Clinical prediction models
pneumonia, fever, cUTI, bacteraemia, viral infections, bacterial infections
BACTERIAL INFECTIONS, PNEUMONIA, VIRAL INFECTION, COMPLICATED URINARY TRACT INFECTION
The first CPM, Feverkidstool, is a multinomial LRM predicting the risk of pneumonia and other serious bacterial infections (SBI) in feverish children from 10 clinical variables and a POC CRP test [The second model, a CPM constructed by Craig et al. (hereafter named the Craig model), is a multinomial LRM predicting the risk of complicated urinary tract infections (cUTI), pneumonia and bacteraemia in feverish children [In our validation dataset, the broader inclusion criterion of acutely ill children presenting at ambulatory care was used, whereas the derivation of Feverkidstool and the Craig model inclusions were limited to children presenting with fever at the ED [The third CPM, the SBI score, is a risk score assessing the risk of SBI (excluding viral infections) in acutely ill children. It consists of eight clinical items and was derived from a binomial LRM (hereafter named the SBI model) [The fourth CPM, the Pediatric Advanced Warning Score (PAWS), is a risk score based on seven age-specific vital parameters in children [