Author contributions
XD and NL contributed to the conception and design, acquisition, analysis and interpretation of the work and drafted the manuscript. CZ, YW, KS, HP, SW and ZS contributed to data acquisition. YG contributed to data analysis and revised the manuscript. TZ and WW revised the manuscript. All gave final approval and agreed to be accountable for all aspects of the work, ensuring integrity and accuracy. All authors read and approved the final manuscript.