5. Conclusions
obesity, metabolic alterations
OBESITY, PATHOLOGY, DYSFUNCTION
According to our findings, MASLD phenotype changes as this dysfunction progresses, involving a switch in amino acid use. The assessment of ALT, proline, alanine, and Matsuda Index could be considered as metabolic signatures of MASLD in children living with obesity. However, more studies are necessary to broaden the knowledge about metabolic alterations in MASLD in order to prevent and identify this pathology during childhood, as well as its comorbidities, in addition to improving clinical treatment.