2. Methods
RECRUITMENT, APPENDIX
The protocol is based on the Standard Protocol Items: Recommendations for Interventional Trials which provides a comprehensive framework for conducting interventional studies. (Appendix 1). This study registered in the ClinicalTrial.gov Protocol ID: NCT05836454. The study has been approved by the Easten Mediterranean University Health Sciences Ethics Sub-Board of Research and Publication Ethics Board (ETK00-2022-0045) and will adhere strictly to the principles set forth in the Declaration of Helsinki. Prior to participation, all subjects will receive a comprehensive verbal and written explanation from the researchers about the trial and will be required to provide voluntary written informed consent. Currently, this trial is in the participant recruitment stage.