Ethics approval and consent to participate
ChiCTR2100051130
This trial was approved by the Medical Ethics Committee of Jinhua Hospital Affiliated to Zhejiang University on 15 December 2020. Written informed consent was obtained from all patients. The study has been registered in the Chinese Clinical Trial Registry (ChiCTR2100051130, Principal investigator: Huayan Lv, date of registration: september 14, 2021). This study was carried out in accordance with the Consolidated Standards of Reporting Trials (CONSORT) 2010 statement and the Declaration of Helsinki.