Exercise intervention effect on vessel lumen size and CBF
Relative to the control group, the increase in ICA and MCA M1 vessel lumen diameter was significantly greater between baseline and 16-week measurements in the exercise group than in the control group (ICA mean between-group difference: 0.1 mm [95 % CI, 0.01–0.18]; MCA M1 mean group difference: 0.05 mm [95 % CI, 0,01–0.10]). There were no significant group differences in the change in MCA M2, ACA, BA, and PCA (Vessel lumen diameter change with exercise per vessel segment.There were no voxel-wise differences between randomised groups in the change in CBF during the exercise intervention period.