2.12. Statistical Methods for Primary and Secondary Outcomes
Baseline characteristics are presented according to the treatment groups. Categorical variables were presented as the number of counts and proportion of the group. Continuous variables are described as mean and standard deviation or median with interquartile range. Continuous variables were tested against the normality of distribution using the Shapiro–Wilk test and verified with skewness and kurtosis. In the justified cases, a visual assessment was performed. The equality of variance between groups was tested using Levene’s test. For continuous variables distributed normally with homogenous variances, the Student’s 