Participants
MDD, DSM-IV-TR
Participants were recruited at Vanderbilt University Medical Center (VUMC; Nashville, TN) through outpatient referrals and response to community advertisements. Enrollment ranged from June 2015 through March 2020.Criteria for inclusion required subjects be age 60 years or older and meet DSM-IV-TR criteria for MDD with a Montgomery-Asberg Depression Rating Scale (MADRS) (Montgomery & Asberg, All participants provided written informed consent. The VUMC Institutional Review Board approved the study. The study was registered with ClinicalTrials.gov (NCT02332291).