Author contributions
J.S.H., K.-H.W., H.-G.R., H.R.S. and J.S.W. were involved in the design of the overall study and strategy. C.M., I.F. and M.W.L. provided feedback on the study design. C.T., A.N., Y.M., J.B., J.R., M.W., S.M.S., N.H.G., M.M., A.H., B.K., K.L.C., M.L. and S.H. performed the immunogenicity analyses. J.S.H., M.M., T.H., S.M.R., C.M.T., S.U.J., S.H., A.P., E.J. and J.S.W. conducted patient data and sample collection as well as medical evaluation and analysis. J.S.H., M.M., T.H., S.M.R., C.M.T., S.U.J., C.A.P., S.H., T.O.G., E.J., H.R.S. and J.S.W. collected data as study investigators. J.S. performed the in silico peptide binding prediction. S.U.J., C.M. and I.F. developed the statistical design and oversaw the data analysis. M.D., M.R. and M.T.O. conducted GMP production of CoVac-1. J.S.H., C.T., M.M., A.N., H.R.S. and J.S.W. drafted the manuscript. All authors supported the creation of the manuscript by review and editing.