Study population
BRAIN METASTASIS, HEART FAILURE
Between June 12, 2019 and June 18, 2021, a total of 79 patients were enrolled and received the study treatment. However, two patients were found to have major protocol deviations (one with brain metastasis and the other with heart failure). As a result, 79 patients were included in the intention-to-treat (ITT) population, while 77 patients were included in the per-protocol (PP) population. As of the data cutoff date on October 31, 2022, 27 patients were still receiving treatment (Fig. 