Limitation
edema
EDEMA, INFLAMMATION
There still existed some limitations in this study. First, the present study was designed to be a single-center study with a small sample size. Multicenter trials with more les are still needed. Second, only the thickness and cross-sectional area of skeletal muscle were measured, and there may be measurement errors in patients with edema and local inflammation. At the same time, it should be emphasized that it is still difficult to accurately evaluate the influence of ventilation mode on diaphragm thickness change. Continuous positive airway pressure (CPAP) was adjusted whenever possible during ultrasound measurements to minimize the influence of breathing patterns on diaphragmatic measurements.