Statistical analysis
REGRESSION
All efficacy analyses were performed in a modified intention‐to‐treat manner, comprising all randomized participants not lost to observation. For the baseline variables, the summary statistics were denoted as frequencies and proportions for categorical data and median (interquartile range) for continuous variables. The estimated change in the MDA‐LDL level, LDL‐C level, and MDA‐LDL/LDL‐C ratio from baseline to 24 months (including 95% confidence intervals) were analyzed using an analysis of covariance. This model assessed the difference in the trends from baseline to each time point; the treatment groups were modified for age, sex, UA concentration, and baseline MDA‐LDL level, LDL‐C level, and MDA‐LDL/LDL‐C ratio. The outcome variable was natural‐logarithm transformed to satisfy the assumption of error term normality. To illustrate the relationships between changes in UA level, MDA‐LDL level, LDL‐C level, or MDA‐LDL/LDL‐C ratio, linear regression analyses, modified for each value at baseline, were conducted. All 