Ethics approval and consent to participate
MINOR
All study procedures were conducted in accordance with the Declarations of Helsinki guidelines and approved by institutional review boards at Seattle Children’s Hospital and Children’s National Hospital. For clinic screening, families reviewed a letter explaining the nature of the larger RCT study and have the option to opt in or opt out of completing the screening forms at their local primary care clinics. All participants above 16 years of age, and from legal guardians or parents of minor participants, and stakeholder members provided informed consent prior to participation.