Whole-brain regressions of clinical scores with sgACC connectivity reveal correlations between sgACC-dACC rsFC and anhedonia scores
REGRESSION, REGRESSIONS
Post-hoc correlation of significant clusters with symptom improvements has associated bias (as described in “Methods” section (Data Analysis)); a regression analysis at the whole-brain level has reduced power but is unbiased. We carried out whole-brain regressions of SHAPS/MADRS scores with sgACC rsFC maps, firstly exploring whether any regions showed significantly different relationships with clinical scores following ketamine 