Introduction
pulmonary embolism, Pulmonary Embolism, RV dysfunction
PULMONARY EMBOLISM, PULMONARY EMBOLISM, PATHOPHYSIOLOGY
Impairment of right ventricular (RV) function resulting from acute RV pressure overload plays a critical role in the pathophysiology and prognosis of pulmonary embolism (PE) [Among survivors of the acute phase of PE, approximately 20% have been reported to present with persistent RV dysfunction at follow-up [The prospective multicentre single-arm Pulmonary Embolism International Trial (PEITHO)-2 (ClinicalTrials.gov Identifier NCT02596555, EudraCT Identifier 2015-001830-12) investigated if the early switch from parenteral heparin to oral anticoagulation using dabigatran in patients with intermediate-risk PE is effective and safe [