Author Contributions
RECRUITMENT
Conceptualization of this study, including methodology and study design, was done by ML, SvG, NdB, MDi and GD. Patient recruitment and data collection was done by ML, AV, SvG, and all authors. MDu and AvB received the therapeutic drug monitoring results and communicated the dose adjustments to EC, who communicated the dose adjustment with the local site investigator. AV and ML performed the data analysis in consultation with NM. All authors contributed to data interpretation. AV and ML wrote the manuscript; all other authors revised the manuscript. Mark Löwenberg acts as the submission’s guarantor. All authors had access to the study data and reviewed and approved the final manuscript.