Competing interests
FOUNDER, APC, BLOOM
B.T.T. and G.S. led data analysis and were not involved in study design or trial execution. R.D. is a co-founder and CEO of Seed Health (SH) and Luca Biologics. J.V., A.F., E.A.M., C.E.M., and J.F.P. are members of the SH  Scientific board. SH Scientific board members and employees hold equity positions in SH unless otherwise stated. B.T.T., G.S., N.V., P.A.B., G.R., and E.K. are consultants for SH and were not involved in the microbial synbiotic or clinical trial design. B.T.T. additionally consults for Enzymetrics Bioscience and holds an equity position in SH. S.G.P. and G.A.G. are employed by SH and were not involved in microbial synbiotic or clinical trial design. B.P.C. receives potential royalties from the Rome Foundation for the usage of the modified Bristol Stool Form Scale for Children, which is not used in this study. A.F. is additionally a cofounder and stockholder of Alba Therapeutics, a company developing treatments complementary to the gluten-free diet by exploiting gut permeability. E.A.M. is additionally on the Scientific Advisory Board of Axial Biotherapeutics, Pendulum Therapeutics, Bloom Science, Mahana Therapeutics, APC Ireland, Danone, and Amare. J.F.P. is the Founder and Chief Scientific Officer of Diversigen, Inc. and is on the Scientific Advisory Board for 4D Pharma, PLC. C.E.M. is cofounder of Biotia and Onegevity Health. J.V. is on the scientific advisory boards for Biomica and Plexus Worldwide.