Imaging rationale
FOP, HO lesions
Imaging by In LUMINA-1, A previous retrospective study demonstrated the utility of PET in FOP patients to identify active HO lesions by demonstrating that, over a period of 5–20 months, only those lesions with high PET signal showed growth by CT, whereas lesions with low PET signal (equivalent to that of the normotopic skeleton) showed no growth by CT