1. Introduction
muscle mass, RET, inflammation, sarcopenia, physical disability, cardiometabolic disorders, TG
INFLAMMATION, OXIDATIVE STRESS, SARCOPENIA, PHYSICAL DISABILITY
Menopause is a condition associated with an increased risk of dysregulation in cardiovascular and metabolic health among older women. While fish oil (FO) has garnered great attention for its health-enhancing properties, its potential for enhancing cardiometabolic health in this demographic remains to be established. The purpose of this study was to determine the clinical efficacy of an 8 wk administration of FO combined with programmed resistance exercise training (RET) on physical function and risk factors associated with cardiometabolic health in healthy older women. Twenty, healthy, older women were randomly assigned to one of the two experimental groups: resistance training with placebo (RET-PL) or RET with fish oil (RET-FO). Physical function, blood pressure (BP), triglyceride (TG), and systemic inflammation and oxidative stress biomarkers were assessed before and after the intervention. Statistical significance was set at With age, humans inevitably experience changes in cardiometabolic health and a decline in muscle mass (i.e., sarcopenia), which may contribute to an increased incidence of physical disability [Key features of aging encompass elevated levels of reactive oxygen species (ROS) and chronic low-grade inflammation, which are potential pathophysiologic factors associated with cardiometabolic disorders and the accelerated sarcopenic process [Resistance exercise training (RET) is acknowledged as the most cost-effective counteractive strategy for enhancing muscle mass, improving physical function, and reducing morbidity in older adults [Omega-3 polyunsaturated fatty acids (