Flow of participants.
HED
CON, control group; DCON, diet control group; MED, moderate exercise dose group; HED, high exercise dose group; ITT, intention-to-treat; PP, per-protocol.Baseline characteristicsData are presented as means and standard deviations or medians with IQR (25Units for AUC glucose and paracetamol are presented in mmol/l × h, and units for AUC insulin, C-peptide, GLP-1 and GIP are presented in pmol/l × h. SGLT2i, sodium/glucose cotransporter 2 inhibitor; DPP4i, dipeptidyl peptidase 4 inhibitors; ARB, angiotensin ll receptor blocker; ACEi, angiotensin-converting enzyme inhibitor; CCB, calcium channel blocker; IGI, insulinogenic. *