Experimental design and data collection
head TD-fNIRS
Participants were fifteen healthy individuals who met eligibility criteria and consented to participation in the study (8 females and 7 males, 24–48 years old; “Overview of study design and usage of whole head TD-fNIRS neuroimaging in a clinical environment. (During each dosing visit, participants completed two experimental runs: a baseline run including a short breathing challenge (~ 14 min), followed by a bolus intramuscular injection to the deltoid of either saline or ketamine (during which participants were partially reclined on a couch for 30 min post-dose (Fig. 