4. Discussion
infection, infections
INFECTION, COMMON COLD, INFECTIONS
In the previous study, we reported that the intake of yogurt containing LG2055 suppressed the subjective symptoms of the common cold in healthy adults [Next, we performed a clinical trial and found that the LG2055 group showed significantly lower ratios of cumulative days of several local and systemic symptoms than the placebo group (In this study, the secretion rate of salivary sIgA was used to select immune-weakened participants. Salivary sIgA is known to bind to various pathogenic organisms and prevent host infections [Sugimura et al. reported that Activated pDCs are known to produce type I interferon, activate various immune cells, such as NK, B, and T cells, and strengthen the host’s immune system, thus, activated pDCs are considered to contribute to the prevention of infection [pDCs have been suggested to take up LAB and recognize bacterial DNA via TLR9 [We used a physical health questionnaire survey to assess the primary outcome of this study. As expected, the incidence of many symptoms was reduced in the LG2055 group (LG2055 has been reported to act as a probiotic and to improve the intestinal environment [On the basis of the bacteriological composition, the human gut microbiota can be classified into several groups (enterotypes). Enterotypes are traditionally categorized as 