2.1. Study Design and Subjects
obesity, Obesity
OBESITY, PEDIATRIC OBESITY, OBESITY, DISEASE
We conducted a cross-sectional comparative study that was a branch of a randomized clinical trial where the main objective was to evaluate several physical activity interventions in pediatric patients with obesity who were included in a multidisciplinary lifestyle change intervention program.Children and adolescents aged 8 to 16 years who had not been previously treated and were sent to the Pediatric Obesity Clinic at the Child Welfare Unit in the General Hospital of Mexico were eligible. Obesity was defined using the Centers for Disease Control and Prevention criteria (body mass index (BMI ≥ 95th percentile according to age and sex)), and only Class 1 obesity participants were included (BMI < 120% over 95th percentile according to age and sex) [The study was approved by the Hospital’s Institutional Research, Ethics, and Biosafety for Human Research Committees (Number DI/17/311/03/028) and registered in ClinicalTrials.gov (NCT03552367). Parents and children provided written informed consent and assent, respectively. This trial was conducted in accordance with the 1975 and 2013 Declarations of Helsinki and adhered to the Good Clinical Practice Guidelines issued by the International Conference of Harmonization. All patient data were protected in compliance with the Health Insurance Portability and Accountability Act (HIPAA).