Statistical analysis
death
DEL
The primary endpoint of this study was progression‐free survival (PFS, measured from the date of diagnosis to confirmed relapse or death from any cause). Secondary endpoints were overall survival (OS, measured from the date of diagnosis to death from any cause), response rate and relapse rate.To determine differences in categorical variables (sex, age, DEL status, etc.) from independent samples, Cox proportional hazards model was used to estimate the effects of the prognostic risk factors by univariate and multivariate settings with loss‐to‐follow‐up point censoring. Proportional hazards assumption was verified for all models. Only factors with The sample size of the study protocol was estimated to test the difference in 3‐year PFS and relapse incidence between selected groups. The closest in design and inclusion criteria RCT with ours reported 13% relapse rate after upfront HDCT with auto‐HSCT.A two‐sided 