Principal findings
NSTEACS
EVENTS
In this parallel group, cluster registry based randomised clinical trial of 3050 participants admitted to hospital with suspected NSTEACS in England, the prospective use of the GRS did not improve adherence to guideline recommendations for the management of NSTEACS or reduce fatal or non-fatal cardiovascular events at 12 months compared with standard care. Additionally, baseline adjusted EQ-5D-5L utility at 12 months and the duration of hospital admission within 12 months were similar for GRS and standard care.