Women with PCOS
bleeding, PCOS, amenorrhea
BLEEDING
Before and after the 4-month intervention, the women with PCOS underwent a physical examination on menstrual cycle day 6-8. In women with oligo- or amenorrhea, a bleeding was induced by taking 10 mg medroxyprogesterone for seven days. A thorough medical history was taken, anthropometric measurements were obtained, a gynecological examination including transvaginal ultrasound was completed and fasting blood sampling was carried out allowing for analysis of hormones, binding proteins and metabolic variables. The participants also filled in a questionnaire assessing the psychological general wellbeing index (PGWBI) at baseline and 4 months.