2.2. Follow-Up
BrICS-LIT, tumor
PATHOLOGY, TUMOR, BRAIN TUMOR
After patients completed RT, they returned for follow-up imaging every 2–3 months. At University of Miami and Emory University, follow-up occurred every 2 months, while patients at Johns Hopkins University had follow-up visits at 3-month intervals. Standard clinical follow-up was performed using the institution standard brain tumor protocol. T2 FLAIR and T1w-CE MRIs from each follow-up visit were uploaded to BrICS-LIT [In Often, if an enhancing lesion grows suspiciously fast, patients will undergo additional surgeries during this follow-up period. Many patients on this trial had second or even third surgeries to remove an enhancing lesion that was suspicious for tumor. After those surgeries, clinical pathologists at each respective site assessed tissue samples for presence of tumor and reported findings in pathology reports.