5. Conclusions
T2D, macrovascular complications
Our findings suggest that the consumption of RV at a dose of 1000 mg/day exerts a more efficient antioxidant effect than a dose of 500 mg/day, which coincides with a statistically significant increase in SIRT1 levels in older adults with T2D. This provides evidence suggesting that the consumption of RV in doses of at least 1000 mg/day for 6 months or more could be an adjunctive treatment that reduces the incidence of micro- and macrovascular complications linked to T2D.