Conclusions
reductions in blood biomarkers of inflammation
STERILE
In this single center Phase I/II randomized, double blinded, placebo-controlled trial, daily intravenous administration of 10 cc of sterile filtered, acellular human amniotic fluid for 5 days among patients hospitalized for COVID-19 did not result in statistically significant reductions in blood biomarkers of inflammation or efficacy outcomes. In addition, despite some of the stated limitation of the trial, this is the first study to demonstrate that intravenous hAF can be safely administered to hospitalized patients.