Authors’ contributions
SE, KPD, HHM
HHM
MMH and YCM formulated the research question, and designed the study. MHB authored the first draft of the manuscript. YHH devised the data analysis plan. MHB, TS, AB, and CP oversaw the collection of clinical data. MMH, YCM, RER, YHH, SE, HHM, PRC, BE, NGJ, KPD, DD, and RJM contributed to study design. MMH, YCM, AM, and ZD provided general oversight of the study. YCM provided general oversight of this work. All authors reviewed this manuscript, provided feedback, and approved the manuscript in its final form.