Background
organ failure, death, trauma
ACUTE PANCREATITIS, ACUTE PANCREATITIS
Acute pancreatitis may develop under a severe form comprising persistent organ failure and requiring admission to the intensive care unit [Epidural analgesia is widely used for analgesia during labor or major surgery, and after surgery or trauma in some intensive care unit patients [Based on the hypothesis that epidural analgesia could influence clinical outcome, we conducted the multicenter EPIPAN (epidural analgesia for acute pancreatitis) trial to determine whether thoracic epidural analgesia combined with usual care would result in more ventilator-free days than usual care alone in intensive care unit adults with acute pancreatitis, considering ventilator-free days as an endpoint that reflects the need for intubation and the duration of invasive mechanical ventilation when needed, while accounting for death as a competing risk [