Participants’ completion of various study stages.
toxicity, Frailty
TERMINAL ILLNESS, COMPLICATIONS
Green: Completion of study collection at end of the week (Week [number] Day 7)Red: Incompletion of study collection at the end of the week (Week [number] Day 7)The primary reason for attrition was due to clinical deterioration from the underlying life-limiting illnesses and associated complications. No participants withdrew from the study due to unacceptable toxicity or intolerance to study intervention as determined by the participant or site investigator. Participants reported finding trial processes burdensome when feeling clinically unwell from the underlying terminal illness and its complications, contributing to the attrition rate. Frailty and functional decline posed logistical challenges for participants.