ETHICAL ASPECTS AND STUDY DESIGN
This was a prospective randomized clinical trial that was approved by the Ethics
Committee on Human Research of University of São Paulo, School of Dentistry,
under the protocol number: 3.311.813. This study was also registered in the
REBEC clinical trials (RBR-48g9q6). The Consolidated Standards of Reporting
Trials (CONSORT) statement and guidelines were followed.