Explanation for the choice of comparators {6b}
silicone tCDC
Previous studies that used stiffer polyurethane tCDCs and had different methodological issues have demonstrated higher incidence of CVS after subclavian catheterisation as compared to internal jugular catheterisation. As the subclavian route offers several advantages, the current study will investigate if the incidence of CVS after insertion of a soft silicone tCDC in the right-sided subclavian vein is non-inferior compared to the right internal jugular vein which, in clinical practice, is the vein most commonly used.