Contributors
SW, EH, JH, and JK designed the study. SW, ECM, SMA, and JK planned the study. SW, ECM, and SMA implemented the study. SW, ECM, JH, and JK analysed and interpreted the trial data. SW and ECM wrote the first draft of the manuscript. JH, JK, ECM, and EH revised the manuscript. All authors read and approved the final version of the manuscript, had full access to all the data in the study, and had final responsibility for the decision to submit for publication. SW, ECM, and JH accessed and verified the data. SW and ECM contributed equally to this work.