2.3. Randomisation Procedure
cancer type
The randomisation sequence was generated using the PLAN procedure of SAS statistical software (Enterprise Guide version 4.3 or higher). The permuted block randomisation was stratified for cancer type and treatment (chemotherapy, concurrent chemoradiotherapy or immunotherapy). The allocation ratio was 2:1 for the IG and the CG, respectively. An independent statistician generated the allocation sequence and decided the block sizes, which were random. Details about sequence generation, block size or sizes and whether the block size(s) were fixed or random were unknown to the investigator and research site staff who were responsible for enrolling eligible subjects into the study and assigning them to their given randomisation numbers.