Acknowledgements
The trial was designed by the REVISE steering committee including national and international management committees, the REVISE investigators and research coordinators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. We are grateful to others at the Methods Center at McMaster University (Lisa Buckingham, France Clarke, Mary Copland, Karlo Matic, Ashley Sawyer, Alyson Takaoka) and The George Institute (Fatima Butt, Anna Cheng, Conrad Nangla, Fiona Osborne, Tina Schneider, Isabella Schoeler, Anna Tippet) for their expertise. We appreciate the suggestions of Drs. Neill Adhikari, Dean Fergusson, and Mark Borthwick on this report.