2.5. Statistics
Statistical analyses were performed using the IBM SPSS statistical software package (version 23, IBM, Armonk, NY, USA). Sample size estimation was based on an effect size of 0.69 and an SD of 1.5 as described previously [For the following analysis, the data of the whole cohort were analyzed. This was feasible because in the original study there was no influence of protein intake on the study groups. Thus, the relevant outcome variables were not different.