Discussion
TGF-β1, inflammation, fibrosis, intrauterine inflammation, infection, IUA, endometrial basal layer damage
ENDOMETRITIS, INTRAUTERINE ADHESION, INFLAMMATION, FIBROSIS, INFECTION
Finally, 10 vaginal secretion samples were selected in the group C, I, E and L, a total of 40 samples were used for high-throughput sequencing. In α-diversity, there are significant differences in Shannon (P < 0.01) and Simpson (P < 0.005) (Fig. 
The effect of  We allow visitors to reproduce images with permission and/or creditA combination of TCRA supplemented with IUD [Nowadays, the antagonistic and synergistic effects between vaginal microbiota are significant in keeping the female reproductive system in good condition [It is well known that the constant stimulation of infection and inflammation impairs the repair of endometrial basal layer damage, leading to intrauterine inflammation and fibrosis, and ultimately to IUA [The purpose of IUA treatment is to reduce endometrial fibrosis and boost endometrial regeneration. TGF-β1 and MMP-9 are two profibrotic and antifibrotic cytokines whose interactions control the damaged endometrial healing process [In high-throughput sequencing results, the composition and diversity of vaginal microflora in mice with IUA were significantly changed, as shown by PCoA in Fig. In the clinical investigation, 27.08% of patients with IUA had endometritis, which were positive for CD38 and CD138, which was consistent with previous studies on the etiology of intrauterine adhesion [After TCRA, by comparing with estrogen, we found that the effect of estrogen in promoting endometrial growth is better than that of Although This study confirmed that the supplementation of 