Statistical Analysis
SECONDARY
The sample size calculation was based on an effect size of 0.55 on the ARAT score obtained from a meta-analysis.We followed the prespecified statistical analysis plan, which is available in the We performed similar analyses for the effect of treatment on the secondary outcomes at all visits except for the mRS and length of stay. The mRS was analyzed using a cumulative link mixed model of the total mRS scores due to the ordinal nature of the data. The effect of treatment on the length of stay and the dose of upper limb therapy and self-practice that patients received were analyzed with independent samples Statistical analysis was performed with R 4.1 and SPSS 26.0 (IBM, Chicago, IL). All hypotheses were tested a 2-sided alpha of 0.05.