IMRCs possess a stronger immunomodulatory and pro-regenerative profile than UCMSCs
PROLIFERATION
In this study, IMRCs derived from hESCs were generated through the passage of migrating cells acquired from human embryoid bodies (hEBs) using serum-free reagents (Supplementary Fig. IMRCs activated by synovial fluid enhanced chondrocytes proliferation and differentiation. In order to obtain a more comprehensive understanding of IMRCs at the protein level, we conducted a focused ELISA analysis involving 48 biologically relevant chemokines and cytokines in response to synovial fluid stimulation (Supplementary Table 