CONCLUSION
aMCI
In this study, we identified significant alterations in radiomic features related to aMCI within the frontal lobe white matter. These alterations demonstrated the ability to discriminate aMCI from NC with a relatively high diagnostic efficacy as evidenced by an AUC of 0.82. The calibration curve of the radiomics model indicated that the predictions align well with an ideal model. Furthermore, DCA illustrated a high net benefit achieved by the radiomics model. In conclusion, the radiomics features of the 3D‐T1 frontal lobe white matter may serve as a surrogate imaging marker to aid clinicians in screening for aMCI.