1. Introduction
inflammation, natto, CVD, metabolic disorders
CARDIOVASCULAR DISEASE, CVD, INFLAMMATION, METABOLIC DISORDERS, CHRONIC INFLAMMATION
Systemic low-grade inflammation plays a key role in the development of cardiovascular disease (CVD) but the process may be modulated by consuming fermented soy foods. Here, we aim to evaluate the effect of a fermented soy powder Q-CANSystemic chronic inflammation is a contributing factor to cardiovascular disease (CVD) and metabolic disorders [A major oilseed crop, the soybean (Subsequently, multiple human clinical trials tested various types, schedules, and doses of dietary soy or soy isoflavone-rich foods and supplements. Given the heterogeneity in population and design, these studies produced interesting but divergent results. Soy products inhibited inflammatory markers in postmenopausal women [Many traditional soy foods such as tofu, tempeh, miso, and natto are fermented products that require the involvement of microorganisms or fungi to produce. Microbial fermentation elaborates hydrolytic protease and β-glucosidase enzymes that produce bioactive peptides and convert glycosidic isoflavone glycosides into aglycones which improve the digestibility of soybeans, increasing the quantity and bioavailability of its bioactive principles, and may exert anti-inflammatory effects [