Introduction
NHLs, Non-Hodgkin lymphomas, malignant lymphomas, NHL
PROLIFERATION, NON-HODGKIN LYMPHOMA, NHL, TUMOR GROWTH, MALIGNANT LYMPHOMAS
Non-Hodgkin lymphomas (NHLs) comprise about 95% of the malignant lymphomas diagnosed in Japan [Phosphatidylinositol 3 kinases (PI3K) are a family of membrane-bound kinases involved in the growth and survival of healthy cells that are implicated in tumor growth and proliferation when they are dysregulated or aberrantly activated [This article describes a phase Ib/II study in Japanese patients with relapsed/refractory indolent NHL. The aims of the study were to identify the recommended dose of copanlisib in this patient group and assess the safety and antitumor activity of the copanlisib recommended dose.