Patients
breast lesions
The study was approved by the institutional review board, and written informed consent was obtained. From April 2015 to June 2017, patients at our center who had suspicious breast lesions were prospectively included in the study and randomly assigned to undergo either high-temporal-resolution (27 phases) or conventional low-temporal-resolution (7 phases) DCE-MRI. MRI was performed in the second week of the menstrual cycle in premenopausal patients. The inclusion criteria included the following: (1) breast lesions were found through either physical examination or imaging, such as mammography or ultrasound; (2) no surgery, biopsy or medication for treating breast lesions was conducted or administered before the DCE-MRI scan; and (3) all patients were ≥ 18 years old. The exclusion criteria were as follows: (1) loss to follow-up or lack of pathological results; (2) breast lesions less than 5 mm; (3) any prior treatment of the lesions; and (4) poor image quality. Finally, a total of 140 patients met the above criteria, of which 56 patients had BI-RADS 4 in this study. The flowchart of patient selection is shown in Fig. The flowchart of patient selection