Introduction
nausea and vomiting, pruritus, urinary retention, pain
ADVERSE EFFECTS, RESPIRATORY DEPRESSION
Arthroscopic shoulder surgery is acommon orthopedic procedure performed to treat different shoulder pathologies. Due to the significant advancements in arthroscopic techniques, arthroscopic shoulder surgery is being characterized as a “minimally invasive” procedure[Postoperative pain after arthroscopic shoulder surgery has been managed with the use of patient-controlled intravenous analgesia (PCIA), but the opioids most frequently used in PCIA are associated with adverse effects such as nausea and vomiting, respiratory depression, pruritus, urinary retention, and constipation[The brachial plexus provides sensory and motor innervations for the entire upper extremity. Therefore, the interscalene brachial plexus block (IBPB) can provide superior analgesic efficacy and be considered as the gold standard for pain management after arthroscopic shoulder surgery[Dexmedetomidine, a highly selective and potent α2-adrenoceptor agonist, has shown sedative, anxiolytic, analgesic, anti-hypertensive, and sympatholytic properties[