Association between broad pre-infection antibody reactivity to HIV and C or V epitope reactivity
infection
INFECTION
We next compared pre-infection HIV-1 VARscores for participants with vs. without pre-infection reactivity to the C or V epitope (adjusted fold change >1 vs. adjusted fold change = 1; Association between antibody reactivity to the C and V epitopes and HIV-1 VARscore prior to infection. VARscores are an aggregate measure of the level and breadth of antibody reactivity to all peptides spanning the viral genome. The plots show HIV-1 VARscores prior to infection for participants with and without reactivity to the C epitope 