Introduction
hyperglycaemia, diabetes
HYPERGLYCAEMIA, DIABETES
Postprandial glucose elevation and prolonged postprandial hyperglycaemia are risk factors for diabetes [Mulberry leaf extract (MLE), which contains 1-deoxynojirymycin (DNJ), has blood glucose-lowering and antidiabetic properties [A possible mechanism to explain the glucose-lowering effects of DNJ intake has been suggested; DNJ acts as an inhibitor of intestinal α-glucosidase by inhibiting the binding of substrates to the enzyme [In this study, we examined the timing effects of acute MLE intake on postprandial glucose levels in healthy adults. We hypothesised that the glucose-lowering effects of MLE may be greater in the evening because glucose tolerance is worse in the evening.