Conflict of interest
Financial interests: Tomoki Naoe has received speaker honoraria from Astellas, Otsuka, Nippon-Shinyaku, Pfizer, Bristol-Myers Saquibb and Sysmex. Nahoko Hosono has received honorarium from Abbvie GK. Mizuki Ogura has received honorarium from Nippon Shinyaku, Chugai, and AstraZeneca. Kensuke Usuki has received research funding from Astellas、AbbVie、Ono, Chugai, Bristol-Myers Saquibb, Otsuka, Yakult, Agios, MSD, Aperis, Amgen, Alxion, Incyte, Eisai, Kyowa-Kirin, Sanfi, SymBio, Celgene, Daichi Sankyo, Sumitomo-Dainippon, Nippon Shinyaku, Novartis, Mundi, Janssen, and Takeda, has served on speaker honoraria for Novartis, Astellas, Alexion, Eisai, MSD, Otsuka, Ono, Kyowa-Kirin, Celgene, Daiichi Sankyo, Takeda, Nippon-Shinyaku, PharmaEssentia, Bristol-Myers Squibb, Yakult, Sanofi, Pfizer, Abbvie, and Chugai, and has served on consulting bureaus for Alexion, SymBio, Nippon Shinyaku, Otsuka, Chugai, Sanofi, Takeda, Kyowa-Kirin, Astellas, SOBI, and Alnylam Japan. Hirokazu Nagai has received speaker honoraria from Abbvie GK and Nihon Shinyaku Co. Ltd., and research funding from Nihon Shinyaku Co. Ltd.