Method
HSP
HSP
We conducted a randomized clinical trial with a cross-over design for the
control group, and a 15-week follow-up period after training. Thirty-six
people with pure HSP were randomized to 5 weeks of (i) gait-adaptability
training (10 hours of C-Mill training—a treadmill equipped with augmented
reality) or (ii) a waiting-list control period followed by 5 weeks
gait-adaptability training. Both groups continued to receive usual care. The
primary outcome was the obstacle subtask of the Emory Functional Ambulation
Profile. Secondary outcome measures consisted of clinical balance and gait
assessments, fall rates, and spatiotemporal gait parameters assessed via 3D
motion analysis.