DTI Changes With Strict BP Control
Fractional anisotropy is indicative of the direction of the diffusion of water molecules, while MD describes the rotationally invariant magnitude of the diffusion. Higher FA values are typically observed in heavily myelinated WM tracts,Changes in FA and, to a lesser extent, MD, generally aligned with WML findings, with strict BP control associated with smaller decreases in FA and smaller increases in MD over time with intensive treatment. The PRESERVE study