Study population
retinopathy, allergic, keratopathy, upper respiratory tract infection, strabismus, glaucoma
RETINOPATHY, UPPER RESPIRATORY TRACT INFECTIONS, KERATOPATHY, STRABISMUS, NEUROMUSCULAR DISEASE, GLAUCOMA, EYE
The institutional review board of Tianjin Eye Hospital approved this prospective, randomized, double-blind study, registered in the Chinese Clinical Trial Registry on 09/12/2022 (ChiCTR2200066586). Guardians of all participants signed informed consent after obtaining a detailed understanding of the study objectives, procedures, and potential risks.A total of 181 children with strabismus undergoing monocular surgery under general anesthesia were recruited at our hospital from December 2022 to February 2023. The inclusion criteria were as follows: (1) aged 7 to 12 years; (2) grade I or II in the American Society of Anesthesiologists (ASA) physical status classification. Patients were excluded if they (1) had a history of glaucoma, keratopathy, retinopathy, neuromuscular disease, difficult airway, or upper respiratory tract infection within 2 weeks before surgery; (2) were allergic to related general anesthesia or local anesthesia drugs, or had received medication affecting IOP within 2 days before surgery; (3) were unable to cooperate with IOP measurement under topical anesthesia before the induction of general anesthesia. More details are provided in Fig. 