Retention of study participants
All study measurements are done during regular follow-up visits to enhance compliance to the protocol. The team involved in this study was trained to motivate participants to adhere to the study protocol. Different flavors of the study product are included to enhance compliance. All participants receive more drinks than needed for the follow-up time which allows participants to choose their favorite flavor and leave out the flavors they like less.When the study product is not tolerated well, the researcher will discuss possible solutions with the individual study participant. Examples of possible solutions are:Spread the drink throughout the dayDissolve the drink in extra waterSkip intake of the study product for several days and then try againIf despite the above advice participant does not tolerate the drinks, intake may be stopped. Participant does not need to withdraw from the study, since compliance to the product is one of the study parameters. These patients won’t be taken into account in the per-protocol analysis if their compliance is below 70% (see the “