Ethical considerations
The respective review boards at the Taipei Medical University Joint Institutional (N201909018) approved the study. We provided all participants with an information sheet about the study prior to enrolment and obtained signed consent forms. Participation was fully voluntary. We assured the participants about safety issues, informing them of their right to withdraw or discontinue participation at any time without penalty, and that the collected data would remain strictly confidential and would be used only for research purpose. No personal information would appear in the research reports.