Metformin disrupts periodontal disease establishment and progression in vivo
PD, age-associated periodontal bone loss
We set out to investigate the effect of GM modulation on PD development when induced using Preventive Metformin preclinical models. After Since Metformin demonstrated a preventive potential in an induced PD model, we further investigated the effect of using Metformin on naturally occurring age-associated periodontal bone loss (Fig. 