Conclusions
In this primary care based trial, 58.5% of patients had at least one prescribing recommendation implemented. Despite this, the results as to whether the medication review intervention centred around the use of an eCDSS led to an improvement in appropriateness of medication or a reduction in prescribing omissions at 12 months compared with a discussion about medication in line with usual care were inconclusive. Nevertheless, the intervention could be safely delivered without causing any harm to patients.