Baseline (D0) weight and BMI influence peak serum (25W) MPA and NET concentrations after excluding non-study progestins at D0 and 25W in PP2 subgroup.
overweight
Graphs indicate D0 weight (kg) (A & B) or D0 BMI (C & D) plotted against 25W serum concentrations of MPA (nM) (A & C) or NET (nM) (B & D) in the DMPA-IM or NET-EN arm, respectively, for each individual. Non-parametric Spearman correlation analysis was performed (A–D). For (C & D) Kruskal-Wallis with Dunn’s multiple comparison test was performed to compare 25W peak serum concentrations in normal weight women to those in other weight categories. Significant differences are indicated by asterisks where * and *** represent p<0.05 and p<0.001, respectively. Under—underweight; Over—overweight.