Correlation between bacteriology and mood state
In order to investigate the relationships between changes in gut microbiota taxa and mood state we constructed a correlation matrix using the fold change ((post-pre)/pre)) for the entire cohort of the QMP bacterial taxa and mood state data. The data were then analyzed using a nonparametric Spearman’s rank correlation corrected using FDR (Bacterial taxa-taxa interactions from the entire cohort. Pairwise correlations between bacterial taxa fold change data were calculated using a Spearman’s rank correlation (2-sided adjusted using FDR). Taxa-taxa correlations ranged from -1 to 1 (negative to positive). The depth of the color represents the strength of the correlation. Adjusted Bacterial taxa-mood state interactions from the entire cohort. Pairwise correlations between bacterial taxa and mood state fold change data were calculated using a Spearman’s rank correlation (2-sided adjusted using FDR). Taxa-mood state correlations ranged from -1 to 1 (negative to positive). The depth of the color represents the strength of the correlation. Adjusted We observed several significant correlations between both taxa-taxa and taxa-mood state. Regarding taxa-taxa interactions, Regarding taxa-mood state interactions, significant negative correlations were found between 