Authors' Contributions
NDKD, nondiabetic kidney disease, diabetic nephropathy
REGRESSION, HYPERURICEMIA, TYPE 2 DIABETES, DIABETIC NEPHROPATHY
Junqing Zhang contributed to the study's conception and design. All authors contributed to the material preparation and data collection. Yuetong Zhao contributed to the data analysis. The first draft of the manuscript was written by Yuetong Zhao, and all authors commented on previous versions of the manuscript. All authors reviewed the manuscript and approved the final version for submission. Junqing Zhang is the guarantor of this work and, as such, had full access to all data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.Flow chart of the patient enrollment process. PKUFH: Peking University First Hospital; PKUPH: Peking University People's Hospital; PKUTH: Peking University Third Hospital; PKUIH: Peking University International Hospital; T2D: type 2 diabetes; DN: diabetic nephropathy; iDN: isolated diabetic nephropathy; NDKD: nondiabetic kidney disease.The ROC curves in each group. (a) ROC of the training group based on 202 patients, AUC = 0.860, 95% CI (0.810-0.910); (b) ROC of the internal validation group based on 87 patients, AUC = 0.924, 95% CI (0.871-0.976); (c) ROC of the external validation group based on 373 patients, AUC = 0.855, 95% CI (0.814-0.895); sixteen patients were included in the missing item because of incomplete data; (d) ROC of 662 patients, AUC = 0.863, 95% CI (0.836-0.891).Basic characteristics of patients enrolled in all subcenters.Data are presented as percentages for categorical data, averages (Univariate logistic regression analysis and multivariate logistic regression analysis of DN in the training group.High urea nitrogen: >7.1 mmol/l; hyperuricemia: uric acid >360 Multivariate logistic regression analysis of risk factors for DN in the training group and diabetic nephropathy risk score model.Proportion of DN patients in different risk groups.