INTRODUCTION
fits, LS, colorectal cancer, cancers, Lynch syndrome
CANCERS, COLORECTAL CANCER, LYNCH SYNDROME
Lynch syndrome (LS) is an inherited condition that increases the risk of developing several cancers, including colorectal cancer.Aspirin prescribing is likely to occur in primary care, but GPs may be reluctant to do so.The optimal type and level of information to communicate with GPs was investigated to increase their willingness to prescribe aspirin to a patient with LS. GPs were presented with one of eight versions of a patient vignette, manipulating the presence or absence of three types of information on the effectiveness of aspirin for colorectal cancer prevention:
existence of NICE guidance (NG151);results from the CAPP2 trial;information comparing the risks and benefits of aspirin.The main effects of each manipulation on willingness to prescribe aspirin and comfort with discussing aspirin were hypothesised. As exploratory research, two-way and three-way interactions between these main factors on the outcomes were investigated, and barriers and facilitators to prescribing aspirin among GPs examined.How this fits in