Sparse Partial Least Squares Discriminant analysis of patient randomised to ketogenic feeding on Day 10 (red triangle) and control feeding on day 10 (blue sphere).
Clockwise from top right: Each arm additionally demonstrated changes (VIP scores>1) in metabolite abundance over time. In the control arm, 37 non-polar negative, 39 non-polar positive, 41 polar negative and 18 polar positive metabolite abundances were differentially altered over time (Fig. 