Comparisons
CPD
For results in which a change from baseline could be measured (CPD and SASEQ), each participant’s baseline data served as their control to then calculate a difference at 52 weeks, and a paired 2-tailed In the assessment of quit rates (self-reported and biovalidated PPA, self-reported and biovalidated continuous abstinence, and self-reported abstinence from all tobacco products), 2 sets of analyses were performed. In the ITT analysis, individuals who did not respond to the PPA questions were assumed to be smoking. A study responder analysis was also performed, which only included individuals who completed the 52-week questionnaire. For the outcomes of quit attempts and the proportion of participants who reduced CPD by ≥50%, a study responder analysis was performed.