Patient population
stroke, sub-arachnoid hemorrhage, Stroke
STROKE, STROKE, DIABETES MELLITUS, COMPLICATIONS
Of the 133 patients that received both 24-hour and 1-week NCCT scans in the MR CLEAN-NO IV trial, we excluded patients with poor image quality (n = 10), old lesions (n = 5) and other complications (sub-arachnoid hemorrhage: n = 1 and craniectomy: n = 1); thus, analyzing 116 patients in this study. (Flowchart is presented in the Supplementary Material.) The median age of the included population was 71 (IQR: 59–76) years, and 43 (37%) patients were female. Eleven percent of the population had suffered from a previous stroke and 18% presented a history of diabetes mellitus. The median NIH Stroke Scale (NIHSS) and ASPECTS at baseline were 16 (IQR: 11–19) and 9 (IQR: 8–10), respectively. Fifty-three (46%) patients were randomized to undergo direct EVT without the administration of intravenous (IVT) thrombolytic. Successful reperfusion (eTICI:2b-3) was achieved in 90 (87%) patients and 57 (49%) patients achieved a favorable functional outcome. Baseline characteristics of the patients included in this study are provided in Baseline, imaging, treatment, and post-treatment characteristics along with a comparison between patients randomized to receive or not receive iv-TPA before IAT.Data are displayed as median (interquartile range) or number (%population). Missing information, when applicable, is also provided as number (%population). Mann-Whitney U test and Chi-Square/Fisher tests were performed to compare continuous and binary/categorical variables between the sub-groups based on treatment allocation appropriately.The baseline, treatment, and follow-up characteristics of the patients included in this study are comparable to those of the complete MR CLEAN-NO IV trial population. (Supplementary Table 1). Furthermore, these characteristics were also comparable between patients included in this study and those that received the MRI-workflow at follow-up. (Supplementary Table 2).