2.4.2. Exclusion criteria.
gallstones, SARS-CoV-2 infection, kidney disease, liver disease, hepatic or biliary abnormalities, Gilbert syndrome
GALLSTONES, ADVERSE EVENT, SARS-COV-2 INFECTION, KIDNEY DISEASE, LIVER DISEASE, SYSTEMIC INFECTION, GILBERT SYNDROME
Patients will be excluded if they have ≤ 93% (room air) saturation of percutaneous oxygen during wakefulness; require oxygen administration or respirators; are strongly suspected or expected to have worsening of symptoms associated with SARS-CoV-2 infection within 48 hours after randomization in the opinion of the investigator or subinvestigator; have suspected active and systemic infections (excluding SARS-CoV-2 infection) requiring treatment at the time of randomization; currently have or have a chronic history of moderate or severe liver disease or known hepatic or biliary abnormalities (with the exception of Gilbert syndrome or asymptomatic gallstones), or moderate or severe kidney disease (Grade 2 or higher based on Common Terminology Criteria for Adverse Events version 5.0Patients satisfying inclusion criteria 1 to 3 and not satisfying exclusion criteria 1 to 4 listed above are considered to have mild-to-moderate COVID-19.