1. Introduction
atherosclerotic cardiovascular diseases
CVD, ATHEROSCLEROTIC CARDIOVASCULAR DISEASE
Most atherosclerotic cardiovascular diseases can be prevented by modifying lifestyles, including unhealthy diets. Eggs contain important carotenoids that may impact cardiovascular risk. The lipid nature of eggs can improve the bioavailability of other carotenoids, such as Annatto (Most atherosclerotic cardiovascular diseases (CVD) can be prevented by acting on behavioral risk factors, such as unhealthy diets and physical inactivity [Colombia is a country with medium to low incomes and whose poverty has increased with the pandemic [For nearly 50 years, dietary cholesterol and eggs were thought to contribute to increased plasma cholesterol and CVD risk [Follow-up studies have shown that egg consumption has been associated with a lower mortality risk [In addition to protein and cholesterol, eggs also contain important carotenoids (antioxidants), such as lutein and zeaxanthin. Higher plasma concentration of these two carotenoids associated with higher concentrations of large LDL and HDL particles have been reported in people consuming three eggs/day for 12 weeks, compared to an egg substitute [Carotenoids, the natural pigments of fruits and vegetables [Given that the controlled evaluation of the effects of egg consumption and its enrichment with carotenoids (from Annatto) on cardiovascular health in the Colombian population is very limited, the objective of this study was to evaluate the association between egg consumption and eggs enriched with Annatto (