2.1. Trial Design
Obesity, MetS
OBESITY, SEVERE OBESITY
In the present randomized controlled clinical trial, female patients were enrolled who presented a clinical diagnosis of severe obesity with or without MetS, and also who were indicated for bariatric surgery. To perform this study, the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) [Obesity was classified according to the WHO established criteria that define BMI as body weight in kilograms divided by the square of the patient’s height in meters (kg/m