Author contribution
MP
Data were documented by each center into an electronic case report form (eCRF). Statistical analysis and data extraction were performed by KM and MP. THB, DW, SI, KM, and MP wrote the protocol. SI, KM, DW, and THB analyzed the data and wrote the manuscript. Twenty study centers participated in our trial, 16 of them treated pts and collected data. All coauthors reviewed and amended the manuscript and agreed to the final version of the manuscript. We thank Philipp LeCoutre, Christian Junghans, Norbert Gattermann, and Kathleen Jentsch-Ullrich for their participation as investigators.