5. Conclusions
MetS, RYGB-induced weight loss, weight loss
SEVERE OBESITY, OBESE
Taken together, our results allow us to conclude that the weight loss promoted by BS in female patients with severe obesity presenting or not presenting with MetS could remarkably improve anthropometric, biochemical, and systemic inflammatory variables, especially the ratio of adiponectin to leptin. Furthermore, our data, in conjunction with previous reports in the literature, can reinforce to the scientific community the importance of the adiponectin to leptin ratio as an emerging inflammatory biomarker, particularly for cardiometabolic risk. Another detail to be highlighted was the impact caused by RYGB-induced weight loss on the inflammatory profile of severely obese patients with and without MetS.