Outcomes
death, SD
DISEASE PROGRESSION, DISEASE, SECONDARY
The primary endpoint was clinical benefit rate (CBR) according to the RECIST v1.1, which is defined as the proportion of patients who achieved confirmed complete response (CR), partial response (PR), or stable disease (SD) lasting for 24 weeks. The secondary endpoints included objective response rate (ORR, defined as the patients with confirmed PR or CR), PFS (defined as the time from enrollment to first documented disease progression or death from any cause), and AEs.