Discussion
TTP reduction, TTP
SECONDARY, TTP, EARLY PREGNANCY
To the best of our knowledge, this is the first randomized controlled study investigating a shorter endometrial exposure to oestrogens (only 7 days) before starting P4 supplementation in a FET with HRT. In fact, the current results show similar clinical pregnancy rates between 7 versus 14 days of oestrogens priming in a FET HRT, opening the floor for future larger scale RCTs with the aim to confirm these exploratory results.The wider implications of such a study are the TTP reduction which could reduce the costs but also increased patient comfort and acceptance when choosing FET over fresh ET [The results of the present study are in line with a retrospective cohort study that was published in 2022, [The basis of our hypothesis to shorten the TTP was inspired by Navot et alThe duration of oestrogen administration before frozen embryo transfer did not impact implantation nor clinical pregnancy and early pregnancy loss or live birth rate from a statistical point of view, as shown by Sekhon et alOur primary and secondary outcomes were similar to the results of the FET-HRT population in most studies comparing eFET with fresh ET [