Technological issues
HYPOGLYCEMIA, HYPERGLYCEMIA
During the study, there were a few technological issues. One participant (during the DH visit) experienced prolonged pressure induced sensor attenuation causing the sensor to register level 2 hypoglycemia, while PG was well within range. This caused wrongful glucagon administration and subsequent hyperglycemia. During two DH study visits, glucagon occluded the pump which required a change of infusion set. During both study arms, the phone lost connection to the sensor. However, all connection issues were automatically reestablished without intervention from the study personnel. These phone-sensor connection issues only triggered an alarm if they lasted more than 15 minutes, thus shorter connection loses may have been present, without the study personnel being aware. Once during a DH study visit, there was a disconnection between the phone and the insulin pumps which was resolved by restarting the entire system.