Results
COPD, septic shock
CHRONIC OBSTRUCTIVE PULMONARY DISEASE, COPD, SECONDARY, SEPTIC SHOCK
The baseline demographics of the 109 eligible septic shock patients are shown in Baseline characteristics of all patients (APACHE II: Acute Physiology and Chronic Health Evaluation II scores; SOFA: Sequential Organ Failure Assessment scores; MAP: mean artery pressure; CVP: central venous pressure; GFR: glomerular filtration rate; Ccr: creatinine clearance rate; Scr: creatinine levels; BUN: blood urea nitrogen; COPD: chronic obstructive pulmonary diseases.The primary outcomes showed that there was no statistically significant difference in the Scr, BUN, GFR, or Ccr between the intervention group and the control group on admission and on days 3, 7, and 14. The urine output was higher in the intervention group on days 3, 7, and 14 (Primary outcomes in a trail of low dose furosemide and aminophylline in patients with septic shock.GFR: glomerular filtration rate; Ccr: creatinine clearance rate; Scr: serum creatinine levels; BUN: blood urea nitrogen.The secondary outcomes showed that the APACHE II score, MAP, hematocrit and albumin were not significantly different between the intervention group and the control group on admission and on days 3, 7, and 14, while CVP on days 7 and 14, SOFA, CRRT time, ICU mortality, hospital mortality and 28-day mortality were significantly lower in the intervention group than in the control group (Comparison of 28-day mortality between the control group and the intervention group.Secondary outcomes in a trail of low dose furosemide and aminophylline in patients with septic shock.APACHE II: Acute Physiology and Chronic Health Evaluation II scores; SOFA: Sequential Organ Failure Assessment scores; MAP: mean artery pressure; CVP: central venous pressure.The cumulative fluid balance was markedly lower in the intervention group on days 3 and 7, while there was no significant difference on day 1 compared with the control group (Comparison of cumulative fluid balance on days 1, 3 and 7(Cumulative fluid balance volume (ml): cumulative fluid intake volume-cumulative fluid output volume.