Outcomes
REGIONE LOMBARDIA - Research, TG
TUMOUR NECROSIS, SECONDARY
The present double-blind, randomized and placebo-controlled pilot study is part of the largest Food social sensor Network (FoodNET) project, funded by REGIONE LOMBARDIA - Research and Innovation, co-funded by POR FESR 2014–2020 (CUP E47F17000020009), and previously described elsewhere (The study aimed at investigating in free-living older adult volunteers (aged ≥ 65 years) the effect of a functional food (e.g. crackers) prepared with Camelina sativa oil and consumed as a snack on:
serum polyunsaturated fatty acid profile (by measuring ALA: α-linolenic acid; EPA: eicosapentaenoic acid; DHA: docosahexaenoic acid; LA: linoleic acid; ARA: arachidonic acid levels) (primary outcome);inflammatory status parameters, paying particular attention to pro-inflammatory cytokines (by measuring IL-18: interleukin - 18; TNF-alpha: tumour necrosis factor-alpha levels); anti-inflammatory cytokines (by measuring TGF- beta 1: transforming growth factor-beta 1; TGF-beta 2: transforming growth factor-beta 2 levels) and C-Reactive Protein (CRP) levels (secondary outcome);serum lipid panel parameters (by measuring total cholesterol, TC; high-density lipoproteins cholesterol, HDL; low-density lipoproteins cholesterol, LDL; triglycerides, TG; concentrations) (secondary outcome).