Volcano plot showing differentially abundant serum metabolites at 6 months versus baseline for thymectomy + prednisone group.
Gray dots represent metabolites and lipids that were not significantly altered in thymectomy + prednisone group at 6 months versus baseline. Purple dots represent metabolites with a fold change greater than 2-fold (cutoff), orange dots represent metabolites and lipids with a significant p value (p < 0.05) and green dots indicates those metabolites and lipids with both a significant fold change and p-value. Differences were tested using the non-parametric Mann Whitney U test and FDR correcting for multiple testing with Benjamini-Hochberg procedure two-sided. Individual p-values for each metabolite and lipid are found in (DOCX)Click here for additional data file.