Tumor molecular profiling
cancer, Cancer
CANCER, CANCER
A next-generation sequencing (NGS)-based analysis for the detection of somatic variants of 146 cancer genes, including single-nucleotide variants (SNVs) of 134 genes and copy number gains of 47 genes, was performed on the DNA extracted from the available samples at the MD Anderson Cancer Center Clinical Laboratory Improvement Amendments (CLIA)-certified Molecular Diagnostics Laboratory (MDL). When possible, an in-house NGS-based analysis for the detection of targeted intergenic and intragenic fusions involving 51 cancer genes (RNA) was performed at the MD Anderson Cancer Center MDL. When possible, in-house fluorescence in situ hybridization assay (cytogenetics) was performed for 