HCQ inhibited B cell proliferation but not T cell proliferation in vitro
PROLIFERATION
PBMCs were stimulated with phytohemagglutinin (PHA) or monoclonal anti-CD40 with CpG-B to induce T cell and B cell proliferation, respectively, in the presence of a dose range of HCQ. No effect of HCQ was seen on T cell proliferation (Fig. HCQ dose-dependently inhibited B cell but not T cell proliferation in vitro. PBMCs from 6 healthy donors were stained with CTV and stimulated for 5 days with 5 μg/ml PHA for T cell proliferation (