5. Conclusions
breast cancer
BREAST CANCER
We demonstrate a plausible causal association between soy isoflavone intake and mammographic density change, as a biomarker of breast cancer risk, among Asian women around or soon after menopause. However, due to the limited sample size in this trial, the findings should be interpreted with caution and require confirmation in a larger trial of Asian women that appropriately accounts for the habitual intake of soy isoflavones in this population. Nonetheless, it suggests that a diet rich in soy isoflavones could be an important, cost-effective, and acceptable primary prevention strategy for breast cancer risk in a region that is currently observing alarming increases in breast cancer incidence.