Statistical Analysis
REGRESSION
Analyses were restricted to the modified intention-to-treat population, defined as all randomized participants who initiated the study intervention. Time to symptom improvement, symptom resolution, and return to usual health were compared between arms using the Gehan-Wilcoxon test for censored data. Time-averaged total daily symptom score was compared using a 2-sided Wilcoxon rank sum test.The proportion of participants with nasopharyngeal and anterior nasal SARS-CoV-2 RNA less than the LLOQ was compared between arms across study visits using Poisson regression with robust variance adjusted for entry logThe proportion of participants experiencing a new grade 3 or greater TEAE through day 28 and the proportion with symptom progression were compared between arms using log-binomial regression and summarized with an RR and All comparisons used a 2-sided 5% type I error without adjustment for multiple comparisons; 