Conclusions
Plasma and RBC folate levels were higher in children and adolescents receiving dolutegravir‐based ART than on other ART regimens. Further studies are needed to clarify the mechanisms of these interactions and the clinical implications of increased blood folate levels.ODYSSEY ClinicalTrials.gov registration number, NCT02259127; EUDRACT number, 2014–002632‐14, the ISRCTN number, ISRCTN91737921.