Primary analysis
TB
REGRESSION
We report results for the intervention period, comparing the intervention clinics with control clinics. For all analyses, we assumed that those with an Ultra trace result were negative for The primary analysis compared the mean number of TB patients diagnosed per month per clinic between study arms during the intervention period only, using both Ultra and liquid culture results. Unadjusted analyses used the In a sensitivity analysis, we applied Poisson regression—excluding each intervention arm clinic’s first month of intervention data to account for a possible initial learning period and a regression excluding the 2 GP clinics that had only 4 months of activity before being replaced. A sensitivity test was applied to this primary analysis but using clinic-based TB count data. Finally, although not protocol specified, we report the primary outcome modeling the results as though the Ultra were the only assay used, as it is unlikely that laboratory capacity to conduct large numbers of mycobacterial cultures would be feasible. Additionaly, we also report results assuming trace results were included as positive Ultra result.To assess the impact of the study fieldworker, we also report a dose–response test, using the Poisson regression, within the intervention clinics to evaluate if the number of days that study fieldworkers were present in the clinic per study month was associated with the number of TB cases diagnosed.