1. Introduction
obesity, cancer
OBESITY, CANCER, DISEASES, CHRONIC DISEASES
The Japanese population has the world’s longest life expectancy but faces the challenge of extending the healthy life expectancy without developing chronic diseases. Therefore, the effectiveness of products derived from olives used in the Mediterranean diet as a potential dietary solution has attracted attention. This study examined the effects of desert olive tree pearls (DOTPs), which contain 162 times more polyphenol hydroxytyrosol than olive oil, on the cognitive function of middle-aged and older adults using the Cognitrax test. Participants (aged 51–82 years) were assigned to the DOTP intake (Japan is transforming into a super-aging society as the Japanese people have a long life expectancy, with an average life span of 84.3 years [Recently, nutrition counseling and diet adjustment have shown positive results in extending the healthy lifespan and preventing various diseases, such as cancer, obesity, and AD [Therefore, this study aimed to investigate the effects of HYD-rich DOTPs on the cognitive function of older adults. In this double-blind, randomized, placebo-controlled trial, we compared changes in the cognitive function (memory, attention, reaction time, and executive function) of middle-aged and older adults who received DOTPs and placebo for 12 weeks.