Primary and Secondary Outcomes at Follow-up 
Abbreviations: HRQOL, health-related quality of life; NA, not applicable.Assuming no difference between groups at baseline, the model was adjusted for randomization strata of age (<60 or ≥60 years) and treatment modality (none, adjuvant chemotherapy, or neoadjuvant chemotherapy).Higher score indicating higher symptoms.Higher score indicating better quality of life.No baseline level to take into account.Cohen 