Results
Of the 4480 women (POAI (n = 2976); control (n = 1504)) who entered POETIC, Ki67Consort diagram of available samples. Fewer surgical samples from control patients were analysed because little extra value was expected from multiple samples in the absence of treatment. A subset of one-third of control patients were selected at random for analysis, while all patients in the treatment group were analysed; this led to 7/9 samples from the whole trial being analysed