Introduction
heart failure, reduced left ventricular ejection, HF
HEART FAILURE
It is well-established that in patients with heart failure (HF) with reduced left ventricular ejection fraction (HFrEF), an integrated HF clinic program including implementation of disease-modifying drugs and devices, patient education in self-care, and referral for physical training improves long-term clinical outcomes [In The NorthStar study, patients with HFrEF receiving optimal medical therapy did not benefit from continued follow-up in a specialized HF clinic compared with follow-up in primary care during a median follow-up of 2.5 years, even in high-risk patients, defined as patients with an N-terminal pro-B-type Natriuretic Peptide (NT-proBNP) ≥1000 pg/ml [Therefore, in a 