DISCUSSION
AD
CORTEX
So far, there have been limited studies focusing on resting‐state network modifications caused by neuro‐navigated rTMS therapy in AD. Our findings indicated that rTMS intervention could improve cognition at the targeted location of the left angular cortex (MNI: −45, −67, 38). In addition, this study reveals a potential modulation mechanism of DMN subsystems and the large‐scale functional networks associated with the DMN in cognitive improvement. Moreover, dynamic regulation of the intra‐ and inter‐DMN at baseline may be assessed as a potential predictor of favorable rTMS treatment response in AD patients.