Analysis
Patient characteristics, attrition rate, and compliance rate (defined as attending at least 5 out of 6 classes) were compared between intervention and control groups using Wilcoxon rank-sum test for continuous variables and chi-square test or Fisher’s exact test for categorical variables as appropriate. Baseline assessments occurred before randomization, and clinical characteristics pertaining to psychological status could not be controlled. Individual outcomes assessed at T0, T1, and T2 were modeled to examine if there is a GRACE program effect (intervention vs. control) on each outcome over time using a generalized additive model for location, scale, and shape (GAMLSS)Outcomes for each group over time. For all figures