DISCUSSION
seizure, EGTCS, epilepsy
EPILEPTIC SEIZURES, EPILEPSY
This study was performed on patients with EGTCS. According to our literature review, the majority of clinical investigations on the effect of melatonin in epilepsy have been performed on children, and fewer studies have been conducted on its influence on seizure outcome, neuroprotective effect, or sleep quality in adult epilepsy patients (Gupta, Gupta et al., Our findings suggested that patients treated with melatonin significantly benefited from reduced severity of epileptic seizures; however, in terms of the number of attacks, this reduction was not statistically significant. Sleep quality has also improved in patients treated with melatonin. There was no significant difference between the two groups in terms of EEG alterations. Melatonin is an endogenous hormone that inhibits brain excitability by acting on the MT1 and MT2 receptors (Liu et al., Peled et al. (Melatonin has a substantial influence on CNS in terms of regulating sleep and waking patterns (Banach et al., Melatonin has also been demonstrated to be safe in human tests at dosages ranging from 1 to 300 mg, with no negative side effects identified in the investigations (Doolen et al., 