Definition of near-complete response
tumor, fibrosis
TUMOR, RESIDUAL TUMOR, MINOR, FIBROSIS, ULCERATION, PRIMARY TUMOR

Endoscopic: residual tumor size ≤ 2 cm (or reduction of ≥ 70% original tumor volume/size) [Clinical: only superficial ulceration or minor (questionable) irregularities of the mucosal/rectal wall.Radiological: mrTRG2 predominant fibrosis with low signal with foci of intermediate tumor signal intensity seen on T2 weighted images with or without restricted diffusion; mrTRG1: fibrosis with low signal intensity seen on T2 weighted images replacing the primary tumor with restricted diffusion; no nodes with border irregularity or mixed signal intensity; no EMVI [