Study design
MAY, -11
The present study is a randomized controlled clinical trial (RCT) with four parallel arms in a two-factor design. The study was conducted in primary health care in Region Västra Götaland in the south-western part of Sweden. Women aged 45–60 with symptoms often associated with stress were recruited from November 2018 until May 2019 by advertisement in local papers.The study was approved by the Regional Ethical Review Board in Gothenburg Sweden (16/11/2017, registration number 765-17, 2017-11-16). Written informed consent was obtained from all participants and confidentiality was ensured. Trial registration: Universal trial number is U1111-1219-6542 and the registration number in ClinicalTrials.gov is NCT03663075, date of first registration 10/09/2018.