Discussion
asthma
ASTHMATIC, ASTHMA
This study is the first to our knowledge to demonstrate an association between eNO in young infants born to mothers with asthma in pregnancy and postnatal air pollution exposure. eNO also showed a significant seasonal variation. Infants born to asthmatic mothers may be more sensitive to the effects of air pollution due to their immature lungs as they are at a higher risk of developing asthma (23) and have lower lung function at 6 weeks of age [The median eNO in this study was similar to the BILD cohort using a coherent methodology [Air pollution has been measured continuously in Newcastle since 1993 [In this study, seasonal variation was observed in both eNO and air pollution concentrations, with mean eNO highest in the warmer months and lowest in the cooler months. The LASSO model identified positive associations for eNO with NHOur study observed a negative association between ambient CO and eNO. Other studies [