5. Conclusions
HF meal-induced
In this study, the metabolites of two extracts of IC were analyzed and compared. It was found that the content of flavonoids in the ICP was increased and cynaroside and apigenin were the main components. In addition, this is the first study to demonstrate that acute consumption of an HF meal accompanied with IC extract decreases postprandial serum glucose, and IC extracts significantly improve serum antioxidant status responses to the HF meal by increasing serum T-AOC. However, IC could not reduce the effect of HF meal-induced in postprandial TG and TC. The results show an important role played in maintaining glucose metabolism and a certain protective effect on human metabolism after HF diet. IC has potential application value in the pharmaceutical and food industries. Importantly, the study might contribute to the development of functional foods and pave the way for the hypoglycemic drugs of IC as consolidated source of bioactive ingredients.