Cognitive Impairment and Overall Symptom Response Following 8 Weeks of Treatment
Mediation models focused on executive function and response inhibition because they were most significantly impaired in the cognitive biotype positive subgroup. Lack of change in cognitive control performance was a significant mediator of the association between pretreatment cognitive biotype and lack of overall symptom relief following treatment (indirect effect a × b = −0.24; bootstrapped 95% CI, −0.49 to −0.02) (