Conclusion
In this study, a comprehensive model to diagnose axillary LNM was constructed based on clinicopathology, ultrasound, PET/CT, and PET radiomics. This model with a high sensitivity (82.86%), specificity (82.02%), and an AUC of 0.874 can achieve a non-invasive, individualized, precise, and holistic presurgical assessment of axillary LNM in BC patients. Further controlled prospective studies are needed to validate the predictive accuracy of this comprehensive model.