Conclusion
PBC
DISEASE, PBC, COMPLICATION
The results of the present study showed that the design and implementation of the TPB-based medication adherence training program could produce a significant difference in the level of knowledge, attitude, subjective norms, behavioral intention, PBC, and performance of the patients in the case group.In the current study, by increasing patients' attitudes toward medication adherence outcomes, increasing their perceived ability in this regard, and simultaneously using the effect of subjective norms (physician, nurse, and family) along with patients' active follow-up, a significant increase in the average performance of adherence.This result should be considered by the healthcare professional when training educational program and evaluating the risk of non-adherence with therapies in patients with MS. It is essential to implement efforts to improve treatment adherence, disease care, and patients’ quality of life and to reduce public health costs for MS patients.However, whether patient’s behavioral changes (promotion TAD) directly have clinical implications for the prevention of adverse out come and complication of MS, requires further studies. In other words, more evidence is needed to show that TPB can actually be effective in decrease outcome of disease in patients with MS. It is suggested that future studies be designed to use laboratory tests in addition to questionnaires to assess the (worse or better disease) impact of health behaviors.