Introduction
Ulcerative colitis, UC, Dysbiosis of gut microbiota, chronic intestinal inflammation, autoimmune disease
AUTOIMMUNE DISEASE, REMISSION, DISEASES, ULCERATIVE COLITIS
Ulcerative colitis (UC) is a prototypical autoimmune disease with chronic intestinal inflammation (Dysbiosis of gut microbiota, including fungi, is associated with many diseases (Fecal microbiota transplantation (FMT) is a strategy to reconstruct gut microbiota by administering a new microbiome from healthy individuals to patients (In this study, we used shotgun metagenomics to analyze the longitudinal dynamic change of gut fungal communities in active UC patients after capsulized FMT treatment. We demonstrated significant alterations in the fungal community in patients who received capsulized FMT and identified specific fungi associated with clinical remission after FMT.