Study setting (Conceptual framework)
SECONDARY, COMPLICATIONS
In this study the primary outcomes was knowledge, construct of TPB (Attitude, Subjective norm, Perceived behavior control, Intention) and secondary outcome was treatment adherence behavior's.The pre-test was administered to both groups based on the questionnaire. The intervention group received trainings based on TPB and the control group received routine cares. Then the patient were followed up for three months. After that the post-test was administrated and finally the effect of education on treatment adherence in patients with MS receiving injectable immunomodulatory drugs was re-evaluated.According to the similar study and panel of experts, three months of follow-up was considered sufficient time to establish consistency, stability, and sustainability in treatment adherence in patient with MS receiving injectable immunomodulatory drugs [The conceptual framework of conducting this study was that according to the study criteria, the samples were selected by referring to the MS clinic and divided into control and intervention groups. Then pretest was administered to both groups based on the questionnaire and the intervention group received training based on the TPB.By utilizing the attitude construct, patients are firstly exposed to non adherence drugs problem and understand the complications and at the same time they are taught the consequence for advantage and disadvantage of treatment adherence drugs. Then by utilizing the subjective norm and increasing patients' perceived behavior control, they were taught behaviors related to treatment adherence drugs. The control group also received routine MS clinic training. Then the patients were followed for three months and then posttest was administrated and the effect of education on their treatment adherence drugs was re-evaluated.Figure Flow diagram of the participants. From a total of 3000 MS patients referring to MS clinic, 100 were selected with systematic sampling based on the inclusion criteria and then randomly divided into intervention and control groups (50 each). In both groups, pre-test was administrated and then the intervention group received TPB based education and the control group received routine training. Three months later, post-test was administrated in both groups and treatment adherences drugs were compared in both groups