3. Results
bradycardia, ±, SD, hypotension, shivering
GROUP B, ADVERSE EVENTS, ADVERSE EVENT, INTRAOPERATIVE HYPERTENSION, HYPERTENSION
A total of 118 patients were recruited for this study, with 59 patients in each group. In total, 114 patients were included in the final analysis, with 55 and 59 patients in the phenylephrine and control groups, respectively. There were 4 drop-outs in the Phenylephrine Group, where the study drug infusion was terminated before the end of surgery due to bradycardia and hypertension. Figure CONSORT diagram.There were no significant differences in the demographic and intraoperative data between the Phenylephrine (Group A) and Control groups (Group B) (Table Demographic and intraoperative data.Values are expressed in mean ± SD or median [IQR] where appropriate. BMI = body mass index, IQR = interquartile range, SD = standard deviation.The incidence of perioperative shivering is shown in Figure Incidence of perioperative shivering. *Table Perioperative shivering score.Values are expressed in number (%). BSAS = Bedside Shivering Assessment Scale.Figure Perioperative core temperature trends. Figure Perioperative blood pressure trends. *Figure Perioperative heart rate trends. *Five patients in the Control Group (8.5%) required rescue pethidine for shivering compared to 1 patient in the Phenylephrine Group (1.8%). However, this difference was not statistically significant (Regarding adverse events, 24 patients in the Phenylephrine Group (43.6%) and 21 patients in the Control Group (35.6%) experienced intraoperative hypotension, which was treated with ephedrine. One patient in the Phenylephrine Group (1.8%) had intraoperative hypertension. Postoperatively, 1 patient in the Control Group (1.7%) had hypertension. There were no significant differences between the groups for any adverse event (