Parent preference
Parent preference, particularly treatment preference, is an important factor across paediatric RCTs, not least because of the proxy role that parents often play in making treatment decisions [Treatment preference is a key influence which has been found to lead to declining participation in up to 70% of a variety of 52 trial designs [Post hoc trial surveys suggest that parents with higher socio-economic status, high decisional uncertainty and low levels of trust and altruism were more likely to decline trial participation [