1. Introduction
PsA, PsA., fatigue, Psoriasis, muscle damage, arthritis, psoriasis, musculoskeletal pain, pain, PsO, Fatigue
PSORIASIS, ARTHRITIS, PSORIASIS, SECONDARY, INFLAMMATORY SKIN DISEASE
Fatigue and musculoskeletal pain are also frequent in patients with psoriasis (PsO) without arthritis (PsA). The current study aimed to assess the impact of an intervention program based on aerobic training to reduce fatigue and musculoskeletal pain in patients with PsO without PsA. A total of 118 male patients with PsO volunteered in the current interventional study and were randomly allocated to the experimental (Psoriasis (PsO) is a chronic, immune-mediated inflammatory skin disease with a high prevalence in Western societies [However, musculoskeletal symptoms, including pain and fatigue, are highly prevalent in patients with PsO, having a negative impact on their physical function and quality of life [For the reasons already mentioned, PsO may cause great physical, emotional, and social burdens that inevitably lead to considerable use of medical care and economic resources in both private and public health services [In a more detailed way, increasing physical activity has been inversely associated with the risk of psoriasis, as the most physically active quintile of participants during a 1,195,703 person-years of follow-up (14 years, 1991–2005) had a lower multivariate relative risk (RR) of PsO (0.72 (95% CI, 0.59–0.89; Additionally, high levels of physical activity have been shown to reduce the risk of PsA in patients with PsO in a recent population-based study in Norway [In spite of the above-mentioned pieces of evidence, several studies have demonstrated that patients with PsO generally exhibited more sedentary behavior and were less physically active than matched healthy controls [Finally, this study aimed to assess the influence of an intervention program based on aerobic training on reducing fatigue and musculoskeletal pain in adult patients with psoriasis without PsA. The secondary objective was to determine the effects of the intervention on body composition, maximal aerobic power, and serum muscle damage markers.