AT THE BEDSIDE
PD, acute renal failure
ACUTE RENAL FAILURE
The NIDUS delivered more precision of ultrafiltration than control (CVVH and PD) and chemical clearances better than PD but less effectively than CVVH.The NIDUS device is clinically effectively, delivering appropriate blood clearances and accurate, controllable fluid removal, with an appropriate safety profile.NIDUS has a potential role in the delivery of RRT to some patients.Critically unwell babies in PICUs may develop acute renal failure and require management with renal replacement therapy (RRT), which is delivered continuously to minimize instability. Their small size and the current limited technology available (which is not licensed in United Kingdom for babies weighing <8 kg) present specific challenges (We undertook the Infant KIdney Dialysis and Utrafiltration (I-KID) study to determine the clinical efficacy, outcomes, and safety profile of a novel non-Conformité Européenne-marked hemodialysis device for infants under 8 kg, the Newcastle Infant Dialysis Ultrafiltration System (NIDUS) (