Research population
carious lesions, allergy, gingivitis, plaque-induced gingivitis, diabetes
SYSTEMIC DISEASE, ALLERGY, GINGIVITIS, IMMUNE SYSTEM DISORDER, DIABETES
Forty-two patients were chosen based on eligibility criteria as follows:
Criteria for inclusion.The participants (patients), who meet the inclusion criteria for gingivitis, were over 18 years of age, having at least twenty functional teeth (five in each quadrant) and plaque-induced gingivitis GI ≥ 1 [
Criteria for exclusion.The persons with the following conditions: Probing depth > 3 mm, any systemic disease or condition capable of modifying the gingival tissues (pregnancy or breastfeeding, diabetes, immune system disorders), history of taking antibiotics in the past three months, taking medications that can affect gingival tissues (steroidal and non-steroidal anti-inflammatory drugs, calcium channel blockers, phenytoin, cyclosporine A), history of allergy, undergoing periodontal treatment during the last six months, active carious lesions, undergoing orthodontic treatment, having crowns or implants, and mouth breathing excluded from the study.