4. Discussion
inflammation
INFLAMMATION
In the present study, we determined the effect of five days of AA supplementation on iron regulation after a single session of endurance exercise. The main finding was that five days of AA supplementation did not attenuate the exercise-induced increase in hepcidin. However, AA supplementation was associated with augmented IL-6 and glycerol levels post-exercise.Serum hepcidin levels increased significantly 3 h after endurance exercise in both trials. This result is consistent with previous studies that have reported transient increases in the serum hepcidin level 3–6 h after acute endurance exercise [Exercise-induced IL-6 has been associated with increases in serum hepcidin levels post-exercise [In the present study, IL-6 was the only inflammatory marker [As well as having an inflammatory effect, IL-6 is a myokine secreted from working muscles in response to an energy deficit and plays a role in promoting catabolism through lipolysis [There were potentially confounding factors associated with the outcomes of the present study. Sleep deprivation augmented markers of inflammation [The present study had some limitations that should be discussed. First, we used maltodextrin as a PLA supplement. Several studies have shown that carbohydrate intake affects IL-6 production [