Conflict of interest
Stock
Amy Jo Chien: Research funding to institution: Merck, Puma, Amgen, Seagen. Michelle E. Melisko: Research funding to institution: Astra Zeneca, Novartis, KCRN Research, Puma, Seattle Genetics. For spouse: Speaker bureau/honoraria: AstraZeneca, Genentech, Gilead. Stock Ownership: Merrimack. John Park: Consulting/honoraria: AstraZenica, Genentech, Diichi, Gilead. Equity/stock ownership: Merrimack Pharma. Hope S. Rugo: Research support for clinical trials through the University of California: Pfizer, Merck, Novartis, Lilly, Roche, Daiichi, Seattle Genetics, Macrogenics, Sermonix, Boehringer Ingelheim, AstraZeneca, Astellas and Gilead. Honoraria from: Puma, Samsung, Mylan, Chugai, Blueprint, and NAPO. The remaining authors, declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.