Study design
Heart Failure, HFpEF
HEART FAILURE, DIASTOLIC DYSFUNCTION, HYPERTENSION
Japan Working Group on the Effects of Angiotensin Receptor Blockers Selection (azilsartan vs. candesartan) on Diastolic Function in the Patients Suffering from Heart Failure with Preserved Ejection Fraction: J-TASTE trial was a multicenter, randomized, open-labeled (candesartan vs. azilsartan), and assessor(s)-blinded, active controlled using candesartan, parallel-group clinical trial, to test the hypothesis that azilsartan improves diastolic dysfunction in either HFmrEF or HFpEF patients with hypertension. This trial was first registered with the UMIN-CTR registry (UMIN000022556) on 31/05/2016 before the enrollment and also registered with the Japan Registry of Clinical Trials (jRCTs051180137) on 18/03/2019.