Statistical analysis
Via SAS 9.2 software, all statistical analyses were conducted using a one-sided 0.05 hypothesis test, with 95% confidence interval. Unless otherwise stated, measurement data were statistically described as mean ± standard deviation or median (minimum and maximum). Counting data were statistically described by frequency (percentage). The Kaplan–Meier curve was used to estimate median OS and PFS. The statistical hypotheses of this study are as follows: H0 = 12, H1 = 19, α = 0.1, and β = 0.2. According to the dropout rate of 10%, the final sample size was 36 cases.