Participants
miotic
LENS
In all, 66 consecutive adult subjects (at least 20 years of age) were recruited. After obtaining informed consent, demographics, medical/ocular history, and present ocular medications were recorded. Eyes were excluded if they had any previous intraocular or corneal surgery (except laser refractive surgery), used a rigid contact lens within 1 week or soft contact lens within 24 hours, were currently on mydriatic and/or miotic medications, or were incapable of fixating at the internal fixation light or opening the eye sufficient to image a full image area. When both eyes of the participant were eligible, one eye was randomly selected by coin flip.Study eyes underwent a series of imaging by three CASIA SS-1000 devices and three Pentacam devices. These devices were placed in three separate rooms. In each room, one CASIA SS-1000 and one Pentacam were installed and one examiner was assigned to operate the devices. Three images were taken by each of six devices. A computer-generated, randomization schedule was used to determine the order of the rooms/examiners and the order of the devices (CASIA SS-1000 vs. Pentacam) in a room. The exam procedure took approximately 1 h for imaging a total of 18 images in each eye. With this design, the device effect and examiner effect were confounded, and is called the [device+examiner] effect throughout the rest of this paper.