No treatment effect
Here we summarise the scenarios with no treatment effect in the trial, to check the Type I error rates of our analysis models before going on to estimate their power.For a 5-year trial estimated treatment effects are close to zero (Table A6.1.1, Figure A6.1.1; Type I errors for trials with no treatment effect and smaller residual error variance. Left-hand panel: 5-year trial. Right-hand panel: 3-year trial. Ranges plotted are For a 3-year trial, the mean treatment effects are still close to zero (Table A6.1.3, Figure A6.1.3; The incorrect Type I errors for these mean trajectories reflect the large amounts of non-linearity added, especially when only looking at 3 years of follow-up (see Fig. 