1.3. Study Objectives
The study objective was to enhance participants’ willingness, motivation, trial literacy, or altruism towards trial participation through a personalized and decentralized education and navigation app compared to the traditional one-size-fits-all centralized trial experience. This app was designed to inform, educate, engage, support, and navigate participants through clinical trial experience, with a strong focus on personalization. To accomplish this, we first conducted qualitative assessments to identify facilitators for increasing participation in decentralized trials. Then, we incorporated these elements into the app’s design and functionality. Our comprehensive approach aims to assess whether this personalized strategy significantly improves participant adherence, retention rates, and overall engagement throughout the clinical trial process. Furthermore, we aim to explore the potential impact of these strategies on the representation of historically underrepresented groups in clinical trials, offering a wide variety of research volunteer opportunities, including clinical trial participation, to cater to diverse individuals and encourage their engagement in research studies. 