Luvadaxistat did not affect EBC
The primary endpoint for this study was the average percentage of conditioned responses during the EBC test at day 8 as analyzed by ANOVA. The least-squares (LS) mean change from baseline in percentage conditioned response at day 8 was 0.597 ± 0.459 (estimate ± standard error of the mean [SEM]) for subjects treated with luvadaxistat 50 mg compared with 0.319 ± 0.432 for those treated with placebo and was 0.578 ± 0.444 for subjects treated with luvadaxistat 500 mg compared with 1.344 ± 0.428 for those treated with placebo (Fig. 