Randomization
The 44 study clusters will be grouped into 10 categories, by island (Anjouan and Mohéli) and in relation to the PEOPLE trial (former arm 1,2,3, or 4, or new). Within each group, they will be ordered by decreasing baseline prevalence and pairs will be constituted of successive clusters. Within each pair, one will be randomized to arm 1, and the other to arm 2. An independent sponsor biostatistician will prepare the randomization schedule using SAS 9.4 (SAS Institute, Cary NC).