Subject elimination criteria
Subjects can voluntarily withdraw from the trial at any time for any reason, and the investigator can also suspend any subject from participating in the trial for various reasons (mainly including safety issues or breach of protocol). Subjects who have one of the following circumstances shall withdraw from the trial or be deemed to have withdrawn from the trial:① The subjects stopped taking the drug on their own and were unwilling to continue the trial due to poor efficacy or ineffectiveness;② Subjects withdraw their ICF and voluntarily withdraw from the trial;③ Subjects are lost to follow-up.