2.2. Study Population
SYSTEMIC DISEASE
The inclusion criteria were child (1) AD patients with SCORAD index > 25 and meeting the Hanifin and Rajka criteria, (2) aged 8–16 years old, with a (3) total serum IgE level > 100 IU/mL and a (4) healthy weight (5th–85th percentile) based on the CDC BMI-for-age (2–20 years old) growth chart. Patients with the following criteria were excluded: (1) treated with steroids, systemic antihistamine, or phototherapy in the last month and systemic immunosuppressive therapy in the last three months, (2) obtained a systemic antibiotic in the last one month, (3) used topical antibiotic or antiseptic soap in the last two weeks, (4) had immunosuppressive or systemic diseases, and (5) had positive feces identification for intestinal nematode parasites (e.g., 