Introduction
HSP, Lokomat, neurodegenerative
disorders
HEREDITARY SPASTIC PARAPLEGIA, HSP, DEGENERATION
Hereditary spastic paraplegia (HSP) is a heterogenous group of neurodegenerative
disorders. It is caused by retrograde axonal degeneration of the corticospinal
tract, posterior spinal columns, and spinocerebellar fibers.Previous uncontrolled studies with pre-post assessments reported beneficial effects
on balance and/or gait performance following task-specific gait training in people
with HSP. The interventions consisted of 18 sessions of robotic Lokomat training
(n = 13),So far, the potential effectiveness of gait-adaptability training has not been
studied in people with HSP. Therefore, we designed and conducted the Move-HSP
trial