Conclusions
stroke, death
STROKE
In this exploratory post hoc analysis of a large, randomized trial of older individuals with additional stroke risk factors, higher NT-proBNP levels at baseline were associated with increased risks of AF diagnosis, stroke, and death. Compared with usual care, long-term continuous screening with ILR and subsequent OAC initiation upon AF detection were associated with a significant reduction in stroke risk among individuals with higher NT-proBNP levels but not among those with lower levels. These findings should be considered hypothesis generating, and future studies are warranted to assess the net benefits of AF screening according to NT-proBNP.