Future directions of the study
hypothyroid, fatigue
HYPOTHYROID, HYPOTHYROIDISM
It could be suggested that future studies with bigger sample sizes, longer durations, and different types and doses of probiotics and prebiotics further assess this effect in hypothyroid patients. The effect of synbiotics and probiotics with various content of pro- and prebiotics could be assessed on other important aspects of hypothyroidism, such as fatigue, cardiovascular status, etc. Assessment of the microbiota and its metabolites could also clarify the mechanism through which synbiotics affect these patients’ health.