Physical activity
The training program included two training sessions per day (i.e., from Monday to Friday) for a period of 3 weeks under medical supervision. Volunteers walked on a treadmill. Each participant monitored his intensity with a heart rate (HR) chest strap (Polar H10, Polar Electro Oy, Finland). All subjects completed 28 ± 2 sessions of physical training.The COMB group completed a combination of high-volume, low-intensity exercise (~ 80% of overall training volume) and low-volume, high-intensity exercise (~ 20%). Each session consisted of a 5-min warm-up (50% of V′OSchematic representation of training protocols: combined training (COMB, panel In addition, volunteers had 1 h day