Results
Asthenia, asthenia, nausea, flatulence, diarrhea, vomiting, Flatulence, hypoglycemia
HYPOGLYCEMIA, BLOOD, REGRESSION
A total of 504 patients were screened; 188 completed all three follow-ups. Table 
Baseline characteristics of the study population

Not Reported = Missing dataBD-Twice a day; OD-Once a day; TDS-Thrice a day
(The patients’ QoL was significantly improved (p < 0.01), presented in Table 
Serial changes in quality of life from baseline to the last follow-up visitThe Wilcoxon Signed Ranks test is applied to observe the mean change in QoL from baseline to follow-up (Non-parametric data). *p < 0.05 is considered statistically significant. Z based on positive ranks
Serial changes in body weight, blood pressure, FPG, and HbA1c from baseline to the last follow-up visitSBP-Systolic Blood Pressure; DBP-Diastolic Blood Pressure; HbA1c-Glycated Hemoglobin; FPG-Fasting Plasma Glucose; SD-Standard Deviation; LL-Lower Limit; UL-Upper LimitPaired Sample T-test is applied to observe the mean change in study variables from baseline to follow-up (for parametric data). *p < 0.05 is considered statistically significantThe HbA1c levels were 7 to 9% in 105 by the 3rd follow-up visit. Only 6 patients had an HbA1c level > 9%, and 76 cases had an HbA1c level < 7% by the 3rd follow-up. Minor AEs were observed, including abdominal discomfort 3.8% (n = 9), nausea 3.4% (n = 8), indigestion 3.4% (n = 8), flatulence 2.9% (n = 7), asthenia 2.5% (n = 6), diarrhea 2.5% (n = 6), hypoglycemia 1.7% (n = 4) and vomiting 0.8% (n = 2).Table 
Linear Regression Model to estimate predictors of QoL (last follow-up visit)Unstandardized Coefficients (B); Standard Error-SE; Standardized Coefficient-Beta (β); Confidence Interval (CI); Lower Boundary (LB); Upper Boundary (UB)$At last follow-up visitR2 = 0.265, Adj R2 = 0.146, F(16, 99) = 2.231, *p < 0.05 is considered significantNausea, Vomiting, Flatulence, and Asthenia are constants or have missing correlations; they were deleted from the analysisNo significant difference in DQoL, FPG, and HbA1c levels was observed for the smoking status (p = 0.404; p = 0.780 and p = 0.288, respectively). Similarly, quality of life and HbA1c levels were comparable among male and female patients (p = 0.163 and p = 0.290); only fasting blood glucose varied between genders (p = 0.020).