Discontinuation of antidepressants after MBCT
psychiatric
Discontinuation rates at 6-month follow-up were slightly higher in the SPD + MBCT group (44%) than in the SPD group (33%). This difference was smaller than we had hypothesized, which can in part be explained by the SPD group showing a higher discontinuation rate (33%) than we had anticipated (15%). Perhaps this was caused by our selective sample; those who did proceed to the intervention phase of the study were probably motivated to give discontinuation a try. Although the discontinuation rate in the MBCT group (44%) was in line with our a priori expectation (40%), it was at the low end of estimates from a systematic review, in which 40% to 95% of participants were able to discontinue when supported by psychological or psychiatric treatment [