Construction of Met cycle‐related risk model
REGRESSION
All participants were randomly divided into training and testing sets, with equal numbers of 44 healthy individuals and 151 MMD patients in each set. The data of Met cycle‐related metabolites in training set was used to construct the risk score system by LASSO regression (Figure Construction of Met cycle‐related risk model. A. LASSO deviance profiles; B. LASSO coefficient profiles.Coefficients in LASSO regression model of the Met cycle‐related metabolites.
Levels of risk score between different groups. ns, not significant; ***Based on the median risk score value, the MMD patients in training set were divided into low‐risk and high‐risk groups (Table Baseline characteristics of MMD patients in low and high‐risk groups.

Baseline characteristics of MMD patients according to tertiles of the risk score.

