Statistical analysis
REGRESSION
Statistical analyses were performed using IBM SPSS Statistics software version 25.0. Continuous data with a normal distribution are reported as means ± standard deviations. Hypotheses on the mean differences between groups were tested using the independent samples t-test or analysis of variance. The median and interquartile range were used to represent non-normally distributed continuous data, and the rank sum test was used for comparison between groups. Categorical data are reported as numbers and percentages. Relationships between categorical variables were analysed using Fisher’s exact or Pearson’s chi-squared test. Multiple logistic regression analyses were performed on variables that were considered clinically significant and with a 