Study design
The study was a biphasic, randomized, controlled, single-blind dietary intervention. Phase one included a six month intervention that compared two diets targeting glycemic control, while phase two included a six month follow-up period. Eligible participants were invited for a visit at the trial’s site (Weizmann Institute of Science) during which they were informed in detail of all study procedures and requirements. After completion of the run-in stage, participants were randomly assigned in a 1:1 ratio to the PPT or MED diets. Covariate adaptive randomization with minimization was performed to ensure minimal differences between the groups in six prognostic baseline characteristics: age, sex (self-reported), weight, BMI, %HbA1c and fasting plasma glucose (FPG)