Background
pelvic pain, blood loss, uterine fibroids, anemia, infertility, uterine leiomyomas, fibroids
POSTPARTUM HEMORRHAGE, CONTRACTIONS, BLOOD LOSS, VASCULAR TUMORS, UTERINE FIBROIDS, ANEMIA, UTERINE LEIOMYOMA, FIBROIDS, COMPLICATIONS
With about 235 million women affected globally [Clinically, uterine fibroids are frequently asymptomatic, but in 30% of cases, fibroids can be symptomatic and cause various critical complications. These complications include pelvic pain, heavy menstruation, anemia, frequent urination, bowel problems, and infertility [The current management options for fibroids include surgical, radiological, and pharmaceutical management [Regardless of the myomectomy approach, uterine leiomyomas are highly vascular tumors [Few trials have looked at the effectiveness of various perioperative pharmacologic treatments, such as oxytocin, tranexamic acid (TA), and ethamsylate, to reduce blood loss and associated morbidities during myomectomy [Oxytocin is one of the hormones that the pituitary gland is their primary source of secretion, as its primary role is to cause uterine contractions during childbirth. For preventing postpartum hemorrhage, oxytocin is the drug of preference [TA is a manufactured version of the human amino acid lysine. Its mechanism of action is reducing through its antifibrinolytic action as it inhibits plasminogen from being transformed into plasmin [