Background
Muscle perturbations, exertional leg symptoms, claudication, peripheral artery disease
PERIPHERAL ARTERY DISEASE
Supervised exercise programs are effective rehabilitation for patients with peripheral artery disease (PAD)-related claudication, delivering improvement in exercise performance, quality of life (QoL), and exertional leg symptoms.Low-intensity resistance exercise with blood flow restriction (BFR) is becoming popular as a rehabilitation tool for clinical populations that are intolerant to high-intensity protocols.Muscle perturbations and hemodynamic disruption facilitated by the cuff are thought to activate systemic hormone production,BFR represents an alternative exercise method for aiding rehabilitation and has potential utility in patients with claudication. Although BFR protocols appear safe and acceptable to a variety of populations,