Statistical analysis
Shapiro-Wilk test was used for investigating the normality of age, blood pressure anthropometry variables (height, weight, BMI, and abdominal circumference), duration of DE symptoms, and DE variables (DESS, OSDI questionnaire, TBUT, and Schirmer’s test). All previously mentioned variables were normally distributed, so parametric tests were used for analysis.Because of the non-normal distribution, a non-parametric test was used for OGS analysis. An unpaired Two-way MANOVA was employed to illustrate the difference between time (pre and post) and treatments (DE groups). To measure the size of the difference between DE groups, a partial eta square (