Introduction
Heart failure, heart failure, cardiovascular death
HEART FAILURE, HEART FAILURE, TYPE 2 DIABETES
Heart failure with reduced ejection fraction (HFrEF) is a type of heart failure in which the ejection fraction is less than 40%. HFrEF poses a considerable challenge to public health that affects millions of people worldwide. A survey of Chinese heart failure patients found that HFrEF accounted for 39.7% of all heart failure patients [Research has shown that HFrEF and type 2 diabetes often coexist [SGLT-2 inhibitors were initially formulated for the management of type 2 diabetes, constituting a category of medications, but recent studies have shown their potential benefit in HFrEF. Among the SGLT-2 inhibitors investigated in HFrEF, dapagliflozin has been subjected to extensive research, and it has been shown to reduce the risk of heart failure hospitalization and cardiovascular death in patients with HFrEF [