Ethical approval
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (from Ethical Committee of Azienda Ospedaliera Sant’Andrea on 2019/01/14; from Ethical Committee of Istituto Dermopatico dell’Immacolata on 2017/05/25) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.