Introduction
multimorbidity
Inappropriate polypharmacy in older adults is a major driver of healthcare related harm.Medication review interventions, such as those based on the Screening Tool of Older Persons potentially inappropriate Prescription (STOPP) and Screening Tool to Alert doctors to the Right Treatment (START) criteria—evidence based criteria to inform prescribing in older adultsThe Optimising PharmacoTherapy In the multimorbid elderly in primary CAre (OPTICA) trial tested the hypothesis that, in older adults with multimorbidity and polypharmacy, the use of an eCDSS for optimising drug therapy by general practitioners improves appropriateness of medication and reduces prescribing omissions compared with standard care.