Questionnaires
fever, pain
The Patient Global Impression scale (PGIs) is the patient-reported outcomes counterpart to the Clinical Global Impressions scale. The PGIs is a 1-item questionnaire that asks the patient to rate the severity of a specific condition. The Patient Global Impression of Change (PGIC) measures the patient’s change in clinical status [The improvement was measured in two ways: first, on days 4 and 8, using the PGIC and PGIS scales. The patient was deemed to have improved when he or she reported feeling significantly and slightly better. No improvement was considered: unchanged, slightly worse, and significantly worse. With the analysis of the patient’s diary, an improvement was deemed to have occurred at a value of 0 Bristol evacuations grade 6 and 7, as well as the absence of pain or fever reported by the patient.