Anti-obesity and anti-fat effects of pomegranate peel
non-alcoholic fatty liver disease, weight loss
NON-ALCOHOLIC FATTY LIVER DISEASE
The study findings suggest that pomegranate peel supplementation significantly reduces weight, body mass index, waist circumference, fat mass index, and trunk fat in patients with non-alcoholic fatty liver disease after adjusting for potential confounders and baseline values. Furthermore, in adjusted model, the pomegranate peel group showed a statistically significant decrease in fat free mass, with a mean change of -0.99 ± 2.0 kg. In comparison, the control group showed a tiny increase of 0.08 ± 2.0 kg. The decrease in the FFM in the pomegranate peel (PP) group may be due to the lack of control over all factors and confounding variables affecting FFM such as diet, physical activity, age and sex, race, and hormonal status of the individual.The study conducted by Grabez et al. [A review of changes in anthropometric indices between studies revealed conflicting results in animal studies [In our study, we observed no significant impact of the pomegranate peel extract supplement on the dietary intake of the participants. These findings align with previous investigations, such as the study by Khadem-Haghighian et al.[Although the reduction in calorie intake in the pomegranate peel group may not have reached statistical significance compared to the control group, it is noteworthy from a nutritional standpoint as it contributed to greater weight loss. Animal studies have indicated that pomegranate peel can positively affect appetite through its influence on leptin [