Limitations
SECONDARY
Besides some strength of the study as the applied statistical model which has several benefits over traditional analysis methods for longitudinal data and has been proven to have a higher level of statistical power [Second, there were some technical issues at the beginning of the study. During the first weeks, there were some difficulties in accessing the program’s content. The participants were immediately informed about this. However, it cannot be ruled out that these technical problems impacted the perceived user experience of the program.Third, outcomes were only assessed through self-report, which may lead to potential sampling bias [Fourth, secondary outcome analyses were explorative and might be underpowered. They should be interpreted with caution.Fifth, extensive research and considerations were made for the definition of the non-inferiority margin. Nevertheless, some uncertainty remains, as there are no generally valid figures for a clinically relevant effect in this target group to date.