Results
gastrointestinal, hepatobiliary-pancreatic), arthritis
MAY, ARTHRITIS
141 patients that had undergone abdominal major surgeries from November 2020 to May 2022 (e.g., gastrointestinal, hepatobiliary-pancreatic) were included in the trial. Among them, 69 were randomized to the rEEG-guided group and 72 to the routine care group, respectively. Taking into account the 5 patients within the rEEG-guided group and 4 within the routine care group, a technical failure of EEG monitoring prevented the clinicians from analyzing the EEG results. Missing data was distributed almost evenly between the two groups, the final 125 patients were included in the outcome analysis, 61 in the rEEG-guided anesthesia management group and 64 in the conventional anesthesia management group (Fig. 
Flow diagram of included patients
Patient characteristics in each groupRheumatoid arthritis or connectivetissue diseaseValues are presented as number (%) or median (1Q, 3Q). ASA: American Society of Anesthesiologists classification; ICU: intensive care unit