Study design
postoperative pain, postoperative bleeding, tamponade
POSTOPERATIVE BLEEDING
The NoTamp study was a German multicenter randomized controlled trial (RCT) designed to compare the effects of perioperative placement of a rectal tamponade on postoperative pain development and occurrence of surgically relevant postoperative bleeding in open hemorrhoidectomy [The trial duration for each randomized patient was 7 days. There was no blinding of participants, physicians, nurses, or outcome assessors. The study received full ethics committee approval of the University of Witten/Herdecke, Germany, and was conducted in accordance with Good Clinical Practice guidelines, with regular external monitoring.