Participants
HAEMODYNAMIC INSTABILITY
The study was conducted at a single tertiary centre intensive care unit within a general hospital. Participants were recruited between March and October 2021. The inclusion criteria were as follows: all patients hospitalized in a general ICU; aged over 18 years; on mechanical ventilation for a minimum of 12 hours and a maximum of 48 hours. The exclusion criteria were as follows: haemodynamic instability (systolic blood pressure < 90 mmHg or mean blood pressure < 60 mmHg) [