Background
Gastric cancer, colorectal cancer, Neo-CRAG, HT, deaths
GASTRIC CANCER, CERVICAL CANCER, COLORECTAL CANCER
Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide, with > 40% of new cases being detected in China [Previous studies have reported the relationship between HT and bone marrow radiotherapy dosimetry, though the majority of them were about pelvic bone irradiation in cervical cancer and colorectal cancer [The Neo-CRAG trial (NCT 01815853) [In the preliminary data analysis, we noted a trend of increased HT in the nCRT group than in the nCT group, as well as an association between vertebral body (VB) dosimetry and HT grade. Thus, identifying the dosimetric parameters associated with HT could be critical for bone marrow-sparing in radiotherapy planning. Therefore, this study aimed to explore the difference in the risk of HT between nCRT and nCT groups and to identify the best predictive dosimetric factors of HT for locally advanced GC.