Interaction between DEX prophylaxis and HA exposure
To test the concept that DEX could counteract the HA-induced transcription signature in PBMCs, we looked for interactions between DEX prophylaxis and HA exposure using three complementary approaches. The first approach was comparing the sequence set lists modulated by each intervention. Of the 2607 sequences modulated at least 2-fold by HA exposure, and the 167 sequences modulated at least 2-fold by DEX prophylaxis, there were only 24 shared by both lists (