Low-grade inflammation
Serum hsCRP was analysed using an automated colorimetric immunoassay on a Dade Behring Dimension RXL autoanalyzer (Siemens Healthcare) in a certified laboratory (TYKSLAB, the Hospital District of Southwest Finland). The lower limit of detection was 0·1 mg/l. The data are expressed as mg/l. A high-throughput proton NMR spectroscopy metabolomics platform (Nightingale) was used to quantify GlycA