Author contributions
JK, FON, LE, WD, and EC conceptualised the economic model; LE, WD, and EC built the model and ran the analyses. JK, VM, BH, SA reviewed the model and provided input to the clinical and economic parameters. All authors critically reviewed and revised the manuscript draughts before approving the final manuscript; JK and FON are guarantors for the cost effectiveness data. The corresponding author JK attests that all listed authors meet authorship criteria and that no others meeting the criteria have been omitted.