Pathologic Outcomes
carcinoma, Tumor
DISEASE PROGRESSION, TUMOR, CARCINOMA, RESIDUAL CANCER, SENTINEL LYMPH NODE, SENTINEL NODE, EVENTS
All patients underwent definitive surgery within 1 month of the end-of-study drug administration. Four patients underwent mastectomy with either axillary lymph node dissection or sentinel lymph node biopsy, depending on the initial nodal status. Two patients underwent lumpectomies and sentinel lymph node biopsies due to patient preference. Pathologic analysis of the surgical specimens demonstrated that 1 patient had a pCR, with no residual invasive carcinoma and zero of the three sentinel nodes involved with carcinoma. Three patients had residual cancer burden (RCB) class II. One patient had no significant response (RCB class III), and one patient had disease progression at the time of surgery (Tumor sizes, response to therapy, and follow-up events