Statistical Analysis
SECONDARY
Sample size and power calculations were carried out using PASS (Power Analysis and Sample Size) software (version 13.0.8; NCSS, LLC) based on the primary outcome NDI [The noninferiority tests on primary and secondary outcomes were performed in R (version 3.6.0; R Foundation for Statistical Computing), using the package Demographic characteristics are presented as mean and SD or median and IQR. For binary baseline data, The proportion of responders to treatment was determined in each group, with clinically important improvements in NDI (≥7% reduction) [