Author contributions
BMM contributed to research idea, study design, dataacquisition, and interpretation, drafted and critically revised the manuscript.SD contributed to study design, data interpretation, and critically revised the manuscript. MAMM contributed to study design, patients’ selection, data analysis and critically revised the manuscript. LAH made the Omega-3 gel formulation and characterization and critically revised the manuscript. MAM contributed to the microbiological part of the study and critically revised the manuscript. NMA made the statistical work and critically revised the manuscript. All authors reviewed the manuscript.