Outcomes
death
DISEASE PROGRESSION, SECONDARY, MAY
The primary endpoint was the 6-month PFS rate. PFS was defined as the time from the start of treatment to the first documented sign of disease progression or death from any cause. The reported secondary endpoints included PFS, OS, and safety. Other secondary endpoints, such as time time-to-progression, time to subsequent treatment, time to second treatment, and PFS2 were not reported because a majority of patients were still ongoing at data cutoff. OS was defined as the time from the first treatment to death from any cause. The cutoff date was May 25, 2023. Investigation of biomarkers of response was a pre-specified exploratory outcome.