Discussion
cancer, tumor, irresponsiveness
REGRESSION, CANCER, TUMOR, METASTASIS
Currently, the low incidence rate and high heterogeneity hindered further investigation of GNEC [Based on the univariate and multivariate Cox regression analysis, ten parameters (age, gender, grade, T stage, N stage, metastasis, primary site, tumor size, RNE, and chemotherapy) significantly affecting CSS in postoperative GNEC patients were enrolled in the predictive nomogram. By examining the max points of the integrated parameters in the model, grade and TNM stage were regarded as highly significant variables influencing the prognoses. Previous research had shown how these risk variables and GNEC were related. Hu et al. investigated current GNEC epidemiological trends and developed a nomogram to assess these patients’ prognoses. According to the findings, the survival of GNEC was substantially correlated with grade, T, and N staging [It was reported that GNEC patients presented irresponsiveness to traditional chemotherapy [Currently, the AJCC TNM staging system is the main option for cancer prognosis prediction. However, its application in GNEC patients has recently been called into question [