Team structure
The EAGLE team comprised separate Protocol Writing and Education Committee groups to drive forward the study design and the educational resources independently. The Operations Committee was convened to deliver the study with ‘Meta-coordinators’ liaising between the central team and ‘Coordinators’ who were responsible for day-to-day liaison with collaborators from individual clusters, loosely divided into geographical groups of hospitals or by language (Fig. EAGLE team structure showing relationships between committeesEAGLE Coordinators worked with local Principal Investigators (PIs) to ensure that relevant local approvals were realised. Any regional or national ethical approvals were shared with other members of the same jurisdiction to minimise duplication of work. Resources and approvals were disseminated by close communication between PIs, coordinators and meta-coordinators.