Author contributions
ADVERSE EFFECTS
FL and SML had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis, including and especially any adverse effects. PF, TW, SH, QW, ZH, LL, WH, FH, PF, JG, HD and GY contributed substantially to the study design, data analysis and interpretation, and the writing of the manuscript.