Authors’ contributions
MH, RP, HC
DC is the chief investigator. DC, NS, IC, GA, SS, MH, TR, DL, MA and CP reviewed and contributed to the protocol design, with RB and IR contributing heavily to the biological specimen collection plan. MA is the senior statistician who is supported by CP, the lead statistician for the department. SS, RL and VB will recruit and follow up patients. AB, HC and RP are managing and coordinating the study. OZ is involved in managing the database and reviewing data for completeness and integrity. All authors reviewed and approved the manuscript, in accordance with the ICMJE guidelines for authorship (substantial contributions to the conception or design, or acquisition, analysis or interpretation of data, and drafting/revising it critically) and agree to be accountable for all aspects of the work.