RANDOMISATION
bleb’, comorbidity
The computer-generated randomisation list was prepared by an independent statistician, and we used web-based randomisation, accessed by study staff following consent and baseline assessment. Randomisation was stratified by study region, age (<40 years; 40 to 59 years; ≥60 years) and presence/absence of medical comorbidity. Participants, investigators, outcome assessors, data managers, trial statisticians and trial staff were blinded to the randomisation group throughout the trial. A photo was taken of the injection site ‘bleb’ to confirm correct administration.