Safety End Points
ADVERSE EVENTS
The safety and tolerability profile of inclisiran was measured by adverse events (AEs), serious AEs, and clinical laboratory values. In addition, an anti-inclisiran antibody analysis was performed. AEs were assessed from baseline to each assessment time up to day 720. Data captured during part 1 (up to day 180) were presented by the part 1 treatment group (inclisiran or placebo), whereas data captured during part 2 (after day 180 up to day 720) were presented by the part 2 treatment group (inclisiran–inclisiran or placebo–inclisiran).