Secondary and Descriptive Outcome Measures (Modified Intention-to-Treat Population)
depression, Depression, PTSD, Anger
Abbreviations: CAPS, Clinician-Administered PTSD Scale; BDI, Beck Depression Inventory; PCL, PTSD Checklist; PSQI, Pittsburgh Sleep Quality Inventory; STAXI, State-Trait Anger Expression Inventory.SI conversion factors: To convert cortisol to nanomoles per liter, multiply by 27.588; ACTH to picomoles per liter, multiply by 0.22.The CAPS total score (past week symptoms) has a possible range of 0 to 136, with higher scores indicating worse PTSD symptoms overall. The CAPS intrusive symptom subscale scores range from 0 to 40, the CAPS avoidance symptom total scores range from 0 to 56, and the CAPS hyperarousal symptom total scores range from 0 to 40, with higher scores indicating worse PTSD symptoms in the corresponding functional domains. Total BDI scores range from 0 to 63, with higher scores indicating more severe depression symptoms. Totals from the PCL range from 17 to 85, with higher scores indicative of more severe PTSD. The PSQI total scores range from 0 to 21, with higher scores indicating worse sleep quality. Negative values for changes over time for the within-group and between-group comparisons indicate improvement in functioning or quality of life. The score ranges are not based on the collected sample; instead, they are based on the standard questionnaire in general.For the descriptive neuroendocrine outcomes, data are for the change from baseline to 1 week.For the descriptive neuroendocrine outcomes, data are for the change from baseline to 4 weeks.