Institutional Review Board Statement
The studies were conducted according to the guidelines of the Declaration of Helsinki and approved by the Institutional Review Board as follows: Study EP-24332T-A013: Lithuanian Bioethics Committee: 2004-03-31 No. 30/2. Study EP-24332T-A014: Lithuanian Bioethics Committee: 2004-09-01 No. 46/1. Study ARD-0301-003: Lithuanian Bioethics Committee: 2005-07-013 No. 47. Study ARD-0301-008: Lithuanian Bioethics Committee: 2006-01-26 No. 4. Study ARD-0301-010: Lithuanian Bioethics Committee: 2007-02-21 No. 10 and IEC for investigation of drugs and pharmaceutical products (Republic of Latvia): 190916-120.