Outcomes
myocardial infarction, patent mesenteric ischemia, RIFLE, hypotension, renal damage, hypokalemia, VFDs
HYPERNATREMIA, EVENT, MYOCARDIAL INFARCTION, EVENTS
The main outcome was vital status at Day 60 (alive vs deceased). Secondary outcomes included mechanical ventilator-free days (MVFDs) and vasopressor-free days (VFDs), defined as the cumulative number of days alive with no mechanical ventilation (or no prescription of vasopressor, respectively) between Day0 and Day28; renal replacement therapy-free days (RRTFDs), defined as the cumulative number of days alive with no renal replacement therapy between Day0 and Day60; occurrence of at least one unexpected harmful event (arterial hypotension, i.e. arterial systolic pressure < 90 mmHg, between Day2 and Day14; hypernatremia, i.e. serum sodium level > 155 mmol/L, between Day2 and Day14; hypokalemia, i.e. serum potassium level < 2.8 mmol/L, between Day2 and Day14; or acute ischemic events, i.e. myocardial infarction and/or patent mesenteric ischemia, between Day3 and discharge); and renal damage, defined by a worsening in the RIFLE criteria between Day3 and Day14, as compared to the higher RIFLE criteria during the first two days of hospitalization [