Patients
HER2-negative, tumor, tumors
DISEASE, TUMOR, TUMORS
Eligible patients were adults according to local regulations and had CLDN18.2-positive (defined as ≥75% of tumor cells with moderate-to-strong membranous CLDN18 staining as determined by central immunohistochemistry using the investigational VENTANA CLDN18 (43-14A) RxDx Assay), HER2-negative (per local or central testing), previously untreated, locally advanced unresectable or mG/GEJ tumors with radiologically evaluable disease according to RECIST version 1.1. Patients had an ECOG performance status score of 0 or 1 and adequate organ function. Full inclusion and exclusion criteria are as follows: