COVID-19 convalescent plasma preparation
respiratory tract infection
RESPIRATORY TRACT INFECTION, SARS-COV-2 INFECTION
CCP-specific donors were carefully selected based on specific criteria. Donors were chosen from individuals with a confirmed SARS-CoV-2 infection through PCR testing within the past 28 days. Male donors weighing more than 50 kg were preferred to ensure an adequate volume of plasma (>250 mL) and eliminate the possibility of pregnancy. The selected donors were aged between 18 and 60 years and had recovered from respiratory tract infection symptoms. All eligible donors met the plasma donation criteria. The neutralizing antibody titer was assessed using a micro-neutralization assay conducted at Mahidol University’s Faculty of Sciences. All recruited donors had a neutralizing antibody titer of ≥1:320, exceeding the Food Drug Administration–recommended threshold of ≥1:160 and anti-SARS-CoV-2 ELISA IgG EUROIMMUN ratio 