Study design
AMS
RECRUITMENT
This randomized, double-blind, placebo-controlled, parallel trial evaluating the efficacy of preventive acetazolamide treatment on visuomotor performance in healthy middle-aged lowlanders during a stay at high altitude. Data were collected from June to July 2018, with recruitment and baseline data collection being carried out at 760 m in a university clinic (National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan) and subsequent measurements at high altitude being held at a high altitude clinic (Too Ashu, Kyrgyzstan) at 3,100 m.This study was part of a larger trial investigating the effect of acetazolamide on the prevention of AMS in healthy individuals older than 40 years. Baseline characteristics as well as data on clinical outcomes and AMS have been reported previously [