Introduction
T2D, diabetes
DISEASE, SECONDARY, TYPE 2 DIABETES, PREMATURE, DIABETES
Globally, Type 2 Diabetes (T2D) is a cause of a major disease burden [Despite the potential benefits of lifestyle interventions in T2D-prevention, premature intervention cessation and stress are leading to sub-optimal intervention benefits [Premature intervention cessation is the result of a complex interaction between intervention inputs, individuals, and context variables [Identification of pathways to successful weight-loss maintenance is challenging owing to the interconnectivity and interchangeability between factors, in where factors can have both direct and indirect influence on the outcomes [In this study, health-related QoL, social support, use of primary care, and mood at the start of a lifestyle intervention were examined. It was hypothesized that these variables function influence intervention cessation and chronic stress, both of which are associated with less favorable weight-loss and weight-loss maintenance outcomes [Higher risk of adverse consequences from T2D has been associated, for example, with sex (men), non-Caucasian ethnicity, and lower SES, which, in turn, are associated with lower likelihood of enrolment and higher likelihood of intervention cessation [Lower SES (measured as income) and higher chronic stress have been associated with worse weight-loss outcomes for both men and women and with overall lower QoL [Beyond premature intervention cessation, chronic stress has been identified as one of the key factors hindering weight-loss and weight-loss maintenance efforts in lifestyle interventions [In these secondary analyses, data were analyzed from a group-based T2D-prevention intervention PREVIEW (PREVention of diabetes through lifestyle Intervention and population studies in Europe and around the World) with weight-loss and weight-loss maintenance phases [