Outcomes
colorectal neoplasia, non-syndromic CRC
SECONDARY
The primary outcome was to assess whether screening uptake of FIT was greater than that of one-time colonoscopy screening, in high-risk FDR of patients with non-syndromic CRC. Screening uptake was defined as the number of compliant participants divided by the number of eligible subjects in each screening strategy. In the FIT group, subjects were considered compliant if completed at least 1 FIT and the work-up colonoscopy if a positive test occurred. In the colonoscopy group, those subjects that underwent one-time colonoscopy were considered compliant. The secondary outcome was to determine the detection rate of advanced colorectal neoplasia in each group.