Background
lung injury, acute lung injury, ARDS
ACUTE RESPIRATORY DISTRESS SYNDROME, ARDS, MULTIPLE ORGAN FAILURE
Acute respiratory distress syndrome (ARDS) is a life-threatening inflammatory lung injury that allows fluid to leak into the lungs and is often associated with multiple organ failure [Preclinical studies using animal models of ARDS have demonstrated that treatment with mesenchymal stem cells (MSCs) can reduce the severity of acute lung injury [The stem cell product invimestrocel (MultiStemClinical trials for treatments targeting biological pathways thought to be dysregulated in ARDS have been mostly inconclusive, and this may in part be due to the heterogeneity of ARDS [