Outcome and analysis
CF
Our primary outcome was the proportion of participants with CF in the cecum after each administration method. Secondary outcome was the proportion of participants with CF in the transverse colon after each administration method. Proportions were compared using a Fischer Exact test with a significance level of 0·05. We used SPSS [28·0·1·0 (142)] to perform the calculations.All X-rays were evaluated by two independent radiologists blinded to administration method or procedure (assessor blinding). When the radiologists’ reports differed, a third (blinded) radiologist re-evaluated the X-ray images.