Assessment of attention and cognitive control
medication-induced, ADHD
A standardized CPT was administered to children with ADHD outside the MRI scanner under both methylphenidate and placebo conditions. The task consisted of a Go/NoGo paradigm in which children were presented with either a target or non-target stimulus on the screen for 100 msec, once every 2 s for 15 min across three 5-minute blocks. The target stimulus was a triangle, while the non-target stimulus was either a circle or a square. Children were required to press a button when a target stimulus was presented, and withhold response to non-targets. The test performance has been normalized to age-adjusted T-scores. IIRV was quantified using reaction time (RT) and standard deviation (RTSD) from correct Go trials. We examined medication-induced performance differences using paired 