Statistical Analysis
cardiotoxic
REGRESSION, CARDIOVASCULAR DISEASE, PCP
Participant demographics, diagnosis characteristics, and historical treatment information were analyzed with descriptive statistics. We calculated the proportion of participants with medical visits and other health care utilization and cardiovascular screening based on review of the PCPs’ medical records. Medical record documentation of prior treatment exposures was compared with known exposures from CCSS research data by McNemar test. To assess agreement among participant self-report, PCP medical records, and CCSS research data, we estimated the sensitivity, specificity, and κ (concordance) among these data sources.Univariate logistic regression models identified factors associated with having completed any cardiac screening (ECG, echocardiogram, or other cardiac imaging) in the 2 years preceding trial enrollment, with odds ratios (ORs) and 95% CIs. Variables of interest included age, sex, documentation of radiation and cardiotoxic chemotherapy exposures, documentation that the participant had increased risk of cardiovascular disease, presence of an SCP, documentation of the need for late-effects monitoring, number of existing cardiovascular conditions (as determined by PCP medical records), a recent cardiology visit, and greater PCP utilization (defined as having >3 PCP visits over the preceding 2 years; 3 being the median value). Variables with 