Background
neutropenia, 3-methylglutaconic acid, BTHS, Barth syndrome, skeletal muscle weakness
NEUTROPENIA, RARE CARDIOMYOPATHY, GROWTH RETARDATION, GENETIC DISEASE, BARTH SYNDROME
Barth syndrome (BTHS) is a rare X-linked genetic disease which occurs in approximately 1 in 1,000,000 male live births. Typical features of BTHS are cardiomyopathy, skeletal muscle weakness, growth retardation, neutropenia, and increased urinary excretion of 3-methylglutaconic acid [Elamipretide is a synthetic lipophilic tetrapeptide with high cell permeability [The widespread availability of real-time physiological data on various health metrics such as heart rate (HR) and respiratory rate (RR) presents a significant opportunity for data mining and machine learning to answer important clinical questions [