Author contributions
S.A.K. was the principal investigator and was involved in conception, writing and drafting of manuscript, data acquisition and searching of relevant literature. S.M.R.K. has contributed to defining the methods, follow up of patients, collection of questionnaire data and interpretation of results. S.A. assisted with entry of data, registration of trial and data analysis. UH has helped with preparing of figures and tables, managing references and revision of manuscript. Z.C. has helped in proofreading the manuscript. AS contributed to statistical analyses of acquired data. All authors read and approved the final manuscript.