Funding
 The ADAMPA study was funded by the Instituto de Salud Carlos III from the Spanish Ministry of Research, Innovation and Universities (Grant Pl16/02130 and RD16/0001/0011, cofinanced by the European Regional Development Fund) and had the collaboration of the SCReN Platform (Spanish Clinical Research Network from the Instituto de Salud Carlos III; Grants PT13/0002/0031 and PT17/0017/0003).