Introduction
dysplasia, histologic disease, ulcerative colitis, UC
DYSPLASIA, REMISSION, INFLAMMATORY DISEASE, ULCERATIVE COLITIS
Treatment of ulcerative colitis (UC), a chronic, progressive, debilitating inflammatory disease of the gastrointestinal tract [Achievement of endoscopic healing has emerged as an important treatment goal for patients with UC as several studies suggest that endoscopic healing is associated with long-term clinical remission, decreased colectomy rates, and decreased rates of dysplasia [At present, there are few data available on the impact of a composite histologic and endoscopic endpoint on longer-term outcomes, particularly early in the treatment cycle. Two endpoints that combine endoscopic and histologic disease activity have been proposed and are currently being utilized in clinical trial settings [