METHODS
PIAN
This open‐label pilot study was undertaken in the Pian Center of Shanghai Changhai Hospital, China, from February 1, 2020 to January 30, 2022. The protocol is in accordance with the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) statement. This trial was prospectively registered at Chictr.org.cn with ID number ChiCTR1900025416. All participants provided written consent, and approval for the study was obtained from the Ethics Committee of Changhai Hospital (CHEC2019‐113).