Reasons for preference
On first ranking, 222 (52%) chose the preferred drug because of “feeling better”, whereas 164 (38%) chose it due to “lack of side effects”, with 44 (10%) unclassifiable. Canagliflozin was most likely to be chosen because of “feeling better”, whereas pioglitazone was most likely to be chosen because of “lack of side effects” (After being fed back their HbA1cs and weight, 125/457 (27%) changed their preferred drug. Most patients (76%) changed because of the HbA1c result (55% HbA1c alone, 21% HbA1c and weight) while 29% changed because of weight (8% weight alone, 21% HbA1c and weight). There were clear differences between the drugs (