Statistical design and analysis
death
REGRESSION, EVENT
The Kaplan-Meier method was used for survival analyses. PFS time was measured from the respective landmark to relapse or death from any cause, whichever occurred first. OS was defined as time from the respective landmark until death from any cause. For analyses of sustained MS from start of maintenance/observation until one year, PFS and OS were calculated from the second time point (after one year) and only patients who did not have a prior progression event were included. MS test results were evaluated in a multivariable Cox regression model including established risk factors. Main analyses were undertaken using R (v4.0.4) software.