Background
cancer, Inflammation
CANCER, DISEASE, MALIGNANCIES, INFLAMMATION
Edited by: Luisa Giaccone, University of Turin, ItalyReviewed by: Elisabetta Metafuni, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Italy; Sakhila Ghimire, University Medical Center Regensburg, GermanyThis article was submitted to Alloimmunity and Transplantation, a section of the journal Frontiers in ImmunologyIn allogeneic hematopoietic stem cell transplantation (allo-HSCT), prognostic indicators effectively predict survival. The Disease conditions prior to transplantation dramatically affects the outcome of HSCT. Optimization of the pre-transplant risk assessment is critical for enhancing allo-HSCT decision-making. Inflammation and nutritional status play significant roles in cancer genesis and progression. As a combined inflammatory and nutritional status biomarker, the C-reactive protein/albumin ratio (CAR) can accurately forecast the prognosis in various malignancies. This research sought to examine the predictive value of CAR and develop a novel nomogram by combining biomarkers and evaluating their importance following HSCT.