Association of high cortisol and clinical outcomes, stratified by admission CRP levels
inflammation
INFLAMMATION
To better understand the influence of inflammation and cortisol levels, a subgroup analysis stratified by high CRP (≥ 100 mg/l) and low CRP (< 100 mg/l) admission levels was performed (Supplementary Table 2). Most results remained unchanged. However, increases in short- and long-term risk of mortality was more pronounced in the high CRP group, while reduction of caloric and protein intake was more pronounced in the low CRP group.Kaplan-Meier Survival Analysis (Fig. 
Survival probability over 30 days stratified by cortisol quartiles and CRP levels Abbreviation: CRP, C-reactive protein; No, number adjusted for age, sex, NRS, main diagnosis, comorbidities and trial interventionlow cortisol: cortisol ≤ 723 nmol/l, high cortisol: > 723 nmol/llow CRP: CRP < 100 mg/l, high CRP: ≥100 mg/l