1. Introduction
Coffee cherry pulp, a major waste product from coffee manufacturing, contains polyphenols with antioxidant activity. However, its clinical safety and health benefits are unclear. This randomized, double-blinded, placebo-controlled trial evaluated the safety and potential efficacy of coffee cherry pulp juice concentrate. A total of 61 participants were randomly divided into a study group (Coffee pulp, which refers to the skin and the pulp of coffee fruit, is the main residue produced during coffee production [Coffee pulp can be processed into various food commodities, such as jam, juice, concentrate, jelly, flavoring, and alcoholic beverages [