Authors’ contributions {31b}
RA
CR is the Principal Coordinating Investigator, she conceived the study, and led the proposal and protocol development. She wrote the manuscript. SP is the Project Manager in the ZKS. She has driven the protocol development. She wrote the manuscript. PF is the biometrician. He has performed the statistical analysis plan. RA is the radiologist. He has contributed to the technical data for the protocol and the radiation regulatory authorities. US is a biometrician. She has supervised the statistical analysis plan. AW is a biometrician. He had performed the sample size calculation (Halle). Once the PI changed centers (from Halle to Jena), AW was no longer part of the team. He is actually on the DSMB. AS is the director of the Clinic for Internal Medicine IV in the Jena University Hospital. He has facilitated protocol development. JS is the director of the KKS in Halle. He had an important role in proposal development and achieving funding. AZ is the co-Chief Investigator. He has contributed to the proposal and protocol development. All authors read and approved the final manuscript.