Background
Pulmonary embolism, cardiovascular illness, venous thromboembolism
PULMONARY EMBOLISM, WELLS
Pulmonary embolism (PE) is a common severe cardiovascular illness andcan be life-threatening if left untreated [Commonly used clinical pretest probability, such as Wells score and Geneva score, combines clinical symptoms with predisposing risk factors of venous thromboembolism and classifies patients with suspected PE into distinct risk categories [In this investigation, we aim to develop a comprehensive PE pretest score that incorporates clinical indications in Wells score and other important clinical predictors to guide clinicians in assessing PE risk with improved screening performances. The proposed PE Comprehensive Screening Score (PECSS) is designed to optimize the rule out performance among patients with severe PE and to achieve excellent operating characteristics among patients with moderate and mild PE. PE severity grades were evaluated based on CTPA and validation of PECSS was conducted in an independent held-out data set.