Phase 1b/2
dermatitis acneiform
DISEASE
A total of 50 patients were enrolled in the CRC cohort in phase 1b/2. All patients had received at least two prior lines of therapy and 27 (54%) had > 2 metastatic sites of disease (Table Among patients who received the RP2D in the efficacy-evaluable population (All 50 patients treated at the RP2D experienced a TEAE of any grade, with grade ≥ 3 TEAEs occurring in 68% (The most common TEAEs of any grade included dermatitis acneiform (