The effect of MDA regimens on growth and nutritional status
stunting or wasting, wasting, MUAC-Z, stunting
REGRESSION, WASTED, WASTING
We will tabulate the descriptive summaries (mean, SD, min, max) on LAZ, WAZ, WHZ, and MUAC-Z score for each treatment arm. We will analyze the impact of AZI MDA on growth and nutritional status using mixed-effects regression model with identity link and random intercepts for clusters and for children.In addition, we will perform analyses on dichotomous outcome variables, including moderate-to-severe and severe stunting (LAZ <  − 2/LAZ <  − 3), moderate-to-severe and severe underweight (WAZ <  − 2/WAZ <  − 3), and moderate-to-severe and severe wasting (WLZ <  − 2/WLZ <  − 3). We will tabulate the proportions of stunted, underweight, and wasted per treatment arm and age group (6–8 months, 12–14 months, respectively) and calculate their differences (95% CI). We will test a hypothesis that there is no difference between the treatment arms with respect to the prevalence of stunting or wasting by using a mixed-effects logistic regression model with random intercepts for clusters and for children. The marginal risk ratios will be predicted from the obtained model coefficients.