Study design
A single-blind trial with 6-month of follow-up with parallel groups was carried out from November 2017 to June 2019. All of the procedures were reviewed and approved by the research ethics committee of Shanghai University of Sport Institute (Approval code: 2,017,017), and this study was carried out in accordance with the World Medical Association’s Declaration of Helsinki (1964). This randomized controlled trial (RCT) has been registered at the Primary Registry of International Clinical Trial Registry Platform World Health Organization “Chinese Clinical Trial Registry” [ChiCTR-INR-17013432], It should be noted that a small change was made after registration. The inclusion of WOMAC is the result of evaluating knee symptoms and functions.