CGM parameters
mean blood glucose
Subcutaneous interstitial glucose monitoring was conducted using a CGM system (Medtronic, Inc,Minnesota,USA) during the screening, lead-in, and after 12-week treatment period, for three consecutive days. The study parameters included mean blood glucose level (MBG), standard deviation of blood glucose (SDBG), mean amplitude of glycemic excursions (MAGE), postprandial glucose excursions (PPGE), largest amplitude of glycemic excursions (LAGE), mean of daily difference (MODD), and time-in-range between 3.9 and 10.0 mmol/L (TIR). The area under the curve (AUCpp) was calculated within 4 h of the start of each meal.