Findings
white matter lesions
In this post hoc analysis of a randomized clinical trial with 458 participants, intensive blood pressure treatment was associated with reduced progression of white matter lesions, notably in deep white matter tracts, and supported by corresponding changes in fractional anisotropy and mean diffusivity. Intensive blood pressure treatment was also associated with improved cerebral blood flow in the occipital lobe, parietal lobule, frontal gyrus, and cuneus.