Trial Design and Oversight
This was a multicenter randomized clinical trial with parallel-group design (1:1). Patients were stratified according to treating institution. We evaluated the intraoperative use of irrigation fluid at body temperature (37 °C, BT group) vs room temperature (22 °C, RT group) in burr hole evacuation of cSDH. The study protocol has previously been published in addition to the registration at ClinicalTrials.org (