Study design
SECONDARY, CORTEX
Double-blind, randomized, placebo-controlled feasibility study with four parallel intervention arms (Fig. Study design and timelines. ISF-NF: infraslow frequency neurofeedback, pgACC: pregenual anterior cingulate cortex, dACC: dorsal anterior cingulate cortex, SSC: primary somatosensory cortex. Study assessment sessions were conducted at the Department of Surgical Sciences laboratory, Dunedin School of Medicine, Dunedin hospital, and the treatment sessions were conducted at the School of Physiotherapy laboratory, University of Otago, Dunedin, New Zealand. Feasibility measures were assessed throughout the study period. Treatment acceptability and satisfaction was assessed immediately post-intervention. Primary and secondary outcome measures and mechanistic outcome measure (EEG) were collected at baseline, immediately post-intervention, and at 1-week and 1-month post-intervention.