Introduction
human illness, death, infectious, A/H1N1
INFLUENZA A, DISEASE, INFLUENZA
Vaccination remains an essential public health strategy for the prevention of influenzaFour types of influenza viruses exist: A, B, C, and D; however, only A and B are responsible for the majority of human illness, with influenza A the major cause of severe disease and death in older adultsGenerally, the overall effectiveness of currently available seasonal influenza vaccines, which utilize egg-, cell-, or recombinant protein-based platformsMessenger RNA (mRNA) technology has recently become a promising alternative to conventional vaccine approaches against infectious diseasesThe investigational mRNA-1010 vaccine is a quadrivalent seasonal influenza vaccine encoding membrane-bound HA surface glycoproteins of four influenza strains (A/H1N1, A/H3N2, B/Victoria, and B/Yamagata) recommended by the WHO for cell- or recombinant vaccines