Introduction
Cataract, blindness, ® IOL, vision impairment worldwideGlistenings are small, PCO
CATARACT, SEPARATION, IOL, BLINDNESS
Cataract is one of the leading causes of blindness and the second leading cause of moderate-to-severe vision impairment worldwideGlistenings are small (1–33 µm) fluid-filled microvacuoles that appear in IOLs when exposed to an aqueous environment as a result of phase separation caused by water developing in microvoids due to temperature fluctuationsThe purpose of this multicentric clinical trial was to evaluate the clinical acceptability, long-term PCO formation, and the glistening rate of the HOYA Vivinex™ XY1 IOL (HOYA Surgical Optics, Tokyo, Japan) compared to the Alcon AcrySof® IOL (Alcon Laboratories, Fort Worth, Texas, USA), within a follow-up period of 3 years.The study hypothesis proposed that the HOYA Vivinex™ XY1 IOL, compared to the AcrySof® IOL, would demonstrate a reduction in glistening, as well as comparable PCO rates, visual acuity (VA), and contrast sensitivity.