Patient Characteristics and Disposition
tumor, tumors
TUMOR, TUMORS, APPENDICEAL CANCER
Between December 2013 and January 2021, a total of 24 patients were enrolled in the study, with median (range) age of 63 (38-82) years and an equal proportion of men and women (eg, 12 men [50%]); all patients had ECOG performance status of 0 or 1. Eleven patients were randomized to chemotherapy first, and 13 patients were randomized to observation first. Most patients (20 patients [83%]) had well-differentiated tumors, and 4 patients (17%) had well-to-moderately differentiated tumors. Pathological diagnosis was confirmed by a pathologist with specific expertise in appendiceal cancer, and graded using a 3-tiered system evaluating tumor cellularity, destructive invasion, presence of signet ring cells, as well as complexity of tumor architecture