Outcome measurement
RCC, NRS
SECONDARY, RCC
The primary outcome was reintubation within 72 h after extubation. The secondary outcomes were reintubation within 7 days of extubation, changes in physiological parameters and arterial blood gas analysis results, time to liberation from NRS, duration of respiratory support, length of RCC and hospital stay, ventilator-free days at 28-day and 90-day mortality. Successful liberation from NRS was defined as the time point at which a patient was alive and free of NRS (HFNC or NIPPV) for more than 48 h.