5. Conclusions
inflammation, impaired obese, obese
INFLAMMATION, OBESE, CHRONIC DISEASES
Overall, results from this study demonstrated that DSC intervention seemed to protect obese subjects from worsened obesity-related conditions such as increases in BW, BMI, and HR observed in the placebo group. Moreover, DSC consumption may attenuate inflammation and cardio-metabolic dysregulation in obese adults through the modulation of IFNγ and blood pressure. Interestingly, these outcomes seemed to be beneficial in obese subjects with a high BMI. Moreover, significant changes in anti-inflammatory IL-10 detected in the placebo group suggest an attempt to restore homeostasis to counterbalance obesity-related inflammation, while no changes were detected in the cherry group. Results from this study demonstrated the benefits of DSC for blood pressure and inflammation and suggest the intake of DSC as a dietary approach to enhance health in obese individuals who are at risk of developing chronic diseases. Findings of this study remain to be confirmed in larger intervention studies with metabolically impaired obese subjects.