Verification of our criteria in the validation cohort
SECONDARY
In the validation cohort, PMX-HA use in the full sample did not significantly improve 28-day survival (28-day survival rate in the PMX-HA group vs. in the control group, 70% vs. 62%, + 7.4% [95% CI − 4.3% to + 19%], As for the secondary outcomes, using the Cox proportional hazard model, we found a significant difference in the adjusted survival time to 28 days between PMX-HA versus control in the targeted population of the validation cohort (hazard ratio [HR] 0.62, 95% CI 0.40 to 0.95, 