Lumbar spine, femoral neck and whole body BMD
After 1 year, BMD of the lumbar spine did not change significantly in either the MK-7 or placebo groups and the mean changes from baseline or absolute BMD levels did not differ between study groups (Effects of 2-years of supplementation with vitamin K2 (MK-7, 360 μg daily) or placebo: Bone mineral density. Mixed effect model analysis of changes in bone mineral density. (There were no significant differences between the study groups in BMD changes of the femoral neck or whole body (all Adjustment for gender and age and baseline vitamin K and D levels did not significantly modify the results of MK-7 on BMD of the lumbar spine, femoral neck or whole body (Table 3 and Supplementary Table 7S).