Statistical analysis
anaemia, scabies, convulsions, congenital cataract, abscess, skin infection, Overweight WLZ>2, thrush, malnutrition, dermatitis
ANAEMIA, SCABIES, OBESE, ABSCESS, SKIN INFECTION, OTITIS MEDIA, THRUSH, MALNUTRITION, REGRESSION, DERMATITIS
Analyses involved the use of descriptive statistics, as well as univariate regression models. Descriptive statistics involved the use of frequencies and proportions for categorical variables, and mean, median, range, IQR and SD for continuous variables. Sociodemographic and clinical factors associated with neurodevelopmental delay and malnutrition in infants were examined in univariate logistic regression models using the total dataset without age categorisation due to small sample size. Risk of neurodevelopmental delay or malnutrition was computed as an OR with a confidence level of 95%. All analyses were completed using STATA V.13.0 Stata/MP.Child medical experiences were summarised as past medical illnesses (since birth) or current medical status (within 2 weeks of the assessment). MDAT and HINE total and domain scores were calculated. MDAT scores were investigated using two methods. First, the MDAT was noted as failed overall if a child was unable to complete two or more items in any one domain that would be expected to be passed by 90% of the normal reference population at their age.For growth, WHO child growth standards were used in calculation of z-scores as provided in the STATA igrowup package.All available data were included in the analyses. There were few missing datapoints, and any cases of missingness for pregnancy, infant and child health characteristics are noted in Delivery and immediate postnatal period characteristics*Infants >37 weeks’ gestation were included only if birth weight was <2500 g.†Infants 2500–2999 g were included only if gestational age was <37 weeks.Child characteristics at time of visit*Normal (≥−1 for WAZ and LAZ; ≥−1 to ≤2 for WLZ), at risk (≥−2 to <−1), moderate (<−2 to ≥−3), severe (<−3). Overweight WLZ>2 to ≤3, obese WLZ>3.†Composite malnutrition includes infants who were either underweight, stunted or wasted.‡Other illnesses included abscess (1), thrush (4), scabies (8), dermatitis (3), skin infection (18), anaemia (1), convulsions (3), otitis media (1), congenital cataract (1).