Item-level analyses
Item-level analyses (i.e., item variability or frequency of endorsement) were evaluated using baseline and 36-month data, and items were further explored by sex, given the potential for certain items to differ by sex based on content. The item-level analyses included measures of central tendency (to assess the distribution of total scores), use of response categories for each item (i.e., frequency and percentage of patients in each response category), and an assessment of floor and ceiling effects at the item-level (using the sub questions, rather than the gated questions) and total score-level [