Comparison with the literature
diabetes and renal disease, stroke, hypertensive, carotid artery disease, PVD
ADVERSE EVENTS, STROKE, CARDIAC EVENTS, PVD, CAROTID ARTERY DISEASE, EVENTS
The results that nondipping is a risk factor for adverse prognosis in patients with PVD is in line with studies in hypertensive patients and in the general population, as well as in patients in hemodialysis.The prevalence of nondipping is higher in high-risk cohorts; for example, in patients with diabetes and renal disease. As expected, the prevalence of nondipping was markedly higher (43%) in our cohort compared to a general hypertensive population (25%).Smoking is a particularly strong risk factor for PVD, and a higher proportion of the participants in this study were smokers than the general population in Sweden.Interestingly, nondipping was associated considerably stronger with incident adverse events in our subgroup with carotid artery disease than in the subgroup with abnormal ABI. Previous data suggest that the ABPM nondipping pattern is more strongly associated with incident stroke events than with cardiac events.