Ethics considerations
Ethics approval was granted by the Clinical Research Ethics Committee of Aragon (PI21/139 and PI21/454). The procedures carried out for the creation of this work complied with the ethical standards of the previously mentioned committee and with the 1975 Declaration of Helsinki. All of the subjects signed an informed consent form, their data were anonymised and will only be used for the purposes of the study. Participants and healthcare professionals will be informed about the results. The ethics committee will be notified of any protocol modifications.