Statistical Analyses
pneumonitis
PNEUMONITIS
Descriptive statistics were used to summarize demographic and clinical characteristics of patients, stratified by treatment group and across all RWD patients and RCT patients. Radiotherapy characteristics among patients with suspected pneumonitis identified by structured data were summarized for the RWD patients. Incidence proportions were calculated as the number of TAP cases divided by the total number of patients in each treatment group. Stratified analyses were conducted to provide results for patients with and without a past medical history (PMH) of pneumonitis. These primary analyses were conducted for both the RCT patient cohort and the RWD patient cohort. Confidence intervals for incidence proportions were calculated on the basis of the Wilson method for binomial probabilities. All analyses were performed in R programming language, version 3.3.2 (R Foundation for Statistical Computing).