Type of participant and disease characteristics
ischemic cardiovascular disease, apneacardiovascular disease
HEART

had a BMI of:≥30 kg/m≥27 kg/mhypertension: treated or with systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mmHgdyslipidemia: treated or with LDL ≥ 160 mg dlobstructive sleep apneacardiovascular disease (for example, ischemic cardiovascular disease, New York Heart Association Functional Classification Class I–III heart failure)had a history of at least one self-reported unsuccessful dietary effort to lose body weightin the investigator’s opinion, were well motivated, capable and willing to:learn how to self-inject study drug, as required for this protocol (visually impaired persons who were not able to perform the injections must have had the assistance of a sighted individual trained to inject the study drug; persons with physical limitations who were not able to perform the injections must have had the assistance of an individual trained to inject the study drug)inject study drug (or receive an injection from a trained individual if visually impaired or with physical limitations)follow study procedures for the duration of the study, including—but not limited to—following lifestyle advice (for example, dietary restrictions, exercise plan), maintaining a study diary and completing required questionnaires