Author contributions
T.M., J.O.
PATHOLOGY
M.Z. is the corresponding author, conceptualized and designed the study, was the principal investigator of the clinical trial, coordinated data analysis and wrote and edited the manuscript. E.R.P. provided oversight for trial design and conduct, participated in data analysis and provided editorial support. K.S.C. coordinated primary correlative analysis plans, oversaw the flow cytometry analysis, and provided writing and editorial support. A.W.F. performed the flow cytometry work and analysis and provided writing and editorial support. K.C., T.M., J.O. coordinated trial activities and helped with data collection and analysis. RK oversaw trial conduct, coordinated specimen collection and analysis, provided writing and editorial support. H.B., C.S.D., E.D., D.M.G., A.J., L.M., E.O. participated in patient accrual and provided editorial support. K.D., K.R. provided statistical analysis for clinical and correlative data and provided writing and editorial support. R.K.A. oversaw collection and processing of all correlative specimens and provided data analysis. E.A.D. prepared and analyzed all pathology specimens. E.C., M.E. performed multiplex and cytokine analyses and provided data analysis support and editorial support. All authors had an opportunity to review and approve the final submitted manuscript and