Inclusion criteria
amenorrhea
STERILE
Each participant must meet all of the following criteria to be enrolled in this study:Male or female, at least 18 years of age at the time of consent (Screening Visit).Investigator’s assessment that participant understands and is willing and physically able to comply with protocol-mandated follow-up, including all procedures.Participant has provided written informed consent for participation in this study, including all evaluations and procedures as specified in this protocol.Female participants of nonchildbearing potential may be enrolled in the study.Nonchildbearing potential is defined as surgically sterile (history of bilateral tubal ligation, bilateral oophorectomy, hysterectomy) or postmenopausal (defined as amenorrhea for ≥12 consecutive months before Screening (day 0) without an alternative medical cause). A follicle-stimulating hormone level may be measured at the discretion of the investigator to confirm postmenopausal status.Female participants of childbearing potential may be enrolled in the study if the participant fulfills all of the following criteria:Has a negative pregnancy test on the day of vaccination (day 1)Has practiced adequate contraception or has abstained from all activities that could result in pregnancy for at least 28 days before day 1Has agreed to continue adequate contraception through 3 months following vaccinationIs not currently breastfeeding(Adequate female contraception is defined as consistent and correct use of a Food and Drug Administration-approved contraceptive method in accordance with the product label)Participant must have been either previously enrolled in the phase 3 mRNA-1273 COVE trial