Sequence assembly
Sequencing resulted in an average of 21.7 ± 3.5 M reads per WGS sample (median: 22.4 M reads), and 23.6 ± 18.3 M per VLP sample (median: 18.1 M reads). Before assembly, reads belonging to the same participant were concatenated. Adapter sequence removal and read trimming were performed with fastp v0.23.2 (option –detect_adapter_for_pe)