Baseline data and numbers analysed
GROUP B
The final sample included 32 patients (13 women and 19 men), with a mean age of 54.6 years (SD: 10.7; range: 24–72). The general patient characteristics are shown in Table General characteristics of the included sample. No statistically significant differences were found between the groupsThe main results, as well as the scores recorded after the 1-month washout, were as follows: in Group A, the modified XQ score was 70.1 (SD: 25.7; range: 15.4–100) at baseline and 63.2 (SD: 24.3; range: 15.4–96.8) after the washout phase; for Group B patients, the modified XQ score was 58 (SD: 21.2; range:20.9–81.4) at baseline and 59.9 (SD: 21; range: 16.5–90.2) after the washout phase.No statistically significant difference was found between any of the analysed variables (total and divided according to the different categories) or between the groups at different time points. Consequently, the baseline scores were grouped together with the scores after the washout phase, and then the statistical analyses were stratified according to the administered product.To establish the reliability of patients’ answers to the questionnaires, an ICC analysis was performed between baseline questionnaires (before the beginning of Phase 1) and the questionnaires at the beginning of Phase 2, matching the answers for each patient to the same questions: ICC measured at baseline was 0.834, while that measured after the washout period was 0.866.