Design and ethical consideration
Ethical approval for this randomized, controlled, parallel-groups field trial was granted by the Research Ethics Committee of the Faculty of Dentistry, Alexandria University (#0274-07/2021). This trial was registered in the clinicaltrials.gov registry (#NCT05642494). The research procedures, risks and benefits were explained to the parents, and they were asked to sign an informed consent form. The study was conducted in accordance with the Helsinki declaration [