Decrease in daily diary score
fatigue, fever, rash, musculoskeletal pain, AGS, headache
The primary effectiveness measure evaluated the decrease in DDS of patients’ signs and symptoms. Daily symptoms, including fever, rash, musculoskeletal pain, headache, and fatigue, were rated with increasing level of severity. Signs and symptoms for NNS/CANDLE, SAVI, and AGS are detailed in Supplementary Table 