MRI acquisition
A crossover design was used to study the effects of psilocybin on brain connectivity in ADE and control rats. Specifically, at the age of 62–68 weeks, all rats underwent two scanning sessions in a randomized order: One with psilocybin (1 mg/kg bodyweight, s.c. [The MRI experiments were conducted at a 9.4 T MR-scanner (Bruker BioSpec, Ettlingen, Germany) with a cryogenically-cooled rat brain coil (four-channel phased array MRI CryoProbe