Tolerance test
airway obstruction, SD
AIRWAY OBSTRUCTION
The tolerance test was performed in 57 patients, whereof 2 (3.5%) patients did not receive salbutamol dose aerosol in advance. All patients passed the tolerance test without severe airway obstruction (defined as a decrease in FEVTolerance test.
Abbreviations: FEV1, forced expiratory volume in one second; FVC, forced vital capacity; SD, standard deviation.A total of 16 patients (28%) were known to have FEV1% of predicted <50% before the use of the inhaled study medication, of which 11 patients (68.8%) were treated with TIS. For this subpopulation with a FEV1 <50% of predicted, a significant improvement was found in the FEV1% of predicted from 39.1% (SD 7.4) to 41.5% (SD 8.9) during the tolerance test (