Authors’ contributions
RECRUITMENT
YKS and XHH were responsible for the overall conception and design of the study and for the interpretation of the data, writing, revising and editing of the manuscript. XSH, XC, ZPW, YPL, YL, WZ, HZ, MXY, DJ, MXW, MJC, XZ, LMD, YW, XBY, PXW, BH, XHH and YKS were involved in patient recruitment and data acquisition. XBY and PXW wrote the manuscript. All authors read and approved the final manuscript.