Acute autonomic effects of 100 µg lysergic acid diethylamide (LSD), 100 mg 3,4-methylenedioxymethamphetamine (MDMA), and the LSD + MDMA combination (100 µg+100 mg) over time.
LSD, MDMA, and the LSD + MDMA combination increased blood pressure, heart rate, and body temperature compared with placebo. MDMA alone and the LSD + MDMA combination increased blood pressure and heart rate more compared with LSD alone. The substances were administered at t = 0 h. The data are expressed as the mean ± SEM in 24 subjects. The corresponding maximal responses and statistics are shown in Table 