5. Conclusions
overweight, vascular and cognitive functions, weight loss
This pilot RCT showed that the supplementation of dietary nitrate alongside a calorically restricted diet could be a promising strategy to improve vascular and cognitive functions in older overweight subjects. Dietary nitrate does not appear to amplify the drop in energy metabolism occurring with weight loss. Further investigations in studies with more robust designs and larger study populations are warranted to substantiate these promising initial findings.