Outcomes measures
low/moderate disability, moderate/slight dependence, disability, ARDS
SECONDARY, ARDS
The primary endpoint was disability at day 180, which was evaluated using the BI. The secondary endpoints included changes in the BI on days 28, 90, and 180 stratified by the etiology of ARDS (COVID-19 vs. non-COVID) and overall mortality at day 180. High disability was defined by a BI of 0–60 (total and severe dependency), and low/moderate disability by a BI of 61–100 (moderate/slight dependence and independence). Secondary endpoints included changes in the BI on days 28, 90, and 180 stratified by the etiology of ARDS (COVID-19 vs. non-COVID-19), change in SOFA score within 15 days follow-up and day 180 overall mortality.