2.9. Copy Number Variation Association with PFS
number loss
INTERACTION
We investigated whether CNA in metastatic lesions could be associated with patient outcome. Using a log-rank statistic test, we identified 9 and 29 regions of copy number loss and gain, respectively, associated with PFS (permutated Three genes, GPR52, PTGS2, and MYC, are classified as drug resistance genes in the Drug-Gene Interaction Database (DGIdb) [