Primary End Point
No patient was lost for evaluation of the primary end point. In the intention-to-treat analysis, 47 of 144 patients (32.6%) in the lumbar drain group and 64 of 143 patients (44.8%) in the standard of care group had an unfavorable outcome at 6 months (unadjusted relative risk, 0.73; 95% CI, 0.51-0.98; absolute risk difference, −0.12; 95% CI, 0.23 to 0.01; 