Subject baseline characteristics and demographics
PWS, SD
DELETION
A total of 16 (45.7%) male and 19 (54.3%) female subjects received treatment; 22 (63.9%) had paternal deletion, 10 (28.6%) had aberrant methylation (mUPD and imprinting defect), and three with unknown genotype. The three patients with unknown genotype were diagnosed with PWS using methylation-specific polymerase chain reaction; however, specific genetic aberrations were not distinguishable with this method. There were 20 (57.1%) and 15 (42.9%) subjects in the < 9 months and ≥ 9 months groups, respectively; statistical significances between the < 9 months and ≥ 9 months groups were observed in chronological age at baseline, chronological age at rhGH initiation, height, weight, head circumference, BMI, TMQ, FMQ, and GMQ (Table Patient demographics and baseline characteristics of the full analysis setData are presented as mean ± SD or as 