Randomisation and masking
Patients were randomized in a 1:1 ratio to erenumab or placebo using randomization and medication lists created by the Contract Research Organization’s statistician through a validated SAS program. Randomization was stratified by center. Patients, investigators and the clinical trial team remained blinded to treatment allocation. Erenumab and placebo were supplied in two 70 mg/1 mL pre-filled syringes. Treatments were identical in packaging, labeling and appearance.