Ethics Approval
The study protocol and instruments were reviewed and approved by the Ethical Review Committee of the Peking University in 2018. The identification code is IRB00001052-18039. The study was conducted in accordance with the guidelines of the Declaration of Helsinki. Before the start of the study, all the participants read and signed an informed consent form voluntarily. The study protocol was registered in the Chinese Clinical Trial Registry (ChiCTR190023355).