General characteristics of the study
In total, of the 198 screened volunteers, 46 qualified participants were recruited, among which 45 completed the study with one participant in the placebo group discontinuing the study because of pregnancy (The study flow diagram.Baseline characteristics of the participants.Numerical data are expressed as mean (SD) and categorical variables as number (%).p-value based on the independent samples t-test.p-value based on the chi-square test.