4.1.2. Study Participants
cancers, allergy
HYPERSENSITIVITY REACTIONS, CANCERS, ALLERGY, DISORDERS, SKIN DISEASES
This study was performed from April 2022 to June 2022. Healthy adult women, aged 19–69 years, were eligible for this study. The main exclusion criteria were as follows: major internal disorders, such as cancers, major or active skin diseases, current pregnancy or lactation, history of allergy or hypersensitivity reactions, history of undergoing dermatologic procedures (e.g., lasers, filler, botulinum toxin injection) in the past 3 months, use of topical medications with any skin reactions (e.g., glucocorticoids, retinoids, and topical immunomodulators) in the past 3 months, use of systemic medications, such as glucocorticoids and immunomodulators within the last 1 month, and application of skin care products or topical medications with similar functions in anti-aging within the last 3 months before participating in the study.