Ethical approval
WEST
for this trial was received from the Ethics Committee of West China Hospital of Sichuan University (No. HXDZ21006). The first participant was enrolled on December 1, 2022. We expect to finalize the study by November 30, 2026. Protocol version 1.0 document completed in December 2022. Any modification to the protocol that may affect the conduct of the study, the potential benefit to patients, or patient safety must be approved by the Ethics Committee before implementation.