2.6. Statistical analysis
migraine
MIGRAINE, SECONDARY
Utilizing data from a previously published study utilizing exercise intervention resulting in a significant reduction in migraine days (Kroll et al. [The effects of the time of day of exercise were assessed by comparing Pre- and Post-values from the periods of Morning Exercise (ME) vs. Evening Exercise (EE). We also performed a secondary analysis to test the contribution of participant chronotype on the effects of morning or evening exercise. For the secondary analysis, the time of day of exercise and participant chronotype were grouped into two separate subgroups; In-Sync (IS), were participants who exercised at the time of day most aligned with their chronotype, and Out-of-Sync (OOS), were participants who exercised at a time of day When comparing the average pre- to post-change in outcomes between ME and EE, or IS and OOS, a paired samples 