2.6. Statistical Analysis
To determine if any of the previously described overlap statistics can be used as biomarkers of survival, we analyzed each one using Kaplan-Meier curves for OS and PFS [Excluding information about spatial volume change, OS and PFS Kaplan-Meier curves are also generated for subjects with Cho/NAA ≥ 2x volume growth and reduction. The percentage of volume change can be tested as an additional biomarker with OS and PFS Kaplan-Meier curves stratified by median volume change.