Model structure
dMMR/MSI-H stage, PD, death
DISEASE
To compare the cost-effectiveness of pembrolizumab versus chemotherapy in patients with dMMR/MSI-H stage IV CRC, a PSM was developed to simulate the process of dMMR/MSI-H mCRC depending on the clinical data from KEYNOTE-177. Three distinct health states, PFS, progressive disease (PD) and death (Fig. Structure of the partitioned survival mode