Ranking the individual immune markers based on CoR and CoP criteria
We next systematically compared the immune correlates performance of all five antibody markers at D57 and then repeated this comparison for the five markers at D29. We then conducted the ranking combining all markers and both time points, and, lastly, we compared performance of each antibody marker at D29 versus at D57. We ranked by three categories of correlate-quality criteria: (1) risk prediction or strength of association of an immune marker with COVID-19 in vaccine recipients [four criteria: (i) point estimate of hazard ratio per SD increment, (ii) For the D57 markers, PsV-nAb IDWhen ranking performance across all assay readouts and across both the D57 and D29 time points, D29 spike IgG, D29 PsV-nAb ID