References
inflammation, tumor necrosis, keratoconus
TUMOR NECROSIS, INFLAMMATION, KERATOCONUS, OXIDATIVE STRESS, INTRAOCULAR PRESSURE
((Baseline demographic and clinical data of 34 patients with keratoconus.Ophthalmological variables at baseline and at the end of the study in patients treated with the DHA supplement and in controls.K1: flat keratometry; K2: steep keratometry; Kmax: maximum keratometry; Km: mean keratometry; CAT: corneal apex thickness; CCT: central corneal thickness; MCT: minimum corneal thickness; CA: chromatic aberration; IOP: intraocular pressure; GAT: Goldmann applanation tonometry. Data expressed as mean and standard deviation (SD).Lipidomic variables at baseline and at the end of the study in patients treated with the DHA supplement and in controls.DHA: docosahexaenoic acid; ARA: arachidonic acid; PUFA: polyunsaturated fatty acids. Data expressed as mean and standard error of the mean (SEM).Antioxidant variables at baseline and at the end of the study in patients treated with the DHA supplement and in controls.TAC: total antioxidant capacity; Cu: copper; equiv: equivalents; MDA: malondialdehyde; GSH: glutathione; GSSG: oxidized glutathione. Data expressed as mean and standard error of the mean (SEM) in parenthesis.Variables related to inflammation at baseline and at the end of the study in patients treated with the DHA supplement and in controls.IL: interleukin; TNF: tumor necrosis factor; VEGF: vascular endothelial growth factor. Data expressed as mean and standard error of the mean (SEM).Correlations between ophthalmological parameters and biomarkers of oxidative stress and inflammation in patients with keratoconus treated with DHA supplementation.GSH/GSSG ratioIL-8IL-4IL-10TNF-αGSH freeIL-6IL-10GSH totalGSH freeGSH/GSSGIL-18GSH: glutathione; GSSG: oxidized glutathione; IL: interleukin; TNF: tumor necrosis factor.