Statistical analysis
Student’s t-test, 1-way ANOVA, and 2-way ANOVA with Bonferroni post-test analysis were performed where indicated. The number of samples chosen for each comparison was determined based on past similar experiments or by performing pilot experiments to assess the expected magnitude of differences. The number of experiments performed is indicated in the figure legends. Biological assays were performed in triplicate, with separate donors before statistical analysis was performed.