1. Introduction
OA, osteoarthritis, pain, KOA, Knee osteoarthritis, disability
OSTEOARTHRITIS, KNEE OSTEOARTHRITIS, DISEASE
Knee osteoarthritis (KOA) is a prevalent joint condition associated with aging that causes pain, loss of function, and disability, as well as a decline in quality of life, with a significant societal and economic cost.Disease prevalence varies by geographical location. In the Middle East and North Africa, 24.6 million cases (95% UI: 22.0–27.3 million) of osteoarthritis (OA), with an age-standardized point prevalence of 5342.8 per 100,000 (95% UI: 4815.9–5907.8) were recorded, which was 9.3% higher than in 1990 (95% UI: 8.1–10.5%).The most common type of OA is KOA.Cryotherapy, a non-pharmaceutical treatment, has been widely used to treat some rheumatic joint conditions.