Image acquisition and data preprocessing
Each participant completed two MRI scans: one at baseline and one within a week after completing the intervention. Both the baseline and postintervention scans were performed with a Siemens Prisma 3.0-Tesla system (Erlangen, Germany) located at one participating hospital. Scans included T1-weighted imaging, DTI, and resting-state functional MRI (fMRI). T1 images were obtained using a magnetization-prepared rapid gradient-echo (MPRAGE) T1-weighted sequence with the following parameters: 256 × 256 matrix size with 192 contiguous slices, 1 mm isotropic resolution, repetition time (TR) = 2530 ms, echo time (TE) = 2.51 ms, flip angle (FA) = 7°, field of view (FOV) = 256 × 256 mmPreprocessing of DTI data was conducted following the steps of the PANDA (