Introduction
INTELLiVENT–adaptive support ventilation (ASV) is a closed–loop ventilation mode that uses pressure–controlled or pressure support ventilation depending on patients’ activity. Continuous pulse oximetry and capnography are used for adjustments of positive end–expiratory pressure (PEEP) and fraction of inspired oxygen (FiOWith INTELLiVENT–ASV, either sidestream or mainstream capnography can be used, although these techniques have never been compared directly [Thus far, clinical studies of INTELLiVENT–ASV only tested its safety and efficacy when using mainstream capnography. Sidestream capnography could serve as an attractive alternative for mainstream capnography, in certain settings and in several patient categories. The differences in the accuracies of the two techniques, however, could affect the performance of the closed–loop ventilation mode [