E545D, Breast tumor
BREAST TUMOR, PIK3CA MUTATION
Breast tumor tissue samples were collected, and PIK3CA mutation status was determined by the central laboratory using the fluorescence quantitative PCR instrument (Cobas Z480) along with the PIK3CA Mutation Detection Kit (AmoyDx, Xiamen, China). This kit is specifically designed to detect the five hotspot PIK3CA mutations: H1047L, H1047R, E542K, E545K, and E545D.