Outcomes
The primary outcome of this study was incident frailty over the duration of the trial. Secondarily, we assessed change in mean frailty score over time and change in self‐reported functional ability using the EQ‐5D questions for mobility, self‐care, and usual activities. In an exploratory analysis, we examined change in function according to baseline frailty level as prior trials have shown difference in physical function according to frailty level at enrollment (Butt, Dewan, Merkely, et al., 