RANDOMIZATION AND ALLOCATION CONCEALMENT
Each of the 145 quadrants was randomized evenly to the 2, 4, 6, or 8-week reactivation intervals, using the combined CHOOSE and RAND functions in Microsoft Office Excel Mac (v. 16.24; Microsoft, Redmond, USA). The additional quadrant was in the four-week group. The computer-generated allocation sequence was held by the principal investigator, and the clinician was informed of the allocation at the time of retraction.