Results
herpes lesions, astigmatism, chalazion, epiblepharon, herpes simplex
ADVERSE EVENTS, ASTIGMATISM, HERPES LESIONS, CHALAZION, SCARRING, HERPES SIMPLEX
This study included 89 eyes from 50 patients (22 males and 28 females) of the 132 patients who were evaluated for eligibility. The mean age of the patients was 7.5 years (range: 3–12 years). The incision method was assigned to 25 patients with 45 eyes at random, whereas the suture method was assigned to 25 patients with 44 eyes. The incision method was assigned to 8 (32%) males and 17 (68%) females, while the suture method was assigned to 14 (56%) males and 11 (44%) females.No statistically significant difference was observed in terms of age, sex, and preoperative astigmatism between the two groups (Table Characteristics of patients enrolled in this study.n.s., not significant.At 1 month after surgery, the incisional surgery group revealed well-corrected, under-corrected, and over-corrected treatment results in 43 (95.6%), 2 (4.4%), and 0 (0%) eyes, respectively (Table Surgical outcome at 1-month and 6-month follow-up after epiblepharon surgery.At 6 months after surgery (primary endpoint), the incisional surgery group revealed well-corrected, under-corrected, and over-corrected treatment results in 35 (77.8%), 10 (22.2%), and 0 (0%) eyes, respectively (Table In the incisional group, the mean preoperative astigmatism was 1.21 ± 1.06 D, and the mean postoperative astigmatism was 0.97 ± 1.04 D (Table Changes in astigmatism at 6-month follow-up after epiblepharon surgery.A statistically significant decrease was observed in astigmatism after surgery (The following two adverse events were recorded as part of a safety assessment. A 6-year-old boy who had incisional surgery in both eyes developed a chalazion in the right eye 11 weeks later, which coincided with the incision site at the lower eyelid. Conservation treatment with antibiotic drops and ointment resulted in the resolution of chalazion within 2 weeks without scarring. Additionally, 12 weeks after the bilateral lower eyelid suture surgery, a 4-year-old boy was found to have herpes simplex in the upper and lower eyelids of both eyes. Conservative dermatological treatment with antiviral ointment resulted in the resolution of herpes lesions within 2 weeks without scarring. In both cases, the relationship between the surgery and symptoms is unclear. No other adverse events were reported. Supplementary Fig. 