5. Conclusions
anxiety, pain
In this randomized, double-blind, placebo-controlled trial to evaluate the effects of two formulations of sleep softgels relative to placebo, we observed that a botanical blend containing lower amounts of THC and higher amounts of GABA, hops oil, and valerian oil significantly improved sleep quality, anxiety, stress, and overall well-being in healthy individuals with a desire for better sleep. We observed no significant difference in effect on any health outcome (sleep quality, anxiety, stress, pain, or overall well-being) between a botanical blend containing higher amounts of THC and lower amounts of GABA, hops oil, and valerian oil and the placebo control. The active products demonstrated a favorable safety profile; all side effects were mild or moderate, and there were no significant differences in the frequency of reported side effects between the active arms and placebo.