Clinical significance
With available literature evidence, our present study is the first of its kind to formulate a topical gel with purslane to treat symptomatic OLP. Our study had a longer follow-up of 3 months compared to other studies in the literature. Additionally, the results were compared as intergroup and intragroup comparisons at all five time periods. Intragroup comparison of all the groups at five different periods showed that both 5% and 10% topical purslane gel showed significant efficacy compared to the gold standard, making it a reliable treatment option.