Introduction
cancer, cancer deaths, Colorectal cancer, CRC
CANCER, COLORECTAL CANCER
Colorectal cancer (CRC) is the third most common cancer worldwide and the second most common cause of cancer deaths.
Crosstalk between the MAPK and Wnt signaling pathways suggests that they may act together to drive progression of CRC.Here we report safety, pharmacokinetics (PK), and efficacy results from a phase Ib study to evaluate the combination of WNT974 + encorafenib + cetuximab in patients with BRAF 