Data collection
bradycardia, seizures, nausea and vomiting, hypotension, hypertension
ADVERSE EFFECTS, HYPERTENSION
The following data were collected for each patient: Age, Body mass index (BMI), and gestational age. Basal blood pressure and heart rate were assessed then monitored continuously and it was recorded at the time of each TCD measurement.TCD of MCA parameters including the mean velocity (MV), the mean end-diastolic velocity (DIAS), and the pulsatility index (PI) as well as the calculated cerebral perfusion pressure (CPP) and MCA velocity were recorded as basal measurements before administration of the study drugs then at post-treatment one and six hours after drug administration.The need for other antihypertensive drugs e.g., nifedipine, nitroglycerine, hydralazine was recorded for each group.The occurrence of seizures in each group was monitored and managed. Also, any adverse effects of the study drugs such as hypotension (A systolic blood pressure of less than 90mmHg or diastolic of less than 60 mmHg), bradycardia (resting heart rate of under 60 beats per minute), persistent hypertension (Patients with persistent blood pressure above the target blood pressure), nausea and vomiting were noted and recorded.