Symptoms: VAS
PL9643, itching, −4.7, pain
PL9643 treatment showed nonsignificant numerical improvement over placebo in LS mean change from baseline at week 2 for the VAS symptoms of itching (−1), foreign body sensation (−5.1), eye discomfort (−7.4), and eye dryness (−4.5). The treatment effect of PL9643 was generally maintained throughout the study for symptoms of eye discomfort, eye dryness, and itching from week 2 to 12. The greatest LS mean treatment differences at week 12 were observed for pain (−4.7) and itching (−3.0) (