Most studies on tamoxifen side effects have been restricted to breast cancer patients making it difficult to disentangle tamoxifen-specific side effects [Side effects not only affect adherence to adjuvant tamoxifen treatment [We recently published the first results of the KARISMA trial [