Study design
CKD
The present study was a multi-centered, randomized, parallel double-blind, placebo-controlled, phase ΙΙI clinical trial to evaluate the effect of propolis on patients with CKD. This trial was conducted according to the latest version of the declaration of Helsinki and was approved by the Medical Ethics Committee of Tabriz University of Medical Sciences (approval number: IR.TBZMED.REC.1399.177). Furthermore, it was prospectively registered at the Iranian Registry of Clinical trial (registration number: IRCT20191218045798N1) on 07/06/2020 and is available at 