Methods
malaria
MALARIA
The study design and methodology for the parent clinical trial have been published previously [Study participants were recruited from two sites in Malawi: Ndirande research clinic in Blantyre, an urban centre, and Tisungane ART clinic at Zomba Central Hospital, located in a more rural setting. Of note, the two sites have different malaria burdens: malaria parasite prevalence in children under 5 years old is 4% in Ndirande versus 28% in Zomba [