Conclusion
migraine, cutaneous allodynia, Allodynia, allodynia
MIGRAINE
This study shows that self-reported cutaneous allodynia, an important marker for central sensitization, can potentially be used as a predictor for response to withdrawal therapy in patient with chronic migraine and medication overuse. Allodynia might be an important predictor for treatment response in chronic migraine in general. Furthermore, considering subtypes of cutaneous allodynia, especially extracephalic allodynia and mechanical allodynia, might enhance the predictive value for migraine-related outcomes and may help to increase insight in the mechanisms of chronification in migraine.