Health-related quality of life
Health-related quality of life was assessed in survivors at 1 year post randomisation using the EuroQol Five Dimension 5 Level (EQ-5D-5L) Questionnaire, which provides a description of health using five dimensions each with 5 levels of severity and a visual analogue scale (VAS).If participants returned questionnaires, or answered telephone questionnaires, with concerning mental health symptoms or expressed suicidal ideation, the patient’s response was discussed with the study chief investigator, or the patient’s general practitioner if prior permission was granted for this.