Main Exposure
Antidepressant prescription records were obtained from the NHIRD based on the Anatomical Therapeutic Chemical (ATC) code N06A. Antidepressant use was indicated by the presence of 1 or more prescriptions for antidepressants. We divided antidepressants into 3 classes: (1) SSRIs (ATC code N06AB), (2) SNRIs (ATC codes N06AX16 and N06AX21), and (3) TCAs (ATC code AN06AA). Individuals in each antidepressant subgroup were not mutually exclusive. In addition to these 3 major classes of antidepressants, the users of remaining atypical antidepressants such as bupropion, mirtazapine, and trazodone were categorized as other antidepressants in 