Study design
DISEASES, DISEASES
The present study is part of the LIFE Child study conducted at the Research Center for Civilization Diseases in Leipzig (Germany). LIFE Child is a longitudinal cohort study investigating the development of children and adolescents from pregnancy until early adulthood with a particular interest in the origins of non-communicable diseases. The annual visits comprise a comprehensive physical examination, collection of bio-samples, and several questionnaires regarding sociodemographic, psychological, and lifestyle characteristics [The following analysis is based on cross-sectional data collected between September 2018 and February 2020. In cases of multiple visits per child, the most recent visit was chosen.LIFE Child is conducted in accordance with the Helsinki Declaration and was approved by the Ethics Committee of the Medical Faculty of the Leipzig University (Reg. No. 264–10-19,042,010). All parents gave written informed consent for them and their children to be included in the study. An additional written informed consent was obtained from adolescents age 12 and above.