Research objective and hypothesis
psychosis
SECONDARY
The aim of this registered research (ClinicalTrials.gov; registration number NCT04764708; registration day 21/02/2021) was to preliminarily explore the effectiveness of a novel integrative recovery-oriented form of psychotherapy specifically tailored to clinical manifestations of SPD (i.e. ESTS). Thus, we pilot-tested through a parallel double-blinded RCT on repeated measures the non-inferiority between the experimental treatment and a combination of cognitive behavioral therapy (CBT) for PDs [Recruited patients were allocated on a 1:1 ratio between the two arms. Our hypothesis was that the experimental treatment without medication would show effectiveness at least equal to a presumably effective treatment that integrated CBT and psychopharmacological interventions (registered primary and secondary outcomes are described in Methods). This hypothesis is consistent with studies that report how interventions tailored on the specific clinical manifestations of psychosis can be as feasible as a combination of psychosocial and psychopharmacological interventions [