2.4. Data Collection
ONCOLOGY
As per protocol, blood samples of the patients were collected at randomization, at 3 months from completion of the radiant treatment, and at the eventual clinical relapse. All the samples were stored in the European Institute of Oncology (IEO, Milan, Italy) Biobank.Hematological parameters, including neutrophils, lymphocytes, platelets, hemoglobin, cholesterol, albumin, glycemia, lactate dehydrogenase (LDH), and body mass index (BMI) were collected at baseline. Moreover, common serum-derived biomarkers collected at different time points were considered as standalone biomarkers and together for the calculation of different nutritional and inflammatory indexes. In particular, nutritional status was evaluated through the following indexes:Controlling nutritional status (CONUT) score [PNI [NRI [NLR [NLR–albumin ratio (NLRAR) [HALP score [PLR score [