Measurements and procedures
DISEASE PROGRESSION
At baseline, medical history and symptoms were collected. Additionally, physical examination, blood analysis (hematology, biochemistry, hepatic and renal), pregnancy test, imaging (CT scan thorax-abdomen-pelvis), echocardiography and an ECG were conducted.For patients without disease progression, imaging was repeated every 3 months. After progression, survival status and documentation of further antineoplastic treatment was conducted every 6 months.