Animal care
C57BL/6 mice were maintained under a 12 h:12 h light:dark cycle (holding room lights on at 06:00 and off at 18:00) at 22 ± 1 °C and 50% humidity. Mice had ad libitum access to standard chow diet (7.5% fat, 75% carbohydrate, and 17.5% protein by energy [RM1 diet; Special Diet Services]) and water. All animal care protocols and procedures were performed in accordance with current regulations and ethical approvals.