Statistical analysis
The Full Analysis Set (FAS) population was used in these subgroup analyses. This population was defined as all randomized patients who received at least one dose of antiemetic treatment and chemotherapy and had a record of any data post randomization. Following the intent‐to‐treat principle, patients were assigned in the analyses to the group they were initially randomized. It should be noted that the CR rates during the traditional overall (0‐120h) phase presented in the primary paperFor the efficacy endpoints, the Pearson's chi‐square test was used to compare proportions in the overall MEC group and separately in the subset of the MEC group with risk factors. For this purpose, the procedure FREQ of SAS version 9.4 was employed.