Outcome measurements
metabolic syndrome, Sex‐specific metabolic syndrome, TG, fasting blood glucose
METABOLIC SYNDROME, SECONDARY, BATEMAN
The primary outcome of interest in this analysis was adherence to the CR intervention. Energy expenditure was measured by doubly labeled water, an objective biomarker of energy intake (Wong et al., Cardiometabolic risk factor measurements were assessed as secondary outcomes of interest and included C‐reactive protein (CRP), high‐density lipoprotein (HDL), low‐density lipoprotein (LDL), triglycerides, blood pressure, fasting glucose and insulin levels, and a metabolic syndrome score (MSS). Sex‐specific metabolic syndrome scores were computed in the CALERIE trial using mean BP (MBP = [2 × diastolic BP + systolic BP] / 3), HDL, triglycerides (TG), waist circumference (WC), fasting blood glucose (FBG), and standard deviation (SD), as detailed previously (Bateman et al., 