NIR Tracer
SGM-101 was manufactured in accordance with Good Laboratory Practice guidelines and supplied by Surgimab. The SGM-101 active ingredient is a covalent conjugate of the SGM-Ch511 anti-CEACAM5 chimeric monoclonal antibody with the fluorochrome BM-104. Patients in this study were administered 10 mg of SGM-101 intravenously for 30 minutes followed by a 50-mL flush of isotonic saline to account for the dead volume of the tubing. Patients were administered SGM-101 3 to 5 days (±1 day) before surgery at the Center for Health and Precision Surgery and monitored for a minimum of 1-hour after infusion.