Gut microbiota
One patient in the TRF group did not submit fecal sample at baseline. There was no significant difference in the chao1 index for gut microbiota alpha diversity between the TRF group (Δ = 16.51 ± 64.94) and the CD group (Δ = -6.84 ± 41.62) (Based on LDA selection, at baseline, from phylum to genus level, there were 4 differential intestinal flora (LAD >2, Gut microbiota analysis between groups. TRF, time-restricted feeding; Linear discriminant analysis (LDA) effect size (LEfSe) bar plot; After the intervention, there were 13 different intestinal flora (LAD >2, 