Baseline demographics
AORTIC REGURGITATION
The 159 included PEARS patients were operated at 20 centres between 2004 and 2019, while the 142 patients undergoing VSRR from the AVIATOR underwent surgery at 13 centres between 1996 and 2021. Eighty patients in each cohort were matched using a PS analysis. Before matching, patients undergoing VSRR were significantly older, more likely to have mild AR or a history of cardiac surgery, had a higher EuroSCORE II and larger aortic root. After matching, covariates were balanced (Demographics for the total population and matched populationUnderlying aetiology was not used to match. Continuous variables were compared using Mann-Whitney U test, categorical variables via ΧSMD was used to evaluate balance between groups.AR, aortic regurgitation; LVEF, left ventricular ejection fraction; PEARS, personalised external aortic root support; SMD, standardised mean difference; VSRR, valve-sparing root replacement.