The switch of TDF to TAF elicited changes regarding bone quality
From baseline to 24-week after randomization we observed a significant increase in bone tissue quality measured by microindentation only in the TAF arm [81.6 (79-83) to 86 (80-88)] (mean percentage change +5.1%); p=0.041, whereas BMSi values remained stable in the TDF group 82.35 (76-85) to 82 (73.5-83) (mean percentage change -0.05%); p=0.812 (
