Randomization
Depression
REMISSION, BLIND
Randomization was based on computer-generated treatment allocations prepared by independent personnel. Participants who met remission criteria at the end of step 1 were randomized to SPS or monitoring; those who did not remit were randomized to CBCM or SPS. Assessors were blind to treatment allocation. Participants in the nonremission arm of the trial were randomized a second time based on remission status at the end of step 2. Those who remitted were randomized to SPS or monitoring; those who did not were randomized to CBCM with fluoxetine or CBCM with placebo, stratified by Montgomery-Åsberg Depression Rating Scale (MADRS) total score (lower than 21 vs 21 or higher). In step 3, assessors and participants were blind to treatment allocation.