Ethics approval and consent to participate
We aimed to recruit 120 individuals who met inclusion criteria and signed the IRB-approved informed consent to participate [60 in each group].All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study protocol was approved by the University of Michigan Institutional Review Board: HUM00195591.