Safety
ADVERSE EVENTS, EVENTS, CYSTITIS
Treatment-emergent adverse events, including events of special interest (i.e., renal disorder/interstitial cystitis, hepatic) were monitored, and other safety assessments (i.e., hematology and serum chemistry, urinalysis, physical examination, pulse oximetry, vital signs, electrocardiogram, and Columbia-Suicide Severity Rating Scale [Modified Observer’s Assessment of Alertness/Sedation (MOAA/S) scale was used to assess the level of post-dose sedation, and the Clinical Global Assessment of Discharge Readiness (CGADR), to assess participants’ discharge readiness, based on their overall clinical status.The Cogstate computerized test battery [