Seven-day follow-up after each vaccination
headache, fever
ADVERSE EVENTS, EVENTS
Local AEs were mostly pain/limitation of limb movement. Fifty individuals (37%) reported pain/limitation of movement 81 times across the three vaccine doses (Solicited, vaccine related mild to moderate adverse events on Days 1-7 after each vaccine dose.For systemic events, in Cohorts 1 and 2, most events (20 events in total) were headache (13; n = 7 from BK-SE36/CpG arm, n = 4 from control arm). In Cohort 3, fever was reported on 19 occasions in the BK-SE36/CpG arm (n = 13) but only once in the control arm. All were, however, of short duration (≤1 day); and most events were mild except for 3 Grade 2 headache events post Dose 3 in Cohort 1 (n = 1 from BK-SE36/CpG arm, n = 2 from control arm).