Overall MAD effects
enlargement
ENLARGEMENT
For respiratory parameters, there was significant decrease in the AHI and AHI-non-supine but no significant decrease in the AHI-supine with MAD in situ in the total group, which indicated that the MADs used in this study were less effective in reducing the AHI in supine position. As MADs used in this study allow more or less freedom of vertical opening, gravity would favor mouth opening and weaken the beneficial effects of mandibular protrusion in supine position for both MADs. A study of Milano et al. [The treatment response rate in the present study (48%) is in line with other studies reporting MAD response rate between 43 and 77% [The CSAmin increased significantly with MAD in situ in the total group. Further, the increase of CSAmin was mainly due to the enlargement in the lateral dimension, which is similar to previous studies [