5. Conclusions
EVENTS, PHYSIOLOGICAL STRESS
Four weeks of CIT+GSH supplementation improves brachial artery FMD in apparently healthy postmenopausal women with slightly elevated FBG. CIT+GSH reduced brachial PWV and attenuates BP responses to sympathetic activation. These beneficial effects on the endothelial function and BP reactivity may be attributed to an increased ARG/ADMA ratio. Therefore, CIT+GSH supplementation may reduce the risk of cardiovascular events during physiological stress in postmenopausal women. Although CIT supplementation alone caused greater increases in the serum ARG levels and ARG/ADMA ratio, it did not improve FMD or BP responses to CPT in healthy postmenopausal women.