Reading of images
edema
EDEMA
At the final reading session (week 104), all baseline and post-baseline images were scored by 2 central independent and experienced readers who were blinded to treatment assignment and image sequence. The cases with the highest between-reader differences for change in score from baseline were identified for adjudication review by a third independent reader. Adjudication review was triggered independently for the spine and SI joint and each imaging modality. The top 5% of radiograph reads with the highest difference in change of scores, the top 5% of discrepant cases of total SI joint edema score, and the top 10% of discrepant cases of total spine edema scores were scored independently by a third reader. All data are reported from the final reading session (all time points up to week 104), which was independent from previous reading sessions (performed for eligibility assessment or for primary results analysis) [