Study population
stress incontinence, incontinence, urinary incontinenceExclusion, urinary retention
STRESS INCONTINENCE, OVERACTIVE BLADDER, MULTIPLE SCLEROSIS, INCONTINENCE
Key inclusion and exclusion criteria are presented in Table Enrollment criteria of the COMPOSUR studyOAB, overactive bladder; PRO, patient-reported outcome; PTNS, percutaneous tibial nerve stimulation; SNM, sacral neuromodulation; UUI, urge urinary incontinenceExclusion criteria include any history of OAB treatment with botulinum toxin A, sacral neuromodulation, percutaneous tibial nerve stimulation, external beam radiation therapy, or urinary stents within the last 6 months; pelvic or lower urinary tract surgery within the last 6 months; or urethral catheterizations within the last 3 months. Additional exclusion criteria are a history of mixed incontinence (ie, OAB with UUI and stress incontinence) where the investigator determined that stress incontinence was predominant, patients at risk for urinary retention as determined by investigator, neurologic conditions associated with OAB (eg, multiple sclerosis), pregnant or breastfeeding or plans to do so during study, and prior use of vibegron before baseline visit.