Outcome measures
upper-extremity impairment
ADVERSE EVENTS, SECONDARY
The primary end point was safety as measured by the incidence of serious adverse events during study participation. Among the secondary measures, the first motor outcome metric for characterization of the effects of the investigative treatment on upper-extremity impairment was the FM-UE, as it was the measure that determined the participant’s eligibility for the study under the inclusion and exclusion criteria. Additional secondary measures included indices of distal motor FA and quality of life as well as metabolic changes characterized by 