Strengths and limitations
This is the first study, to the authors’ knowledge, to focus on treatment burden in PEH, adding knowledge about a marginalised patient group. It used a previously validated measure of treatment burden, the PETS, which was interviewer-administered in person to ensure understanding and reduce the number of missing responses. However, the study participants were restricted to one country (Scotland) and most participants were White males, so findings are not necessarily generalisable across different marginalised populations. The current study did not include input from PEH when tailoring the PETS for administration in this population, which is a limitation. Although the amount of missing domain scores was not significant, any missing data have the potential to skew scores.