Discussion
DISEASES
We found substantial differences between transcutaneous and arterial COSo far, the dynamics of the COAlthough the bias shown in the Bland-Altman plots in Researchers tested the accuracy of pReliability can be limited by some technical pitfalls that can lead to inaccurate measurements: trapped air bubbles between the skin and the sensor, incorrect sensor placement, and incorrect sensor maintenance [It is not completely clear why the COIn clinical practice, it might be useful to compare transcutaneous COIn healthy patients without pre-existing diseases, transcutaneous COPotential limitations of our study are the single-centre study design and the fact that all measurements were made in apneic patients of our specific patient population (compare inclusion/exclusion criteria). Further studies of other users in different settings and including different patient populations are needed to confirm and generalize our observations and their clinical implications. As our observation period was only 15 minutes, we cannot make conclusive statements for longer periods of time and if these devices might be used as trend monitors. Approximately 7.3% of data measured after the first minutes had to be excluded from the analysis (based on previously published data) to verify correct measurements, e.g., a rise of CO