Changes in specific bacterial taxa
For identify the changes in specific bacterial taxa after prebiotics supplemented intervention. We utilized the linear discriminant analysis (LDA) effect size (LEfSe) to compare the gut microbiota composition between placebo and GOS groups. The LDA score was selected to discriminate specific taxa in two groups. Compared with the placebo group, the GOS group had a higher abundance of Identification of the most differentially abundant analyzed by the LEfSe method. 