1. Introduction
gastrointestinal symptoms, gastrointestinal motility
HYPERSENSITIVITY, FUNCTIONAL GASTROINTESTINAL DISORDER, DISORDERS
Background: Aversive conditioning weakens the gratifying value of a comfort meal. The aim was to determine the effect of a cognitive intervention to reverse aversive conditioning and restore hedonic postprandial response. Methods: This was a randomized, sham-controlled, single-blind, parallel study that was conducted on 12 healthy women (Ingestion of a meal induces sensations that persist during the postprandial period in parallel to digestion, and these sensations are key to ingestive behaviour [We hypothesized that acquired food aversion may be reversed using deconditioning. In this context, the term deconditioning refers to reversal of previously conditioned behaviours, i.e., unlearning aversive conditioning [Functional gastrointestinal disorders, the most prevalent diagnoses in gastroenterology, represent a spectrum of conditions characterized by altered interaction between the gut and the brain. This group of disorders is distinguished by gastrointestinal symptoms related to various potential mechanisms, including disturbances in gastrointestinal motility, heightened visceral sensitivity (i.e., visceral hypersensitivity), altered mucosal and immune functions, alterations in gut microbiota, and modifications in central nervous system (CNS) processing of gut-derived stimuli [