Time to consistent remission of major depressive disorder
MDD
REMISSION
Time to consistent remission of MDD (MADRS total score ≤ 12 for two consecutive visits) was significantly shorter in patients treated with ESK + SOC versus PBO + SOC: median time, 23 versus 50 days; adjusted HR (95% CI), 1.50 (1.12, 2.00); Kaplan–Meier curves of (Based on the single criterion of MADRS total score ≤ 12 for two consecutive visits, the cumulative probability of consistent remission was 54.2% in the ESK + SOC group versus 39.8% in the PBO + SOC group by day 25; and 75.0% in the ESK + SOC group versus 55.0% in the PBO + SOC group by day 90 (