Introduction
depression, PMDD, mood disorders, premenstrual dysphoric disorder
A potentially disabling condition, premenstrual dysphoric disorder (PMDD) causes extensive personal suffering, occupational impairment, and disruption of interpersonal and family relationships. While 20–80% of women report mood, cognitive, and behavioral disturbances associated with their menstrual cycle (Hamilton et al. A single night of total or partial “wake therapy” (WT) (previously called therapeutic sleep deprivation) produces a rapid, albeit transient, antidepressant response in 40–60% of patients (Giedke and Schwarzler Light treatment sustains wake therapy benefits often lost after recovery sleep, and wake therapy hastens and potentiates light treatment effects taking 5–10 weeks to significantly improve mood in peripartum non-seasonal depression (Corral et al. As misaligned circadian rhythms characterize mood disorders (Goel et al. 