Quality of life and health economic analysis
Cancer
CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY, CANCER
Quality of life and cost-effectiveness of treatment will be assessed at each time point during the study, i.e., at baseline, post-operatively, every 3 months for year 1, every 6 months for years 2 and 3, and annually for years 4 and 5. Quality of life data related to chemotherapy-induced peripheral neuropathy will be collected using the FACT/GOG-Ntx4 subscale. Additional quality of life data will be collected using European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the Colorectal Cancer-Specific Quality of Life Questionnaire (QLQ-CR29) and the EuroQoL 5-Dimension 5-Level (EQ-5D-3L) subscale. A pilot will be undertaken on 40 patients to assess the frequency with which questionnaires are successfully completed, with a view to adapt the frequency and length of the RUtINE™ questionnaire should the response rate be low.