Results
DIABETES MELLITUS, INTRAOCULAR PRESSURE
Fifty-two eyes (52 patients) were included, of which 26 eyes were randomly assigned to the 27G group and the others were assigned to the 25G group. Five patients (one in the 27G group and four in the 25G group) were lost to follow-up. The flow diagram is shown in Fig. 
Flow diagram showing the randomization, follow-up and analysis of the intention-to-treat population
Baseline Demographics and Clinical Data of the Two GroupsIIIIIIIVMacula involved2 (8.0%)10 (40.0%)11 (44.0%)2 (8.0%)12 (54.5%)4 (18.2%)9 (40.9%)6 (27.3%)3 (13.6%)10 (45.5%)PhakicPseudophakicAphakic23 (92.0%)2 (8.0%)0 (0%)21 (95.5%)1 (4.5%)0 (0%)*Based on t-test; †based on chi-square test/Fisher’s exact test; ǂbased on Mann–Whitney U test.27G, 27-gauge; 25G, 25-gauge; HbA1c, hemoglobin A1c; preop, preoperative; DM, diabetes mellitus; BCVA, preoperative best-corrected visual acuity; logMAR, logarithm of the minimal angle of resolution; IOP, preoperative intraocular pressure; IVI, intravitreal injection; Anti-VEGF, anti-vascular endothelial growth factor; PRP, panretinal photocoagulation.