Results
ischemia
ISCHEMIA
A total of 34 patients were included in the study. Baseline characteristics of the cohort are presented in Table 
Baseline characteristics of the cohort. IQR – interquartile range, hs-cTnI – high sensitivity cardiac troponin I, LDL – Low Density Lipoprotein, HDL – High Density Lipoprotein, TCA cycle - Tricarboxylic Acid CycleTable 
Results from 2-way ANOVA of each metabolite between the 30 s, 60 s, 90 s ischemia and control groups. Selected here are all metabolites that had a significant time and group difference. LDL – Low Density Lipoprotein, HDL – High Density Lipoprotein, VLDL – Very Low Density Lipoprotein, IDL - Intermediate Density Lipoprotein
Difference between the 90 s ischemia group and control for the main lipoprotein components. Blue 90 s ischemia, yellow – control
Difference between the 90 s ischemia group and control for selected metabolites of the Tricarboxylic Acid Cycle. Blue 90 s ischemia, yellow – controlThe PCA score plots of the concentration changes 15 and 60 min after the control treatment and 90 s ischemia are shown in Fig. 
Principal component analysis of changes in metabolite concentrations and lipoprotein parameters the 90 s ischemia group and control after 15 min (A) and 60 min (B), and metabolite concentrations and lipoprotein parameters that change along PC1 (C) and PC2 (D) after 15 min. All concentration changes are displayed as percentage changefrom baseline – Control samples are shown in yellow and 90 s ischemic samples in blue,. The percentages displayed in panel A and B denote the variation explained by the principal components. LDL – Low Density Lipoprotein, HDL – High Density Lipoprotein