Recruiting patients
prostate, diabetes
PROSTATE, ACUTE BACTERIAL PROSTATITIS, BENIGN PROSTATIC HYPERPLASIA (BPH), HIGH BLOOD PRESSURE, PROSTATE CANCER, DIABETES
From January 2016 to December 2022, 800 patients who underwent transrectal prostate puncture guided by transrectal ultrasonography (TRUS) (12 + X core, all patients underwent preoperative magnetic resonance imaging (MRI) of the prostate, followed by 12-core systematic biopsy with or without targeted biopsy based on the MRI results) in the department of urinary surgery of Foshan Hospital of Traditional Chinese Medicine were recruited. All prostate biopsies were conducted by urologists with more than ten years of working experience in our department. The indications for prostate biopsy were the following: (1) tPSA > 10.0 ng/ml. (2) tPSA > 4.0ng/ml and < 10.0ng/ml with suspicious fPSA/tPSA < 0.16. (3) Affirmative outcomes identified through a DRE for any level of tPSA, and (4) positive findings from imaging techniques like TRUS and MRI have been observed regardless of the level of tPSA. The exclusion criteria were as detailed below: (1) 20 patients previously treated with prostate surgery or previously diagnosed with prostate cancer. (2) 43 patients who received 5 alpha-reductase inhibitors or who had urethral catheters in place, or who had previously undergone invasive therapy for benign prostatic hyperplasia (BPH). (3) 32 patients with acute bacterial prostatitis or other inflammatory systemic illnesses. (4) 54 patients without complete clinical data. (5) 103 patients with high blood pressure, diabetes, or taking lipid-lowering drugs, these patients may have taken lipid-lowering medication in the past or currently. 548 cases were included eventually. The study received official approval from the ethics committee of Foshan Hospital of Traditional Chinese Medicine (20220520). Before transrectal ultrasound-guided prostate puncture, all patients provided informed consent.