Clinical Significance
ADHD
NERVOUS SYSTEM DISORDERS
Methylphenidate and amphetamines have shown high efficacy in treating ADHD in children and adolescents; however, approximately 40% of patients with ADHD respond to only one of these drugs, indicating the need for additional treatment options, including multiple formulations. Although transdermal therapies have numerous advantages in the treatment of nervous system disorders, only one FDA-approved transdermal treatment (methylphenidate) for ADHD in children and adolescents is currently available.