Datasets and respective aims
Cancer
CANCER
We assessed the time trend of incidence by extracting the annual incidence of CRNENs from 1975 to 2019 from the SEER Research Plus Data 9 registry. Since our study was limited to the 7th AJCC staging, we only extracted data from the SEER database of stage II-IV CRNENs from January 2010 to December 2016 to investigate survival and prognostic factors. An independent validation cohort of 62 patients who had been diagnosed with CRNENs between January 2010 and January 2016 at the Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College was also collected for validation. For this study, the patient information was stored in the hospital database with their written consent. This study was exempted from ethical requirements by the ethics committee of Cancer Hospital, Chinese Academy of Medical Sciences.