Subgroup analysis
DKA diabetic ketoacidosis, DKA
REGRESSION, RECRUITMENT
Results from logistic regression models revealed that participants receiving saxagliptin plus vitamin D was associated with a 61% reduced risk of significant decrease in the 2-h C-peptide AUC response at 24 months when compared with those in the conventional therapy group (OR = 0.39, 95% CI: 0.20, 0.77; Subgroup Analysis of Responses to Saxagliptin plus Vitamin D. The forest plot presents the odds ratios and their 95% confidence intervals for the changes from baseline through 24 months in the C-peptide AUC (two categories: low versus high, median cut-off point) in the saxagliptin plus vitamin D group as compared with the conventional therapy group, stratified by baseline factors (two categories of each). The logistic regression model was adjusted for age at recruitment, sex, baseline C-peptide (log[AUC + 1]), baseline vitamin D concentration and DKA at diagnosis. Group A: conventional therapy, Group C: saxagliptin plus vitamin D; AUC area under the curve, BMI body mass index, DKA diabetic ketoacidosis