Study Model and Simulation
diabetes
EVENTS, DISEASE PROGRESSION, DIABETES
To estimate the cost-effectiveness of ON101 with GWC, a Markov state-transition model, which simulated the chronic and recurrent events in the disease progression of a DFU, was applied to consider a hypothetical cohort of patients with diabetes with a mean age of 57 years who had uninfected DFUs sized 1 to 25 cmThe Markov model in this study was adapted from existing validated decision-analytic models