Randomization technique, grouping, and allocation concealment
carious primary molars, caries
CARIES
Fifty children were randomly assigned to two groups according to the caries removal method. Each group comprised 25 carious primary molars; Group I(test group), caries removal by Carie-Care™ chemo-mechanical agent, and Group II(control group), caries removal by the ART method. Randomization was done by the permuted block randomization technique, and the allocation sequence was generated using random allocation software where participants were allotted in blocks of 4. The allocation sequence was then sealed in opaque envelopes by a trial-independent individual who was responsible for keeping the envelopes and unfolding them only at the time of treatment. Blinding of the operator and participants could not be performed because of the difference between the two techniques, but the statistician was blinded to the type of treatment [