Safety of intervention
nausea
A questionnaire was used to record the possible severity of adverse symptoms in pregnant women and the relationship between symptoms and the ingestion of preparations. The results showed that one participant in GOS group had abdominal distension and one participant had nausea. These symptoms have little to do with the intake of prebiotic preparations, and may be related to appetite and hormone changes during pregnancy. Therefore, for the existing included cases, it can be considered that supplementing prebiotic preparations during pregnancy is relatively safe.