4.3. Blood Sampling
inflammation, Peripheral venous blood
BLOOD, INFLAMMATION
Peripheral venous blood for either routine testing or small EV isolation was drawn at screening, day 0 at both 0 h and 6 h post-intervention, day 1, month 1, month 3, month 6, and month 12. Blood for routine testing was brought to the Department of Laboratory Medicine at the Medical University of Vienna, and measured according to current standards. Apart from the day of intervention at 0 h and 6 h post-intervention, regular blood testing included blood count, coagulation, kidney function, liver function, electrolytes, lipids, cardiac and inflammation parameters. At the intervention day, only cardiac biomarkers were evaluated. eGFR was calculated with the CKD-EPI 2021 formula [For small EV isolation, EDTA plasma was obtained and subjected to sequential centrifugation prior to the isolation (