INTRODUCTION
OUD
DISORDER
Opioid use disorder (OUD) is a growing issue globally (Jayawardana et al., Pharmacologic treatment options for several SUD (e.g., opioids, stimulants, cannabis, alcohol, phencyclidine and other hallucinogens, inhalants, sedatives, anxiolytics, or hypnotics; tobacco and other or unknown substances) are limited. NAC is a sulfur‐containing agent that is widely studied for its anti‐inflammatory and anti‐oxidant impact (Ghaderi et al., NAC treatment appears tolerable, safe, and affordable (Deepmala et al., 