Docetaxel and epirubicin induce different forms of cell death
death, breast cancer
HEAT, BREAST CANCER
To investigate the source of the D-induced immunomodulatory factors we performed in vitro experiments. WBCs, breast cancer cell lines and a combination of both were exposed for 72 h to either epirubicin or docetaxel. PBS served as negative control. Then the above-mentioned 14 factors were measured in the supernatant. The heat map in Fig. Effect of docetaxel, epirubicin, and cyclophosphamide on in vitro cultures of breast cancer cells. To investigate the respective cell death pathways, we compared the cytotoxic effects of docetaxel, epirubicin and 4-OOH-CY on six breast cancer cell lines. Figure 