References
SE
Median mtDNA levels (D-loop, ND1, and ND6) with interquartile range, log transformed. (Human mtDNA sequence map. Created with Timeline sample collection in donor and recipient.Baseline characteristics of donors and recipients.Data given as mean (±SD), median (IQR), or Univariable mixed models of plasma mtDNA.Linear mixed models were used to study the dynamics of plasma mtDNA. Variables were tested on the intercept (I) and the slope (S) of the mixed model. Best-fitted models are presented with estimates of fixed effects (b with SE). Statistical significance was set at Univariable testing for the prediction of eGFR and acute rejection episode.Linear mixed models were used to study the dynamics of eGFR. mtDNA variables were tested on the intercept (I) and the slope (S) of the mixed model. Best-fitted models are presented with estimates of fixed effects (b with SE). Statistical significance was set at Multivariable testing for the prediction of eGFR.Linear mixed models were used to study the dynamics of eGFR in a multivariable manner. Donor, recipient, and transplantation-related variables were tested in a univariable manner, from which a crude model was built. mtDNA variables were tested on the intercept (I) and the slope (S) of the crude model. Best-fitted models are presented with estimates of fixed effects (b with SE). Statistical significance was set at 