Clinical outcomes
infection, renal graft dysfunction
COMPLICATION, INFECTION, VENOUS THROMBOSIS, RENAL DISEASE, COMPLICATIONS
The primary outcome measure was DGF, defined as the requirement for dialysis in the first week after transplantation. Secondary outcome measures included incidence of PNF; duration of DGF; functional DGF defined as less than 10% fall in serum creatinine for three consecutive days in the first week after transplantation; CRR2 (creatinine day 1 − creatinine day 2 / creatinine day 1 × 100), CRR5 (creatinine day 1 − creatinine day 5 / creatinine day 1 × 100); duration of hospital stay; serum creatinine and eGFR at 1, 3, 6 and 12 months using the Modification of Diet in Renal Disease (MDRD) 4 variable equation; and patient and allograft survival up to 12 months after transplant. For safety outcomes, the total number of incidences of biopsy-proven acute rejection, renal artery or venous thrombosis, complications of the renal transplant biopsy and the number of hospital admissions for any recognized complication of the renal transplant, including renal graft dysfunction, infection, surgery related or due to the immunosuppression, were recorded.Data were collected by each of the participating transplant centers using an online secure database hosted by the NHSBT Clinical Trials Unit.