Contribution of the individual components of the OBS
tachycardia, cardiovascular disease, aneurysm, cancer, stroke, diabetes, angina pectoris, atrial fibrillation, depression, hypertension, dyslipidemia
PULMONARY EMBOLISM, MYOCARDIAL INFARCTION, CARDIOVASCULAR DISEASE, ANEURYSM, CARDIOVASCULAR DISEASES, DEEP VEIN THROMBOSIS, CANCER, STROKE, RECRUITMENT, INTERMITTENT CLAUDICATION, CARDIAC INSUFFICIENCY, DIABETES, ATRIAL FIBRILLATION, EVENTS, HYPERTENSION, DYSLIPIDEMIA
After removing each of the OBS components one at a time and adjusting for the removed component using it as a covariate, the differences in mortality risk estimates remained significant and barely changed (a maximum difference of 2% with respect to the primary OBS analysis) (Fig. All-cause mortality hazard ratios (HRs) and 95% confidence intervals (CIs) per 1-point increment associated with the oxidative balance score (OBS) and after alternate subtraction of each of its dietary components. All models were adjusted for age (underlying variable), family history of cardiovascular diseases (dichotomous), following special diet at baseline (dichotomous), marital status (married, single and others). Mediterranean adherence (continuous), prevalent cancer (dichotomous), prevalent depression (dichotomous), prevalent cardiovascular disease* (dichotomous), prevalent diabetes (dichotomous), prevalent dyslipidemia (dichotomous), prevalent hypertension (dichotomous), sex (dichotomous), total energy intake (continuous), use of aspirin (dichotomous), years of higher education (continuous), corresponding subtracted component, and stratified by deciles of age and recruitment period (6 categories). *Prevalent cardiovascular disease was considered as having at least one of the following events before entering the cohort: aneurysm, angina pectoris, atrial fibrillation, cardiac insufficiency, coronary bypass, deep vein thrombosis, intermittent claudication, myocardial infarction, pulmonary embolism, stroke, or tachycardia