Change from baseline in individual symptoms and categorical responder analysis
TSS
Descriptive analyses of the individual MPN‐SAF TSS items include the absolute proportion of patients assigned to each response category at baseline and at Week 24 based on the average of their reported scores (none: 0 points; mild: 1–3 points; moderate: 4–6 points; severe: 7–9 points; very severe: 10 points). Missing responses were not included in the denominator reporting proportions of responses.The proportion of patients experiencing change (e.g., improved, stable, declined/worsened) was also reported at Week 24. “Declined/worsened” was defined as an increase of at least two points, “stable” as a change of at most one point, and “improved” as a decrease of at least two points.