Clinical investigation
Clinical investigation was performed at baseline and at 3-month, and 6-month follow-up and included a medical examination that included cardiorespiratory and abdominal examinations was performed. In addition, weight was measured with a digital scale (Tanita BWB-800, Tanita Corp., Japan), height was measured with a wall-mounted stadiometer (SECA model 264, Seca, Germany) (only at baseline), waist circumference was measured using a measuring tape, and blood pressure was measured with a digital automatic monitor (Omron M3 Comfort, Omron, Japan).