Data Collection and Variables
’ cancer, cardiotoxic, cancer, diabetes
CANCER, DYSLIPIDEMIA, PCP, HYPERTENSION, DIABETES
At the time of consent, we asked all participants to list their PCPs over the 2 years preceding trial enrollment. We then requested PCP outpatient clinic medical records over this time frame, including clinician notes, medication lists, laboratory results, and imaging reports for all participants. Through manual record review, we ascertained the number of PCP and specialist visits, as well as documentation of the testing for, diagnosis of, and treatment of hypertension, dyslipidemia, and diabetes. We determined whether there was documentation of participants’ cancer history, cardiotoxic treatment exposures (ie, anthracycline-based chemotherapy, radiation therapy affecting the heart), need for late-effects screening, and the presence of any SCP, the latter of which we defined as a note or document providing a summary of a participant’s past cancer treatment combined with an evidence-based follow-up plan. We also documented whether more in-depth cardiac testing (eg, electrocardiogram [ECG], echocardiogram, or other imaging) was performed or planned.On trial enrollment, we asked participants to self-report their personal medical history to allow for comparisons with CCSS research records and PCP medical record documentation. Specifically, participants were asked whether they had previously received radiation or cardiotoxic chemotherapy; had undergone various medical and cardiovascular testing in the preceding 2 years (ie, echocardiogram, blood pressure measurement, diabetes screening or testing, lipid screening or testing); or were using medications for hypertension, diabetes, or dyslipidemia. Participants’ historical treatment exposures were derived from CCSS research data, which were based on an abstraction of each survivor’s original cancer treatment records. Participant demographics were obtained from CCSS research data. Participants self-reported race and ethnicity to the CCSS study team. Race was categorized as American Indian or Alaska Native, Asian, Black, Pacific Islander, White, or unknown. Ethnicity was categorized as Hispanic or Latino, not Hispanic or Latino, or unknown. Other race and ethnicity categories were self-reported as other and nonspecified. Race and ethnicity were assessed to examine the study cohort and consider the generalizability of its findings to other populations. CCSS research data were considered the criterion standard in comparisons between different reporting methods.