Study Drug Administration
intolerable adverse reactions
DRUG WITHDRAWAL, DISEASE PROGRESSION
Subjects orally took Anlotinib capsules, 12 mg/day, 1 capsule once daily before breakfast by study nurse. It was taken continuously for 2 weeks, followed by 1 week of drug withdrawal, that was, 3 weeks (21 days) as a course of treatment. Continuous administration until disease progression or intolerable adverse reactions.