Background
hypoxia, Diabetes
BLOOD, OBESE, HYPOXIA, DIABETES
Edited by: Jonatan Ising Bagger, Steno Diabetes Center Copenhagen (SDCC), DenmarkReviewed by: Chrysovalantou (Chrisa) Eleni Xirouchaki, Monash University, Australia; Ewa Śliwicka, Poznan University of Physical Education, Poland†These authors have contributed equally to this workN-lactoylphenylalanine (Lac-Phe) is a new form of “exerkines” closely related to lactate (La), which may be able to inhibit appetite. Blood flow restriction (BFR) can lead to local tissue hypoxia and increase lactate accumulation. Therefore, this study investigated the effects of combining Moderate-intensity Continuous Exercise (MICE) with BFR on Lac-Phe and appetite regulation in obese adults.