4.1. Population and Study Design
kidney or liver damage, T2D, hypoglycemic
A call was made through social networks to recruit the study population according to the following selection criteria: men and women between 60 and 74 years of age, with a clinical diagnosis of T2D treated with metformin and/or glibenclamide as a hypoglycemic agent, without kidney or liver damage, residents of Mexico City. A total of 213 candidates agreed to participate in the study, of which 124 met the established inclusion criteria and signed the informed consent (After performing the baseline measurements of all the clinical and biochemical parameters, a person outside our research team randomly assigned the 124 participants using the online tool “randomizer.com”, integrating the following 3 study groups: (i) experimental group 1000 mg/day (EG1000), 