Discussion
PND
In this study, no significant changes in our primary outcomes, inflammatory serum markers or HRV-measures, were found.However, in line with the results from the main study, participants randomized to MBCP reported a significantly larger reduction in perceived stress and a significantly larger increase in mindfulness, compared to participants randomized to Lamaze. The finding of significant differences between groups in reductions in PND [This study is the first one to compare the effects of MBCP with an active control group not only on psychological outcomes, but also on physiological outcomes. The lack of significant effects of MBCP on inflammatory serum markers and HRV parameters found in this study are in line with the results reported in a recent review and meta-analysis [A normal pregnancy is related to remarkable changes in the immune system. Complex adaptations are made to protect the fetus against pathogens as well as to adjust the mother´s immunological response in order to prevent rejection of the fetus [The findings on larger reduction in perceived stress and larger increase in mindfulness in the MBCP group compared to the Lamaze group, are in line with previous findings [