Statistical methods
USA).The
Sample size was calculated according to previous publications (Categorical variables were summarized using frequencies and percentage. Continuous variables were summarized using the median and interquartile range (IQR). Change in bone health parameters post switch to TAF-containing ART was assessed using Wilcoxon rank sum testing. And the Mann-Whithney U test was used to compared both arms.Correlation between changes in bone quality, weight or body mass index were studied using Spearman’s correlation test.All analyses were conducted using Stata 13.1 (StataCorp, College Station, Texas, USA).The trial is registered with EUDRAT (num 2018-004499-36).The institutional review board approved this study, and each participant provided informed consent.