Appendix A
satiety, wheat biscuit
SEPARATION, BLOOD
CONSORT diagram for the study of effects of order and temporal separation of fruit and cereal in a meal on glycaemic response and appetite.Changes in the four dimensions of appetite (all in grey) and their mean (bold black) plotted against time. The treatments are described in Correspondence between increments in blood glucose concentration (dotted line, mmol/L) and satiety (solid line, cm). Means ± sem.Glycaemic response to kiwifruit (KF) and wheat biscuit (WB), with KF ingested 30 min before wheat biscuit (WB) (treatment KF-30/WB; bold, black markers), at the same time as (KF/WB), or 30 min after WB (WB/KF+30), compared with wheat biscuit alone (WB74). All meals delivered 51.7 g of available carbohydrate. Order and timing have substantially reduced response amplitude in the KF-30/WB treatment. Treatments are summarized in Blood glucose response to WB alone at an intake of 51.7 g of carbohydrate (WB74), to 37 g of wheaten biscuit (WB), to 200 g of kiwifruit (KF200), each delivering 25.85 g available carbohydrate, to the sum of the two (KF200+WB; theoretical), and to 200 g KF ingested 30 min before 37 g WB (KF-30/WB). WB starts at 30 min to coincide with its ingestion in the KF-30/WB treatment. KF has suppressed the response to WB in the KF-30/WB treatment compared with the response to WB alone. Treatments are summarized in Values for incremental areas under the curve (IAUC) of blood glucose responses (BGR IAUC, presented visually in Differences between maxima of the blood glucose response curves shown in 