Outcome
SECONDARY
This study evaluated changes in myocardial contractility after Esmolol lowered heart rate mainly using GLS, and selected the values of GLS at 48 h after admission, when, the heart rate reached target heart rate after using Esmolol, becoming the prime outcome. Daily dosage of norepinephrine, ratio of reaching target heart rate, values of GEF and dP/dtmax, length of ICU and in-hospital, duration of mechanical ventilation and follow-up records of 28d and 90d were considered secondary outcomes.