Conclusion
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The results from this study implied that the lotion containing VHProbi® Mix R fermented lysate is well tolerated in strengthening skin barrier and may be able to mitigate the severity of sensitive skin after 30 days of intervention. Detailed immunomodulatory studies are needed to determine whether the components of VHProbi® Mix R could influence the pro-inflammatory and anti-inflammatory immune response, thereby affecting the development of sensitive skin. Further randomized, placebo controlled clinical studies are also required to validate the findings here and to better understand the mechanisms of postbiotics in the topical management of common dermatological conditions.