Patterns of Changes in the Type III White Matter Parcellation Map–Derived Deep White Matter Regions of Interest When Comparing Intensive Treatment With Standard Treatment 
white matter lesions
A, Changes in white matter lesions. B, Changes in diffusion tensor imaging (DTI) fractional anisotropy. C, Changes in DTI mean diffusivity. The red-yellow color scale indicates effect size; that is, smaller increase over time for intensive treatment compared with standard treatment. The blue-green color scale indicates effect size; that is, larger increase for intensive treatment compared with standard treatment. Changes are significant at 