2.6. Statistical Analysis
All analyzes were performed using R software (R Core Team, 2013). The sample size was calculated to detect a difference in DHI of 5.1 units and a loss of follow-up of 20%. The estimated sample size calculation was 24 for each group. For the comparison of the quantitative variables, we used the t-test, and for the ordinal variables, Mood’s median test. Values < 0.05 were considered statistically significant.