Statistical analysis
Data were initially analyzed by EpiData ver3.1 and exported to SPSS ver26.0 (SPSS Inc., USA) for further analysis. Data distribution was assessed by the 1-sample Kolmogorov–Smirnov test. Parametric values are expressed as means ± standard deviations. The Wilcoxon test or paired samples t- test for paired samples was performed to evaluate changes between the data obtained at baseline and outcome data. 