Results
T 5:5, loss of consciousness, 05Figure, hypotension, intraoperative adverse
ADVERSE EVENTS
128 patients were included in this study. Data from 128 patients were obtained for statistical analysis (Fig. 
 A fow chart of the current trial
Comparison of the general situation of the two groups of patientsA total of 137 adverse events occurred in 128 patients, of which 44 adverse events occurred in 64 patients in the ciprofol group and 93 adverse events occurred in 64 patients in the propofol group. Among those who had 2 or more adverse events in one person, 11% were in the ciprofol group and 48.5% were in the propofol group. The overall incidence of adverse events was significantly lower in the ciprofol group compared with the propofol group (56.2% vs. 92.2%,P < 0.05). The incidence of hypotension was the highest, accounting for 44.5% of the total adverse events. Those who required intraoperative ephedrine to boost blood pressure were 5 cases in the ciprofol group and 9 cases in the propofol group, of which 2 patients in the propofol group used it twice and the rest used used it once, with no statistically significant difference between the two groups (P > 0.05), as shown in Table 
Incidence of intraoperative adverse eventsThe success rate of induction was 100% in both groups, and the comparison between the two groups was not statistically significant (P > 0.05).The time of loss of consciousness in the ciprofol group was longer than that in the propofol group (1.6 ± 0.4 min vs. 1.4 ± 0.2 min), which was statistically significant (P < 0.05). The time of awakening was not statistically significant in the two groups(P > 0.05).Top-up dose during the operation was not statistically significant in the two groups (P > 0.05), (Table 
Secondary outcomesThe intraoperative blood pressure, heart rate, and BIS trends were similar, with a transient decrease in blood pressure after injection, followed by an increase in blood pressure and tending to stabilize. Compared with T1, SBP、HR were lower at T2 ~ T9 and the difference was statistically significant.The difference between SBP at T 1 and at T 3 ~ T 6 in the ciprofol group was lower than that in the propofol group(P < 0.05).The difference between BIS at T 1 and at T4、T 6 ~ T 8 in the ciprofol group was larger than that in the propofol group(P < 0.05)(Table 
Comparison of intraoperative hemodynamics and anesthesia depthNote: T 1: Before Anesthesia, T 2: before endotracheal intubation, T 3:1 min after endotracheal intubation, T 4: at the beginning of surgery, T 5:5 min after surgery, T 6:10 min after surgery, T 7:15 min after surgery, T 8: At the end of Surgery, T 9: after extubation.Comparison with T1, *P < 0. 05Figure 
Changes in blood pressure, heart rate, and BIS at different time points during the patient’s perioperative period