Acknowledgements
We thank Professor R.J. Heald for his guidance and generous help during the study. We thank Hao Chen (Nanfang Hospital of Southern Medical University, China) for the consultation. We thank Dr. Yang Shuo and Dr. Luo Hao (Department of Epidemiology and Biostatistics, School of Public Health; Sun Yat-Sen University), Xiaohua Li (the Third Affiliated Hospital of Sun Yat-sen University, China) for the statistical consultation. This study was supported by grants from the Sun Yat-Sen University Clinical Medicine Research 5010 Program (No. 2015016), the National Natural Science Foundation of China (No. 81971378, No. 81901471) and the Natural Science Foundation of Guangdong Province (No. 2021A1515010577, No. 2022A1515012653). The funder of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the report.