Spatial resolved immune ‘cold’ patterns
tumor, tumors, non-IE, Tumor
TUMOR, TUMORS, COLD, TUMOR
The spatial distribution of TILs recruited into tumors after nAde was carefully examined using multiplex immunofluorescence in two poor responders (P22 and P03), both with non-IE phenotypes. We observed two types of distinct immune ‘cold’ patterns. The first was an ‘immune-excluded’ pattern in patient P22. Tumor cells gathered in a large area and there was large distance between immune cells and tumor cells. In addition, CD20