Study population
unresectable HCC, HCC
LIVER DISEASE, ONCOLOGY, LIVER CANCER
Eligible patients were aged at least 18 years and had advanced HCC, defined as unresectable locally advanced or metastatic HCC, confirmed by histology or clinical presentation according to the American Association for the Study of Liver Diseases criteria.The historical control cohort was non‐interventional and retrospective, comprising patients with unresectable HCC identified from the Hospital Sírio‐Libanês Oncology Department electronic medical records using the keyword “liver cancer.” Patients had to have a diagnosis of advanced HCC after loco‐regional therapy, have been recommended for systemic therapy, or be receiving best supportive care.