Study setting {9}
Patients are being recruited at 13 academic tertiary care hospitals with high-volume kidney transplant units in Austria, the Czech Republic, France, Germany, the Netherlands and Spain. At each centre, appropriately trained medical staff will be available to provide the necessary standard of care for trial participants and to perform medical care specific to the trial and beyond. The trial sites have a local laboratory or cooperate contractually with external service providers to be able to perform the laboratory diagnostics required for the trial in a qualified manner (Table 