Principal findings
cystitis, UTIs
DISEASE, CYSTITIS, COMPLICATIONS, UTI
The multimodal intervention consisting of guideline recommendations for GPs and patients, provision of regional resistance data, and quarterly feedback of individual antibiotic prescribing proportions, benchmarking, and telephone counselling resulted in a decrease in prescription proportions of second line antibiotics for uncomplicated UTIs in women. Additionally the intervention group noted a reduction of all antibiotics prescribed for this indication, with no evidence for an increase in complications.Disease specific quality indicators for outpatient antibiotic prescribing in Europe recommend a prescription rate of less than 5% for quinolones in adult women who were diagnosed with cystitis.Our study showed a reduction of antibiotic prescription proportions and an increase of UTI cases treated without antibiotics, which is in line with the recommendation of many guidelines.