Ethics approval and consent to participate
WEST
The protocol was approved by the National Health Service (NHS) South West – Frenchay Research Ethics Committee (Ref: 22/SW/0084), conducted in accordance with the Helsinki Declaration of 1975, as revised in 2000, and registered on ClinicalTrials.gov (Identifier: NCT05439252, 30/06/2022). Informed consent was obtained from all the participants.