Trial design and participants
tumour
TUMOUR
This thromboxane biosynthesis study was embedded within the randomised Add-Aspirin trial framework. The Add-Aspirin protocol encompasses four individually powered, Phase III, adjuvant studies in four different tumour types, i.e., breast, colorectal, gastro-oesophageal and prostate. Full details of the trial have been published previously [All participants (The trial protocol, including the thromboxane biosynthesis study, was approved by South Central-Oxford C research ethics committee (Ref: 14/SC/0171) and by local research and development departments at all centres. Participants provided written informed consent.