Authors’ contributions
WL
ADZ, MvdL, JD, WL, LR, WEvS, and MVdE conducted the clinical trial. AE and NJ measured the biomarkers. PF, AE, and CST conducted the statistical analysis and prepared all figures and tables. CST, AE, and MVdE drafted the manuscript text. All authors critically reviewed the manuscript. The author(s) read and approved the final manuscript.