Introduction
lung cancer, lung cancer death
LUNG CANCER, LUNG
The landmark National Lung Screening Trial demonstrated that annual low-dose computerized tomography (LDCT) for lung cancer screening (LCS) reduces lung cancer death by 20%.Clinical trials have established the efficacy of behavioral treatment, medication treatment, and combination behavioral and medication treatment for long-term smoking cessation.Incorporating chronic care modelTLC delivered for 1 year was previously demonstrated to be efficacious in a confirmatory, randomized clinical trial.PLUTO used a 2-stage, sequential, multiple assignment, randomized trial (SMART) design.