Statistical analysis
carcinoma
TRADITIONAL SERRATED ADENOMA, CARCINOMA

The difference in pooled accuracy, sensitivity, and specificity of optical diagnosis between the POLAR system and endoscopists was compared using two-sided McNemar tests with continuity correction. The PPV and NPV were compared using the weighted generalized score and Fisher’s exact test. If the histopathology outcome was carcinoma, traditional serrated adenoma, normal mucosa, inflammatory lesion, or missing, the lesion was excluded from the diagnostic accuracy analysis. For all outcomes on diagnostic test accuracies, 95 %CIs were calculated. The statistical analysis for the other analyses can be found in
