Physiological measures
BLOOD
Physiological changes were measured to assess whether the drug was active or not during the WM tests. Blood pressure (BP), temporal vein temperature (Temp) and heart rate (HR) were measured in triplicate five times each day to follow the time course of the drug and placebo effects on Systolic BP (SBP), Diastolic BP (DBP), HR, and Temp. BP (mmHg) and HR [in beat per minute (bpm)] were measured. The consecutive five physiological testing times were 0, 60, 110, 210, and 370 min post-d-amphetamine administration, while 0, 60, 210, 300, and 390 min post-caffeine administration.