Author contribution
KHK, BTG, AMØ, HR, and CB designed the trial. AH, LARR, BA, KF, CB, and SIH included patients and performed all trial visits and clinical data collection. DB developed and taught the clinical staff the cryoablative procedures. KHK, AMØ, KF, JRO, and WA performed the sample preparation and laboratory analyses. SHK, GKM, IB, and GK performed the leukapheresis and production of autologous immature dendritic cells. EKK performed the flow cytometry analyses. LARR, AH, TMH, and MB. analyzed the radiologic images. AB, OJH and LAA performed the histological review, the immunohistochemical staining and evaluations, and related statistics including survival analyses. SK performed the genetic assay analyses. KP and SR performed the CTC analyses. KHK, CB, AB, BG, SK, AH, LARR, and LCVT analyzed the data. LCVT, AH, BTG, KHK, AH, and CB wrote the manuscript. All authors read and approved the final manuscript.