PrEP adherence
Among the 53 participants with available adherence data, the mean number of days on PrEP was 156.4 (SD 48.0) in the intervention arm and 167.3 (SD 57.3) in the control arm. Only three participants (5.7%) had high PrEP adherence over the duration of PrEP use, all of whom were in the intervention arm, so we were not able to estimate intervention effects. The mean number of days with a Wisepill opening over the duration of PrEP use was 42.4 (SD 53.0) in the intervention arm and 22.8 (SD 27.4) in the control arm, corresponding to 24.9% and 13.0% of the number of days on PrEP, respectively (adjusted incident rate ratio [aIRR] 1.94; 95% CI 1.16–3.25; 