Study population
hepatitis B, human immunodeficiency virus antibody, or
HEPATITIS B, VIRUS, HEPATITIS C, DISEASES
Healthy men between the ages of 18 and 65 with a body mass index ranging from 18 to 30 kg/mMajor exclusion criteria included testosterone less than 12 nmol/L, a history of using GnRH agonists or GnRH antagonists within 6 months prior to screening, and a history of using any androgen or anti-androgen drugs within 5 half-life periods prior to screening. Other exclusion criteria included levels of glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, or total bilirubin exceeding the upper limit of normal value at screening; chronic or serious diseases that affect drug absorption, distribution, metabolism, and excretion; positivity for hepatitis B virus, hepatitis C virus, human immunodeficiency virus antibody, or 