Enrollment and rates of study completion
Alzheimer, blood amyloid status, MAPT
ALZHEIMER
Among the 1680 participants in MAPT and 1503 in its biobank, 483 amyloid blood assays were performed for this analysis at 12 (448 subjects) and 24 months (35 subjects). These subjects (Trial profile for the amyloid blood MAPT study. MAPT multidomain Alzheimer’s preventive trial, MI multidomain interventionThe ITT population included 161 positive and 322 negative amyloid subjects based on plasma Aβ42/Aβ40 ratio. In the ITT subgroup with positive amyloid blood status, 128 (79.5%) and 84 (52.2%) subjects completed respectively 36- and 60-month visits. In ITT subgroup with negative blood amyloid status, 273 (84.8%) and 215 (66.8%) subjects completed 36- and 60-month visits.