Statistical analysis
postoperative agitation
We calculated the sample size for the primary analysis on the basis of differences seen in the previous study. In the study about reducing postoperative agitation in patients undergoing functional endoscopic sinus surgery (FESS), the difference in RASS scores between two groups was 1 to 2 during the observation period.Data are expressed as the mean±SD or median [IQR] for non-normally distributed variables (Kolmogorov–Smirnov test), or number and percentage as appropriate. All statistical test were performed two sided. All analyses were performed by EZR version 1.52 (Saitama Medical Centre, Jichi Medical University, Saitama, Japan), which is a graphical interface for R version 4.02 (The R Foundation for Statistical Computing, Vienna, Austria). More precisely, it is a modified version of R commander designed to add statistical functions frequently used in biostatistics [