External validation
The model to predict all-cause mortality was then externally validated in all AF patients participating in the ALL-IN study, both those who received integrated care as well as those who received usual care. The complete follow-up period of two years was used for external validation. To assess the predictive performance of the model in the ALL-IN trial, calibration was determined by creating a calibration plot. Discrimination was assessed by calculating Uno’s c-statistic with 95% CI.