Itch measurement
pruritus, itching, itch
We evaluated the itch severity in 2 ways. First, itch severity was measured with visual analogue scale (VAS), which is one of the most frequently used methods for pruritus assessment [Second, the intensities of daytime and nighttime itching were measured with the Xie-kawashima itch scale [The summary change of mean larger Xie-kawashima itch scale between latter seven-day pre-observation and latter seven-day treatment period.Abbreviations: LS means: least-squares means; CI: confidence interval.