Introduction
death, melanoma
DISEASE, MELANOMA
Surgical treatment is effective for early-stage melanoma, but patients with resected advanced disease have a high risk of relapse. Recent clinical evaluation of immune checkpoint blockade in this adjuvant setting has shown a significant reduction of the relative risk of death [We recently tested the feasibility and safety of dendritic cell (DC)-based vaccines in high-risk melanoma patients, where the cells were loaded with long NY-ESO-1 peptides designed to give good population coverage on the diverse HLA polymorphism of the human population [