Adverse events
fatigue, diarrhea, leukopenia, anemia, nausea,, headache, alopecia, anorexia
ADVERSE EVENT, LEUKOPENIA, ADVERSE EVENTS, THROMBOCYTOPENIA, ANEMIA, ADVERSE EVENT, EVENTS, ALOPECIA, ANOREXIA
The following adverse event management guidelines are intended to ensure the safety of each participant while on the study. The descriptions and grading scales found in the revised NCI Common Terminology Criteria for Adverse Events (CTCAE) version 5.0 will be utilized for AE reporting. All appropriate treatment areas should have access to a copy of the CTCAE version 5.0.Most likely adverse events (>20%) associated with abemaciclib include anemia, diarrhea, nausea, vomiting, fatigue, anorexia, leukopenia, and thrombocytopenia. Abemaciclib (LY2835219) in combination with other agents could cause an exacerbation of any adverse event currently known to be caused by the other agent, or the combination may result in events never previously associated with either agent. The most common adverse events associated with temozolomide (>10%) include alopecia, fatigue, nausea, vomiting, headache, and diarrhea.