Acute toxicities due to radiation
dysphagia, toxicities, skin toxicity
DYSPHAGIA, REGRESSION, SKIN TOXICITY
Reported acute toxicities were newly developed, with radiation associated dysphagia and skin toxicity. Analyses with logistic regression showed a lower risk for severe skin toxicity using IMRT or VMAT (OR = 0.2, 95% CI: 0.04–0.9) compared to conventional radiation (3D conformal or opposing field technique). (Table Analysis of acute toxicities using logistic regression modelsBold values identify significant results with OR = Odds Radio, CI = Confidence Interval, IMRT = Intensity Modulated Radiotherapy. VMAT = Volumetric Modulated Arc Therapy, p ≤ 0.05 = statistical significant The risk of dysphagia was lower if a radiation dose of at least 50 Gy was applied (OR = 0.2, 95% CI: 0.05–0.9).Multimodal therapy (combination of surgery, chemotherapy and radiotherapy) failed to show any significant effect on skin toxicity or dysphagia.