Discussion
NSCLC, squamous cell carcinoma [, adenocarcinoma
SQUAMOUS CELL CARCINOMA, PATHOLOGY, ADENOCARCINOMA, NSCLC
In our study, it was found that dissecting the surgical specimen before formaldehyde exposure provided more accurate staging since the dissected number of N1 lymph nodes and multiple N1 positivity was higher in the surgical group than in the pathology group. Lymph node involvement is one of the most critical factors determining the prognosis of NSCLC. NSCLC cases with mediastinal lymph node involvement have a poor prognosis. Therefore, intraoperative mediastinal lymph node sampling/dissection is important for staging and deciding the course of the treatment. The T factor was revised in the last TNM stage, since one of the reasons for the differences in survival was the size of the mass. While it is planned to provide more accurate predictions with the changes in the T factor in the 8th staging, the debates on the detection of N1 lymph node involvement and prognosis continue. Variable results in patient survival suggest that different prognostic factors exist; studying these variables is imperative to provide the ideal treatment modality to the patient for better prognosis.Maeshima et al. emphasized that multiple N1 positivity was a poor prognostic factor [In a series of 1742 patients with NSCLC, hilar lymph nodes were divided into three groups according to N1 lymph node involvement: single hilar, single interlobar and multiple N1 positive. These groups were compared among themselves as well as with patients with single N2. It was observed that patients with multiple N1 and patients with single N2 had similar survival rates [It is generally pointed out that N1 lymph node involvement is more common in patients with adenocarcinoma than in those with squamous cell carcinoma [