Methods
atopy
ATOPY, SECONDARY
Healthy term infants with no family history of atopy and whose mothers decided to exclusively formula feed were randomized to be fed either CMF (Enfamil™, Mead Johnson Nutrition; At each of 14 study visits from 0.5 to 12.5 months, infants were weighed in triplicate by trained research personnel using calibrated infant scales accurate to 0.001 kg and mothers prospectively recorded their infants’ intake of formula and, if applicable, types and amounts of all other liquids and foods. The baseline (0.5 month) visit occurred before randomization (0.75 months) and all infants were fed CMF during the interim. Three-day records were obtained at 0.75, 3.5, and 12.5 months during which formula intake was determined by 3-day weighed bottle intake whereas 1-day diet records were obtained at all other visits. Returned records were reviewed for quality by registered dietitians and deemed not usable if insufficient information (e.g., amounts) provided.In this secondary analysis, we analyzed the diet records to determine glutamic acid intake from infant formula and other food sources by using the Nutrition Data System for Research (version 2019) software and established food categories [