Results
A total of 150 participants were randomized to simvastatin (n = 77; median [IQR] age, 40 [30-45] years; 43 [56%] female and 34 [44%] male) or placebo (n = 73; median [IQR] age, 35 [31-41] years; 40 [55%] female and 33 [45%] male). Of the 150 participants included in the intention-to-treat analysis, at the end of the study, 8 (5%) withdrew (3 randomized to simvastatin and 5 to placebo) and 6 (4%) were unavailable for follow-up. 