Intervention description {11a}
The intervention is based on a 12-week aerobic exercise program tailored to the individual patients by physiotherapists using the principles of frequency, intensity, time, and type (FITT) aiming to increase or maintain the physical activity level to a weekly moderate level (metabolic equivalent of a task (MET) ≥ 3) [The patients in the intervention arm will also be offered an online video lesson of 15–25 min on lifestyle guidance including general advice on healthy living by behavioral issues similar to the comparators. The patient will receive the usual medical treatment throughout the intervention.The exercise intervention and home training are monitored by training diaries including frequency, intensity, time, and type of exercise. We will use the BORG 15-point scale (rate of perceived exertion) and heart rate monitors (commercial) to monitor intensity in-session [There is solid evidence to support the appropriateness of a 12-week follow-up period when it comes to the quality of life endpoint [