The effect of denosumab on DTCs
TNBC
We inquired, whether neoadjuvant add-on denosumab treatment, framed by the GeparX study [Effect of denosumab on DTC-eradication. Bar chart showing DTC-eradication rates in patients with NACT vs. patients with NACT + denosumab. Taken together, denosumab did not increase the overall DTC-eradication rate by NACT. However, subtype analysis shows a numerical trend towards a possible effect of denosumab on DTCs in TNBC.