INTRODUCTION
Stomatitis, bleeding, diarrhea, stomatitis, caries, pain, mandibular fracture
STOMATITIS, BLEEDING, STOMATITIS, PERIODONTITIS, WOUND INFECTION, DENTAL PLAQUE, CARIES, COMPLICATION, POSTOPERATIVE INFECTION, BACTERIAL RESISTANCE, CAVITY, SECONDARY INFECTION
It has long been known that the oral cavity is a breeding ground for bacteria, because it is not only maintained at a constant temperature, but it is also a moist environment (Aas et al., Under normal circumstances when homeostasis is maintained, individuals are able to coexist with the commensal resident intraoral biota by means of their own immunity and natural purification. However, diminished immunity in the periprocedural period (whether the procedure involves surgery, radiotherapy, chemotherapy, or other treatment) or due to age means that homeostasis can no longer be maintained, and a range of problems can occur, including wound infection, stomatitis and resulting secondary infection, caries, and periodontitis. Stomatitis is a particular issue during radiotherapy and chemotherapy, and since it causes bleeding and pain, mechanical cleaning becomes difficult (Saadeh, Special conditions caused by surgery are also known to affect the oral environment in various ways. For example, patients with a mandibular fracture and those who have undergone orthognathic surgery may undergo maxillomandibular fixation to encourage bony healing, but this means that they are unable to open their mouths and cannot eat by mouth for a certain period. The most common complication after these surgeries is postoperative infection. Antimicrobial administration plays an important role in the prevention of postoperative infections, but carries the risk of diarrhea and the increasing bacterial resistance (Thornhill et al., HABITPRO mouthwash contains the following three active ingredients: cetylpyridinium chloride (CPC), dipotassium glycyrrhizinate (GK2), and tranexamic acid (TXA), which are expected to have bactericidal, anti‐inflammatory, and hemostatic effects.The objective of this study was to investigate the effect of continued perioperative use of HABITPRO mouthwash with mechanical cleaning on the intraoral environment, particularly in patients undergoing maxillomandibular fixation, which is a specific treatment used in dental and oral surgery. Specifically, the intraoral environment was evaluated by testing the amount of dental plaque and salivary properties to investigate the effectiveness of this mouthwash during maxillomandibular fixation.