Background
PONV
OBESE
Laparoscopic bariatric surgery (LBS) has been generally recognized as a safe and effective procedure for obese adults, given the global prevalence of overweight and obesity [The etiology of PONV is multifactorial involving patient, surgical, and anesthesia-related factors. Several types of neurotransmitters, including serotonin, dopamine, muscarine, neurokinin-1, opioids, and histamine are closely associated with PONV [Considering the potential preventive effects of penehyclidine against PONV, we hypothesized that intravenous infusion of penehyclidine may alleviate PONV and improve postoperative recovery within the first 48 h in patients scheduled for LBS.