PD of TQA3526
The mean changes in ALP and cholesterol levels were not significant after a single dose of TQA3526 (1–10 mg). The bile acid decrease (Pharmacokinetic/pharmacodynamic profiles of FGF-19 for the single ascending dose study.The mean ALP, bile acid, and cholesterol level changes were not significant after a single dose of 10 mg TQA3526 in the fasted and fed states (Mean (±The mean ALP level gradually increased after multiple doses of 2 mg QD until the end of the study (Mean (±