Statistical analysis
All of the data used in this analysis is available in Whether the alleles were in Hardy-Weinberg equilibrium was determined by Chi squared test using allele frequencies published for the European Caucasian population (rs10783486, MAF = 0.26 and rs2854464, MAF = 0.26) [The threshold for statistical significance (alpha) was taken as 0.05. All available data were used for each comparison and no manipulations were performed to include missing values for individual tests. As this analysis is exploratory no adjustments were made for multiple testing.