Introduction
hypomenorrhea, infertility
PROLIFERATION, HYPOMENORRHEA, FEMALE INFERTILITY, PROLIFERATION
In recent years, the incidence of female infertility has significantly increased due to various factors. It is reported that approximately 8%–12% of couples worldwide and 15% of couples in China are affected by infertility (The appropriate endometrium thickness (EMT) is an important single etiology of possible infertility (Proliferation of the endometrium depends on the secretion of estrogen under normal physiological conditions. Hence, there is no doubt that estrogen supplementation is the first choice for thin endometrium infertility. In most cases, estrogen supplementation can actually promote endometrium proliferation, i.e., increase EMT and consequently improve the clinical pregnancy rate (As the exclusive tribute medicine for the imperial palace of the Qing Dynasty, the effectiveness of Dingkun pill (DKP) on hypomenorrhea and female infertility has been repeatedly verified in China (