Standard procedure
neurogenic intestinal dysfunction, TNF-α, postoperative arrhythmia, dizziness, NB, shivering, neurogenic bladder
BLOOD, NEUROGENIC BLADDER, ADVERSE EFFECTS
Dynamic monitoring of vital signs, intravenous indent needles, non-invasive blood pressure, electrocardiogram (ECG), heart rate, pulse oxygen saturation, and bispectral index were monitored when the patient entered the operating room. The trial was designed with an initial lidocaine (Hunan Kelun Pharmaceutical Co., Ltd, F210625c) load of 1.5 mg/kg for 10 min, followed by an infusion rate of 2.0 mg/kg/hour until the end of the procedure5 ml of blood was drawn from a peripheral vein before induction of anesthesia and 48 hours after surgery in all patients. Blood samples were centrifuged for 5 min at 10,000 rpm and stored in a refrigerator at − 80 °C for subsequent testing. Enzyme-linked immunospecific assay (ELISA) was used to test IL-6, IL-10, and TNF-α plasma concentrations by commercially available kits (eBioscience Co., Ltd., San Diego, USA). The incidence of patients with postoperative arrhythmia, dizziness, shivering, and adverse effects within 48 hours after surgery. The occurrence of neurogenic intestinal dysfunction (NID) and neurogenic bladder (NB) was recorded until the patient was discharged.