Multivariate model analysis
The multivariate model analysis procedures were performed under the same criteria as lipidomics. The pre-processing operations gave in case of metabolomics analysis a data matrix based on 5618 entities from full data set.These results showed similar intervention group distributions as lipidomics. The metabolites in plasma samples showed a clear sample grouping, i.e. (VLCHF and VLCHF + HIIT groups) vs. (HIIT and Control groups).