Conclusions:
infection
INFECTION
Even with extensive surveillance screening, almost one-third of all ESBL-E days were nonisolation days. Limitations in routine culture-based ESBL-E detection impeded timely and exhaustive implementation of targeted contact isolation.Many guidelinesBoth the effectiveness and the clinical relevance of ESBL-E screening programs have been questioned.To guide infection control interventions effectively, the turnaround time of the procedures should be as short as possible to avoid delay until the initiation of contact isolation or to avoid unnecessary isolation days in the case of pre-emptive isolation measures for patients at risk of carriage.A large cluster-randomized trial in 20 non-ICU wards from 4 European countries reported no additional benefit of contact isolation over standard precautions to prevent new acquisition of ESBL-E.