Pathologic Complete Response
INV
Twenty-two (45.8%) of 48 patients in the evaluable population achieved pCR (95% CI, 32.0%-60.6%) by both ICR and investigator assessment. Among patients in the ITT population, the pCR rate was 49.2% (30/61) (95% CI, 36.7%-61.6%) and 47.5% (29/61) (95% CI, 35.0%-60.1%) by ICR and investigator assessments, respectively (Pathologic complete response. Abbreviations: CI, confidence interval; ICR, independent central review; INV, investigator; ITT, intent-to-treat; pCR, pathologic complete response. 