Primary Outcome (Persistent Organ Dysfunction–Free Days in 30 Days) by Subgroups
CKD, chronic kidney disease, cardiac disorders
ADVERSE EVENTS, ADVERSE EVENT, CARDIAC DISORDERS
CKD indicates chronic kidney disease; EuroSCORE, European System for Cardiac Operative Risk Evaluation.The observed 30-day mortality rate was 4.2% (n = 29) in the selenium and 5.0% (n = 35) in the placebo group (odds ratio, 0.82; 95% CI, 0.50-1.36; The overall median (IQR) time to discharge alive from the ICU and hospital was 2.2 (1.1-5.1) days and 8.9 (6.2-14.9) days, respectively, with no statistically significant difference between groups for either measure (In total, 57 patients (8.2%) and 60 patients (8.6%) in the selenium and placebo groups had at least 1 serious adverse event, respectively. The most common class of serious adverse events was cardiac disorders occurring in 29 patients (4.2%) and 30 patients (4.3%) in the selenium and placebo groups, respectively (eTable 6 in 