Conclusion
cognitive decline
DISEASE PROGRESSION
The 6-month MT physical exercise intervention did not present evidence of slowing down cognitive decline neither improving neuropsychiatric symptomatology, and quality of life of older adults with major NCD. A MT intervention can be an effective way to slow down cognitive decline, manage challenging behaviors and improve the quality of life of individuals with NCD, but further research is necessary to attest the influence of this training methodology. There is still a long way to go in what concerns physical exercise recommendations for people with major NCD, but, in the absence of a cure or disease-modifying therapy, it is of utmost importance to explore the potential effects of validated methodologies that might slow down the disease progression or alter its course, delaying or avoiding nursing-home placement.