Author contributions
S.B. and M.R. made substantial contributions to the design and conception of the work and drafted the work. H.T., I.D. and P.L. made substantial contributions to the design of the work and revised it critically for important intellectual content. M.U., K-P.R., S.R. and K-P.K. performed analysis as well as interpretation of data for the work and revised the work critically for important intellectual content.T.K., C.B. and K.F. acquired the data and revised the work critically for important intellectual content. All authors reviewed the manuscirpt.