Introduction
tumour, Adrenocortical carcinoma
CORTEX, TUMOUR, ADRENOCORTICAL CARCINOMA
Adrenocortical carcinoma is a rare tumour arising from the cortex of the adrenal gland, with few therapeutic options.On the basis of this evidence, the development of an effective adjuvant treatment is an unmet clinical need. Post-surgical adjuvant mitotane treatment was introduced into clinical practice more than 50 years ago.Following that study and subsequent recommendations of international guidelines to use adjuvant mitotane in most patients,