Ethics Statement
The Oxford University Clinical Trials Research Ethics Committee (Reference 52-19) and the Ghana Health Service Ethics Review Committee (Reference GHS-ERC 014/07/19) approved the study. For participants aged 6 months to 12 years, parents/guardians provided written consent, and for participants aged >12 years to <18 years, written assent was sought from them, and consent was given by their parents/guardians before engaging in the study. The study was conducted in accordance with Good Clinical Practice and the Helsinki Declaration for biomedical research on human subjects. All eligible patients gave informed consent or assent before enrollment.