Study population
TMJ-OA, malignant disease
TEMPOROMANDIBULAR DISORDERS, SYSTEMIC DISEASE, NEUROLOGICAL DISEASE, TMJ, MAY, MALIGNANT DISEASE
This randomized, single- blinded, prospective study was conducted with patients who were seen at the maxillofacial surgery clinic of the Faculty of Dentistry of Adıyaman University between May 2019 and November 2021. The included patients were diagnosed with TMJ-OA through clinical and radiological examinations based on the Diagnostic Criteria for Temporomandibular Disorders (axis I group I b). The study protocol was approved by the Turkey Republic Adıyaman University Clinical Research Ethics Committee on 22/01/2019 (approval number 2019/1–2), and all patients signed an informed consent form. The study was conducted in full accordance with the Declaration of Helsinki.The study was planned with 38 patients, but 8 patients were excluded because they did not attend follow-up visits. The inclusion criteria were patients who were diagnosed with TMJ-OA clinically and radiologically, 18 years of age and older, and sufficient clinical data at baseline and follow-up. Patients were excluded from the study if they had uncontrolled systemic disease, neurological disease, previous TMJ surgery, malignant disease in the head and neck region, or did not come to follow-up visits. The appropriate sample size was computed with a significance level of 0.05 and power of 80% to detect a clinically meaningful difference of 4 mm in the interincisal opening. The power analysis indicated that 11 patients were needed in each group.