Gene expression profiling and analyses
tumor
DISEASE PROGRESSION, TUMOR
RNA was extracted from FFPE pretreatment tumor biopsies available from 38 patients and analyzed retrospectively on the NanoString nCounter system. For ten patients, there were also tumor biopsy specimens available at the time of disease progression, allowing for an examination of gene expression changes before and after treatment in matched patient samples.The geometric mean of canonical marker genes was used to compute scores for immune cell types