Descriptive statistics of changes of PFT parameters from baseline to 2 years for single ACS and multiple episodes of ACS.
non-ACS
ACUTE CHEST SYNDROME
ACS, acute chest syndrome; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; FEF25-75%, forced expiratory flow rate at 25–75% flow; TLC, total lung capacity; DLCO adj for Hb, diffusing capacity of the lung for carbon oxide adjusted for hemoglobin; KCO, carbon monoxide transfer coefficientAt baseline, for children with ACS, IL5 (ACS, 0.59 [-0.41, 1.89] vs non-ACS, 0.34 [-0.31, 1.11], p = 0.028) and IL-13 (ACS 1.01 [0.05, 2.03] vs non-ACS: 0.05 [0.05, 1.65], p = 0.024) levels were higher (