Methods
VTE, TG, DVT
DVT
We performed bidirectional MR analysis of classical lipids (LDL, HDL and TGs) and VTE (DVT and PE). First, we used classical lipids (LDL, HDL and TGs) as exposure variables to conduct two-sample MR analysis with VTE (DVT and PE). In addition, to further clarify whether VTE affects lipids, we used VTE as an exposure variable to analyse the causal relationship between VTE and classical lipids. The hypothesis of this study is that there is no causal relationship between VTE and classical blood lipids.The research design is shown in Fig. Analysis flow chart. We performed bidirectional MR analysis of classical lipids (LDL, HDL and TG) and VTE (DVT and PE). First, we used classical lipids (LDL, HDL and TG) as exposure variables to conduct two-sample MR analysis with VTE (DVT and PE). In addition, to further clarify whether VTE affects lipids, we used VTE as an exposure variable to analyse the causal relationship between VTE and classical lipids.