Inclusion and exclusion criteria
pulmonary embolism, tibial fracture, abnormal liver, kidney, or coagulation function, fracture, allergy, fractures
ALLERGY, PATHOLOGICAL FRACTURE, DEEP VEIN THROMBOSIS (DVT), PULMONARY EMBOLISM
Patients aged > 18 years with a diagnosis of unilateral tibial fracture were included. Patients aged < 18 years with open fracture; pathological fracture or old tibial fracture; allergy to TXA; preoperative blood transfusion; history of pulmonary embolism (PE) or deep vein thrombosis (DVT); abnormal liver, kidney, or coagulation function; and incomplete follow-up data were excluded. In this study, two doctors classified fractures in accordance with the AO/OTA classification. The patients were randomly divided into two groups with the help of a computer-generated table (