Co-existing autoimmune diseases
rheumatoid arthritis, Sjögren syndrome, SS, RA
RHEUMATOID ARTHRITIS, REMISSION, DISEASE
Both serologic remission and clinical improvement were observed in 2 patients with Sjögren syndrome (SS) at 12 weeks post infusion, as shown in decreased anti-SSA autoantibodies, decreased EULAR SS patient reported index and EULAR SS disease activity index, increased unstimulated salivary flow rate, and prolonged tear breakup time and Schirmer’s test. (Supplementary Table In addition, the patient with rheumatoid arthritis (RA) showed improvement in RA disease activity at 12 weeks post infusion. Disease Activity Score in 28 joints and erythrocyte sedimentation rate (DAS28ESR) decreased from 4.698 (indicating an active status) to 1.987 (indicating a remission stage), and tender joint counts decreased from 24 to 0.