Procedures
prebreakfast self‐measured blood glucose, diabetes, hypoglycaemia
ADVERSE EVENTS, DIABETES, HYPOGLYCAEMIA
At BV, previous insulin treatment was discontinued and once daily IDegLira was started at any time, independent of meals, repeated approximately at the same time each day. The vast majority of the patients administered IDegLira in the morning, before breakfast. The starting dose of IDegLira was 16 dosage units (each dosage unit contains 1 unit of insulin degludec and 0.036 mg of liraglutide). Patients were advised to titrate IDegLira every 3 days with 2 units to achieve a prebreakfast self‐measured blood glucose (SMBG) range of 5–6 mmol/L.Metformin was initiated or continued and titrated up with 500 mg weekly to 3000 mg or to the maximal tolerated dose.Patients were instructed to test blood glucose daily (at least once before breakfast and at any time when symptoms of hypoglycaemia occurred) with their own glucometer and to record their readings into their diary.An early control (Visit 0) was performed 14 days after BV to check self‐titration and adverse events. Patients were followed during the routine diabetes care. Data were collected by the study staff at baseline and during the scheduled clinical visits performed 3, 7 and 12 months (Visits 1, 2 and 3, respectively) after BV.