Authors’ contributions
Z.L. performed most of the experiments and drafted the manuscript. J.Z., X.Y., and W.L. collected clinical human samples and generated some of the data. Y.L. performed and supervised 4SCAR-T cell manufacturing. C.C. performed IHC staining. C.Z., T.C., and K.C. and provided the administrative and technical support. C.Z., K.C., L.C., and D.W. proofread the manuscript. L.C., D.W., and J.M. wrote the manuscript and contributed to the conceptual advice and supervision of the work. The author(s) read and approved the final manuscript.