Effect of SQ-LNS
We conducted a complete case intention-to-treat analysis. To test hypothesis 1, for each of the 8 outcomes described earlier (SDQ-Child, SDQ-Parent, SDQ-Teacher, BPM-P, MFQ, SCARED, EATQ-P, and CEMS), we examined the difference between the intervention (SQ-LNS) and control (non-LNS) groups using multivariate analysis of covariance (MANCOVA) models for outcomes with multiple subscales and ANCOVA models for single scale outcomes. Our primary comparison of interest was the SQ-LNS group with the control group (IFA and MMN groups combined). However, we also compared the IFA and MMN groups to confirm that it was appropriate to combine them, as demonstrated by no significant difference at Three versions of each model were assessed. The first model was adjusted for child age at follow-up only. The second model was additionally adjusted for child sex, developmental assessment data collector, and any of the following baseline variables that were significantly associated (To test hypotheses 2 and 3, we added to models 1 and 3 the EC-HOME score at 5 y, then the interaction between the intervention group and EC-HOME scores. As reported previously, EC-HOME scores did not differ between the intervention groups [