QoL analysis
nausea/vomiting, dyspnea, loss of appetite, constipation, fatigue, diarrhea, pain
LOSS OF APPETITE
The EORTC QLQ C30 questionnaire was filled by 100% patients at baseline and 18 (81.8%) at week 12. The absolute mean difference between QoL measures at 0 and 12 weeks showed clinically significant worsening (that is, a difference of more than 10 points) among functional (physical, emotional, role and cognitive functioning) and symptom (fatigue, nausea/vomiting, pain, dyspnea, loss of appetite, constipation, diarrhea) scales. This translated into statistically significant worsening among the emotional, loss of appetite, nausea/vomiting and fatigue parameters which have been detailed in Additional file Bar graph showing differences in various parameters of QLQ C-30 domains at 0 and 12 weeks with statistically significant worsening denoted by “ + ”