Ethics approval and consent to participate
neurocognitive disorder
Informed consent was obtained from all subjects and from legal guardians of the minors. All experimental protocols were approved by the Institutional Review Boards in all countries and was conducted under Good Clinical Practice per the Helsinki Declaration. The study was approved by several Institutional Review Boards from different countries, and these are listed in Table The study only recruited subjects with capacity to give informed consent. During follow up, whilst some of the subjects developed some neurocognitive symptoms, none was serious enough to make diagnosis for neurocognitive disorder, hence informed consent from LARS was not required.