Strengths and Limitations
The present study has several strengths. First, the study population was obtained from the PLATO trial, a large randomized control trial in which patients were carefully included and monitored. Second, we studied an international cohort with MINOCA, because the PLATO trial included patients from 862 centers in 43 countriesThere are also some limitations to our study. First, the study cohort stems from a randomized control trial and, thus, probably represents a healthier subset of the general population with MI.