Cost-effectiveness methods
EVENT
A cost-effectiveness analysis was carried out based on a decision tree model from the health system's or third-party payer's perspectiveCosts included in the model and probabilities.Furthermore, it was calculated the incremental cost-effectiveness ratio (ICER). This ratio indicates the additional cost for each unwanted event avoided. To inform the health decision-making process, the ICER was compared to a cost-effectiveness threshold. The model used the threshold recommended by the WHO of up to three times the GDP per capita for Colombia, which, according to the World Bank, was USD 5805.61 (2016), USD 17,417. With the average exchange rate (TRM) of 2017 at COP 2939.63. So, the equivalent threshold was COP 51,199,052.04.The time horizon was less than 1 year, and the cost-effectiveness threshold was three times the GDP per capita (around 50 million of COP, equivalent to 17,012.58 USD, 2017). Uncertainty was controlled with deterministic and probabilistic analyses using a Monte Carlo simulation.