Explanation for the choice of comparators {6b}
fractures
STERILE
A matched placebo of normal saline will be used as the comparator group. Saline provides an inert sterile solution that visually matches the study solution that contains the dose of gentamicin, allowing for the masking of the study intervention from the care providers at the time of administration. All other standard of care measures in the treatment of open tibial fractures will be offered to all participants.