Missing data
TB
Our sample size calculations have adjusted for potential refusals or losses to follow-up, and thus we expect to achieve the same level of power if up to 20% of diagnosed TB patients either refuse to participate or are enrolled and do not complete the study. We anticipate that these losses will occur completely at random and thus inference based on remaining participants will be valid. Data will be abstracted from clinic records, and we expect some missing data. We will work with study staff to investigate any missing data related to study endpoints to determine if there is systematic missingness. If appropriate, suitable imputation methods will be applied for missing covariate data.