Randomization sequence generation
Patients who met all the inclusion criteria and none of the exclusion criteria were included in the study. Participants were randomly assigned following a 1:1 allocation ratio to either the experimental group (Standard of Care [SoC] + MGVA) or control group (SoC) through computer-generated random sequence numbers. The randomization was performed through the eCRF based on the REDCap platform (Research Electronic Data Capture software, REDCap Consortium).