Effect of ABL on bone geometry indices
Comparisons of bone geometry indices (OD, CoTh, and CSA) from baseline between the ABL and PBO groups over time are shown in Fig. Mean percent change from baseline in DXA-based bone geometry HSA indices. (Compared with PBO, 78 weeks of ABL injection showed a significant difference in CoTh at the NN (4.5%; 95% CI, 1.67, 7.29), IT (5.3%; 95% CI, 3.48, 7.21), and FS (3.6%; 95% CI, 1.85, 5.42), and in CSA at the NN (5.5%; 95% CI, 3.65, 7.26), IT (4.7%; 95% CI, 2.97, 6.43), and FS (2.7%; 95% CI, 1.20, 4.12).