Randomisation
Participants were randomly allocated (1:1) into the control- or SIT LESS group in random block sizes ranging from four to six, using a computerised algorithm (Castor Electronic Data Capture 2021, Ciwit B.V., Amsterdam, The Netherlands). Randomisation was stratified by sex and hospital to ensure balance of the treatment arms. All participants who withdrew within the first two weeks after inclusion were replaced to ensure sufficient power to assess our primary outcome. Due to the nature of the intervention, nurse specialists and patients were not blinded to the treatment allocation.