The median fold change in CA US HIV-1 RNA per time point and per treatment arm compared to the control arm.
*Mann-Whitney †Wilcoxon signed-rank sum test.As a consequence of the treatment adjustments, the 6-hour time point after the first dosing is the only sampling time point where all participants were similarly exposed to their allocated therapies and at the same doses. We therefore focused on the effects observed here as the most unbiased measurement time point consequent to drug treatment. From baseline to 6 hours, CA US HIV-1 RNA increased median 2.1-fold (IQR, 1.5 to 2.7; 