Results
HFpEF
HEART
Between 11 February 2021 and 17 November 2022, we randomly assigned 310 patients to natriuresis-guided therapy (Patient flow diagram. Created with BioRender.com.Baseline clinical characteristicsACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNI, angiotensin receptor neprilysin inhibitor; BMI, body mass index; CRT, cardiac resynchronization therapy; HFpEF, HF with preserved ejection fraction; ICD, implantable cardiac defibrillator; MRA, mineralocorticoid receptor antagonist; NYHA class, New York Heart Association Class.