Diagnostic performance of clinical presentation
HAT, itching, weight loss, weight loss and motor disorders
MOTOR DISORDERS, AFRICAN TRYPANOSOMIASIS
The diagnostic performance of (co-)occurrence of the 4 clinical symptoms and signs that were associated singly or in combination with HAT, namely enlarged lymph nodes in the neck, severe itching, important weight loss and motor disorders, was studied in function of the HAT status in 48 HAT and 2297 non-HAT affected study participants (Table The diagnostic performance of occurrence of 4 key clinical presentations for human African trypanosomiasis (HAT) diagnosisSensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of occurrence of presence of enlarged lymph nodes in the neck and/or important weight loss and/or severe itching, and/or motor disorders were determined for identification of HAT patients. The occurrence of at least one symptom or sign (≥ 1/4) and co-occurrence (≥ 2/4; ≥ 3/4 or all 4/4) of the 4 selected clinical presentations was counted in 48 HAT patients and 2297 non-HAT affected study participants, and proportions (