3.4.8. Incidence of Adverse Effects of Ivabradine
FLASHING LIGHTS, PHOSPHENES
The use of ivabradine was safe and well-tolerated. No patient had to stop treatment with ivabradine. An ECG was recorded for every patient at every visit, and no significant changes in PQ, QRS, or QTc intervals were detected. However, three patients reported visual side effects (phosphenes). All three patients reported Grade 1 visual side effects: 1–2 recurrent low-intensity flashing lights in their eyes, which did not interfere with their activities of daily living and resolved spontaneously after a few days. 