Abbreviations:
RESTLESS LEGS SYNDROME
restless-legs-syndromerestless-legs-syndrome quality of life questionnairestatistical package for social sciencesWillis-Ekbom diseaseMT and JS contributed equally to this work.Trial registration: This study was registered in the German Clinical Trial Registry (number DRKS00029960) on August 09, 2022.Ethics approval and consent to participate: This study was reviewed by the ethics committee of Charité-Universitätsmedizin Berlin (reference number: EA2/132/22). Written informed consent is obtained from all patients. All procedures in this study are in accordance with the Declaration of Helsinki.Consent for publication: Not applicable.The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.The authors have no conflicts of interest to disclose.Funding for this study was provided in part by the Karl and Veronica Carstens Foundation, which has made grants available as part of the Young Clinician Scientists grant program (scholarship recipient: Dr. med. Julia Siewert). The foundation had no influence on the design, methodology, conduct, analysis, or publication of the study.How to cite this article: Kubasch J, Ortiz M, Binting S, King R, Dietzel J, Nögel R, Hummelsberger J, Willich SN, Brinkhaus B, Teut M, Siewert J. Hydrotherapy and acupressure in restless legs syndrome: A randomized, controlled, 3-armed, explorative clinical trial. Medicine 2023;102:26(e34046).