4. Conclusions
psoriasis
INFLAMMATION, PSORIASIS
According to our findings, probiotic and prebiotic supplementation enhanced the general health of patients with psoriasis who were receiving local anti-psoriatic treatment. First, probiotic and prebiotic supplementation significantly improved quality of life, as demonstrated by a reduction in PASI and DLQI scores. Second, the BMI and FFM of patients in the intervention group were significantly reduced (end of trial versus baseline). Third, prebiotic and probiotic (Overall, our study showed that spore-based probiotic and precision prebiotic supplementation in patients with psoriasis who were receiving adequate anti-psoriatic therapy experienced multiple improvements, including improvements in quality of life, inflammation, and gut microbiota dysbiosis. However, additional clinical trials are needed to fully elucidate the potential benefits of probiotics and prebiotics for psoriasis and to identify the most effective combination and dose. 