Study design
BEST
A monocentric prospective and randomized trial was conducted between February 2020 and December 2021 in a tertiary academic hospital (Erasme hospital, Brussels, Belgium). The protocol was approved by the ethical committee of the institution (Ref. Nr: P2019/617), performed in accordance with the declaration of Helsinki, and registered on ClinicalTrials.gov (number: NCT05257382, date: 25/02/2022). Written informed consent was obtained from each participant.Participants were randomly assigned in one of the following groups:◦ "Endoscopy suite": ENB procedures were performed in an endoscopy room under standard X-ray fluoroscopy guidance.◦ "CBCT suite": ENB procedures were performed in a room equipped with a CBCT (Philips Allura Clarity FD20 scanner (Philips, Best, The Netherlands)).The allocation of the participants to each of these arms was performed by the principal investigator using a simple randomization technique by random draw (randomization 1:1).