TMB analysis
TTN, TP53
SOMATIC MUTATION
Using somatic mutation data, the connection between TMB and the risk score was established. According to the waterfall chart, the low-risk group exhibited a higher gene mutation rate compared with the high risk group. Moreover, the PTEN, PIK3CA, ARID1A, TTN, TP53, PIK3R1, KMT2D, CTNNB1, MUC16, and CTCF genes were identified as the top 10 genes with the greatest likelihood of mutation in both high- and low-risk groups. Notably, PTEN, PIK3CA, and ARID1A exhibited the highest mutation probabilities, as shown in F