Participants and study design
undernutrition, mandibular fracture
UNDERNUTRITION
The study subjects were patients in the Department of Dental and Oral Surgery of Saga University Hospital (Saga, Japan) who required maxillomandibular fixation either after orthognathic surgery or for the treatment of mandibular fracture between October 2019 and December 2022. The subjects were allocated by the envelope method to either the HABITPRO group or the placebo group. Patients with severe undernutrition (Alb ≤2.5 g/dL) or those who were unable to gargle unaided were excluded from the study (Table Exclusion criteria.
Having severe undernutrition from before the start of treatment (Alb ≤2.5 g/dL)
Unable to gargle independently
Considered by an investigator to be unsuitable to participate in the study for any other reasons