Detection of KIT and PDGFR Gene Mutations
tumor
TUMOR, GIST
Tissue samples were provided: fifteen 5-μm thick white slices of GIST tumor tissue.Peripheral blood sample provision: blood samples, 5 mL anticoagulant and 5 mL non-anticoagulant, will be collected before treatment and at the first efficacy assessment after treatment.Tissue samples were used for KIT/PDGFRA genetic testing: peripheral blood samples were used to explore predictors of possible association with anlotinib. The genetic detection sites included exons 9, 11, 13, 14, 17, 18 of KIT gene and exons 12 and 18 of PDGFRA.