Materials and methods
heart disease
HEART, HEART DISEASE
The study is part of a larger study conducted between September 2003 and January 2004 for which joint University of Ibadan/University College Hospital (UI/IRC/02/0041) ethical approval was obtainedClinical information including family history of heart disease was obtained. Physical examination included blood pressure measurement at baseline and at follow up. Twelve lead electrocardiography (ECG) was performed at 0, 6 and 336 hours with a portable ECG machine P80Six, Esaotebiomedica, Italy, to measure the PR and QT interval (QTc). Electrocardiographic parameters were automatically generated by the machine and confirmed by the authors. Heart rate (Hr.) beats/minutes was measured from the R-R interval by dividing the number of large squares (0.20 s) time unit between consecutive R waves into 300 or the small square (0.04 s) time units into 1500Statistical analysis was with SPSS at 5% level of significance.