Authors’ contributions {31b}
XH is the Chief Investigator; she conceived the study, led the proposal and protocol development and wrote the first draft of the protocol. XH, KSS, EL, FN, OL, PL and KB contributed to the study design, development of the proposal and securing trial funding. PL is responsible for the statistical analysis, and FN is responsible for the health economic analysis. All the authors have read and approved the final manuscript.