2.6. Secondary Outcome Variables
Fructose breath
Quality of life and areas of life functioning (symptoms, interpersonal problems, social role functioning) using the Outcome Questionnaire (OQ-45.2) scales in German, applying a cut-off score of >63 for clinically significant compromise [Bristol Stool Scale (BSS). The proportion of patients with normal stool consistency was compared.Fructose breath tests. Hydrogen and methane breath concentrations were measured before, 1 and 2 h following ingestion of 35 g fructose dissolved in 300 mL tap water (Quintron BreathTracker SCFurther detailed measurements of cognitive function, faecal collections for microbiome analysis, blood samples for metabolomics, and barrier permeability tests were accrued and will be reported in further publications.