2.1. Study Design
This experimental study was performed in the College of Dentistry, Prince Sattam bin Abdulaziz University (PSAU), Al Kharj, and the College of Dentistry, King Saud Bin Abdulaziz University (KSAU), Riyadh, after obtaining ethical approval from the Institutional Review Board, PSAU, IRB No (PSAU2021011), and the College of Dentistry Research Center, KSAU, CDRC No (FR0626).