Second primary tumors
tumor, esophageal adenocarcinoma, GI tract cancers, gastritis, dysplasia, head and neck surgeon, LGD, Barrett’s esophagus, reflux esophagitis, squamous low grade dysplasia
OESOPHAGEAL SQUAMOUS CELL CARCINOMA, TUMOR, ESOPHAGEAL ADENOCARCINOMA, GASTRITIS, DYSPLASIA, REFLUX ESOPHAGITIS, GASTRIC CANCER
SPTs were defined as the presence of esophageal high grade dysplasia (HGD) or esophageal squamous cell carcinoma. The detection of squamous low grade dysplasia (LGD), a precursor lesion of esophageal squamous cell carcinoma, was also monitored. All cases of LGD were reviewed by an expert team of three experienced upper GI pathologists until consensus regarding the grade of dysplasia was reached. Lesions larger than 5 mm detected during endoscopic screening with WLE, NBI, and/or Lugol’s staining, were considered suspicious for SPT or LGD. In cases of confirmed SPT, treatment was discussed in a multidisciplinary tumor board meeting with the gastroenterologist, GI surgeon, head and neck surgeon, radiologist, and oncologist. Treatment options for SPTs included endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD), surgery, and chemoradiotherapy. Other findings, including GI tract cancers such as esophageal adenocarcinoma and gastric cancer, Barrett’s esophagus, reflux esophagitis (according to the Los Angeles classification), and gastritis, were treated as per standard clinical care.