Objectives {7}
bradycardia, involuntary movements, desaturation, hypotension
EVENT, ADVERSE EVENT
The primary objective is to demonstrate the superiority of intranasal dexmedetomidine compared to oral midazolam as premedication in reducing the occurrence of any event (bradycardia, hypotension, desaturation under 95%, and involuntary movements) requiring temporary or definitive interruption of the examination to allow anesthesiologist intervention in children undergoing MRI under propofol sedation.Secondary objectives include the analysis of the synergistic effect between dexmedetomidine and propofol, which would be reflected by a lower consumption of propofol when these drugs are associated, compared to the association of midazolam and propofol. We will also evaluate the effect of premedication on upper airway patency when positioning the patient on the MRI table (lower jaw fixation to extend the cervical spine, the use of Guedel cannula, laryngeal mask or orotracheal intubation) and the experience of the anesthesiologist in charge of the patient on the occurrence of any adverse event, as described in the primary objective, requiring the interruption of the MRI. In addition, we will evaluate the impact of dexmedetomidine on the post-sedation period, reflected by the patient’s wake-up time and the length of stay in the recovery room. Furthermore, we will assess the acceptability of intranasal premedication using the CHEOPS scale and the quality of MRI images.