Study Site and Recruitment
VLBW, congenital anomalies
PRETERM DELIVERY, PLACENTA ACCRETA, PLACENTAL ABRUPTION, PLACENTA PREVIA WITH HEMORRHAGE
The Extrauterine Placental Transfusion in Resuscitation of VLBW Infants (EXPLAIN) trial (German Clinical Trial register: DRKS00017041; ClinicalTrials.gov: Pregnant individuals with a gestational age more than 23 6/7 weeks and an estimated fetal weight of less than 1500 g who were at risk of preterm delivery were eligible for this study. Parents were approached for informed consent prior to delivery. Only infants born by cesarean delivery were eligible for this study. Exclusion criteria included vaginal delivery, fetal or maternal risk (ie, compromise, emergency cesarean delivery, or general anesthesia), placental abruption or placenta previa with hemorrhage, placenta accreta or increta, monochorionic multiples, congenital anomalies, and lack of consent to the study from parents.