Training Data Set
pleural thickening
PLEURAL THICKENING, AORTIC ARTERIOSCLEROSIS
In the training data set, 40 743 of 74 082 (55.0%) cases were abnormal and 33 339 (45.0%) were normal. The abnormal cases included 10 706 (14.5%) with 1 abnormal sign and 30 037 (40.5%) with more than 1 abnormal sign. Among the 23 abnormal signs, thickened bronchovascular markings (37 954 [51.2%]) was the most common, followed by pleural thickening (12 789 [17.3%]), nodule (12 192 [16.5%]), consolidation (9701 [13.1%]), and aortic arteriosclerosis (6837 [9.2%]).The CNN showed high performance in classifying the 23 abnormal signs. The mean (SD) AUC of these abnormal signs was 0.96 (0.03), ranging from 0.88 (95% CI, 0.87-0.89) to 1.00. The mean (SD) accuracy was 0.95 (0.06); sensitivity, 0.60 (0.25); specificity, 0.96 (0.08); and F1 score, 0.70 (0.20). High AUC values were noted for common abnormal signs, namely, pleural thickening (0.95; 95% CI, 0.94-0.96), nodule (0.88; 95% CI, 0.87-0.89), consolidation (0.94; 95% CI, 0.93-0.95), and aortic arteriosclerosis (0.97; 95% CI, 0.96-0.98).