Selection and refinement of intervention components
obesity, weight gain, overweight or obesity
OBESITY
Findings from the optimization trial will be used to refine and select intervention components. Following approaches described by Kugler et al.,Although child BMI change was not a primary study outcome, it would be prudent to estimate the combined effects of each component on children’s pre–post change in BMI and conditional weight gain, specifically for children with overweight or obesity at baseline. Findings from a meta-analysis of interventions with a parent component designed to reduce obesity in early childhood showed that short-term effects on children’s BMI outcomes were small (To date, few obesity prevention or intervention studies have been designed using MOST. At the time of submission of this manuscript, a search of the literature using the terms “multiphase optimization strategy” and “obesity” yielded 12 published papers describing the design of or results from obesity prevention or intervention studies using the MOST framework. Of these 12 published papers, three described studies targeting preschoolers or parents of preschoolers,