Statistics
Statistical analyses were performed using IBM SPSS Statistics version 24 (IBM Corp, Armonk, New York, United States). The presented data were described using mean values ± standard deviation (SD), median [25th–75th percentile], or frequencies and percentages. Differences between the two groups were evaluated using the chi-square test or Fisher's exact tests for categorical variables and unpaired t-tests or Mann–Whitney U tests for continuous variables, depending on the assumption of normality holds. All reported p values are two-sided, and p values of < 0.05 were considered statistically significant.