PCOS and microbiome interactions
PCOS
Our group was among the first to discover lower bacterial abundances and significant differences in stool microbiome composition between women with PCOS and healthy controls in 2017 [Gut microbiota also play a critical role in phytoestrogen metabolism in our body. For women with PCOS, the isoflavone metabolite equol may be of particular interest. Daidzein, one of the most abundant isoflavones found in plant products, can only be metabolized to equol via certain bacterial species in the human gut [Several studies have already tested probiotic products for therapeutic use for women with PCOS [