Results
femoral venous sheath, hypoxia, vasovagal
HYPOXIA, ADVERSE EVENT
Thirty subjects were included between November 2020 and June 2021. Data from two subjects were excluded from the analysis due to technical issues with the gas mixing system (n = 1) and blood sampling (n = 1). One subject was excluded being an outlier in terms of body mass index (> 3 SD above the mean value). One subject did not start the hypoxia procedure due to an adverse event (vasovagal response) during femoral venous sheath placement. In three subjects the hypoxia procedure was prematurely terminated due to a decrease in mean arterial pressure of more than 30% of the baseline value after the 90% (n = 1) and 75% (n = 2) SpO
Overview of hypoxia sequence. The radial artery (black dots), renal vein (grey dots) and iliac vein (white dots) oxygen saturations are represented as mean (standard deviation). The lines connecting the points are purely representative
Trends of O3-derived oxygen saturation values measured at the quadriceps (blue line) and at the flank (red line), and of somatic reference saturation values (boxplots) along the hypoxia procedure. The red and blue lines and shaded areas represent the median and interquartile range (IQR) of O3-derived oxygen saturation values. The boxplots represent the median and IQR of somatic reference, the vertical whiskers correspond to 1.5 IQR, and the horizontal whiskers represent the SpO
Physiological variables, blood gas values, O3-derived oxygen saturation values and reference saturation values along the hypoxia procedure* p < 0.001 vs. baseline; † p < 0.05 vs. baseline; ‡ flank sensor side: same as femoral venous sheath; § flank sensor side: same as renal vein catheter. 