2.5.1. Endpoints for Inference Statistics
Cognitive development was assessed at 6, 12, and 24 months by trained assessors using the Bayley Scales of Infant and Toddler Development, third edition (Bayley-III) [Social-emotional development was assessed at 3, 6, 12, 18, and 24 months using the Ages & Stages Questionnaires: Social-Emotional, second edition (ASQ:SE-2). The ASQ:SE-2 is a validated parent-rated questionnaire measuring social and emotional development in young children based on 7 subscales: self-regulation, compliance, social communication, adaptive functioning, autonomy, affect, and interaction with people. The reported validity is 84%, and the test-retest reliability is 89% (Infant and child sleep was assessed at 3, 6, 12, 18, and 24 months of life using the BISQ [Infant behavior was assessed at 3, 6, and 12 months using the Infant Behavior Questionnaire–revised (IBQ-R) short form [At 18 and 24 months, toddler behavior was assessed using the Toddler Behavior Assessment Questionnaire (TBAQ) [Two tablet-based, self-constructed performance tasks were administered at 18 and 24 months to assess early learning parameters: (1) Early learning was explored using an object reversal learning task for infants (ORTi), an age-adapted task based on the principles of the probabilistic object reversal task (pORT) [