Outcomes
bleeding, seizures, Postoperative defecation, tenesmus, Postoperative pain, diarrhea, postoperative anal distension, pain, constipation, infection, impaired urination, anal pain, Urination, Postoperative anal distension
ADVERSE REACTIONS, BLEEDING, ADVERSE EVENT, INFECTION, URINATION DISORDER
Main outcome measures: The primary endpoint was the VAS scores and the anal distension scores at 8, 24, 48, and 72 h after operation. Secondary endpoints were urination, time to first defecation after surgery, feeling of tenesmus, use of postoperative analgesic drugs, and other related indexes which were observed after surgery.Postoperative pain: VAS was used to evaluate the pain of surgical incision in patients at 8 h, 24 h, 48 h, and 72 h after the operation.Postoperative anal distension: According to the following criteria, postoperative anal distension was divided into 4 grades, grade I (0 points): no anal distension; grade II (2 points): occasional seizures or mild symptoms; grade III (4 points): frequent, severe symptoms, affecting life, can be relieved after rest and treatment; grade IV (6 points): frequent, affecting daily life, and cannot be relieved even after rest and treatment.Postoperative analgesic drug use: the administration times and additional use of ketorolac tromethamine were recorded for each patient. In addition, every use of opioid (Bucinnazine Hydrochloride Injection) should be recorded.Urination 24 h after operation: The evaluation criteria were as follows: grade I (0 points): urination was unobstructed without urination disorder; grade II (2 points): slightly impaired urination, able to urinate without treatment; grade III (4 points): able to urinate on their own, but with less urine volume, abdominal distension and other related signs and symptoms, requiring conservative treatment; grade IV (6 points): no urine is excreted and catheterization is required.Postoperative defecation: The patient’s first defecation time, daily defecation frequency, and feeling of urgency after surgery were recorded.Adverse events occurred during the experiment, including but not limited to bleeding, infection, needle sickness, and unplanned reoperations which were recorded.One month after the operation, the patients were followed by telephone to self-observe the following indicators: whether there was repeated anal pain; whether there was an anal bulge that was difficult to relieve; whether there was tenesmus; whether there was repeated constipation and diarrhea; and other adverse reactions or discomfort symptoms.