Conclusion
In normokalemic patients dietary guidance combined with potassium supplementation and MRA treatment increased p-K levels within weeks whereas total body potassium increased gradually, and a significant increase was seen six months after commencement of the intervention. The differentially regulated p-K and TBK and the slower increase in TBK reflect the challenge in monitoring the potassium homeostasis and the time it may take until all effects of a potassium-regulating treatment can be anticipated.