Effect of secretin on BAT and brain GU metabolic crosstalk
Full-volume analysis of brain GU levels revealed no statistically significant difference between the placebo and secretin conditions. In contrast, there was a significant difference between conditions while controlling for BAT GU (Fig. fMRI paradigm for the response inhibition task. Participants were instructed to press the button on the go and rare go signals and refrain from pressing the button on the no go signalsFurther analysis revealed that BAT GU was a significant predictor for GU in the caudate and cingulate area in the secretin condition (Fig. Secretin modulated the BAT-brain metabolic crosstalk (