Statistical analyses
REMISSION
One-way analysis of variance (ANOVA) and χFor categorical data, analyses of response, remission, and relapse rates were conducted for both the per protocol (PP) and ITT sample to ensure robustness of the results. For the PP sample, χLinear-mixed models were performed with the packages ‘lme4’, ‘lmerTest’, and ‘emmeans’ in R (version 4.0.2). Multiple imputation was performed with the package ‘mice’ in R (version 4.0.2). Other statistical analyses were conducted in SPSS (version 24.0).