GMTs and seroconversion rates of neutralizing antibodies against the prototype strain
To assess the dynamic changes of neutralizing antibodies before and after immunization, blood samples from participants in the CoronaVac group were detected at seven time points. Four days after the first dose of CoronaVac, GMTs and seroconversion rates (SCR) of neutralizing antibodies against the prototype strain of SARS-CoV-2 showed no differences compared to those on day 0 in both the younger (18-59 years) (pDynamic changes in neutralizing antibody titers against prototype strain of SARS-CoV-2 at different time points. Participants received two doses of CoronaVac on Day 0 and Day 28. Neutralizing antibody titers at seven time points (Day 0, 4, 14, 28, 32, 42, 56) were measured. The neutralizing antibodies increased in a similar pattern after the second dose of CoronaVac. Neutralizing GMTs and seroconversion rates did not show significant differences between day 28 (before the second vaccination) and day 32 (4 days after the second dose) in each age subgroup (pTo further demonstrate the dynamic changes of the neutralizing antibody titers, reverse cumulative distribution plots were drawn (