Pharmacokinetic-pharmacodynamic target attainment analyses.
PK-PD, CABP
PK-PD target attainment analyses were performed using R version 3.3.1 (Percent probabilities of PK-PD target attainment by MIC on the above-described days of assessment were compared to the observed percentage of successful clinical responses by MIC among omadacycline-treated patients with CABP and Percent probabilities of PK-PD target attainment were also assessed weighted over omadacycline MIC distributions for 1,314 Emphasis was placed on the PK-PD target attainment results based on total-drug ELF AUC/MIC ratio targets associated with a 1-log