Tumor immune evasion, immunotherapy response, and drug susceptibility analysis
Tumor
IMMUNE DYSFUNCTION, TUMOR
The Tumor Immune Dysfunction and Exclusion (TIDE) scoring file of patients was obtained from the TIDE website, which focuses on TIDE and used to determine possible variation in the response to immune checkpoint blocking among patients in both groups, using the software package “ggpubr.”We performed a drug susceptibility analysis to assess the difference in drug susceptibility between patients in high and low risk groups. The evaluation criterion was the IC50 value, representing the semi-inhibitory concentration of the drug being tested. Lower IC50 measurement indicates better drug sensitivity. For this analysis, we employed the R package “pRRophetic.”