2.3.3. Assessment of individual patient treatment benefits: achievement of an exploratory composite endpoint, CDC
REMISSION, RECTAL BLEEDING
The proportion of patients who achieved CDC, comprising four established treatment outcomes, was assessed at weeks 10 and 58. Patients were considered to have achieved CDC if they achieved: (1) partial Mayo Clinic Score [pMCS] remission [pMCS ≤2 and no individual rectal bleeding, stool frequency or physician’s global assessment subscore >1]; (2) endoscopic improvement [Mayo endoscopic subscore of 0 or 1]; (3) inflammatory biomarker remission [faecal calprotectin <150 µg/g]