Acknowledgements
This trial is registered as ISRCTN18242823. We thank all the trial participants. We thank Actegy Ltd for providing the NMES devices for the study. We also thank the members of the trial management group, trial steering committee, and independent data monitoring committee for their ongoing advice and support for the trial, and the principal investigators and their colleagues for recruiting and monitoring trial participants and for their hard work and commitment (A complete list of NESIC Trial Investigators is provided in the 