2.7.5. Metabolic pathway analysis (MetPA).
Metabolic pathway analysis database identified possible biodisturbed metabolic pathways through metabolic pathway concentration and topological analysis. It also analyzed the relevant metabolic pathways of different metabolites in the 3 groups with the hypergeometric test data analysis algorithm and Relative-Betweenness Centrality topology structure. Based on the relative response values of metabolites identified in the metabolic pathways and the dimensionality reduction algorithm, the relative response values of the metabolic pathways were obtained. The correlation coefficients between the metabolic pathways were calculated to draw the metabolic pathway association network diagram.