Patients
infection, primary osteoarthritis, trauma
INFLAMMATORY ARTHRITIS, INFECTION, SECONDARY, SOFT TISSUE INFECTION, BLEEDING DIATHESIS
Patients were recruited from outpatient clinics of rheumatology and orthopedics department at Phramongkutklao Hospital, Bangkok, and an outpatient clinic of orthopedics at Srinagarind Hospital, Khon Kaen, from 1 August 2019 to 28 February 2021.Eligible patients were 50 years of age or older who were diagnosed with primary osteoarthritis of knee (either monoliteral or bilateral) according to the American College of Rheumatology (ACR) clinical classification criteria [Exclusion criteria were patients who had contraindication for IA injection such as overlying skin and soft tissue infection, uncontrolled bleeding diathesis, had IA glucocorticoid injection in the past 3 months, had IA hyaluronic acid in the past 6 months, patients with secondary OA due to inflammatory arthritis, trauma or infection or history of knee replacement in the same joint and planning for knee surgery within 3 months.