Outcome variables
Defect
ADVERSE EVENTS, ADVERSE EVENT, EVENTS, LEAKAGE
The primary outcome variable was successful defect closure by EVT, with or without the use of other endoscopic treatment modalities. Defect closure was determined by presence of at least two of the following criteria:endoscopic inspection: no remaining visible defect after treatment;imaging: no remaining contrast leakage on CT scan;oral intake: tolerance of oral intake after EVT.
Secondary outcome variables included success rate without the need for additional (non-)endoscopic treatment modalities, treatment characteristics, adverse events, incidents, and all-cause mortality, including in-hospital and 30-day mortality. Treatment characteristics were defined as outcomes specifically related to the EVT treatment, including treatment technique, number of sponge exchanges, and treatment duration. Adverse events were defined as any events interfering with the scheduled treatment
