Protocol
PDR, type 2 diabetes, hyperprolactinemia
HYPERPROLACTINEMIA, TYPE 2 DIABETES
Briefly, from 175 screened PDR mestizo patients with type 2 diabetes undergoing elective primary pars plana vitrectomy, 41 eligible patients signed the informed consent, and their blood was withdrawn to evaluate PRL, HbA1c, and creatinine levels. From these 41 patients, 2 were excluded due to basal hyperprolactinemia (>20 ng/ml) and 3 because of vitrectomy being re-scheduled. All 36 patients (19 females and 17 males) met the inclusion criteria (aged 40–69 years, no history of prior vitrectomy, PRL serum levels ≤20 ng/ml, and glomerular filtration rate >28 ml/min) and were randomized 1:1 to receive placebo (orally TID, 