References
NAFLD, NAFLD Fibrosis
NONALCOHOLIC FATTY LIVER DISEASE, INSULIN RESISTANCE
Change in serum FGF21 comparing exercise training to standard clinical care. Serum FGF21 was reduced by 22% (−243 ng/mL) following exercise training, whereas standard clinical care patients had an increase of 34% (+88 ng/mL).Correlation between change in serum FGF21 and VOBaseline comparisons between Exercise and Standard Clinical Care participants.BMI = body mass index; GLP = glucagon-like peptide; HOMA-IR = homeostatic model assessment for insulin resistance; MRI = magnetic resonance imaging; NAFLD = nonalcoholic fatty liver disease; NAS = NAFLD Activity Score; PDFF = proton density fat fraction; VOOutcome measures: Non-invasive tests.ALT = alanine aminotransferase; CK = cytokeratin; FGF = fibroblast growth factor, FIB-4 = fibrosis-4 index; MRI = magnetic resonance imaging; NAFLD = nonalcoholic fatty liver disease; NFS = NAFLD Fibrosis Score; PAI = plasminogen activator inhibitor, PDFF = proton density fat fraction. Reported as geometric mean (95% CI) unless indicated.Outcome measures: Anthropometry and body composition, fitness, biochemistry and lipids.ALT = alanine aminotransferase; AST = aspartate aminotransferase, BMI = body mass index; HDL = high-density lipoprotein; HOMA-IR = homeostatic model assessment of insulin resistance; LDL = low-density lipoprotein; VAT = visceral adipose tissue; VO