5. Conclusions
OROPHARYNGEAL CANCER, ADVERSE EFFECTS, DISEASE
The findings of this study suggest that intake of Nutri-PEITC Jelly with 20 mg PEITC/day for 1–3 months is safe with minimal adverse effects. The supplementation may re-activate p53, stabilize the disease, improve the quality of life and progression-free survival in patients with advanced-stage oral and oropharyngeal cancer. Further studies in a larger population and various dosages are warranted to confirm that Nutri-PEITC Jelly could be functional food for tertiary chemoprevention in oral and oropharyngeal cancer.