Surgical outcomes
PULMONARY METASTASES, OSTEOSARCOMA, METASTATIC DISEASE
Of 61 patients with OST who underwent PM, the 5‐year EFS and OS were 17% (95% CI: 8.9%–27.9%) and 71% (95% CI: 56.9%–81.8%), respectively (Figure (A) EFS and OS of 61 patients with OST who underwent PM. (B) EFS for localized versus metastatic disease at diagnosis. (C) OS for localized and metastatic disease at diagnosis. (D) EFS for good histologic response and poor histologic response. (E) OS for good histologic response and poor histologic response. EFS, event‐free survival; OS, overall survival; OST, osteosarcoma; PM, pulmonary metastasectomy.Of 24 patients with metastatic OST at diagnosis, 21 patients underwent PM during primary treatment; nine (43%) had thoracotomy, six (28.5%) had thoracoscopy and six (28.5%) had CTT. The initial surgical approach to PM had no statistically significant bearing on survival outcomes (EFS (A) EFS from initial diagnosis for patients with unilateral and bilateral pulmonary metastases at diagnosis. (B) OS for patients with unilateral and bilateral pulmonary metastases at diagnosis. (C). EFS from diagnosis with surgical approaches to initial pulmonary metastasectomy. (D). OS for surgical approaches to initial pulmonary metastases. EFS, event‐free survival; OS, overall survival.Forty‐three ((A) EFS from first relapse for surgical approaches and first pulmonary relapse or progression. (B) OS for surgical approaches to first pulmonary relapse or progression. EFS, event‐free survival; OS, overall survival.Nineteen of the 21 patients with pulmonary metastases at initial diagnosis who underwent PM had reported surgical morbidities (Table Post op morbidities initial resection (
Abbreviation: CTT, combined thoracoscopy with thoracotomy.Of the 43 patients that suffered a first pulmonary relapse/progression and underwent metastasectomy, 40 had morbidities recorded (Table Post Op morbidities first relapse resection (
Abbreviations: CTT, combined thoracoscopy with thoracotomy; OST, osteosarcoma.