Randomization and treatment
Patients were randomized to one of two treatment groups, namely once daily ASAQ and twice daily AL. Randomization was stratified according to patient age using separate computer-generated randomization lists. Three age strata were used: 6–59 months, 5–9 years, and 10–14 years. The treatment information was placed in a sealed envelope. Each study participant was randomly assigned (1:1) to receive either ASAQ or AL.Treatment dosages were determined according to patient body weight [