Patients
Tumors, cancer, tumor
DISEASE, CANCER, TUMOR, TUMORS
HLA-A*02-eligible and MAGE-A4-eligible patients were enrolled from a multicenter, screening protocol study (Eligibility criteria included age ≥18 years to ≤75 years; histologically confirmed cancer diagnosis; positivity for at least one HLA-A*02 inclusion allele; MAGE-A4 RNA or protein expression in one or more tumor samples; and measurable disease according to Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 before LD chemotherapy (see Sixty-three patients were deemed eligible and were enrolled into the intent-to-treat (ITT) population; 60 patients underwent leukapheresis; and 38 patients were treated with afami-cel (modified ITT (mITT) population) (Fig. 