Conclusions
infectious complications, postbiopsy, infections, prostate, postbiopsy infection, postbiopsy infections
INFECTIONS, PROSTATE, PROSTATE
Our study supports the use of culture-based prophylaxis to reduce infectious complications after transrectal PB. Despite adequate prophylaxis, postbiopsy infections can still occur. Therefore, culture-based prophylaxis must be weighed against other strategies that could reduce postbiopsy infections.
Our study supports using culture-based prophylaxis to reduce infectious complications after transrectal prostate biopsy, especially with regard to the early, more severe infections. Despite adequate prophylaxis, patients can still develop postbiopsy infection; therefore, other strategies need to be explored as well.Prostate biopsy (PB) is commonly performed using a transrectal ultrasound-guided approach. Unfortunately, transrectal PB may cause infections from introduction of enteric bacteria, particularly Enterobacterales such as Traditionally, fluoroquinolones (FQs) are used as prophylaxis because of their coverage against common causative bacteria of postbiopsy infections and favorable prostatic penetration [A plausible strategy to overcome the problem of postbiopsy infections related to FQ-resistant Enterobacterales is rectal culture–based antibiotic prophylaxis [Previous studies reported conflicting results regarding the impact of rectal culture–based prophylaxis on postbiopsy infection rates [