Using continuous scales
We primarily investigated MRI heterogeneity in our cohort by quantifying the dimensions of The BV/CSF index was calculated by dividing the total volume of the brain (BV) by the total volume of the cerebrospinal fluid (CSF) as described in a previous study [The hippocampus-to-cortex ratio was calculated by dividing the averaged volume of the left and right hippocampus by the averaged volume of 3 cortical regions [