Objective
lower urinary tract symptoms, acute urinary retention, high-grade prostate cancers, prostate
HYPOGONADISM, PROSTATE CANCER, PROSTATE
To compare the effect of TRT vs placebo on the incidences of high-grade prostate cancers (Gleason score ≥4 + 3), any prostate cancer, acute urinary retention, invasive prostate procedures, and pharmacologic treatment for lower urinary tract symptoms in men with hypogonadism.