Discussion
The introduction of new strategies like the use of shorter course regimen still does not address the operational limitations of DOT, including the unguaranteed accuracy of patient adherence information. In as much as MEMS technology may not be absolutely accurate in estimating patient adherence since opening the device may not imply drug ingestion, it does provide a patient-centred solution, relieving the burden on patients to meet an obligation of frequent clinic visits and maintaining patient autonomy [