Primary and secondary outcomes before and after the intervention in synbiotic and placebo groups.
HYPOTHYROIDISM
1: within group comparison, paired t-test2: between group comparison, independent t-test3: two-way ANCOVA analysis with adjustment for duration of hypothyroidism, age, levothyroxine dose, and physical activitySignificant results were observed for most of the domains of the QoL. The change in physical functioning (