Comparisons with other studies
PAD
PAD
The primary analysis suggests NMES has no additional benefit overall in individuals with IC receiving local standard care. This finding is divergent from the RCT by Babber Compliance with intervention is an important consideration when managing patients with PAD. In this trial, 69.7 per cent of patients with access to SET met the definition of compliance (50 per cent or more classes held by the site). Current data on patient adherence to SET programmes is problematic due to differences in defining compliance among studies and the large variation in SET programme duration. Harwood Compliance with NMES in this study was 73.9 per cent, which was less than what was observed in the 6-week pilot study (97 per cent) and subsequent RCT (96 per cent)A sensitivity analysis, using only the compliance rules for SET and NMES, with all patients receiving exercise advice, showed no clear statistical differences to the main analysis (including all seven subgroup analyses).