Discussion
hypertension, postoperative nausea and vomiting, P.
ADVERSE EVENTS, CEREBROVASCULAR ACCIDENTS, DISEASE, HYPERTENSION, DISEASES
In this study, we demonstrated that the MAP, HR, CO, and CI at T1, T2, T3, and T4 were significantly higher in Group R than P, while SVR was significantly lower in Group R than P. The incidence of total adverse events was 73% in patients in Group P but only 20% in patients in Group R.Elderly patients’ health is often complicated by a variety of diseases, of which hypertension is the most common. Their tolerance to anesthesia and surgery is lower than that of younger patients. Severe hemodynamic fluctuations can easily induce cerebrovascular accidents. Tracheal intubation during anesthetic induction is a severely noxious stimulus and can have a severe impact on patients’ hemodynamics. Maintaining stable hemodynamics of elderly patients during induction and improving the blood perfusion of the heart, brain, kidney, and other important organs can improve the disease outcome and prognosis of elderly patients [As a commonly used anesthetic in the clinical setting, propofol has the advantages of rapid onset, short duration of action, no accumulation in the body, and minimal postoperative nausea and vomiting. Propofol is widely used in the induction and maintenance of anesthesia. It exerts its sedative and hypnotic effects through interaction with gamma-aminobutyric acid receptors and has certain cardiovascular inhibitory effects that can lead to a decrease in blood pressure, CO, and HR [Remimazolam is a new benzodiazepine drug that has the advantages of rapid recovery and metabolism, no drug accumulation, independence from liver and kidney metabolism, and few side effects [