Other outcomes
PD, OI, TNF-α
Compared with group C, the extubation time and length of ICU stay in group PD were decreased (Comparison of postoperative resuscitation among four groupsCompared with group C, OI of groups P, D and PD at T4, T5 and T6 after CPB was higher than that of group C (all Comparison of oxygenation index among four groupsCompared with T0, RI of groups P, D and PD at T4, T5 and T6 after CPB was better than that of group C (Comparison of RI among four groupsCompared with T0, To investigate whether administration of penehyclidine hydrochloride and dexmedetomidine during anesthesia for heart valve surgery reduced the release of serum inflammatory cytokines, we measured serum proinflammatory cytokine levels during and after surgery. Compared with before anesthesia (T0), the serum concentrations of TNF-α and IL-6 in the four groups at T4, T5 and T6 after CPB were significantly increased (Comparison of serum TNF-α, IL-6, CRP and procalcitonin levels among four groups. The parameters depicted are 