Background and Aims
arterial stiffness, bleeding, thrombus, airway inflammation
BLEEDING, THROMBUS, ARTERIAL STIFFNESS, OXIDATIVE STRESS, ENDOTHELIAL DYSFUNCTION
The electronic cigarette (EC) was introduced in 2003 as an alternative to traditional cigarette smoking. Over the years, the use of ECs has steadily increased across the world, especially among adolescents. This is partially due to major marketing efforts by the EC industry and e-liquid flavours especially targeting youth [Studies targeting EC-related health effects have demonstrated increased airway inflammation and obstruction, endothelial dysfunction, increased arterial stiffness and oxidative stress following EC use with e-liquids containing nicotine [The aim of the present study was to further investigate the impact of EC aerosol on vascular health applying well-established methods for assessing vascular function and haemostasis. Haemostasis was investigated by the Total-Thrombus-formation analysis system (T-TAS), which has been used for bedside assessment of thrombus formation in whole blood, evaluate anti-platelet therapies, anticoagulants and risk of bleeding during catheter interventions [