Objectives
tumor
SECONDARY, ADVERSE EVENT, TUMOR, HER2-NEGATIVE BREAST CANCER
The primary objective was to evaluate the safety and adverse event profiles of immunotherapy combined with T-VEC in patients with localized HER2-negative breast cancer. The secondary objective was to assess the potential efficacy and pathologic response to nivolumab, ipilimumab, and T-VEC by measuring the tumor size and by descriptively analyzing the tumor on histopathologic examination after definitive surgery.