Limitations
depression
Despite the novelty of the current study, this prospective study is still prone to several limitations. One important limitation is the fact that our results are based on cross-sectional observation, longitudinal data are needed to justify a such conclusion. Second, the current study included patients across a wide age range. While this approach allowed us to observe for a diverse sample of migraineurs regardless of age, it also limited our ability to draw conclusions about age-specific effects and their associated comorbidities. For instance, elderly patients are usually more prone to depression [