Study design
aneurysm rupture, aneurysm, aneurysms
ANEURYSM, RECRUITMENT, ANEURYSMS, ANEURYSM RUPTURED, COMPLICATIONS, INTRACRANIAL ANEURYSMS
This study is a subgroup analysis of Catch data obtained from a prospective, multicenter, open-label, randomized controlled trial that includes patients treated with the Numen and Axium coil. The CATCH clinical trial includes patients treated with the Numen or Axium coil starting in August 2017 and concluding in December 2019, following the enrollment of 350 patients. The data of 140 patients whose aneurysms were smaller than 5 mm were extracted from the CATCH trial in this subgroup analysis. Details regarding the institutional review board and ethics committee approvals, patient population, and protocol requirements are described in the primary CATCH article.This subgroupanalysis was performed to assess the safety and efficacy of the Numen coil Embolization System in treating of small intracranial aneurysms (< 5 mm) compared with the Axium coil. Data for analysis were basic demographic information, including patient age, sex, and history of aneurysm rupture; aneurysm characteristics, including aneurysm size and location; procedural data, including packing density, devices used; and follow-up data, including any complications. Before commencing recruitment, the study was registered with the China Clinical Trial Registry (NCT02990156).