Conclusions
sepsis, critically ill
SEPSIS, CRITICALLY ILL, SEPTIC SHOCK
Among mechanically ventilated adult medical ICU patients without sepsis or septic shock, enteral citrulline administration did not result in a statistically significant reduction in SOFA score during the first 7 days after enrollment or a significant improvement in selected immunological parameters. Our data suggest no beneficial effect of L-citrulline on the outcome of critically ill patients treated with invasive mechanical ventilation.