Baseline predictors of clinical efficacy
CORTEX
For both stimulation sites, rTMS treatment efficacy was related to baseline connectivity of the stimulation site. For the right stimulation site, antidepressant response was significantly predicted by baseline anti-correlation with bilateral sgACC, anti-correlation with motor cortex, and positive correlation with dorsal ACC (corrected p < 0.05) (Fig. Connectivity profile associated with increased antidepressant efficacy of stimulation sites. White regions depict the a priori subgenual ROI. Clusters detected with threshold of r > 0.8 (uncorrected p < 0.001), minimum extent of 729 mmAntidepressant response was inversely correlated with the right-sided stimulation site’s FC with the a priori subgenual ROI (Fig. The voxel-wise maps of connections that predicted antidepressant response (Fig. 