INTRODUCTION
epilepsy
FOCAL SEIZURES, EPILEPSY
Lacosamide is an antiseizure medication (ASM). It is a functionalised amino acid that selectively enhances slow inactivation of neuronal voltage‐gated sodium channels.Several trials have investigated the efficacy and safety of oral formulations of lacosamide in pediatric patients. The efficacy and tolerability of adjunctive lacosamide in patients aged 4 to 17 years with uncontrolled focal seizures was demonstrated in a Phase 3 double‐blind trial.The safety and tolerability of IV lacosamide has been established in adults with focal seizures.At the time that this trial (EP0060; NCT02710890) was conducted, the IV formulation of lacosamide was indicated in the United States for temporary use in patients aged 17 years and older only. The primary objective of this trial was to evaluate the safety and tolerability of IV lacosamide infusions in pediatric patients with epilepsy ≥1 month to <17 years of age.