Pharmacokinetic analysis
BLOOD, LRTI
Blood samples for determination of nirsevimab serum concentrations were collected pre-dose (at screening or Day 1) and 30 (MELODY only), 90 (Phase 2b only), 150, and 360 days post-dose and at the time of a MA LRTI. In MELODY, an additional blood sample was collected 7 days post-dose in Japan, while in Europe, blood was collected 15 instead of 30 days post-dose. Nirsevimab serum concentrations were analyzed as described previously in ref. 