Long-term follow-up
Barrett
BARRETT
Long-term follow-up was defined as an endoscopy examination more than 12 months after the last ablation.Seventy-seven patients received long-term follow-up examinations after 12–24 months, with a median follow-up period of 21.0 months (CI 19.2–22.7 months). However, only 26.7% (23/86) of the study population patients followed the complete study as per protocol, which means surveillance 3, 6, 12 and 24 months after the last therapy.After RFA, eight patients 25.8% (8/31) had histologically confirmed residual Barrett’s mucosa at the long-term follow-up examination, in comparison with 17.1% (7/41) with positive biopsy findings after H-APC. Ten patients with long-term endoscopy follow-up showed macroscopically minimal residual Barrett’s at the neo-Z line, but had negative histology findings. These patients were counted as eradicated for Barrett.In summary, the Barrett’s eradication rate during the long-term follow-up was 74.2% (23/31) in the RFA arm and 82.9% (34/41) in the H-APC arm (Fig. The flow chart shows treatments and follow-up examinations after randomisation for all patients. 