Conclusions
A novel reactive drug-based intervention targeting household members and surrounding neighbors of a recently reported index patient in Thailand was shown to be acceptable by those receiving RDA and feasible to implement by the public health staff and VHVs included in this qualitative study. To maximize uptake of RDA, regular education and sensitization campaigns in collaboration with village leaders on the purpose and rationale of RDA will be critical. To alleviate safety concerns and increase participant safety, a rigorous pharmacovigilance monitoring program will be important. To accelerate uptake of RDA, trust between public health staff and VHVs and the communities they serve must continue to be strengthened to ensure acceptance of the intervention.