Sample size calculation
GASTRIC NEOPLASMS
The sample size is calculated on the basis of the primary outcomes.The detection rate of gastric neoplasms and EGC detection rate without AI assistance were determined by literature research. Zhang et al. reported an EGC detection rate of 20.0 to 20.9% [According to our previous study, the detection rate of gastric neoplasms increased by 1.35% when assisted by an AI system; therefore, the detection rate of gastric neoplasms in the experimental group is estimated to be 4.0%. There are no published data evaluating the improvement in EGC detection rates with AI assistance. Thus, we referred to two studies reporting improvements of > 80% in EGC detection sensitivity and proportion [The sample size was calculated, using the To achieve adequate participant enrolment, we first evaluated the annual volume of sedated EGD examinations at all participating centres. The sum of the examination volumes of all centres (> 20,000 per year) is sufficient to provide support for the completion of the study. In each centre, a study coordinator, group of nurses, or endoscopists will be pretrained for informed consent before the examination. Consecutive patients will be informed about the study and assessed for eligibility.