Outcomes
bradycardia, CRBD, nausea, vomiting, agitation, hypotension, Depression, shivering, Hypotension, NRS, dry mouth
ADVERSE EFFECTS, SECONDARY, DRY MOUTH, RESPIRATORY DEPRESSION
The primary outcome was the incidence of CRBD at 0 h after the surgery (on admission to the PACU). The secondary outcomes included incidence of CRBD at 1, 2, and 6 h postsurgery, the severity of CRBD at 0, 1, 2, and 6 h postsurgery. Other outcomes included remifentanil requirement during surgery, sufentanil requirement within 24 h postsurgery, the NRS score at 48 h after the surgery, magnesium-related side effects and rescue medication (morphine) requirement.Magnesium-related adverse effects, such as hypotension, bradycardia, respiratory depression, agitation, shivering, dry mouth, nausea and vomiting, were assessed intraoperatively and at 6 h postoperatively. Hypotension and bradycardia were defined as decrease of mean arterial pressure and heart rate by 20% of baseline value. Depression, agitation, shivering, dry mouth, nausea and vomiting were reported by the staff or patient in a yes or no question.