Study design and participants
end-stage diseases, chronic infectious disease
DISEASE, CHRONIC INFECTIOUS DISEASE
This is a randomized, open-label, and parallel-group clinical trial. We followed the CONSORT checklist of reporting of randomized control trial (We excluded pregnant, breastfeeding, attempting to conceive, had end-stage diseases, had an active or chronic infectious disease, had any disease that compromises immune function, and had hemoglobin concentration below 12 g/dl, platelet count below 130 × 10