Intervention
thirty-four
The assigned thirty-four patients were randomly allocated to the following groups:The control group (n = 17) received conventional preventive treatment that was started one day before radiotherapy and applied twice daily for six weeks [The test group (n = 17) were given topical Omega-3 nanoemulgel formulated and characterized with the aid of the Pharmaceutics Department, Faculty of Pharmacy, Alexandria University, as previously mentioned, where 1 g (containing 350 mg of fish oil) was self-applied by patients twice daily, every 12 h, starting one day before radiotherapy and ongoing for six weeks, to ensure a daily dose of (700 mg of fish oil/day) [