Statistical analysis
yellow fever
YELLOW FEVER, RUBELLA, MEASLES
For sample size calculations, we estimated that at least 95% of the children receiving the vaccines sequentially would seroconvert to measles, rubella, and yellow fever [We assessed if seroconversion following co-administration was non-inferior to seroconversion following the administration of individual vaccines as either the first or second vaccine in a series separated by four weeks. We also assessed whether seroconversion following administration as the second vaccine in the series was non-inferior to seroconversion following administration as the first vaccine. Non-inferiority was assessed by comparing the lower bound of the 90% Farrington-Manning confidence interval (CI) for the difference in seroconversion to the non-inferiority margin of -5%. We assessed the pairwise differences in the distribution of antibody concentrations/titers with Wilcoxon rank-sum tests, using a significance level of 0.05. Since all hypotheses were described Analyses are presented for two populations: The 