Completion and distribution
anxiety, intra-abdominal tumors, Nausea
DISEASE
One patient was excluded from analysis due to incongruous baseline dates. For the DTSS, a high completion rate was observed at baseline weekly period (i.e., 68.8% from day 1 to 93.6% to day 7). Completion rates dropped in later cycles, although with most days remaining above 65%. For the DTIS, a high completion rate was observed at baseline (92.9%) and at later cycles (65.4% at cycle 4, 67.0% at cycle 7).Patients showed low symptomatology at baseline with mostly ceiling effects (≥ 20% patients reported the “best” possible score 0 = None, i.e., could not improve) and a good distribution of remaining response options in all DTSS items. Items referring specifically to intra-abdominal symptoms were only answered by a subset, i.e., those with intra-abdominal tumors. These items had the highest percentage of ceiling effects (e.g., ~ 70% of patients reported “None” for item 10: “Nausea”) (Fig. DTSS item distribution at baseline: day -1Patients reported low impact of disease on functioning and daily living at baseline, as most DTIS items exhibited floor effects (> 20% reported no impact of the symptom). An exception to this was observed for the mobility items (i.e., item 1: difficulty moving, and item 4: comfortable in bed), as less than 20% reported no impact. Items reflecting mental concerns (e.g., item 12: fear tests, item 13: fear of recurrence/growth, item 16: anxiety, and item 17: frustration) reported high percentages (≥ 20%) of the worst impact option (Fig. DTIS Item distribution at baseline: day-1