Background
CKD, transfusion-related iron, anemia
HYPOXIC, ANEMIA
The prevalence of anemia increases with the progression of CKD [The clinical application of ESAs can increase hemoglobin concentration without the risk of transfusion-related iron overload, substantially improving patients' quality of life [By simulating hypoxic environment, roxadustat effectively inhibits HIF-PHD activity and increases the accumulation of HIF [