Results of the included studies
Di Rienzo, Hapalia, Di
A summary of the selected studies is represented in supplementary file 2 and Table Summary of the evidenceFavoring: 10 RCT (Hapalia, Balasubramanian, Shapiro, El Tahan, Singh, Mularczyk, Ozkiris, Di Rienzo, Gülšen, Chauhan); 2 NRCT (salam, Bidaye); 1 prospective cohort (Kim); 1 retrospective cohort (Gul)Against:No difference: 1 metanalysis (Sun)Favoring: 1 RCT (singh), 1 prospective cohort (kim -microdebrider-)Against:No difference:Favoring: 8 RCT (Hapalia, Ozkiris, balasubramanian, El Tahan, Singh, Mularczyk, Gülšen, Chauhan); 2 NRCT (Salam, Bidaye), 1 retrospective cohort (Gul)Against: 1 RCT (Shapiro); 1 prospective cohort (Kim -microdebrider-)No difference: 1 metanalysis (Ya-Lei Sun); 1 retrospective cohort (Sjogren)Favoring: 8 RCT (Hapalia, balasubramanian, Di Rienzo, El Tahan; Gülšen, Chauhan, Bhat, Huang); 2 NRCT (Salam, Bidaye); 1 retrospective cohort (Gul)Against:No difference: 1 metanalysis (Ya-Lei Sun)Favoring: 1 retrospective cohort (Sjogren)Against: 1 retrospective cohort (Bhandari)No difference: 1 metanalysis (Lee)Favoring: 1 metanalysis (Ya-Lei Sun); 5 RCT (Hapalia, Singh, Mularczyk, Gülšen, Chauhan); 1 1 NRCT (Bidaye)Against:No difference: 1 NRCT (Salam); 2 RCT (Shapiro, El Tahan)Favoring: 2 RCT (Di Rienzo, Huang)Against:No difference:Favoring: 1 RCT (Ozkiris)Against:No difference:Favoring: 1 RCT (Gülšen)Against:No difference: 1 RCT (Bhat, Huang), 1 NRCT (Salam)Favoring:Against:No difference: 1 RCT (Huang)Favoring: 1 retrospective cohort (Sjogren)Against:No difference:The search strategy retrieved 20 studies, 2 metanalysis [The review, excluding the 2 metanalysis, encompassed a total population of 8375 participants. The mean sample size per study was 465.28 patients. The largest sample size was reported by Bhandari et al [Regarding the different surgical techniques, excluding the two meta-analyses, 18 studies performed coblation (Only 13 of the 20 selected studies provided their mean age. Given this limitation, the mean age adjusted for sample size was 6.37 years, with the youngest mean age being 4.58 years by Mularczyk et al [The mean follow-up adjusted by sample size was 96.39 days, being 730 days the longest follow-up (Bhat et al.) [