16S rRNA gene sequencing analysis of gut microbiota in the study subjects
HTN
HTN
After 16S rRNA gene sequencing, the species accumulation curve of GM in Fig. 
The basic information of the 16S rRNA gene sequencing. The species accumulation curve of gut microbiota detected in HTN and control subjects in this study (Initially, we evaluated the α-diversities of GM in females and males, which were significantly lower in males compared with females (Fig. 
The diversity analysis of gut microbiota in the study subjects. Violin plots of α-diversity analysis in different comparison groups: females vs. males (The differences of GM composition between HTN and control subjects were taxonomically evaluated at six different levels, including phylum, class, order, family, genus and species, and the top 10 GM taxa with higher relative abundances were summarized in each level (Fig. 
Relative abundances and comparative analysis of the taxonomic composition of gut microbiota in the study subjects. Relative abundances and comparative analysis of the taxonomic composition of gut microbiota in the enrolled females (
Linear discriminant analysis (LDA) effect size (LEfSe) analysis of gut microbiota taxa in the study subjects. LDA scores indicate differentially represented taxa in HTN and control groups in females (