2.2. Study Investigational Product
The proprietary, whole-food dietary intervention in the form of softgels was supplied by the manufacturer (Palmyra, WI, USA). The serving size was defined as 2 softgels that contained a blend of full-spectrum hemp oil standardized to 15 mg of phytocannabinoids, calamari oil standardized to 230 mg of omega-3 fatty acids, including 130 mg of DHA and 55 mg of EPA, TrueBroc broccoli extract standardized to 5 mg of glucoraphanin, and a carrier oil (extra virgin olive oil). Other ingredients included gelatin, water, dimagnesium malate, glycerin, and beeswax. The subjects were instructed to consume 1 serving per day (2 softgels in the morning or in the evening) for the duration of the study, and to record their daily supplement intake and weekly chiropractic visits in a study calendar to assess their compliance with the intervention.