Impact on daily practice
Patients with a significant (Qp:Qs > 1.3) but eccentric iASD (eccentricity index ≥ 1.9) 1 month after M-TEER have a higher closure probability within 6 months in comparison to patients with rounder defects. The geometric characterization of the iASD maybe a viable strategy to improve the timing of treatment (interventional closure vs. watchful waiting).