Results
NVD
THYROID
All 57 newborns were screened by the national programme, but 16 parents declined the thyroid function tests on their babies at day 7 (Demographic and clinical characteristics of the offspring born in the SELFI study who were screened under the New Zealand newborn metabolic screening programme and those who also had a thyroid function test (TFT) at Day 7.Data are the mean ± standard deviation or n (%).LSCS, lower segment caesarean section; NVD, normal vaginal delivery; TFT, thyroid function test.


Thyroid function tests were performed on time at day 7 in 76% of subjects and within nine days in 90%. The remaining four tests were performed between 11 and 20 days. The delay from the proposed date was caused by the government-imposed lockdowns during the COVID-19 pandemic (Results of thyroid function tests in the SELFI Study offspring.FT3, free triiodothyronine; FT4, free thyroxine (tetraiodothyronine); Q1, quartile 1 (25




There were no observed associations between maternal peak TSH or peak UIC and offspring parameters at birth or on Day 2 TSH (Linear associations between maternal urine iodine concentrations (UIC) and peak thyroid-stimulating hormone (TSH) levels during pregnancy and offspring outcomes.Data are the Pearson’s correlation coefficients (r) and respective p-values, with statistically significant associations at p<0.05 shown in bold.UIC values were log-transformed to approximate a normal distribution.FT3, free triiodothyronine; FT4, free thyroxine (tetraiodothyronine); and TSH, thyroid-stimulating hormone.Linear associations between maternal peak urine iodine concentrations (UIC) during pregnancy and Day 7 thyroid function parameters (serum) in the offspring: Maternal peak TSH levels during pregnancy were also associated with lower Day 7 FT3 levels in the offspring (When potential interactions between maternal peak TSH and peak UIC during pregnancy were examined, there was evidence of an interaction between those two parameters and their associations with Day 7 serum FT3 (p=0.018), but not TSH (p=0.87) or FT4 (p=0.62). For FT3, the lowest Day 7 levels were observed in the offspring of mothers with both high peak TSH and high peak UIC (