Study design and participants
allergic, pneumonia, hematologic, hepatic, and kidney function, lung cancer, Cancer
ESOPHAGEAL CANCER, SYSTEMIC DISEASE, PNEUMONIA, BREAST CANCER, LUNG CANCER, ONCOLOGY, DISEASES, CANCER
Our research team prospectively conducted this research at department of thoracic radiotherapy of Shandong Cancer Hospital and Institute in Shandong Province, China. The inclusion criteria included: (1) patients 18 years or older; (2) patients with histologically confirmed breast cancer, lung cancer or esophageal cancer. (3) Patients received definitive radiation therapy in which the target included supraclavicular area. (4) Eastern Cooperative Oncology Group performance status of 0–1. 5. Adequate hematologic, hepatic, and kidney function profile. (5) Chemotherapy, targeted therapy and endocrine therapy are allowed.Exclusion criteria included: (1) patients with unhealed wounds in the radiation area. (2) Patient has severe uncontrolled systemic diseases, such as acute circulatory diseases; severe pneumonia, etc. (3) Women of childbearing age need to exclude pregnancy or lactation. (4) The patient is allergic to EGCG-related components.This study has been approved by the Ethics Committee of our research center (Shandong First Medical University Affiliated Cancer Hospital). Informed consent was obtained from all patients and/or their legal guardian(s). All methods were performed in accordance with the relevant guidelines and regulations.