4.3. Study Limitations
This study does have some limitations. First, sEMG assesses the final peripheral pathway, although we expect sEMG signals to also provide information about motor coordination. A second limitation is the lack of follow-up assessments that did not allow the analysis of the retention of training effects.Finally, the inclusion of distal robotic components should also be addressed to possibly enhance the effect on the co-contraction of wrist muscles and promote a better transfer to ADLs.Aware of the above limitations, future studies with a larger sample size should be performed to corroborate the present findings, including EEG/fMRI evaluations, and to assess long-term training effects.