Serology results
Thirty-three percent of the patients (35/106) were seronegative after two doses. At 4 weeks following the receipt of the booster vaccine, 57% (20/35) of these patients seroconverted and had a detectable antibody response as demonstrated by anti-S antibody testing, meeting the primary endpoint of our study. The median titer at baseline (after primary vaccination) for the entire cohort was 212.1 AU/mL (IQR 50–2873 AU/mL) and the median titer at 4 weeks (after third dose of the vaccine) for the entire cohort was 9997 AU/mL (IQR 880.7–47,063 AU/mL) (