Changes in Sodium:Creatinine Ratio
Because there is potential for human error to lead to incomplete collection of 24-hour urine output, we, therefore, analyzed the sodium:creatinine ratio in the collected urine samples (Figure 
Changes in urine sodium:creatinine ratio over time (mean±SEM).
There were significant differences at each subsequent time point after randomization between intervention and control groups in urine sodium:creatinine ratio. At 3 months after randomization, the urine sodium:creatinine ratio was 8.4 (±2.9) mmol/mmol for the intervention group, compared with 9.9 (±4.1) mmol/mmol for the control group (