Ethics approval and consent to participate
We've been waived the need for informed consent by Ethics Committee of Zhongshan Hospital, Fudan University. Because the subject cannot be found in the research using human body materials or data with identifiable information, and the research project does not involve personal privacy or commercial interests. The study was retrospectively registered (No. CJ0647) and approved by Human Genetic Resources in China in April 2022. Ethical approval was received from the Medical Ethics Committee of Zhongshan Hospital (NO.B2021-839R). All methods were performed in accordance with the relevant guidelines and regulations.