Measures
depression, Depression, respiratory distress, trauma
CONGENITAL CONDITIONS, SECONDARY
Assessments included surveys, laboratory viral load testing, pharmacy data, and data abstracted from medical charts and a Depression Care Registry maintained by peer mothers and nurses. Survey measures were interviewer-administered; those that had not been translated into Luganda, the local language, during our prior research were translated using standard translation and back-translation methods.Response to depression treatment is the focus of this analysis. At baseline and two months post-pregnancy completion, the PHQ-9, which has been used successfully in rural Uganda (Nakku, et al., Survey measures included sociodemographic characteristics (age and any secondary education); pregnancy-related characteristics (gestation length, pregnancy outcome, whether pregnancy was planned); health functioning and quality of life; depression treatment-related factors (PHQ-9 at treatment initiation, weeks on treatment); relationship factors (e.g., relationship status, partner knowledge of patient’s HIV status, partner support and involvement in the pregnancy; and experience with interpersonal violence [IPV]); experience of trauma (childhood or recent); PMTCT knowledge and attitudes; and problem solving orientation (positive, negative, or avoidant). Surveys also asked about any ADT side effects, degree to which they interfered with daily life, and infant signs of poor neonatal adaptation (i.e., jitteriness, respiratory distress). Mothers were asked if they sought medical care for these signs.Data related to HIV diagnosis and care (e.g., time since diagnosis, whether ART was started during current pregnancy) and whether the infant had any serious congenital conditions were abstracted from the patient’s clinical chart. An HIV viral load assay was collected at baseline and two months post-pregnancy completion, and percent of prescribed ART pills taken was calculated using pharmacy refill data.The Online Supplement provides additional detail on these measures.