Background/study design.
PCR-diagnosed malaria parasitemia
PRETERM DELIVERY, SECONDARY
This study is a secondary analysis of maternal PCR-diagnosed malaria parasitemia throughout pregnancy and ultrasound-assessed fetal growth as part of Lungwena Antenatal Intervention Study. The trial was a single-center, randomized, partially placebo-controlled, outcome assessor–blinded, three-arm clinical trial in rural Malawi. The original study hypothesis was that preterm delivery (i.e., the primary outcome of the study) and other adverse pregnancy outcomes could be reduced by IPTp with monthly SP alone or in combination with two doses of azithromycin.