2.4.4. Clinical Global Impressions (CGI) Scale
ill
ADVERSE EVENTS
This brief, 3-item assessment tool provides a global rating of illness severity (CGI-S), global improvement or change (CGI-I), and therapeutic efficacy (CGI-E). CGI-S is measured on a 7-point scale ranging from 1 (normal, not at all ill) to 7 (among the most extremely ill patients). CGI-I is measured on a 7-point scale as well, ranging from 1 (very much improved) to 7 (very much worse). CGI-E takes into account both the therapeutic effect and adverse events, ranging from 1 (marked therapeutic effect) to 04 (unchanged or worse). Our study utilizes a CGI-E final index score ranging from 0–16 which depends on separate subscale ratings of therapeutic benefits versus side effects.