Safety assessments
gastrointestinal (GI) perforations, non-melanoma skin cancer, infections, malignancies, VTE, NMSC, venous thromboembolism, herpes zoster, deaths, GI perforations
GI PERFORATION, OPPORTUNISTIC INFECTIONS, ADVERSE EVENTS, EVENTS, INFECTIONS, MALIGNANCIES, OIS, HERPES ZOSTER
Safety assessments included: adverse events (AEs) of special interest (serious infections, opportunistic infections [OIs], and herpes zoster [HZ; non-serious and serious]); gastrointestinal (GI) perforations; malignancies (excluding non-melanoma skin cancer [NMSC]); NMSC; major adverse cardiovascular events (MACE); venous thromboembolism (VTE); infections (all); and deaths. OIs, GI perforations, malignancies (including NMSC), and MACE were reviewed by independent adjudication committees.