Safety and tolerability
Headache, fever
ADVERSE EVENTS, ADVERSE EVENT, ADVERSE EVENT
All participants in the high- and low-dose immunization groups experienced at least one grade 1 adverse event after the first immunization. Headache and fever were the most common adverse event for participants that received a high- or low-dose immunization (Table Systemic and local solicited adverse events throughout the studyOnly possibly or probably related adverse events are depicted. Adverse events of control participants and unsolicited adverse events are shown in Additional file Adverse events after immunization 1. 