2.1.5. GO enrichment analysis and KEGG pathway enrichment analysis.
RA
The drug-disease intersection targets were imported into the Database for Annotation, Visualization and Integrated Discovery (DAVID), and the species was set as human species. The kyoto encyclopedia of genes and genomes (KEGG) pathway and Gene Ontology (GO) enrichment analyses were submitted to establish a “core target-biological pathway” network to screen out the major pathways. The KEGG enrichment bubble chart and GO term enrichment were created online using the results of bioinformatics analysis to reflect the interactions between drug targets and RA target-related pathways.