Discussion
postoperative pain, swelling, Postoperative pain, pain, inferior alveolar nerve paraesthesia
ADVERSE EVENTS, GASTROINTESTINAL BLEEDING, HAND SWELLING
The aim of this study was to evaluate the effectiveness of preventive IV dexketoprofen on postoperative swelling and pain in patients after orthognathic surgery. In recent years, significant advances in anesthesia techniques have emerged to reduce postoperative pain. Bimaxillary surgery which includes BSSO and LF I osteotomy is well documented orthognathic surgical procedure. Postoperative pain, swelling, inferior alveolar nerve paraesthesia, difference between patient expectations and operation outcome, and postoperative speech problems were shown as sign of low satisfaction after orthognathic surgery (Many systemic agents were used preoperatively to provide adequate analgesia in orthognathic surgery. Naproxen, diclofenac, tramadol, pregabalin, rofecoxib, ondansetron and clonidine are among the drugs used for this purpose(The application of preventive analgesic may start days prior to surgery or just before surgical stimulation (It is known that determination of analgesic consumption with PCA is a good indicator in the evaluation of postoperative pain (The most common side effects after NSAID use occur on the gastrointestinal tract. It is reported that dexketoprofen has low-to-moderate risk in terms of gastrointestinal bleeding. In this study, no adverse events were observed related to dexketoprofen use in any patient.Three-dimensional imaging, such as 3D computed tomography (CT) (Precious Although there are many studies on the analgesic efficacy of dexketoprofen, studies on anti-inflammatory efficacy are limited. Jimenez The strength of this study is that randomized, clinical and prospective study with objective assessment of pain and swelling, standardization of operation related variables and postoperative care. The limitations of study are absence of comparison with other nonsteroidal agents or without using with combination of local anaesthetics and opioids.It has been known that the main complaints of the patients after orthognathic surgery are pain and swelling. Currently, there are no fully accepted or approved postoperative analgesia protocols to provide analgesia after orthognathic surgery. For this reason, the concept of “Multimodal Analgesia" is gaining more importance recently. Preventive single dose of iv dexketoprofen administration is an effective and safe method for the management of postoperative pain in patients undergoing double jaw surgery. Future studies are needed to investigate the preemptive effects of different analgesics with larger sample size.Authors contributions All of the authors contributed on the hypothesis, design, intervention and writing of this study.Ethics Ethical approval for this study was obtained from the Erciyes University Human Research Ethics Committee. Judgement’s reference number: 2018/109.Conflicts of interest The authors declare that there are no conflicts of interest in regard to this work.Funding This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.