Institutional Review Board Statement
This study was conducted in accordance with the Declaration of Helsinki. Formal ethics approvals (and amendments, due to COVID-19 insurgence) were obtained from the ethical review boards of the University of Bologna (Italy) (116994; 144521), University of Ljubljana (Slovenia) (20 August 2019; 20 April 2020; 20 August 2020), Vrije Universiteit Amsterdam (the Netherlands) (ERB/19-08-02; ERB/20-04-01) and University of Sussex (United Kingdom) (ER/FML24/5; ER/FML24/6) and from the Swedish Ethical Review Authority (2019-04285; 2020-03057). According to the National Human Research Act, the Ethics Committee of the Zürich Canton (Switzerland) deemed formal ethical approval unnecessary (2019-00995). However, detailed opinions were duly sought and gained by SKF accordingly. This study was registered at clinicaltrials.gov (trial registration number: NCT04114864).