Missing data
VTE
EVENT
Missing data were managed differently between the two countries. For French re-hospitalization costs related to VTE, one patient out of the six with a VTE event had missing DRG information, so the cost was imputed by the mean re-hospitalization cost of the strategy group. For the Spanish centers, cost data at the index date was not collected for all 36 patients so a multiple imputation was performed by group strategy using a chained model with 25 iterations, regressed on the baseline complete covariates: sociodemographic characteristics (age, sex, body mass index), clinical characteristics, period, and clustering. The imputation model was estimated using predictive mean matching.All analyses were performed with R freeware (version 4.1.2).