Patients and methods
We performed a prospective multicenter single-blind randomized controlled clinical trial. All patients due to undergo scheduled mastectomy with or without axillary lymph node dissection at Amiens Picardie University Hospital (Amiens, France), Compiegne General Hospital (Compiegne, France) or Soissons General Hospital (Soissons, France) were considered for enrollment. Patients were randomized into two groups: quilting suture or conventional wound closure. The study protocol was approved by the local institutional review board named 