3.1. HDL Lipidome
overweight
Analysis of human HDL lipidomic profiles using UPLC-ESI-MS/MS led to the detection of 263 molecular lipid species (The identified GPL species belonged to the subclasses of phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylinositol (PI). Within the group of PCs are included diacylglycerophosphocholine (DAPC) and 1-ether, 2-acylglycerophosphocholine (MEMAPC), while the PE group includes diacylglycerophosphoethanolamine (DAPE) and 1-ether, 2-acylglycerophosphoethanolamine (MEMAPE) metabolites. The PIs were represented by the diacylglycerophosphoinositol subclass (DAPI). As shown in For the second-most abundant lipid class (GLP), triacylglycerols were by far the most numerous lipids (78 compounds); nevertheless, several monoacylglycerols (MAGs) and diacylglycerols (DAGs) were also identified. As shown in The influence of sex on HDL lipid composition, at baseline, in healthy overweight subjects is shown in 