Effect of ABL on bone strength indices
Comparisons of bone strength indices (CSMI, SM, and BR) from baseline between the ABL and PBO groups over time are shown in Fig. Mean percent changes from baseline in DXA-based bone strength HSA indices. (Compared with PBO, 78 weeks of ABL injection showed a significant difference in CSMI at the NN (6.7%; 95% CI, 3.83, 9.54) and IT (3.6%; 95% CI, 0.36, 6.91); in SM at the NN (6.1%; 95% CI, 3.34, 8.81), IT (4.5%; 95% CI, 1.56, 7.44), and FS (2.6%; 95% CI, 0.76, 4.46); and in BR at the IT (− 5.9%; 95% CI, − 7.62, − 4.08).