Discussion
MH, PCOS, HT, atherosclerosis, TG
CVD, ATHEROSCLEROSIS, DISORDERS, ENDOTHELIAL DYSFUNCTION
Our results showed that total scores and RP and RE scores in the SF-36 scale after treatment in the two groups were significantly higher than before treatment, whereas PF, MH, and HT scores were significantly lower than those before treatment, after adjusting clomiphene and reproductive outcome. In the ChiQOL scale, the significant increase in total scores and emotion domain scores was observed in the two groups compared with pre-treatment. These findings indicated that acupuncture could improve the emotion domain of PCOS patients, and the same effects were found in sham acupuncture. The SF-36 questionnaire-a is a concise health survey that comprehensively summarizes the survival quality of respondents; it contains 36 items divided into nine areas of HRQoL. Our study revealed that acupuncture significantly improved the scores of RP and RE in SF-36 of patients with PCOS, which were decreased after acupuncture treatment in previous research (The level of serum Hcy was significantly decreased after treatment in both groups (adjusted Our research found that acupuncture can regulate emotion and improve abnormal lipid metabolism and ion disorders, and these may have a certain relationship. Poor mental health was significantly associated with elevated levels of TG and LDL-C. A recent cross-sectional study demonstrated that female participants who experienced high stress showed higher levels of LDL-C compared with the low-stress participants, suggesting that higher levels of blood lipids and lipoprotein α were related with psychological stress and emotional disorders (We found that the changes of emotion and lipid provided molecular biological evidence for the scientific connotation of the theory of liver governing emotion in TCM. A previous study also found that acupuncture could effectively modify hepatic lipid metabolism by increasing the sensitivity to leptin. This is consistent with the theory of liver master sentiment in TCM (Additionally, we found that the levels of serum Cl, serum Ca, and serum K have been both significantly increased in the acupuncture group after an intervention of 4 months compared with pre-treatment (adjusted In our study, a decrease in Hcy levels after acupuncture intervention was of novel interest. Studies have illustrated that elevated concentration of Hcy can affect blood vessels, which may have contributed to the deterioration of atherosclerosis and endothelial dysfunction by damaging the blood vessel, thus increasing the risk of CVD (