Study Population
Respiratory disease, Coronary artery disease, thyroid diseases, LSPAF, Chronic kidney disease, stenosis
CHRONIC AIRWAYS DISEASE, DISEASE, PERSISTENT ATRIAL FIBRILLATION, RESPIRATORY DISEASE, THYROID DISEASES, CHRONIC KIDNEY DISEASE, STENOSIS
Patients with LSPAF enrolled into the CASA-AF randomized-controlled trial (Catheter Ablation vs. Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation) who underwent catheter or surgical ablation were followed up for 12 months. The protocol of the CASA-AF trial and the primary outcome analysis were published previously.As part of the study protocol, echocardiographic measurements of the LA parameters were performed at baseline, 3 months, and 12 months after ablation. Only patients in SR during the echocardiographic examination at follow-up were included in the study to allow all aspects of LA function, including contractile, to be evaluated.Patients with thyroid diseases were defined as those with metabolically active disease requiring treatment. Chronic kidney disease was based on an eGFR <60 mL/minute. Coronary artery disease was defined as previous revascularization or coronary angiography showing >70% stenosis in a major epicardial coronary artery. Respiratory disease was defined as chronic airways disease on regular treatment. A positive history of alcohol consumption was defined as >2 units of alcohol consumption per week.