OM treatment
bone marrow suppression
MUCOSAL ULCERS, REMISSION, DETACHMENT, BONE MARROW SUPPRESSION
As part of the intervention, the patients in the experimental group gargled with IL-11 rinse, which was formulated as follows: 3 mg of IL-11 was added to 100 mL of normal saline, which was then stored at 2–8 °C and dispensed every day. The patients in the control group gargled with a solution of 5% sodium bicarbonate and purified water at a ratio of 1:1. The patients in both groups gargled with their respective solution in the morning, after lunch, after dinner, and half an hour before going to bed for 4 days. Each time, they rinsed with water before gargling and gargled with about 25 mL of solution for 5 min. The intervention began on day 1 of chemotherapy and ended after bone marrow suppression phase remission (detachment of granulocyte deficiency) or after their oral mucosal ulcers had healed.