Introduction
AD and cerebrovascular disease, Cerebrovascular dysfunction, dementia
PATHOGENESIS, ALZHEIMER DISEASE (AD)
Cerebrovascular dysfunction significantly contributes to the pathogenesis of Alzheimer disease (AD). Epidemiological investigations have emphasized the effectiveness of strict control of vascular risk factors as a preventive strategy for dementia, highlighting the strong association between AD and cerebrovascular disease (CVD).Emerging evidence supporting the effectiveness of Aβ immunotherapyIn previous studies by some of us,