Study interventions
AKI, hyperkalemia, metabolic acidosis
METABOLIC ACIDOSIS, FLUID OVERLOAD, PULMONARY EDEMA
In the early-strategy group, RRT was started within 12 h after the diagnosis of AKI. In the delayed strategy group, RRT was started 48 h after the diagnosis of AKI, or as soon as possible if at least one of the following pre-specified emergency criteria occurred before 48 h: hyperkalemia (serum potassium level > 6.5 mmol/liter), metabolic acidosis (pH < 7.15) or fluid overload refractory to diuretics with pulmonary edema.The choice of RRT technique (intermittent or continuous) was at the discretion of each study site, and investigators were encouraged to follow international guidelines.