Materials and methods
wart, atopic dermatitis, HIV and diabetes
DISORDER, WART, ATOPIC DERMATITIS, RECRUITMENT, WARTS, WARTS, ALLERGIC DISORDERS
This study was conducted between July 2019 and June 2020 at the outpatient clinic of the dermatology department of Badr University Hospital, Helwan University. The study protocol was approved by the Faculty of Medicine, Helwan University Research Ethics Committee. All the participants received full information prior to enrollment and an informed consent was obtained. Fifty patients were recruited, either with recalcitrant or non-recalcitrant warts. Warts were considered recalcitrant, when they failed to clear following treatment with two or more different modalities. We excluded patients receiving any immune-altering drugs (e.g., systemic steroids, chemotherapy) as well as those with a history of any disorder affecting their immune system, e.g., HIV and diabetes, pregnant and lactating females, patients with atopic dermatitis or history of other allergic disorders, and patients with history of wart treatment within 12 weeks prior to enrollment were also excluded.During the first visit following recruitment, full history was obtained, thorough clinical examination was performed, and warts’ lesions were photographed with detailed data documentation. Participants were randomly assigned to group A or B using the sealed envelope technique.