Systemic chemotherapy
All patients must have a pre-therapy CT scan no later than 4 weeks before starting systemic treatment. The chemotherapy used will be preferentially the XP scheme, which consists of oral capecitabine (2,000 mg/mOn D1 of each cycle, the infusion of IPC with PXT will be performed before the intravenous cisplatin infusion. On D8, when only PXT is infused, the patient must remain at rest/observation for 2 h after the end of the infusion.