Outcomes
peri-intubation adverse, hypotension, cardiac arrest
ADVERSE EVENTS, SECONDARY, CARDIAC ARREST
The primary outcome was 28-day survival. The secondary outcomes were 24-h survival, 7-day survival, early haemodynamic parameters after intubation, amount of fluid required in the first three hours, and occurrence of peri-intubation adverse events. Peri-intubation adverse events included cardiac arrest (during or immediately after intubation), failed intubation, postintubation hypotension (systolic blood pressure below 90 mmHg, or mean arterial blood pressure below 65 mmHg), and use of a vasopressor (norepinephrine, epinephrine, or dopamine) within the first 24 h after intubation. Outcomes were assessed by trained research coordinators who were unaware of treatment assignment.