Adherence assessment
Adherence assessment will be performed. To determine the subject's adherence, which should generally be between 80 and 120% of medication adherence, subjects should return the experimental drug after the treatment period.Adherence = actual medication dose/theoretical medication dose × 100%.Actual dose = total amount of medication dispensed—(total amount of remaining return + total amount of lost).Theoretical dose = the dose of each time × the number of times of the test drug.Good adherence: 80% to 120%.