Primary and Secondary End Points
Angina, SAQ angina, angina
ANGINA AT REST
PCI denotes percutaneous coronary intervention, SAQ denotes Seattle Angina Questionnaire, EQ-5D denotes EuroQOL 5 dimensions, and EQ-VAS denotes EuroQOL visual analogue scale.Treadmill exercise time and stress echocardiography score are presented for the patients who had both pre-randomization and follow-up scores.The Canadian Cardiovascular Society class ranges from 0 to IV where class 0 denotes no angina and class IV denotes angina at rest.SAQ scores range from 0 to 100, with higher scores indicating better health status.European Quality of Life–5 Dimensions (EQ-5D) descriptive system values range from 0-1, and on the EQ-VAS values range from 0 to 100, with higher scores indicating better health status.The derivation of the stress echocardiography score has been previously publishedCalculated as SAQ angina frequency of 100.For all end points, the follow up values are derived from their respective models and a typical patient. A typical patient was taken to be the mean patient at baseline for treadmill exercise time and stress echocardiography score, and the median patient for all other end points.The widths of the confidence intervals have not been adjusted for multiplicity. Thus, the confidence intervals should not be used to reject or not reject treatment effects.