Discussion
diabetic, peripheral neuropathy, diabetes
PERIPHERAL NEUROPATHY, HIGH BLOOD PRESSURE, DIABETES
The current research aimed to determine the effectiveness of oral clonidine and gabapentin on peripheral neuropathy in diabetic patients. The results indicated that combining clonidine and gabapentin significantly affected peripheral neuropathy more than a single gabapentin consumption. To the best of our knowledge, to date, no previous investigation has examined the effectiveness of a combined treatment of gabapentin and clonidine (oral solution) on peripheral neuropathy among individuals who have diabetes. Below is information from other studies with similar results. Fulas et al. [Clonidine is a high blood pressure medication that can affect the alpha-adrenergic receptors and imidazoline as an agonist [There were limitations in the present study, which include: not having a group that was prescribed only clonidine. In this regard, it is suggested to consider a group for clonidine alone in future research. Another limitation of the research was the use of a purposeful sampling method, which led to a reduction in the generalizability of the results. In this regard, it is suggested to use a random sampling method to select participants in future research.