Conclusions
OPMDs, malignant disorder
RECURRENCES, OPMDS
To the best of our knowledge this is one of the few studies investigating the in vivo use of OCT in OPMDs.In vivo use of this device by the generalist physician, with adequate training, will improve its diagnostic performances during the long-term follow-up of the patient with potential malignant disorder reserving the biopsy with histopathological traditionally examination if a worsening or malignant evolution pattern is observed.The Oral Medicine specialist should use in vivo-OCT not only for short-medium follow-up for patients most at risk of malignant evolution but also to monitor outcomes of medical or surgical therapy and any recurrences of OPMDs at a non-invasive and ultrastructural level.Further studies with large sample series will be needed to validate the precise values of the thicknesses of different epithelial layers during OCT evaluation to obtain more significant results with reference to the specific sites of the various districts of the oral mucosa.