3.2. Iron Metabolism and Nordic Walking
cancer, infection, MM
INFECTION, CANCER, DISEASES, IRON OVERLOAD
Nordic walking is an activity with well-documented beneficial effects on various biochemical parameters of blood, including iron metabolism [The observed changes in serum Fe and gene expressions may be associated with a decrease in the labile iron pool (LIP), and therefore they should be considered beneficial, as free Fe ions are susceptible to oxidation and participate in the Fenton reaction, generating free radicals. An increase in LIP leads to an increase in ferritin levels in cells. According to the literature, High iron stores are associated with an increased risk of developing various non-communicable diseases, including cancer. Iron overload is also linked to a significant increase in the risk of infection in patients undergoing auto-HSCT procedures, which are often used in the treatment of MM [In our own study, no changes in serum transferrin concentrations, which is responsible for delivering iron to erythroblasts [