Introduction
death, Sepsis, inflammation, vascular injury, septic shock, sepsis
INFLAMMATION, SEPSIS, SEPSIS, SEPTIC SHOCK
Sepsis and septic shock remain the leading causes of death in intensive care units worldwide [Signs of impaired tissue perfusion during sepsis persist despite apparent successful restoration of systemic hemodynamics [The most abundant endogenous antioxidant is ascorbate, the reduced form of vitamin C [Previously published studies in animals indicate that supplemental vitamin C attenuates systemic inflammation and vascular injury, reduces glycocalyx shedding [