Conclusions
HCC
In this large population-based HCC cohort study, antidepressant use after HCC diagnosis was associated with lower overall and cancer-specific mortality among patients with HCC. Our study provides promising empirical results indicating that antidepressants may have utility as anticancer therapeutics in patients with HCC. However, our findings should be interpreted cautiously because the associations found in this observational study may not indicate causality and may be affected by residual confounding or biases. Definitive evidence would require evaluation in randomized clinical trials.