Subject terms
glioblastoma, cancer, herpes, tumour
VIRUS, CANCER, HERPES, TUMOUR, GLIOBLASTOMA
Immunotherapy failures can result from the highly suppressive tumour microenvironment that characterizes aggressive forms of cancer such as recurrent glioblastoma (rGBM)Treatment with the oncolytic herpes virus CAN-3110 is associated with improved survival responses in patients with recurrent glioblastoma, particularly in individuals who are seropositive for HSV1.