Conclusions
sleep dependence of motor learning, upper limb impairments
Additional AO + MI-training benefits in terms of manual dexterity were found when the training sessions were followed by immediate sleep. These findings proved a sleep dependence of motor learning induced by AO + MI-training and may be crucial in patients with upper limb impairments, where conventional rehabilitation delivered in association with AO + MI-training followed by early sleep may facilitate motor and functional recovery.