Statistical Analysis
throat
A study participant was considered positive for SARS-CoV-2 if the pathogen was detected by RT-PCR (reference standard) in the nasal, throat, or both specimens. The reference standard was then used to calculate the sensitivity, specificity, positive predictive value, and negative predictive value of the rapid antigen testing of different specimens (eAppendix 5 in We performed a post hoc analysis to explore the robustness of our findings when including invalid or missing rapid antigen tests as negative using an intention-to-treat approach.