5. Conclusions
AD, dementia
OXIDATIVE STRESS
The findings of this clinical trial, even with a short period of intervention in a small target population sample size, provide evidence of the positive impacts of probiotics in AD patients. We conclude that, with sufficient doses and a proper formulation of probiotic supplementation, serum BDNF can be enhanced along with a reduction in oxidative stress and an increase in antioxidants among dementia patients who have already been clinically diagnosed with AD. Probiotics might have potential benefits to slow down the decline in cognitive function among symptomatic AD patients. Further studies with a larger sample size and longer intervention durations are needed to confirm the clinical benefit of probiotics.