Study design
Projecte Moviment is a multi-center, single-blind, proof-of-concept RCT recruiting healthy low active late-middle-aged adults to be assigned in a four parallel-group design including 12-week intervention programs. Participants were assessed at baseline and at trial completion and randomly assigned to an AE group, a CCT group, a COMB group, and a waitlist control group. The study was developed by the University of Barcelona in collaboration with Institut Universitari d’Investigació en Atenció Primària Jordi Gol, Hospital Germans Trias i Pujol and Institut Guttmann and approved by the responsible ethics committees (Bioethics Commission of the University of Barcelona — IRB00003099 — and Clinical Research Ethics Committee of IDIAP Jordi Gol — P16/181) following the Declaration of Helsinki. The study took place between November 2015 and April 2018.This research paper follows the previously registered (ClinicalTrials.gov; NCT031123900) and published protocol [