Toxicity
pneumonitis, Toxicities, fatigue, gastrointestinal adverse, toxicities, esophagitis, dermatitis
PNEUMONITIS, ESOPHAGITIS, DERMATITIS, HAND DERMATITIS
Toxicities were evaluated according to CTCAE 4.0. Hematological toxicities were much more severe in chemoradiation group from our study than that in radiation-only group in ESO-Shanghai 8 study. Similarly, fatigue and gastrointestinal adverse events were more frequent in chemoradiation group than radiation-only group. As for radiation-induced toxicities, grade 2 or more pneumonitis, esophagitis and dermatitis were also more frequent in chemoradiation group than radiation-only group (27.1% vs. 20.0% for pneumonitis, 17.1% vs. 7.1% for esophagitis, 7.1% vs. 1.4% for dermatitis, respectively). Two patients died of radiation pneumonitis in chemoradiation group (Table Acute treatment toxicitiesAcute AE were defined as occurred during or within 6 months after radiotherapy