Assessment of tumor response and toxicity
tumor, death
DISEASE PROGRESSION, TUMOR, ADVERSE EVENTS, DISEASE, SECONDARY
The primary endpoint was PFS, and the secondary endpoints included OS, tumor response including objective response rate (ORR) and disease control rate (DCR), and adverse events. PFS was calculated from the start of treatment to the date of either disease progression or death or censored at last follow-up. OS was defined as the time from treatment initiation to final follow-up or until death from any cause. PFS and OS were calculated using the Kaplan–Meier method based on follow-up information, which was received until September 2021. ORR were evaluated with CT every 8 weeks until disease progression or death or censored at last follow-up using RECIST guidelines (ver. 1.1) [