4. Discussion
obesity
OBESITY
Results of this trial showed significant reductions in obesity indices and total and visceral fat without any significant change in serum leptin and adiponectin levels. Although energy and macronutrient intakes decreased in both groups, greater reductions were observed in the control group than in the intervention group (In the present study, although there were slight reductions in mean concentrations of leptin and adiponectin as well as an increase in leptin to adiponectin ratio in both groups, intergroup differences were not statistically significant after the trial, even after adjusting for the confounding factors (In the present study, lack of using placebo, studying only female subjects, and relatively short duration of the trial are considered as limitations. However, to the best of our knowledge, this trial is considered as one of the limited human studies to have examine the effect of HCA extract derived from 