Participants
Coma, fractures, TBI, cord injuries, disorder of consciousness
DISEASE, COMA
Participants in the trial were included as a convenience sample of patients admitted to the Neurointensive Care Unit, The Neuroscience Centre, Rigshospitalet, with a clinical diagnosis of severe TBI, a Glasgow Coma Score (GCS) <11 during wake‐up call, a suspected persistent disorder of consciousness, and at least 24 h of stable intracranial pressure (<20 mmHg). Median duration from injury to randomization was 12 days. As the patients included were temporarily incompetent, inclusion depended on informed consent from the next of kin. Patients were excluded if they had spinal cord injuries or fractures of the lower extremities that prohibited weight bearing.A group of 15 healthy volunteers with no known prior disease were also included (Riberholt, Olsen, Skovgaard, et al., 