Authors’ contributions {31b}
JP, AD
BW conceived the study, led the proposal and protocol development. LZ is the principal investigator, led the proposal and protocol development. JP contributed to study design and was in lead of the power and statistical analyses. JV contributed to the development of the proposal and is in lead of the independent breast surgeon panel. JW contributed to the study design and to development of the proposal. LS is the senior investigator, conceived the study, contributed to the study design and to development of the proposal. RE, HW, AO, AD, YR, SV, ASV, MHG participate in the study as local investigators. All authors read and approved the final manuscript.