Introduction
CKD, chronic kidney disease, arterial stiffness
DISEASE, ARTERIAL STIFFNESS
Patients with chronic kidney disease (CKD) are at profoundly increased risk for cardiovascular (CV) disease and mortality (Exercise training has been shown to decrease muscle sympathetic nerve activity (MSNA) in other clinical populations characterized by elevated SNS activity (Therefore, we tested the hypothesis that 12 weeks of aerobic exercise training reduces resting SNS activity and improves indices of arterial stiffness (i.e., carotid-femoral pulse wave velocity [PWV] and augmentation index [AIx]) in patients with CKD stages III–IV.