Primary objective
8+/−2
DIFFERENTIATED THYROID CANCER, PND, REMISSION
To assess the non-inferiority of total thyroidectomy alone as compared to total thyroidectomy with bilateral prophylactic central compartment neck dissection in terms of the rate of complete remission (excellent response) at 1 year after randomization, for differentiated thyroid cancer cT1bT2N0. We hypothesize that the rate of complete remission after thyroidectomy alone is not inferior to the rate of complete remission after thyroidectomy with PND by more than 5% at 1 year.The primary criterion is the rate of patients Normal whole body scan (SPECT-CT) performed after the administration of 30 mCi (1.1 GBq) of 131I administered within 2–4 months following surgery,Normal neck ultrasound 8+/−2 months after the Unstimulated ultrasensitive thyroglobulin while on L-thyroxine treatment (usTg/LT4) ≤ 0.2 ng/mL) without anti-Tg antibodies (TgAb) 8+/−2 months after administration of In this network’s previous study, 94% of the low-risk patients (including 12% T2N0) were in complete remission 1 year after surgery and administration of 131I after rhTSH [