Conclusions
pain
Together, these findings suggest that 10 g/d of CP supplementation may be superior to a larger dose of 20 g/d, but both doses are better than nothing at all in improving physical function/ADLs, pain, mental component scores, and physical component scores in those supplementing for at least 6 months. Additionally, females may see improvements at higher doses than males, and higher frequency exercisers may experience enhanced benefits compared to their more sedentary counterparts. Finally, declines in quality of life (QOL) were observed over 6 months of supplementation in more sedentary participants in the 10 g/d and placebo groups, but declines were not as large in participants taking 20 g/d of CP, suggesting a larger dose may be needed to protect against declines in QOL over time. Further, as evidenced by our data, the effects of collagen supplementation may be outcome, time, dose, and population dependent.