Efficacy outcomes
spleen stiffness
In this study, treatment with the 2 highest doses of BI 685509 dose-dependently decreased mean portal–systemic shunt fraction. The HepQuant SHUNT test uses the hepatic uptake of cholate from the systemic and portal circulations to assess liver function and portal blood flow.Although spleen stiffness may identify a portal pressure decrease in response to NSBBs,