Number of responders (≥PR) and non-responders (<PR) in the BELLINI trial as assessed by IRC and the dR algorithm using 50% of all laboratory measurements.
dR, derived response; IRC, independent review committee; PR, partial response.Differences in overall response rate between the intervention and placebo arms in the trial based on IRC assessment could still be replicated by the algorithm after excluding 50% of all laboratory measurements (overall response rate in intervention vs. placebo arms by IRC: 82% [159/194] vs. 68% [66/97], OR 2.10; by dR: 80% [156/194] vs. 69% [67/97], OR 1.80; 