Cardiovascular Health Outcomes at the End of 8 Weeks and Main Effect Model Estimates for Primary and Secondary Outcome Analyses
SECONDARY
Abbreviations: HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TMAO, trimethylamine SI conversion factors: To convert HDL-C and LDL-C to mmol/L, multiply by 0.0259; triglycerides to mmol/L, multiply by 0.0113; glucose to mmol/L, multiply by 0.0555; insulin to pmol/L, multiply by 6.945; vitamin BAll laboratory data are fasting values from plasma (lipids, glucose, insulin, and vitamin BMeans (SEMs) are unadjusted.Primary and secondary outcomes fixed effects for diet and time (baseline as reference) and an interaction effect for diet (omnivore as reference) by time, a random effect for twin pair to account for the correlation between identical twins (ie, random intercept allowed intercept to vary for each twin pair), and a random effect for participant to account for correlation of longitudinal data.