Ethics considerations, setting, and patients
CAVITY
The study was approved by the Ethics and Research Committee of North Khorasan University of Medical Sciences Review Board. The trial was also registered and approved in the registry of clinical trials (IRCT20190123042475N1 and IRCT20190123042475N2). All the patients who took part in this study were provided informed consent prior to participation in the study. In this trial, we included patients over 18 years old undergoing RT with a minimum radiation dose of 30 Gy for the first time and when the oral cavity was in the range of radiation.