Treatment outcome and lesion evolution
hemorrhagic
In our population, ninety (87%) of the patients achieved successful recanalization (eTICI ≥ 2b). Lesion and non-hemorrhagic volumes after 24 hours and 1 week were significantly lower in patients that achieved successful recanalization. Lesion and non-hemorrhagic growth were comparable in patients with and without successful recanalization. Details of these comparisons are provided in The treatment success rates were similar in patients receiving IVT before EVT and patients that underwent direct EVT (47(84%) vs. 43 (90%), p = 0.58). All lesion, non-hemorrhagic and hemorrhagic characteristics were comparable between patients that did and do not achieve successful recanalization in the direct EVT treatment arm. However, the 1-week lesion and non-hemorrhagic volume were significantly larger in patients that did not achieve reperfusion in the IVT before EVT treatment arm (p = 0.04, p = 0.03). Details of these comparisons are provided in the Supplementary Table 3.