Primary behavioral outcome
CRS-R
Change in the state of consciousness was defined as the primary outcome. The LoC was assessed by means of the CRS-R scale. The CRS-R [For analysis, the proportion of patients who improved by at least one diagnostic category (according to the CRS-R) was determined, i.e., either from UWS at least to MCS or from MCS to eMCS. The CRS-R modified score was used to determine the LoC in greater detail. To quantify patients’ evolution during the intervention, the difference between the CRS-R assessment at T0 and T3 or T4 was determined by subtracting the CRS-R modified score at T0 from the one at T3 orT4, respectively.