Compliance
weight gain, nausea, fatigue, constipation
ADVERSE EFFECTS
Probiotics were well tolerated, and the patients reported no serious adverse effects or were recognized by the physicians. Compliance was high (greater than 95%). Of the 40 patients who completed the 4-month trial, the most common adverse effects included constipation (12.5%), weight gain (12.5%), nausea (10.0%), and worsened fatigue (5%). No patients showed evidence of MS relapse.