Discussion
colorectal cancer, postoperative cognitive impairment, cognitive impairment, cancer, Alzheimer’s disease, cognitive decline, cognitive deterioration, Cognitive impairment
CANCER, COLORECTAL CANCER, DISORDERS
A considerable fraction of cancer patients undergo cognitive deterioration and functional decline, particularly among individuals aged 85 and above (Cognitive impairment and its correlation with colorectal cancer have garnered increasing interest in recent years, with patients exhibiting a higher prevalence of cognitive impairment compared to the general population (To construct a clinical prediction model for CRCI outcomes, we analyzed the clinical information of patients, incorporating variables such as age, exercise intensity, BMI, comorbidities, CRA, and mobility. Alzheimer’s disease and cancer frequently coexist in the elderly population, with CRCI showing a significant correlation with age. The likelihood of cognitive impairment increases with age (The discernment of these risk factors and potential biomarkers bears clinical ramifications for the prognostication and management of postoperative cognitive impairment in patients undergoing ileostomy for colorectal cancer. Early detection methods and intervention for cognitive decline may contribute to delaying the onset and progression of neurovascular disorders such as Alzheimer’s disease (