Introduction
SPONTANEOUS ABORTION, FOLATE DEFICIENCY
One-carbon (1C) metabolism is a complex network of biochemical reactions that activates and transfers methyl groups. This network consists of folate, choline and methionine. The folate cycle produces nucleic acids that are used for DNA and RNA synthesisThe roles of vitamins B2, B6 and B12, folate and choline in one-carbon metabolism. BHMT, betaine-homocysteine Inadequate intake of 1C nutrients is associated with metabolic perturbations at various stages of life. The consequences of folate deficiency during pregnancy on spontaneous abortion and neural tube defects have been well studiedSurveys of dietary intake of 1C nutrients have been concentrated in Western countries, whereas studies in Asia and Africa are limited, and results varied. Mean folate intake levels in countries without mandatory B vitamin fortification varied from 170 μg dietary folate equivalence (DFE)/d in Ethiopia to 246 and 499 μg DFE/d in Sweden and Korea, respectivelyAmong the 1C nutrients, choline is a nutrient of concern for underconsumptionThe objective of the present study is to assess usual intake of 1C nutrients in young Thai adults. A cross-sectional survey was conducted on a sample of healthy Thai university students (