Treatment effects on proportion of patients with clinical levels of symptoms
fatigue, anxiety, cognitive impairments, insomnia, depression
Generalized linear mixed models revealed significant time effects on the proportion of patients having a clinical anxiety (HADS‐A) and FCR (FCRI) score. Post hoc comparisons showed that the proportion of patients with clinical anxiety was significantly greater at V0 (30.6%) as compared to V3 (12.6%) and V5 (16.1%) and greater at V2 (25.4%) than V3 (12.6%). In addition, they revealed proportions of clinically significant FCR which were significantly higher at V0 (42.2%) than V3 (26.3%), V4 (25.9%), and V5 (23.6%). No significant time effect was found on proportions of patients with clinical depression (HADS‐D, PHQ‐9), insomnia (ISI), fatigue (FSI), cognitive impairments (FACT‐Cog), and no significant group‐by‐time interaction was obtained on any variable.