Intervention and standard care
®, orthostatic exercise
PRESSURE ULCERS
The early orthostatic exercise consisted of daily (weekdays) head‐up tilt on an ERIGO® tilt‐table (Hocoma) to 70° for 20 min as this was perceived to be feasible when planning the trial. Vital signs and intracranial pressure were monitored during tilting. In case of a critical reduction in either blood pressure (systolic <80 mmHg; diastolic <50 mmHg) or cerebral perfusion pressure (<50 mmHg), or an increase in either intracranial pressure (>25 mmHg) or heart rate (>180 bpm), the participant was moved to 0° until stable before returning to 70° (Riberholt et al., Treatment in the standard care group was decided by the treating physician, nurses, and therapists. Mobilization could be a part of the standard care but occurred at a much smaller scale than in the intervention group. The major focus was respiratory optimization and re‐positioning to prevent pressure ulcers, and tilt‐table mobilization was not a part of standard care. For more detailed information we refer to the original publication (Riberholt, Olsen, Søndergaard, et al., 