Early trials on de-escalation of axillary surgery
breast cancer
SENTINEL LYMPH NODE, BREAST CANCER
The first investigations regarding the omission of ALND were undertaken by Fisher et al. in the North-American NSABP-04 trial [Landmark trials informing the de-escalation of axillary surgery in breast cancer patients.LN – lymph node, SLN – sentinel lymph node, SLNB – sentinel lymph node biopsy; CI – confidence interval; RNI – Regional nodal irradiation; ART – axillary radiotherapy; n.A. – not available.