2.5. Statistical Analysis
To test for the effects of Cerebrolysin across all time points (pre-therapy, post-therapy, and after 90 days), we used a two-way repeated measures analysis of variance (ANOVA) with time and groups as the within-patient factor and the between-patient factor, respectively, when the conditions were fulfilled. Otherwise, a robust two-way repeated measures analysis of variance with time as a group factor was used. The generalized Eta-Squared was used as a measure of effect size, with an interpretation small closer value of 0 and a large closer value of 1.The one-way repeated ANOVA was used when the conditions were fulfilled to test the changes in the outcome measures over time within each group separately. Otherwise, the Friedman test was used. Within ANOVA, multi-comparisons were conducted using a paired The assumption of sphericity was tested by the Mauchly’s test. In cases when the assumption of sphericity has been violated, the Sphericity corrections were used. The Greenhouse–Greisser (GG) and the Huynh–Feldt (HF) were used for adjusting the degrees of freedom from the repeated measures ANOVA. If the GG value was greater than 0.75, the HF value was used.The assumptions related to approximately normally distributed data at each time point were tested using the Shapiro–Wilk test and normal QQ plots.The independent A statistical analysis was conducted in RStudio (version 1.4.1106). The basic level of statistical significance was set at 0.05.