Data management
CRF
CRF
Investigators will enter the data required by the protocol into the case report forms (CRF). The principal investigator is responsible for assuring that data entered into the CRF is complete and accurate, and that entry is performed in a timely manner. The signature of the investigator will attest to the accuracy of the data on each CRF. All data management activities will be completed prior to the final closure of the database.