Grouping, treatment, and follow-up
ADVERSE EVENT
The Jiading Branch of Shanghai General Hospital (Jiading District, Shanghai) carried out the centralized and randomized allocation of patients to either the conventional treatment group or the vitamin B6 supplement treatment group, in a 1:1 ratio. All randomization information was stored securely and only authorized personnel could access it. The data was managed by specialized statisticians. The patients in the conventional treatment group were instructed to take oral rabeprazole enteric-coated tablets 10 mg twice a day, metronidazole tablets 400 mg three times a day, minocycline capsules 100 mg twice a day, and bismuth potassium citrate capsules 220 mg twice a day. The study patients in the vitamin B6 supplement treatment group received oral doses of vitamin B6 20 mg twice a day in addition to the drugs used in the conventional treatment group. The treatment of the two groups was ended after 2 weeks. And the study patients were asked to return at the end of eradication therapy to take a At the beginning of the screening period, the patient demographics were recorded. Vital signs, physical examinations, and clinical laboratory tests were performed. Adverse events, concomitant medications, and treatment compliance were also assessed.