Statistical Analysis
PROM, cancer, tumor
CANCER, TUMOR
PROMs were scored according to standardized instruments and established precedent.For each PROM, scores were summarized at each time point using descriptive statistics. Linear mixed-effects models were applied to evaluate longitudinal changes in scores, taking intrapatient correlation into account. Univariate models were used to assess associations between PROs and time as well as demographic, tumor, and treatment characteristics. Covariates included PRO time point (baseline, 6 months, 12 months, and 36 months), age at diagnosis (continuous variable), race, ethnicity, cancer subtype (hormone–receptor positive/For each PRO score, a multivariable linear mixed-effects model was developed including PRO time point and all covariates with 