Introduction
hypoxaemic respiratory failure, respiratory failure, AHRF, ARDS
RESPIRATORY FAILURE, HYPOXAEMIC RESPIRATORY FAILURE, RESPIRATORY DISTRESS SYNDROME, ARDS
Acute hypoxaemic respiratory failure (AHRF) is one of the most frequent indications for admission to the intensive care unit (ICU), and is associated with hospital inpatient mortality rates of approximately 40%.Acute respiratory distress syndrome (ARDS) is a common cause of AHRF, and survivors of ARDS have a significant and persistent functional limitation up to 5 years after discharge from the ICU, with over 50% of patients not returning to work.The short-term and long-term outcomes from AHRF emphasise the importance of continuing to identify novel therapies that may improve these. The protective ventilation with veno-venous lung assist in respiratory failure (REST) trial evaluated the use of veno-venous extracorporeal carbon dioxide removal (vv-ECCO