Study design
mouth-breathing
BLIND
This is a randomized, single blind, parallel, controlled study to evaluate the efficacy of nasal splinting and mouth-breathing training in preventing ED in adults after FESS. Adult patients were 1:1 randomly allocated to receive preconditioning treatment or control treatment. The random sequences were generated by computer and concealed until the patients were included. Patients in the preconditioning treatment group received nasal splint and mouth-breathing training before FESS, and no any interventions were performed in the control group. The study protocol has been approved by the Shanghai General Hospital Institutional Review Board (IRB 2019KY039) and was registered prior to patient enrollment at chictr.org.cn (ChiCTR1900024925) [