Clinical and demographic data
migraine
MIGRAINE, MIGRAINE WITH AURA
Twenty-three participants with episodic migraine (22/23 females, 95.7%) of whom 14 had migraine with aura (14/23, 60.9%), and 27 HC (21/27 females, 77.8%) enrolled in the study. During the experimental period, there was no dropout. Their average age was 38 ± 13 years and 33 ± 11 years, respectively (p = 0.107). Eleven migraineurs received active tDCS (11/23, 47.8%). The average age of participants in the active tDCS and the sham tDCS group was 41 ± 15 years and 34 ± 10 years, respectively (p = 0.288). During the baseline period, the number of migraine days did not differ statistically significantly (p = 0.134) in these groups (5 ± 3 days and 6 ± 3 days, respectively). See Table Baseline data of the included sample; all patients diagnosed with migraine with aura also had attacks without aura.The number of days passed since the last attack was 7 ± 7 days in the active tDCS group and 4 ± 5 days in the sham group (p = 0.475) at the baseline visit. The number of days to the next attack was 11 ± 15 days in the active tDCS group and 4 ± 4 days in the sham group (p = 0.246, 1 missing).F1 took place, on average, 49 ± 7 and 50 ± 9 days after the baseline examination in the active tDCS group and the sham group, respectively (p = 0.695). In the 28-days preceding F1, participants in the active group had 4 ± 3 migraine days and participants in the sham group had 6 ± 2 migraine days (p = 0.169). The number of days passed since the last attack at F1 was 5 ± 6 days in the active tDCS group and 2 ± 2 days in the sham group (p = 0.866; 1 missing). The number of days to the next attack was 10 ± 25 days in the active tDCS group and 6 ± 5 days in the sham group (p = 0.227, 1 missing).F2 took place 210 ± 64 days and 226 ± 73 days after the active and sham group baseline examination, respectively (p = 0.347). In the 28 days preceding their examination, participants had 5 ± 4 and 7 ± 3 migraine days, respectively (p = 0.180). The number of days passed since the last attack at F2 was 14 ± 12 days in the active tDCS group and 6 ± 7 days in the sham group (p = 0.077); the number of days to the next attack was not recorded.