Recruit participants
cardiovascular and cerebrovascular diseases, psychiatric, alcohol dependence, epilepsy
MAY, ALCOHOL WITHDRAWAL, EPILEPSY
From May 2022 to October 2022, 57 male patients with alcohol dependence who were hospitalized in the Fifth Department of Psychiatry, Second Affiliated Hospital of Xinxiang Medical University were recruited and divided into the study group (n = 29) and the control group (n = 28) according to a random number table.Inclusion criteria: ① meet the diagnostic criteria for alcohol dependence in ICD-10; ② aged 18 ~ 50 years, Han nationality, primary school education or higher, right-handed; ③ acute withdrawal treatment ≥ 7 days, Clinical Alcohol Withdrawal Symptoms Rating Scale (CIWA-Ar) < 8; ④ normal vision or corrected vision; ⑤ normal hearing or corrected hearing; ⑥ no history of abuse of other psychoactive substances (except tobacco). Exclusion criteria: ① serious physical illnesses such as cardiovascular and cerebrovascular diseases; ② serious neurological illnesses such as epilepsy; ③ combined with other psychiatric illnesses; ④ unable to adapt to the virtual reality environment. Dropout criteria: ① subjects were unwilling to continue treatment and withdrew on their own; ② unable to complete treatment as prescribed for various reasons; ③ had missing data due to instrument failure.The study protocol was reviewed and approved by the Ethics Committee of the Second Affiliated Hospital of Xinxiang Medical University, and all study subjects were fully informed of the purpose of the study and signed the informed consent form.