DISCUSSION
In this study, we first implemented fMRI with simultaneous EAS at scalp acupoints GV24 and ST8 using a specially designed HFC12 and electroacupuncture stimulator compatible with an MR scanner. The immediate changes in brain FC during stimulation at acupoints GV24 and ST8 were elucidated through these devices. Prior safety tests showed that the device we used did not interfere with magnetic field uniformity, and the increased temperature near the acupuncture point was not significant. The specific effects of EAS at acupoints GV24 and ST8 were verified by assessing the differences between the after‐stimulation sessions and pre‐stimulation sessions within the EAS group and sham acupuncture group. Therefore, the brain response areas discussed here were presumed to be “EAS‐specific effects only,” which removed the psychological components of needling. Our findings showed that EAS at acupoints GV24 and ST8 produced widespread changes in the right and left ECNs, DMN, AN, and SMN. The main effects were increased FC of the LECN and SMN and decreased FC of the DMN.