Comparison of biological equivalent doses of radiotherapy schemes
Abbreviations: BED: Biologically effective dose; IC-CRT: Intermediate course chemoradiotherapy; LC-CRT: Long-course chemoradiotherapy; SC-RT: Short-course radiotherapy.In the LC-CRT group, 45 Gy/25 fr was prescribed and the PTV included a 1 cm margin in excess of the GTV, adding another 5.4 Gy/3 fr, for a total dose of 50.4 Gy/28 fr. Three-dimensional conformal RT and intensity-modulated RT were used to perform the planning. The patients were treated using a Siemens ONCOR (Siemens Healthineers, Erlangen, Germany) or a Truebeam STx linear accelerator system (TrueBeam STx; Varian Medical Systems, Palo Alto, CA, USA/Siemens Healthineers, Erlangen, Germany) and underwent daily digital portal imaging.Concurrent chronomodulated capecitabine (Brunch regimen: morning and noon) 1650 mg/m