Risk stratification for elderly patients with EOC
tumor
TUMOR
Furthermore, total scores were calculated according to the nomogram for risk stratification. Elderly patients with EOC were therefore classified into three risk groups for the prediction of OS, including low-risk (total points ≤ 140.91), medium-risk (140.94 ≤ total points ≤ 177.33), and high-risk (total points ≥ 177.35). Kaplan–Meier curves showed a statistically discriminatory for all three subgroups in both training and validation groups, whereas the AJCC stage system had shown inadequate ability to distinguish mortality risk, especially in stage III and stage IV, similarly in stage I and stage II (Figs. Kaplan–Meier curves of elderly patients with EOC for predicting OS. Kaplan–Meier CSS curves of elderly patients with EOC based on the new risk stratification system and the AJCC stage system. In addition, surgery and chemotherapy were both independent prognostic factors in elderly patients with EOC, we attempt to clarify the efficacy of treatment including surgery and chemotherapy in the above three risk stratification subgroups by log-rank test and Kaplan–Meier curves. According to our results, elderly patients with EOC undergoing local tumor resection had a higher survival rate compared with debulking as well as pelvic exenteration (Fig. Kaplan–Meier curves for predicting OS based on the new risk stratification system of all elderly EOC patients. Kaplan–Meier OS curves of patients with various surgery types in the low- (Kaplan–Meier CSS curves for all elderly EOC patients based on the new risk stratification system. Kaplan–Meier CSS curves of patients with various surgery types in the low- (