Intervention and measurements
BLOOD
An open intravenous access was established in the patient’s upper extremity in the waiting area. After entering the endoscopy room, the patient was placed in the supine position on the operation bed. Blood pressure, electrocardiogram, and blood oxygen saturation were monitored. The doses of drugs were calculated based on the actual body weight, using specifications based on those of a previous study [Remimazolam (201114AK, Hengrui, Jiangsu, China) was diluted to 0.5 mg/mL, while propofol (2011171, Guorui, Sichuan, China) was diluted to 1, 2, and 10 mg/mL with normal saline (NS). To minimize discomfort, all patients received 0.1 μg/kg of sufentanil (01A10011, Renfu, Sichuan, China) intravenously over 10 s. The cannula was washed with 5 mL of NS. After 90 s, remimazolam and propofol were administered over 10 s according to the group-specific dose. The two drugs were administered at 20-s intervals. After each dose, the cannula was rinsed with 5 mL of NS, and the observation began after 1 min. Hypnosis was achieved when the eyelash reflex was lost [The EDThe patients were divided into group A (remimazolam), group B (propofol), group C (0.25ED