Primary and secondary outcomes
REGRESSION, SECONDARY
Findings did not demonstrate any significant difference in SIRI-2 scores between ESG and DSG before crossover was applied (Similar to SIRI, no significant difference was observed in any of the secondary outcomes between ESG and DSG before or after the crossover of The effects of time by group (ESG/DSG) on the study’s outcome measures. The graphs display the time (T0/T1/T2) by group (ESG/DSG) interaction on the study’s outcome measures, using the random-effects regression model. Errors bars are reported at a 95% confidence interval. Despite the medium and large attrition rates at the end of periods 1 (28%) and 2 (40%), there was no difference between the effect sizes resulting from the ITT approach on any of the outcome measures (primary or secondary) compared to those of the mixed model analysis without any ad-hoc imputation (per-protocol analysis).