Procedures
ADVERSE EVENTS
Included patients were assessed daily during hospitalization, from day 1 (day of inclusion) through day 29 and, after discharge on follow-up visits days 10, 15 and 29. Clinical status was assessed daily using an eight-category ordinal scale and the National Early Warning Score, and, at specified time points, using SOFA-score. Serious adverse events were recorded until a final follow up at 60 days.