Conclusion
CIPN
DISEASE PROGRESSION
Despite these limitations, our study further supports that decreasing the chemotherapy regimen is associated with increased odds of disease progression, an effect not explicitly studied in recent work. Additionally, this study highlights an increased BMI as a risk factor for worsened CIPN. Better understanding and validation of these risks provide opportunities to identify those patients at risk for CIPN and interventions to mitigate the modifiable risks associated with this condition. CIPN remains a highly relevant clinical challenge and further research in risk characterization and optimization is needed.