Individual fits to the serial qPCR data under the two main Bayesian hierarchical models (pink: linear model with RNase P adjustment; green: nonlinear model with RNase P adjustment).
fits, oropharyngeal virus
APPENDIX
Lines show mean fits; shaded areas show 95% credible intervals around fits. Black circles show viral load measurements for each independent swab. Only follow-up data included in the mITT analysis data set are shown (e.g., for patients who switched medication after day 2, we only show data up until the switch, i.e., the data that were used for the analysis). Site codes: TH1=HTD, TH57=BP, TH58=VJ.Targeted viral genotyping (Appendix 1) indicated that all 10 casirivimab/imdevimab recipients had the SARS CoV-2 Delta variant (B.1.617.1) (All analytical models of oropharyngeal virus clearance were in excellent agreement, giving near identical point estimates and credible intervals (