5.6. Statistical Analysis
All statistical procedures were performed with IBM SPSS Statistics 26.0.0 (IBM Co., Armonk, New York, NY, USA) software. Numerical variables were expressed as the mean (±standard deviation). Normality was determined using the Shapiro-Wilk test. Descriptive analysis was analyzed through Fisher’s exact test. Pre- and post-treatment measurements were first analyzed with non-parametric Friedman’s test (numerical variables) and Cochran’s Q test (binary variables) for each group. Then, the two groups were compared with the non-parametric Mann–Whitney U test for each checkpoint. The statistical significance threshold was 