Interventions
At first, before allocation, the principal investigator (FY) explained the aims of this project to eligible participants who were admitted to the ICU and have been hemodynamically stable and received supplemental nutrition (first 24–48 h) via enteral tube feeding with 25 kcal/kg/day energy and obtained written informed consent. Nutritional support was administered in the bolus method, 7 times a day. Then, patients in the intervention group received 3 doses of 1 g Participants in different treatment arms received all common medications and the standard treatments, and our intervention was used as adjunctive therapy. All of the participants were visited routinely on all intervention days and probed for any undesirable effects by a physician and reported. Return empty drug vials were used for assessing adherence.