Main
Gliomas, LGGs
GLIOMAS, INFILTRATION, PRIMARY BRAIN TUMORS
Gliomas are a heterogeneous group of primary brain tumors that are associated with diffuse brain infiltration and premature deathMost LGGs in adults harbor mutations in the genes encoding the metabolic enzyme IDH1 or, rarely, IDH2 (refs. Small-molecule inhibitors of mIDH enzymes have emerged as a new strategy for the treatment of m