Strengths and limitations
migraine
MIGRAINE, RECRUITMENT
This study has the strength of being among the first to investigate the long-term effects of self-applied tDCS on brain perfusion in episodic migraineurs and comparing these data to the migraine frequency. However, there are some limitations. First, the sample size was relatively small—we had to halt recruitment due to difficulties finding participants—and comprised migraineurs with and without aura that may have differing alterations in cortical perfusions. Second, we only included episodic migraineurs with a relatively high migraine frequency. As a result, this study will have missed changes in brain perfusion due to infrequent migraine attacks if these differ from those found in our sample. Lastly, our sample comprised mostly female migraineurs and thus may not generalise to male patients.