References
OXIDATIVE STRESS, OXIDATIVE STRESS
General study flowchart. Abbreviations: EG1000, group supplemented with 1000 mg/day of RV; EG500, group supplemented with 500 mg/day of RV; PG, placebo group.SIRT1 concentration in study groups: baseline and after six months. Data are presented as mean ± SE. A statistically significant increase (1.5 ± 0.15 vs. 3.1 ± 0.20 ng/mL; Clinical parameters (BMI and blood pressure) at baseline and after six months in the study groups.BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure. Data are presented as mean ± SD. ANOVA of repeated measures.Biochemical parameters of the study groups at baseline and after six months.HbA1c: glycosylated hemoglobin; CRP: C reactive protein. Data are presented as mean ± SD. ANOVA of repeated measures. Tukey test as post hoc, * OS markers in the study groups: baseline and after six months.LPO: lipoperoxides; 8-Iso: isoprostanes; GPx: glutathione peroxidase; Cat: catalase; TAC: total antioxidant capacity; SOD: superoxide dismutase; OSS: oxidative stress score. Data are presented as mean ± SD. ANOVA of repeated measures. Tukey test as post hoc, * Oxidative stress index in the study groups: baseline and after six months.OS: oxidative stress. McNemar test, * 