Interventions and Quality Control
METASTASES
The types of surgical interventions are detailed in the previously published study protocol.Furthermore, every surgical specimen was carefully measured according to promotor center indications to assess its quality according with Benz classification.Two types of protocol deviation were recognized: “contamination” for non-CME and “noncompliance” for CME. Contamination was the deviation with specimen picture proof of non-CME quality according to Benz classification (Benz <1), and noncompliance was the absence of complete dissection in the CME group according to Benz classification (Benz >0).The reasons for patient dropout were identification of distant metastases during surgery, a final histopathologic characterization not consistent with the inclusion criteria, and types of surgery performed differently from right hemicolectomy. The follow-up care schedule was reported in the study protocol.