CONCLUSION
In conclusion, these observations support the myotrophic role of carnitine which is most likely due to the IGF‐1 signaling pathway on muscle protein synthesis and prevents apoptosis. Myogenin is a good marker for muscle growth but it needs a muscle biopsy to reveal the exact result. Moreover, the result of this study supports the inhibitory effect of LC on myostatin. Therefore, LC supplementation increases the serum IGF‐1 and changes the myostatin, myogenin level, and CK activity. However, the mechanism for this effect of LC is not completely elucidated, IGF‐1 is one of the molecules which mediates the LC impact on myostatin and myogenin.