Background
death, pain, gait disturbances, OSCC, neurosensory deficits
ADVERSE EFFECTS, DISEASES, ORAL SQUAMOUS CELL CARCINOMA
Oral squamous cell carcinoma (OSCC) is the sixth most common cause of death among all cancer-related diseases with an increasing incidence, [In surgical treatment of OSCC, tumor-free resection is aspired and therefore radical surgery is performed [After the introduction of microsurgical techniques, different donor-sites were described for harvesting of osteocutaneous free flaps [Due to the widespread use of computed tomography (CT) and computer-assisted image processing, the options for preoperative planning have improved significantly in recent decades [Besides considerations focusing on the oncological as well as the functional and aesthetic outcome of the stomatognathic system, comorbidities of the donor-site have to be taken into account. Current literature report controversial results regarding donor-site morbidity after harvesting of DCIA graft and is mostly based on retrospective reviews of medical records. Chronic pain, gait disturbances and neurosensory deficits are only a few of the known adverse effects described in the context of DCIA graft reconstructions [The first objective of this study is to investigate the extent of donor site morbidity in a study group receiving CAD/CAM driven DCIA graft reconstruction of the mandible to allow comparison with existing publications reporting donor site morbidity in conventional cases. The second aim of this study is to assess if there is a correlation of the graft volume or the incision length with postoperative donor-site morbidity following CAD/CAM driven DCIA graft harvesting. For this purpose, thorough chart review, evaluation of imaging data and postoperative physical examination was performed.