Intervention and procedures
mucositis
MUCOSITIS
Patients were randomly assigned in 1:1 ratio to receive intravenous leucovorin every 6 h at either a usual (15 mg) or high-dose (25 mg), continued till hematologic recovery or for 10-days whichever was earlier. They continued to receive standard care by their treating physician, which included antibiotics, G-CSF, blood products, local analgesics for mucositis. All patients underwent daily blood counts and examination for mucositis for progression/recovery. If discharged from the hospital, patients were telephonically called up at 30-days to assess their outcome.