Intervention effects
REGRESSION
First, we assessed intervention effects on physical fitness in the sample used in this paper. We executed a multiple regression analysis, with VOWhole brain approaches included average cortical thickness, total grey matter volume, and VBM cluster analyses. Cortical thickness and total grey matter volume were analyzed with multiple regression analyses with cortical thickness or total grey matter volume at follow-up as the dependent variable, and baseline measurement of cortical thickness or total grey matter volume, age, endocrine treatment, and TIV as covariates. For VBM analyses, a basic model for two group longitudinal data was built for the smoothed grey matter segments, where we investigated group-by-time interaction and main effects (CAT12 manual: (As per protocol analyses, all analyses were repeated for patients with a minimal attendance to the exercise intervention of 80 %, which was calculated separately for the supervised exercise program and Nordic/power walking (number of attended sessions / number of offered sessions * 100) and averaged.