Conclusion
Pandemic dynamics in Southern Vietnam feature specific variations in incidence, and these largely reflect the success of the substantial, ongoing restrictive measures put in place during the early stages of the pandemic. Tracking of circulating lineages revealed major variants from the list of variants-of-concern, including intragenomic variability within circulating lineages. Further evaluation of epidemiological features and the circulation of SARS-CoV-2 variants is an essential part of COVID-19 surveillance in Vietnam.