Introduction
non-inflammatory degenerative disease, KOA, synovial joints, Knee osteoarthritis, trauma
KNEE OSTEOARTHRITIS
Knee osteoarthritis (KOA) is a multifactorial, slow-progressing, non-inflammatory degenerative disease primarily affecting synovial joints. It is usually induced by advanced age and/or trauma and eventually leads to irreversible destruction of articular cartilage and other tissues of the joint [