Statistical analysis
Statistical analysis was performed using SAS version 9.4 (SAS Institute Inc, Cary, North Carolina, USA). Categorical variables were reported as frequency and percentage, continuous variables were reported as means and standard deviations (SD). The One-Way ANOVA or Kruskal-Wallis test was used for comparison of continuous data, and χ2 test /Fisher’s exact test was used for comparison of categorical data. A 2-side p-value of less than 0.05 was considered as statistically significant.