Secondary outcomes
infection
INFECTION, CNS INFECTIONS, APPENDIX
The factors associated with performing screening for asymptomatic/paucisymptomatic patients were male sex (54.6% of patients screened versus 51.4% of patients who declined screening, OR: 1.21 (95% CI [1.05, 1.40])), mild symptoms (19.1% versus 6.4%, OR: 2.8 (95% CI [2.1, 3.7])), not being screened previously (41.6% versus 31.7%, OR: 1.4 (95% CI [1.2, 1.6])), and self-assessment of a high risk of infection (17.8% versus 14.2%, OR: 1.3 (95% CI [1.1, 1.6])) (Appendix D in The factors associated with new diagnoses through screening for asymptomatic/paucisymptomatic patients were older age (OR: 1.02 (95% CI [1.01, 1.03]) per additional year), not being from France (54.4% of patients with new diagnoses versus 40% of patients who tested negative, OR: 1.7 (95% CI [1.2, 2.5])), particularly being from sub-Saharan Africa, having mild symptoms (61.6% versus 16.5%, OR: 7.3 (95% CI [5.1, 10.4])), being a case contact (29.7% versus 22.0%, OR: 1.8 (95% CI [1.2, 2.6])), and not being screened previously (57.7% versus 41.4%, OR: 2.1 (95% CI [1.5, 3.0])) (Appendix E in At the regional level, the proportion of new diagnoses through ED screening for asymptomatic/paucisymptomatic patients was higher than the proportion of positive tests through community screening for asymptomatic adults in the departments of the Paris metropolitan region (224/4,283 (5.2%) and 156,298/3,400,584 (4.6%), respectively, risk difference: 0.6% (95% CI [0.01%, 1.3%]; The proportion of new diagnoses through ED screening for all patients was higher than the proportion of positive tests through community screening for adults in the departments of the Paris metropolitan region (3,943/40,367 (9.8%) and 361,089/4,680,491 (7.7%), respectively, risk difference: 2.1% (95% CI [1.8%, 2.3%]; The estimates from ED screening were compatible with the predictions of the mathematical model, yielding a regional incidence rate of asymptomatic/paucisymptomatic infections in adults of 4.1% (95% probability ranges [2.5%, 5.7%]) and a regional incidence rate in adults (symptomatic and asymptomatic) of 9.7% (95% probability ranges [6.1%, 13.8%]).