Statistical analysis
The full analysis set (FAS) was defined as all patients enrolled and received at least one dose of any drug in study treatment, which was the primary efficacy analysis set. The safety analysis set included all patients who received at least one dose of any study drug and recorded safety data after administration. Trial results are mainly analyzed using descriptive statistics. Overall survival (OS), median progression-free survival (mPFS), and duration of response (DoR) were estimated using the Kaplan-Meier method, and the 95% CI was calculated using Brookmeyer and Crowley methods. In addition, survival plots are plotted. The chi-square test was used to assess the associations between prior treatment and clinical outcomes. Statistical significance was defined as 