Ethics approval and consent to participate
Ethics approval has been provided by the ethics committee of First Affiliated Hospital of Chongqing Medical University, Chongqing, China (approval number: 2015ZY102, approval date:26/07/2021). Letters of informed consent signed by patients were obtained. This study was conducted in accordance with the principles of the Declaration of Helsinki. The trial was registered at the Chinese Clinical Trial Registry (registration number: ChiCTR2100052214, registration date: 22/10/2021).