Statistical analysis
PD, SD
DISEASE
SPSS 22.0 (IBM, Armonk, NY, USA) was used for statistical analysis. Continuous data were tested with the Kolmogorov–Smirnov test for normal distribution. Normally distributed continuous data are expressed as means ± standard deviations, and non‐normally distributed continuous data are expressed as median (ranges). Partial response (PR), stable disease (SD), progression of disease (PD), objective response rate (ORR), disease control rate (DCR), overall survival (OS), and PFS were calculated by using the exact binomial distribution. OS and PFS were estimated by using the Kaplan–Meier method. Only descriptive statistics were used and none of the statistical tests were applied.