Biomarker analysis
CSF from participants was analyzed with the following assays: Elecsys β-Amyloid (1-42) CSF, Elecsys Total-Tau CSF and Elecsys Phospho-Tau (181P) CSF performed at Roche Diagnostics); NfL (Uman), NfH (Protein Simple, ELLA), YKL40 (Protein Simple, ELLA) and NRGN (Euroimmune) at Immunologix.