Study design
RECRUITMENT, -20
This was a three-arm, parallel-group, randomized trial. The study was conducted at the Basic Sciences Laboratory, Universidad San Sebastian, Valdivia, Chile. Recruitment was conducted through social media and email during the months of June, July, and August 2022. The study protocol was approved by the Scientific Ethics Committee of the University of Granada, Spain (2380/CEIH/2021) and of the Universidad San Sebastián, Chile (55-2021-20). It has also been registered in the Protocol Registration and Results System (