2.1. Subjects
obesity, metabolic disease
OBESITY, METABOLIC DISEASE
This study was approved by the Research Ethics Committee of Dongguk University (DGU IRB 20200033-1). We included 16 middle-aged women (age > 40 years) with obesity (>30% body fat) and without any previous diagnosis of metabolic disease or other health problems. The participants did not perform any regular physical activity or exercise. The participants were informed of the procedures and signed a document of informed consent before participating. They were instructed to maintain their typical diet pattern throughout the study, and compliance with this instruction was assessed using food questionnaires (1-day recall). The typical diet was based on the daily recommended calorie intake of 2000 kcal for Korean women and comprised foods commonly consumed by Koreans; expert feedback on the diet was provided. The participants were randomly assigned to the resistance and moderate aerobic exercise (RME, 50% VO