Statistical analysis
Statistical analysis of the data was performed, and box plots were created using IBM SPSS statistics software version 24 (IBM, Armonk, New York). Continuous variables are expressed as mean ± SD. Unpaired t-test was used to compare between the 2 groups, while paired t-test was used to detect the difference within the group between the beginning of the study and after 3 months. Categorical variables are expressed as numbers (percentage) and were compared using chi-square (X