Patients
cancers, death, cirrhosis, tuberculosis, neuromuscular disease, consumptive diseases, HCC, malnutrition
CANCERS, LIVER, CIRRHOSIS, TUBERCULOSIS, NEUROMUSCULAR DISEASE, HYPERTHYROIDISM, HEPATOCELLULAR CARCINOMA, MALNUTRITION
Patients with HBV-ACLF who were admitted at the First Affiliated Hospital of Chongqing Medical University between January 2012 and August 2021 were included in this study retrospectively. The following were the inclusion requirements: (1) 18 years and over; (2) hepatitis B surface antigen (HBsAg) and/or HBV DNA positive for more than 6 months; (3) ACLF is diagnosed using the Asia–Pacific Association for the Study of the Liver (APASL) criteriaPatients who fit any of the following descriptions were ineligible: (1) ACLF combined with cirrhosis; (2) diagnosis of hepatocellular carcinoma (HCC) or other cancers; (3) concurrent consumptive diseases such as tuberculosis or hyperthyroidism; (4) undergoing prolonged corticosteroid treatment; (5) malnutrition due to neuromuscular disease or prolonged bedridden state; (6) death or receiving a liver transplant; and (7) significant weight changes in the short term.The Ethics Committee of the First Affiliated Hospital of Chongqing Medical University approved this observational retrospective cohort study (2022-K434) with a waiver of patients' informed consent. The study was carried out in accordance with the Declaration of Helsinki.