Ethics approval and consent to participate
HEART, -11
The study design was approved by the Institutional Review Boards of the Hallym University Chuncheon Sacred Heart Hospital (IRB no. 2021-11-002), Wonju Severance Christian Hospital (IRB no. CR121091), Gangneung Asan Hospital (IRB no. GNAH 2022-01-002), and Kangwon National University Hospital (IRB no. 2021-09-014). This trial was registered at the Clinical Research Information Service (criskorea@korea.kr, KCT0006749) and conducted in accordance with the Declaration of Helsinki. The study protocol followed the CONSORT guidelines. Written informed consent was obtained from each participant before the administration of any study drug.