Limitations
vitiligo
VITILIGO
This study has some mentionable limitations. First, our data were collected from a single center. Moreover, our center is a large, university-based, national tertiary referral center that is routinely referred complex cases that are thought not to be sufficiently treatable at other levels of care. As such, some aspect of this study may not be immediately generalizable to vitiligo found in other care settings. Second, although we enrolled a number of subjects that satisfied the minimum number established by our sample size calculation, six of those patients were excluded due to inconvenience to remain in the study or deviation from the study protocol. Since our study analyzed less than the calculated minimum number of subjects, our study has lacked the statistical power needed to identify all statistically significant differences and associations between and among the three study interventions.