Author contributions
CB had the idea for this paper. CB and HH performed the statistical analyses. CB wrote and revised the manuscript. All other authors (D-BG, CA, SM, BB-W, JL, GH, KW, CH, MS, H-GP) have contributed substantially to the design, acquisition, analysis and interpretation of study data from the PreFord study and gave their intellectual input to the present manuscript. All authors contributed to the article and approved the submitted version.