Statistical analysis
blood loss
BLOOD LOSS
The sample size was calculated on the basis of the difference in the primary outcome, namely, total blood loss. Based on pilot data from 24 patients who received unilateral primary TKA with TXA was given intravenously before tourniquet compression between December 2020 and September 2021, the mean total blood loss was 421 ml (SD 272). In the study of TXA was given intravenously before tourniquet release, the mean total blood loss was 642 ml (SD 242) [