Conclusions
obese, overweight, CKD, weight loss
OBESE
Our study suggests that TRF may help improve renal function in overweight and obese moderate-to-severe CKD patients. This may be due to the patients’ weight loss, stable nutritional status, and the increase in beneficial bacteria in the gut microbiota. It may also have been due to the decrease in uric acid and serum phosphorus levels. Patients maintained good compliance and clinical implementation reliability under strict monitoring by health care professionals. The results suggest that TRF may be a safe and effective dietary intervention for overweight and obese CKD patients. However, long-term, large-scale randomized clinical trials are needed for further validation.