Introduction
thyroid carcinoma, tumor, TC, cancer, tumor aggressiveness, PTC
THYROID CARCINOMA, TUMOR, RECURRENCE, DIFFERENTIATED THYROID CARCINOMA, PAPILLARY THYROID CARCINOMA, CANCER, THYROID
Papillary thyroid carcinoma (PTC) is the most common subtype of thyroid carcinoma (TC), and patients with PTC generally have a favorable prognosis (The 2015 American Thyroid Association (ATA) guidelines proposed risk stratification for recurrence based on molecular markers, which is currently the most effective tool for estimating the possibility of recurrence of differentiated thyroid carcinomas, including PTC (As the largest cancer center in South China, our hospital is responsible for receiving referred non–initial treatment patients with tumor relapse or insufficient resection scale in previous treatments. In this subset of patients, we collected initial clinicopathological information that was found to be incomplete, making it challenging to predict recurrence. However, non-initial treatment may be associated with increased tumor aggressiveness, advanced tumor stage, and higher recurrence rates (This study aimed to explore the potential risk factors for recurrence in both initial and non–initial treatment patients. Our study also constructed a nomogram of recurrence to assess risk and provide clinicians with a convenient and practical tool for more accurate patient management.