Conclusions
septic shock
ADVERSE EFFECTS, SEPTIC SHOCK
In conclusion, early adjunctive MB administration reduced vasopressor duration, cumulative fluid balance, and ICU and hospital length of stay among patients with septic shock, as compared with placebo. There were no severe adverse effects related to its use. Our results support the continuous research of MB as an early adjunctive therapy in patients with septic shock to confirm the potential benefit in larger multicenter randomized clinical trials.