Meaning
SECONDARY
This study supports a standard daily supplemental dose of 400 IU of vitamin D in breastfed infants in Montreal, even if born with serum 25-hydroxyvitamin D concentrations less than 50 nmol/L.This prespecified secondary analysis of a randomized clinical trial evaluates whether a higher dose of supplemental vitamin D (1000 vs 400 IU per day) is required in infants born with 25-hydroxyvitamin D (25[OH]D) concentrations less than 50 nmol/L for bone mineral accretion across infancy.