Results
At baseline, household characteristics, LLIN coverage, and entomological and epidemiological indicators were similar in the four study groups.A total of 146 936 mosquitoes were collected over the 3 successive years, of which 34 605 (23·6%) were female anophelines, principally We observed differential effects of the dual active-ingredient LLINs on separate vector species, with the greatest effect on Differential effects of the dual LLINs compared with standard pyrethroid LLIN on The intervention group was compared to the standard pyrethroid LLIN group at each timepoint. Density ratios were adjusted for baseline cluster-level variables used in restricted randomisation. We applied a Bonferroni correction for multiplicity given the multiple comparison groups. p<0·017 was considered statistically significant. LLIN=long-lasting insecticidal net. aDR=adjusted density ratio.There was weak evidence of a difference in There was no strong evidence in any of the interventions groups of reduced overall sporozoite rate, compared with the standard pyrethroid LLIN group, over the 3 years of the trial (Effect of dual LLINs compared with standard pyrethroid LLIN on sporozoite rate and EIRThe intervention group was compared with the standard pyrethroid LLIN group at each timepoint. Odds ratios for sporozoite rates and density ratios for EIR were adjusted for baseline cluster-level variables used in restricted randomisation. EIR aDRs were weighted to account for the proportion of mosquitoes sampled to be tested for sporozoites. We applied a Bonferroni correction for multiplicity given the multiple comparison group. p<0·017 was considered statistically significant. LLIN=long-lasting insecticidal net. EIR=entomological inoculation rate. aDR=adjusted density ratio.Chlorfenapyr pyrethroid LLINs were also effective in reducing In the study area, the relative vector-species abundance and distributions varied between southern and northern clusters (Most Proportion of Comparisons were done between each of the interventions groups versus the reference group (pyrethroid only) for each year separately, and then combined. The proportion of When tested with independent postintervention data, MaxEnt pilot ecological niche models for Species distributionPredicted species distribution maps based on ecological models for (A) 