Author contributions
L.J., L.Q. and H.D. designed the study. L.J., H.J., Z.C., W.Q., L.Liao., Y.Z., X.L., S.P., L.Z., L.C., T.Y., Y.L. and S.Q. did the trial and collected the data. J.W., J.G., Y.W., L.Li. and Q.M. analysed the data. L.Q., H.D., J.W., J.G., Q.M. and H.H.-Z. interpreted the data. Q.M. and H.H.-Z. wrote the manuscript. L.J., L.Q. and L.Li. assessed and verified the data. All authors had full access to all the data in the study and had critically reviewed the manuscript and approved the final manuscript. All authors vouch for data accuracy and fidelity to the protocol.