Secondary Outcomes
Secondary outcomes included MoCA assessment at 24 weeks and other cognitive subdomain tests and blood metabolic indices measured at 24 and 36 weeks. Cognitive subdomain tests included the Wechsler Memory Quotient (MQ), Digit Symbol Substitution Test (DSST), Trail-Making Test, part B (TMT-B), Boston Naming Test (BNT), and Rey-Osterrieth Complex Figure Test (ROCF). Participants were asked to fast overnight and had their venous blood drawn on an empty stomach the next morning. Serum levels of fasting glucose, insulin, glycated hemoglobin (HbA