Background
forgetfulness, dementia
Recently, population aging has progressed worldwide. The number of people aged ≥ 60 years is expected to increase by 2 billion till 2050 [Exercise habituation, smoking cessation, nutritional intervention, and social activity are recommended to reduce the risk of developing dementia [PC, one of the choline compound in the egg yolk, is the popular source of choline, a precursor to the neurotransmitter acetylcholine, which is hypothesized to help maintain cognitive function [The choline compounds in egg yolk are composed primarily PC, and its metabolites, LPC and α-GPC . They are collectively called egg yolk choline. Although there are various chemical forms of choline, we focused on egg yolk choline because of the high proportion of PC, the phospholipid form in foods.Therefore, a 12-week, randomized, double-blind, placebo-controlled, parallel-group study was conducted to investigate the effect of continuous intake of egg yolk choline on cognitive function. Subjects were healthy, middle-aged, and elderly Japanese males and females aged 60 to 80 years without dementia who were concerned or had been pointed out by others about their forgetfulness.