Conclusions
ROP
This cohort study of 17 preterm neonates provides evidence that RBC transfusions from adult donors may be associated with more oxygen delivery to cerebral tissues of preterm neonates than transfusions from CB. This finding may help explain the previously observed connection between low HbF and high ROP risk. It also suggests that use of CB to meet the RBC transfusion needs of neonates with a gestational age of less than 28 weeks may protect cerebral tissues from overexposure to oxygen.