Outcome measures
SECONDARY
Clinical and radiographic parameters were obtained four weeks after (S2) Phase 1 therapy was completed (baseline) and six months after surgery. The primary outcome was the evaluation of clinical attachment level (CAL), defect base fill (DBF), crestal bone level (CBL), and defect width (DW). The secondary outcomes were to evaluate the soft tissue parameters and BMP-2 level.Radiographic evaluation: Quantitative radiometric and geometric analysis of alveolar bone changes was performed pre-operatively and six months following treatment using cone beam computed tomography (CBCT). For each defect, three measurements were taken: a- DBF, the linear distance from the cement-enamel junction (CEJ) to the base of intrabony defect (CEJ-BD) (
