Ethics approval and consent to participate
ClinicalTrial.gov (NCT 04023786). Registered July 18, 2019. The trial protocol was approved by an independent ethics committee (Comité de Protection des Personnes EST-III, Vandoeuvre-les-Nancy, France) (N° 2018-A01599-46). Written informed consent was obtained from each patient or from the patient’s legally authorized representative if the patient was unable to provide consent. Alternatively, deferred written informed consent was obtained from patients. The current study was performed in accordance with French law and the Declaration of Helsinki.