Statistical analyses
Categorical variables were described as counts and percentages, and continuous variables were described as medians and ranges. Comparisons of categorical variables were performed by Fisher's exact test, and continuous variables were compared by the Mann–Whitney's U test. The Wilcoxon signed rank test was used for defining significant changes in QoL before versus after therapy. PFS was calculated by the Kaplan–Meier test for univariate analyses. The value of α was 0.05, two‐tailed, and 