A three-dimensional plot showing metabolomic data structure for subjects in each clinical outcome measure.
SEPARATION
Principal component analysis (PCA) shows intergroup separation is shown on the X axis and intra-group variability on the Y axis based on serum metabolite and lipid profiles. Treatment responsive subjects are represented in cyan blue and treatment non-responsive subjects are represented in purple in each plot. (Differentially abundant metabolites and lipids between the outcome measures were visualized using volcano plots (