Introduction
Gastric cancer, gastrointestinal malignancy, cancer, gastric cancer, tumour, AJCC, Cancer
GASTRIC CANCER, CANCER, GASTRIC CANCER, TUMOUR, LYMPH NODE METASTASIS, TUMOUR METASTASIS, CANCER
Gastric cancer (GC) is a complex gastrointestinal malignancy that has the fifth highest incidence of any cancer type worldwide [ELGC patients have more comorbidities, decreased physiological reserves, and poor tumour immune responses, which eventually lead to immune escape and tumour metastasis [To provide optimal therapeutic strategies for this population, the assessment of factors affecting life expectancy has become of tremendous importance. To date, the American Joint Committee on Cancer (AJCC) TNM staging system has been widely used for the assessment of risk stratification and prognosis in oncology [Given the limitations of the AJCC TNM staging system, clinical prediction models (CPMs) have become popular among oncologists and patients as risk assessment tools [Recently, nomograms for predicting lymph node metastasis or prognosis have been widely used in the field of gastric cancer. However, a nomogram for predicting the survival of elderly patients with LAGC has yet to be developed and validated. This study aimed to evaluate multiple factors influencing the survival of gastric cancer patients with LAGC based on a retrospective population-based study. Novel nomograms for predicting the overall survival (OS) and cancer-specific survival (CSS) were developed and validated. On this basis, external validation of the prediction model was carried out to demonstrate its applicability in Asian populations.