Limitations
LACI
AMI, EVENT
Our study has several limitations. CMR imaging was performed at several study sites using different CMR-vendors. However, all centers followed an identical study protocol and centralized image post-processing was performed in an experienced and blinded core laboratory. It is noteworthy, that an optimal timepoint for CMR imaging in patients following AMI is not known and, therefore, it cannot be excluded that further changes of atrioventricular coupling might occur at later stages after AMI. Due to contraindications and length of an CMR scanning procedure only stable and preselected patients were included in this study, which might lead to a selection bias with a lower event rate. Nevertheless, the study demonstrated significant associations of LACI with MACE which could be even more pronounced in the presence of more MACE.