Introduction
hip joints, Osteoarthritis, OA, Pain, crepitation, stiffness, weight loss
AIDS, OSTEOARTHRITIS, JOINT DISORDER
Osteoarthritis (OA), which is considered one of the leading causes of disability, is a chronic, progressive, and the most common form of joint disorder. Pain, crepitation, stiffness, and decreased range of motion in involved joints, especially knee and hip joints, were reported as OA results [As we know, there is a vast range of treatment approaches related to OA management, such as non-pharmacological and pharmacological approaches. Non-pharmacological approaches include weight loss, the use of ambulatory aids, exercise, muscle strengthening, and physiotherapy. In contrast, pharmacological treatments include simple analgesics and nonsteroidal anti-inflammatory drugs (NSAIDS). If such treatments would not be effective, therefore, intra-articular knee injections may be considered one of the most efficient non-surgical approaches [Intra-articular injection of platelet-rich plasma (PRP), intra-articular injection of plasma rich in growth factors (PRGF), intra-articular injection of hyaluronic acid (HA), and intra-articular injection of ozone are defined as Intra-articular knee injections [One of the well-established non-surgical treatment options which have received significant attention from clinicians is Intra-articular injections, which several studies demonstrated their effectiveness. Regarding this, there are number studies that investigate the cost-effectiveness of intra-articular injections. Some of these studies compared two intra-articular injectable options such as PRP and HA [