Author contributions
P.
RECRUITMENT
C.M.D., M.J., U.S., J.G., A.L., M.S., P.D., R.F.S. and C.M.-T. designed the study. C.M.D., U.S., J.G., R.F.S. and C.M.-T. wrote the general protocol. A.L., A.S. and M.S. wrote the protocol on blood donation procedures. M.J., P. Stelmach, U.M., M.A.W., C.N., L. Bullinger, J.F-.S., M.B., N.A., O.W., T.W., M.J.G.T.V., S.S., M.M.A., F.H., M. Kreuter, P.-R.T., B.H., M.H., A.M., M. Kiehl, O.H., M.-A.W., C.C.S., C.C., T.P., M.R., W.V.K. and H.-M.L. participated in patient recruitment. M. Gronkowski and J. Klemmer organized plasma donor recruitment. A.L. and S.M. supervised blood donations and procedures. M.S.-C., M. Gaeddert, N.H., H.-G.K., B.M., P. Schnitzler, S.P., R.B. and K.K. supervised the laboratory procedures. C.M.D., R.F.S. and C.M.-T. supervised the project. C.M.D., M.J., U.S., J.G., R.F.S. and C.M.-T. performed the general analysis; J. Krisam and L. Baumann, the statistical analysis; and J.S., the data management. C.M.D., M.J., U.S., J.G., S.F.W., R.F.S. and C.M.-T. wrote the manuscript. All authors edited and approved the manuscript.