Fermentation of prebiotic fibers with human stool increases short-chain fatty acid (SCFA) production.
PD
Stool obtained from PD patients had a lower concentration of total SCFA than stool obtained from healthy controls (HC) (left panel, Student’s Subsequently, a stool fermentation assessment was performed to determine the ability of different fibers (resistant starch, rice bran, resistant maltodextrin, inulin) to promote the growth of specific bacterial groups and influence SCFA production. Hierarchical clustering and heatmap visualization of stool microbial community structure revealed that each fiber enriched specific bacterial taxa, with limited overlap observed between the fibers. Bacteria enriched by the prebiotic fibers included those from the genus 