5. Conclusions
DENTAL CARIES
In conclusion, the present study is the first to demonstrate the effect of probiotics on the composition of the supragingival microbiota during short-term sugar stress in healthy individuals. Specifically, the intake of probiotics stabilized bacterial diversity, induced partial resistance against fluctuations, and augmented the resilience of the supragingival microbiota. Future studies with larger sample sizes are needed to elucidate the clinical and immunological impact of sugar stress, while long-term studies are needed to reveal the potential clinical impact of these probiotics in the context of dental caries.