Trial design
The PROSECCO study was a multicenter noninferiority randomized controlled trial. The study was performed in 14 university and teaching hospitals in the Netherlands, collaborating in the Dutch Consortium for Healthcare Evaluation and Research in Obstetrics and Gynecology, between 2016 and 2021. The study was registered prospectively in the Dutch Trial Register (NTR 5357; registration date: 11 August 2015). The full study protocol was published in 2019 [