Study design
T2DM
This study is a parallel randomized clinical trial that involved individuals with T2DM of both sex that performed different aerobic training protocols, two times per week for eight weeks. The study was performed at the Hospital of the Federal University of Goias (Goiania, Brazil), approved by the relevant Human Research Ethics Committee (Protocol No. 2,667,732, CAAE No. 54522016.6.0000.5083) and registered on the Brazilian clinical trial records (ID: RBR-4RJGC3). All participants gave written informed consent in accordance with the Declaration of Helsinki. Participants were assigned by randomization to one of three groups using a specialized website (Before and after the training period, participants were evaluated for anthropometric measures, resting BP, cardiopulmonary exercise test and blood markers. Anthropometric measures included weight and height for calculating body mass index (BMI), as well as waist and hip circumference. Weight was measured using a digital scale (BC 553, TanitaAll experimental procedures were carried out in the morning, with relative humidity between 40 and 60%, and temperature between 22 and 24°C, according to American College of Sports Medicine guidelines (ACSM) (