AUTHOR CONTRIBUTIONS
Paul Johan Høl: Collected and interpreted the data, performed the statistical analysis, created the figures, carried out literature search, wrote the article and revised the manuscript.Thomas Kadar: Designed the study, provided clinical review of patients in clinic, wrote the article, carried out literature search.Geir Hallan, Ove Furnes, and Kari Indrekvam: Designed the study, revised the manuscript.Anne Marie Fenstad: Provided patient details from initial study, controlled the statistical analysis and revised the manuscript.