Results
Participant characteristics are shown in Table Participant characteristics within treatment groups.There was no evidence for a CBD*time interaction with 400 mg CBD compared to placebo in either the adjusted or unadjusted models, indicating that 400 mg CBD did not significantly affect anandamide levels relative to placebo. For 800 mg CBD vs placebo there was evidence for a CBD*time interaction from day 0 to day 28 in the adjusted model (Estimated marginal means of anandamide levels in the 400 mg CBD group by week.Estimated marginal means of anandamide levels in the 800 mg CBD group by week.Estimated marginal means of anandamide levels in the placebo group by week.Within-group changes in anandamide levels from day 0 to day 28.