Funding
handling/analysis
This work was supported by a grant from Japan Agency for Medical Research and Development (grant number 16lk0201052h) and the Tokyo University Research Fund. In addition, Yakult Honsha Co., Ltd. provided oxaliplatin, irinotecan, and leucovorin free of charge for this study. However, this study was independent from the sponsor and investigators have responsibility for study conception, design, data handling/analysis, subsequent publication.