Introduction
LGRs, attachment loss
Gingival recession (GR) is a clinical condition defined by the apical shift of the gingival margin below the cemento-enamel junction (CEJ). It is associated with attachment loss and with exposure of the root surface. When the loss of attachment and marginal tissue recession are predominantly found at buccal surfaces, these lesions are usually present in populations with high standards of oral hygiene [The treatment of LGR aims to reconstruct the lost soft tissues and to fully cover the exposed roots. With this purpose, several surgical techniques have been proposed combining different surgical designs (flaps and tunneling approaches) and grafting materials (autologous, allogenic, or xenogeneic) [Tunneling techniques (TUN), always in combination with a CTG, have also demonstrated high clinical efficacy in the treatment of multiple adjacent LGRs [The existing randomized clinical trials (RCTs) comparing CAF with TUN for the treatment of multiple adjacent LGRs have reported conflicting results, probably due to patient and site selection (combination of single and multiple LGRs) [