Resource use and costs
VTE
Resource use was collected prospectively in the electronic Case Record Form (eCRF) developed for the MODIGLIA-NI trial on the Cleanweb™ ® software, completed at the initial ED visit and for all hospitalizations at a three-months horizon. During the initial ED visit, data related to laboratory tests including D-dimer use, CTPA use, ventilation–perfusion [V̇/Q̇] scan use, and technical charges (for equipment and maintenance) were collected. The total length of stay of VTE related hospitalizations and discharge information (using the severity adjusted diagnostic related groups or DRGs) were extracted from the hospital information system for the index admission and subsequent admissions during the three-month follow-up period.The cost of laboratory tests was estimated from the French national tariffs of D-dimer testing, CTPA, [V̇/Q̇] scan and technical charges (Table 