Other metabolites’ profiling
We also explored the changes in other microbial-derived metabolites over time in the participants (untargeted metabolomics analysis). While we did not find any metabolites to be significantly different in control participants over time, we found 46 metabolites to be significantly different in meditators overtime points. Most of these metabolites decreased in T2 and subsequently increased at T3 (Fig. Metabolomics intensity in log2 units. Heatmap of metabolites that have significantly changed across two timepoints. Most metabolites that show significant change are decreased in T2