Consent
Each participating center obtained ethics approval through their local Research Ethics Committee. This study’s protocol has been registered with the Comité d’Ethique pour les Recherches (CER) of Toulouse University under the number: 2018–099 for the centers in Toulouse and Clermont-Ferrand (France) and by the Health and Research Authority in Wales (Ref 19/HRA/5142) for the centers in Oxford and Coventry (United Kingdom). All participants gave written informed consent.