Data collection
COPD, overdosed
COPD
ADR cases with a prior diagnosis of COPD (ICD-10: J44) were extracted from the ADRED data, irrespective of the reason of presentation to the ED. Hence, all cases documented presented with an at least possible ADR. From these cases, demographic and general clinical data such as current medication use, previous diagnoses, severity of COPD using the GOLD classification [All cases included in the analysis were assessed for the use of inhaled therapies. Inhaled therapy was defined as the use of long-acting β-agonists (LABA), long-acting muscarinic antagonists (LAMA), short-acting β-agonists (SABA), short-acting muscarinic antagonists (SAMA), or inhaled glucocorticoids (ICS). In the case of prescribed inhaled therapy, the frequencies of use and dose were analyzed for conformity to drug labels and guideline recommendations [All documented ADR in the COPD group with overdosed inhaled therapy (Table 