Subgroup analyses
quadriceps femoris muscle, quadriceps femoris muscle CSA, desaturation, quadriceps femoris muscle CSA.This
The impact of supplemental oxygen and exercise-induced peripheral desaturation led to different adaptations of total quadriceps femoris CSA between the respective subgroups (Table Impact of exercise training on quadriceps femoris muscle CSA.This table shows that, although patients’ total CSA (in centimeters squared) of their quadriceps femoris muscle has increased during the exercise training intervention, the impact was found statistically significant different when subgroups were compared with a one-way analysis of variance (*Subgroup comparisons of exercise capacity and CSA. The changes (Δ) of peak work rate (in watts) and quadriceps femoris muscle CSA (in centimeters squared) are presented in panels a and b, respectively. Functional and structural adaptation showed both similar training responses in the different subgroups.Impact of supplemental oxygen on training adaptations in desaturating patients. The impact of supplemental oxygen on patients with exercise-induced peripheral desaturation significantly affected the training adaptations on quadriceps femoris CSA (ΔCSA [in centimeters squared]) related to the respective peak work rate (Δ [in watts]).Correlations of structural with functional parameters of exercise capacity.This table provides an overview on how the changes of total CSA (quadriceps femoris muscle) during the training intervention are correlated with the impact on functional capacity, aerobic capacity, muscle strength, and exercise tolerance. Pearson’s correlation coefficient is provided for all variables.***