Conclusions and Relevance
stroke, hypertension, coronary heart disease
CVD, STROKE, CORONARY HEART DISEASE, SECONDARY, HYPERTENSION
In this secondary analysis of a randomized clinical trial in an adult population with hypertension and coronary heart disease risk factors, CVD mortality was similar between all 3 groups. ACE inhibitors increased the risk of stroke outcomes by 11% compared with diuretics, and this effect persisted well beyond the trial period.