Funding
This study was supported by the National Natural Science Foundation of China (82270731, 82000703); the Jiangsu Provincial Natural Science Foundation (BK20211054); a project of Qing Lan of Jiangsu Province; a project of Jiangsu Provincial Post Graduate Innovation Plan (KYCX21_2701, KYCX22_2903); Science and technology development fund of Affiliated Hospital of Xuzhou Medical University (XYFC2020001; XYFY2020038); Xuzhou key R & D Program (Social Development) (KC20160); Xuzhou Medical leading Talent training Project (XWRCHT20210038); Beanstalk talent of Affiliated Hospital of Xuzhou Medical University; and a project of Practice and Innovation Plan of Jiangsu Province (SJCX21_1147).