Introduction
liver and skeletal muscle, cardiovascular and renal functions
Edited by: Bilgen Ekim Üstünel, Heidelberg University Hospital, GermanyReviewed by: Shawn R. Campagna, The University of Tennessee, United States; Absalon Gutierrez, University of Texas Health Science Center at Houston, United States†These authors have contributed equally to this work and share first authorshipAtrial natriuretic peptide (ANP), a hormone secreted from the heart, controls cardiovascular and renal functions including arterial blood pressure and natriuresis. ANP also exerts metabolic effects in adipose tissue, liver and skeletal muscle, and interacts with the secretion of adipokines. We tested the hypothesis that ANP lowers concentrations of the anorexigenic adipokine leptin in healthy humans 