Adverse event
PRS
Three patients on the PRS regimen were excluded from safety analysis because consent was withdrawn before starting treatment (Safety analysis in all randomized patients receiving at least one dose of the trial medication.Notes: All data were presented as number (percentage) unless specified. PRS: Parabolic Response Surface; ALT: alanine aminotransferase; AST: aspartate aminotransferase; TBIL: total bilirubin; UA: uric acid; ULN: upper limit of normal; NA: not applicable.