Cumulative incidence of first childbirth among female patients aged 18–40 years at enrollment.
Abbreviations: CMT combined-modality treatment, PET-2 positron emission tomography after two cycles of chemotherapy.Within a median follow-up of 62 months after therapy, 37 of 590 male patients aged 18–60 years at enrollment reported to have had children. In 28 (76%) of these patients, sperm cryopreservation had been done before therapy. However, information about whether cryogenic material had been used was not available.