Statistical analysis
gastric cancer
GASTRIC CANCER
Our trial was designed as a therapeutic exploratory study to compare our CapeOX therapy with historical reference data in the first-line treatment of older patients with AGC. However, at the time of the trial’s planning, historical reference data for older gastric cancer were scarce. Koizumi and Imamura reported the results of S-1 monotherapy in older patients with AGC, with a median OS of 10.4 months and 9.2 months, respectively [The primary analysis was based on the full analysis set (FAS), comprising all enrolled patients excluding those deemed ineligible after enrollment. We used the Kaplan–Meier method to estimate survival curves and Greenwood’s formula to calculate 95% confidence intervals (CIs) for survival rates. Log-rank test was applied to compare survival curves. Statistical analyses were conducted using SAS version 9.4 (SAS Institute, Cary, NC).