Statistical analysis
depression, anxiety
REGRESSION, DISORDERS, RELAPSE
The clinical outcome data were analysed and reported on both intention-to-treat (ITT) and per-protocol (PP) analysis. The ITT sample included all patients who were willing to attempt tapering. The PP sample included patients who attended at least 4 sessions of MBCT, if allocated to MBCT. We did not include the SPD intervention as criterium for the per-protocol analysis as this intervention was optional. Multilevel analyses were used to account for the hierarchical structure of the data (i.e. multiple assessments nested within patients, patients nested within practices). Multilevel logistic regression models were used to test differences in discontinuation rates between the conditions. Relapse percentages of depression or anxiety disorders were compared with a Chi