ABC pathway implementation
thromboembolic, hypertension, bleeding
BLEEDING, HYPERTENSION, HEART
Centres randomized to the mAFA intervention implemented the ABC pathway defined as follows:‘A’ criterion: OAC treatment according to regular and dynamic re-assessment of thromboembolic and bleeding risks, with dose adjustments based on regular evaluation of renal and liver function;‘B’ criterion: regular assessment of patient-reported symptoms, evaluated according to the European Heart Rhythm Association classification, and treated according to symptoms-directed management (including rhythm control therapies);‘C’ criterion: management and optimization of concurrent comorbidities (e.g. hypertension management according to blood pressure monitoring, etc.).Patients allocated to “usual care” group were managed according to local practices.