Eligibility
Barrett’s esophagus, GERD, hernia, chronic kidney disease
COAGULATION DISORDERS, ESOPHAGEAL ULCERATIONS, GERD, STRICTURES, EROSIVE ESOPHAGITIS, CIRRHOSIS OF THE LIVER

Inclusion criteria were patients aged > 18 years who had undergone POEM (by posterior myotomy, Eckardt score < 3), and had ≥ 6 months of proton pump inhibitor (PPI)-dependent GERD (GERD questionnaire [GERDQ] score ≥ 8), abnormal 24-hour pH impedance off PPIs (AET > 6 %), and willingness to cooperate with postoperative follow-up assessment. Patients were excluded if any of the following applied: previously failed POEM, sigmoid esophagus, hiatus hernia > 2 cm, grade D erosive esophagitis, esophageal ulcerations and strictures, Barrett’s esophagus, cirrhosis of the liver, chronic kidney disease, pregnancy or plans for pregnancy in the next 6 months, plans to travel during the study period, receipt of psychotropic drugs (anxiolytics, antidepressants), coagulation disorders, prior gastric or esophageal surgery, body mass index < 18.5 kg/m
