Author Contributions
P.M. and P.P.S. had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis; Conceptualization: P.M. and P.P.S.; Investigation: E.M., E.T., M.R., A.B., P.B., M.B. (Mattia Bellan), G.B., M.B. (Massimo Bertoletti), G.F.C., L.M.C., U.C., D.C. (Davide Comolli), D.C. (Donato Colangelo), M.C., A.C., D.D., L.D.M., V.D., F.G., A.G., L.G., G.G., R.L., A.L., R.M. (Roberto Manzoni), V.M., B.M., R.M. (Rosalba Minisini), M.M., A.N., E.O., R.P., A.P., L.R., E.R., D.S., M.S., N.T., S.T., G.T., A.T., P.V., R.V., V.V., E.Z., N.Z., P.M. and P.P.S.; Writing—original draft: E.M., M.R., P.M., and P.P.S.; Writing—review and editing: all authors; Formal analysis: D.A. and P.P.S.; Project administration: E.M., E.T., M.R., A.B., P.B., M.B. (Mattia Bellan), G.B., M.B. (Massimo Bertoletti), G.F.C., L.M.C., U.C., D.C. (Donato Colangelo), D.C. (Davide Comolli), M.C., A.C., D.D., L.D.M., V.D., F.G., A.G., L.G., G.G., R.L., A.L., R.M. (Roberto Manzoni), V.M., B.M., R.M. (Rosalba Minisini), M.M., A.N., E.O., R.P., A.P., L.R., E.R., D.S., M.S., N.T., S.T., G.T., A.T., P.V., V.V., E.Z., N.Z., P.M. and P.P.S.; Supervision: G.C.A., M.B. (Mattia Bellan), L.M.C., F.D.C., G.P., M.P., P.M. and P.P.S.; Final approval of the version to be published: all authors; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved: all authors. E.M., E.T. and M.R. contributed equally to this work. P.M. and P.P.S. contributed equally to this work. All authors have read and agreed to the published version of the manuscript.