Author contribution
RECRUITMENT
Contribution: M.K. designed the study, analyzed the data, and wrote the manuscript. A.M. designed the study and revised and approved the manuscript. S.T., H.S., T.I., E.Y., M.K., K.I., M.S., and M.M. performed recruitment and treatment of patients and opined on the manuscript. H.M. performed experiments and opined on the manuscript. M.O. revised the manuscript. T.T. supervised and revised the manuscript. T.K. designed and supervised the study and approved the manuscript. All authors read and approved the final manuscript.