Outcomes
AMS
The primary outcome was the DE at post-sleep testing. As this study is a nested trial, sample size calculation was performed for the primary outcome of the main trial, the incidence of AMS [Secondary outcomes included the analysis of the DE during immediate recall and 60° adaptation. To assess overnight learning, the differences in DE between post-sleep recall and adaptation respectively immediate recall were compared. Analogously, immediate learning was evaluated by the difference between adaptation and immediate recall. Furthermore, as a measure of correct test execution, the probability of performing valid movements and reaction time were analyzed.