Trajectories over time in people not receiving the trial treatment
DECAY
Trajectories for the “Steady decline”: “Early decline”:“Late decline”: “Intermediate decline”:Note that the non-linearity enters only in the fixed part of the model – the time component of the random effects, Values of parameters were chosen such that all mean trajectories start from 6 at Mean trajectories over time in participants not receiving the trial treatment (left-hand panel); spaghetti plots for 20 people not on the trial treatment, with a residual error of Parameter values used for the (co-)variances are: In a second version of the intermediate decline trajectories, a person-level effect was added to the function for time so that the time of the steep decay of the trajectory occurs at different times for each person. Details are given in section A1 of the 