6. Conclusions
Ingestion of a liposomal MVM supplement differentially affects the concentrations of some vitamins and minerals appearing in the blood, volume distribution, clearance rates, and elimination from the blood compared to a non-liposomal MVM supplement. These findings are important because they are the first to demonstrate that coating a MVM supplement with liposomes can affect the PK profile of several vitamins and minerals within the MVM supplement and thereby influence nutrient bioavailability. With additional research, this may serve as a more efficient way to deliver vitamins and minerals in dietary supplements. However, additional research is needed to determine the impact of coating a MVM supplement with liposomes on tissue uptake, metabolic function, and health. Additionally, it would be interesting to determine whether ingesting individually coated vitamins and minerals with liposomes within a MVM supplement rather than coating the outside of a MVM supplement may yield differential effects on vitamin and mineral bioavailability. Nevertheless, the present findings support contentions that surrounding a MVM supplement with liposomes affects the bioavailability of individual nutrients contained in the MVM supplement.