Humoral immunogenicity
POLIO
As a full polio immunization history with IPV was required for participation, the seropositivity status in the 77 per protocol participants at baseline was high; seropositivity rates were 97.4%, 93.5% and 97.4% for polio types 1, 2, and 3, respectively, and >90% in individual study groups (Type-specific humoral neutralizing antibodies (per protocol population).a. Geometric mean-fold rise and confidence interval computed via the maximum likelihood method on the difference in logb. ≥4-fold increase in serum neutralizing activity from baseline or post-vaccination reciprocal titer ≥ 1:8 if seronegative at baseline.