Long-term effectiveness outcomes
muscle mass, renal disease, multimorbidity, diabetes
CVD, RENAL DISEASE, SECONDARY, BLOOD, DIABETES
The key study outcomes are the incidence of diabetes and CVD risk at nine years after the intervention. Other primary outcomes include Blood pressure, weight, HbA1c, triglycerides, SF-36, and tobacco. Additionally, body mass index, fat percent, muscle mass, waist circumference, diastolic blood pressure, Fasting Plasma Glucose, lipid profile (total cholesterol, LDL cholesterol, and HDL cholesterol), current alcohol use, diet, and physical activity will be assessed. New measures of pre-clinical retinal microvasculature, heart function and renal disease are also being assessed. We are also considering multimorbidity as a secondary outcome in this follow-up study.