Authors’ contributions
Qi Tan, Zhaomei Cui and Jun Wang designed the study concept. All authors developed the study design and protocol. Data collection and preparation was performed by Yingying Ma and Na Li. Analysis was performed by Yuanyuan Yu and Anbiao Wang. Zhaomei Cui and Na Li prepared all the figures. The manuscript was written by Qi Tan. All co-authors provided input and critical review of the manuscript leading to the final version. All authors read and approved the final manuscript.