Introduction
blood loss, fractures, trauma
BLOOD LOSS
In adults, approximately 2% of all fractures are tibial shaft fractures. The most common cause of these fractures is high-energy trauma (traffic trauma, fall from a height, crushing injury, etc.) [Tranexamic acid (TXA), which is a synthetic antifibrinolytic agent that inhibits the production of plasminogen by competitively binding to its lysine-binding sites to enhance the effectiveness of the patient’s own haemostatic mechanisms, has been used for many years to reduce blood loss in orthopaedic surgery [