Participant Characteristics at Baseline
cognitive impairment, dementia, motor impairment, comorbid illnesses, Alzheimer Disease Assessment Scale-Cognitive, disability
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); EQ-5D-3L, Euro-Quality of Life–3 Domains–5 Levels.Range, 0 (worst) to 30 (best); scores between 26 and 30 are considered within reference range.Range, 0 (worst) to 30 (best); scores between 24 and 30 are considered within reference range.Represents the number of comorbid illnesses and ranges from 0 (best) to 18 (worst); higher scores are associated with lower physical function.Range, 0 (best) to 60 (worst).Range, 0 (worst) to 100 (best); scores greater than 79 indicate mild motor impairment; 56 to 79, moderate impairment; 36 to 55, severe impairment; and 0 to 35, severe impairment.The Alzheimer Disease Assessment Scale-Cognitive Plus is a measure of cognitive function ranging from −3.46 (best) to 4.31 (worst). Scores of −1 imply healthy cognitive functioning; 0, mild cognitive impairment; and 1, dementia.Range, −0.34 (worst) to 1 (best). The EQ-5D-3L and was used to estimate health utility values.Range, 0 (worst) to 8 (best).Range, 0 (worst) to 12 (best); scores of 9 or less indicate increased risk for disability.