Competing interests
Drs. Inturrisi and Manfredi are inventors on patents related to esmethadone. Drs. Traversa and O’Gorman are employees of Relmada Therapeutics. Drs. Manfredi, Pappagallo, Inturrisi, Folli, and Kosten have received compensation from Relmada Therapeutics as consultants. Drs. Shram, Henningfield, Apseloff, Gorodetzky, De Martin, Vocci, Sapienza, Huston, Buchhalter, Ashworth, Lanier, Mattarei, and Guidetti are employed or have received compensation from companies or institutions that received funding from Relmada Therapeutics.