Results
POCD, Thalamus
REGRESSION
In total, 301 patients underwent neuropsychological testing and MRI before surgery. The mean age was 72.4 years (SD 4.9) and 131 (43.5%) were female (Table Of the 301 patients, 34 (11.3%) had preCI. Patients with preCI had a mean age of 73.7 years (SD 4.4) and 17 (50%) were female. Of the 34 patients who had preCI, 7 (20.6%) developed POD and 20 (58.8%) participated in the follow-up cognitive testing. We observed an OR of 0.79 ([95% CI 0.61–1.004] p = 0.06) per cmOf the 212 patients that received the postoperative testing at the 3 month follow-up, 25 (11.8%) presented with POCD. Of the 89 patients (29.5%) that were loss-to-follow-up, 19 (6.3%) dropped out of the study, 15 (5.0%) died before the follow-up, 19 (16.3%) were not reachable, and 26 (8.6%) were still alive, but were not tested for different reasons. 10 patients (3.3%) paused their participation. Although they did not want to participate in the 3 month testing, they consented to attending the subsequent follow-up testing. Of the 89 patients that did not receive a cognitive assessment at the 3 months follow-up, 24 (27.0%) developed POD, 5 (5.6%) died during their postoperative stay in the hospital.Of those 25 patients with POCD, one (4%) had preCI prior to, and one (4%) developed POD after surgery. The mean age of patients with POCD was 75.1 years (SD 6.0) with 11 (44.0%) female patients. In a simple logistic regression, thalamic volume was not statistically significantly associated with POCD (OR per cmBoxplots of thalamus volume across groups. Thalamus volume in cm