Continuous outcomes
REGRESSION
Results are shown in Difference in estimates from participant-average estimators versus cluster-average estimators and mixed-effects models for continuous outcomes. Treatment effects are differences in means (restrictive versus liberal transfusion strategy), presented with 95% CIs.CI: confidence interval; IEEs: independence estimating equations; EQ-5D: EuroQol-5D; VAS: visual analogue scale.Estimated using GEEs with an independence working correlation structure with cluster-robust standard errors and equal weight for each patient.Estimated using a linear regression model applied to unweighted cluster-level summaries.Bland–Altman plot of percent difference between cluster-average versus participant-average effects. (a) shows results for continuous outcomes and (b) shows results for binary outcomes.CA: cluster-average. PA: participant-average. OR: odds ratio.