Introduction
DSD
An estimated 2.1 million young people aged 15 to 24 years old are living with HIV in Southern and Eastern Africa [Differentiated service delivery (DSD) is a person-centered approach in HIV care that aims to offer services according to the specific needs of key groups of people living with HIV [Several systematic reviews concluded that evidence for interventions to improve engagement in HIV care among adolescents and young adults in low-resource settings is of low quality [Together with PEs, young people living with HIV, youth activists, clinicians, district Ministry of Health authorities, and mobile application developers, the PEBRA (Peer Educator-Based Refill of ART) model was developed. In PEBRA, a PE at the health facility assisted by a dedicated eHealth application, assessed regularly patients’ preferences regarding medication pick-up, short message service (SMS) notifications, and psychosocial support and delivered services accordingly.The PEBRA cluster-randomized trial compared the PEBRA model versus standard clinic care, where no PE-coordinated care was offered, in 3 districts in Lesotho. We hypothesized that PEBRA will have a beneficial effect on viral suppression and other clinical and HIV care-related outcomes.