Blood and Urine Samples
Peripheral venous blood samples
BLOOD, DECAY
Peripheral venous blood samples were taken before injection of the compound and at 2, 5, 10, 40, 60, 85, 120, and 180 min after injection. Urine samples were collected at 35 ± 10, 80 ± 10, and 180 ± 10 min after injection. An additional blood sample was collected at least 3 mo after injection and stored, together with a sample before injection, for future antidrug antibody detection (Whole-blood and plasma samples were counted against appropriate standards of known dilution in an automatic γ-well counter and, after correction for decay and background activity, expressed as percentage injected activity. Blood volume was estimated according to body weight and height using the Nadler formula and the patient’s hematocrit (