Peanut sensitization
peanut allergy
PEANUT ALLERGY, PEANUT ALLERGY
In both individual and pooled study results, skin prick test sensitization to peanut was significantly reduced at 12 months among those introducing peanut early in comparison with those avoiding or introducing them after 6 months of age. IgE sensitization to peanut at 12 months of age remained similar between the randomized groups (Figure In the ITT population, children with specific IgE to peanut ≥0.1 kU/L at enrollment had a 75% reduction in peanut allergy prevalence at 3–5 years of age (Peanut allergy prevalence by specific IgE sensitization status at enrollment—(A) intention‐to‐treat and (B) per‐protocol population; in Caucasian and non‐Caucasian children—(C) intention‐to treat and (D) per‐protocol population. Prevalence of peanut allergy in each randomized treatment group is shown in baseline sensitized (peanut‐specific IgE >= 0.1 kU/L) and unsensitized (peanut‐specific IgE <0.1 kU/L) subgroups for individual and combined studies in (A) ITT analysis and (B) PP analysis; in Caucasian and non‐Caucasian subgroups within individual and combined studies in (C) ITT analysis and (D) PP analysis. Number of peanut allergy (PA) and total number of participants (