Findings
cord blood transfusions
In this cohort study of 23 randomized neonates, cerebral near-infrared spectroscopy was monitored before and after 42 packed red blood cell (PRBC) transfusions in 17 preterm neonates, of which 22 units were standard PRBCs from adult donors and 20 were PRBCs obtained from allogeneic cord blood. A higher regional oxygen saturation and a lower fraction of oxygen extraction were recorded after adult transfusions compared with cord blood transfusions, suggesting that adult hemoglobin was associated with an overexposure to oxygen in cerebral tissue.