Limitations
The present results indicate that gentle mechanical skin stimulation with microcones is a self-care method, which is effective for improving subjective and objective measures and is safe to be used. In contrast, one of the limitations of the present study is a small, non-blinded study without controls. Psychological factors such as placebo effect, and also non-specific acupressure effect cannot be excluded from the effect of microcones in this study. The flat surface disc without microcones [