Outcomes
infection, WED
INFECTION, WED, SCAR
Primary outcome was to show that significantly higher percentage of WED-treated samples showed decreased biofilm severity compared with SoC treatment measured at day 7 using SEM (gold standard for biofilm analysis) imaging and quantification of wound biopsies. Secondary outcomes were to show that a significantly higher percentage of WED-treated samples showed decreased overall infection compared with SoC treatment measured at day 7 using standard clinical microbiological analyses. In addition, impact on visual and functional wound closure and wound quality (scar outcomes) was assessed secondarily with the following caveat: the direct impact of acute WED treatment (only for 7 days) on these long-term outcomes cannot be objectively evaluated.