Discussion
death, critically ill, shock, homeostasis disorders, lower systolic blood pressure, metabolic acidosis, restenosis
CRITICALLY ILL, SHOCK, PROLIFERATION, METABOLIC ACIDOSIS, EVENTS, RESTENOSIS
Nomogram is a graphic representation that consists of several lines. It is a pictorial representation of a complex mathematical formula. The numerical probability of individual clinical events can be generated by combining different prognostic variables and decisive variables [Our study found that among patients after PCI, the risk of in-hospital mortality was higher in females than in males. This was consistent with previous studies [Patients in ICU after PCI with lower systolic blood pressure, diastolic blood pressure and higher heart rate had a higher risk of in-hospital mortality. We suggested that the possible reason was that these patients were in shock or in a preshock state, and timely correction of shock or preshock might improve the prognosis of these patients. Patients in ICU who died in the hospital after PCI were more likely to be complicated with homeostasis disorders, including low bicarbonate, high potassium, and high anion gap. This suggests that metabolic acidosis was often present in patients with a high risk of death. Previous study has also shown an increased risk of death in critically ill patients with metabolic acidosis [As indicated in some studies, higher WBCs and PT and lower hemoglobin and platelet counts have been investigated as risk factors for in-hospital mortality in patients after PCI. Indeed, as suggested by Liu et al. [Our results showed that the risk of in-hospital mortality was higher in patients with non-drug-eluting stents than in patients with drug-eluting stents. Previous studies have demonstrated that drug-eluting stents perform better than non-drug-eluting stents in the prevention of neointimal proliferation, restenosis, and associated clinical events [We found that the risk of in-hospital death of patients who received IMV during hospital stay was higher than that of patients who received oxygen therapy or no oxygen treatment, which was consistent with our previous perception that patients with more severe illnesses are more likely to require mechanical ventilation [There are some points that should be considered when using nomograms. Most of the laboratory results we used were within 24 hours after admission, so we need to obtain the relevant laboratory results as soon as possible after admission. Because most patients have multiple vital sign measurements after admission, we selected the average value of multiple vital sign measurements, which also needs to be considered.There are several limitations of this study. First, the data for this study were extracted from MIMIC III, which is the database for a single center. Second, this study was a retrospective observational study, how the models identified in this study can be used for individualized evaluation and treatment of patients remains to be explored. Because of the unidentified confounding factors, the reliability of the results is lower than that of randomized, controlled clinical studies. Third, this study used data from the public database, and some of the data were not recorded. Even though we used multiple interpolation to fill in the missing data and appropriate calculation was based on this corrected data, there were still some differences from the original data. These differences might produce bias. Finally, the sample size of this study is still insufficient, and further studies may be needed.