Caregiver’s perception
REGRESSION
To assess the perception of the caregivers, throughout the study they were asked to evaluate how disturbing they considered the scratching over the last seven days using a visual analogue scale (see A) Change of the perceived disturbance due to scratching during the previous 7 days. B) Overall evaluation of the scratching problem over the last 28 days using Xi 2 test. * represents significant difference of at least p<0.05 and *** for p<0.001.Only 10.6% in the Pheromone group did not report any change either in Frequency or Intensity compared to 27.4% in the Placebo Group (p<0.001) (See A good correlation between the Disturbing value and the Global Index Score was found (R squared = 47% and p<0.001 with simple linear regression), however a large variability around the linear regression was observed (see 