Neurological test battery results
orthostatic tolerance, Orthostatic hypotension
ORTHOSTATIC HYPOTENSION
The cognitive battery revealed relatively normal mean scores in the overall cohort, with women having better scores in the MoCA (27.1 ± 4.5 vs. men 26.0 ± 5.3; Distribution of scores in primary domains of function. The distribution of individual scores (open circles) with the mean value indicated via the shaded bar and the threshold for abnormality (dotted line) with the percentage of the total cohort falling above/below this threshold and meeting criteria for abnormal function for (A) the Montreal Cognitive Assessment (% abnormal based on Z‐score of 1.5 SD or below after normalization), (B) the MDS‐UPDRS part III (% abnormal based on total score > 4), (C) the Brief Smell Identification Test (% abnormal based on total score ≤ 8), (D) the SCOPA‐AUT (% abnormal based on total score > 13), (E) Farnsworth‐Munsell 100 color vision test (% abnormal based on total score > 100), (F) the Alternate Tap Test for participants dominant hand (% abnormal based on total score < 165).Mean motor test and examination scores were in the normal range (Table A relatively large proportion of participants had autonomic impairment as assessed by orthostatic tolerance testing. Orthostatic hypotension was present in 27.7% of the cohort (defined by a systolic and/or diastolic blood pressure drop of >20/10 mm Hg, respectively, after 3 min of standing), with 13.3% having values in the severe range (i.e., systolic and/or diastolic drop >30/15 mm Hg); there were no differences between men and women.Average FM‐100 scores in non‐color‐blind participants were 143.6 ± 97.6, indicating 74% of the cohort was abnormal, with women showing slightly better mean color vision (119 ± 89 vs. 149 ± 101; 