2.3. Data Analysis
overjet
REGRESSION
Means with their respective standard deviations were reported for continuous variables, while frequencies followed by their proportion and 95% confidence intervals were reported for categorical data.To statistically quantify the extent to which the effect of breastfeeding (exposure) on overjet (outcome) was mediated by the use of a pacifier after accounting for measured confounders (Firstly, we used logistic regression modeling to regress the presence of increased overjet at the age of 12 years on breastfeeding over 12 months, use of a pacifier at 12 months, and the covariates (continuous covariates, including birth weight, length at birth, head circumference at birth, and maternal age at childbirth; categorical covariates, including maternal schooling and income). Secondly, we fitted a logistic regression model to regress pacifier use on breastfeeding at 12 months and the covariates. These procedures were conducted using the CMAverse macro [Finally, we performed sensitivity analyses using the E-value estimate to test potential unmeasured confounding (U) [