DISCUSSION
MCI
This study is the first to implement rEAP in patients with MCI and confirm the effect of rEAP on functional brain networks in patients with MCI using resting-state fMRI. We initially observed that the rEAP group positively affected cognitive function. Furthermore, the increase in ReHo values in the brain regions related to the executive control network in the rEAP group is related to improving cognitive function. Therefore, it implies that rEAP can effectively improve cognitive function in patients with MCI; moreover, it can maintain cognition by improving the patterns of brain activity in patients with MCI. Additionally, this study demonstrated the feasibility of using internet technology to conduct proactive e-health interventions in patients with MCI.