Background
infection, deaths, viral infections
HEPATITIS B, VIRUS, VIRAL INFECTION, INFECTION, CHRONIC HEPATITIS, CHB
Chronic hepatitis caused by hepatitis B virus (HBV) infection is a major global health problem, with an estimated 0.6–1 million deaths per year [Developing drugs targeting different HBV life cycle steps has become a critical approach for treating viral infections, such as CHB [HBV core protein-targeting antivirals (CpTAs) are HBc-targeting small molecule compounds [Distinguished from the abovementioned CAM-A and CAM-E CpTAs, Canocapavir is a novel CAM-E CpTA with a pyrazole structure and a new binding site in the HBc [