Study design
The Malaysian Soy and Mammographic Density (MiSo) StudyCONSORT flow diagram from enrolment to completion of the MiSo Study. Drop-out participants include those who were lost to follow-up or discontinued the intervention. Women were considered ‘adherent’ if they had an intervention compliance of more than 80 %. ‘Non-adherent’ participants had an intervention compliance of less than 80 %.This study was conducted according to the guidelines laid down in the Declaration of Helsinki and all procedures involving research study participants were approved by the Ramsay Sime Darby Healthcare Independent Ethics Committee (Reference #: 201805.1, 12 July 2018) and the University Malaya Medical Centre Medical Research (Reference #: 202043-8441, 22 April 2020). The study is also registered on clinicaltrials.gov (Reference #: NCT03686098). Written informed consent was obtained from all participants of the study.