Metabolomic signatures vary based on clinical outcome measure
DISEASE
Clinical outcome measures used in the MGTX study assess a patient’s status from their own perspective (MG-ADL) an examiner’s assessment of muscle strength at a given time (QMG), and a snapshot of a physician’s global impression of the patient (MMS). Several studies have demonstrated that these measures correlate only in a moderate fashion indicating that they are assessing varying and non-overlapping aspects of the disease [