Primary and Secondary End Points
acute kidney injury, ischemia-reperfusion injury
EVENTS, CDA, BRAIN DEATH
Abbreviations: AST, aspartate aminotransferase; CDA, combined drug approach; DBD, donation after brain death; FAS, full analysis set; IRI, ischemia-reperfusion injury; ND, not determined because of an absence of events in 1 group; PPS, per protocol set analysis.SI conversion factor: To convert AST to μkat/L, multiply by 0.0167.Treatment effect is expressed as the geometric mean ratio. Treatment effect is expressed as the unadjusted odds ratio and 95% CI. In cases with less than 5 events in at least 1 group, the exact 95% CI and exact Treatment effect is expressed as an unadjusted hazard ratio from a Fine-Gray model treating mortality as a competing risk. In each group, the percentage at 1 year derived from the cumulative incidence curve is given.Data were missing for 4 in the CDA group and 4 in the control group.An acute kidney injury score of 1 indicates risk; 2, injury; and 3, failure. The ordinal character of the score was kept (ie, the reported odds ratios and The treatment effect is the Hodges-Lehmann estimator and equals the median of all pairwise differences. Data were missing for 7 each in the CDA and control groups.