Characteristics of the Patient Population at Baseline
obesity, Phlebotomy difficulties, phlebotomy difficulties, pulmonary artery systolic pressure, heart failure
OBESITY, HEART FAILURE, HIGH TRIGLYCERIDES
Abbreviations: ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blocker; BMI, body mass index, calculated as weight in kilograms divided by height in meters squared; BNP, B-type natriuretic peptide; bpm, beats per minute; DOAC, direct-acting oral anticoagulant; eGFR estimated glomerular filtration rate; H2FPEF, heart failure with preserved ejection fraction; Hb, hemoglobin; HbA1c, glycated hemoglobin; LDL, low-density lipoprotein; NTproBNP, N-terminal pro B-type natriuretic peptide.Missing 1 in the sacubitril/valsartan group because of data recording error.Missing 10 in the sacubitril/valsartan group because of phlebotomy difficulties (3) and laboratory errors (7) and 4 in the valsartan group because of laboratory errors. Phlebotomy difficulties included venous access and volume obtained.Missing 13 in the sacubitril/valsartan group because of phlebotomy difficulties (3), laboratory errors (7), and high triglycerides (3) and 8 in the valsartan group because of laboratory errors (4) and high triglycerides (4).Missing 10 in the sacubitril/valsartan group because of phlebotomy difficulties (3) and laboratory errors (7) and 4 in the valsartan group because of laboratory errors.Missing 3 in the sacubitril/valsartan group because of phlebotomy difficulties (2) and a laboratory error (1) and 7 in the valsartan group because of laboratory errors.Missing 2 in the sacubitril/valsartan group because of phlebotomy difficulties and 1 in the valsartan group because of laboratory error.Missing 2 in the sacubitril/valsartan group because of phlebotomy difficulties.Missing 1 in the valsartan group because of laboratory error (NTproBNP obtained).Missing 4 in the sacubitril/valsartan group and 3 in the valsartan group because of laboratory errors (3 in each group) and 1 phlebotomy difficulty in the sacubitril/valsartan group. BNP was obtained in all 7 patients.The H2FPEF score comprises 1 point for each of the following: older than 60 years, treatment with 2 or more antihypertensive drugs, E/e′ greater than 9, and pulmonary artery systolic pressure greater than 35 mm Hg; 2 points for obesity (BMI >30 kg/m