Design and ethical approval
In this randomized clinical trial, all patients signed an informed consent form before the intervention. The study protocol was reviewed and approved by the Ethics Committee of the Affiliated Rehabilitation Hospital of the Fujian University of Traditional Chinese Medicine (FJTCM) (No. 2017KY-010-02). FJTCM was responsible for the integrity and conduct of this study. The trial was prospectively registered in the Chinese Clinical Trial Registry (ref. ChiCTR1800015629).