Trial design {8}
COPD
CHRONIC OBSTRUCTIVE PULMONARY DISEASE, COPD
The ROTA-USE STUDY is designed as a pragmatic, parallel arm, open-label, multicenter, spontaneous, no-profit, randomized, controlled, trial requiring non-significant risk medical devices. Figure Research design of the study protocol. NIV, noninvasive ventilation; COPD, chronic obstructive pulmonary disease