Statistical analysis
A Kolmogorov–Smirnov test was used to evaluate the normal distribution of the quantitative data. Normally distributed measurements are presented as mean±SD. Measurements with skewed distributions are presented as medians (interquartile range) and all categorical data as percentages. Levene’s test was used to evaluate the homogeneity of data variance. The significance of normally distributed or approximate normally distributed data was evaluated using a Student 