Study arm differences in neurotoxicity
neurotoxicity, depression, peripheral neuropathy, cognitive complaint
REGRESSION, EVENTS, PERIPHERAL NEUROPATHY
Logistic regression, adjusted for gestational age stratum, was used to compare the Immediate and Deferred INH arms with respect to cognitive complaint, poor sleep quality and peripheral neuropathy at each analysis visit. Given the small number of probable depression events, exact logistic regression was used for this outcome measure. Because potential interaction effects between timing of INH initiation and EFV exposure were of particular interest, a supplemental analysis summarized neurotoxicity by EFV exposure.