Sample Size
AOM
Due to social distancing measures during the COVID-19 pandemic, the occurrence of AOM decreased. We therefore recalculated the sample size during the study to ensure statistical power. We assumed that the proportion of children in the control group with at least 1 episode of AOM would decrease from 30% to 12% within 6 months because pediatric emergency department visits were reduced by approximately 60% in Finland during the COVID-19 pandemic.