References
high-density lipoprotein
REGRESSION
Flowchart of enrolment, intervention allocation, and data analysis.Concentrations of bone markers and BMD levels in the groups at baseline and after 12 months. The figure shows the concentration of (Percentage changes in all osteoblastic/osteoclastic parameters and BMD between the placebo and active groups were evaluated. The percentage changes in all bone metabolism markers and BMD were significantly different between the placebo and active groups. The dots represent the outliner values.Linear regression analysis by group. In the placebo group, no predictors of changes in BMD were identified. Conversely, in the intervention group, a statistically significant association was found between the percentage changes in BAP and the percentage changes in BMD.Baseline characteristics of study participants.Abbreviations: SBP, Systolic blood pressure; DBP, Diastolic blood pressure; BMI, body. mass index; LDL, low-density lipoprotein; HDL, high-density lipoprotein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; DPD, deoxypyridinoline; TRACP-5b, tartrate-resistant acid phosphatase 5b; BAP, bone-specific alkaline phosphatase; BMD, bone mineral density.Multivariable linear regression analysis.In bold the significant values are reported.