Moderators
VTE
As DOAC pharmacist time is a limited resource in health care systems, moderator analyses will be used to explore the prescriber- and/or patient-characteristics that most benefit from notifications and alerts that facilitate prescriber-pharmacist collaboration. We hypothesize that both alerts and notifications that engage pharmacists will be more effective at improving change in DOACs prescriptions when:• Prescribers (1) are based in primary care vs. medical specialists and/or (2) have prescribed fewer DOACs in the six months preceding randomization; and• Patients (1) are aged 70+; (2) have a VTE (as opposed to AF) diagnosis, as the former has more complex dosing with which many clinicians have less familiarity; (3) have 5+ concurrent medication prescriptions; and/or (4) have moderate or worse renal function (creatinine clearance ≤ 60 ml/min).Moderators will be assessed by adding interaction effects between indicators for alerts/notifications and the moderator(s) of interest to the analysis models described in aims 1 and 2 above. All moderators will be examined individually initially and all tested moderators will be reported. Those that show both clinical and statistical significance will be considered for use in tailoring alert delivery. Exploratory analyses will be reported using 95% confidence intervals.