Neuromonitoring
cranial bone deformations
BEST, EDWARDS
ICP was measured using the Neurovent monitoring system via optic-fiber transducer (Raumedic, Munchberg, Germany); mean ICP value (mICP) over the 10-min recording was therefore calculated. NICPW were assessed using the B4C (B4C; Brain4care Corp., São Carlos, Brazil) sensor, which consisted into a monitor that quantifies local cranial bone deformations using specific sensors [NICPW calculations were performed from the average of the pulses within each minute of monitoring, likewise, mICP were calculated as the average of each minute of the session. The parameter of interest obtained from the analysis of NICPW was the P2/P1 ratio, that is, the ratio form dividing the amplitudes of these two peaks. As demonstrated previously, the amplitude of P2 increases with IHT [Arterial blood pressure (BP) was recorded invasively using a radial artery catheter (Leadercath Arterial polyethylene catheter 18-gauge, 10 cm length, 0.8 mm internal diameter, 1.2 mm external diameter, Vygon, Ecouen, France), connected to a disposable pressure transducer (VAMP Plus system; Edwards Lifesciences, Irvine, CA, USA) and to a Philips MX800 IntelliVue monitor (Philips Medical System; Best, The Netherlands).