Study endpoints, data collection, and laboratory analyses
SECONDARY
The primary endpoints were LDL-C and systolic and diastolic blood pressures, with additional secondary endpoints that included triglycerides, high-density lipoprotein cholesterol (HDL-C), and Lp(a). Fasting blood samples for key lipid and lipoprotein endpoints were collected in duplicate following the diet run-in period and in triplicate during the final fifth week of each diet period and were stored at −80°C. The averages of replicate measurements for the endpoints, including Lp(a), taken at the end of the AAD diet or the DASH-type diet were used for analyses. This approach allowed a new steady-state for Lp(a) as previously shown (