Funding
This publication presents independent research funded in part by the National Institute for Health Research (NIHR) via the Research Professorship award (NIHR300026) to AJD, the NIHR Leicester Biomedical Research Centre which is a partnership between University Hospitals of Leicester NHS Trust, Loughborough University and the University of Leicester, and Loughborough University via CJM’s Doctoral Prize Fellowship. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, the Department of Health and Social Care or Loughborough University. The funding bodies did not have any role in the design of the study, collection, analysis, interpretation of findings, or writing of the manuscript.