Implications for clinical practice
MH, opioid use disorder
This study has some implications for clinical practice. In view of that, the findings highlight the effect of zinc supplementation on reducing the PoR and improving MH in patients with opioid use disorder experiencing MMT. Therefore, healthcare providers can introduce zinc supplements into the treatment plans for such individuals to help diminish their PoR and enhance their MH. However, further research is needed to replicate such outcomes. In addition, more studies are recommended to reflect on the challenges facing zinc administration in clinical practice from the perspective of healthcare providers and patients with opioid use disorder undergoing MMT, which can aid in making decisions for the inclusion of zinc supplements into the treatment plan of this group.