Interventions
SIDE EFFECTS
ADeSS was a two-arm cluster-randomised study. GP practices were allocated either to the intervention arm (herein ‘Decision tool’) or the control arm (herein ‘treatment-as-usual’; TAU). In the Decision tool arm, patients received treatment from GPs who were using the computerised decision support tool. The tool assisted with antidepressant prescriptions and prompted GPs to review patients’ medications and change them if ineffective. The algorithm and technical requirements of the tool are described in the trial protocol.Patients meeting the above eligibility criteria and consenting to participate in the study attended the participating GP in their practice for treatment over 14 weeks. Patients received the intervention or control based on the arm that their GP practice was allocated to. Side effects were assessed for each week of the treatment period via the mobile app using the FIBSERFor patients who were not able to use the mobile app (eg, incompatible phone or other technical difficulties), weekly FIBSER scores were collected by the study team via telephone/email. Follow-up assessments took place at 15–18 weeks after the baseline interview.