1. Introduction
obesity, T2D, diabetes
OBESITY, DISEASES, CHRONIC METABOLIC DISEASE, TYPE 2 DIABETES, PATHOGENESIS, DIABETES
These authors contributed equally to this work.The role of probiotic supplementation in type 2 diabetes (T2D) treatment is controversial. The present study aimed to assess the effects of a multi-strain probiotic supplement (LactoLevureType 2 diabetes (T2D) is a common, chronic metabolic disease, with an increasing prevalence often linked to rising obesity rates and an aging population [Recent years have witnessed a surge in interest in the gut microbiome—the astonishingly vast and diverse community of bacteria, fungi, and viruses residing in and on the intestines—as a contributing factor in the pathogenesis of various diseases [Probiotics, defined as living microorganisms with health benefits to humans when administered in adequate amounts [Therefore, the aim of the present study was to conduct a randomized, double-blind, placebo-controlled trial over a sufficient duration (six months) to evaluate the impact of probiotic supplementation primarily on glycemic control (HbA1c), as well as lipid levels, obesity parameters, and associated changes in the gut microbiome in individuals with type 2 diabetes in Greece.