Inclusion criteria
NON-PROLIFERATIVE DIABETIC RETINOPATHY, MACULAR EDEMA
Patients aged of 20–60 years old, with evidence of non-proliferative diabetic retinopathy, and centers involving macular edema (average macular thickness of 300–500 μm) who agreed to use additional topical treatments to the standard intravitreal injection of anti-VEGF were included.