Study administration and management
APPENDIX
The local Institutional Review Board or Ethics Committee at each participating co‐center must approve the study, and all patients must provide written informed consent before enrollment. Funding will be provided by the Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University for the co‐centers. The First Affiliated Hospital of Nanjing Medical University will preserve the complete study database and perform all key analyses. The Steering Committee, independent Data Safety Monitoring Board (DSMB), and ERC have been set for the safety control and the evaluation of the primary endpoints (see Supporting Information: Appendix 