Subject terms
Anorexia nervosa, AN, anorexia nervosa
Anorexia nervosa (AN) is a deadly illness with no proven treatments to reverse core symptoms and no medications approved by the US Food and Drug Administration. Novel treatments are urgently needed to improve clinical outcomes. In this open-label feasibility study, 10 adult female participants (mean body mass index 19.7 kg mPhase 1 trial results demonstrate that psilocybin in conjunction with psychological support is safe, tolerable and deemed acceptable and therapeutically meaningful by female individuals with anorexia nervosa.