WHAT IS ALREADY KNOWN IN THIS TOPIC
DISEASES
Vaccine hesitancy can have serious public health consequences, as it can lead to outbreaks of vaccine-preventable diseases, particularly in countries with low vaccination rates.Concerns about the safety and effectiveness of vaccinations, including misinformation, mistrust of healthcare workers or pharmaceutical companies, religious or philosophical convictions and fear of side effects are all potential causes of vaccine hesitancy.While human-centred design (HCD) has proven beneficial in several health campaigns, evidence regarding whether, how or to what effect HCD can be used to bolster vaccination confidence in low and middle-income countries is lacking.