Measurements
bradycardia, tachycardia, Pain, postoperative nausea and vomiting, Hypoxemia, pain, hypoxemia, non-delirium, Delirium, hypotension, NRS
ADVERSE EVENT, HYPERTENSION, POSTOPERATIVE COMPLICATIONS
Demographic characters such as age, gender, body mass index (BMI) and education level were recorded. The preoperative education level, history of operation, preoperative albumin level, surgical type, surgical duration, anesthesia duration, intraoperative liquid volume, perioperative blood transfusion, ICU admission, the hours in the ICU and length of stay in hospital after surgery were recorded.Delirium assessment [Pain was assessed at 8 a.m. on postoperative day 1, day 2, day 3 by NRS (Numeric Rating Scale) (The numbers 0–10 were used instead of words to indicate pain levels. Divide a straight line into 10 segments and describe pain on a scale of 0 to 10). The incidence of postoperative nausea and vomiting within 3 days after surgery was recorded.Adverse events were recorded every day until postoperative day 3, including hypotension, hypertension, bradycardia, tachycardia, hypoxemia, and interventions (adjustment or stoup study drug infusion or intravenous administration). Hypoxemia treatment options included oxygen supplement or endotracheal intubation. Systolic blood pressure less than 90 mmHg or 25% below baseline was considered hypotension, while that more than 160 mmHg or 25% high baseline was considered hypertension. A heart rate less than 50 bpm was recorded as bradycardia, while that greater than 100 bpm was recorded as tachycardia. Oxygen saturation less than 90% was considered hypoxemia.The occurrence of non-delirium postoperative complications as well as the 30-day all-cause mortality were recorded by follow-up.