Patients
Coma, CRS-R, uncooperative behavior, RTT, vascular disease, arthritis, brain injury, fractures, lower joints
VASCULAR DISEASE, COMA, OSTEOPOROSIS, ARTHRITIS
Inclusion criteria were age 18–80 years, written informed consent of the legal guardian, an acquired brain injury, and a clinical state of UWS or MCS according to repeated Coma Recovery Scale-Revised (CRS-R) assessment [Exclusion criteria were pre-existing DoC, continuous intravenous sedation with propofol or midazolam, body weight above 135 kg (due to technical constraints of the RTT device), length of the legs below 75 cm or above 100 cm (due to technical constraints), fixed contractures of lower joints (hip, knee, foot), instabilities in the bones (fractures, instability in the spine, osteoporosis, arthritis), lesions of the skin on lower extremities, and cardiological contraindications. Further, aggressive, and uncooperative behavior of the patient led to exclusion as well as disproportional growth of lower extremities and/or spine, vascular disease of lower extremities, pacemaker, or pregnancy.