Limitations
cardiac arrest
CARDIAC ARREST
This study has limitations. As highlighted above, we cannot determine if high p-tau in patients with cardiac arrest predicts the onset of AD and the dynamic of p-tau less than 24 hours after the insult. Further, our validation cohort did have a high number of missing values for p-tau and Aβ. However, a sensitivity analysis including only complete cases across all biomarker measurements determined that missing data did not affect the interpretation of our findings (eFigure 6 and eTables 5-7 in 