Data availability
De-identified and processed participant data will be shared beginning 3 months and ending 5 years following publication by requesting the corresponding author (Hongbo Wei, E-mail: weihb@mail.sysu.edu.cn) for academic purposes. The corresponding author will reply to the request within 2 months, subject to the approval of the ethics committees of the Third Affiliated Hospital, Sun Yat-Sen University. Source data underlying Figs. 