Conclusion
toxicity, testicular cancer
TESTICULAR CANCER, EVENT, EVENTS
In this explorative analysis, patients who started the exercise intervention during BEP-chemotherapy better preserved their pulmonary function (DLCO, FVC), measured directly post-chemotherapy and 1-year post-intervention (DLCO, KCO). This coincided with less increase in factor VIII and vWF, measured directly post-chemotherapy. These data support a beneficial role of a physical exercise intervention during BEP-chemotherapy on pulmonary and vascular toxicity in patients with testicular cancer and warrant further investigation. Three patients in group A developed BIP, compared to none in group B. Two patients in group B developed a vascular event, compared to none in group A. The small numbers of patients with BIP and vascular events warrant caution when interpreting these data.