Funding
This study was supported by the National Natural Science Foundation of China [grant number, 8187050959, YG; 82001777, FX; 81901115, QC]; the Public welfare development and reform pilot project of Beijing Medical Research Institute [grant number, JYY 2019–5, JT]; and the CAMS Innovation Fund for Medical Sciences [grant number, 2019-I2M-5–021, JT].