Conclusions
discolored peristomal skin
SKIN CONDITION
This study presents the psychometric validation of the OST 2.0 instrument. The evidence provided support that OST 2.0 is reliable and valid for assessing severity of PSCs. Unlike the OST, this new tool enables close monitoring and captures subjects with PSC even in the absence of discolored peristomal skin. The Decision Tree score and PIB score both have great potential as a primary endpoint in clinical investigations. However, the meaningful change estimates should be interpreted with caution due to the sample size and the SD intervals of the estimates. Collectively, the OST 2.0 instrument provides a standardized, objective, sensitive, and easy-to-use approach for closely assessing changes in peristomal skin conditions over time, which can capture both visual and non-visual symptoms of PSC.