Secondary endpoints
PD, deaths, SD, TTP
DISEASE, DISEASE PROGRESSION, SECONDARY, TTP
The results of the analyses conducted to assess the secondary endpoints are comprised in Table Secondary endpoints.ORR, overall response rate. CR, complete response. PR, partial response. SD, stable disease. PD, progressive disease. DOR, duration of response. TTP, time to progression. OS, overall survival. FAS, full analysis set.*Equivalent to PFS as all deaths were considered as cancer-related.°41 patients have died at time of the current analysis.Assessment of the ORR showed no complete response (CR). 7/48 patients achieved a partial response (15%), and the majority of patients either had stable disease (SD) or disease progression (PD), regardless of EGFR expression status. Similarly, median OS did not differ between the FAS, the EGFR+ and EGFR++/+++ subgroup.