Competing interests
The current study was funded by Janssen Research and Development. KR MD, Dr GJ and Prof Dr JvG declare no competing interests. Dr PdB, Dr PvdA, Dr HB, Dr MC, Dr AB, Dr LvN and Prof Dr WD are employees of Janssen and own Johnson and Johnson equity. Dr MB is employed by the University of Oxford and has acted as a consultant for Jansen Research and CHDR.