Treatment methods
DVT, dehydration, infection, pain, lower extremity pain
DEHYDRATION, INFECTION, DVT
88 patients were all under general anesthesia, prone position. The observation group received a unit-dose of TXA (Containing 100 mL normal saline and 1 g TXA, Drug batch No. H20031101; Chongqing Lummy Pharmaceutical Co., Ltd) intravenously 15 min before skin incision after general anesthesia. The control group was given 100 mL of 0.9% normal saline in the same way. The two groups had the same operation, that was, the standard PLIF, including bilateral fenestration and subtraction. A longitudinal incision was made centered on the diseased vertebral segment. The skin was separated layer by layer, subcutaneously to the spinous process, the bilateral paraspinal muscles were stripped, the spinous process, lamina, and articular process were exposed, and then the pedicle screw was placed, fenestration decompression, intervertebral discectomy, and bone graft fusion were performed. The incision was sutured layer by layer, and two negative pressure drainage tubes were placed. When the patients returned to the ward, they were given bed rest, routine use of antibiotics to prevent infection, and application of hormones, dehydration, anticoagulation and pain relief. Perioperative blood transfusion was red blood cell, and the standard of blood transfusion was that the hemoglobin level was lower than 70 g/L. The vital signs, surgical incision, sensation and movement of both lower extremities were observed. The condition for removing the drainage tube was when the drainage volume was less than 50 mL/24 h. When a patient suddenly presented with lower extremity pain, bilateral skin temperature, or unequal circumference, urgent ultrasonography was performed to determine whether there was DVT of the lower extremity.