Availability of data and materials
Processed methylation and hydroxymethylation data used as inputs for the analyses as well as processed RNA sequencing data have been deposited at the European Genome–phenome Archive (EGA; https://www.ebi.ac.uk/ega/) under accession number EGAS00001006916. A data access committee has been established to ensure that the intended use of data is compatible with the requirements of the European General Data Protection Regulation (GDPR) and consistent with the consents given.
R-scripts used to generate methylation and hydroxymethylation plots are available at Zenodo (zenodo.org, 10.5281/zenodo.7500493).
The input for the demethylation model is provided in Additional file 