Discussion
IgAN, non-IgAN, primary glomerular disease
RENAL FAILURE, THROMBOTIC MICROANGIOPATHY
IgAN is the most common primary glomerular disease worldwide and the main cause of renal failure, requiring renal replacement therapy [Thrombotic microangiopathy is common in IgAN [After multivariate analysis of clinical laboratory indicators, IgA and urine occult blood were independent predictors for distinguishing IgAN from non-IgAN, consistent with previous studies [Our research has some limitations: 1. The sample size was relatively limited, and the results may have some deviation. In future research, we will further expand the number of cases. 2. All data were from one institution, and only data from one equipment supplier were used. 3. The model has not been verified in an external independent cohort.In conclusion, we propose a nomogram diagnosis model based on DL radiomics and clinical features displayed by SMI. This model extracts the features from SMI-based images through a convolutional neural network and fuses these features with the radiomics and clinical features to distinguish IgAN from non-IgAN. The results showed that the DL radiomics model based on SMI could effectively distinguish IgAN patients from non-IgAN patients. This model has good clinical applicability. The model provides an easy-to-use and personalized tool for noninvasive diagnosis of IgAN and can help physicians develop a more beneficial treatment plan for patients.