Feature group selection
The Feature group columns in Table Figure Analysis of which feature groups are selected for the targets of interest when feature group selection is used. The coloured bars show the frequency that each feature group was selected for each target across the repeated CV splits. For each target three sub-segmentation feature sets were used (indicated by upper right box) and the text on the right-hand side indicates which feature group was selected when a single model was estimated from the whole data set – in most cases this corresponds to the feature group with the widest coloured bar. EvoST = evolutionary subtypeWith the Proposed pipeline, the shape feature group was selected in > 50% of CV splits for one or more ROI sets for Sarcomatoid change, RVI, IVC invasion, Overall Stage, wGII Max, and Loss 9p21.3, while MeshVolume was selected for Linear EvoST in > 90% of CV splits. For Sarcomatoid change and Overall Stage, the shape feature group was selected in > 60% of CV splits, buts only for models built using the whole/high/low ROI set.Table 