Secondary outcomes
pain
MOS, FIBROMYALGIA
Questionnaire analysis is summarized in Fibromyalgia related symptoms and pain questionnaires demonstrated significant improvements induced by HBOT. In both FIQ and GPS score, the HBOT group improved with a significant group-by-time interaction, and a large net effect size of (d = -1.11, p = 0.0001) and (d = -0.91, p = 0.001).Regarding quality of life, the HBOT group improved in most health domains of the SF-36 questionnaire. Most significant domains were energy, social function, and pain with group-by-time significant interactions of (d = 1.08, d = 1.08, d = 0.11, p<0.0001). In the MOS, the HBOT group improved in sleep problems index, with a significant group-by-time interaction (d = -0.65, p = 0.018).Improvements in psychological symptoms were also demonstrated after HBOT. In the BSI, the HBOT group improved in the total and the somatization scores, with a significant group-by-time interaction (d = -0.69, p = 0.012) and (d = -0.95, p = 0.001). Post-HBOT improvement was also found in the BDI score, with a significant group-by-time interaction and a large effect size (d = -0.80, p = 0.004). Correlations between all questionnaire domains is illustrated in Changes in PPT and CPM-PPT are illustrated in 