Secondary outcomes
macrosomia, weight gain
EVENT, RECRUITMENT, NEONATAL HYPOGLYCAEMIA, REGRESSION, EVENTS, APPENDIX
FGM enabled to reveal all nocturnal hypoglycaemic events during the first month of the study in the study group (mean incidence of 15 events/month). In 6 out of 49 patients (12.24%) we recorded one episode of hypoglycaemic event level 2 (glucose concentration less than 54 mg/dl). We were not able to compare it with the control group, as participants from the control group measured glucose concentration only once between 2:00 and 4:00 at night. Therefore, in the control group the mean incidence of nocturnal hypoglycaemic events was 2 events per month, but the result was not comparable with the FGM group.We analysed HbA1c concentration at the 1st, 3rd and 4th visit and found no significant difference between the groups (Supplementary Appendix 1). Delta HbA1c concentration, defined as difference between HbA1c measured between 34–36 weeks of gestation and HbA1c measured at the recruitment visit also did not differ significantly between the groups (ΔHbA1c for SMBG group was 0.1% (−0.1–0.2) and for FGM group 0.05% (−0.2–0.2), We found no significant difference in incidence of caesarean section (OR 0.84, 95% CI 038–1.87) and weeks of gestation at birth between the groups (Logistic regression did not reveal strong association between mean glycaemia during the first month and incidence of neonatal hypoglycaemia, with OR 0.96 (95% CI 0.88–1.05) for fasting mean glycaemia and OR 0.99 (95% CI 0.91–1.08) for postprandial mean glycaemia, respectively. However, postprandial glucose concentration was correlated with the incidence of fetal macrosomia (ROC AUC 0.704, 95% CI 0.546–0.862) (Fig. Relationship between glycaemia during the first month of the study and birthweight We used Pearson’s correlation to analyse, whether mean glucose concentration during the first month of the study was correlated with birthweight, but we found no strong relationship between either fasting mean glycaemia (Gestational weight gain, defined as difference between weight at the 3rd follow up visit and weight at the recruitment visit, did not differ significantly between the groups (The study group more frequently modified their diet habits, when compared to the control group. Median (IQR) EAT score did not differ at the recruitment visit (34 points (28–36) for FGM compared to 33 points (28–35) for SMBG, 