Participant timeline {13}
RECRUITMENT
The patient-participant timeline was created according to SPIRIT guidelines [We enrolled our first participant on 7 February 2022. We expect to enrol the final participant at the end of 2024. The total recruitment period will be 3 years. Approximately 40% and 45% of the sample will be recruited in 2023 and 2024, respectively. The 12-month follow-up will be completed at the end of 2025, followed by data analysis, manuscript preparation and submission in 2026 (Table A GANTT schedule of the study