Ethics approval and consent to participate
This study was performed in accordance with the principles of the Declaration of Helsinki. Ethics approval was obtained from the Ethics Committee of Geneva, Switzerland (project ID 2020 − 01010) and registered in the Swiss National Clinical Trial Portal (SNCTP000003978) and ClinicalTrials.gov (NCT04558073, 22/09/2020). All participants signed a written informed consent form before participating in this study.