Clinical Disease Activity
IBD
DISEASE, REMISSION
After the lifestyle program, PCDAI scores and thereby number of patients in remission decreased significantly. This was mainly declared by a decrease in self-reported bowel symptoms on the PCDAI/PUCAI. Fecal calprotectin decreased, but not compared to the control period, mainly due to relatively large intra-patient fluctuations in the control period. As none of the participants experienced any side effects of training or exacerbation of disease, we think the intervention was safe; our sample size is too small to draw definite conclusions and longer-term effects remain unknown. Whether the decrease in clinical disease activity can be attenuated by our intervention is hard to verify. The only other long-term exercise intervention (8 weeks of exercise gaming) in pediatric IBD patients, also showed a decrease in inflammatory markers (