Ethical considerations
Ethical approval for the Saving and Empowering Young Lives in Europe (SEYLE) study was sought at each site of the study. For the Irish site, this was granted by the Clinical Research Ethics Committee of the Cork Teaching Hospitals. Three arms of the study (Control, Question-Persuade-Refer & Youth Aware of Mental Health) had opt-out consent and the other (Professional Screening) had opt-in consent. For safety during the RCT, students across all treatment arms who indicated acute suicide risk during baseline or follow-up assessments were immediately contacted by the SEYLE team and invited for a subsequent interview and referral to care.