Pharmacokinetics and metabolism
Pharmacokinetic (PK) samples were collected prior to the 1st, 2nd, 4th, and 8th infusions of Cycle 1. In addition, samples were taken at 30 min, 1 h, 1.5 h, 2 h, 3 h, 4 h, 6 h, 24 h, and 48 h after the 1st infusion and at 2 h and 24 h after the 2nd infusion. Maximum concentration (C