Interventions
PMBL, catarrhalis, Streptococcus viridans, Haemophilus influenzae, ozaenae
RESPIRATORY INFECTIONS, KLEBSIELLA PNEUMONIAE, STAPHYLOCOCCUS AUREUS, KLEBSIELLA
The study used PMBL obtained by sonification, whereby ultrasound is used to inactivate the bacterial cell wall (Ismigen, Lallemand Pharma AG, Switzerland). The product is available in the form of sublingual tablets containing 7 mg of bacterial lysate of the following bacteria: Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridans, Staphylococcus aureus, Neisseria catarrhalis, Haemophilus influenzae, Klebsiella pneumoniae and Klebsiella ozaenae. PMBL was taken by patients according to its dosage regimen in recurrent respiratory infections. Thus, children in the PMBL group received 3-cycles of PMBL treatment, each consisting of sublingual administration of one PMBL tablet on an empty stomach for 10 consecutive days followed by a 20-day break (