Conclusions
chronic pain, depressive symptoms, fatigue, pain
CHRONIC PAIN, RECRUITMENT
Digital pain self-management interventions, such as EPIO, delivered in a simple blended care model, may have the potential to support self-management and improve coping and psychological functioning for people living with chronic pain. Despite not showing a statistically significant impact on the primary outcome of pain interference on function after 3 months in this RCT, participants with chronic pain conditions having access to the EPIO intervention showed a statistically significant decrease in depressive symptoms and self-regulatory fatigue (ie, increased capacity to regulate thoughts, feelings, and behavior), compared with those in the care-as-usual control group. Therefore, long-term efficacy testing is warranted and in progress.The authors would like to thank the patients who participated in this study. Without them, there would be no such research. The authors would also like to thank all collaborating partners and participating health care providers for enabling recruitment and supporting this project. Finally, the authors would like to thank the research project team members, including the content development group and the design and software team at the Department of Digital Health Research at Oslo University Hospital, for their exceptional efforts throughout the project.Conflicts of Interest: LSN is an unpaid board member of dHealth AS, a company eventually aiming to commercialize the EPIO program. All other authors declare no other conflicts of interest.CONSORT-eHEALTH (Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online Telehealth) checklist (V 1.6.1).Estimates at both time points and between-group differences in the change from baseline to the 3-month follow-up.