Study design and oversight
INTELLiSTREAM was an investigator–initiated and investigator–sponsored, single-center, single–blinded, non–inferiority, randomized clinical trial comparing postoperative closed–loop ventilation using sidestream versus mainstream capnography. The study was performed at the Amsterdam University Medical Centers, location ‘AMC’, Amsterdam, the Netherlands. The trial was approved by the local Institutional Review Board (METC 2019_222; Chair prof. dr. J.A. Swinkels; date of ethical approval march 6