4.4. There Were No Side Effects from Colostrum Use
bloating, gastrointestinal symptoms, diarrhea, abdominal pain
EVENTS
One of the most important concerns of investigators when introducing a novel medical procedure in children is the potential of triggering unexpected results. In the past, the use of colostrum has been blamed for causing side effects such as gastrointestinal symptoms, including abdominal pain, bloating and diarrhea. The symptoms usually last for the first few days of supplementation and are most probably related to the repair processes in the gut, as such processes naturally involves some acute inflammatory events. Therefore, we urged parents and guardians to pay special attention to any unusual symptoms appearing in their children. Over the entire trial period, none of such effects was reported. In addition, all parents and guardians responded to the question pointing specifically to abdominal symptoms. There was no statistically significant difference between the COL group and the PBO group in this regard (