Discussion
PFAPA
DISEASE
PFAPA was reported to be a sporadic disease. In recent years, however, there have been increasing numbers of studies that have recorded a positive family history in first-degree relatives of patients with PFAPA. It was first documented by case report series (Clinical symptoms of PFAPA (comparison of studies).According to the available data, a single dose of prednisone (1–2 mg/kg) or betamethasone (0.1–0.2 mg/kg) administered at the beginning of an attack leads to a rapid termination of the attack within a few hours (