CONCLUSIONS
ADVERSE EVENTS
Self-management of blood pressure including home blood pressure monitoring, educational components, and patients’ self-titration of antihypertensive medication based on an individualized pre-arranged plan in the primary care setting may be a promising strategy for reducing blood pressure compared to usual care at 12 months of follow-up, without increasing healthcare utilization or adverse events. Our results suggest that, in the context of routine clinical practice, high-level patient empowerment strategies based on self-adjustment of antihypertensive treatments, with a pre-agreed plan and, without the need of additional medical visits (except in specific cases), the involvement of health professionals or health coaches, or the use of additional resources, may have relevant potential implications for both primary care practice and the health system as a whole.