Alterations in gut microbiota after FMT.
UC
Bacterial α diversity was assessed by determining richness (observed and Chao1), Shannon diversity, and Pielou’s evenness based on 16S V3-V4 sequencing. As expected, the bacterial α diversity, observed richness (Similarly, both richness indices were significantly higher in donor samples than in baseline samples of patients. The bacterial richness of samples from UC patients increased significantly after capsulized FMT and was comparable to that of samples obtained from donors at week 1 but was reduced at weeks 4 and 12 (Alterations in gut bacterial communities of UC patients after FMT. (A) Estimating the α diversity by the richness (observed OTUs and Chao1) and Shannon and Pielou’s evenness. The dashed line indicates significant (