4.9. Statistical Analysis
Data were expressed as mean ± SD for normally distributed. The incremental areas under the postprandial curve (iAUC) or the decremental AUC (diAUC) and maximal change were used to evaluate the overall response during postprandial period. AUC was calculated using GraphPad Prism (version8.0.1, GraphPad Software, Inc., La Jolla, CA, USA). Maximal change was calculated by subtracting fasting concentrations from maximal value or by subtracting minimal value from fasting concentrations. Analysis of variance (ANOVA) for repeated measures was used to analyze the time and meals interaction within subject groups and the time and group interaction within meals. SCIEX Analyst Work Station Software (Version 1.6.3, AB SCIEX, Framingham, MA, USA) was employed for MRM data acquisition and processing. MS raw data (wiff) files were converted to the TXT format using MSconventer. In-house R program and database were applied to peak detection and annotation. All these analyses were performed using SPSS (version 22.0, Chicago, IL, USA). Values with 