CONCLUSION
acute pain, TKA, pain
In conclusion, the functional activities in the right MFG, right SMA, bilateral precuneus, right CAL, and left IFGtriang in patients with acute pain after TKA decreased. EA on four acupoints (Futu, Zusanli, Yinglingquan, and Yanglingquan) can increase the functional activities of right cuneus, right angular gyrus, MOG, left MTG, and precuneus. The functional activity of the precuneus is a biomarker of pain after TKA. Enhancement of functional activity of precuneus may be the neurobiological mechanism of EA in treating acute pain following TKA.