Sequence effect improved during neural closed-loop DBS in one participant

Example of Wrist Flexion Extension (WFE) (A) OFF therapy, (B) open-loop clinical stimulation, (C). neural closed-loop stimulation. Peaks from each WFE cycle indicated by black dots with the fitted exponential curve overlaid.NclDBS improved the sequence effect in 8 out of the 10 NclDBS conditions across various delay periods between the two hands (Neural closed-loop parameters