Authors’ contributions
S.Y., N.K., W.W., K.S., M.K., Y.T., and R.M. conceived the study concept and design. M.K., Y.T., and R.M. as principal investigator was responsible for study logistics, data acquisition. Y.S. and N.K. prepared the manuscript. S.Y., N.K., K.S., Y.T., and Y.I. were responsible for conducting the trial, and data collection. S.Y., N.K., Y.T., and R.M. carried out the statistical analysis. Y.I. contributed to the test as clinical investigator. Y.M. and M.S. supervised the study design and commented on the manuscript. All authors reviewed the manuscript.