Patients’ symptoms and HRQOL at start of study
CML, Fatigue
CML
The mean MDASI-CML symptom severity score at baseline was 2.0 points, indicating that overall symptoms reported by patients before the start of treatment were of a relatively low severity. Fatigue was the most severe symptom reported at baseline with a mean score of 3.9 points. Patients reported that CML interfered with their daily life slightly; the mean symptom distress score was 2.3 points, and work, mood, and general activity were noted to have the most interference out of the six interference items (Fig. 