Statistical analysis
SCLC
SCLC
The sample size consideration was based on the unilateral exact test with α = 0.05 (unilateral), β = 0.20, and the second-line standard treatment plan recommended by the current guidelines for topotecan single-agent treatment of refractory SCLC patients with ORR of 9.4% [Means, standard deviations, medians, maxima, and minima are listed for measurement data, and frequencies (composition ratio), rates, and confidence intervals are listed for count data and rank data. Statistical analyses were carried out with statistical software package SPSS 24.0. The mean, standard deviation, median, maximum and minimum values of quantitative data, such as age, height and weight are calculated for basic patient characteristics. The frequencies and percentages are listed for qualitative data, such as gender and ECOG scores.