Strengths and Limitations
This study benefited from several strengths. We used fMRI as an established method to detect arousal by mapping activated brain areasRegarding limitations, the population of this randomized clinical trial was limited to right-handed heterosexual men to standardize the sexual stimuli used during the fMRI tasks. Whether our findings are generalizable to a wider population remains to be determined in broader cohorts (for instance, including different sexual orientations, broader age groups, and left-handed patients). Moreover, variations in subjective arousal from the sexual stimuli may have been encountered; to mitigate this, an independent focus group was convened to select the most arousing videos. The short videos did not include audio. However, it is established that men generally respond to visual sexual stimuli, whereas women require the addition of auditory and olfactory cues for arousal.