4. Discussion
muscle weakness, bone mass loss, fracture, osteoporosis-related diseases, Osteoporosis, disability, osteoporosis
BONE DISEASE, MUSCLE WEAKNESS, OSTEOPOROTIC FRACTURE, DISEASE, CHRONIC DISEASES, POSTMENOPAUSAL OSTEOPOROSIS, OSTEOPOROSIS, OSTEOPOROSIS
Osteoporosis (OP) is a common systemic bone disease. OP characterized by decreased bone mass and bone microstructure, Meanwhile, there were increased bone brittleness in the OP patients, which will finally lead to the prone to fracture. The incidence of osteoporosis in the elderly is relatively high. Once a hip fracture occurs, it will directly lead to an increase in disability and mortality in the elderly [Osteoporosis has become a common disease in the middle-aged and elderly population. Its incidence has increased significantly. A more effective prevention and treatment measure is urgently needed to improve the clinical prognosis of such patients. Osteoporotic fractures will bring a heavy burden to society and economy. Clinical data have suggested that patients disabled by osteoporosis-related diseases have longer hospital stays than patients with other chronic diseases, which will lead to a dramatic increase in the medical costs of osteoporosis-related diseases [Bushen Zhuanggu tablet is based on the theory of “kidney governing bone and marrow.” It is treated by nourishing the liver and kidneys, tonifying the qi and invigorating the blood, and forming prescriptions (Our study demonstrated that in group A, the effective rate was 98.33%; in group B, the effective rate was 80.00%; and in group C,the treatment effective rate was 93.33%. The treatment effective rate of group A was the highest among different study groups. This suggested that no matter Bushen Zhuanggu tablet was used alone or Bushen Zhuanggu tablet was combined with conventional regimen, the clinical effect was more significant than that of conventional regimen. This is closely related to the prescription of Bushen Zhuanggu tablet. The results of this study showed that after 6 months of treatment, the levels of Ca, P, Scr, and PTH in the three groups decreased. The levels of Ca, P, Scr, and PTH in group A were lower than those in other groups. After intervention, the lumbar spine anteroposterior BMD, the left lateral femoral neck, and Ward's triangle bone mineral density were all increased in the three groups. Among them, group A was higher than B and C groups. After 6 months' treatment, the levels of PINP and OC in the three groups were increased, while the levels of The improvement effect of muscle strength in group A was significantly better than other groups. This showed that Bushen Zhuanggu tablet combined with routine treatment could significantly promote the limb function in patients with POMP. The main reason is that Bushen Zhuanggu tablet can improve patients' calcium and phosphorus metabolism, bone metabolism, BMD, and other physiological indexes. The improvement of these indexes is closely related to the improvement of muscle strength and the recovery of limb function, which will form a series of positive chain reactions. Modern medical research shows that there is a significant correlation between bone mass loss and muscle weakness [To sum up, Bushen Zhuanggu tablet combined with conventional scheme is effective in the treatment of postmenopausal osteoporosis, which can significantly improve the BMD of patients, promote the recovery of limb function, and effectively prevent the occurrence of fracture. Bushen Zhuanggu tablet combined with conventional scheme is worthy of clinical promotion.