References
liver or kidney diseaseConditions, allergy
ADVERSE EVENTS, OXIDATIVE STRESS, ALLERGY
Flowchart of the study.PROMIS Global Health-10 scores at baseline and at the end of the study, separated by (Changes in biomarkers of oxidative stress during the 4-week detoxification study. (Changes in redox homeostasis during the 4-week detoxification study. (Changes in the activity of the phase II antioxidant enzymes during the 4-week detoxification study. (Inclusion and exclusion criteria of the study.Healthy adults in college settings aged 18–65Willingness to comply with study protocol for 30 daysNo allergy to the ingredients in the study productSubject is a male or a nonpregnant, nonlactating female, at least 6 weeks postpartum prior to screening visit, and is not actively planning a pregnancyIf on a chronic medication (that does not result in exclusion), subject has been on stable dose for at least two months prior to screening visitSubject has at least two-week wash-out period between completion of a previous research study that required ingestion of any study food or drug and their start in the current studySubjects who are experiencing any adverse events due to any nutraceutical, OTC, pharmaceutical, or investigational productsCeliac and other gastrointestinal health concernsLipid lowering drugs or the use of anticoagulant medications in the preceding 4 weeksPregnant and/or nursingTotal cholesterol levels < 220Subjects with untreated endocrine, neurological, skin or infectious diseasesSignificant liver or kidney diseaseConditions affecting joint healthSerious medical illness, including cancerUse of ethanol within 24 h of the evaluation visits (baseline, 4 weeks)Demographic and anthropometric data of the study participants (±SEM).Results are expressed as means ± SEM (** Hepatic detoxification markers in urine (±SEM).