Statistics
Statistical analyses were performed using IBM SPSS Statistics Version 28.0 (Armonk, New York, USA) and Prism Version 9.4.1 (GraphPad Software, San Diego, CA). Graphs were created with Prism. Normality of the data was tested by Shapiro-Wilk normality test. Statistical significance was calculated using either an unpaired two-tailed Mann-Whitney test for pairwise comparison or an unpaired Kruskal-Wallis-Test with Dunn’s correction for group comparisons, depending on the data sets to be analyzed. The correlation was determined with the Spearman correlation coefficient. Statistical significance was set at 