2.1. Study Design
PJI
PERIPROSTHETIC HIP JOINT INFECTION
The study was designed as non-randomized, prospective, open-label, with historical control in patients with deep periprosthetic hip joint infection. The study was based on comparing the outcomes of two PJI treatment variants: using etiotropic systemic and local antibiotic therapy (CG; historical control), and systemic antibiotic and local phage combination therapy (SG; prospectively recruited), with a commercial staphylococcal bacteriophage preparation pre-selected according to the pathogen susceptibility.