Efficacy indicators
sore throat, sinusitis, pneumonia, fever, fatigue, muscle soreness, myocarditis, cough, nasal congestion, headache, chills
SORE THROAT, SINUSITIS, PNEUMONIA, ADVERSE EVENTS, MYOCARDITIS, OTITIS MEDIA, REMISSION, DISEASE, COMPLICATIONS, INFLUENZA
(1) Time to fever relief (the time, after medication, for the axillary body temperature to drop to < 37.3 °C for 24 h). Time to relief of influenza symptoms: nasal congestion, sore throat, cough, muscle soreness, fatigue, headache, chills, sweating, and other influenza symptoms were relieved (ISS score was reduced to 0 or 1), and the time required for remission to last for at least 24 h. (2) Disease severity: The area under the curve (AUC) of the total score of influenza symptoms was used as the evaluation index, and the total score of influenza symptoms twice a day was plotted with the median time (h) to calculate the AUC, and the difference between the two groups in the total symptoms score was counted. (3) The incidence of influenza-like complications (sinusitis, otitis media, myocarditis, pneumonia) and adverse events.This study was approved by the Scientific Research Ethics Committee of the Second Hospital of Hebei Medical University (No.2020-C044-X01).