Evaluation of outcomes
death, Tumour, Cancer
DISEASE PROGRESSION, ADVERSE EVENT, TUMOUR, DISEASE, ADVERSE EVENT, CANCER
PFS is defined as the time from randomisation to disease progression or death from any cause. OS is defined as the time from randomisation to death from any cause. Tumour response is assessed according to the RECIST (version 1.1). Objective response rate (ORR) is defined as the proportion of patients with a complete response or partial response to treatment. DCR is defined as the proportion of patients with a complete response, partial response, or stable disease. The severity of each adverse event is graded according to the National Cancer Institute Common Terminology Criteria for Adverse Events (version 5.0).