Secondary outcomes
digits recall backwards
SECONDARY
For the backwards digit span, there was a significant dose-by-time interaction at 800 mg CBD (0.76, 95%CIs: 0.01, 1.54), but not at 400 mg CBD (0.41, 95%CIs: − 0.34, 1.25). The change in performance was 0.30 (95%CIs: 0.02, 0.58) in the 800 mg group; 0.13, (95%CIs: − 0.14, 0.42) in the 400 mg group, and − 0.08 (95%CIs: − 0.35, 0.1 in the placebo group; see Fig. Group means of number of digits recall backwards, by treatment group at baseline and week 4. Error bars represent bootstrapped 95% confidence intervalsFor all other secondary outcomes (SSRT, TMT A, TMT B-A, forwards digit span, letter fluency, category fluency and drug fluency), there was no significant dose-by-time interaction at 400 mg or 800 mg CBD. There was also no main effect of dose for any secondary outcome.For immediate prose recall, TMT A and category fluency, there was a significant main effect of time. See supplementary materials for details of all analyses of secondary outcomes.