Conclusions
CRSwNP, LKS, NPS
RECURRENCE
The addition of postoperative systemic steroids after primary FESS did not show a benefit over topical steroid nasal spray alone with respect to NPS, SNQOL, LKS, GQOL, sinonasal symptoms, smell scores, and biomarkers over a short-term follow-up of up to 9 months and a long-term follow-up of up to 24 months in CRSwNP patients. Simultaneously, the addition of postoperative systemic steroids had no impact on recurrence rates and the need for revision surgery. Functional endoscopic surgery did, however, show a strong effect on all outcome measures, which remained relatively stable up to the endpoint at 2 years. Future studies with a larger sample size have to confirm those results.