Study infusion
Prior to infusion, participants underwent an ultrasound examination (Acuson S3000 and Acuson 18L6 probe, Siemens Medical Solutions, Malvern, USA) to assess SC fat using a validated protocol (The prescribed BPG dose was transferred to a 30 mL syringe (JMS Co. Ltd, Hiroshima, Japan) and delivered into a single injection site on the lower anterior abdomen over a period of up to 30 minutes using a spring-driven syringe infusion pump (Springfusor30, Go Medical Industries Pty Ltd., Subiaco, Australia), a variable flow control device (VersaRate Plus, EMED Technologies, El Dorado Hills, California, USA) and a 22 G SC catheter (BD Saf-T-Intima, BD Medical, Mississauga, ON, Canada). Two milliliters of 1% lignocaine was used to prime the system and provide local anesthesia prior to commencing the infusion.