Data processing and analysis plan
pain
CROSS
Data was statistically analysed using IBM Statistics SPSS for Windows 23.0. The primary outcome analysed all randomized patients (on an intent-to-treat (ITT) basis) and per-protocol (PP) population. The mean pain scores at rest and their standard deviations were computed and compared using one-way ANOVA tests. VAS scale was stratified as ordinal and the significance in difference in mean scores between local and saddle groups determined by Kruskal–Wallis test at 95% Confidence interval, regarding Furthermore, the mean pain scores were further analyzed for significant differences in area under the curve (AUC) for VAS (2-sample t-test). Cross tabulation was performed and odds ratio computed for each technique of open hemorrhoidectomy. Chi-square (x