Injection protocol
The dilution of botulinum toxin was performed by an experienced technician. Injections were performed in an upright position by an experienced surgeon. This was considered safe because for the dilution with normal saline, we followed the exact instructions of the manufacturers (available in product packages), and for the dilution with lidocaine, previous numerous studies on lidocaine in combination with different materials or alone have found it safeInjection sites: 1. Edge of the corrugator muscle; 2. The distance between the previous 2 points on the nose; 3. About 1 cm above the supraorbital notch; 4. About 1 cm above point #3 on each side, two new points were selected on the frontal muscle with equal distances; 5. About 1 cm above points #4 and between these points, three new points with equal distances were selected on the frontal muscle; 6. The tail of the eyebrow; 7. The edge of the temporal line; 8. Around the eye at the location of the orbicularis oculi muscle on the lateral rim of the eye, two points were selected.