Invasive fungal disease (IFD) in the different treatment phases (protocol I, II, III and HR cycles, respectively) in standard (SR) and intermedium risk (MR) patients (above) and high risk (HR) patients (below).
proven/probable, IFDs, infections
REGRESSION, INFECTIONS
Shown are the absolute number of possible (blue), probable and proven yeast (orange) and probable/proven mold (grey) infections (Y axis). The percentages refer to the total number of IFDs in the respective risk groups (SR/MR and HR).Logistic regression revealed that the risk for proven/probable IFD was significantly increased in children ≥12 years of age [OR 1.4 (95% CI 1.3; 1.6)] and those with more than 10% blasts in the bone marrow on day 15 assessed by flow-cytometry [OR 2.3 (95% CI 1.7; 3.2)] (