Statistical analysis
death
Survival was calculated from the date of diagnosis until the date of death from any cause or the date of the last follow-up. GraphPad Prism 9.0 and SPSS 22.0 (IBM, New York/USA) statistical software was adopted, and data that did not fit a normal distribution are presented as median and range. T-test was used for data that fit a normal distribution and homogeneity of variance, and Wilcoxon rank sum test was used for others. The median follow-up time was estimated with the use of Kaplan-Meier methods. All tests were two-sided, and a P value of 0.05 was considered to indicate statistical significance.