Meaning
OESOPHAGEAL SQUAMOUS CELL CARCINOMA
These findings suggest that oral S-1 chemotherapy with SIB-RT should be considered as an alternative treatment option for patients aged 70 years and older with inoperable EC to improve survival outcomes with acceptable treatment-related toxic effects.This randomized clinical trial compares the efficacy and safety of simultaneous integrated boost radiotherapy with concurrent and consolidated oral S-1 chemotherapy vs radiotherapy alone for patients aged 70 years and older with inoperable esophageal squamous cell carcinoma.