Patient Characteristics
MYELODYSPLASTIC SYNDROME, ADVERSE EVENT
At data cutoff, March 3, 2022, of the 325 patients screened, 169 patients were randomly assigned eltrombopag (N = 112) or placebo (N = 57; Fig CONSORT diagram. Four patients (one in the eltrombopag arm and three in the control arm) withdrew from the trial before receiving the first dose of eltrombopag; thus, 165 patients (111 patients of the eltrombopag arm and 54 patients of the control arm) were considered in the modified ITT. The first patient was enrolled on June 13, 2011, and the last patient was enrolled on October 1, 2021. At the time of data extraction, 45 patients of 111 of the eltrombopag group and 17 patients of 54 of the placebo group entered the second part of the trial. AE, adverse event; ITT, intention-to-treat; MDS, myelodysplastic syndrome; PLT, platelet.Main Demographic and Clinical Characteristics of Patients