Conclusions
stroke
INTRACRANIAL BLEEDING, STROKE, SECONDARY
In this secondary analysis of a randomized clinical trial of older adults, there was no statistically significant benefit from aspirin in preventing stroke or any conventional stroke etiological subtype. However, aspirin significantly increased the overall risk of intracranial bleeding. These data support the recommendation of the USPSTF that low-dose aspirin should not be prescribed for primary prevention in healthy older adults.