2.5. Prosthodontic Protocol 
fractures, denture, occlusion, lingualized occlusion
All new mandibular ODs were made by two trained specialists in prosthodontics and were delivered two to three months after the MDI insertions. The procedure was as follows: After obtaining alginate impressions, custom trays were made to obtain custom impressions for each participant. They were made using a thermoplastic border material and an additive low-viscosity silicone. The occlusal rims were made in the laboratory. The vertical jaw dimension of the lower jaw was recorded at the centric jaw relation for each participant and transferred into a semi-adjustable articulator. Semi-anatomical artificial teeth (lingualized occlusion scheme) were set up in the laboratory. After testing a trial denture to verify satisfactory esthetics and antagonistic contacts in the centric relation, new dentures were processed. All mandibular ODs were strengthened with a CoCr metal framework to prevent fractures. One to two days after the OD delivery and trial wearing (without MDI loading), metal housings with O-rings were mounted chairside using blockout shims and a self-curing acrylic resin (GC Reline, GC America Inc., Alsip, IL, USA). The occlusion was again checked and adjusted. During the adaptation period (fifteen days), the oral mucosa was inspected for soreness, and the denture was trimmed off if necessary. 