Assessment of eligibility
hypoglycemia, renal impairment, T2DM, pancreatitis
DIABETIC KETOACIDOSIS, HYPERSENSITIVITY REACTIONS, RENAL IMPAIRMENT, TYPE 1 DIABETES, HYPOGLYCEMIA, PANCREATITIS
A non-probability consecutive sampling method was used to screen patients per study eligibility criteria. The inclusion criteria for the trial were both gender (Pakistan nationals) with T2DM, between ages 18 to 65 years, HbA1c between 7 − 10%, and patients uncontrolled on Metformin and lifestyle modification for at least 3 months. However, patients with type 1 diabetes, pregnant or lactating women, ≥ 1 episode of severe hypoglycemia, diabetic ketoacidosis, and/or hyperosmolar hyperglycemic state in the preceding 3 months, history of pancreatitis or patients with any contraindication including severe renal impairment, hypersensitivity reactions with Sitagliptin or Metformin were excluded from the study.