Introduction
colorectal cancer, constipation, adenoma
COLORECTAL CANCER, ADENOMA
The incidence of colorectal cancer increases in Thailand annuallyHigh-quality colonoscopy is important for colorectal screening. The current recommendations defined a high-quality colonoscopy according to various factors, such as an adequate adenoma detection rate (ADR > 30% in men and > 20% in women) and examination-specific characteristics (complete to caecum ≥ 95%, adequate bowel preparation to detect lesions > 5 mm)Chronic constipation affects cleansing during bowel preparation. A foreign study on the preparation of the large intestine in people with constipation showed that split-dose polyethylene glycol electrolyte lavage solution (PEG-ELS) could clean the colon by approximately 81.4%Lubiprostone was approved by the US Food and Drug Administration in 2007. It is used to treat constipation by activating chloride channels (ClC-2 channels), which increase the amount of fluid within the intestine without severe complicationsThe current guidelines do not suggest any specific bowel preparation in constipation patients