CD4+ T-cell subsets
In contrast, when we looked at the proportion of CD4+ T-cell subsets, significant differences in trends by arm were detected for both TM and EMRA (arm–time interaction p-value = 0.02 in the adjusted analysis). The significance was likely to be driven by the trends at T6, the time at which values of both TM (−4.6 cells/mmCD4 subsets by study arm—adjusted analysis.RCT, randomized clinical trial; VL, viral load.

Box plots of CD4 and CD8 count subsets and adjusted prediction with 95% CI from fitting the mixed-linear model.