Background
Hepatocellular carcinoma, malignancy, hepatocellular carcinoma, tumour
HEPATOCELLULAR CARCINOMA, HEPATOCELLULAR CARCINOMA, RECURRENCE, TUMOUR
Hepatocellular carcinoma is the sixth most common malignancy in the world. Major hepatectomy (resection of greater than or equal to three liver segments) is needed if a tumour is large or close to major blood vessels. Despite low mortality, open major hepatectomy is associated with high rates of tumour recurrence that limits survival. Laparoscopic major hepatectomy has been proposed as an alternative approach with potential oncological benefits. This study compares laparoscopic major hepatectomy with open major hepatectomy for hepatocellular carcinoma in a randomized trial.