Limitations
There are a number of limitations to this study. Despite the large sample size compared to other studies, a larger sample size would be needed to be powered for effects that are smaller but still relevant. Some of the data (4%) could not be analysed because it was not labelled with the participant and timepoint. The COVID-19 pandemic started in the middle of the study, might have added noise to the data, and meant that we had to switch from in-person cognitive testing to testing via video call. However, we do not see this potential source of noise reflected in the standard deviations compared to pre-pandemic studies. We assessed baseline days per week of meat consumption (median = 3.5, mean = 3.7, SD = 2.0), but not grammes per day of consumption. However, creatine intake through meat is usually substantially lower than the supplemented dose [