Author contributions
RECRUITMENT
Study concept and design was the responsibility of A.N., T.J.P., G.R. and K.E.H. Data collection and analysis was conducted by K.E.H., L.H.F., J.N.P., G.R., A.N., A.D., O.E.G., S.P. and J.W. Patient recruitment and sample collection was carried out by B.G., L.V.M. and T.T. Manuscript writing was the responsibility of A.N., T.J.P., G.R. and K.E.H. All authors reviewed and approved the final manuscript for submission.