Intervention
EPS
Children received either capsules of ω3-LCPUFAs or placebo capsules. ω3-LCPUFAs were administered in the form of 500 mg soft capsules of natural TGs, made from gelatin, formulated without artificial colors or flavors, molecularly distilled, and of pharmaceutical grade (Nordic Naturals, Inc., Watsonville CA, USA). The omega dose was administered at a rate of 0.100 g/kg of baseline body weight/day. The ω3-LCPUFAs comply with the principles established for fats according to the European Pharmacopoeia Standard (EPS) and according to the Council for Responsible Nutrition (CRN) and the Global Organization (CRNGO). Consequently, ω3-LCPUFAs are a safe product that does not exceed the maximal allowances for contaminants such as peroxides, heavy metals, dioxins, and PCBs. The placebo capsule contained 500 mg of sunflower oil (Progela, S.A. de C.V., México). All capsules contained vitamin E to act as an antioxidant. The odor and appearance of the ω3-LCPUFA capsules and the placebo capsules were comparable, and both were strawberry-flavored to mask their taste. During the study time, all the participants were provided with an oral supplement of the brand Fressenius