Epigenetic and inflammatory markers
Tumor Necrosis, TNF-α
At baseline (T0) and post-treatment (T2), 3 tubes of blood (16 ml) are drawn in all consenting participants to perform future analyses on epigenetic and inflammatory markers underlying the effects of TFT. The inflammatory markers C-reactive protein (CRP), Tumor Necrosis Factor-alpha (TNF-α) and Interleukin-6 (IL-6) will be examined. The DNA that will be extracted from the blood will be used for future exploratory epigenetic research. Epigenetic changes will be analyzed using microarrays, rather than specific genes.