Outcomes
SARS-CoV-2 infection
SARS-COV-2 INFECTION
We did a post-hoc analysis of durability of antibody responses comparing AZD1222 recipients with and without SARS-CoV-2 infection before receipt of the first dose. Another post-hoc study objective was evaluation of ADCC through to day 180 in a convenience subset of 30 samples, which screened positive for anti-S IgG and for which sufficient residual sample was available. Because of the highly intensive nature of the ADCC assay, testing was limited to targeting D614G and delta on the basis of previous observation that Fc effector function is conserved across variants.