Participants
SARS-CoV-2 infection, heart disease, allergy, prolonged QT syndrome, liver or kidney failure
ALLERGY, SARS-COV-2 INFECTION, HEART DISEASE
We recruited participants from four public hospitals in Lima Metropolitan Area in Peru; each study site had a designated area for all study procedures. Adult healthcare workers, without evidence of SARS-CoV-2 infection (negative PCR at enrolment), working in hospital services (triage, emergency department, hospitalisation, ICU, etc.) with direct contact with patients with COVID-19 were eligible to participate. Exclusion criteria included previous (last 30 days) or current use of hydroxychloroquine, chloroquine sulfate, or azithromycin; known allergy or intolerance to hydroxychloroquine and/or chloroquine, a history of heart disease or a known history of prolonged QT syndrome; other conditions, such as Glucose-6-phosphate dehydrogenase (G6PD) deficiency, liver or kidney failure or, presence of alterations in visual acuity or field, which made participation in the study not the most benefitial for the individual.