5. Conclusions
inflammation, psoriasis
PATHOLOGY, INFLAMMATION, SKIN CONDITION, PSORIASIS
In conclusion, SXRG84 ingestion has the potential to improve a subset of inflammatory skin conditions, potentially through the reduction of pro-inflammatory cytokines. However, the effect was not seen across all participants, and further work is required to determine the optimal dose, the duration of the trial and the specific skin conditions that may receive a benefit from such treatment. Collectively, these results indicate that there are differences in the microbiome profiles of people with skin conditions (less yoghurt was consumed in those with a skin condition), and that inflammation markers and skin conditions can be improved in some cases following treatment with SXRG84. Tying these four variables of gut microbiome, yoghurt consumption, skin condition and inflammation status together into causal or response relationships requires a larger cohort analysis of consistent skin pathology. Two supplementary case studies indicate the potential benefits in those with PPK and psoriasis, and warrant further investigation.