Statistics
weight gain
We analyzed weight gain and BMI increase occurring both during the first 2 weeks (phase I) and weight gain during the entire 8 weeks. This was due to the design of the study (the ‘switch’ in some patients’ medication after 2 weeks) and, as expected, discontinuations of some individuals. For both time periods, we at first looked at all patients combined and in a second step at individuals that received only either one of the SGAs. In addition, we analyzed a ‘first episode’ subpopulation with Statistical analysis was carried out using IBM SPSS Statistics for Windows, version 21.0 (IBM Corp., Armonk, N.Y., USA). We checked raw data for plausibility, then calculated different variables for further analysis, for example for each individual patient i:
Two-tailed 