Measurement
Liver stiffness, fatigue
HEPATITIS B, VIRUS
We assessed fatigue using the FSS-9, including items considering mental and physical functioning, motivation, carrying out duties, and interfering with work, family, or social life. The FSS-9 is a well-known questionnaire to quantify fatigue during the week prior to the assessment [We drew blood samples, including hepatitis B virus surface antigen, HIV antigen/antibodies, thrombocytes, and aspartate aminotransferase, as well as HCV antibodies and HCV polymerase chain reactions. Liver stiffness was measured by calculating the aspartate aminotransferase to platelet ratio index and performing transient elastography at baseline (Additional file 