Noninferiority analyses (reactive vs active intervention group)
cancer stage
REGRESSION, ONCOLOGY
The reactive and active intervention groups were comparable in terms of baseline summary score (mean = 76.6 [SD = 16.0] in the reactive group; mean = 75.8 [SD = 14.1] in the active group; Multivariable linear regression analysis for health-related quality of life from baseline to 15 weeks reactive vs active intervention group including confoundersEORTC quality of life score and functioning scales: higher score = better quality of life and/or functioning. EORTC symptom scales: higher score = worse symptoms. T1 = 15 weeks; B = unstandardized beta; ES = Cohen’s Clinical relevance according to guidelines of Cocks et al. (Multivariable analyses were controlled for histology, treatment, cancer stage, Eastern Cooperative Oncology Group Performance Status, baseline score, and transfer sequence of the hospitals.After controlling for confounders, between the reactive and active intervention group in the multivariable linear regression analyses, no statistically or clinically significant differences were found between the summary score (unstandardized beta [B] = 0.51, 95% confidence interval [CI] = -3.22 to 4.24, ES = 0.06; 