Primary outcome: MAKE30 (major adverse kidney events by 30 days)
AKI, Death, Digestive, Diabetes
KIDNEY DISEASES, DIABETES
Because clinical research evaluating the prevention and treatment of AKI has been hampered by the unclear relationship between acute changes in kidney function and longer-term outcomes, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) [Death ORProvision of dialysis ORSustained loss of kidney function (at 30 days) reflected by a 100% [This outcome will be classified following the completion of data extraction and the 30-day follow-up assessment (time 0, as defined above, is used to calculate the 30-day interval). It will be adjudicated based on laboratory values, chart documentation, and 30-day laboratory results. As baseline creatinine values are rarely available for children, all participants will be assigned a value which will be calculated employing a standardized baseline glomerular filtration rate (GFR = 120 ml/min/1.73m