Post hoc analyses
HED, weight loss
SECONDARY
As a post hoc outcome, the need for medication, after completion of follow-up testing, was calculated based on the prespecified algorithm. Reductions of glucose-lowering medication were 11%, 92%, 81% and 89% in CON, DCON, MED and HED, respectively (Table The role of weight loss on the primary and secondary outcomes was explored in a post hoc statistical mediation analysis (Supplementary Table 