Author contributions
J.Z. and J.F. contributed to conceptualization. J.Z., J.F., and G.S. contributed to methodology. G.S., X.H., D.W., G.Y., Y.J., Y.C., N.G., H.S., X.H., X.M., S.Q., X.Y., Q.G., C.L., Y.X., Y.H., Z.R., and J.S. contributed to collection of samples and clinical data. G.S., X.H., and F.L. contributed to formal data analysis. G.S., X.H., J.Z., H.S., J.Z., and J.F. contributed to paper writing. Each author has read and approved the paper. All authors are eligible for the data of the study and had the right to decide the submission and publication.