Acknowledgements
We would like to thank all patients, their families, and the investigators who participated in this trial. We would like to thank the following colleagues at F. Hoffmann-La Roche Ltd for their contributions and support to the study: Jan Beckmann, Sandro Fritz, Nicholas Pierce Heinemeier, Timothy Kilchenmann, Lito Kriara, Grégoire Pointeau, Cedric Simillion, Jens Schjodt-Eriksen, Jörg Sprengel, and Mattia Zanon. Writing and editorial assistance for this manuscript was provided by Terri Desmonds, PhD, from Articulate Science, United Kingdom, and funded by F. Hoffmann-La Roche Ltd.