Baseline characteristics
malignancy, allergy
ALLERGY, RECRUITMENT, IMMUNODEFICIENCY
The following data collected at baseline will be reported overall, by trial arm, and by whether patients were recruited before or after the pause in recruitment due to the COVID-19 pandemic:AgeSexEthnicityComorbidities: malignancy, pulmonary, gastrointestinal, neurological, cardiac, recent surgery, immunodeficiency, foreign body, allergy, endocrine, genetic, transplant, or other relevant historyRoute of admission: emergency department, inpatient ward, theatre, PICU, high-dependency unit, GP, or other hospitalDuration of symptoms: number of hours before admission to hospitalPrescribed antibiotic use during the past 14 days (including prophylactics)Initial diagnosisParticipant characteristics will be reported as frequencies and percentages, means and standard deviations, or medians and interquartile ranges, as appropriate. Baseline characteristics will be reported for all randomised participants, as well as for analysis populations as defined in the “Analysis populations” section. There will be no statistical comparison (e.g., using hypothesis tests) of baseline characteristics.