Participant
hepatic and renal insufficiency, neuropsychiatric disease, communication difficulties, cardiorespiratory dysfunction
ACUTE INFECTION, COAGULATION DISORDERS
This was a single-blind randomized controlled trial with a follow-up period of three months that was conducted in Shanxi Bethune Hospital. Forty women who were aged 48-52 years with a gynecologic diagnosis of perimenopausal hot flashes were included in this study. The women had regular menstruation in the past. Women with acute infection, cardiorespiratory dysfunction, hepatic and renal insufficiency, neuropsychiatric disease, communication difficulties, coagulation disorders, who had undergone anticoagulant therapy, or were unable to be followed up were excluded from the study. The clinical trial protocol of this study was reviewed and approved by the Medical Ethics Committee of Shanxi Bethune Hospital (YXLL-2021-083), and registered in the Chinese Clinical Trials Registry (ChiCTR2300070017). All subjects signed the “Informed Consent” form before participating in this study, and all injections were performed by the same experienced anesthesiologist.