Statistical analysis
atelectasis
RECRUITMENT, ATELECTASIS
The results of this publication are based on an exploratory analysis of the results of the data from ventilated children.The change in regional ventilation fraction during general anesthesia was examined in an exploratory analysis. The changes were analyzed graphically (see Figs. Ventilation distribution based on horizontal layers—ROI 1–4. The middle horizontal marker illustrates the grouping of ROI 1 and 2 as the ventral layer, and ROI 3 and 4 as the dorsal layer. The dorsal layer is 5.5 percentage points more ventilated at the time of spontaneous breathing (SB) than at the time of controlled ventilation (PCV)Plot of ventilation at the three intervention time points PCV, PSV and SB. ROIs 1 and 2 were combined into ROI ventrally, ROIs 3 and 4 into ROI dorsally. In the dorsal regions, there is an increase in ventilation by recruitment of dorsal atelectasis by a mean of 5.5 percentage points with increasing spontaneous breathing. In turn, the ventilation fraction of the ventral lung regions decreasesA Wilcoxon signed-rank test was used to compare the reduction in EELV and the distribution of EELV during ventilation and spontaneous breathing (see Fig. Plot of EELV changes at the three ventilation mode transitions. Ventral lung areas (left) and dorsal lung areas (right) show how the total ∆EELV change is proportionally distributed between the two regions at the corresponding ventilation mode transitions of ventilation. In addition to the boxplots, the change for each individual patient is plotted. To allow assignment over the course of individual study participants, the values are connected by gray lines. The values of the study population do not show a normal distribution. Due to statistical outliers, the median values are used as measure of location. The dorsal regions show an increase, which can be explained by the recruitment of atelectasis due to the onset of spontaneous breathing. Due to the loss of PEEP after termination of mechanical ventilation, the overdistension in the ventral lung regions decreases and thus the proportion of ∆EELVAll statistical analyses of this study were performed using the program "R" (version 4.2) and a 