Safety analysis and comparison of respiratory adverse events in two groups of patients within 4 weeks after treatment
pneumonia, chest tightness, expectoration, wheezing, atelectasis, pain, cough, hypoxemia, bronchial stenosis, hypercapnia, phlegm, COPD
ADVERSE REACTIONS, PNEUMONIA, ADVERSE EVENTS, ATELECTASIS, COPD
In the combined BT treatment group, the main adverse events in patients with COPD within 3 weeks after treatment were cough, phlegm, and short-lived wheezing. Specifically, there were cough (39 cases), increased expectoration (32 cases), short-term wheezing (32 cases), blood in sputum (8 cases), chest tightness and pain (4 cases), pneumonia (3 cases) cases), focal atelectasis (13 cases), hypoxemia (1 case), and hypercapnia (2 cases). Most adverse events resolved spontaneously 1 week after operation or disappeared after symptomatic treatment, such as sputum suction under bronchoscopy and non-invasive ventilator-assisted ventilation. In addition, no structural changes such as bronchial stenosis or tracheal dilatation or segmental atelectasis occurred during postoperative chest computed tomography (CT) follow-up. There were no patients in each group who terminated the study early due to adverse reactions or experienced serious adverse reactions within 3 weeks.