Statistical Analysis
virologic suppression
This analysis was conducted to examine the association of self-reported adherence with maternal viral load suppression. The primary exposures of interest for this analysis were (1) self-reported adherence to mART and (2) self-reported adherence to iNVP for infants in both arms. The outcome of interest was lack of maternal virologic suppression defined as maternal viral load (mVL) of > 400 or > 1000 copies/mL at least 6 weeks after randomization.The adherence responses were analyzed using dichotomous and continuous measures of adherence. A dichotomous measure of adherence was defined as missing any of the ART medication within a 4-, 2-, and 1-week period of each visit. A continuous measure of adherence at each visit was the proportion of missed doses within 3 days before study visit, defined as the total number of doses missed/total number of doses expected within a 3-day period at each visit. The dichotomous measures of adherence were combined across visits to get an overall measure of adherence. A χ