Introduction
hernia, IH
Loop-ileostomy closure leads to incisional hernia (IH) in one fifth to one third of patients [The synthetic mesh does not increase the surgical site occurrence rate compared to biological mesh in large randomized controlled trial (RCT) including clean and clean contamined ventral hernia repair [Biological meshes have been considered safer than synthetic ones for use in contaminated surgical sites. However, clinical evidence does not support the practice [The objective of the Preloop trial is to compare the safety and efficacy of SM (Parietene Macro™, Medtronic, Minneapolis, MN, USA) and BM (Permacol™, Medtronic, Minneapolis, MN, USA) in a non-inferiority setting after temporary loop ileostomy closure during both short- and long-term follow-up. In this paper, we report the 30-day SSIs as primary outcomes of the study. The IH rate will be reported after the study patients reach the 12-month follow-up.