Background
caries
HYDROXYAPATITE, CARIES
Edited by: Dominic Augustine, M. S. Ramaiah University of Applied Sciences, IndiaReviewed by: Ralitsa Raycheva, Plovdiv Medical University, Bulgaria; Rodolfo Reda, Sapienza University of Rome, ItalyDental caries is a worldwide challenge for public health. The aim of this 18-month double-blinded, randomized, clinical trial was to compare the caries-preventing effect of a fluoride-free, hydroxyapatite toothpaste (test) and a toothpaste with sodium fluoride (1450 ppm fluoride; positive control) in adults.