Conclusion
hemorrhage, VTE
HEMORRHAGE, MINOR, POSTOPERATIVE HEMORRHAGE, COMPLICATIONS
This study could not demonstrate a statistically significant difference in use of hemostatic clips and in major complications after peroperative administration of TXA. However, TXA seems to have a positive effect on postoperative hemoglobin, heart rate, minor complications due to hemorrhage and LOS in patients undergoing SG, without increasing VTE rate, and other side effects. A limitation of this study is the primary endpoint, reduction in hemostatic clips. To investigate whether TXA can reduce postoperative hemorrhages, we are conducting a larger randomized controlled trial with postoperative interventions as primary outcome.