Conclusions
fatigue, ESKD, kidney disease, pain
KIDNEY DISEASE
The TĀCcare trial is the first randomized clinical trial, to our knowledge, for people with kidney disease where the intervention is targeted toward multiple symptoms rather than a single symptom. Our results showed that among patients undergoing hemodialysis, a 12-week CBT-based stepped collaborative care intervention can offer clinically significant improvements in fatigue and pain. Leveraging telemedicine to deliver CBT that targets symptom clusters during hemodialysis sessions may provide a scalable and resource-efficient approach to improve patient-centered outcomes among patients with ESKD who are undergoing long-term hemodialysis.