Characteristics of the study participants and clinical assessments
arrhythmia, Stroke, intracerebral hemorrhage, Diabetes mellitus, Hyperlipidemia, Heart disease, hemorrhage, hypoglycemic, Hypertension, depressive symptoms, atrial fibrillation, cerebral infarction
ARRHYTHMIA, STROKE, INTRACEREBRAL HEMORRHAGE, EVENT, DIABETES MELLITUS, HYPERLIPIDEMIA, HEART DISEASE, HEMORRHAGE, SUBARACHNOID HEMORRHAGE, HYPERTENSION, ATRIAL FIBRILLATION, CEREBRAL INFARCTION
As reported in our previous study [Treatment history of depressive symptoms was defined as currently receiving treatment or having received treatment in the past for depressive symptoms. Hypertension was defined as a prescription for antihypertensive medication(s) or a measured systolic blood pressure > 140 mmHg and diastolic blood pressure > 90 mmHg. Diabetes mellitus was defined as a prescription of insulin or oral hypoglycemic medications, a high plasma glucose level (≥ 126 mg/dL), or a high glycated hemoglobin level (≥ 6.5%) after eight hours of fasting. Hyperlipidemia was defined as a prescription for lipid-lowering medications or high levels of total cholesterol (≥ 200 mg/dL), low-density lipoprotein cholesterol (≥ 130 mg/dL), and triglycerides (≥ 150 mg/dL) and low levels of high-density lipoprotein cholesterol (< 40 mg/dL). Heart disease was defined as a history of an acute coronary event or arrhythmia including atrial fibrillation or use of heart-related drugs. Stroke was defined as a history of cerebral infarction or hemorrhage such as intracerebral hemorrhage and subarachnoid hemorrhage.