Results
malignancy
PATHOLOGY
This analysis consisted of 197 samples, with 101 women in the SCSH-Sampling group and 96 women in the Sampling-SCSH group. Patient characteristics are shown in Table 
Baseline characteristicsBMI = body mass index; IQR = interquartile range; PMP = postmenopausal SCSH = saline contrast sonohysterographyComparison of histologic findings between the SCSH-Sampling and Sampling-SCSH group is shown in Table 
Comparison of histologic findings between SCSH-Samplingand Sampling-SCSH group. Values are presented as number (%)Not presentLittleModerateA lot34 (34%)27 (27%)16 (16%)24 (24%)42 (44%)26 (27%)13 (14%)15 (16%)Not presentLittleModerateA lot35 (35%)32 (32%)16 (16%)18 (18%)33 (34%)32 (33%)16 (17%)15 (16%)Not presentLittleModerateA lot7 (7%)34 (34%)26 (26%)34 (34%)5 (5%)21 (22%)28 (29%)42 (44%)Not presentLittleModerateA lot32 (32%)21 (21%)24 (24%)24 (24%)24 (25%)21 (22%)18 (18%)32 (33%)Not presentLittleModerateA lot22 (22%)27 (27%)24 (24%)28 (28%)13 (14%)25 (26%)25 (26%)33 (34%)Not presentLittleModerateA lot33 (33%)20 (20%)24 (24%)24 (24%)27 (28%)14 (15%)22 (23%)33 (34%)Table 
Comparison of histologic findings between the sufficient versus the insufficient samples. Values are presented as number (%)Not presentLittleModerateA lot36 (58%)12 (19%)7 (11%)7 (11%)40 (30%)41 (30%)22 (16%)32 (24%)Not presentLittleModerateA lot12 (19%)23 (37%)7 (11%)20 (32%)56 (41%)41 (30%)25 (19%)13 (10%)Not presentLittleModerateA lot12 (19%)33 (53%)11 (18%)6 (10%)0 (0%)22 (16%)43 (32%)70 (52%)Not presentLittleModerateA lot41 (66%)16 (26%)3 (5%)2 (3%)15 (11%)26 (19%)39 (29%)54 (40%)Not presentLittleModerateA lot30 (48%)21 (34%)8 (13%)3 (5%)5 (4%)31 (23%)41 (30%)58 (43%)Not presentLittleModerateA lot46 (74%)9 (15%)6 (10%)1 (2%)14 (10%)25 (19%)40 (30%)56 (41%)A significant difference was found for all the histological features with higher amounts of blood, endometrial epithelium, intact endometrial glands, stroma and tissue context in the sufficient samples. Oppositely, a significantly higher amount of mucus was found in the insufficient samples.Table 
Comparison of histologic findings between SCSH-Samplingand Sampling-SCSH group for the sufficient samples. Values are presented as number (%)Not presentLittleModerateA lot15 (23%)19 (29%)10 (15%)21 (32%)25 (36%)22 (31%)12 (17%)11 (16%)Not presentLittleModerateA lot26 (40%)21 (12%)12 (19%)6 (9%)30 (43%)20 (29%)13 (19%)7 (10%)Not presentLittleModerateA lot0 (0%)15 (23%)19 (29%)31 (48%)0 (0%)7 (10%)24 (34%)39 (56%)Not presentLittleModerateA lot9 (14%)12 (19%)21 (32%)23 (35%)6 (9%)14 (20%)18 (26%)31 (44%)Not presentLittleModerateA lot3 (5%)16 (25%)19 (29%)27 (42%)2 (3%)15 (21%)22 (31%)31 (44%)Not presentLittleModerateA lot8 (12%)13 (20%)21 (32%)23 (35%)6 (9%)12 (17%)19 (27%)33 (47%)Bold indicates that the statistical significance at Table 
Comparison of histologic findings between SCSH-Samplingand Sampling-SCSH group for the insufficient samples. Values are presented as number (%)Not presentLittleModerateA lot9 (25%)11 (31%)4 (11%)12 (33%)3 (12%)12 (46%)3 (12%)8 (31%)Not presentLittleModerateA lot9(25%)11(31%)4(11%)12(33%)3 (12%)12 (46%)3 (12%)8 (31%)Not presentLittleModerateA lot7 (19%)19 (53%)7 (19%)3 (8%)5 (19%)14 (54%)4 (15%)3 (12%)Not presentLittleModerateA lot23 (64%)9 (25%)3 (8%)1 (3%)18 (69%)7 (27%)0 (0%)1 (4%)Not presentLittleModerateA lot19 (53%)11 (31%)5 (14%)1 (3%)11 (42%)10 (38%)3 (12%)2 (8%)Not presentLittleModerateA lot25 (69%)7 (19%)3 (8%)1 (3%)21 (81%)2 (8%)3 (12%)0 (0%)No new cases of atypia or malignancy were detected at this pathology review by the dedicated gyneo-pathologists.