Why was this study done?
YFV, yellow fever, TBEV
VIRUS, JAPANESE ENCEPHALITIS, TICK-BORNE ENCEPHALITIS, YELLOW FEVER, FLAVIVIRUS INFECTION
Flavivirus infections pose a significant global health burden, underscoring the need for the development of safe and effective vaccination strategiesCo-administration of different vaccines, including flavivirus vaccines, saves time and visits to health care units and vaccine clinics. It serves to provide protection against multiple pathogens in a shorter time-span; e.g., for individuals travelling to different endemic areasSafety and immunogenicity-related responses have not been appropriately evaluated upon co-administration of many vaccines including currently used flavivirus vaccines, such as yellow fever virus (YFV), tick-borne encephalitis virus (TBEV), and Japanese encephalitis virus (JE) virus vaccinesBecause of this, we performed an open label, non-randomized clinical trial studying the safety and immunogenicity following co-administration of YFV vaccine with TBEV and JEV vaccines