5. Conclusion
CIPN, breast cancer
BREAST CANCER
In conclusion, we demonstrated that cryotherapy reduced the incidence of persistent CIPN numerically and ≥ age 66 was a risk factor for persistent CIPN in breast cancer patients receiving weekly paclitaxel-based chemotherapy. A prospective randomized trial with a long-term period is needed to confirm the preventive effect of cryotherapy on persistent CIPN.