Patients
Parkinson’s, PD, movement disorder
MOVEMENT DISORDER, DISORDERS, MOVEMENT DISORDER, -20
Patients were screened in five university hospital movement disorder departments in France (Lyon, Clermont-Ferrand, Saint Etienne, Grenoble, and Nice). We included patients diagnosed with PD at least 1 year previously and in accordance with the Movement Disorder Society criteria, who were aged [30–80] years, and who weighed [40–95] kg. ICD symptoms had to start after PD onset and initiation of DRT. The Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease-Rating Scale (QUIP-RS) was used to assess the presence and severity of ICDs. The QUIP-RS is a screening instrument for ICDs [Approval from the institutional ethical standards committee on human experimentation (Comité de protection des personnes Ouest IV -Nantes) was obtained before study initiation and the trial was done in accordance with the Declaration of Helsinki and the International Conference on Harmonisation Good Clinical Practice Guidelines. All patients provided written informed consent before randomisation (EudraCT number 2019-000165-20). The study was registered (NCT03552068) on clinicaltrials.gov.