Blood and urine samples
BLOOD
Blood and urine samples were collected the evening of day 7 and the morning of day 8. Urine samples were collected in a plastic container; venous blood samples were obtained via venipuncture into 1 × 10 ml vacutainer for serum and 1 × 10 ml vacutainer coated with EDTA to obtain plasma. The EDTA vacutainer was immediately centrifuged at 3000 ×Samples were analysed for high sensitivity c-reactive protein (hs-CRP), interleukin-6 (IL-6), cortisol, and urine samples for normetanephrine, as these are sensitive to changes in sleep quality [