Research plan and outcomes
T2DM
SECONDARY, INSULIN RESISTANCE
This study used FMT as an auxiliary method to compare the therapeutic effects of solely metformin, solely FMT and FMT combined with metformin onT2DM patients. Eight T2DM patients received FMT plus metformin treatment, 9 patients underwent FMT alone and 12 patients received solely metformin treatment. The primary research objective was to evaluate the efficacy of FMT in assisting the metformin treatment in T2DM adult patients from the aspects of blood sugar control and insulin resistance. The secondary research objective was to observe the influence of FMT on the bacterial engraftment from donor microbiota during baseline inspection and week 4 intervention. We classified microbiota species identified in the recipients into four types and mainly focused on the donor-associated species as previously defined (