Author Contributions
K.T., E.O., K.Y. (Kenichi Yanagimoto) and K.Y. (Kaori Yokoi) conceptualized and designed the study; K.T., Y.T. and H.U. performed the experiments; E.O., H.U. and Y.T. analyzed the data; K.T., H.U., Y.T. and E.O. interpreted the results of the experiments; K.T. prepared the Figures and Tables; E.O. drafted the article; E.O., K.T., Y.T. and K.Y. (Kenichi Yanagimoto) edited and revised the manuscript. All the contributors approved the final version of the article. All authors have read and agreed to the published version of the manuscript.