Safety
decreased appetite, fatigue
EVENTS, EVENT, MALIGNANT NEOPLASM PROGRESSION, SPINAL CORD COMPRESSION
All patients reported a treatment-emergent AE (including two grade 4 events [spinal cord compression and condition aggravated] and one grade 5 event [malignant neoplasm progression]). None of the grade 4 or 5 AEs were considered drug-related. The most frequent drug-related AEs were fatigue (70.0%) and decreased appetite (50.0%; Supplementary Table 