Effect of hemodialysis and bradykinin receptor blockade on blood pressure
reduction of blood pressure, decrease in systolic blood pressure, IDH, intradialytic hypotension
INTRADIALYTIC HYPOTENSION, HEART
Icatibant treatment did not affect blood pressure during hemodialysis compared to placebo treatment in the overall group (Figure We next analyzed the effect of icatibant on blood pressure in patients with and without intradialytic hypotension.The hemodialysis variables in patients with and without intradialytic hypotension are shown in Table 
Hemodialysis variables in patients with and without intradialytic hypotensionVariables are expressed as mean ± SD, median (range), unless otherwise specified. IDH, intradialytic hypotension (decrease in systolic blood pressure equal to or greater than 20 mmHg). spKt/V, single pool Kt/V. ACEi, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blockers; CCB, calcium channel blockers
Effect of icatibant on systolic blood pressure (SBP) during hemodialysis in patients with a reduction of blood pressure ≥ 20 mmHg (n = 7). 
Effect of icatibant on heart rate during hemodialysis in patients without (n = 4, A) and with (n = 7, B) intradialytic hypotension (IDH, a reduction of blood pressure ≥ 20 mmHg). Heart rate was measured every 15 min before and during hemodialysis
Episodes of intradialytic hypotension during icatibant and placebo treatmentsIDH, intradialytic hypotension (decrease in systolic blood pressure equal to or greater than 20 mmHg).Icatibant did not affect heart rate during hemodialysis in patients with intradialytic hypotension (Fig. 