3.4. Effect of Conditioning (Study Day 3 vs. Day 1)
bloating, nausea
Pre-ingestion and ingestion phase. No significant differences were detected in the sensations measured before and during meal ingestion on the study day 3 as compared to day 1 in both groups (Postprandial phase. In the control group, sham conditioning (duodenal sham infusion on the previous day) did not modify the postprandial experience as compared to the first study day. By contrast, in the test group, aversive conditioning (duodenal lipid infusion on the previous day) significantly impaired postprandial well-being, and this was associated with a trend to increase in bloating and mild abdominal discomfort, without changes in satiety, nausea and mood (