Introduction
upper gastrointestinal (GI) bleeding, Stress Erosions
Approximately 2–4% of adults acutely admitted to an intensive care unit (ICU) develop upper gastrointestinal (GI) bleeding [REVISE (Re-Evaluating the Inhibition of Stress Erosions) is an ongoing international randomized trial, the objective of which is to determine the effect of pantoprazole versus placebo on the primary This document outlines the statistical analysis plan (SAP) for REVISE, reported using current guidelines [