Clinical, laboratory and instrumental examination
acromegaly, pituitary adenoma, tumor, Proteus
TUMOR, PITUITARY ADENOMA, PROTEUS, ACROMEGALY, OSTEOPOROSIS
The diagnosis of acromegaly was verified following the recommendations of Craniographic and lateral sinus radiograph were performed in the patients using a GE Proteus XR/a system (Germany) to detect changes in the sella turcica features of pituitary adenoma (i.e., size, shape, the presence of anterior osteoporosis, and adjacent bone structures). All patients who had no contraindications for being in a magnetic field underwent an MRI of the head using the Optima MR450w 1.5T GEM device (GE, USA) to study the characteristics of the tumor (size, structure, etc.). In case of contraindications, CT of the head was performed using the Cytom 16 device (STERNMED, Germany).