Association between the nutritional biomarker score of the Mediterranean diet and incidence of T2D in the EPIC-InterAct case-cohort study (
REGRESSION
The biomarker score was derived as a discriminatory model between the Mediterranean and habitual diet in the MedLey randomised partial-feeding controlled trial. Circulating carotenoids and fatty acids were used to calculate the score as linear predictions from the discriminatory model. Associations were assessed with the Prentice-weighted Cox regression and pooled by random-effects meta-analysis. Top: The diamond and error bars of the pooled estimate represent the 95% confidence and prediction intervals. Bottom: Restricted cubic splines with 5 knots were used to model the nonlinear association. The 