Plasma biochemistry
The intervention decreased plasma triglyceride levels by 22% in the OM3FLAV group by 3 mo, with no change in the control group (Plasma biochemistry at baseline and in response to interventionData are mean (SD); ANCOVA using mixed models for repeated measures, with change from baseline (ie, 3 mo-0 mo and 12 mo-0 mo) fitted as a fixed repeated factor (2 levels: 3 and 12 mo), and center, age, sex, and BMI added as covariates. BDNF, brain-derived neurotrophic factor; HDL, high density lipoprotein; OM3FLAV, omega-3 polyunsaturated fatty acids (EPA+DHA; OM3) + cocoa flavan-3-ols (FLAV).