Study setting
In contrast to the earlier EACDRP trial which had been conducted in Tanzania and Uganda, the current study (MeLoHanD) was conducted between January and December 2020 in Uganda only, in the same two central districts: (a) Wakiso district, which forms a horseshoe shape around the capital city of Kampala and includes urban, peri-urban, and rural areas with a population of 2.5 million; (b) Mpigi district, which lies just southwest of Kampala along the shores of Lake Victoria and has a population of 250,000 (Fig. 
Map showing the distribution of participating health facilities across Mpigi and Wakiso Districts in Uganda (developed using GPS visualizer.com). HC - Health centre levels II, III, IV. Hosp - Hospital