Introduction
tumor, postoperative pulmonary complications, thymomas, myasthenia gravis, chronic obstructive pulmonary disease, skeletal, swallowing, vocal and eyelid muscles, lung cancer, weakness, thymic hyperplasia, respiratory muscle, autoimmune disease
TUMOR, THYMOMAS, MYASTHENIA GRAVIS, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, LUNG CANCER, PATHOGENESIS, AUTOIMMUNE DISEASE
Myasthenia gravis (MG) is a specific autoimmune disease affecting the muscles. MG is characterized by varying degrees of weakness in the respiratory, limb skeletal, swallowing, vocal and eyelid muscles. Its pathogenesis is closely related to pathological changes in thymus tissue, including thymic hyperplasia or thymic tumor, with 60–75% of MG patients having thymic hyperplasia and 20–25% having thymomas [Evidently, there were current studies performing aerobic exercise in patients with myasthenia gravis. It indicated that MG patients can improve their muscular functions by incorporating aerobic and resistance strength training, especially in proximal leg muscles, and physical exercise in myasthenia gravis seemed safe and improved neuromuscular parameters and physical performance-based measures [More, early postoperative pulmonary rehabilitation training has been reported to promote the recovery of respiratory function in patients with chronic obstructive pulmonary disease and elderly patients with lung cancer [Preoperative inspiratory muscle training has also been reported to reduce postoperative pulmonary complications in patients undergoing lung, cardiac and major abdominal surgery [Therefore, the present study evaluated the effects of preoperative moderate-intense RMT and aerobic exercise, in addition to chest physiotherapy, on respiratory vital capacity, exercise capacity, and duration of hospital stay in patients with MG, in order to clarify preoperative respiratory muscle training combined with aerobic exercise improves vital capacity and daily life activity following surgical treatment for MG patients.