Sensitivity analysis
The one-way sensitivity analysis was conducted to ensure the robustness of the results. A threshold analysis of the maximum tolerable cost of PGT-A was carried out, which would still provide the same cost per live birth as the conventional-IVF group. In addition, the theoretical threshold for the clinical pregnancy rate to achieve the cost-effectiveness of PGT-A was estimated. One-way sensitivity analysis was performed by changing a parameter every time to the highest or lowest values. The expenditures were set to fluctuate between − 25% and + 25%. The theoretical necessary thresholds for the maximum cost of PGT-A and the clinical pregnancy rate to achieve cost-effectiveness of PGT-A were also estimated. The cost of PGT-A varied in the range of ¥0–10 000. A Tornado graph was used to show the influential variables and the results of one-way sensitivity.The probabilistic sensitivity analysis was conducted by varying all parameters within a set of different distributions simultaneously in 1000 Monte Carlo simulation iterations to illustrate the results of uncertain analysis and build a cost-effectiveness acceptability curve [