Headache characteristics and diary
migraine, headache
MIGRAINE, ADVERSE EVENTS
A headache specialist conducted a semi-structured interview at the screening visit. The interview included information on medical history, headache characteristics and frequency, family history of migraine and prior pharmacological treatment; these data were confirmed by review of medical records.On the experimental study days, investigators recorded data on headache characteristics, vital signs and adverse events every 10 min for 90 min after administration of the experimental trigger. After the in-hospital phase, patients were discharged with a 12-h headache diary for hourly recordings of headache features, accompanying symptoms, intake of any rescue medication and adverse events.