Conclusion
We have shown that mapping EQ-5D with each of VitiQoL, VNS and clinical measures such as RPS is plausible. Mapping with VNS and RPS appears to show superior performance than with VitiQoL and a relationship between EQ-5D-5 L utility, VNS, VitiQoL and RPS can be considered as a basis for defining clinically meaningful HRQoL differences.