3.2. Blood Glucose and Insulin
fasting blood glucose
The fasting glucose levels of all of the participants were in the normal to borderline range (fasting blood glucose level ≤ 125 mg/dL) during all of the periods in Studies 1 and 2. In Study 2, comparisons of the three conditions using linear mixed-effect models revealed a treatment effect for the change in blood glucose and serum insulin. The comparison of the three groups analyzed by the mixed-effect model revealed a significant difference in the tAUC among the three groups in both blood glucose and serum insulin. Furthermore, the tAUC for blood glucose was significantly lower in the Dose C group and the Dose D group than in the Placebo group. Furthermore, the Dose D group had a significantly lower tAUC value than the Placebo group.