INTRODUCTION
death, musculoskeletal PASC, Sars‐CoV‐2 damages, microcirculation deterioration, coronavirus disease 2019
CORONAVIRUS DISEASE 2019, SEQUELAE, DISEASE
The novel coronavirus disease 2019 (COVID‐19) pandemic has generated great illness, death, distress, and undefined sequelae on our society (Cucinotta & Vanelli, According to Centers for Disease Control and Prevention (Centers for Disease Control and Prevention, The mechanism by which Sars‐CoV‐2 damages muscles is not yet fully understood. There is speculation that microcirculation deterioration may be a factor (Trinity et al., Physical therapy programs have been proposed for the management of musculoskeletal PASC (Righetti et al., A number of studies support the effectiveness of electrical stimulation (E‐Stim) to improve LE vascular health (Gorgey et al., Given the poor exercise tolerance and potential for unhealthy HR2S in individuals with PASC, safe and effective solutions for improving HR2S and supporting functional recovery are needed. Therefore, the purpose of our study was to investigate the potential benefits of E‐Stim in improving the recovery of individuals with musculoskeletal PASC. Our main hypothesis is that E‐Stim therapy will improve both HR2S and LE muscle endurance in this population. Moreover, we hypothesize that there will be a positive correlation between muscle perfusion and endurance, indicating that E‐Stim may improve both aspects of muscle function in individuals with musculoskeletal PASC.