Background
DISEASES, DISORDERS
The continued rise in chronic and mental health conditions, and commensurately in their associated health care costs, is not a new phenomenon. What is new—and reinforced by the COVID-19 pandemic—is the realization of a need for novel approaches to deliver care for these conditions closer to where individuals live and work, such as in their own homes and communities. As health care organizations and providers rush to adapt to this new reality, the adoption of digital technologies has accelerated rapidly [Under the umbrella term digital technologies, it is crucial to distinguish between 3 separate categories, which are sometimes conflated or used interchangeably: Powered by computer software, DTx can deliver evidence-based therapeutic interventions that prevent, manage, or treat a spectrum of medical disorders and diseases directly to patients [Interest in DTx began to surge in 2017 when the US Food and Drug Administration approved the first DTx for the treatment of opioid use disorders [Although considered a rapidly emerging class of medicine, the economic value of DTx is yet to be understood, resulting in an important knowledge gap that limits its widespread uptake [In the context of budgetary constraints and the enduring need for optimal resource allocation in health care, determining the best mix of health services and treatments to maximize clinical outcomes while minimizing costs is critical [