Sequence generation {16a}
AKI
Patients will be randomized in a 1:1 ratio to the TIPS or the SOC group. The randomization will be stratified according to the AKI stage (II or III) and sites. Randomization will be restricted by randomly varying block size and stratification by center. A computer-generated randomization list will be prepared by an independent statistician not involved in enrolment and analyses using the software nQuery Advisor. Randomization of a patient will be done by the site via an online tool of ZKS Jena (PaRANDies) to ensure that group assignment is unbiased and concealed from patients and investigator staff.