Study design and setting
BLOOD DISEASES
This single arm, non-randomized, off-label clinical trial was approved by the Ethics Committees at University of Peshawar (Ref No. 507/EC-FLES-UOP/2022) and Northwest General Hospital & Research Centre Peshawar (Ref No. NWGH/DMER/EC/07-1) and is in compliance with the ethical princliples of Declaration of Helsinki. The study was conducted at Blood Diseases Clinic (BDC) Peshawar from January 2018 till December 2020. This trial is registered at 