Cumulative rate of molecular response.
Cumulative rate of Of 53 patients who achieved MMR, 5 lost MMR by data cutoff, while 48 maintained MMR or achieved deeper responses. Of 20 patients who were in MMR at screening, the majority maintained or achieved deeper responses, and only 1 lost MMR by data cutoff. The Kaplan–Meier estimated rate of durable MMR at 96 weeks was 94% (95% CI, 86.4%–100.0%) among patients not in MMR at screening who achieved MMR at any time and 94.4% (95% CI, 84.4%–100%) among patients in MMR at screening. All, except 1 of the 6 patients who lost MMR, received asciminib in the fourth line or later (Supplementary Fig. Sixty-two patients were evaluable (There were 101 and 105 patients who had The Kaplan–Meier estimated EFS rate at 96 weeks was 87% (95% CI, 80%–93%), and median time to EFS was not reached (Fig. 