Authors’ contributions
YZ, MC, HD and LQ designed the study. YZ, MC, YH, WZ, XH, GZ, XM, PQ, DS, YL, WH and PA did the trial and collected the data. PA, HL, SY and QM analyzed the data. YZ, YH, MC, PA, HL, QM, HD and LQ interpreted the data. QM wrote the manuscript. All authors had full access to all the data in the study and had critically reviewed the manuscript and approved the final manuscript. All authors vouch for data accuracy and fidelity to the protocol.