Results
exhaled breath
From 1426 returned questionnaires, 768 children had home assessments and 241, including 53 enrolling into the RCT, underwent detailed assessments. EBC was successfully collected and analysed from 218 (91%) children at baseline. 48 of the 53 RCT participants completed treatment and 46/48 (96%) post-treatment EBC samples were successfully collected and analysed. Participant demographics at baseline and for the RCT groups are shown in Table Participant demographics.Preterm born vs Term born: *p < 0.05, **p < 0.01 ***p < 0.001 Chi-squared test/independent samples t-test as appropriate.Treatment groups: *p < 0.05, **p < 0.01 ***p < 0.001 Chi-squared test/ANOVA with Bonferroni correction as appropriate.Comparing EBC volumes within groups pre and post treatment: EBC, exhaled breath condensate; ICS, inhaled corticosteroids; ICS/LABA, inhaled corticosteroids and long-acting beta agonist. No significant differences seen between RCT treatment groups.We identified 210 different proteins as detailed in the online supplementary Table 