Trial design {8}
chronic pain, fibromyalgia
CHRONIC PAIN, FIBROMYALGIA, ADVERSE EFFECTS
The SPIRAL study is an open-label randomized controlled trial. Patients with chronic pain from fibromyalgia will be randomized 1:1:1 to receive daily oral oxycodone, inhaled Bediol®, or oral oxycodone combined with inhaled Bediol®. The study is coordinated by a single center from which the patients receive their medication; all patients will be treated at home. We hypothesize that adverse effects will be less in the groups that receives oxycodone combined with Bediol® (superiority design).