Ethics approval and consent to participate
Ethical approval for this clinical study (NO. KY20202065-X-1) was provided by the Medical Ethics Committee of the First Affiliated Hospital of the Fourth Military Medical University on 7 April 2021. All participants or their legal representatives provided written informed consent before enrollment. The trial was registered before patient enrolment at Chinese Clinical Trial Registry with registration number ChiCTR2100046479 (date: 16/05/2021), and adhered to the Consolidated Standards of Reporting Trials guidelines and the Declaration of Helsinki.