Randomization and treatment allocation
Participants were randomly assigned in a 1:1 ratio either to a standard 6-month regimen group or to 4-month PRS regimen group using a random number generator. Patients and physicians were unaware of the allocated treatment until the patient had been formally entered into the trial but were not blinded afterward. Standard 6-month regimen (2HRZE/4HR) referred to the WHO treatment guidelines [