Design of the study and participants
T2D, microalbuminuria, nephropathy
MYOCARDIAL INFARCTION, STROKE, COMPLICATIONS, NEPHROPATHY, TRANSIENT ISCHEMIC ATTACK
This double-blind, randomized, placebo-controlled clinical trial was performed on 92 patients with T2D and nephropathy that referred to the Isfahan Endocrine and Metabolism Research Center from November 2019 to April 2021.Inclusion criteria consisted of T2D patients age ≥ 18 years, and microalbuminuria (urine albuminFurthermore, patients who were taking short-acting insulins, rosiglitazone, pioglitazone, GLP-1 receptor analogues, sodium glucose co-transporter 2 inhibitors or anti-obesity drugs within three months before the beginning of the study, those with a history of myocardial infarction, stroke, or transient ischemic attack within 6 months of the beginning of the study, patients who had non-diabetic renal failure or urinary tract infection, or those who had received a kidney transplant were not included in the study. They were excluded the study, in the case of not cooperating, not attending in the follow-up sessions, or showing drug-induced complications.