Results
stoma, GI, gastrointestinal.
REGRESSION, PERFORATED DIVERTICULITIS
A total of 222 patients with Hinchey III perforated diverticulitis were included in the pooled analysis, of whom 116 were randomized to the laparoscopic lavage group and 106 to the primary resection group (Study flow chartPRA, primary resection with anastomosis; ITT, intention to treat.Baseline characteristics of all patients with Hinchey III diverticulitisBaseline characteristics for all patients who had laparoscopic lavageBaseline characteristics of all patients who underwent resectionIn the resection group, patients had either Hartmann's operation (67), or sigmoid resection with (15) or without (18) a stoma. Two patients had an anastomosis that was later converted into Hartmann's operation, and four patients in the resection group underwent lavages. The median age of patients in the Hartmann's group was 69 (i.q.r 58–76) years and that of patients undergoing primary anastomosis was 58 (i.q.r 47–69) years.The treatment failure rate was 32.8 per cent (38 patients) in the laparoscopic lavage group and 18.9 per cent (20 patients) in the resection group (In univariable analysis, smoking was a risk factor for treatment failure in the laparoscopic lavage group (OR 3.24, 95 per cent c.i. 1.19 to 8.81; Univariable logistic regression analysis of risk factors for treatment failure with interaction model for adjustment for studyValues in parentheses are 95% confidence intervals. GI, gastrointestinal.In multivariable analysis, the only statistically significant risk factors for treatment failure were smoking (OR 7.05, 2.07 to 23.98; Multivariable logistic regression analysis of risk factors for treatment failure with interaction model for adjustment of studyValues in parentheses are 95% confidence intervals.