Infusion duration
In Part A, median duration for the first infusion was 3 h 44 min for patients receiving the weight-based infusion and 3 h 25 min for patients who switched to the fixed-volume infusion method. The median duration decreased to 2 h 49 min and 1 h 48 min for the second infusion, 2 h 45 min and 1 h 18 min for the third infusion, and 2 h 35 min and 1 h 18 min for subsequent infusions.In Part B, with the fixed-volume infusion method, the median duration of infusion decreased from 3 h 41 min for the first infusion to 1 h 55 min for the second infusion, 1 h 17 min for the third infusion, and 1 h 20 min for subsequent infusions.