Background
Many prior studies have provided evidence that medication therapy management (MTM) can lead to improved health and economic outcomes [We recently completed the INtervention for Cognitive Reserve Enhancement in delaying the onset of Alzheimer's Symptomatic Expression (INCREASE) study, a randomized controlled trial where we tested an MTM intervention that actively involved the patient, a board-certified geriatric pharmacy specialist (BCGP), and a non-pharmacist clinician [The objectives of the current manuscript are twofold: (1) describe the recommendations made by the study BCGPs using participant-reported medical and medication histories for all INCREASE participants, prior to randomization to either the MTM intervention (specific medication recommendations plus provision of educational materials on inappropriate medication use) or usual care (i.e., only provision of educational materials on inappropriate medication use), and (2) describe final recommendations for patients randomized to the MTM intervention. The second objective describes (a) revisions to the preliminary baseline MTM recommendations over the course of the intervention, and (b) participant response to the MTM recommendations following the intervention.