Confounding factors in the cardioprotective effect of RIPC
diabetes, hypertension, Comorbidity
HYPERTENSION, HYPERLIPIDEMIA, DIABETES
The results of CONDI-2/ERIPC-PPCI demonstrated that RIPC had no benefit on the long-term clinical outcomes of STEMI patients [Comorbidity and medication are important confounding factors of RIPC because they may affect the response of the myocardium to IRI. Hyperlipidemia, diabetes, and hypertension can increase the myocardial IRI and reduce the cardioprotective effect of RIPC [