Introduction
Acne vulgaris, acne
SCARRING, ACNE VULGARIS, ACNE, ACNE VULGARIS
Acne vulgaris is one of the main reasons for dermatological consultation with substantial physical and psychosocial burden [Numerous laser devices were proven successful in acne therapy, as they provide an efficient treatment of acne with a short recovery period and fewer drawbacks, notably the Nd:YAG laser, which has been documented with several studies [The mechanism of action of 1064-nm Nd:YAG laser relies on its action on the vascular element of inflammatory acne together with the alteration of cytokine release. While the improvement of non-inflammatory lesions can be attributed to the thermal damage to sebaceous glands causing sebum reduction [Fractional CO2 laser has been established as one of the best options of acne scarring therapy. Although, it can be hypothesized that fractional CO2 ablative laser can be a proper modality for inflammatory acne vulgaris, based on its effects on the various mechanisms of acne production [As, fractional COThere is limited evidence and few studies about benefits of fractional CO2 lasers for treating inflammatory acne. Consequently, the current trial aimed to asses efficacy and safety of fractional CO