Subject inclusion and exclusion criteria
organic diseases of the eye, congenital cataract, strabismus, optic nerve dysplasia, corneal astigmatism, myopia, disturbance of consciousness, diabetes
SYSTEMIC DISEASE, STRABISMUS, CORNEA, MYOPIA, CHROMOSOMAL ABNORMALITIES, CYCLOPLEGIA, INTRAOCULAR PRESSURE, DIABETES
Inclusion criteria: (1) diopter -5.0 D to -1.00 D (cycloplegia), conforming corneal astigmatism less than 1.50 D, Inverse corneal astigmatism less than 0.75 D; (2) corneal topography, the minimum curvature of the cornea (D) minus the expected reduction greater than 36 D, (3) corneal diameter of 10.9 - 12.5 mm, best-corrected visual acuity (BCVA) > 0.0 logMAR; (4) myopia children, 8 - 12 years old, willing to participate in 13-month observation.Exclusion criteria: (1) with organic diseases of the eye, such as strabismus, congenital cataract and optic nerve dysplasia; (2) with a history of ocular surgery; (3) suffering from visual functional systemic diseases such as diabetes and chromosomal abnormalities; (4) with previous use of contact lenses, bifocal or multifocal lenses, or other myopia treatments (such as atropine eye drops); (5) patients with intraocular pressure higher than 21 mmHg; (6) unable to understand the mechanism of action of Orth-K and potential problems and limitations of patients with correction; (7) patients with disturbance of consciousness or unconsciousness.