Statistical Analysis
depression
REMISSION
Data analysis in this clinical trial was conducted by an independent hired statistician, blinded to treatment groups. The sample size was designed to detect a 30% difference (experimental group, 60% and control group, 30%) in depression symptom recovery between the 2 groups. A minimum sample of 36 participants per group was estimated, considering the test as 2-tailed, with 80% power and a significance level of Initially, a baseline comparison between the SA and NSA groups was performed with median and IQR descriptions for continuous variables and frequencies and percentages for categorical variables. Subsequently, intent-to-treat and modified intent-to-treat analyses were conducted to compare the proportions of depression recovery and remission at different time points in the study using Fisher exact test. The effect size for dichotomous variables was calculated as relative risk.Scores were subjected to a normality test that rejected the normality hypothesis to verify sample normality. Therefore, nonparametric tests were adopted. The reduction of depression scores over time in both groups was evaluated using the median and IQR. The statistical analysis of these data was conducted using the Wilcoxon-Mann-Whitney Cochran 