Discussion
VF, strabismus, nystagmus, glaucoma, TEMPO
DISEASE, STRABISMUS, NYSTAGMUS, DYSFUNCTION, GLAUCOMA, ANISOMETROPIA
In this study, we prospectively performed VF testing with both TEMPO AIZE-Rapid and HFA Swedish Interactive Threshold Algorithm (SITA)-Fast in a randomized order and identified a stronger structure–function relationship and better reliability indices with TEMPO compared to HFA. TEMPO reduced measurement time by approximately 40% without compromising perimetric performance. Even though the participants were inexperienced with TEMPO prior to the study, it was strongly preferred by patients.Effective glaucoma management necessitates functional and structural exams, and correlating these changes ensures reliable tracking of disease progressionThe average differences in MD, PSD, and VFI between TEMPO and HFA were all within 1 dB. While the mean difference between the measurements was minimal, we observed a trend where the difference increased with the severity of glaucoma (see Supplemental Fig. HFA SITA-Fast and TEMPO AIZE-Rapid have several items in common regarding reliability indices, but there are some differences. First, false positives are calculated by both devices using reaction time. HFA SITA-Fast uses the percentage of stimuli responded to within a minimum reaction time with an adjustment for the average reaction time of the individual patientThis study has several limitations. First, it was based on participants from a tertiary care academic practice, which could introduce certain biases in socio-economic status, demographics, and severity of disease, which could differ from those of patients treated in other settings. This could potentially restrict the generalizability of our findings. Second, the current software is derived from a database that only consists of data from the Japanese population. Regardless of this limitation, HFA and TEMPO exhibited excellent agreement. Third, certain situations, such as conditions of binocular vision dysfunction like strabismus, anisometropia, nystagmus among others, can render binocular open-eye examinations unfeasibleIn conclusion, TEMPO showed a stronger structure–function relationship with Cirrus OCT. Further studies are necessary to evaluate the potential of this binocular VF test for longitudinal monitoring.