Statistical analysis
glucose disposalData
Reflecting the nature of this proof-of-concept, experimental medicine study, robust clinical date upon which to formulate accurate sample size estimates are lacking. Data from euglycaemic clamps suggest that prednisolone may cause a >20% decrease in glucose disposalData were analysed using SAS 9.4 for Windows (Copyright © 2013, SAS Institute Inc., Cary, NC, USA) and STATA for Windows, StataCorp. 2021 (Stata Statistical Software: Release 17. College Station, TX: StataCorp LLC) and the PROC GLM command in SAS 9.4 for Windows (Copyright© 2013, SAS Institute Inc., Cary, NC, USA). All recruited participants were included in the safety analysis and all participants who completed the study per protocol were included in the primary analysis. A data monitoring committee oversaw the study.