Patients/demographics
Median age was 73 years and, thus, remarkably higher than in the COMFORT-II trial, and 53% of patients were male, a slightly lower percentage than in COMFORT-II. Median body mass index (BMI) was 24.3. Around 9% and 14% of patients were active or previous smokers, respectively. Patients who dropped out did not significantly differ from patients who had completed the study regarding sex or BMI; however, study completers tended to be younger (70 years vs 74 years) and non-smokers (4.5% vs 10%). For detailed pt demographics, please see Table General characteristics of patients in arm A (Abbreviations: 