Principal Findings
comorbidity, Social skill impairment, ADHD
In this randomized controlled trial, we compared the effects of VR-CBT plus LSP intervention with LSP-only treatment in preschool children with ASD. The dropout rate in the intervention group in our study was lower than that reported in previous wearable digital intervention studies (18% vs 33%, respectively) [Social skill impairment is one of the core symptoms of children with ASD. As a result, these children also have obvious obstacles in establishing intimate relationships with others and maintaining eye contact [Most ASD-related intervention studies typically use parent-rated or clinician-rated symptom measures (ie, psychological scales) to evaluate the effect of the intervention, which is subjective. Given that a go/no-go task is a feasible psychological experiment to identify the behavior of children with ASD [The VR-CBT intervention also works more efficiently than single treatment regimens in children with both ASD and ADHD. ADHD is the most common comorbidity in children with ASD, occurring in 25%-81% of this patient population [We noted that the results of the girls differed from those of the boys. A strong male bias in ASD prevalence has been observed in many studies [A previous study has illustrated the critical importance of early detection and treatment for the prognosis of ASD [