Statistical analysis
HAE
REGRESSION
Standard descriptive statistics were used for all presented data. Group differences were analyzed with Fisher’s exact test for categorical variables, and Mann-Whitney U test for continuous and ordinal variables as normal distribution could not be assumed.Survival analysis was performed using Cox regression to analyze the impact of HAE and a delay of chemotherapy courses by 2–6 weeks. Given the time-dependent nature of HAE and delayed chemotherapy courses, i.e. an increasing cumulative incidence in patients receiving longer treatment, a landmark analysis was performed [Uni- and multivariable logistic regression was performed to predict HAE during the concomitant phase of chemotherapy using previously published parameters [