Authors’ contributions
GT participated in conceptualisation, data curation and original draft preparation. SR contributed in conceptualisation, supervision, methodology, writing and reviewing of the manuscript. AK contributed in the conceptualisation and supervision of the research. AB and AM participated in the conceptualisation and histopathology reviews. ED and SAS participated in the radiological staging and response assessment. Su B conceptualised and undertook the palliative intervention and supportive care for the trial patients. Sa B participated in the conceptualisation of the study and surgical interventions required for the trial patients. All authors read and approved the final manuscript.