Ethics approval and consent to participate
This study has been registered on the International Clinical Trials Registry Platform (ClinicalTrials.gov, NCT04120155). This study was approved by the ethics committees/institution review boards of three institutions (Fujian Medical Union Hospital, Fuqing City Hospital, and Sanming Second Hospital). All participants provided written informed consent. This study followed the Consolidated Standards of Reporting Trials (CONSORT) reporting guideline for randomized clinical trials.