MATERIALS AND METHODS
This study was a randomized controlled trial in free-living conditions. The study was conducted at the Turku PET Centre, Turku, Finland, between April 2017 and March 2020 according to good clinical practice and the Declaration of Helsinki. The participants gave their informed consent before entering the study. The study was approved by the Ethics Committee of the Hospital District of Southwestern Finland (16/1810/2017). The study is registered at 