Conclusions
delirium, colorectal cancer, tachycardia, postoperative pain
EVENTS, COLORECTAL CANCER, INTRAOPERATIVE HYPERTENSION
In elderly patients undergoing laparoscopic colorectal cancer surgery under general anesthesia, SPI-guided remifentanil consumption was significantly higher than that of conventional analgesia with lower intraoperative hypertension and tachycardia events, and a lower incidence of delirium in the PACU. Nevertheless, perioperative changes in NK cell activity and IL-6, did not show a significant difference between the two groups. Therefore, we suggest that in the elderly undergoing laparoscopic colorectal cancer surgery, SPI-guided analgesia may provide appropriate analgesia with reduced intraoperative hypertension and tachycardia and improve postoperative outcomes, including postoperative pain and delirium in the PACU.