2.1. Study Design and Patients
diabetes mellitus, bone disorders
SYSTEMIC DISEASE, HEMORRHAGIC DISORDERS, DIABETES MELLITUS, OSTEOPOROSIS, BONE DISORDERS
This study was a prospective, randomized, and controlled clinical trial. Patients were recruited from the outpatient department of the Department of Periodontology, Krishnadevaraya College of Dental Sciences, Bengaluru.Patients over the age of 18 exhibiting a keratinized tissue width greater than 1.5 mm, Siebert’s class I and II defects corresponding to Cologne’s classification h1e and h2e defects, and with a span of not more than 25 mm, were included in the study. Patients with poor oral hygiene, thin biotypes (<0.8 mm), systemic diseases such as uncontrolled diabetes mellitus or hemorrhagic disorders, bone disorders such as osteoporosis, and who are taking immunosuppressive drugs were excluded from the study.A total of 20 healthy adults aged between 21 and 60 years and exhibiting inadequate alveolar ridge dimensions in the maxillary and mandibular regions were randomized into test (The study was performed in compliance with the ethical guidelines outlined in the World Medical Association Declaration of Helsinki (version VI, 2002). Ethical approval was obtained from the Ethical Committee of Krishnadevaraya College of Dental Sciences (affiliated with Rajiv Gandhi University of Health Sciences). Furthermore, all participants were apprised of the nature of the study, as well as the potential benefits and risks of their participation. All participants provided informed written consent.