Assessments
bleeding, investigator-reported, Stroke, stroke, haemorrhage
BLEEDING, STROKE, ADVERSE EVENTS, STROKE, HAEMORRHAGE, EVENTS
Age, sex, ethnicity and prior antiplatelet therapy (none, aspirin, clopidogrel, dipyridamole, other) were recorded at baseline. The severity of index stroke was assessed with the National Institutes of Health Stroke Scale (NIHSS, scores range from 0 to 42 with higher scores indicating a more severe neurological deficitParticipants were seen at days 7 (on treatment) and 35 (end of treatment) to determine whether any outcome or bleeding events had taken place and to assess treatment compliance. Final follow-up was performed centrally by blinded assessors at 90 days by telephone from the coordinating centre in each country. If the participant could not be contacted, a paper version of the form was sent by post. Data pertaining to recurrent cerebrovascular events were captured at days 7 and 35 (investigator-reported), in any serious adverse events, at day 90 telephone follow-up and in a general practitioner questionnaire after day 90. Expert adjudicators blinded to treatment assignment validated and categorised the primary outcome, haemorrhage and investigator-reported serious adverse events. Any participants who violated the protocol were still followed up in full and included in intention-to-treat analyses.