Contribution statement
PAF
CMF contributed to research design, conducted all experiments, acquired and analysed the data and drafted the manuscript. SH, ADM, DJW, AF, GC, PAF and TWJ contributed to research design, analysis of data and revision of the manuscript. RJM contributed to research design, data analysis and drafted the manuscript. All authors approved the final version of the manuscript to be published. RJM is responsible for the integrity of the work as a whole.