4. Discussion
dyspnea, cognitive impairment, Dyspnea, reduced muscle force, breathlessness, lung stiffness
DISEASE
In our study, we investigated breathlessness in long-post-COVID-19 patients with mild cognitive impairment during exercise with and without using a VR system. In our analyses, dyspnea was associated with exercise type, body composition parameters, handgrip strength, and WAI score. Dyspnea was recorded to be lower during exercise with VR than during exercise without VR.Previous studies have reported that the perception of breathlessness is related to disease severity, reduced chemosensitivity, age, sex, and reduced muscle force. In addition, psychological factors also play a role in breathlessness perception, and fear of hospitalization and loneliness may also contribute to breathlessness (Previous studies have shown that exercise with a VR system is interesting and enjoyable (Our study included patients who had been previously hospitalized for COVID-19 and had low oxygen saturation. The low PaOThe unpleasantness of dyspnea is related to the activation of the limbic system, right anterior insula, and amygdala (Moreover, breathlessness parallels the loss of elasticity in lung tissue, while lung stiffness also affects a patient's ability to expel CO