Manufacturing of T cell product
The manufacturing process (approval number by Government of Oberfranken (DE_BY_05_MIA_2014_0045/55.2-2678.3-6-1) for the T cell product has been described previously (Peptides used for HLA multimer analysis of virus-specific CD8+ T cells.To assess the presence of CMV/EBV specific CD8+ T cells before and after the T cell product application flow cytometric analysis using peptide loaded HLA multimers was used. The HLA multimers used were selected according to the presence of the HLA genotype of the patient.