Noninferiority Plot for Caries Arrest and Prevention at 2 Years
caries arrest
Whiskers indicate the 95% CI comparing the experimental group with the active control for caries arrest and prevention. The dashed line denotes the noninferiority limit. If the right-sided 95% CI does not exceed this threshold, then noninferiority is determined. This is equivalent to a 1-sided test.With imputed data for children with caries arrest (n = 874), the estimated control proportion of caries arrest was 0.47, yielding a corresponding odds ratio (OR) noninferiority margin of approximately 0.6. Comparisons of the estimated treatment effect OR to 1/OR noninferiority margin indicates that the experimental treatment remained noninferior for caries arrest (OR, 1.49; 95% CI, 0.91-2.44) (