Patients
primary headache, pain, psychiatric, migraine, medication-overuse headache
HEADACHE DISORDERS, CARDIOVASCULAR DISEASE, TEMPOROMANDIBULAR DISORDER, SYNDROMES, MIGRAINE
DELIVER enrolled adults (18‒75 years [inclusive]) with migraine and documented evidence of 2–4 previous preventive treatment failures in the prior 10 years. Key inclusion criteria included: onset of migraine (International Classification of Headache Disorders 3rd edition [ICHD-3] [Key exclusion criteria included: failure on a previous treatment targeting the CGRP pathway; confounding and clinically significant pain syndromes; diagnosis of temporomandibular disorder; history or diagnosis of other primary headache types; history of clinically significant cardiovascular disease; uncontrolled and/or untreated psychiatric condition; and use of preventive migraine medication within 1 week prior to the screening visit. Patients with concurrent diagnosis of medication-overuse headache (defined by clinical ICHD-3 criteria [