Statistical analysis
throat
REGRESSIONS
Descriptive statistics were calculated to characterise the sample. For all analyses below, we report the mean difference (MD) in scores for NVPs versus HTPs alongside 95% confidence intervals (CI), with positive MD values indicating greater endorsement for NVPs and negative values greater endorsement for HTPs.Linear regressions were conducted to examine the differences in (i) cigarette-related withdrawal symptoms after using NVP and HTP, adjusted for urges or mood and physical symptoms (respectively) before using each product. Similarly, to examine differences between NVP and HTP in (ii) product satisfaction, (iii) intention to switch to NVP/HTP, (iv) perception, (v) attitudes, (vi) reasons for switching to NVP/HTP, linear regressions were conducted. The intercept/constant of these regressions were the estimate, and 95% CIs were calculated by multiplying the standard error appropriate critical value from the t-distribution. All the regressions were adjusted for period.Statistical analysis was conducted on complete cases in SPSS Statistics version 27. The protocol and analysis plan were pre-registered on Open Science Framework (An exploratory analysis examined potential differences between the two NVPs used (Juul and Aspire PockeX) in product satisfaction and throat irritation. We examined this because prior studies suggest that the aerosol from NVPs that use nicotine salts e-liquid, such as Juul, is less harsh to inhale than aerosol from products using freebase nicotine, like the Aspire PockeXSocio-demographic and smoking-related characteristics.SD = standard deviation. Cigarette dependence was measured with the Fagerstrom test of cigarette dependence, scores 1–9 with higher scores presenting higher cigarette dependence. Motivation to stop was measured with the motivation to stop scale, scores 1–7 with higher score presenting higher motivation to quit cigarette smoking.