Antiseptic efficacy
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The colony morphology was very diverse for all samples. Colonies exhibiting a morphology specific for For analysis of the antiseptic efficacy, data from both groups were combined for each rinse (n = 20 for every rinse and time point).Granudacyn® resulted in a lg- reduction of 0.94 ± 0.42 and 0.94 ± 0.56 (cheek right/ left) and 0.89 ± 0.45 (saliva) 1 min after rinsing. This effect was slightly increasing up to 30 min (Table The lg-reduction for Octenidol® md was about 2.29 ± 0.91 (cheek right), 2.26 ± 0.66 (cheek left) and 2.11 ± 0.66 in the saliva. The effect was consistent (cheek) up to 15 min and afterwards slightly decreasing (Table Both test products were significantly effective in reducing cfu for up to 60 min after rinsing.
Mean lg-reduction for 20 test persons using Granudacyn® mouthwash, Octenidol® md mouthwash and Ringer- solution in comparison to the control. *p < 0.05, **p < 0.01, ***p < 0.001There was no statistically significant difference in cfu (cheeks) between the negative control (ringer solution) and Octenidol® md (p = 0.12) and between Octenidol® md and Granudacyn® (p = 0.20) before rinsing (F = 6.817, p = 0.0016, rOne minute after rinsing until 60 min after rinsing, there were statistically significant differences between the negative control and Granudacyn (p < 0.0001) or Octenidol® md (p < 0.0001) as well as between Granudacyn® and Octenidol® md (p < 0.0001).For saliva samples, no statistically significant results were obtained for the baseline between the negative control, Granudacyn® and Octenidol® md (F = 1.231, p = 0.2997, r