Background and rationale {6a}
pain
ADVERSE EFFECTS, FIBROMYALGIA
Opioids, primarily oxycodone, continue to be widely prescribed for chronic noncancer pain (including fibromyalgia), despite the awareness that such medication provides only short-time pain relief, leads to dose accumulation due to tolerance development, has numerous adverse effects, and is difficult to wean due to development of dependence and withdrawal symptoms [We previously showed that inhaled pharmaceutical-grade cannabis, containing both Δ