Introduction
motor deficits, stroke, disability, Stroke
STROKE, STROKE
Stroke is among the most common causes of acquired disability among adults in China (A previous randomized controlled trial investigating the effects of a home-based telerehabilitation (TR) approach on stroke patients demonstrated that a telerehabilitation program significantly improved motor function recovery and enhanced resting-state functional connectivity between the bilateral precentral gyrus (PreCG) compared with conventional rehabilitation (CR) (However, the discrepancies in regional brain activities and brain core-hub areas of functional change in stroke patients receiving TR or CR training are still unclear, which is not conducive to understanding the rehabilitation mechanisms. Neural regional properties are critical in helping us better understand the neuro-physiological and neuro-pathological situations. The amplitude of low-frequency fluctuations (ALFF) tests the signal strength in low-frequency oscillations of spontaneous brain activity and reflects regional spontaneous synchronous neural activity (As spontaneous neural activity in the brain is characterized by dynamic changes over time and the brain network always attempts to keep maintain a dynamic balance of function in constant change, static approaches may ignore the dynamic features of local neural activity and brain functional connectivity (Studies have reported that the model of spontaneous neural activity variability has been changed in patients with motor deficits after stroke, and dynamic indices of regional intrinsic neural activity might be potential methods to measure motor function (