DISCUSSION
tumor
ADVERSE EVENTS, SECONDARY, TUMOR
[For safety, adverse events were monitored using clinical evaluation and blood analysis. In addition, cytokine and ferritin levels were measured in blood, because these can rise in cases of macrophage activation (The biodistribution data are in line with the preclinical results (Fast blood clearance was confirmed for [Whole-body and organ dosimetry was performed to assess the radiation burden on the patients. The kidneys received the highest organ dose, which was well below thresholds for deterministic effects. With an average effective dose of 2.2 × 10Other research groups have used mannose-based radiotracers for imaging of CD206-positive macrophages. Tahara et al. reported on 2-deoxy-2-[As a secondary and exploratory objective, tumor uptake values of [