Ethics
All procedures were performed in accordance with the Helsinki declaration and its amendments. The study was approved by Institutional Review Boards at I.M. Sechenov First Moscow State Medical University and V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology (Doc. №10–18/11.2018). All participants signed Informed Consent for the study. Study is registered on the clinicaltrials.gov web-site (Clinical trials NCT05455151, 13/07/2022).