FMT restored the Bacterial Community Network in FMT-responders of patients with PD
To determine whether potential changes occurring among bacteria within the gut microbial communities were associated with the different clinical outcomes in FMT.R and FMT.NR subgroups, we constructed two models to investigate the microecological system in the two subgroups. We first constructed 3 time-series molecular ecological networks (MENs) based on the Pearson correlations of log-transformed ASV abundances. As shown in The microbial network analysis in participants after FMT. a: visualization of constructed MENs in FMT.R and FMT.NR subgroups at different times. 18 large modules are shown in different colors, and smaller modules are shown in gray. b-e: comparison of the genera co-occurrence networks between different subgroups. Network plots describing the co-occurrence of bacterial genera in the gut microbiota of donor (b), F.0W (c), F.12W.NR (d), F.12W.R (e) based on the Spearman correlation algorithms (