Conclusion
BREAST CANCER
In a series of trials investigating de-escalation of the surgical management of the axilla, the TAXIS trial so far stands out in including cN + patients both after NST as well as in the upfront surgery setting, thereby investigating axillary surgery de-escalation at the far-end of the risk spectrum of node-positive BC patients. The radical Halstedian approach has gradually evolved to an enhanced, oncologically safe, and less-invasive surgery, with TAXIS investigating a novel concept for clinically node positive breast cancer.