Statistical analysis
hypotension
REGRESSION, BLOOD
IBM SPSS 26 Statistics for Windows (IBM Corp., Armonk, NY, USA) was used for statistical analysis, and R Statistics 4.2.2 (R Core Team, Vienna, Austria) was used for visualization. The chi-square test was performed to analyze the primary outcome. The unadjusted and adjusted odds ratio of remimazolam versus propofol for the incidence of hypotension was calculated by logistic regression analysis, and the covariates were the administration of the drugs causing angiotensin axis blockade on the day of surgery and type of surgery.Decrease in the MBP, SBP, and DBP (blood pressure values subtracted from the baseline values) at T1 to T5 were compared using the t-test with Bonferroni correction to correct the multiplicity of the comparisons. The BIS and heart rate at T0 to T5 were compared using the t-test with Bonferroni correction. Other continuous variables were compared using the t-test, and categorical variables were compared using the chi-square test. Statistical significance was set as Blood pressure > 300 mmHg or < 30 mmHg and heart rate > 200 beats per minute were excluded from the analysis. Missing value analysis by SPSS revealed a few missing values (< 5%) in the total remifentanil dose and BIS values; however, they were randomly distributed. The missing values were excluded from the analysis.