Introduction
death, NSTEACS, NSTEMI, acute coronary syndrome, disability
EVENTS, UNSTABLE ANGINA, EVENTS, ACUTE CORONARY SYNDROME
Non-ST segment elevation acute coronary syndrome (NSTEACS), which comprises non-ST elevation myocardial infarction (NSTEMI) and unstable angina, is a leading cause of disability, hospital admission, and death, and has major impacts on health economies.The Global Registry of Acute Coronary Events (GRACE) risk score (GRS) is designed to stratify risk in patients with acute coronary syndrome and previous research has found its discriminative performance is superior to other acute coronary syndrome risk scores.In the UK, hospital admission and mortality data are routinely and systematically collected. We used these data to conduct a prospective, pragmatic, cluster randomised clinical trial (UK GRS intervention study—UKGRIS) testing the hypothesis that the GRS increases guideline recommended treatment and decreases clinical events in patients admitted to hospital with suspected NSTEACS.