Limitations
infarct
INFARCT
This was a single-center study, and the sample size was not large enough. Perhaps the results of expanding the trial will be more applicable to our clinical practice. In addition, it is unfortunate that plasma ANP and CNP levels were not measured in this study due to due to their rapid clearance in circulation. Imaging indicators such as cerebral blood perfusion, brain tissue metabolism, and changes in infarct volume were not used as efficacy evaluation indicators. Plasma BNP, Corin, and NEP levels were tested less frequently, only before and 5 days after administration.