Participants and W-LHIT capsules preparation
obesity
OBESITY
Participants who met simple obesity criteria were recruited from the Weifang community through WeChat Friends Circle, advertisement, and local websites. Inclusion criteria were as follows: age 18-60 years with a body-mass index (BMI) of 28 - 48 kg/mW-LHIT capsules were prepared in a GMP facility (Tian-jiang Pharmaceutical, Jiangsu, China). In our early research, we established HPLC fingerprints of individual herbal components, and monitored the quality of different batches of W-LHIT products by comparing the peak times and intensities of the identified compounds. Berberine was used as a key compound index (