Timeline and disruption due to the coronavirus disease 2019 pandemic
coronavirus disease 2019
RECRUITMENT, CORONAVIRUS DISEASE 2019, RECRUITMENT
Recruitment began on 4 November 2019 and the last participant was enroled on 21 July 2020. Follow up of participants ended 12 months later, as planned. The first confirmed cases of coronavirus disease 2019 (COVID-19) in Tanzania occurred in mid-March 2020 and caused severe disruption [We maintained the schedule of appointments following initial meetings with participants. On 17 April 2020, Amana Hospital, our busiest recruitment site, was closed to non-COVID-19 patients, with a 24 h notice period. Trial participants were transferred to Mwananyamala Hospital, which had not previously been a trial site. On 28 August 2020, Amana Hospital was re-opened to all patients and trial participants were transferred back as this was their local health facility.