Introduction
deaths
CORONAVIRUS, COVID-19 (CORONAVIRUS DISEASE 2019), SEVERE ACUTE RESPIRATORY SYNDROME
The Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is profoundly affecting life around the world. Globally, as of 25 October 2022, there have been more than 0.6 billion confirmed cases of COVID-19, including nearly 6.5 million deaths, and the number of cases continues to rise. Safe and effective vaccination strategies are urgently needed to control the COVID-19 pandemic [The emergence and rapid spread of SARS-CoV-2 variants of concern and waning immunity over time are challenging the effectiveness of vaccines [In our previously reported study [