Study Outcomes and Follow-Up
death, cardiovascular death, OAC, stroke, SE, embolism
STROKE, SECONDARY, EMBOLISM
All participants in the LOOP Study were followed up from randomization until death or January 28, 2021, with 0 participants lost to follow-up. As in primary reporting of the LOOP Study, the primary outcome for this secondary analysis was a composite end point of stroke or systemic embolism (SE). Secondary outcomes were the composite end point of stroke, SE, or cardiovascular death and the end point of all-cause death. Other outcomes of interest included diagnosis of AF, ILR-detected AF episode ≥24 hours, and OAC initiation. The primary and secondary outcomes were adjudicated by a clinical end point committee blinded to randomization assignment in accordance with prespecified criteria,