3.1. Drug Resistance among Children on ART with Virologic Failure
viremia
MINOR, VIREMIA
Among the one hundred and six participants with at least one DRT result, all demonstrated at least one clinically significant mutation or minor DR mutation, as defined by the Stanford HIV Database. A total of 93 (87.7%) had clinically significant mutations, and 13 (12.3%) had minor mutations only (Among the eighty-eight CHIV in the intervention group of the study who had DRT requested, forty-seven (53%) had more than one DRT requested for repeat viremia during the study, whereas no CHIV in the control group had more than one DRT. Only three participants initially had minor resistance and later had clinically significant resistance on repeat DRT. Similarly, only six children went from a single class with resistance to two or more drug classes. No children with a change in resistance on follow-up DRT had ART regimen changes between DRTs.