2.4. Outcome Measures
dyspepsia, abdominal pain
SECONDARY, SYNDROME
Three primary outcomes were pre-planned: Total GSRS score, GSRS-constipation, and GSRS-diarrhoea scores were compared for change from entry at four weeks. Pre-planned secondary outcomes were indigestion, dyspepsia, and abdominal pain syndrome, which were similarly tested for change from entry at four weeks.The GSRS questionnaire is well documented and has a good reliability, with a Cronbach’s alpha ranging from 0.79 to 0.83 across studies across a number of different languages [