Spike-specific IgG B-cell responses
To further investigate the ability of the boosters to induce antigen-specific B-cell responses, spike-specific IgG spots were detected at baseline and at 28 days and 6 months after booster vaccination in R848-activated peripheral blood mononuclear cells (PBMCs) (Wild-type SARS-CoV-2 spike-specific IgG B-cell responses. 