Pharmacokinetic data
Pharmacokinetics of ANTHRASIL were evaluated in the rabbit study, and systemic exposure with IV infusion of 15 U/kg was confirmed. Twelve of the 16 animals that survived past Day 7 exhibited a humoral immune response to PA, with large increases in concentrations of anti-PA antibodies observed using both the Toxin Neutralization Assay (TNA) and Enzyme-Linked Immune-Sorbent assay (ELISA) (