5. Conclusions
Complete revascularization with the routine use of the virtual planning tool in one-stage iFR-guided PCI is a feasible practical strategy in an everyday Cath lab environment following the protocol designed for the study. One-stage iFR-guided PCI requires fewer PCI attempts until complete revascularization than does angiography-guided staged PCI. No statistically significant safety signals were documented in the number of PCI related MACE both during acute hospitalization and at 3-months follow-up. Further studies will help assess the role of routine iFR co-registration guidance in one-stage complete revascularization PCI to treat patients with MV ACS. After the lack of safety signals in the pilot study, further trial progress commenced to gain statistical power.