Acknowledgements
ENGELMANN
The team of authors would like to thank Lucas Sandkämper from IMBEI for the useful discussion in the context of the General Data Protection Regulation and Tobias Engelmann from the Interdisciplinary Center Clinical Trials (IZKS), University Medical Center of the Johannes Gutenberg University Mainz for the development and administration of the documentation system and the management of the Trust Centre. They also thank Christian Kampmann from the participating health insurance company and Christoph Leinz from the Statutory Health Insurance Physicians, Rhineland-Palatinate for providing routine data.