Discussion
T2D
In the current research, we combined information from experimental and observational studies to investigate the association between a composite biomarker score of adherence to the Mediterranean diet and incident T2D. The key findings were that a biomarker score derived within the MedLey RCT had a high discriminatory performance between the Mediterranean and habitual diet arms, and that when this biomarker score was applied to the pan-European EPIC-InterAct Study, there was an inverse association with incident T2D. The 95% prediction interval for this association did not include the null, suggesting that our finding would be expected to be replicated in similar populations [