Introduction
cognitive impairment, MCI, dementia, declines in cognition compared, Alzheimer’s disease, depression, cognitive decline, AD
Corresponding Author: Y.-I. ShinClinical and Translational Impact Statement—The HB-CCT may be a positive tool for cognitive functioning improvement in community-dwelling adults with MCI.Objective: There is a growing importance for the home-based (HB) support services, and computerized cognitive training (CCT) has been reported as an effective intervention for cognitive impairment. However, there is still a need for further verification of the effect of HB-CCT. This study aimed to determine the effectiveness of HB-CCT on the cognitive function of community-dwelling adults with mild cognitive impairment (MCI) as well as safety in its use. Methods: Fifty community-dwelling adults with MCI were included, of which 25 each were randomized to either HB-CCT or control groups. Evaluations of comprehensive cognition, memory, attention, language, executive function, and depression were performed before and after the intervention, including three times a week for eight weeks in the intervention group and eight weeks apart with no intervention in the control group. Results: In baseline and post-evaluation comparisons, the HB-CCT group showed significant improvements, while the control group did not show significant changes. Statistically significant variations were noted between the HB-CCT and control groups in all post-intervention evaluations relative to baseline. Additionally, no side effects were observed. Conclusion: Beneficial effects on cognition and depression were noted in the intervention group compared with the control group, suggesting that HB-CCT may be a positive tool for cognitive improvement in adults with MCI.The development of medical technology has increased life expectancy; however, cognitive decline remains an issue, as the number of older adults with Alzheimer’s disease (AD) or dementia continues to increase with aging populations Mild cognitive impairment (MCI), an early stage of dementia, is defined as significant declines in cognition compared with individuals of the same age and similar educational levels Various studies on the prevention of cognitive decline have been conducted Representative CCTs, including CogReHab, COMCOG, Captain’s Log, Rehab.com, and Cog-med, are mainly used in hospitals, which may limit patient accessibility 