4.8. Implantation of Matrilin-3 Primed ASC Spheroids in Combination with HA
LBP, medial branch block
DEGENERATION
Intervertebral disc displaying signs of chronic LBP and confirmed IVD degeneration through T2-weighted MRI were chosen for implantation with a combination of matrilin-3 primed ASC spheroids and HA. Our selection relied on radiographic data and pain-blocking methods, such as the medial branch block. For the cell injection, patients were placed in a prone position. The injection site was anesthetized using 1% buffered lidocaine. The matrilin-3 primed ASC spheroids (1.0 × 10