Introduction
head and neck cancers, NPC, carcinoma, Epstein-Barr virus, infection
NASOPHARYNGEAL CARCINOMA, CARCINOMA, INFECTION, HEAD AND NECK CANCER
Nasopharyngeal carcinoma (NPC) is an uncommon epithelial carcinoma and has characteristics distinct from those of other epithelial head and neck cancers. Globally, NPC shows an unbalanced geographic distribution and the non-keratinizing subtype of NPC, which is associated with Epstein-Barr virus (EBV) infection, is predominant in EBV-endemic areasPositron emission tomography/computed tomography (PET/CT) with Intratumoral heterogeneity (ITH) implies subclonal cell variability in time and space, and involves genetic, epigenetic, and metabolic featuresIn this study, we assessed the prognostic value of radiomic features identified in pre- and post-radiotherapy FDG PET images among patients with NPC.