Statistics
In our previous study (ESO-Shanghai 8), the 2-year local control rate was 69.4% in the preliminary results when design of this study in September, 2016. Our hypothesis was the 2-year local control rate was over 83% with the elevated radiotherapy dose and the addition of concurrent chemotherapy. A total of 70 patients were needed to test this hypothesis with a one-sided type I error of 5%, a power of 80%, and a dropout rate of 10%.Survival was estimated with Kaplan–Meier method. Log-rank test was used to compare the survival and Pearson’s χA 