Ethics approval and consent to participate
This prospective randomized comparative clinical study was conducted in the surgical intensive care unit; Zagazig University Hospitals. The study protocol was ethically approved by Zagazig University?s Institutional Review Board (ZU-IRB#: 6353-23-3-2020) and registration on clinicaltrials.gov was (NCT04539379). The first patient had been enrolled on 1 October 2020 Written informed consent was obtained from all participants after they understood the concept of this research. The study was carried out in accordance with the guidelines and regulations of the Helsinki Declarations.