Cohort characteristics
For this nested mucosal sub-study of the ECHO trial, we included a total of 188 women with matched endocervical cytobrush samples obtained prior to, and one month after contraceptive initiation (DMPA-IM, Demographics and metadata of ECHO subjects recruited to substudy of mucosal transcriptomics.BMI; body mass index, KEMRI; Kenya Medical Research Institute (Kisumu; Kenya), sd, standard deviation, Wits RHI; (Johannesburg; South Africa). *Median and interquartile range. A retrospective power analysis of each study arm helped to demonstrate that for majority of transcripts detected at a reasonable level above background (>10 reads counts), at 