Young women had the highest aldosterone levels
Raw data of the aldosterone concentrations in the groups of younger and older men and women are shown in Table Raw data of aldosterone concentrations in male and female study participants during pre- and post-stimulation.Shown are means ± standard deviations for the younger and older cohort.Distribution of serum aldosterone concentrations by age and sex. Shown are boxplots representing the distribution of serum aldosterone concentrations in pg/ml separately for males and females of the younger and older cohort. The darker-colored boxes pool 50% of all the data points, while together with the light-colored boxes, 75% of all the data points are depicted. The black lines depict the median of the respective distribution plots, while the black dots represent the respective mean. Significant differences are shown between male and females within a cohort based on the Yeo-Johnson transformed data set (linear mixed models). Results from a linear mixed model using the parameters body-mass index (BMI), sex, age and the interaction term of sex and age on Yeo-Johnson-transformed aldosterone concentrations irrespective of stimulation conditions (tVNS, sham).Depicted are the estimated β-coefficients, including their corresponding 95% confidence interval (95%CI). The following dummy coding was applied: sex (female = 0, male = 1), age (younger = 0, older = 1).