Mechanism of action
inflammation, allergic, infections
INFLAMMATION, TUMOUR NECROSIS, INFECTIONS
The human host, and not the microbe, is the therapeutic focus in Ayurveda while treating infections. The primary objective is to strengthen immunity. Ayurvedic physicians use a holistic approach to treat and heal which includes assessment of the individual constitution (called Prakruti and Doshas in Ayurveda) and several lifestyle changes [Several experimental studies (animal, cell culture, and in-vitro model) of individual plant extract ingredients of AYUSH 64 have provided a wide array of evidence to explain the reduction in inflammation and modulation of immune response (anti-oxidant effect, increased phagocytosis and altered inflammatory pathways- Nuclear Factor Kappa B, p 65), direct inhibition of pro-inflammatory biochemical mediators and cytokines (prostaglandins, tumour necrosis factor alfa, Interleukin (IL)-1 beta, IL-6, and IL- 8), and suppression of inflammatory and allergic response in airways (cellular and cytokines) [