Partial regression plot illustrating the relationship between residuals of the natural log transformed plasma concentrations of interleukin (IL)-6 and residualized change in Hamilton Depression Rating Scale (HDRS) score.
hyperthermia, Depression, WBH
The Pearson correlation between the two sets of residuals is equal to the partial correlation between HDRS scores at week 2 post-WBH/sham treatment and the natural log transformed concentration of plasma IL-6 assessed immediately post-WBH/sham treatment (controlling for baseline HDRS scores and baseline natural log transformed concentration of plasma IL-6, respectively). HDRS Hamilton Depression Rating Scale, IL interleukin, WBH whole-body hyperthermia.