Study setting and samples
MAY, HUMAN PAPILLOMA VIRUS
The study used anonymised, archived urine and serum samples collected as part of an ongoing clinical trial of human papilloma virus (HPV) vaccine dosing schedules in The Gambia (the HANDS trial; At the time of enrolment to the parent trial, before any trial interventions had taken place, urine and serum were collected from participants (≥ 15 years) or their mothers/female guardians (for participants < 15 years) for HPV genotypic and seroprevalence testing. The samples used in this study came from those who provided additional informed consent for the future use of retained samples for other ethically approved research. Specimens were collected between September 2019 and February 2021 and tested for the STI prevalence study in May 2021.