2.1. Study Design
This double-blind, randomized, sham-controlled clinical trial was performed between November 2017 and January 2019 at the Laboratory of Applied Neuroscience (LANA), Universidade Federal de Pernambuco, Brazil.All participants signed an informed consent form after being informed of the study objectives and procedures, which was performed in accordance with the Declaration of Helsinki. This study was approved by the local research ethics committee and was registered at 