Procedure
MSAQ
MAY, MOTION SICKNESS
Eligible participants were randomized to take Tradipitant 170mg or placebo approximately 60 minutes prior to the initiation of boat travel. Groups of between 10 and 26 participants each participated in one of seven boat trips lasting between 237 and 250 minutes, except where extreme sea conditions limited one trip (Boat 5) to 148 minutes. Boat travel occurred in the Pacific Ocean near Los Angeles between January and May 2019. Participants rated their motion sickness symptom severity using the MSSS in 30-minute intervals throughout the trip. Participants also completed the PGI-S and MSAQ approximately 60 minutes after the conclusion of the trip. Additional information about the study procedure is available in the study efficacy report [