Informative priors
To explore the potential impact of informative priors in STE–PoS, we have additionally simulated scenario 1 with more informative prior distributions. In order to derive these priors, survival data of 10 patients was assumed to be available from a pilot study, of which 5 patients had survived at least up to 12 months, therefore supporting an optimistic expectation toward the trial’s outcome. The posterior distributions of the conditional survival probabilities were assessed. Using the R package 