2.3. Levels of ECM Biomarkers Correlated to Demographic and Clinical Parameters
pain, osteopenia, fractures, joints, osteoarticular disease
OSTEOPENIA
Levels of the ECM biomarkers at baseline in patients stratified by sex, age, cAKUSSI, and antiresorptive treatment (bisphosphonates, vitamin D, systemic glucocorticoids, and calcium) are shown in Levels of CTX-I were elevated in males, and levels of CTX-II/Creat were elevated in older patients and in patients with higher cAKUSSI. The cAKUSSI was also higher in older patients (When looking at baseline correlations of the biomarkers of bone and cartilage remodelling with the components of the cAKUSSI related to bone and joint health (osteoarticular disease in joints and spine, pain in joints and spine, number of experienced adult fractures, and osteopenia of hips [bone density in g/cmALP levels at baseline were higher in older patients and in patients with higher cAKUSSI (