Ethics approval and consent to participate
We confirmed that all experiments were performed in accordance with declaration of Helsinki. Before the experiment, approval of the study and informed consent of the participants were obtained. The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. This study was approved by the Scientific Research Ethics Committee of Qilu Hospital Shandong University(KYLL-202210-24, November 2022).