Statistical analysis
IBM SPSS Statistics for Windows, Version 21 (IBM Corp., Armonk, NY, USA) was used in the statistical analysis. The categorical variables were analyzed using Pearson’s chi-square test.According to the number of subjects in the eyes, chi-square analysis with Fisher’s exact test and Monte Carlo simulations were used. The Wilcoxon signed-rank test was used for within-group comparisons for the different time periods.To compare between groups, the normality of the data was determined using the Kolmogorov-Smirnov test, and Mann Whitney U tests were performed for comparisons. The significance level for all tests was (