Funding
This study was supported by grants from the National Science and Technology (no. 2009ZX09103-100, 2013ZX09402201-002, 2017GSF218106, 2018ZX09303015, and 2021ZD0204004). Shandong Luye Pharmaceutical Co., Ltd, is the sponsor, it provided the clinical trial funds and ansofaxine ER tablets and its placebo for the clinical trial. The sponsor fulfilled the responsibilities according to the Good Clinical Practice without interfering with implementing clinical trials.