Ethics approval and consent to participate
Damas
All participants gave written informed consent. The study was conducted based on the Declaration of Helsinki and was approved by the Institutional Review Boards of the University of South Florida (Tampa, FL; Pro00020044, approved August 30, 2018), Ponce Health Sciences University (Ponce, PR; 170807-BS, approved December 6, 2017) and the Comité de Seguimiento de la Investigación Clínica at Hospital Damas (HD 19-17, approved December 18, 2017).