Safety
bisphosphonate-related, fatigue, femur fracture
HYPOCALCEMIA, ADVERSE EFFECTS, SIDE EFFECTS, OSTEONECROSIS OF THE JAW
Side effects were rarely found. There was one patient who experienced grade 3 fatigue after administrating a single dose of alendronate, which led to drug discontinuation. No bisphosphonate-related adverse effects were found during the study period, including hypocalcemia, gastrointestinal side effects, osteonecrosis of the jaw, or atypical femur fracture.