Statistical analyses
OSF
POSITIVE
The study was powered to replicate our previous finding that adolescents experienced a weaker psychotomimetic effect of cannabis than adults [The analysis followed our OSF analysis plan [
Secondary outcome variables were primarily analysed via two‐way or three‐way mixed ANOVAs similar to the ANOVAs described above. Three‐way ANOVAs included a within‐subject factor of time. For subjective effect VASs, time had levels: T1/T2 to T5, and separately area‐under‐the‐curve and peak effects were analysed. For prose recall, time had levels: immediate and delayed. For THC and CBD plasma results at T2, mixed effects models were performed to account for eight missing data points out of 144. Positive and negative PANSS scores were analysed using mixed ANOVAs and supported with generalised estimating equations models and χ