Treatment effect of LPI combined with LPIp
humour, Angle-Closure, TIA, PACG
REGRESSION, HYPERTROPHIC, TIA
In PACD, the iris blocks the channel draining aqueous humour, thereby causing acute or chronic IOP increases. Previous PACD treatment mainly comprised LPI, which uses a laser to establish a new drainage channel in the iris to relieve the blockage. However, it was discovered in the Zhongshan Angle-Closure Prevention Trial that eyes with suspected PAC had residual angle closure after single iridotomy and the greater angle width following iridotomy further decreased as time went on.[PACS is considered a risk factor for PAC and PACG. Though in Handan eye study only lower than 10% of PACS found by health examination developed into PAC or PACG, logistic regression analysis identified narrower mean angle width to be associated with the progression. [Therefore, in this study, we used LPI combined with LPIp to treat PACS and PAC in patients with plateau iris or hypertrophic peripheral iris.LPIp was first proposed in the 1970s [After LPI combined with LPIp treatment, the IOP of all enrolled patients was significantly decreased compared to that before surgery. The results regarding the IOP-lowering effects of LPIp differ among published studies. Lee et al. found that the IOP values of patients treated with either LPI alone or LPI combined with LPIp were not significantly decreased at 1 h, 1 day, 1 week, 1 month, and 3 months after surgery [Our study results showed that after LPI combined with LPIp, the central anterior chamber depth was not significantly increased, whereas the peripheral AOD, TIA, and anterior chamber volume were. Numerous studies have shown that LPI alone or combined with LPIp can deepen the central anterior chamber [However, when comparing every two groups, the anterior chamber volume of HENP was larger than that of HEFP. This indicates that the higher energy is and the closer the laser point is to the periphery, the stronger the effect is on the increase in anterior chamber volume. When the laser energy is low, the selection of the spot position does not affect the anterior chamber volume. At present, clinical research has not reported on this phenomenon, but an animal experiment came to the same conclusion as the current study [