Author contributions
Y.L.Y., C.F.L. and T.H.Y. conceived and designed the study protocol; Y.L.Y., C.F.L. and T.H.Y. enrolled participants and carried out the experiment; Y.L.Y., Y.W.C. and A.J. performed data analysis; Y.L.Y., Y.W.C., A.J., T.H.Y. and C.F.L. wrote the manuscript draft, A.J. and C.F.L edited and revised the final manuscript; All authors reviewed the manuscript; All authors read and approved the final manuscript.