Introduction
UC, IBD, Ulcerative Colitis
INFLAMMATORY BOWEL DISEASE, ULCERATIVE COLITIS
Ulcerative Colitis (UC) is a chronic inflammatory bowel disease (IBD) restricted to the mucosa of the rectum and colon [After subtotal colectomy there are four available options for patients. A reasonable option is to not proceed for further surgery and leave the rectum in place—the patient will live with a permanent ileostomy. Another option is the ileal pouch anal anastomosis (IPAA) where the rectum is removed and a pouch is created from the distal part of the ileum which is stapled or sutured to the anal canal or just above [There are no randomized controlled trials (RCT) comparing IRA to IPAA. In a decision model using a Markov simulation in comparing IRA with IPAA in UC, the former was the preferred treatment option when quality-adjusted life-years were the outcome, while higher life-years was true for the latter [