Results
dyspnea, fatigue
ADVERSE EVENTS, RECRUITMENT
Twenty-five consecutive eligible subjects were randomly assigned to either the intervention group (n = 13) or the control group (n = 12), without dropouts and relevant adverse events occurring during the study (Fig. Flow of recruitment of study subjects. A total of 25 subjects were eligible for inclusion and underwent randomization in the study, with 12 subjects in the control group (sham- PEP device) and 13 subjects in the intervention group (PEP device)Baseline characteristicsDefinition of abbreviations: FEVCompared with the control group, 6MWD (− 71.67 ± 8.70 m (95% CI [− 89.67, − 53.67]), Primary efficacy and safety outcomesDefinition of abbreviations: 6MWD = 6-min walking distance; Initial Borg-Dyspnea = Modified Borg scale for dyspnea at the beginning of the 6-min walk test; End Borg-Dyspnea = Modified Borg scale for dyspnea at the end of the 6-min walk test; Initial Borg-Fatigue = Modified Borg scale for fatigue at the beginning of the 6-min walk test; End Borg-Fatigue = Modified Borg scale for fatigue at the end of the 6-min walk test; PPrimary efficacy and safety outcomes. Compared with the control group, the initial SSecondary outcomesDefinition of abbreviations: Initial SSecondary outcomes. 