Descriptive analyzes
Emesis
All analyzes were performed as complete case analyzes. Complete case analyzes was chosen because it reflects the ideal situation of the impact of a pharmacist consultation on medication use during pregnancy.We compared the baseline characteristics of the intervention and control groups to evaluate whether the allocation process produced balanced groups. This was also done to evaluate covariate balance, as complete case analyzes put the randomization process at risk. The chi-squared test was used to compare categorical variables, i.e., relationship status, education level, work situation, folic acid supplementation, parity, pregnancy-related conditions, and chronic conditions, which are presented as medians and ranges. Student’s test was used to compare continuous variables, i.e., gestational week, maternal age, and Pregnancy Unique Quantification of Emesis (PUQE) score, which are presented as counts and percentages. Proportions of filled prescriptions of medications and their ATC codes with at least 20 women in the defined time periods as registered in the NorPD were calculated for the five pregnancy periods: three months before pregnancy, the first, second, and third trimesters, and three months postpartum. Filled prescriptions for antiemetic medications were considered for the first and second trimesters only.