Background
malaria, HLCs, HDN
MALARIA, DISEASE, DISEASES
The human-mosquito contact rate is an essential parameter for determining disease risk in a given area and reducing human-mosquito exposure is essential for reducing the risk of diseases such as malaria [Human landing catch set-up in the temporary structureIn response to these challenges, a variety of possible alternative, ‘exposure-free’, collection methods been developed and evaluated against HLCs to examine mosquito landing rate equivalencies under semi-field and field conditions [The HDN is a collection method that consists of a person sitting underneath two untreated nets, thereby preventing any human-mosquito contact (Fig. Human-baited double net trap structureThere are two promising tools designed to protect the user from mosquito bites. First, spatial repellents (SRs), in particular, volatile pyrethroid spatial repellents (VPSRs) work by preventing human-vector contact primarily through non-contact irritancy (also referred to as non-contact excitorepellency or spatial repellency), landing inhibition, feeding inhibition, and sublethal incapacitation [Therefore, this study hypothesizes that the utility of the HDN may differ when the collector uses interventions that act primarily through contact irritancy versus spatial repellency in the vapour phase. In a semi-field system (SFS) in Sai Yok District, Kanchanaburi Province, Thailand, this study aims to assess whether the HDN can be used as a replacement collection method for the gold standard HLC in an outdoor setting to measure the protective efficacy against 