Discussion
KOA, pain
OBESE
This study was the first to assess the effects of a 12-week BFR training program on pain, muscle strength, and physical function among individuals with KOA complicated with MASLD. This study targeted middle-aged and elderly obese patients with a higher incidence of knee OA than other populations and aimed to evaluate the effectiveness of BFR in knee OA rehabilitation. The main findings of this study include: 1) WB training with or without BFR increases knee ROM and muscle strength in patients with KOA comorbid with MASLD; 2) pain reduction afforded by WB with BFR was greater than that of WB training in the short- (4 weeks) but not long-term (12 weeks); 3) WB with BFR improved function in daily living and knee-related quality of life better than WB training alone; 4) and WB and BFR are safe and reliable interventions for individuals with KOA comorbid with MASLD.