Study design and subjects
psychiatric
SARS-COV-2 INFECTION, COVID-19 INFECTION, CARDIOPULMONARY, CHRONIC RESPIRATORY INSUFFICIENCY, PATHOLOGY
This was a prospective single-center observational cohort study. All patients who were admitted between April to June 2020 to any of the intensive care units (ICU) of the University Hospital of Besançon (France) for a COVID-19 infection were contacted upon hospital discharge and invited to participate in the trial. The study consisted of a follow-up at 3, 6 and 12 months after symptom onset (NCT04519320, 19/08/2020). Cardiopulmonary exercise capacities were only assessed at the 12 months follow-up. Patients were eligible if they were > 18 and < 80 years old and had initially confirmed SARS-CoV-2 infection by quantitative RT-PCR on nasal swabs or bronchoalveolar lavage. Patients were excluded if they were known to have prior chronic respiratory insufficiency, if they had a significant psychiatric pathology, or if they had a life expectancy estimated at less than one year. The protocol was approved by the ethics committee (Comité de Protection des Personnes (CPP) Grand‐Est N° ID RCB: 2020-A01067-32, 21/04/2020) and written informed consent was obtained from all patients at the time of enrollment.