Comparison of ovarian stimulation parameters and ART outcomes
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Comparing ovarian stimulation parameters and ART outcomes, the number of oocytes retrieved (14.60 ± 7.79 vs. 9.84 ± 6.44; P = 0.043), the number of MII oocytes (10.48 ± 6.665 vs. 6.72 ± 4.3; P = 0.041), and high-quality embryos (4.52 ± 2.41 vs. 2.72 ± 2.40; P = 0.024) improved significantly after AST therapy. The number of transferred embryos was similar in the two groups (2.24 ± 0.43 vs. 2.04 ± 0.73; P = 0.203). The fertilization rate (P = 0.382) and multiple pregnancy rate (P = 0.741) were also similar (ART outcomes between AST and placebo groups.AST, Astaxanthin group; Oocyte maturity rate, number of MII oocytes/ number of oocytes retrieved × 100; Fertilization rate, number of fertilized oocytes/ numbers of injected MII oocytes × 100; high-quality embryos, grade A/B cleavage embryos; Fertilization rate, number of injected oocytes with 2 pronuclei (2 PN) and 2 polar bodies (2 PBs) 16-18 h post-insemination/ number of MII oocytes injected ×100. Data are presented as mean ± SD. A P-value less than 0.05 is considered significant (*P < 0.05).