Efficacy assessment
tooth
COLD
This study was sufficiently powered (1-β = 0.94) to demonstrate the clinical equivalence of group SC and TP. They were significantly different from group N in the aspect of the reduction of Schiff sensitivity score. A mixed-effects model was used for statistical analysis with adjustments for age, sex, and tooth position (maxilla or mandible; incisor, premolar, and molar). At 2 weeks, all groups exhibited significant desensitization of all stimuli (air-blast; p < 0.0001, cold; p < 0.0001, acid; p = 0.0199) tested in this clinical trial from baseline. At 4 weeks, all groups showed a significant reduction in air-blast, cold, and acidic sensitivity from baseline (p < 0.001) and 2 weeks (p < 0.001). Figure Schiff sensitivity score (least squares means and 95% CI) changes measured at baseline (0), 2-week, and 4-week follow-up to (