Conclusions
MCI, cognitive impairment
BRAIN
EOmciSS is a new, computerized, cognitive screening test designed for use by community-dwelling older adults. The test content, user interface, and administration method enable older adults to complete the test with a smartphone or tablet within 10 minutes. The test constructs of EOmciSS can be factored into Acc and RT components, both of which contributed significantly to the ability of EOmciSS to differentiate individuals with MCI risks from those with NCF. The screening ability of EOmciSS was revealed to be the strongest among other computerized tests, with comparable test constructs and time needed for completion. EOmciSS could serve as a first-line test for identifying individuals with MCI risks in the community. Application of EOmciSS could enable rapid, inexpensive, large-scale screening among older adults. Individuals who receive positive screening results should be followed up with more comprehensive neuropsychological and medical tests before confirmation of an MCI diagnosis.We thank all participants in the study as well as research staff for coordinating the research work and data collection. This study was funded by the Central Government Guides Local Science and Technology Development Fund Projects of Fujian Province (2020L3013) and the Peter T. C. Lee endowed professorship awarded to CCHC. Special thanks to Xiehua Xue and Sufang Cai for their support in assessing the participants for mild cognitive impairment diagnosis.Authors' Contributions: JW, J Tu, and ZL equally contributed to this work. CCHC, TMCL, and LC are the co-corresponding authors. JW, J Tu, ZL were responsible for data collection, data analysis, and writing. LC and YH took care of data curation and writing the manuscript. JH and J Tao were responsible for the methodology, review, and writing of the manuscript. CCHC, TMCL, and LC contributed to funding acquisition, manuscript review and editing. All authors have read and approved the final version of the manuscript.Conflicts of Interest: This study was sponsored by Amity Brain Health and A.I. Technology Company Limited (which develops EOmciSS) and CCHC and TMCL are paid research consultants for these organizations.Descriptions of the Participants.Descriptions of test content of EOmciSS (Efficient Online MCI Screening System).