Adjudication of Prostate Safety End Points
High-grade prostate cancer, prostate cancer, prostate, Prostate
PROSTATE, BPH, PROSTATE, PATHOLOGY, PROSTATE CANCER
A blinded Prostate Adjudication Committee adjudicated prostate cancer diagnosis and Gleason score, acute urinary retention, and invasive prostate surgical procedure for BPH. The diagnosis of prostate cancer was based on evaluation of tissue from prostate biopsy specimens and surgical procedures by the Prostate Adjudication Center at the University of Colorado. If tissue or slides were not available, the Prostate Adjudication Committee reviewed site pathology reports. High-grade prostate cancer was defined as a Gleason score of 4 + 3 or higher.