INTRODUCTION
Crohn’s disease, IBD, ulcerative colitis, UC
INTESTINAL INFLAMMATION, INFLAMMATORY BOWEL DISEASE, REMISSION, ULCERATIVE COLITIS
Inflammatory bowel disease (IBD), mainly defined as either ulcerative colitis (UC) or Crohn’s disease (CD), is a chronic and relapsing intestinal inflammation involving various factors and an abnormal immune response (For decades, fecal microbiota transplantation (FMT), the administration of a fecal suspension obtained from healthy donors into the gastrointestinal tract of a patient, has been used successfully for bacteriotherapy in individuals with Currently, multiple modes of FMT administration, including colonoscopy, nasoduodenal tubes, enemas, and capsules, are available to clinicians (Here, we investigated the longitudinal dynamics of serum metabolites and the gut microbiome of bacteria in UC patients after capsulized FMT treatment. We aimed to determine the efficiency of treatment of UC patients with capsulized FMT and determine the functional factors associated with clinical remission through multiomic analyses.