Study population
malignancy
We conducted a retrospective, single-center study approved by the institutional review board. All clinical CTLS exams performed from January 1Follow-up scans used to evaluate ILA progression were designated by annual screening rounds with T0 representing the initial scan and T4 representing the 5th round of screening. Each round of screening ended with a negative scan (Lung-RADS® 1 or 2) and the next round of screening was determined by the first screening exam at least 11 months (335 days) after that negative scan. Individuals found to have a malignancy were censored at the time of first positive scan. Those with T4 screening scans were scored for progression (n = 652).