Main results
HF decompensation, HF, COPD, decompensation
COPD, DISEASE, DISEASES
The present study reported diagnostic models that achieved a good detection capacity for exacerbation of COPD or HF decompensation (S and E greater than 80%). Although the S and E were slightly lower than those of models in two other studies (Vamos et al.Another important result was that the underlying disease (COPD or HF) did not influence the development or diagnostic performance of the models; thus, to our knowledge, this is the first study to report diagnostic models of decompensation potentially applicable to patients affected by COPD and by HF, which may be relevant given the increasing proportion of patients affected by both pathologies. However, our study can only be considered preliminary at this point because the trial size was modest and the design was not robust enough to confirm that this result is generalizable. Therefore, this result warrants further investigation. As a hypothesis, we propose the coexistence of pathophysiological mechanisms in the decompensation of both diseases, with HR, Ox and their relationship serving as parameters that could represent a relevant common denominator for decompensation of both pathologies. Ox has already shown considerable utility in the detection of acute HF in previous studies