Outcomes
INSULIN RESISTANCE, INSULIN RESISTANCE
The primary outcome in this study was offspring glucose metabolism at ~9 years of age, as expressed by fasting serum glucose and estimated insulin resistance. At the study visit, fasting blood samples were collected from the children between 07:30 and 09:00. The blood samples were collected by standard venepuncture in vacuum tubes and sat for 30 minutes at room temperature before centrifugation (3000g/4°C/10 minutes). Sera were aliquoted and stored at -80°C until further analyses. Sera from all children were analysed simultaneously for glucose and insulin with accredited analyses at St. Olavs Hospital (Trondheim University Hospital) in September 2021. Insulin resistance was estimated by HOMA-IR according to the formula 