Conclusion
wheezing, asthma, wheeze
ASTHMA
In summary, the ADEM2 project covers 3 main areas. First, a multicentre RCT will be performed to assess the hypothesised gain in health and reduction of health care related costs by means of a proper early diagnosis using the breath test in wheezing preschool children. Second, the longitudinal observational cohort study is set up to unravel early and important pathogenic mechanisms of asthma and transient wheeze. And third, this project facilitates the development and assessment of the diagnostic potential of alternative VOCs sensing techniques besides GC-tof–MS as well as other multi-omics measurements.