Conclusions
illness, ARDS
ARDS
In conclusion, absolute values of cholesterol are low in these two ARDS cohorts, and the lowest levels of cholesterol are associated with greater severity of illness. There were differential effects of rosuvastatin and simvastatin in ARDS subjects with low cholesterol. We found rosuvastatin was associated with higher mortality in this subgroup, though simvastatin seems safe in these patients. Patients with low total cholesterol should be included in future trials of simvastatin as a treatment in ARDS.