Nugent score increases with Cu-IUD use and strongly correlates with Cu-IUD induced alterations in absolute bacterial abundance
To relate individual bacterial concentrations to broader health metrics such as clinical BV diagnosis, we calculated the sum of the concentrations of bacteria that were significantly altered by each contraceptive. DMPA-IM and LNG implant use did not result in significant shifts in the concentrations of any bacteria after adjustment for multiple comparisons and thus were not correlated with Nugent score. Conversely, the concentrations of bacteria whose abundance was altered after 6 months of Cu-IUD use (Fig. 