Cell treatment for proteomics selectivity experiments
For selectivity analysis, isolated human PBMCs (AllCells) were treated with KT-474 at 300 nM in RPMI 1640 media supplemented with 10% FBS and penicillin–streptomycin for 24 h. Vehicle (DMSO)-treated cells at a final concentration of 0.05% (v/v) were used as controls.