Data collection, management and analysis
An instruction manual for data collection and patient follow-up along the intervention process will be created. This manual will include the methodology of data collection and a detailed description of all the instruments used to obtain the study data. An initial protocol will be used for data entry, which will include specifications aimed at minimizing coding errors. All the technical personnel involved will undergo training sessions on the field work to harmonize data collection. Standardized protocols for quality control and data filtration will be developed. A centralized database will be designed for the data of the different participating centers. A central analytical plan will be developed, and the group coordinator of the project (An expert in research methodology and statistics will be in charge of designing the methodological focus and the statistical techniques that will be used to analyze the data obtained of each variable. Briefly, descriptive statistics will be calculated for the overall sample and between the experimental groups taking into consideration the gender perspective. Subsequently, the corresponding parametric or non-parametric analyzes will be carried out to establish the minimum intra- and inter-group changes of the variables analyzed. Missing cases will continue in the final analysis, however, they will provide less information and decrease the variance of the estimated effects to a lesser extent than the existing cases at each assessment stage.An α value ≤ 0.05 will be considered to indicate statistical significance. The final analysis of the study will be fully described and differences between the enrolled experimental groups will be presented to determine the effectiveness of the exercise programs.