Bridging therapies
Bridging therapy was defined as treatment delivered after diagnosis of the most recent relapse prior to initiation of cRIT. Specifically, surgical resection, EBRT (focal and/or CSI), and medical therapy (both systemic and intrathecal chemo- or immunotherapies) at time of most recent relapse prior cRIT were noted. In addition to bridging therapies, treatment details of all EBRT (e.g., receipt of CSI, delivery with protons, dose, and number of treatments) both pre- and post-cRIT were collected.