Radon spa and thermal spa treatment significantly decrease osteoclastogenesis and resorbed area on bone slices
bone erosion, pain
BONE EROSION
Radon spa treatment shows significantly reduced pain and a systemic decrease of markers related to bone erosion in the blood and serum of radon exposed MSDs patients in previous studies (For this purpose, patients’ blood was collected at different time points (before (0), 4, 12 and 24 weeks) (see After radon spa treatment (Reduced terminal differentiation and activity of bone resorbing osteoclasts (OCs) after radon and thermal spa treatment. The total number of OCs was significantly increased after radon spa Notably, for both, radon and thermal spa treatment, a modified differentiation was observed, but the effect after radon spa treatment on the differentiation into mOCs was more pronounced and at a higher level of significance compared to thermal spa treatment, in particular for 4 and 24 weeks after radon spa treatment (