Limitation
One of the main limitations of the present study is the lack of indirect costs calculations like reduced productivity of interventions and transportation costs. In addition, in this study, the costs of common conservative treatment, such as oral or topical analgesics, physical therapy, and medical equipment were not considered in the cost-utility analyses. The costs considered in the present study may differ in different situations. It is due to different provider perspectives, providing centers (public or private), contractual agreements, insurance status, and so on. Based on the mentioned reasons, it appears that we could not interpret the results for the general population exactly. A wide range of variations of the drugs and kits costs, as well as the medical tariffs, over time, which is considered another limitation, the reproducibility of the results would not be precise. To cope with such problems, in the following studies, the researcher may calculate the exact costs of different treatments and procedures.