Patients
cancers, tumor
CANCERS, PANCREATIC ADENOCARCINOMA, APC, TUMOR
We retrospectively analyzed CT images of APC patients treated at Changzhou Second People’s Hospital Affiliated to Nanjing Medical University, between September 2016 and June 2019. They were randomly divided into a training cohort with 59 patients and a validation cohort with 25 patients. The inclusion criteria were as follows: (1) newly diagnosed and pathologically confirmed pancreatic adenocarcinoma; (2) absence of concurrent cancers at other sites; (3) TNM stage III or IV according to the 8th edition of the TNM staging system; (4) no prior history of radiotherapy, chemotherapy, or other treatments; (5) complete CT imaging data before chemotherapy and after two cycles of chemotherapy; (6) complete baseline clinicopathological features, including the patients’ age, sex, chemotherapy regimen, treatment effect ,tumor location, ECOG PS, TNM stage, CA19-9. The exclusion criteria were as follows: (1) failure to complete the prescribed chemotherapy regimen as scheduled; (2) incomplete clinical data at baseline; (3) poor image quality. Demographic and clinicopathologic features were collected from the electronic medical records. Informed consent was obtained from each patient, and ethical approval was accepted by the Ethics committees of Changzhou Second People’s Hospital Affiliated to Nanjing Medical University.