Introduction
muscle invasive bladder cancer
COMPLICATIONS
Neo-adjuvant chemotherapy and radical cystectomy (RC) is the standard management for muscle invasive bladder cancer (BCa) or non-muscle invasive BCa failing intravesical BCG [The details of PLND during RC including the limits, precautions, the outcome, the prognostic benefits and the complications are all well described [We hypothesized that, en-block PLND with the RC specimen may be oncologically better, due to lack of interruption of lymphatic channels between the bladder and the draining LNs, than after bladder removal. Thus, the present study was conducted to compare the oncological outcome of performing ePLND before or after RC in 200 patients in a prospective randomized manner.