Closed-loop therapy period
diabetes
EVENT, DIABETES
Before the closed-loop therapy period commenced, participants underwent a 1-h to 2-h training session with the study team on the use of the insulin pump, continuous glucose monitoring and closed-loop system. Once participants were deemed competent to use the devices, the closed-loop system was initiated and continued for 8 weeks. The usual insulin therapy of participants was discontinued, but all other medications were continued as directed by their clinical team without interference from the study team. The insulin pump delivered faster-acting insulin aspart continuously as directed by the algorithm, without prandial boluses or carbohydrate announcement.The study did not interfere with the usual activities or dietary intake of participants. Other diabetes therapies were continued throughout the closed-loop therapy period. Participants were given 24-h access to a study helpline in the event of any study-related issues. At the end of the closed-loop therapy period, devices were removed and the usual insulin therapy of participants was restarted.