Author’s contributions
K.W., M.S, F.F. and R.O. designed the work, acquired data and played important role in interpreting the results. C.R., H.B. and C.B. contributed in laboratory work, trial design and interpreting the results as well as in revising the manuscript. S.F. played an important role in the interpretation of the results and revised the manuscript. Z.B.-H. and M.R. contributed in acquiring data as well as in interpreting the results and revising the manuscript. R.E., M.F., R.B., M.B., C.F.S., D.E. and M.G. acquired data and designed the work as well as revised the manuscript. All authors approved the final version and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.