Acknowledgements
The authors thank Alison London, Marjo Rajalaakso, Sini Marttinen, Sirpa Soisalo, Inga-Lill Åberg, Iina Vuoristo, Justyna Kolakowska, Heikki Metsola and Janne Ravantti for excellent technical support. The authors acknowledge the computational resources provided by the ELIXIR node, hosted at the CSC–IT Center for Science, Finland. Graphical abstract was created with BioRender.com.