3.7. Post hoc analysis in relation to occupation ratio to 
nasal blockage
Analysis of intestinal flora indicated that the occupation ratio of Changing occupation ratio of In this study, the symptom of nasal blockage was improved by NTM048 12 weeks after the start of trial. The changes of occupation ratio were affected by NTM048 for 16 weeks. The changes of occupation ratio could therefore be directly reflected in improvement of nasal blockage 12 weeks after the start of the trial. Hypothesizing that the occupation ratio was linearly increased in a time-dependent manner, we evaluated the association between improvement of nasal blockage and increasing the occupation ratio of 