Safety
sore throat, leukocytosis, anemia, epistaxis
SORE THROAT, ADVERSE REACTIONS, ALEUKOCYTOSIS, ADVERSE EVENTS, ANEMIA, EPISTAXIS
During the whole study period, both ezetimibe tablet and Ezetrol® showed good tolerance. In In the study of fasting condition, a total of 8 volunteers increasing in urinary red blood cells, leukocyte, and neutrophil, sore throat, and epistaxis were observed in 15 times AEs tests. These adverse reactions were considered to be related with the study drugs. In the study of fed condition, 3 volunteers increasing in urine leukocytosis and anemia were detected in 3 times AEs. None of them were judged as serious adverse events (SAEs).