Introduction
death, smoking behaviors, anxiety
DISORDERS
Tobacco use is the primary cause of preventable death worldwide [A fundamental feature of smoking is the learned associations between smoking behaviors and cigarette-related cues [In the past two decades, memory reconsolidation blockade interventions have shown promise as treatments for stress and anxiety related disorders [Memory updating might also be applied to substance use problems by weakening the ability of drug-associated triggers to elicit substance use [In the present study, we aimed to extend the previous findings and further decrease cigarette smoking using a novel procedure. Given the evidence that stress can potently trigger cigarette cravings [Based on the literature described above, we made two main predictions. First, compared to all other groups, the combined stress and cue procedure would induce greater craving and physiological responses during phase 1 and larger decreases in cue reactivity and cigarette use at two- and six-week follow-up. Second, the stress-based intervention alone would be at least as effective as the cue-based intervention alone.