Study population
pericoronitis
INFLAMMATION, DISEASE, INFLAMMATORY RESPONSE, PERICORONITIS
The study population was composed of individuals who were indicated for surgical removal of mandibular third molars in symmetrical positions. A signed Informed Consent Form was obtained from each enrolled participant after informing them of the research purposes, risks and benefits.The inclusion criteria were set as: 1) individuals of both genders, 2) aged between 18 and 50 years, 3) classified as ASA I according to the American Society of Anesthesiologists, 4) who have both mandibular third molars in similar positions according to the Pell and Gregory and Winter classifications, 4) absence of pericoronitis or signs of inflammation. The exclusion criteria were: 1) participants who presented a disease or systemic condition that contraindicated the procedure; 2) who were in gestation or lactation period; 3) who used chronic medications or other substances that influence the inflammatory response or bone metabolism; 4) or who refused to participate in the data collection steps were excluded from the study.