Discussion
intraventricular conduction abnormalities, HAVB, diabetes mellitus, TAVR, aortic stenosis, PPM
AORTIC STENOSIS, DIABETES MELLITUS, CONDUCTION DISTURBANCE
Transcatheter AVR has been shown to reduce morbidity and mortality in patients with severe aortic stenosis but can cause intraventricular conduction abnormalities. The value of measuring the HVi before and after TAVR for prediction of future conduction disturbances was unknown. The main findings of our study are: (1) significant HVi prolongation post TAVR did not indicate a higher risk for progression rate to HAVB during 30 days post TAVR, (2) pre-existing BBB, a new-onset left BBB after TAVR, and diabetes mellitus were independent predictors for development of a HAVB requiring PPM after TAVR, (3) other known risk factors could not be verified as predictors for HAVB post TAVR in our study, and (4) there were no differences neither in the occurrence of HAVB requiring PPM nor occurrence of ICA between the self-expandable and balloon-expandable valves.