Clenbuterol treatment increases basal- and sleeping metabolic rate
Next, we investigated if 14 days of clenbuterol treatment increased energy expenditure and altered substrate utilization. For this, we did not only measure basal metabolic rate, but also determined sleeping metabolic rate (SMR) using whole-room calorimetry, as it is known that SMR is the most sensitive measure to detect changes in energy needs. We found that sleeping- and basal metabolic rate increased by 10.2% and 5.6% (