Time to first composite cardiac event
cardiovascular death
CARDIAC EVENT, MYOCARDIAL INFARCTION, EVENT, EVENTS, HEART FAILURE
The overall median time to event or censoring was 12.1 months (interquartile range 1.8-13.9), with maximum follow-up at 44.5 months and similar duration of follow-up in both arms. The 12 month composite cardiac event rates were 34.0% (95% bootstrap confidence interval 29.9% to 37.8%) and 36.2% (30.2% to 42.1%) for the GRS arm and the standard care arm, respectively (hazard ratio 0.89, 95% confidence interval 0.68 to 1.16; Kaplan-Meier plot of time to first clinical outcome as composite of cardiovascular death, non-fatal myocardial infarction, new onset heart failure, and cardiovascular readmission. GRACE=Global Registry of Acute Coronary EventsThe proportion of participants dying from cardiovascular causes within the first 12 months was 3.3% (95% confidence interval 2.7% to 4.1%) and 3.5% (2.4% to 4.3%) for the GRS and standard care arms, respectively (hazard ratio 1.11, 95% confidence interval 0.77 to 1.59; Kaplan-Meier plot of time to first clinical outcome as component parts of cardiovascular death, non-fatal myocardial infarction, new onset heart failure, and cardiovascular readmission. GRACE=Global Registry of Acute Coronary Events