Data analysis
PLAQUE
Study data were entered into Statistical Package for Social Sciences version 25 (SPSS Inc., Chicago, IL, USA) using anonymous patient codes. The baseline characteristics and the clinical outcomes were reported as mean with standard deviation for the continuous variables (age, Plaque Index, and PISA values). These variables had normal distributions i.e., tested for normality using the Shapiro–Wilk test, hence were analyzed using mixed model analysis of variance to enhance the capabilities of greater statistical power. The categorical variables of baseline characteristics were presented as frequencies and percentages, which were tested using Fisher’s exact test. Statistical significance was set at the 95% confidence level (α = 0.05), in which a 