4.2. Conclusions
inflammation
INFLAMMATION, EVENTS, DISEASES
Demonstrating the direct effects of vitamin D supplementation on ultramarathon-induced changes in serum amino acid levels can prove that effective vitamin D supplementation (which is associated with an increased blood concentration of vitamin D metabolites) could suppress protein degradation. Some evidence for the presented activity of vitamin D in muscle protein turnover was already known almost forty years ago, for example, in Wassner et al.’s work [Over the years, many researchers have proven that vitamin D supplementation can inhibit muscle protein degradation caused by external factors, ageing, diseases, or, essentially, demanding exercises [However, considering the multi-directional activity of vitamin D (from the inhibition of inflammation to metabolic regulation, body homeostasis, mitochondrial activation, and hormonal regulation), its appropriate status in sports competition seems to be very beneficial or even essential to maintaining good health. This study provides substantial value for understanding physiological responses to extreme endurance events with respect to these compounds and their role in extreme physical exertion.