Adverse events that do not have to be reported
sensory deficits, pneumonia• urinary tract infection•, stroke, apraxia, numbness, ataxic, neurologic symptoms, poststroke, aphasia
ADVERSE EVENTS, STROKE, ADVERSE EVENT, ISCHEMIC ATTACK, HEART INFARCTION, EVENTS, COMPLICATIONS
More than half of patients experience apparent post-rTMS adverse events, but a substantial proportion of these reported events are rather not related to the investigational treatment but occur as a consequence of the experienced stroke. This may lead to lower specificity for genuine complications of novel treatments and falsely inflate the number of adverse events associated with the therapy. Therefore, events that can be excluded from expedited reporting will be specified (Table Adverse events associated with stroke, that do not have to be reported• falls with subsequent fractures• subsequent stroke or transitory ischemic attack• heart infarction• pneumonia• urinary tract infection• sepsis• dehydration• deliriumPatients with stroke may present with a variety of neurologic symptoms including alterations in vision, changes in speech, focal numbness or weakness, disequilibrium or alteration in level of consciousness, dystextia, dystypia, dysgraphia, aphasia, apraxia, neglect, as well as elementary motor, ataxic, and sensory deficits. Some new deficits may occur within the early subacute period after stroke, or already present ones can deteriorate poststroke (Table 