NSCLC, tumor, melanoma, Tumor, NSCLC A549
TUMOR, MELANOMA, TUMOR, NSCLC, TUMOR GROWTH
For syngeneic tumor studies, wild type 6–8 weeks old female BALB/c mice (Harlan/Envigo, RRID:IMSR_APB:4790) were implanted subcutaneously with 1 × 10For human NSCLC A549 (1 × 10Humanized patient xenograft studies were performed in recipient 3-week-old NSG mice, who were engrafted intravenously with CD34In all human xenograft studies (NSCLC A549, melanoma A2058, and BR1126 PDX), tumor growth was measured two to three times per week after randomization until only tumor-free mice remained on study. Tumor volume (denoted as mm