End Points
RECURRENCE
The primary end point was IBTR, which was evaluated at 6-month intervals over 5 years by history and physical examination and diagnostic breast imaging. In cases of abnormal imaging findings or discordance, biopsies were performed to evaluate for recurrence.Secondary end points included PROs from 3 validated PROMs: (1) the Decision Regret Scale (DRS), a 5-item questionnaire that assesses the extent of regret and comfort associated with a specific decision