LA dysfunction and reduced exercise capacity in CHF patients
LA dysfunction, CHF
CHF
Our study of patients with CHF who received beta-blockers showed that, compared with other echocardiographic parameters, LA reservoir strain was the strongest biomarker for predicting the exercise capacity of these patients. LA reservoir strain with a cutoff value of 24.9% had high sensitivity and moderate specificity in the detection of VOA recent clinical study involving myocardial biopsy demonstrated that both LA reservoir strain and LA volume were predictors of LA fibrosis [After adjusting for LVEF, E/e′, and TAPSE, LA reservoir strain still had a good ability to predict exercise capacity (P = 0.003). Considering that the interaction between atrial phasic function and ventricular mechanics regulates cardiovascular function, our findings are not surprising. Because the increase in preload led to more severe LA dysfunction [Advanced age, BMI and sex are important factors in exercise capacity [Our study showed that LA booster strain was also an independent predictor of VOMost LV filling is completed in the early LV diastole, and LA conduit strain is more susceptible to the effect of LV diastolic function than LA booster strain. Therefore, in our study, we corrected the representative parameter of diastolic function, which is also the early diastolic E/e′. Consequently, LA conduit strain was no longer an independent predictor of VO