Vaccines and vaccination schedule
The QIV vaccine was formulated by PT Bio Farma (Persero), Indonesia, using bulks imported from Japan. The investigational QIV contained 15 μg HA from each of 4 strains, A/California/7/2009 (X-179A) (H1N1) pdm09n, A/Hong Kong/4801/2014 (X-263) (H3N2), B/Texas/2/2013, and B/Phuket/3073/2013, in a 0.5 ml dose, with batch numbers A: 3070117, B: 3070217, and C: 3070317. TIV contained 15 μg HA of each of 3 strains, A/California/7/2009 (X-179A) (H1N1) pdm09n, A/Hong Kong/4801/2014 (X-263) (H3N2), and B/Texas/2/2013, in 0.5 ml dose. Each subject received one dose (0.5 ml) of TIV or QIV with different batch numbers: 3070117, 3070217, and 3070317 for batches A, B, and C, respectively, according to the randomization.