Implant procedure
allergies, pain
ALLERGIES
P-MSCs were administered under spinal anesthesia (3 patients) or IV sedation (6 patients) to relieve pain. P-MSC treatment was administered at two time points, eight weeks apart. The total amount of the suspension was injected intramuscularly using a 30 G needle to a depth of 1–1.5 cm and an area of 10 × 6 cm (30–40 sites with 0.5–1.0 ml of P-MSCs per site) on each occasion. The injections were distributed as follows: the knee to the ankle was divided into five equal parts in four lines (the anterior, anterolateral, and superficial posterior compartments of the leg), and six points were identified at the dorsum of the foot, and the surroundings of the wound (if there was a wound).Patients received 100 mg hydrocortisone before injection to avoid side effects such as allergies. Oxygen saturation was measured 30 min before and 6 h after the injection of P-MSCs throughout the dosage.