Data source and study design
Rheumatoid Arthritis
RHEUMATOID ARTHRITIS
The ABC trial was a 12-month prospective, multicenter, post-marketing, cluster (at the physician level) randomized study, with the option to participate in a 12-month extension phase for patients who completed the initial 12-month study. Physicians were randomized in a 1:1 ratio to either receive formal education on the T2T approach (T2T group) prior to the study or not receive training and instead continue managing through their judgment and RC (RC group). Physicians in the T2T group were provided with a thorough review of the T2T approach by T2T experts, and were encouraged to follow suggested treatment optimization options, as well as the Canadian Rheumatology Association Recommendations for Pharmacological Management of Rheumatoid Arthritis with Traditional and Biologic DMARDs [