Inclusion and withdrawal criteria
tooth
ADVERSE EVENTS
Participants in this clinical trial must meet all the following criteria:1) The subjects shall be over 18 years old (inclusive), regardless of gender; 2) The impacted mandibular third molars were showed mesioangular or horizontal, Pell &Gregory grade [Withdrawal criteria: All subjects who sign the informed consent form and are eligible to enter the study are shedding cases no matter when they withdraw from the study for any reason, as long as they do not complete the observation period stipulated in the protocol. (1) The subjects voluntarily quit the test for various reasons; (2) Due to adverse events, especially serious adverse events, the ethics committee considers suspending the study from the ethical and moral perspective; (3) If the bone materials need to removed or other treatment is necessary because of the adverse events during the trial; (4) It is necessary for the researcher to stop the study from the medical point of view; (5) Those who need to stop the experiment for other reasons.Before participating in the study, all subjects were informed of the purpose and operative process of the study and signed a tooth extraction informed consent and a study informed consent. The name, age, sex, operation note of the patients were recorded on the tooth extraction day.