Analyses by Genetic Subgroup: mtDNA vs nDNA
SE
mtDNA: Subgroup analysis for participants with mtDNA alteration of the 6MWT at the end of treatment showed the LS mean (SE) of change from baseline in distance walked at week 24 was 14.0 (±6.1) meters for participants receiving elamipretide (n = 74) and 25.0 (±6.1) meters for participants receiving placebo (n = 79), an −11.0-meter between-group difference favoring placebo (95% CI −28.1 to 6.1; 