1. Introduction
liver cyst, Hepatic carcinoma, ischemia, hepatic ischemia reperfusion, injury of the liver, postoperative adverse reactions
LIVER CYST, INFLAMMATORY RESPONSES, HEPATIC CARCINOMA, ISCHEMIA, LIVER ABSCESS, MALIGNANT TUMORS, PERIOPERATIVE COMPLICATION, OXIDATIVE STRESS, DISEASES
Hepatic carcinoma is one of the most common malignant tumors worldwide. Clinically, partial hepatectomy is still the most effective surgical treatment for hepatic carcinoma, liver abscess, liver cyst, or other diseases [Recently, various studies focus on the protective effects of ischemic preconditioning on organs. The concept of direct ischemic preconditioning (DIPC) was first proposed by Murry et al. in 1986; it was confirmed to inhibit the secretion of inflammatory factors and reactive oxygen species (ROS) through stimulating the release of adenosine, nitric oxide, or other substances directly, which could strengthen the capacity in withstanding injury [This study focused on comparing the protective efficiency of DIPC and RIPC on ischemia reperfusion injury of the liver in patients undergoing partial hepatectomy. We evaluated the changes of intraoperative hemodynamics, liver function, liver reserve capacity, oxidative stress, and inflammatory responses 24 hours after surgery and postoperative adverse reactions. These results may help to explore new strategies in alleviating hepatic ischemia reperfusion injury with fewer perioperative complications.