Participants
systemic disorders, ocular comorbidities, keratoconus
REFRACTIVE ERROR, KERATOCONUS
The subjects underwent either LASEK or FS-LASIK surgery; the choice of surgery was determined by the desire of the subject based on surgical indications. The inclusion criteria for surgery were as follows: (1) subjects were 18–45 years old; (2) has a stable refractive error for at least 2 years ( < − 0.25 D change per year); (3) the estimated residual stromal bed thickness was not less than 280 µ m; and (4) the subjects with more than a -5.00D spherical equivalent only chose FS-LASIK surgery. The exclusion criteria included topography consistent with keratoconus, eyes with ocular comorbidities, previous ophthalmic operation, relevant systemic disorders, medication history, especially growth inhibitors and glucocorticoids, pregnancy, monovision, and missing medical charts.