Statistical analysis
The rate of change of the quantitative variable will be calculated by subtracting the initial value from the final value and dividing the result by the initial value. Missing values will not be replaced with other values. All efficacy analyses will be conducted using the intention-to-treat and per-protocol sets. The percentage of patients with a reduction of at least 10% or 5 points in the FACT-Taxane NTX score after using either two normal-sized gloves on both hands (intervention) or nothing (control) will be compared using a chi-square test. In addition, for each variable (including the FACT-Taxane score), the percentage change after 12 weeks of using two normal-sized gloves on both hands or nothing will be analyzed. The demographic characteristics of patients wearing either two normal-sized gloves on both hands (intervention) or nothing (control) will be summarized using the mean (standard deviation) for continuous data by group and count (percentage) for categorical data. Comparisons between the treatment groups will be performed using the chi-square test (categorical variables) and two-sample t-tests (continuous variables). All statistical analyses will be performed using the STATA software (version 16.0; StataCorp LP, College Station, TX, USA). 