Primary angioplasty and non-culprit PCI
ischemia, Ischemia
ISCHEMIA, STENOSIS, ISCHEMIA
Patients underwent primary PCI with placement of stents as per local hospital practices. Patients randomized to the routine non-culprit PCI arm underwent PCI of the angiographically significant lesions (≥ 70% diameter stenosis) in non-culprit vessels either immediately (during the index primary PCI), or as a staged procedure preferably within 6 weeks after the index PCI. Patients in the ischemia guided arm underwent PCI to non-culprit vessels if the stress MPI showed at least mild inducible ischemia as determined by an SDS ≥ 4. Ischemia testing was not required if patients were symptomatic. Investigators were encouraged to perform the PCI as early as possible after randomisation. The choice of stents, antiplatelet agents and adjunctive therapies were left to the discretion of the treating cardiologist, in keeping with international guidelines and local practices.