Author contributions
MST
VD, PB and AE designed research. AM, RG, PJB, MST, ES, BH, MS, MV, JMZ, UBK, SWK, JT, UD, JM, AV and AR collected data. MF, CK, GK, HE, MD and CB did the central PET review. HK and IB performed statistical analyses. MF, ASJ, HK, BvT, PB, AE and DAE analyzed and interpreted data. MF, ASJ and HK wrote the first draft of the manuscript. All authors contributed to data interpretation, reviewed the draft, and approved the final version of this report.