Data availability
dilated heart failure, hypertensive
MUTANT, SUDDEN DEATH
In accordance with institutional guidelines to ensure access to qualified researchers and applicable laws, regulations and policies governing data sharing and IP, applicable data be made available to collaborating researchers and submitted for peer-reviewed publication as per NIH standards. Genetically modified or mutant organisms were not generated in this project. Instead, non-genetic animal models were generated with varying degrees of risk for spontaneous sudden death that mimic their human counterparts as follows: (a) thickened hypertensive hearts; (b) non-ischemic, dilated heart failure; and (c) controlled surgical and/or pharmacological interventions. Generated resources include animal tissue, proteome/phosphoproteome data and physiological data. For example, Western blot, RT-PCR, immunofluorescence, histology, electrocardiogram and echocardiography data will be available on request. Echocardiography data will be exported and shared as video and snapshot files in the .AVI and .TIFF formats, respectively. Algorithms and software will be made available in accordance with applicable NIH, IP and institutional policies on data and resource sharing. Sharing of unique research resources, including the sharing of biomedical research resources, will be governed by the performing institution's IP Office. The PI will be the point of contact for data sharing and management.