Aims/hypothesis
hyperglycaemia, LGA, hyperinsulinism, weight gain
PRE-ECLAMPSIA, DIABETES IN PREGNANCY, HYPERINSULINISM, DIABETES IN PREGNANCY, NEONATAL HYPOGLYCAEMIA, HYPERGLYCAEMIA, COMPLICATIONS
Type 1 diabetes in pregnancy is associated with suboptimal pregnancy outcomes, attributed to maternal hyperglycaemia and offspring hyperinsulinism (quantifiable by cord blood C-peptide). We assessed metabolomic patterns associated with risk factors (maternal hyperglycaemia, diet, BMI, weight gain) and perinatal complications (pre-eclampsia, large for gestational age [LGA], neonatal hypoglycaemia, hyperinsulinism) in the Continuous Glucose Monitoring in Women with Type 1 Diabetes in Pregnancy Trial (CONCEPTT).