Depression
suicidality, depression
Transgender and gender-diverse individuals have disproportionately higher rates of depression compared with the general population,The PHQ-9 has been used to assess depression in several analyses. Consistent with our findings, a recent 12-month prospective observational study using the PHQ-9 in transgender and gender-diverse youth reported 60% lower odds of depression and 73% lower odds of suicidality in transgender and gender-diverse youth treated with puberty blockers or GAHT, compared with those who had not yet initiated treatment.