Effect of ACE genotype on lower limb fat and muscle strength.
Limb composition was determined by DXA in 72 women and 58 men. The individuals were genotyped for the ACE I/D polymorphism and the effect of polymorphic variation on body composition and strength was determined. The II/ID genotypes were associated with a higher lower limb fat mass than the DD genotype in women but not in men (A). In men but not women, the II/ID genotypes were associated with greater quadriceps muscle strength than the DD genotype. (p Values calculated by Mann-Whitney U test).