Statistical analysis
±, SD
Categorical variables were expressed as frequency (percentage age), normally and nonnormally distributed variables were expressed as the mean ± SD and the medians with interquartile ranges, respectively. The Pearson test was used for the correlation analysis. Between the groups and the different times, repeated measurements data were analyzed by repeated measured variables. Differences between the groups measured at the same time points were performed using Student’s two-sample t test or the Mann-Whitney U test. The limit of statistical significance was set to 