Radiological response evaluation and metastasis burden calculation
METASTASIS
Radiological response to combined nivolumab/ipilimumab was assessed in three months intervals after treatment initiation according to RECIST version 1.1 by reference radiologists in the field of CUP. Metastasis burden was defined as a function of the sum of diameters of all target lesions added to the score that resulted according to Supplementary Table 