Adherence
depression, fatigue, ’
Treatment adherence for the face-to-face CBT was defined as attending at least three treatment sessions, including a session at the end of the 20-week period. For the blended CBT, adherence was defined as attending the first and last treatment sessions, and opening at least the MS Fit modules ‘sleep and rest’ and ‘physical activity regulation’ as an indication that patients actively started MS Fit. Adherence also included not receiving other treatments for fatigue and not shifting the focus of treatment to other occurring co-morbidities such as depression. Patients who dropped out during the treatment period were requested to complete the questionnaires at week 20.