Introduction
HTN, hypertension
HYPERTENSION, DISEASES, CARDIOVASCULAR DISEASE, HTN
In recent years, the prevalence of hypertension (HTN) has increased worldwide, especially in low-income countries [HTN is usually diagnosed by measurement of blood pressure by health professionals; However, because of variations in blood pressure, observer bias, and use of nonstandardized devices, HTN may be underdiagnosed [Metabolomics has evolved significantly over the years and can now provide us with enormous and valuable data useful for understanding a detailed mechanism in the development of many diseases, including cardiovascular disease. Metabolomics is also emerging as a method for identifying new biomarkers for early diagnosis [It is suggested that disturbances in branched-chain amino acids, urea cycle products (arginine and citrulline), and acylcarnitines may play an important role in cardiovascular disease [