Statistical analyses
SECONDARY
Data were statistically analyzed with SPSS IBM version 27 and graphs were created in GraphPad Prism version 9.3.1. The primary and secondary outcomes were analyzed by means of a non-parametric Wilcoxon signed-rank test. Explorative outcomes were analysed by means of a non-parametric Wilcoxon signed-rank test in the case of paired data or by linear mixed model analyses for data acquired over time. Linear mixed model analyses with random intercept were performed to analyze changes over time as compared to baseline upon clenbuterol versus placebo administration. For this, time points were normalized for baseline values and a linear mixed model analyses was performed on the timepoints 