Statistical analyses
All analyses were conducted in the statistical software environment R version 4.0.3 (R Core Team, 2020). We summarized the patients’ characteristics overall and by study group. In addition, we present the summary statistics of the STAI-S scores at the four different time points as well as for the patient and physician questionnaires at each time point by study group and histological result. To evaluate the impact of the intervention on STAI-S, we used a log-transformed linear mixed effects model with the intervention condition as a predictor and the natural log of STAI-S as the outcome using the package lme4 [