INTRODUCTION
cerebrovascular disorder, Moyamoya disease, stenosis, MMD
CEREBROVASCULAR DISORDER, MOYAMOYA DISEASE, STENOSIS
Moyamoya disease (MMD) was a rare cerebrovascular disorder characterized by progressive stenosis or occlusion of the internal carotid arteries, leading to the formation of abnormal collateral vessels at the base of the brain.Metabolomics provided a comprehensive understanding of the metabolic state of organisms.Therefore, we analyzed the levels of Met cycle‐related metabolites in MMD and constructed a Met cycle‐related risk model, which helped to demonstrate the correlation between Met cycle and the risk of MMD. Our study suggested that interventions targeting the Met cycle might have therapeutic potential in the prevention and treatment of MMD.