Introduction
pulmonary embolism, cancer, DVT, VTE, high-density lipoprotein, MR, trauma
PULMONARY EMBOLISM, DEEP VENOUS THROMBOSIS, VENOUS THROMBOEMBOLISM, CANCER, DISEASE, COMPLICATION, DVT
Venous thromboembolism (VTE) is a complex disease that includes deep venous thrombosis (DVT) and its most dangerous complication, pulmonary embolism (PE)In fact, many factors affect the occurrence and development of VTE. In addition to trauma, cancer and other factors, researchers have found that lipids, such as low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglycerides (TGs), may also affect VTE. A meta-analysis of a case‒control study and a cohort study found that HDL and TGs were significantly associated with venous thrombosisMendelian randomization (MR) can use genetic variation as an instrumental variable (IV) of exposure and strengthen the causal inference of the exposure-outcome relationship by reducing confounding factors