Conclusions
premenstrual somatic and mental complaints
PMS
Supplementation of γ-Toc 360 mg for 7 days during the luteal phase was suggested to alleviate premenstrual somatic and mental complaints, with the underlying mechanism possibly involving the diuretic effect of γ-CEHC. Additionally, intake of γ-Toc 360 mg was well tolerated and safe in premenopausal women. γ-Toc may be useful as a nutritional supplement for mitigating PMS symptoms and improving women’s quality of life. Therefore, additional trials of longer duration and larger sample size are required to confirm these beneficial effects of γ-Toc.