Ethics approval and consent to participate
This study was approved by the Institution Review Board (Ethics Commission of Children’s Hospital of Shanghai, Ref. No. 2021R029-F02; registered at the China Clinical Trial Registry Center, registration number ChiCTR2200066131), in accordance with the ethical guidelines of the Declaration of Helsinki. Written informed consent was obtained from the parents or relatives of patients. We confirm that all methods were performed in accordance with the relevant guidelines and regulations.