Statistical Analysis
AKI, postreperfusion syndrome, DCD liver
REGRESSION, SECONDARY, SURGICAL COMPLICATIONS
A sample size of 58 patients was needed to detect a 50% reduction in peak AST, as determined with a 2-sided, 2-sample pooled Results for the primary end point are reported for the full analysis set and a per protocol set. For secondary outcomes, the results for the per protocol set are given.For the primary end point, a linear regression model was used on log-transformed values with treatment group as a factor, yielding a ratio of geometric means with 95% CIs. In a sensitivity analysis, MELD score and CIT were added as confounders. The primary end point analysis was repeated in the full analysis set with exclusion of patients who received a DCD liver. Odds ratios and 95% CIs are given for the comparison of frequencies of EAD, AKI, postreperfusion syndrome, and severe surgical complications. Mann-Whitney U tests with the Hodges-Lehmann estimator as effect size were performed to compare acute cellular rejection Banff