Competing interests
FE: had a consultancy or advisory role for AbbVie, Incyte, Janssen, and Syros, outside the submitted work. GET: research grants from Mundipharma and Alexion Pharmaceuticals, advisory board honoraria from Alexion Pharmaceuticals and Janssen-Cilag, and lecture honoraria from Novartis, Janssen-Cilag, Alexion Pharmaceuticals, and Mundipharma. Other authors declare no conflicts of interest.