Association of Traditional Glycemic and Nonglycemic Risk Factors and Microvascular and Macrovascular Complications With MRI Outcomes Among 416 EDIC Participants, Adjusted for Age, Sex, and Scanner 
PDR, seizure, high-density lipoprotein, coma, Diabetes, CSME
SEVERE HYPOGLYCEMIA, PROLIFERATIVE DIABETIC RETINOPATHY, CLINICALLY SIGNIFICANT MACULAR EDEMA, DISEASE, COMA, DIABETES, EVENTS, COMPLICATIONS
Abbreviations: AER, albumin excretion rate; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CSME, clinically significant macular edema; DCCT, Diabetes Control and Complications Trial; EDIC, Epidemiology of Diabetes Interventions and Complications; eGFR, estimated glomerular filtration; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MRI, magnetic resonance imaging; PDR, proliferative diabetic retinopathy; SPARE-AD, spatial pattern for recognition-Alzheimer disease; SPARE-BA, spatial pattern for recognition-brain age.Data are β coefficients, standard errors, Risk factors were characterized by the time-weighted mean values of all follow-up values since DCCT baseline up to the MRI study visit.Severe hypoglycemia was defined as events leading to coma or seizure documented by self-report for the 3-month period prior to each visit.Any report between DCCT baseline and the MRI study visit.