Baseline characteristics
In total, 110 subjects were enrolled in the DOP, with optimized doses achieved for 107 patients. The Details of the demographics and baseline characteristics for the population have been reported in detail previously. Briefly, 69% of patients were male, and weight, height, and body mass index were balanced across treatment sequence groups. Mean (standard deviation [SD]) baseline ADHD-RS-IV total score for the Safety Population (all patients receiving at least one dose of study medication and having at least one postdose measurement) was 38.3 (8.6), assessed before the start of the DOP (Cutler et al., 