Effect of dapagliflozin treatment on body weight and adipose tissue thickness
Compared with baseline, we did not observe any significant change in body weight between placebo and treatment group (79.28 ± 4.3 vs 81 ± 4.88 kg, p = 0.19 in placebo group; 83.14 ± 2.5 vs 82.55 ± 3,1 kg, p = 0.2 in dapagliflozin group).We observed a significant 19% reduction of the thickness of EAT in the dapagliflozin group compared to the placebo group (0.74 ± 0.12 vs 0.60 ± 0.10 cm, p = 0.04 in dapagliflozin group; 0.56 ± 0.06 vs 0.55 ± 0.06 cm, p = 0.6) Fig. 