Authors’ contributions
QQ and YW designed the study. SX, TZ, and XL performed the clinical trials. JG, XH, QS, and DL assisted in the completion of the clinical trials. WOY, YZ, CD, and WZ conducted data collection. JG and DP analyzed the data. DP wrote and edited the manuscript as well as composed the figures. SX and YW proposed amendments to the manuscript. All authors approved the final version of the manuscript.