3.4. Individual Responses to Interventions Improving Glycemic Control and Baseline Prediction 
T2DM
There was high inter-individual variability in multiple glycemic parameters in response to the interventions, which might have contributed to the lack of benefit of the VD and EX interventions and their combination on glycemic control, i.e., HOMA-IR in participants with T2DM (We conducted comprehensive machine learning analyses to identify baseline lipids that were associated with responsiveness and verified the model performance (Plasma lipidome responding to interventions at three sampling time points. (Alterations in plasma lipidome with interventions at three sampling time points. (Responders and non-responders to interventions and baseline prediction for HOMA-IR. (