Participants
A total of 70 participants volunteered to participate in this clinical trial. Subjects were suitable for eligibility if they were: (i) apparently healthy; (ii) 18–60 years of age; (iii) non-smokers; (iv) without overt pathologies; (v) not taking drugs regularly; and (vi) committed to follow instructions of the research team at the testing time. The individuals were informed about the experimental protocol and all provided informed written consent before participating. The study protocol was approved by the Regional Ethical Committee (Center Italy Section) N12017052018.