Study population
cognitive impairment, stroke, fracture, cord injury, sarcopenia, malignancy, communication disorders, lower back pain, hip/knee arthroplasty, claustrophobia
PARKINSONISM, CENTRAL NERVOUS SYSTEM DISORDERS, STROKE, SARCOPENIA, HEARING LOSS, INFLAMMATORY DISEASE
This study was an open-label, single-arm pilot study conducted in a single center. Eligibility criteria included older (≥ 65 y) community-dwelling women diagnosed with spinal sarcopenia in our previous cohort study (SarcoSpine cohort) [
Flow diagram of this studyIndividuals who met the following criteria were excluded from this study: (1) lower back pain with a numeric rating scale score of 5 or more; (2) previous surgical history of the lumbar spine; (3) surgical history of hip fracture or hip/knee arthroplasty; (4) contraindications for MRI (e.g., presence of cardiac pacemaker, implanted metallic objects, and claustrophobia); (5) central nervous system disorders (e.g., stroke, parkinsonism, and spinal cord injury); (6) cognitive impairment (mini-mental state examination score < 24); (7) communication disorders (e.g., severe hearing loss); (8) musculoskeletal conditions affecting physical function (e.g., limb amputation); (9) long-term corticosteroid use due to inflammatory disease; (10) malignancy requiring treatment within the previous 5 years; and 11) other medical conditions requiring active treatment [