Background
Tooth, tooth
Tooth extraction is one of the most common procedures performed in dental clinics. Although immediate implant placement has become popular following tooth extraction, it is not indicated in all cases and does not prevent physiological bone resorption and soft tissue alterations [Platelet-rich fibrin (PRF) is apart from natural blood product that’s produced after blood centrifugation. It contains concentrated platelets, growth factors, and cytokines [Concentrated platelet-rich fibrin (C-PRF) is the last generation of liquid-form PRF. It is mainly used in dermatology and bone augmentation procedures. While the use of C-PRF in bone regeneration is usually done once during the surgical phase, it is recommended to be used many times for skin and hair regeneration [Although A-PRF + has many clinical benefits, its effectiveness diminishes over a period of two weeks as it is resorbed and loses its biological activities [