Statistical analysis
hypoxia, hypercapnia
REGRESSION, HYPOXIA
As the authors have not found a previous study which evaluated the effect of NHF with air on PtcCOThe analysis population for the main analyses of this study is Full Analysis Set (FAS). FAS was defined as those subjects in the intention-to-treat for whom the efficacy endpoint, transcutaneous COFor efficacy analysis, the authors estimated risk ratios and 95% confidence intervals (CIs) for the occurrence of hypercapnia or marked hypercapnia by modified Poisson regression with body weight as an adjusted variable. In addition, risk differences were calculated by generalized regression analysis using the identity function. For hypoxia, risk ratios and risk differences were calculated without adjustment for body weight from the above model, because estimation was not unstable. The mean difference between the groups for PtcCOAll statistical analyses were carried out using R, version 4.1.2. All 