4.2. Biomarkers Responses
obesity-associated comorbidities, TG
PRE-DIABETES
It is well established in the scientific literature that physical exercise promotes greater glycemic control via an increased sensitivity to insulin action [Early identification of parameters related to lipid profile (TC and fractions: LDL-c, VLDL-c, and HDL-c, in addition to triglycerides) can substantially reduce possible cardiovascular risk, and interventions based on lifestyle changes (physical activity and food re-education) promote significant improvements in adolescents with obesity-associated comorbidities [As a final point, there was over a 70% reduction in fasting glucose for both intervention groups. Similarly, more than 20% of the adolescents with pre-diabetes returned to normal ranges. For TG, 95% of the sample was in the borderline classification, but after the intervention, these values were reduced by around ~40%. For TC, there was a reduction higher than 20% for borderline and higher classification values post-intervention for both experimental groups. For HDL-c, values increased by approximately ~40% after intervention for all groups. LDL-c returned to average values in ~60% of adolescents after intervention in the two intervention groups (conforming to 