7. Discussion
postoperative pain, visceral pain, acute pain, pain, lung cancer, chronic pain
LUNG CANCER, CHRONIC PAIN
Our study revealed that CPVB can significantly reduce the chronic pain incidence and intensity at 3, 6, and 9 months after surgery and provide better acute pain relief up to 7 days after surgery when compared to local anesthetic continuous infusion but had no effect on long-term quality of life in patients with lung cancer. Our results may still promote the innovation of the postoperative analgesia mode of thoracic surgery and provide patients with better analgesia and faster rehabilitation quality after surgery.The complexity of postoperative pain can be caused by a variety of factors, including the operative wound, muscle splitting, chest tube stimulation, and visceral pain; the complexity of pain generators necessitates multimodal postoperative analgesia [Several studies have demonstrated that acute pain intensity is the strongest predictor of chronic pain [The reported prevalence of chronic pain after thoracic surgery is quite variable, ranging from 14.3 to 90% [Severe persistent postsurgical pain mandates the liberal use of painkillers, including opiates, which itself increases the risk of chronic pain emergence [To evaluate the long-term postoperative quality of life of patients with lung cancer undergoing thoracoscopic surgery, SF-12 was selected as the evaluation tool in this study. SF-12 was developed and validated as a generic short-form instrument for measuring health-related quality of life. The tool has been widely applied to assess important quality of life domains in medical studies [