Ethics approval and consent to participate
This study received approval by the Medical Ethics Committee of the Affiliated Hospital of North Sichuan Medical College (2022ER403-1) on 04/10/2022, with registration on ClinicalTrials. gov and the Chinese Clinical Trial Registry (ChiCTR2200065279) on 01/11/2022. Written informed consent was obtained from every patient by the investigators, and this work was conducted in accordance with the Declaration of Helsinki.