Effect of UP165 supplementation on sleep quality improvement as it was measured by PSQI
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The PSQI is a self-rated questionnaire that assesses sleep quality and disturbances over a 4-week time interval. Participants who were supplemented with UP165 showed a statistically significant improvement in self-rated questionnaires, indicating the effect of UP165 in enhancing sleep quality and efficiency in healthy participants. UP165 supplementation produced significantly improved sleep quality as early as week 1 (PSQI global scores for three supplement groups. The study enrolled 45 volunteers to participate in a 6-week trial. Participants (age range 19–73) consumed the supplement or placebo ∼60 minutes before bedtime daily for 4 weeks after a 2-week baseline period (no supplementation). The active test material UP165 was administered orally at 250 and 500 mg/day. Data represented as mean ± SE. *Effect of UP165 Supplementation on Sleep Quality Improvement as Measured by Pittsburgh Sleep Quality IndexThe study enrolled 45 volunteers to participate in a 6-week trial. Participants (age range 19–73) consumed the supplement or placebo ∼60 minutes before bedtime daily for 4 weeks after a 2-week baseline period (no supplementation).ANOVA, analysis of variance; PSQI, Pittsburgh Sleep Quality Index.The placebo effect (31.6% increase in PSQI from baseline) observed in week 1 for the placebo group was nonexistent for the remainder of the study period (