Participants and ethics
From November 2021 to December 2021, the study enrolled patients aged 18 to 65 years at the Sixth People’s Hospital of Yancheng City (Jiangsu Province, China). The subjects enrolled met the following inclusion criteria: (i) men and women aged from 18 to 65 years old, half from each group; (ii) confirmed diagnosis of The experimental scheme was approved and implemented by the Yan Cheng People’s Hospital Research Ethics Board (approval no. of the ethics committee: ET2021085) and registered in the Chinese Clinical Trial Registry (Registration Number: ChiCTR2100053710). The Declaration of Helsinki and pertinent local laws were followed during the planning and execution of this study. All study participants signed an informed consent form.Gastrointestinal Symptom Rating Scale (GSRS) (