PK
Pharmacokinetic parameters evaluated in Part 1 are shown in Table Predicted concentration‐time profiles for different single doses of AK0529 from Part 1 study.
Abbreviations: AUC, area under the plasma concentration‐time curve; Cmax, maximal concentration; CV, coefficient of variation; tThe 4 mg/kg dose group includes additional data from a single subject treated in a preceding phase 1b study (Study AK0529‐1002).In Part 2, an approximate dose proportionality was observed for mean C