Supplemental lactoferrin has a limited impact on gut microbial and metabolite composition
The impact of supplemental lactoferrin versus placebo was assessed using mixed-effects models incorporating available clinical variables. No significant difference was observed in bacterial Shannon diversity between infants receiving lactoferrin (mean 1.24) or placebo (mean 1.06) at 34 weeks corrected age (p=0.11) or across all timepoints (p=0.53) (corrected alpha diversity comparisons per individual analysis mode (table), 