Co-occurrence of biomarkers
MUTATED
HER2-related biomarkers (HER2-E subtype, high gene ratio, homogeneous staining, high H-score, and IHC3+ status) were all highly correlated with each other, as shown in the balloon plot in Additional file Other markers showing a negative association with high HER2-related biomarkers were hormone receptor-positive status (all with the exception of HER2 H-score), Interestingly, a positive hormone receptor status was more likely to be associated with low immune marker expression and to co-occur with high bcl-2 and high HER3 RNA expression. Mutated 