Author contributions
DSS
RECRUITMENT
GMK and BJS conceptualized the study and designed the main study together with CL and DSS. BJS and GMK acquired funding for the study. AJ designed the PET experiments and data processing pipeline with input from CS, PPS, GMK, and SHK. SA was responsible for recruitment and MRI acquisition. AJ acquired the PET data with assistance from AN, KM, and AV. INP and JM were responsible for radiochemistry. VB was responsible for the processing of volumetric MRI data. AJ analyzed the data with assistance from PPS, GMK, BO, CS, SHK, and VB. AJ drafted the manuscript in consultation with GMK. All authors critically reviewed the manuscript.