3.2. Efficacy, Pharmacokinetic and Pharmacodynamic Evaluations
The mean onset of castration for the SC regimens ranged from 1.10 days (120 mg SC for 2 days) to 1.77 days (90 mg for 2 days), while it was 2.4 days with 90 mg IM administration. The mean duration of castration across the studies ranged from 32.45 days (range: 0–6 weeks for 120 mg SC for 2 consecutive days) to 68.95 days (range 5–21 weeks for 180 mg SC for 3 consecutive days) (The mean pharmacokinetic (PK) results (teverelix DP concentrations (ng/mL) +SEM) for the studies are presented in 