Side effects
toxicity, gastrointestinal toxicity, genitourinary toxicity, Toxicity
ADVERSE EVENT
In the Phase I part of the study, no DLT was identified within 90 days of therapy initiation; hence, dose escalation continued through all intended dose levels. As a result, three patients were enrolled in each dose level (The number of patients experiencing GI and GU toxicity by grade and time is shown in Click here for additional data file.Genitourinary and gastrointestinal toxicity according to grade and time.GI, gastrointestinal toxicity; GU, genitourinary toxicity.
Toxicity graded according to Common Terminology Criteria of Adverse Events, version 4.No grade 3 or more toxicity was reported.Time period: from day 1 of stereotactic radiation therapy and up to 90 days after the first fraction or more than 90 days after the first radiation fraction.