4.2. Procedures 
shock, cardiovascular diseases
HEAT, CARDIOVASCULAR DISEASES, SHOCK, DIABETES MELLITUS, CARBOHYDRATE METABOLISM DISORDER, CHRONIC INFLAMMATION, DISEASES
Before IHHE or sham treatment, all patients underwent a routine medical examination, with a collection of medical history, data on the intake of drugs, family history for cardiovascular diseases, carbohydrate metabolism disorders, diabetes mellitus, and other diseases. One day before the experimental sessions, and 2–3 days after the last training, the patients of both groups underwent the same examinations and measurements: an evaluation of hemodynamic parameters (blood pressure (SBP and DBP) at rest, heart rate (HR)), SpOTMAO was measured in plasma and fecal samples, as described below. In addition, blood samples were collected to determine serum lipid levels (TCh, HDL, LDL, Mmol/L); liver enzymes—alanine aminotransferase (ALT, units per liter) and aspartate aminotransferase (AST, units per liter); markers of chronic inflammation—CRP-hs (mg/L), heat shock proteins-70 (HSP70, ng/mL); and N-terminal prohormone of brain natriuretic peptide (NTpro-BNP, pmol/L), and were reported in our previous study [