Ethical review
This human study was approved by the Ethics Committee of the Research Institute of Surgery (2021–179) and was registered by the Chinese Clinical Trial Registry (Date: 09/12/2021, ChiCTR2200055772). All the participants provided written informed consent before inclusion in this study. All experimental procedures were approved by the Animal Ethics Committee of Army Medical University, China, and were performed in accordance with the National Institutes of Health “Guidelines for the Care and Use of Laboratory Animals”. The study was carried out in compliance with the ARRIVE guidelines. All methods are reported in accordance with ARRIVE guidelines (