1. Introduction
hypoxia
HYPOXIC, HYPOXIA, OXIDATIVE STRESS, HYPOXIC
Previous studies have shown tart cherry (TC) to improve exercise performance in normoxia. The effect of TC on hypoxic exercise performance is unknown. This study investigated the effects of 5 days of tart cherry (TC) or placebo (PL) supplementation on hypoxic exercise performance. Thirteen healthy participants completed an incremental cycle exercise test to exhaustion (TTE) under two conditions: (i) hypoxia (13% OImprovements in endurance exercise performance, such as time trials under a given distance or time to exhaustion, are important for endurance athletes. It has been reported that tart cherry (TC) might improve endurance exercise performance via the facilitation of oxygen delivery (Hypoxic exposure elevates several biomarkers of oxidative stress such as 8-hydro-2′ deoxyguanosine (8-OHdG) [In this regard, TC could potentially improve hypoxic exercise performance by increasing the Accordingly, it was hypothesized that TC supplementation would improve exercise performance under hypoxia, lower oxidative stress, and increase tissue oxygenation in exercising muscles compared to placebo. Tissue oxygenation and deoxygenation kinetics in exercising vastus lateralis muscles were evaluated by near-infrared spectroscopy (NIRS). 