Limitations
This trial has several limitations. As stated above this is a pilot study, a small‐scale study conducted in preparation for a larger investigation. The purpose of the investigators was to increase the likelihood of a successful future randomized clinical trial by exploring the efficiency, internal validity, and fundamentally, the delivery of proposed trial with a small sample size. Nevertheless, the approach by the investigators has been as rigorous and with the same level of scrutiny as a pivotal trial, including public registration and full ethical concerns. Pilot studies are defined as such owing to the uncertainty about the generalizability of the results they report. Thus, although a larger sample size would be ideal our sample size was sufficient given our power analysis. Second, virological assessments after resolution of symptoms were not performed, but the clinical characteristics that were measured indirectly reflected viral activity and were of interest during the pandemic. Third, asymptomatic cases were underestimated because all the follow‐up was based on clinical data.