Changes in metabolic syndrome
INSULIN RESISTANCE
The MetS-Z decreased by 0.52 to 0.06, P < 0.001, during the low-calorie diet (Table One year after the low-calorie diet, the MetS-Z was unchanged in the placebo and exercise groups (Table Adjusting for blood pressure or lipid-lowering medication, smoking, and alcohol consumption at inclusion did not affect the analysis results (Additional file The reduced insulin resistance seen during low-calorie was maintained in the adherent exercise groups, while insulin resistance increased in the placebo and liraglutide groups (Table 