Follow-Up
death
After the end of treatment, males were followed up with every 6 months for the first 5 years and annually thereafter. A serum PSA was obtained at each follow-up. In addition to routine follow-up assessment, restating with a bone scan and pelvis magnetic resonance imaging or computed tomography were performed at the time of PSA failure. Salvage ADT was recommended when PSA levels rose to approximately 10 ng/mL. All patients were followed from the date of random assignment until death, and the cause of death was centrally reviewed.