Participants
SARS-CoV-2 infection, dyspnea, respiratory illness, hepatic failure, cough, hypersensitivity
MYASTHENIA GRAVIS, HYPERSENSITIVITY, SARS-COV-2 INFECTION, HEPATIC FAILURE
We enrolled adult symptomatic patients with a proven diagnosis of COVID-19 who had been admitted to hospital within the last 24h. The following inclusion criteria had to be met: able to give informed consent, age ≥40 and <90 years, SARS-CoV-2 infection demonstrated by PCR, typical symptoms of COVID-19 (new onset or exacerbation of a pre-existing cough due to a chronic respiratory illness, dyspnea, increased body temperature (axillary T° > 37.6°C or oral T°>38°C), and admission to hospital within 10 days of onset of symptoms. Exclusion criteria were: hypersensitivity to doxycycline; myasthenia gravis, pregnancy, and hepatic failure (CHILD-Pugh score C).