The change in microbiome composition is associated with the change in metabolites
We next asked whether the changes observed in the gut microbiome and serum metabolites are associated with each other, independent of their significant level of change, nor their found mediatory role. Since we did not have enough samples to train our own model, we utilized a model previously trained to predict serum metabolites from gut microbiome species composition in a single time point observational cohort of healthy adults, to predict the change in metabolites in our interventionary cohort