Conclusion
DISEASE, REMISSION
This feasibility study showed that a future definitive trial to evaluate the effectiveness of MRI to identify disease remission in CN is warranted, feasible and acceptable, to potential participants, healthcare, and research professionals. We recruited 67% of potentially eligible participants and 88% of these completed the active phase of the study. Excluding the disruption caused by the COVID-19 pandemic 94% of study visits and 84% of the intervention MRIs were completed. The absence of any safety incidents supports the feasibility and safety of serial MRIs as the intervention. The results of this study will inform the design, of a full randomised controlled trial.