Re-evaluation of pathology
NEC
PATHOLOGY, NEUROENDOCRINE CARCINOMA
At the time of protocol development (2014) and study enrolment (2014-2017), all GEP-NEN with a Ki-67 > 20% were classified as neuroendocrine carcinoma, NEC G3. The 2019 WHO pathology grading system divides HG GEP-NEN into the well-differentiated NET G3 and the poorly differentiated NEC [