Author contributions
KS: Data curation, Software, Writing—original draft, Writing—review and editing. YG: Formal Analysis, Methodology, Supervision, Writing—original draft, Writing—review and editing. HW: Data curation, Software, Validation, Writing—review and editing. XH: Conceptualization, Methodology, Validation, Writing—original draft, Writing—review and editing.We gratefully acknowledge the following consortiums: MiBioGen, the MRC Integrative Epidemiology Unit for making their GWAS summary-level statistics publicly available.