Ethics approval and consent to participate
The study is conducted according to the principles of the Declaration of Helsinki (version 64th, October 2013) and in accordance with the Medical Research Involving Human Subjects Act (WMO) and other guidelines, regulations, and acts. The medical ethics Committee on Research involving Human Subjects (CCMO, Arnhem-Nijmegen) approved the study and is registered under 2021–8224.Written informed consent regarding participation and publication from all parents or guardians for participants under 16 years will be obtained during the randomized controlled trial.