Sequence generation {16a}
The order of interventions will be defined by random envelope picking of participants after successful passing of screening tests. Given three study arms (C, SD, SR), there are six different possible orders of interventions. Each order will be performed four times in an equal ratio. The first 18 participants will pick their respective assignment envelope from box A which contains all possible orders in triplicates (3:3:3:3:3:3), thus guaranteeing an equal allocation ratio until the minimum sample size is reached. The remaining participants will draw from box B, where each order is contained once (1:1:1:1:1:1).