Background
NAFLD, T2DM, cardiovascular disease, metabolic disorder
CARDIOVASCULAR DISEASE, METABOLIC DISORDER, MYOCARDIAL DYSFUNCTION, NONALCOHOLIC FATTY LIVER DISEASE, ATHEROSCLEROTIC CARDIOVASCULAR DISEASE, TYPE 2 DIABETES MELLITUS
Nonalcoholic fatty liver disease (NAFLD) is a complex metabolic disorder that increases the risk for cardiovascular disease in patients with type 2 diabetes mellitus (T2DM). Global longitudinal strain (GLS) is an indicator of left ventricular (LV) mechanics and can detect subclinical myocardial dysfunction. We compared the effects of pioglitazone and empagliflozin on GLS in patients with T2DM and NAFLD without established atherosclerotic cardiovascular disease.