TCT+PRIME Show Durable Gains in Emotion Recognition
schizophrenia spectrum disorders, schizophrenia
Our results indicate significantly greater improvement in emotion recognition, and greater improvement at the trend level, although this was not statistically significant, in global cognition in the TCT+PRIME group relative to the CG+PRIME group. In emotion recognition, both groups showed improvement from baseline to posttraining; however, these effects were only durable at the follow-up in the TCT+PRIME group, with a medium effect size. In global cognition, the total sample showed a significant gain; however, within-group contrasts revealed that only the TCT+PRIME group showed improvement from baseline to posttraining, with an effect size in the medium range, whereas the CG+PRIME group showed negligible change. At follow-up, the gains in the TCT+PRIME group showed some durability with an effect size in the small range; however, these results did not reach statistical significance. Both groups also showed durable gains in attention, likely owing to the attentional demands of the TCT and CG exercises.The TCT+PRIME group results are consistent with those of our prior study of cognitive training combined with social cognition training versus cognitive training alone (TCT only) in 111 participants with schizophrenia spectrum disorders [Our prior studies on cognitive training versus a CG in chronic schizophrenia and recent-onset schizophrenia have also shown larger effects at posttraining and follow-up [Finally, the differences in these effects across studies could also be the result of differences in the measures. In our prior studies, the MATRICS Consensus Cognitive Battery was administered in person [