Intervention
vitiligo, vitiliginous lesions
VITILIGO
Three vitiliginous lesions in each patient were randomized to lesions A, B or C to receive bimatoprost 0.01% monotherapy, combination therapy consisting of bimatoprost 0.01%, and NB-UVB phototherapy, and normal saline solution placebo. The bottles containing the study solutions (placebo and bimatoprost 0.01%) were all the same color and shape, and each was labeled A, B, or C to correspond with lesions A, B, and C. The lesion randomization pattern was illustrated and recorded in a case record form, and detailed written instructions were provided for each participant. All 3 study solutions (A, B, C) were applied twice daily to each respective lesion. NB-UVB was administered using a DuaLight targeted phototherapy system (Theralight LLC, Lindon, UT, USA) to the vitiligo lesion randomized to the combination therapy group. Phototherapy was performed twice weekly. The intensity of phototherapy was started at 200 mJ/cm