Conclusion
lupus disease, lupus
DISEASE, LUPUS, COMPLICATIONS
Taken together, according to the findings of this study, the addition of 1800-mg NAC to the treatment regimen of patients with lupus can improve the outcomes of the disease and decrease the activity and complications of lupus disease. Therefore, it is recommended that rheumatologists consider NAC supplementation in the treatment of these patients. It should be noted that we were unable to check the statistical comparison by the diet of the subjects as a confounder factor, which might have an effect on the final outcome. Future studies are also recommended to determine the clinical significance of this study in a larger sample size, with different doses of the drug, considering the severity of lupus disease and follow-up within 1 year. Moreover, NAC adjuvant drug therapy’s effect should be investigated in reducing the dose of the treatment regimen of immunosuppressive drugs in these patients.