Introduction
conjunctival, SCC, CIN lesions, corneal squamous epithelial tumors, OSSN, CIN
SQUAMOUS CELL CARCINOMA, OCULAR SURFACE SQUAMOUS NEOPLASIA, CONJUNCTIVAL INTRAEPITHELIAL NEOPLASIA, CIN
Ocular surface squamous neoplasia (OSSN) is a clinical term that denotes a range of conjunctival and corneal squamous epithelial tumors, including conjunctival intraepithelial neoplasia (CIN) and invasive squamous cell carcinoma (SCC) [The classical treatment for CIN lesions is surgical excision, followed by cryotherapy. Despite of the immediate and apparent success of the surgical treatment, CIN reemerges with a rate between 9 and 52% [Studies comparing the efficacy of different topical chemotherapy agents as the primary treatment of CIN are limited. With this in mind, the objective of the present study was to compare the long-term efficacy and safety of topical IFNα2b and MMC as primary therapies for the treatment of CIN.