3.4.1. Intention-to-Treat Analysis
INSULIN RESISTANCE
Mean differences in fasting insulin and HOMA-IR between TRE plus BE vs. usual care and TRE alone vs. usual care were −1.59 (−3.34, 0.16) and −1.57 (−3.37, 0.23) for fasting insulin and −0.40 (−0.91, 0.11) and −0.47 (−1.00, 0.05) for HOMA-IR, respectively. These suggested that both TRE plus BE and TRE alone did not additionally decrease fasting insulin and insulin resistance when compared to usual care. There was also no significant difference in fasting insulin and HOMA-IR levels between TRE plus BE and TRE alone groups (