Introduction
obesity, obesity pathologies, obese, chronic non-communicable diseases
OBESITY, OBESE, CHRONIC DISEASES, INSULIN RESISTANCE, DISEASES
The etiology of chronic non-communicable diseases such as obesity is multifactorial, including genetics and the environment (Considering this, the incessant search for nutritional intervention strategies is essential to pursue the mitigation of obesity and its comorbidities. In this sense, the use of natural products and derivatives as non-pharmacological strategies can be an alternative in the prevention and treatment of acute or chronic diseases. These tools could contribute to preventing or reducing obesity-related negative outcomes, promoting longer life spans and better-quality lives (Nevertheless, in this study, we also intend to contribute to the construction of knowledge for clinical practice using anthropometric assessment and serum tests reachable to practitioners’ daily routines. Previous studies have shown that increased neck circumference in obese adults is related to increased cardiovascular and inflammatory risk, acting as an anthropometric predictor of cardiovascular and inflammatory risk (Several cellular mechanisms are involved in obesity pathologies such as the metabolic pathways activated by directly influencing the insulin signaling in insulin-target tissues such as the liver, eventually leading to insulin resistance (The increased incidence and prevalence of obesity-related comorbidities is a concern still unsolved by worldwide public health regulators. Despite efforts to mitigate obesity, little effect has been noticed on the increase of all diseases associated with it (Therefore, in this study, we aim to apply our previously developed supplement composition containing yeast β-glucan, prebiotics, minerals, and 