References
STM
INS
Correlation of baseline C-Pep with BMI (Pearson correlation coefficient r = 0.32; p = 0.004).Correlation of Δ C-Pep in STM with BMI (Pearson correlation coefficient r = 0.23; p =0.043).HbA1c changes on early insulin treatment (INS) vs. oral antidiabetics-only (OAD) groups during 12 months of follow-up.Differences in BMI-adjusted STM-stimulated relative C-peptide increase in short-term early insulin treatment vs. oral antidiabetics-only group after 3 and 12 months.Age, HbA1c, Baseline C-Pep, ΔC-Pep, absolute increase in C-peptide; HOMA-IR, homeostatic model assessment of insulin resistance;HOMA-B, homeostasis model assessment of β-cell function.Baseline demographic and metabolic characteristics in INS and OAD groups.FPG, fasting plasma glucose; TC, total cholesterol; TG, triglycerides.BMI and serum lipids during study follow-up in the INS groupTC, total cholesterol; LDL-C, LDL-cholesterol; HDL-C, HDL-cholesterol; TG, triglycerides; AIP, atherogenic index of plasma.BMI and serum lipids during study follow-up in the OAD group.TC, total cholesterol; LDL-C, LDL-cholesterol; HDL-C, HDL-cholesterol; TG, triglycerides; AIP, atherogenic index of plasma.Beta cell function during study follow-up in the INS group.ΔC-Pep, absolute increase in C-peptide; ΔC-Pep%, relative increase in C-peptide;PCPG, postprandial C-Pep to postprandial glucose ratio; BMDCP- BMI-adjusted relative ΔC-Pep.Beta cell function during study follow-up in the OAD group.ΔC-Pep, absolute increase in C-peptide; ΔC-Pep%, relative increase in C-peptide;PCPG, postprandial C-Pep to postprandial glucose ratio; BMDCP- BMI-adjusted relative ΔC-Pep