Exercise intervention
PERIPHERAL NEUROPATHY
The 12-week exercise intervention was delivered in an exercise clinic or by telehealth (online via the Internet) based on participants’ preferences. Participants undertook two supervised exercise sessions (either in-clinic or by telehealth) and one unsupervised home-based exercise session/week on non-consecutive days. All supervised exercise sessions were administered by the lead investigator (CS), an accredited exercise physiologist. Initial exercise prescription was based on each participant’s baseline functional and strength test results and choice of exercise delivery and adapted for limiting treatment-related side effects, such as peripheral neuropathy, and pre-existing comorbid conditions. Supervised exercise sessions consisted of a 5-min warm-up, 40–50 min of resistance training, as dictated by operational constraints, and 5 min of stretching to conclude the session. All exercise sessions included at least one multi-joint lower body exercise (e.g., leg press, sit-to-stand, and wall squat) and two multi-joint upper body exercises: a pull movement (e.g., seated row, rowing with an elastic band) and a push movement (e.g., chest press, push-ups on knees) (Supplementary Table 