Statistical analysis
seizure
ADVERSE EVENTS, ADVERSE EFFECTS
The data were coded and analysed with SPSS (version 28.0.1.1 (14)). Continuous variables were analysed with frequency, mean, standard deviation, median, minimum, and maximum. Contingency tables with chi-square test for independence (Pearson’s chi-square and Fisher’s exact test) were used to test group differences between categorical variables (seizure reduction and related factors (≥ 3/< 3 seizure types, GTK, ≥ 3/< 3 ASMs, median weekly seizure frequency, age at start of treatment ≥ 18/< 18, major change in ASMs, and occurrence of adverse effects). Group differences in rAML, seizure reduction, frequency of adverse effects, and grade 3–4 adverse effects between Norway and Denmark were analysed by contingency tables with chi-square test for independence (Pearson’s chi-square and Fisher’s exact test). The Mann–Whitney U test was used to test group differences between continuous not normally distributed variables, occurrence of grade 3–4 adverse events, and group differences between CD/ratio and seizure reduction/rAML reduction. A 