cancer, tumor, primary tumors, tumors
TUMOR, RECURRENCE, PRIMARY TUMORS, CANCER, PRIMARY TUMOR, TUMORS
To study whether tumor cells with low WRAP53, as a consequence of radioresistance, are enriched in locally recurring cancer after radiotherapy, WRAP53 protein levels were compared between primary tumors and subsequent IBTRs. Using the histoscores (0–12) based on C1‐antibody, 10 tumors (42%) showed reduced protein levels in the recurrence after radiotherapy compared with the primary tumor, seven (29%) did not change and seven (29%) had higher WRAP53 levels in the recurrence after radiotherapy. In the nontreated group, the corresponding numbers were 19 (29%), 25 (38%), and 22 (33%). In the Mann–Whitney 