4.6. Statistical Analysis
PBC
Statistical analysis was performed in SPSS version 23 (IBM Corp, Armonk, NY, USA), R (version 4.2.2) with R Studio (version 2022.12.0.353, PBC, Boston, MA, USA) and GraphPad Prism version 8.0.1. (GraphPad software, Inc, La Jolla, CA, USA). Continuous variables were tested for normal distribution with use of the Shapiro–Wilk normality test and visualized using normal probability (Q-Q) plots. Descriptive statistics were presented as mean (±SD) for normally distributed variables, median (interquartile range (IQR)) in case of non-normal distributions, or proportions 