4.3. Assessing the Therapeutic Effectiveness of OncoTherad
disease or disease progression
The primary criteria used to assess treatment effectiveness comprised pathological complete response (pCR), relapse-free survival (RFS), and response duration (RD). pCR was defined as the number of patients who did not show any evidence of disease or disease progression. RFS refers to the time interval from the beginning of OncoTheradAll patients were subjected to regular follow-up consultations at the outpatient clinic of HMP to assess therapeutic effectiveness. This follow-up process encompassed histopathological assessments, urinary tract ultrasounds, cystoscopies, and laboratory examinations every three months during the first follow-up year and, subsequently, every six months during the second year (