Cholesterol measurement
Total cholesterol levels were obtained from frozen plasma samples which were collected at the time of enrollment in the clinical trials. Total cholesterol was measured in the year 2016 for SAILS samples using the Infinity Cholesterol Liquid Stable Reagent (TR2242, from ThermoFisher), and the Amplex Red Cholesterol Assay (A12216, from ThermoFisher) was used for HARP-2 samples in 2020.