Limitations
ADVERSE EFFECTS

Our study has several limitations that should be acknowledged. Firstly, the sample size was relatively small, which may limit the generalizability of our findings. Additionally, the absence of a placebo control group restricts our ability to establish a direct comparison between the intervention and a non-treatment condition. Future investigations incorporating larger sample sizes and including a placebo control group are warranted to validate our results and provide further insights into the long-term effects of this combination therapy. Furthermore, longer follow-up periods and studies exploring the optimal duration and frequency of dexmedetomidine administration would be beneficial in enhancing our understanding of its therapeutic potential. Finally, additional research is warranted to investigate the safety and potential adverse effects of dexmedetomidine, particularly in vulnerable populations such as elderly patients and those with comorbidities.