Criteria for discontinuing or modifying allocated interventions {11b}
cirrhosis
CIRRHOSIS, COMPLICATIONS
There are two contexts in which a patient may modify the allocated intervention. These are named in the context of the trial switchers.T-to-C-switcher: patients, randomized in the TIPS group (T), but who are not in the constitution for this procedure or develop contraindications for TIPS procedure between randomization and day of planned TIPS placement (max 72 h), respectively and drop into standard of care treatment (Control, C).C-to-T-switcher: patients, who are initially assigned to standard of care (C) but develop complications of cirrhosis in which TIPS placement is indicated during follow-up and hence drop in TIPS treatment (T).