Predictive biomarkers
tumor
TUMOR
In each subgroup categorized by the baseline biomarker levels, PFS was compared between S + XP and XP alone (Figure Predictive biomarker analysis with tumor tissues and circulating soluble proteins. In each subgroup categorized by the baseline biomarker levels, PFS was compared between S + XP and XP alone. In cases of a high (above median) pERK H‐score or VEGF H‐score in the tumor tissue at baseline, patients treated with S + XP had significantly better PFS than those with XP (for high pERK, 6.2 months vs. 4.5 months, HR = 0.53, 95% CI 0.31–0.91, 