Results
metabolic syndrome, Anxiety, inflammation
METABOLIC SYNDROME, INFLAMMATION
Among the 66 participants with metabolic syndrome who enrolled in the clinical trial, 62 participants completed the trial (n = 33 in the propolis and n = 29 in the placebo, groups). During the intervention, four subjects from the placebo group were excluded due to move (n = 1), gastrointestinal side effects (n = 1), and not willing to continue (n = 2) (Fig. Flow chart of study participants.Table General characteristic of study participants in propolis and placebo groups at baseline.Values are presented as mean ± standard deviation and frequencies (percentages). Abbreviation: BMI, body max index; WC, waist circumference. P-values were derived from the independent-sample t test for quantitative variables and Chi-square test for qualitative variables between the two groups. Dietary intake and physical activity of study participants before and after of the intervention.Values are presented as mean ± standard deviation or median [interquartile range]. Abbreviation: SFA, saturated fatty acids; MUFA, monounsaturated fatty acids; PUFA, polyunsaturated fatty acids. *P-value were derived from Mann–Whitney U test. As reported in Table The effects of propolis supplementation on anthropometric indices, blood pressure, inflammation status, glycemic parameters and lipid profiles in two groups.Values are presented as mean ± standard deviation and median [interquartile range]. Abbreviation: FBS, fasting blood sugar; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HOMA-IR, homeostasis model of assessment-insulin resistance; CRP, C- reactive protein; TC, total cholesterol; SBD, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index. * P-value were derived from Mann-Whiney U test. The effects of propolis supplementation on mood status and quality of life before and after of intervention are reported in Table The effects of propolis supplementation on mood status and quality of life before and after of intervention.Values are presented as mean ± standard deviation. Abbreviations: Dass-21, the 21-Item Depression Anxiety and Stress Scale; SF-36; the 36-Item Short Form Health Survey. * P-value were derived from ANCOVA test with baseline values as the covariate. 