Visual analysis
primary lung tumor
DISEASE, RECURRENCE, TUMOR RECURRENCE, SENSITIVITY
We report interobserver agreement (IOA) between 4 observers on 114 examinations. Overall IOA for the examination based evaluation of disease relapse was moderate (ĸ = 0.57) with substantial agreement between the observers for the assessment of tumor recurrence in the primary lung tumor (ĸ = 0.61) and distant recurrence (ĸ = 0.69). The evaluation of lymph node recurrence in the mediastinum showed moderate interobserver agreement (ĸ = 0.58). Comparing the evaluation without and with additional knowledge about the initial staging PET and the dedicated radiotherapy delineation volumes, there was no statistically significant difference in kappa values of IOA. Additionally, we classified examinations as unequivocal if all 4 observers reported to be sure in their judgement about the examined entity, and equivocal otherwise. In secure cases where all observers felt certain in their assessment, IOA showed substantial agreement for the assessment of the primary lung tumor (ĸ = 0.74, Interobserver agreement of the visual assessment* (-) additional information about the initial staging PET and the dedicated radiotherapy delineation volumes was not provided, ( +) additional information about the initial staging PET and the dedicated radiotherapy delineation volumes was providedPooled sensitivity and specificity of the visual evaluation by the four observers are displayed in Table Sensitivity and Specificity of the visual and the threshold-based assessment