INTRODUCTION
skin infections, throat, infections, ARF
ARF, AUTOIMMUNE RESPONSE, INFECTIONS, SKIN INFECTION, SECONDARY, ACUTE RHEUMATIC FEVER
Acute rheumatic fever (ARF) results from an abnormal autoimmune response to inadequately treated throat or skin infections with Group A Streptococcus (There is no specific treatment for ARF. However, the mainstay of current therapy, benzathine penicillin G (BPG), which is a long-acting formulation, is directed at preventing the colonization or infections with Although it has proven efficacy, adherence to secondary prophylaxis is low in many RHD-prevalent communities (Subcutaneous delivery of BPG is safe and potentially advantageous (