Authors’ contributions
LVE, NB
RECRUITMENT
JVR, VC, RRA, EG, NB, LVE, MVM, PV: laboratory analysis; MK, FP: (specialized) statistical analysis; JVR, PA, RDL, MAA, CD, BK, KRO, NB, CB, PV: clinical study concept and design. PA, RDL, MAA, CD, BK, KRO, CB: patient recruitment and treatment. All authors: data analysis and interpretation, critical review of the manuscript, approval of the final version of the manuscript. All authors read and approved the final manuscript.