Institutional Review Board Statement
The WAS study was conducted in accordance with the Declaration of Helsinki, and approved by the Ethics Committee of the University Hospital of Wuerzburg (182/08, approved on 16 December 2014). The rodent model was conducted according to the guidelines of the Declaration of Helsinki and approved by the local regulatory authority (Regierung von Unterfranken, Wuerzburg, Germany, AZ: 55.2-2532-2-467). All experiments were performed in accordance with German and European laws and regulations (TierSchG, TierSchVersV, Directive 2010/63/EU).