Results
PBC
Participant age was 23.4 (± 4.6) years, height was 179.2 (± 6.7) cm tall, and body mass was 78.5 (± 10.6) kg. Although randomisation was used, there was a significant difference in height between groups; participants in the CWI group were, on average, taller than PBC participants (At rest, HR was not significantly different between groups. However, significant treatment (The cell concentrations of 14 individual immune populations for each group over time were assessed, to ascertain whether cryotherapy treatments lead to changes in immune cell subsets within peripheral blood mononuclear cells (PBMCs), as can be seen in Table Circulating cell numbers for individual study participants. CD4A significant treatment-by-time interaction was observed in the number of circulating B cells (defined by CD19 + expression) (The total number of NK cells exhibited a significant time effect between rest and post time points (Given the specific increase in CD16Phenotype of CD16