Rationale of the randomization method.
The intervention arm will have access to the CINDERELLA platform which entails the information related to surgery and/or radiotherapy. Upon patient’s request, the platform will provide the patient with a matched picture as an example of her own aesthetic outcome according to the surgical procedure she chooses, and an objective evaluation of this aesthetic outcome (e.g., good/fair). The trial will not interfere with the type of locoregional therapy offered to the patient, or any treatment, but will evaluate the CINDERELLA approach and standard approach in terms of achieving an optimized shared decision making.In total, considering both primary objectives (i) to evaluate the differences between the arms in patient’s agreement of expectations and aesthetic outcome and (ii) in the experimental arm only, the agreement of the AI-evaluation and patient’s post-therapy self-evaluation, it is estimated that a minimum of 515 patients will be enrolled in each arm of the study, based on recent information (frequency and dropout) from the clinical centres. The trial objectives are summarized in 