Strengths and weaknesses of the study
A study strength is our comprehensive use of open and closed questions to appropriately address the study aim and objectives, with open-ended questions allowing respondents to expand on answers provided. However, only one researcher conducted the content analysis of open-ended questions which might have led to coding errors.Although our response rate (average 36%) could be considered low, it was on par with response rates observed in other studies where trialists have been surveyed [A further limitation was that our email was not delivered to all identified corresponding authors for example where researchers were on leave or had moved to a new role as suggested by automated email responses. This meant that some identified corresponding authors did not get the opportunity to participate.