Counselling frequency and content
All participants had adherence counselling at enrolment. The mean number of follow‐up sessions over 18 months was 16.4 (standard deviation [SD]: 3.6). Counsellors reported discussing adherence goal setting, reminder strategies, barriers to adherence, communication skills and product storage at >90% of sessions (Figure DLF was available at 2031 monthly visits (55%), with >1 result available at 29% (Drug‐level feedback results by product and site. A total of 2985 results were returned to participants (1260 for oral PrEP adherence and 1725 for ring adherence), including 854 at the Kampala site (361 oral PrEP, 493 ring); 854 at the Harare site (329 oral PrEP, 416 ring); 516 at the Cape Town site (228 oral PrEP; 288 ring); and 870 at the Johannesburg site (342 oral PrEP, 528 ring).