Bacterial species present in the investigational product are detected in the fecal microbiome
The stool samples were analyzed to identify the species present in the multi-strain product. The samples were analyzed at baseline and at the end of the probiotic intervention period (Heatmap and contingency table of detected multi-strain probiotic representatives. Left panel differential abundance species between baseline (Day 0) and end of multi-strain probiotic intervention on Day 56 ( ± 2 days). Species are shown over‐represented (red color) or under‐represented (blue color) in Day 56 respect to Day 0. Right panel, the number of participants in which the probiotic strains abundance was different from zero. Data was analyzed using the Wilcoxon signed-rank test and p-values of < 0.05 were considered significant.