3.3. MAP3K1 Level Is Decreased in SLE Patients and Involved in CD4+ T-Cell Proliferation
lupus
PROLIFERATION, LUPUS
Next, we detected MAP3K1 expression in PBMCs from healthy controls and SLE patients and found that MAP3K1 was significantly decreased in SLE patients. We then evaluated the diagnostic ability of MAP3K1 in SLE using ROC and obtain the AUC on MAP3K1 with a value of 0.847 (Previous studies have shown aberrant T-cell proliferation in SLE patients and lupus mice [