Measurement of AGEs
LENS
AGEs were measured on the middle finger using an AGE sensor RQ-1201 J (Sharp Life Science, Kobe, Japan), according to the manufacturer’s instructions. Excitation light from the light source through the lens illuminates the skin surface of the fingertip inserted into the sensor. The emission spectrum reflected from the skin is detected as the accumulation of AGEs in the skin. The value of AGEs obtained with this device has been reported to correlate with the blood levels of methylglyoxal-derived hydroimidazolone-1, a major AGE in proteins