Six weeks of CoQ10 or NR supplementation was associated with significant alterations in plasma fatty acyls (fatty acids), glycerolipids (triglycerides and diacylglycerides), glycerophospholipids (PEs, LPEs, LPCs, and PCs), and sphingolipids (ceramides and glucosylceramides).
To investigate systemic plasma lipid profile changes in response to NR and CoQ10, we assessed compositional changes within major lipid classes compared with placebo. We found a systematic increase in fatty acyls and a decrease in glycerolipids after CoQ10 treatment compared with placebo (