Author Contributions
A.A.-Á., M.E.S. Acquisition, statistical and data analysis or interpretation of data. M.E.S. Had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. A.A.-Á., I.P.-T. and M.E.S. Conceptualization and methodology. I.P.-T., R.C.-S., L.M.-P., S.C.-A., R.M.-V., J.F.-G. and M.E.N.-M. Methodology, patient care and sample handling. Acquisition, data analysis, or interpretation of data. L.M.-P. Graphical abstract. V.G.-L. Revised and structured the manuscript. All authors have read and agreed to the published version of the manuscript.