Study cohort
Among the 205 participants enrolled in Protocol AB, 204 (>99%) completed the questionnaire at baseline and provided activity impairment data; 94 of 204 (46%) were employed at baseline, and 87 of 94 (93%) employed participants provided data on work productivity loss. Whether the participant was not working due to vision problems was not collected. Considering the cohort of participants who provided activity impairment data (N = 204), the mean age was 57 years, 89 were women (44%), mean study eye visual acuity was 34 letters (approximate Snellen equivalent 20/200), and mean activity impairment was 57%; most participants self-identified as White (83 [41%]), Hispanic or Latino (83 [41%]), or Black/African American (27 [13%]) (