5. Conclusions
cardiometabolic dysfunction, endothelial dysfunction, diabetes
METABOLIC SYNDROME, INSULIN RESISTANCE, ENDOTHELIAL DYSFUNCTION, DIABETES
Our clinical study supports the role of strawberry supplementation in improving the serum metabolic profiles associated with decreased risks of insulin resistance and diabetes, as well as endothelial dysfunction in adults with features of metabolic syndrome. The significant decreases in the targeted metabolites, such as serum BCAAs, as well as significant increases in untargeted metabolites, including serum phosphate, benzoic acid, and hydroxyphenyl propionic acid, represent underlying pathways involved in reducing the risks of cardiometabolic dysfunction. Thus, adding whole strawberries to the habitual diet may be a beneficial and feasible strategy to improve the cardiometabolic health of adults.