Statistical analysis
A two-way repeated ANOVA was used to analyze the hourly glucose data and VAS, and Dunnett's test was used for multiple comparisons. A one-way repeated ANOVA was used for the analysis of the maximal glucose, AUC, and total AUC, and Dunnett’s test was used for multiple comparisons. The correlation used Spearman’s rank correlation coefficient. The amplitude range of glucose and spent time for glucose were determined by Friedman ranking, and the Dunn method was used for multiple comparisons. We used G*Power to determine the sample size. GraphPad Prism 8.4.3 was used as the statistical software for analysis, and the level of statistical significance was set at 