Centres/investigators
All recruiting centres are university-based tertiary care centres with high-volume kidney transplant units. The local PIs at the participating trial sites are internationally recognised scientists in the field of kidney transplantation with a track record of the successful conduction of interventional clinical trials. The personnel involved in the clinical trial are qualified in accordance with the quality standards of ‘good clinical practice’. At each centre, appropriately trained medical staff will be available to provide the necessary standard of care for trial participants and provide medical care specific to the trial and beyond. The trial sites have a local laboratory or cooperate contractually with external service providers to be able to perform the laboratory diagnostics required for the trial in a qualified manner. The trial sites have Internet access to use web-based randomisation and complete data entry via an electronic case report form (eCRF).