Introduction
Postoperative pancreatic fistula, PD, POPF
PATHOLOGY, SEQUELAE
Postoperative pancreatic fistula (POPF) is a common condition with incidences ranging from 13 to 41 per cent, and remains the most important and challenging determinant of postoperative morbidity and mortality after pancreatoduodenectomy (PD)Identifying patients at risk of having POPF, as well as predicting its development, may be crucial for preventing the incidence of severe sequelae. Different factors have been considered to influence the development of POPF, including soft pancreas, small main pancreatic duct diameter, high-risk pathology, and excessive blood lossDespite improvements in perioperative management and surgical techniques, aiming to decrease the incidence of POPF formation through the use of somatostatin analogues, pancreatic stents, minimally invasive surgery, reinforcement of the anastomosis with glue, autologous tissues, non-autologous absorbable or non-absorbable materials, no differences in POPF rates have been reported over the last decadeAmong the different approaches for preventing the onset of POPF, the use of sealants has emerged as a promising strategyThe purpose of this study was to evaluate the impact of a PEG-coated haemostatic patch on the incidence rate of CR-POPF after PD according to the International Study Group of Pancreatic Surgery (ISGPS) criteria