Neuropsychology outcomes
n=2/8, neurodevelopmental impairment
Thirteen participants (72%; IVIG n=8/10 (80%); placebo n=5/8 (63%)) had a neuropsychology assessment at 12 months after randomisation by a blided assessor. Four of these participants (30%; IVIG n=2/8 (25%), placebo n=2/5 (40%)) were unable to complete the full battery of assessments due to attentional or behavioural needs.Five participants (28%; IVIG n=4/10 (40%), placebo n=1/8 (13%)) had a score of≥ 85 (indicating normal development) for full-scale IQ (FSIQ), six (33%; IVIG n=4/10 (40%); placebo n=2/8 (25%)) for verbal comprehension, five (28%; IVIG n=4/10 (40%), placebo n=1/8 (13%)) for visual spatial; four (22%; IVIG n=4/10 (40%)) for working memory; and four (22%; IVIG n=3/10 (30%); placebo n=1/8 (13%)) for perceptual reasoning (PRI). Two participants (IVIG n=1, placebo n=1) were assessed using the Bayley scale of infant development, one participant (IVIG n=1) had severe neurodevelopmental impairment while the other (placebo n=1) had a normal neurodevelopmental outcome. These results are displayed in Neuropsychology outcomes at 12 months after randomisationKey: green = normal neurodevelopmental score, yellow = mild impairment, red = severe impairment.*Young person unable to complete full battery due to attention or behavioural needsFSIQ, full-scale IQ; PRI, perceptual reasoning index; VCI, verbal comprehension index; VSI, visual spatial index; WMI, working memory index.