Conclusions
pain
A low initial dose of PSL (15 mg/d) was not inferior to the standard dose of PSL (30 mg/d) in terms of efficacy and showed a similar safety profile. The use of a low initial dose of PSL could be recommended for Chinese adult SAT patients with suboptimal response to NSAIDs or moderate-to-severe pain. Further studies with longer follow-up periods in multiple countries are needed to validate our findings.