Background
malaria, Malaria
MALARIA, HELMINTH INFECTIONS, MALARIA, SCHISTOSOMIASIS
Malaria is a leading cause of the high rate of child mortality that persists in sub-Saharan Africa (SSA) [As a prelude to developing an integrated model for the control and elimination of co-infection with The establishment of an effective programme for delivering Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SPAQ) to more than 40 million children resident in the Sahel and sub-Sahel areas, where malaria transmission is highly seasonal, and where helminth infections are prevalent, provides an opportunity for combining SMC with mass drug administration (MDA) programmes for prevention of schistosomiasis and STH. However, before a recommendation for combining MDA with anthelminthic drugs (praziquantel and albendazole) for schistosomiasis and STH with SMC drugs can be made, it is important to show that this would be safe and well tolerated by pre-school and school-age children and that the incidence of side effects would not be significantly higher in children who received the combined SMC and anthelminthic drugs than in those who received SMC drugs alone.The findings of an intervention study (ClinicalTrials.gov NCT05354258) [