General characteristics
aseptic failure, PJIs, PJI, Periprosthetic joint infection
Of the 167 screened cases with suspected hip or knee PJI, 36 cases were excluded due to aseptic failure (n=14), no culture or mNGS testing of synovial fluid (n=10), cement spacers in place at the time of sampling (n=6), unknown antimicrobial-free interval (n=5), and contamination in the operating room (n=1). The remaining 131 cases (84 knees and 47 hips) were included, including 76 cases with previous antimicrobial therapy (Patient demographic and baseline data of 131 PJIs.*The values indicate mean and standard deviation. #The values indicate the number of cases. †The values are the number of cases, with the percentage in parentheses. PJI, Periprosthetic joint infection; MSIS+, MSIS positive; MSIS-, MSIS negative; CRP, C-reactive protein; ESR, Erythrocyte sedimentation rate; WBC, White blood cell; PMN, Polymorphonuclear neutrophil.