Measures
hemorrhage, tachycardia, hypotension
HEMODYNAMIC INSTABILITY, BILE LEAK, HEMORRHAGE, CAVITY, PNEUMOPERITONEUM

Total procedure time: considered from the beginning of the pneumoperitoneum until the end of the cauterization of the biopsied liver parenchyma. ◦ Time measured with a stopwatch and counted in minutes.
Time of liver biopsy with placement of 0.5-mm trocars (laparoscopic technique) + laparoscopic scissors biopsy: considered from the placement of the 1◦Time measured with a stopwatch and counted in minutes.
Time of liver biopsy with device placement (mini-laparoscopy technique) + biopsy needle apposition: considered from device placement until biopsy sample removal.◦ Time measured with a stopwatch and counted in minutes.
Representativeness of the sample: ◦ Size of the biopsy sample measured in centimeters.
Time of hemostasis: considered from the removal of the biopsy sample to the complete cauterization of the liver parenchyma. ◦ Time measured with a stopwatch and contact in seconds.
Occurrence of hemorrhage: ◦Measured by the dichotomous criterion (YES/NO),
taking into account the patient’s hemodynamic instability (tachycardia or hypotension). ◦ If positive for hemorrhage, assess resolution by
the dichotomous criteria (YES/NO).
Occurrence of bile leak: ◦ Measured by the dichotomous criterion (YES/NO), taking into account the leak of bile from the biopsy area.◦ If positive for bile leak, assess the resolution using the dichotomous criterion (YES/NO).
Quality of the biopsy sample: ◦Assessed in the anatomopathological examination according to the number of individualized portal spaces (using the same laboratory).◦ ≥ 5 portal spaces: satisfactory sample.◦ < 5 portal spaces: unsatisfactory sample.
Handling of the developed device: the surgeon's degree of satisfaction with the device position and design. The data were classified according to the response using the Likert scale [Ergonomics of the developed device: the surgeon's degree of satisfaction with the device's degree of comfort and safety. The data were classified according to the response using the Likert scale.Accessibility provided by the developed device: the surgeon's degree of satisfaction regarding access to the abdominal cavity and the performance of the biopsy. The data were classified according to the response using the Likert scale.