Image preparation and feature extraction
erosion of the tumour, tumour
TUMOUR
Pre-surgical CE-CT scans were obtained during the nephrographic contrast phase from four different scanner vendors using a range of standard of care imaging protocols detailed in supplementary information Table SImage volumes were resampled using bilinear interpolation to give 1 × 1 × 5mm voxels, after which multi-slice segmentations were drawn by a clinical fellow (SS) to cover the whole tumour and checked/corrected by a consultant radiologist with 7 years’ experience (DAD). Two different image sub-segmentation methods were explored: sub-segmentation into visually apparent high and low enhancing sub-regions, and erosion of the tumour masks by 10mm to generate core and rim masks, see Fig. Example tumour sub-segmentations and histograms: One hundred five radiomics features were computed in compliance with IBSI guidelines using pyradiomics v3.0.1 [