Longitudinal Analysis
depression, Anxiety Depression, anxiety
The mixed models for repeated measures did not show clinically significant differences at M12 or at M24 for SF-36, HADS anxiety, and ZBI (Caregivers adjusted mean change over time (mixed model for repeated measures) in Short Form-36 physical component summary, mental component summary, in Hospital Anxiety Depression Scale, and Zarit Burden Interview in each allocation group (Informal Carers of Elderly study, France, 2015–2019).Note: SIG, Supportive intervention group; CG, control group; M12, M24, Month 12, 24; PCS, physical component summary; MCS, mental component summary; CI, Confidence interval. MID was fixed at 5 points for Short Form-36 PCS and MCS scores, 1.32 points for Hospital Anxiety Depression Scale anxiety score, 1.4 points for Hospital Anxiety Depression Scale depression score, and 7.2 points for Zarit Burden Interview score. In bold: significant MID.Mixed models for repeated measures used for longitudinal analysis included all timepoints until M24 and included the following effects: randomization group, time, allocation-by-time interaction, adjusted on baseline score, and baseline score-by-time interaction.