Overall Survival After Treatment Failure in the CAO/ARO/AIO-94, CAO/ARO/AIO-04, and CAO/ARO/AIO-12 Trials
tumor
REGRESSION, TUMOR
The log-rank test and a Cox proportional hazards regression model were used to assess statistical significance. The statistical tests were 2-sided. HR indicates hazard ratio.We also examined the association of tumor location (low, 0-5 cm; middle, >5-10 cm; high, >10 cm of the anal verge) and sex with treatment failure. Site of treatment failure did not differ by tumor location (eTable 1 in Median OS after treatment failure tended to be higher among male (median, 31 months [IQR, 27-36 months]) than female patients (median, 26 months [IQR, 19-37 months]) (eFigure 4 in 