Study design and setting
TB, AIDS, Kaposi’s Sarcoma
AIDS, OPPORTUNISTIC INFECTIONS, TUBERCULOSIS, EMERGENCY, MALARIA
We conducted an open-label, randomized trial of same-day treatment versus standard care for patients who presented with symptoms of TB at HIV diagnosis at the Haitian Group for the Study of Kaposi’s Sarcoma and Opportunistic Infections (GHESKIO) in Port-au-Prince, Haiti. The primary study endpoint was the proportion of participants in each group who were retained in care with 48-week HIV-1 RNA <200 copies/mL.GHESKIO is a Haitian nongovernmental organization and the largest provider of HIV and TB treatment in the Caribbean. HIV care at GHESKIO is largely funded by the US President’s Emergency Plan for AIDS Relief (PEPFAR) and the Global Fund to Fight AIDS, Tuberculosis, and Malaria. All care is provided free of charge. The adult HIV prevalence in Haiti is an estimated 1.8% and the estimated incidence of TB is 168/100,000 [