Study setting
The ANRS 12249 TasP trial was a cluster randomised trial implemented between March 2012 and June 2016 by the Africa Health Research Institute (AHRI) to evaluate the effectiveness of immediate ART on HIV incidence. The trial was implemented in the Hlabisa sub-district, northern KwaZulu-Natal, South Africa. Hlabisa is a largely rural area, with scattered homesteads, an estimated HIV prevalence of 30.5% [