Funding
This work was supported by the National Natural Science Foundation (No. 72174061, NO.71704053); Suzhou Youth Science and Technology Project (NO.KJXW2020051); Suzhou Science and Technology Development Project (NO.SYSD2020164); Suzhou medical key support disciplines (NO.SZFCXK202103) and Zhejiang Health and Science and Technology Project (NO.2022KY370). The funding organizations did not participate in the design of the study, data analysis, and manuscript formation.