Effusion and pleural biopsy analysis
tumor
TUMOR
Pleural fluid and serum samples were obtained from patients both pre-treatment (baseline) and post-treatment (at 24, 48, 72, and 96 hours, and on days 2, 3, and 60). All specimens available were assessed for a panel of effector and suppressive cytokines using a 41-plex MILLIPLEXValues represent the mean of the duplicate wells ± standard deviation. These data were analyzed using IS 2.3 software (Luminex Software, Inc., Riverside, CA), Microsoft Excel and GraphPad Prism. Additionally, RNA isolation was performed on FFPE sections of tumor biopsies taken pre- and post-treatment using the RNeasy