Primary Outcome
gram-negative, postbiopsy, infections, postbiopsy infection, Infection
SECONDARY, INFECTIONS, INFECTION
Infection rates within 7 days postbiopsy were 4.3% (n = 28) using empirical prophylaxis (CG) and 2.5% (n = 16) using culture-based prophylaxis (IG) (stratified Results of the primary and secondary outcome measures per group. Point estimates of effects with 95% confidence intervals for the difference between the control and intervention groups are depicted.Type of early and late postbiopsy infections per group.In the IG, patients with an early postbiopsy infection (n = 16) used the following prophylaxis: ciprofloxacin (88%); fosfomycin (6%), and pivmecillinam combined with amoxicillin/clavulanic acid (6%). None of these patients had prophylaxis-resistant gram-negative bacteria (GNB) in the culture of the (second) rectal swab collected immediately before PB (not used for choosing antibiotic prophylaxis).