Clinical, anthropometric and laboratory evaluations
obesity, diabetes
OBESITY, BLOOD, CREST, DIABETES
During the clinical examination, a standardized questionnaire was administered to collect personal information on current health, food habits, physical activity, current and previous treatments, comorbidities, and family history of obesity, diabetes and SAH.AC was measured with a tape positioned horizontally halfway between the iliac crest and the last rib. Height was measured using a digital stadiometer (HM-210 D, OttoboniArterial pressure was measured with a previously calibrated sphygmomanometer, using a cuff compatible with the patient’s arm circumference (cuff size 12 × 23 for 25–34 cm; cuff size 16 × 32 for 35–45 cm). After resting for at least 5 min in a quiet room, arterial pressure was measured twice at a minimum interval of 2 min, as proposed by the 2018 ESH/ESC guidelines for the management of SAHBody weight, segmental fat mass and segmental lean mass were quantified for all body segments (arms, legs, trunk) using an InBody 270 tetrapolar bioimpedance deviceThe bioimpedance device features 8 contact points capable of collecting 10 measurements from each body segment (right arm, left arm, right leg, left leg, trunk) using 2 different frequencies (20 kHz and 100 kHz) and a current of 250 µA (Table Bioimpedance parameters registered in the study.Blood was collected after 12 h of fasting and 72 h of abstention from alcohol and heavy exercise. The lab parameters included fasting glycemia, insulin, glycated hemoglobin, HOMA-IR, total cholesterol, HDL, LDL, triglycerides, uric acid, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR).ESR (mm/hr) was measured in whole blood using the automated Westergreen method. CRP (mg/dL) was measured in serum on nephelometry (Dade-Behring