Predictors of Nocebo Reduction
Nocebo hyperalgesia, anxiety, hyperalgesia
GROUP B, REGRESSION

Table Summary of Hierarchical Regression Steps, the Explained Variance, and the ANOVA Tests of the Increase in Explained Variance From One Step to the Other (Only the variables kept in the model after forward selection are presented in the final model. 


In step 1, the group variable significantly explained 35% of the variance in the nocebo change score. In line with the primary findings of the larger study,Summary of Final Model After Forward Selection Predicting Nocebo Change with Continued Only the variables kept in the model after forward selection are presented in step 3 and 4.Group A: Counterconditioning, Group B: Extinction, Group C: Continued Nocebo Conditioning; 


Summary of Final Model After Forward Selection Predicting Nocebo Change With Extinction as Reference Group (Only the variables kept in the model after forward selection are presented in steps 3 and 4.Group A: Counterconditioning, Group B: Extinction, Group C: Continued Nocebo Conditioning; 


In step 2, nocebo hyperalgesia significantly explained an additional 26% of the variance in the nocebo change score, where a larger induction of nocebo hyperalgesia was associated with a significantly larger nocebo reduction (In step 3, the inclusion of psychological characteristics significantly explained an additional 9% of the variance in the nocebo change score, and in step 4, the inclusion of moderators significantly explained an additional 9% of the variance. Because multiple variables were entered in steps 3 and 4, their individual contribution was interpreted as part of the final model created with forward selection.The forward selection resulted in the selection of group, nocebo hyperalgesia, optimism, trait anxiety, the interaction term of group and nocebo hyperalgesia, and the interaction term of group and optimism as the predictor variables in the final model (see Tables Nocebo hyperalgesia and intervention group as predictors of nocebo change. Note that higher levels on nocebo change indicate a larger reduction in nocebo effects from part 1 to part 2.Optimism and intervention group as predictors of nocebo change. Note that higher levels on nocebo change indicate a larger reduction in nocebo effects from part 1 to part 2.