Baseline clinical characteristics
PD, postoperative cerebral hemorrhage, allergic reaction
ALLERGIC REACTION
The final analysis included 180 patients undergoing heart valve replacement, with 45 patients in each group. In Group C, one patient withdrew from the test because the operation time was > 8 h, and another patient’s relatives chose to terminate the test because of the low cardiac output after the operation; two patients withdrew from Group D because of postoperative cerebral hemorrhage or severe allergic reaction during the operation; and one patient withdrew from Group PD because the operating time was > 8 h. Therefore, 175 patients completed the study and were included in the data analyses (Fig. Patient randomization, follow-up, and analysis