Materials and methods
inflammation
MAY, INFLAMMATION
This prospective single-blind randomized placebo-controlled clinical trial was performed at Ramezanzadeh Radiotherapy Center in Yazd, Iran from September 2020 to May 2021. Following ethical approval from the Ethics Committee of Shahid Sadoughi University of Medical Sciences (ID: IR.SSU.MEDICINE.REC.1399.112), 45 patients who developed RT-induced oral inflammation were included and randomly divided into three groups. This study was also registered in the Iranian Registry of Clinical Trials (IRCT) with the registration ID of IRCT: IRCT20190810044500N17 (13/08/2021). The participants were asked to sign a written informed consent form. All experiments were performed in accordance with relevant guidelines and regulations.