Data availability
Data from the trial are stored in an online secure database hosted by the NHSBT Clinical Trials Unit. The protocol, consent form, statistical analysis plan, definition and derivation of clinical characteristics and outcomes, training materials, regulatory documents and other relevant study materials are available online and were published elsewhere. The datasets generated during analysis will be available upon reasonable request from the NHSBT Clinical Trials Unit after de-identification (text, tables, figures and appendices) 9 months after publication and ending 5 years after article publication. Data will be shared with investigators whose use of the data has been assessed and approved by an NHSBT review committee as a methodologically sound proposal. The NHSBT Clinical Trials Unit can be contacted at CTU@nhsbt.nhs.uk. The Clinical Trials Unit will be able to provide a copy of our data-sharing policy and arrange a data use agreement, which will need to be signed. All data use agreements will be in line with the consent given by participants upon agreeing to take part in the trial.