Conclusion
PONV
ADVERSE EFFECT
Compared to OA technique, OFA technique, which is represented by non-opioid drugs esketamine and dexmedetomidine, may be an alternative anesthesia in gynecological laparoscopic surgery under ERAS protocol with its non-inferiority of analgesic effect, intraoperative anesthesia stability and lower incidence of PONV. Although OFA technique prolonged awakening and orientation recovery time, there was little adverse effect on the quality of anesthesia and recovery. Furthermore, it could improve postoperative sleep quality as a preliminary finding. For better clinical anesthesia effect, ERAS protocol and OFA technique need to be further optimized.