Introduction
toxic, open-angle glaucoma
OCULAR HYPERTENSION, OPEN-ANGLE GLAUCOMA, CORNEA
Brimonidine tartrate is a selective Preservative-free IOP-lowering medication packaged in single unit-dose pipettes with fewer additives has been gradually substituted for a large portion of preserved medications. Preservative-free medication is easy to use, allows for easy counting of doses, and, most importantly, is less toxic to the cornea, resulting in reduced irritation and dry eyeThe main purpose of this study was to prospectively compare the efficacy and safety of preservative-free brimonidine tartrate 0.15% to preserved brimonidine tartrate 0.15% with regard to corneal surface assessment, IOP reduction, safety, and adherence rates in patients with open-angle glaucoma or ocular hypertension. Moreover, to evaluate the potential benefits of preservative-free brimonidine, ocular and systemic parameters, and questionnaire-based patient satisfaction and drug tolerance scores were analyzed.