Statistics
For statistical analyses IBM SPSS Statistics 27 was used. In order to evaluate normality of the data, all variables have been tested using the Shapiro-Wilk-test and by visually inspecting boxplots and QQ-plots. To analyze correlations between variables related to CBMN parameters at baseline, Pearson correlation and Spearman rank correlation was used. Since some parameters were not normally distributed, non-parametric tests were opted for to assess the intervention effects. The main differences between the time points were measured using the Friedman-Test. To measure baseline group differences, Mann-Whitney 