Introduction
hepatitis B infection, cirrhosis, Cirrhosis, HBV infection
CIRRHOSIS, INFECTION, HEPATITIS B INFECTION, CIRRHOSIS, SUPERINFECTION, DISEASES
The burden of hepatitis B infection is highest in the WHO Western Pacific Region and the WHO African Region, where 116 million and 81 million people, respectively, are chronically infected. Sixty million people are infected in the WHO Eastern Mediterranean Region, 18 million in the WHO South-East Asia Region, 14 million in the WHO European Region and 5 million in the WHO Region of the America [Superinfection of HDV in individuals with HBV infection leads to progressive diseases and cirrhosis in approximately 80% of cases. Cirrhosis develops at a younger age than in patients with chronic HBV infection only [The course of HBV infection and progression of chronic HDV infection may depend on host and viral factors [