What Are the Clinical Implications?
death, myocardial scarring, ventricular arrhythmias, ischemia, left ventricular systolic dysfunction, ischemic left ventricular dysfunction
SUDDEN CARDIAC DEATH, ISCHEMIA, LEFT VENTRICULAR SYSTOLIC DYSFUNCTION, VENTRICULAR ARRHYTHMIA
Patients with ischemic left ventricular dysfunction should not undergo percutaneous coronary intervention with the sole aim of preventing the occurrence of ventricular arrhythmias.In stable patients who are treated with guideline-directed medical therapy and meet criteria for implantable cardioverter defibrillator implantation, there is no evidence to support delaying implantation merely to assess the effect of percutaneous coronary intervention because the latter was not found to improve left ventricular function.Ischemic left ventricular systolic dysfunction is associated with significant morbidity and mortality. The leading cause of death in this population is sudden cardiac death, resulting largely from ventricular arrhythmias.The generation of ventricular arrhythmias in this population is believed to relate to both myocardial scarring and inducible ischemia.