Considerations for the forthcoming intervention study
toxicity, Chagas disease, leishmaniasis
SECONDARY, CHAGAS DISEASE, LEISHMANIASIS
This study provides cluster specific information on socio-economic indicators and cluster size, on the estimated mosquito abundance, the main breeding places and their pupal productivity, the type and size of water containers, water use for drinking and cleaning which should be considered for the planning of the intervention (covering the productive water containers with a protective and transparent coating) and implementation of the CRT in randomly assigned clusters (using incidence rates and entomological indicators) into intervention and control clusters. The intervention in these ground tanks should be safe for human consumption as a small proportion of households (2.2%) uses the water is also for cooking and drinking. Moreover, people’s willingness to accept the insecticidal coating in their laundry tanks was high in all clusters (88.3%) based on the information, that a sub-study with water samples (to be presented in a different paper) showed no toxicity of the paint and will be delivered for free. Previous studies in Nepal and Bangladesh found that the application of insecticidal coating on house walls was safe and well accepted by communities and health workers. High acceptance (94%) of the households’ participants was reported in the control of leishmaniasis and Chagas disease [A specific challenge for assessing the effectiveness of vector control interventions is people’s mobility during the day as 40.3% of the people in our sample used to leave the cluster area during the day at least for some hours so that they can get infected in other places and bring the viruses home. Male, adult people (20 years and older) and people in secondary education had higher proportion of time spent outside their clusters. This finding is similar to a study in Mexico which found differences in human mobility according to gender and age [The novel insecticidal coating contains two active ingredients pyriproxyfen and alphacypermethrin which have both been widely evaluated for vector control. The concept of coating of surfaces with micro-encapsulated insecticidal/larvicidal products for vector control has gained special attention in comparison with other vector control methods such as insecticide-impregnated bednets, and indoor residual spraying [