Acknowledgements
We are deeply grateful to the patients involved in the study. We are grateful to study coordinator Ingunn Anundskås, and thank our technical laboratory staff, Martina Castelli, Sepideh Mostafavi, Yana Mikhaleva, Hanne Linda Nakkestad, and Gry Hilde Nilsen, for excellent technical assistance. We thank Prof Mathias Ziegler and Dr Brage Brakedal for the inspiring scientific discussions. We also thank Dr Ann Cathrine Kroksveen, Biobank Haukeland, Haukeland University Hospital. We are grateful to ChromaDex (Irvine, California) for providing the NR and placebo capsules for the study. The trial was supported by grants from The Research Council of Norway (288164, C.T.), Trond Mohn Foundation (BFS2017REK05, C.T.) and the Western Norway Regional Health Authority (F-11470 CT, F-12133 CT, F-12823 H.B.). The sponsor of the study is Haukeland University Hospital, who hosted the trial and provided the required facilities and personnel.