Study design
We performed our randomized control trials between October 2020 and December 2020 in four university hospitals in Egypt: Alazhar University Hospital in Damita, Alazhar University Hospital in Assuit, El Hussien University Hospital, and Elsayed Galal Maternity University Hospital. The study was registered on Pan African Clinical Trials Registry with this ID (PACTR202009736186159) on 04/09/2020 and was approved by the Quality Education Assurance Unit at the Faculty of Medicine, Alazhar University. All the participants agreed to join the study and signed informed consent before beginning. All methods were performed in accordance with the Declaration of Helsinki.