Author contributions
RECRUITMENT
R.S., B.A., X.W., Z.N., V.M., and I.B. contributed to the study design. V.M., M.V., J.M.S., V.G., T.H.-G., B.D., O.S., C.C.-S., J.-M.M., A.I., M.M., C.C., A.P., and I.B. contributed to patient recruitment. B.H. contributed to PK data analysis and interpretation. I.A. and E.F. contributed to 