Univariate and Multivariable Logistic Regression Analysis of Trial Positivity
REGRESSION
Abbreviations: OR, odds ratio; PEP, primary end point.Trial positivity was defined by whether the trial met the prespecified goal for significance at final analysis or publication based on reported trial goals (including the PEP) at the time of publication. Univariate and multivariable logistic regression was performed to assess whether PEP changes, accrual goals, and funding sources were associated with trial positivity.