Protocol deviation due to Covid-19
REPAIR-MS
SECONDARY
Due to administrative suspension of in-person research visits at UT Southwestern in the Spring of 2020 during the COVID-19 pandemic, several patients continued treatment with the study drug for longer than the originally planned 12 weeks. Some study visit data that required an in-person visit was missing due to the COVID-19 related research suspension, but all participants had baseline and end-of-study primary and secondary outcome imaging assessments performed per protocol once in-person imaging was allowed. The end-of-study imaging assessment was performed 12–16 weeks post-baseline for all but two participants, one in REPAIR-PD (end-of-study imaging performed at 25 weeks) and one in REPAIR-MS (end-of-study imaging performed at 20 weeks).