Strengths and Limitations
Some limitations should be considered. OAB symptom complexity can be influenced by many factors, such as the type of fluid intake. However, we did not have information about the participants’ consumption of different types of fluids, e.g., caffeine-containing drinks, which are known to affect voiding habits. The sample size in our study was small, making it difficult to obtain statistical conclusions and account for heterogeneity among participants. We formerly aimed for 100 participants, but due to problems finding women meeting study criteria, we enrolled a lower number. Additionally, compliance was not based on measuring the residual volume of the RCE and placebo. The use of a randomized, double-blinded, placebo-controlled study design entails both limitations and strengths for the study. It results in a lower number of women included in each treatment group; however, it also enables the investigation of a placebo effect. Another strength is that we evaluated OAB symptom effects using both ICIQ questionnaires in combination with a fluid intake and voiding diary.