Primary Outcome: 3-Month Dose of Methadone
We report findings for all 131 participants in an intention-to-treat analysis. Fifty-four individuals were randomized to TAU, 77 to C-OLP. Starting methadone doses for both groups ranged from 10 to 40 mg (mode = 25 mg). There were no statistically significant differences between the groups in their mean (SD) dose at day 90: 83.1 (25.1) mg for group TAU (n = 33) and 79.4 (19.6) mg for group C-OLP (n = 60) (