2.6. Statistical Analysis
Statistical analysis performed using Statistical Package for Social Science Software for Microsoft Windows (SPSS Inc., Chicago, IL, USA), version 27.0. We checked for normality using a Shapiro–Wilk test. The mean and standard deviation or median summarized continuous variables. We used a chi-square test for categorical variable, We estimated the need of 177 participants in each group to obtain a power of 90% (type 1 error = 0.05, two tailed test, drop out 10%). 