References
cerebral vascular disease, sepsis, Sequential organ failure, COPD, RTT
ACUTE MYOCARDIAL INFARCTION, PCT, CVD, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, COPD, OXIDATIVE STRESS, AMI, SEPSIS, PVC
Electronic selection by computer was used to divide patients into blocks with a total of 5 groups of 131 patients in total. In the group Vit C (n = 27) patients were studied, in the group with Vit E (n = 24), NAC (n = 24), MT (n = 26) and (n = 29) patients remained without treatment.PCR = C-reactive protein; Vit C = vitamin C; Vit E = vitamin E; NAC = n-acetylcysteine; MT = melatonin; Tx = treatment, Values median. Test statistician: Kruskal-Wallis. PCT = procalcitonin; Vit C = vitamin C; Vit E = vitamin E; NAC = n-acetylcysteine; MT = melatonin; Values are expressed as mean ± SD. Test Statistic: One-Way Kruskall Wallis between groups NAC = N-acetylcysteine, MT = Melatonin, Tx = without treatment, SOFA = Sequential organ failure assessment. Values are expressed as median (p25–p75 quartiles), Test statistic: One-way Kruskall Wallis Showed oxidative stress markers in plasma of patients with sepsis before and after of antioxidant therapy.Enzymatic pathway that comprised the activity of the glutathione-S-transferase, glutathione reductase, glutathione peroxidase, Thioredoxin, superoxide dismutase, peroxidases and glutathione before and after antioxidant therapy. Abbreviations: Vit C = Vitamin C, Vit E = Vitamin E, NAC = n-acetyl cisteine, MT = Melatonin.Showed some markers of the non-enzymatic pathway such as Vitamin C, Thiols and selenium levels before and after antioxidant therapy.Demographic characteristics and comorbidities by treatment group at admission in ICU.Abbreviations: Vit C = vitamin C, Vit E = vitamin E, NAC = N-acetylcysteine, MT = melatonin, Tx = without treatment, COPD = chronic obstructive pulmonary disease, CVD = cerebral vascular disease, AMI = acute myocardial infarction, CNS = central nervous system, SAPS II = Simplified Acute Physiology Score, APACHE II = Acute Physiology and Chronic Health Evaluation, SOFA = sequential organ failure assessment, NUTRIC: Nutrition Risk in the Critical III.Condition of the patients at the time of admission, according to the assigned antioxidant therapeutic management and the type of standard management and ventilatory assistance.Abbreviations: Vit C = vitamin C, Vit E = vitamin E, NAC = N-acetylcysteine, MT = melatonin, Tx = COPD = chronic obstructive pulmonary disease, CVD = cerebral vascular disease, PVC = peripheral venous catheters, AMI = acute myocardial infarction, CNS = central nervous system, IMV = intermittent mandatory ventilation, SAPS II = Simplified Acute Physiology Score, APACHE II = acute physiology and chronic health evaluation, SOFA = sequential organ failure assessment, MAP = mean arterial pressure, RTT = referral to treatment. Treatment statistics, Kruskal–Wallis and Fisher. The values are expressed as median (Min-Max).