Statistical analysis
depression, anxiety
Statistical analysis was performed using SPSS version 24. The normality of the quantitative data was assessed using the Kolmogorov-Smirnov (K-S) test. Independent t tests, chi-square, chi-square by trend and Fisher’s exact tests were used to assess the homogeneity of the study groups. To compare the groups in terms of mean scores of anxiety, depression, and quality of life, independent t-test was performed before the intervention and ANCOVA test after the intervention by adjusting baseline values. All analyses were performed based on Intention-to-Treat by including all randomized patients in the analysis, regardless of what intervention they received. P < 0.05 was considered significant.