Keywords
obesity, hemorrhage, VTE, postoperative hemorrhage
OBESITY, HEMORRHAGE, POSTOPERATIVE HEMORRHAGE, POSTOPERATIVE COMPLICATIONS
The prevalence of extreme obesity is rising, more metabolic procedures are performed, and more patients are exposed to the risks of peroperative and postoperative complications [In other types of surgery, such as cardiothoracic and orthopedic surgery, tranexamic acid (TXA) has been proven to be effective in reducing hemorrhage. In these studies, administration of TXA was safe, as no increase in VTE was seen in these patients [The effectiveness of TXA in metabolic surgery has not been investigated in a randomized controlled trial. The aim of the current trial was to investigate if peroperative administration of TXA could reduce the per- and postoperative hemorrhage rates in patients undergoing SG, without increasing the risk of VTE.