Study outcomes
weight gain, GDM, TG, diabetes
GDM, SECONDARY, ADVERSE REACTIONS, DIABETES
For the primary study outcomes, the effect of GOS on maternal gut microbiota were reported. At the same time, for those who have been followed up to the second trimester of pregnancy, based on the results of 75g oral glucose tolerance test (OGTT) at 24-28 gestational weeks (For pregnant women, baseline data such as age, gravidity, parity, BMI, history of GDM, and family history of diabetes were described. For secondary outcomes, the biochemical parameters of glucose and lipid metabolism (fasting plasma glucose (FPG), triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C)), IL-6, and gestational weight gain (GWG) in the intervention group and the control group were included respectively. As for Newborns, included gestational age, the mode of delivery, sex, birth length, birth weight, head circumference and chest circumference. We evaluated the safety and adverse reactions of prebiotics intervention.