4. Discussion
human emotions and stress
PROLIFERATION, DISEASES
This study confirmed that Lp N1115 can help maintain the intestinal pH of infants aged 6–24 months after C-section, improve immune function, and promote the proliferation of We found that the stool pH of the control group increased significantly after the intervention. Although the fecal pH of the test group increased, the change was not significant compared with baseline. Some researchers have reported that after an intervention with The intestinal microflora can affect human emotions and stress levels through the microbiota–gut–brain axis [We found that the stool sIgA of the Lp N1115 intervention group showed an upward trend while that of the control group showed a downward trend, but only statistically significant differences were detected in the 6–12-month-old group, which may be due to factors such as weaning at 6–12 months and supplementary food addition, which accelerated the development of infant humoral immunity and which made them more susceptible to probiotics. The overall intervention effect on saliva sIgA was not obvious. However, the study of Brandtzaeg et al. suggests that the correlation between salivary sIgA and the intestinal sIgA reaction is weak [Compared with infants delivered naturally, the delayed colonization of bifidobacterial and lactobacilli in infants delivered by C-section may affect intestinal development to a certain extent [The infant intestinal flora is affected by many factors. A review published in 2021 further clarified that C-section has a certain negative impact on infant intestinal microecology balance and health outcomes [In order to understand the relevant mechanisms linking changes in the bacterial flora composition and the health effects of probiotic intervention, this study attempts to analyze the relationship between the intestinal flora and biochemical indicators and diseases. The results showed that the correlation between The use of This study has certain limitations. First, considering the particularity of infants and young children, this study has included infants and young children from the age of 6 months. Most of the study subjects had complementary foods added to their diets, and there were many confounding factors that may have covered up the intervention effect to a certain extent. In addition, to avoid invasive tests such as blood collection, only saliva and stool samples were collected in this study, and the biochemical indicators measured were of limited representativeness. This study is a preliminary exploration of the application of Lp N1115 in infants and young children, and a control group of infants delivered naturally and young children was not included in the design. The extrapolation of the results is limited, and the long-term impact of the Lp N1115 intervention cannot be obtained.