Unadjusted and Multivariable Adjusted Tobit Regression
Depression, Anxiety
People who stopped smoking had a lower HADS score at week 24 than those who continued smoking. Anxiety was lower by −0.28 point (95% CI, −0.41 −0.14 point) unadjusted and −0.40 point (95% CI, −0.58 to −0.22 point) adjusted. Depression was lower by −0.29 point (95% CI, −0.40 to −0.19 point) unadjusted and −0.47 point (95% CI, −0.61 to −0.33 point) adjusted. There was no evidence of a difference between people who were randomized to active drugs vs those randomized to placebo in mental health outcomes (eTable 1 and eTable 2 in 