Participants
vitiligo, allergy, photodermatoses
VITILIGO, ALLERGY, RECRUITMENT, OF SKIN CANCER, PHOTOSENSITIVITY
This study was conducted at the Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. Thai patients aged 10 years or older with stable vitiligo and had at least three similarly sized lesions in the same anatomical area were prospectively enrolled in to the study. Patient recruitment process was performed at dermatology outpatient clinic, vitiligo clinic and phototherapy clinic. All patients had stable vitiligo which defined as no new lesion and no clinical signs of active vitiligo (confetti repigmentation, trichrome lesion, Köebner phenomenon, or inflammatory lesion) within 3 months. The recruited participants had to wash out topical corticosteroids and/or calcineurin inhibitors for 2 weeks, and had to discontinue phototherapy for 4 weeks before starting the study. Patients who were pregnant or lactating, or who had a history of skin cancer, allergy to PGF2α analogues, photosensitivity, or photodermatoses were excluded. Participants who could not follow the study protocol or who received phototherapy more than twice a week were withdrawn from the study.