Conclusions
MDD, ideation or behavior, depressive symptoms
REMISSION
In summary, in this post hoc analysis of patients with MDD with suicidal ideation or behavior, treatment with ESK + SOC, compared to PBO + SOC, resulted in greater proportions of patients achieving remission and significantly shorter time to remission (using increasingly stringent definitions of remission incorporating depressive symptoms and severity of suicidality), as well as a significantly greater percent of time spent in remission. These findings highlight the clinical benefits of ESK treatment to address high unmet needs in adults with MDD with acute suicidality.