Development of symptoms
The analysis of sum symptom scores showed that the study population (ITT analysis set) suffered from moderate symptoms (mean values ± SD: 38.58 ± 10.04) on day 1 of the study (supplementary Table Absolute changes of total symptom scores from baseline (day 1) until day 11 of treatment (ITT analysis set).A closer look at single symptoms confirmed moderate expression of symptoms (supplementary Figure 