Hospital Care Costs Models and Impacts of Adverse Events on Hospital Care Costs
vascular death, death, stroke, cancer, heart failure
ADVERSE EVENT, ADVERSE EVENTS, CANCER, STROKE, EVENTS, EVENTS, HEART FAILURE
The results from the specification tests and comparison of predictive performance of different model specifications are reported in Table Additional Annual Hospital Costs Associated With Selected New Adverse Events From the UK and US (Medicare) Health Care PerspectivesData of 21 820 REVEAL study participants recruited in Europe and North America contributed to this analysis of hospital inpatient care costs. Hospital admissions were costed using UK National Health Service or US Medicare program reference costs, respectively. All hospital costs at 2019 prices. Events referred to Statistically significant (Statistically significant (Other interactions (MI and vascular death, nonhemorrhagic stroke and vascular death, and incident cancer and nonvascular death) were observed for both UK and US annual hospital costs.In the United Kingdom, the highest additional annual hospital costs were in the year with noncoronary revascularization £5830 [95% CI, 5437 to 6248], nonfatal MI with urgent CRV £5614 [95% CI, 5179 to 6089], urgent CRV without MI £4674 [95% CI, 4254 to 5149], and nonurgent CRV without MI £4651 [95% CI, 4338 to 4988]. Additional hospital costs were also observed in the year with heart failure admission, nonhemorrhagic stroke, MI without CRV, incident cancer, nonhemorrhagic stroke, and nonvascular or vascular death (Table Most of the adverse events were also associated with additional long‐term annual hospital costs, with admission for heart failure, noncoronary revascularization, and incident cancer associated with the largest long‐term impacts from both the US and UK perspectives (Table Results were similar in scenario analyses that used only UK and only North American participants when reporting additional annual hospital costs associated with events, although uncertainty increased due to smaller number of contributing events (Table An Excel program for the implementation of the health‐related QoL and hospital care cost models accompanies the article (Data 