Tacrolimus
Subjects received MRG-001 on day 1, 3 and 5. Tacrolimus PK was evaluated after a subject received a single dose on day 1 and after the last dose administration on day 5. The mean whole blood tacrolimus concentration-time profiles on day 1 and day 5 are presented in Whole blood PK parameters for tacrolimus following SC administration of MRG-001 on day 1 and day 5 are summarized in The GM CThe trough concentration (CIn summary, after SC administration of a single dose on day 1 and after multiple doses to day 5 of MRG-001 0.005, 0.01, and 0.02 mL/kg (24 mg plerixafor plus 0.5 mg tacrolimus per mL), the C