Benefits and harms
diarrhoea, bleeding, anaphylaxis, convulsions, impaired colour vision, vomiting, visual disturbances, hypotension, PPH, deaths, dermatitis, trauma
HYPERSENSITIVITY REACTIONS, BLEEDING, ANAPHYLAXIS, ADVERSE EVENTS, DERMATITIS, VENOUS THROMBOSIS
Early tranexamic acid treatment cuts the risk of bleeding deaths in PPH and trauma by a third [Tranexamic acid is widely used and well tolerated. Potential adverse events reported by manufacturers to be associated with the use of tranexamic acid according to frequency are:Common (≥ 1/100 to < 1/10): diarrhoea, vomiting and nauseaUncommon (≥ 1/1000 to < 1/100): dermatitis allergicRare: hypersensitivity reactions including anaphylaxis, convulsions, visual disturbances including impaired colour vision, malaise with hypotension (generally following a too fast intravenous injection) and arterial or venous thrombosis