Changes in the α-diversity of vaginal microbiota after the intervention
A total of 5,479,608 high-quality sequences were obtained from 87 (Before: n = 45; After: n = 42) sequencing samples. The rarefaction curves of the Shannon diversity (α-diversity analysis of vaginal microbiota before and after the use of the postbiotic gel. Rarefaction curves of In order to study the difference between the two groups of samples, the samples were screened, and the samples that could not be paired were excluded, and a total of 42 pairs of samples were obtained. The chao1, number of observed species, Shannon, and Simpson indexes of the vaginal microbiota of subjects were analyzed, and decreasing trends were observed in all four measured diversity indexes after using the postbiotic gel, though the differences were not statistically significant (