Effect of 6-Month PrEP Dispensing With HIVST on Study Outcomes at 12 Months Among All Participants and Participant Subgroups
REGRESSION
Abbreviations: HIVST, HIV self-testing; LB, lower bound; NA, not applicable; PrEP, preexposure prophylaxis; RD, risk difference; SOC, standard of care; TFV-DP, tenofovir-diphosphate.Participants randomized to these intervention groups received 6-month PrEP dispensing with interim HIVST (either oral-fluid or blood-based) with semiannual clinic visits.In noninferiority analyses, 1-sided 95% CIs of −10% or greater were interpreted as noninferior. RDs were measured using binomial regression models with identity links, adjusted for study population at enrollment (eg, men in HIV serodifferent couples, women in HIV serodifferent couples, and women singly enrolled).All follow-up visits assigned as 12-month visits by study staff and that occurred prior to extensive follow-up procedures (extensive follow-up occurred when a participant had not returned for a 12-month visit by 15 months after enrollment) were included.