Author contributions
ATM
JHK and SCK conceptualized the study and designed the experiments. DH performed immunofluorescence and immunohistochemistry imaging experiments and analyzed the resulting data. AYL conducted experiments using flow cytometry and analyzed the data. TK and DYK analyzed bioinformatics data. HK, HBD, RP, and ATM performed experiment using highly multiplex imaging. CK, KP, and HK analyzed multiplex imaging data. JHK, JYC, MYC, and AS recruited participants and collected samples. JYC contributed to clinical data analysis. TGK, JHS, and HJK provided experimental support. ECS, MK, and EJC acquired funding for the project. DH, JHK, AYL, and TK prepared the figures and tables. JHK, DH, and AYL wrote and edited the manuscript.