Introduction
migraine, headache
MIGRAINE, HEART, ADVERSE EVENTS, PRIMARY IMMUNODEFICIENCY
Edited by: Francisco Javier Espinosa-Rosales, Fundación Mexicana para Niñas y Niños con Inmunodeficiencias (FUMENI), MexicoReviewed by: Marco Antonio Yamazaki-Nakashimada, National Institute of Pediatrics, Mexico; Soo Jin Cho, Hallym University Dongtan Sacred Heart Hospital, Republic of KoreaThis article was submitted to Primary Immunodeficiencies, a section of the journal Frontiers in ImmunologyHeadache and migraine adverse events are common concerns in the administration of intravenous immune globulins (IVIG). Trials of IVIG for primary immunodeficiency (PI) are typically small and have reported headache and migraine data inconsistently.