Recruitment Capacity
WEST
A total of 1 404 771 patients were eligible for electronic screening—14 743 were determined as eligible by study nurses and provided verbal informed consent with 13 523 (91.7%) consented completing randomization (mean [SD] age, 72 [5.4] years; 13 092 male [96.8%]). Of the 4128 consented PCCs, 2944 (71.3%) agreed to the randomization of at least 1 patient.Patients across the US (including Puerto Rico and District of Columbia) were enrolled, demonstrating excellent geographic reach (Although centralized monitoring and research staff were based in Boston, participants of each region of the US were well represented. Among those residing in urban areas (7371 participants), the highest percentages were observed in the South (2892 [39%]), followed by the Midwest (2224 [30%]), West (1114 [15%]), and Northeast (954 [13%]) regions, with the remaining 187 (3%) from Puerto Rico and the District of Columbia. Those residing in rural or highly rural areas (6126 participants) were primarily from the South (2338 [38%]), Midwest (2340 [38%]), West (809 [13%]), and Northeast (631 [10%]) regions, as well as Puerto Rico and the District of Columbia (8 [0.1%]).