Outcomes
Annual rate of change in eGFR calculated separately for the period from
baseline to the final follow-up visit (i.e. “total slope”) and for
the period from 2 months to the final follow-up visit (i.e. “chronic
slope”) were tertiary outcomes in the original protocol, with exploratory
analyses of these outcomes pre-specified. Acute dips in eGFR were calculated as
the difference in eGFR between baseline and the 2 month follow-up visit.