Estimated ETC Association With the Proportion of Home Dialysis Use Using a Controlled Interrupted Time Series Analysis
END-STAGE RENAL DISEASE
Abbreviation: ETC, End-Stage Renal Disease Treatment Choices.Estimates were based on the final model with main effects of time, ETC, and pre-post implementation, and 2-way interactions of time and pre-post implementation and of ETC and pre-post implementation. The 2-way interaction of time and ETC assignment and the 3-way interaction of time, ETC assignment, and pre-post implementation were not statistically significant and thus were removed from the final model.Estimates were based on the initial model including the 3-way interaction of time, ETC assignment, and pre-post implementation and all 2-way interactions (time and ETC, time and pre-post implementation, ETC and pre-post implementation) to examine whether any changes in use trends after ETC onset differed by ETC assignment.After ETC onset, the percentage of patients initiating home dialysis in ETC markets was slightly higher than in non-ETC markets (0.32%; 95% CI, −1.08% to 1.72%). Although this difference between ETC and non-ETC markets was not statistically significant, the difference in the change that occurred after January 2021 was a statistically significant increase in ETC markets after ETC onset compared with non-ETC markets (1.07%; 95% CI, 0.16%-1.97%). In addition, the overall rate of increase in home dialysis use nearly doubled after ETC onset to 1.66% (95% CI, 1.15%-2.18%). There was a nominally higher rate of increase in home dialysis use in ETC markets compared with non-ETC markets after January 2021 (0.85% per year; 95% CI, 0.00%-1.69% per year), but this difference was not statistically significant. The change in the slope from before to after January 2021 also did not differ significantly in ETC compared with non-ETC markets, and this interaction term was removed from the final model.