Vitamin D and serum lipids
cardiovascular and metabolic conditionsIn
VITAMIN D DEFICIENCY
Various observational studies across the world indicate an association between vitamin D deficiency and low levels of high-density lipoproteins (HDL) and high triacylglycerols, as well as higher levels of apolipoprotein EOne of the strengths of our study was the quantification of the concentration of vitamin D in the blood, which made it possible to follow the intra-person variation in its metabolism. In addition, the analytical reliability of 25(OH)D in the quantification was monitored through DEQAS (the vitamin D External Quality Assessment Scheme), since the laboratory where the quantification was carried out could do it.Regarding limitations, we did not include a placebo group for ethical reasons. A smaller vitamin D dose of 200 IU/d was included to provide an adequate dose-response comparison with the higher dose. Another limitation is that being a pilot study the sample size was not optimal, and there was no evidence of significance in our findings on total cholesterol, HDL-cholesterol and triacylglycerols.Despite the lack of solid conclusions about the clinical benefits of vitamin D supplementation in published studies, achieving vitamin D sufficiency remains crucial in patients with cardiovascular and metabolic conditionsIn conclusion, we found that two different doses of vitamin D supplementation, 200 IU 