Conclusions
VTE
Developing and testing system-wide implementation strategies to improve evidence-based prescribing remains an area ripe for further development in implementation science. DOACs, which have seen rapid recent growth as first-line treatment for AF and VTE, are commonly prescribed inappropriately and present an opportunity for exploring the potential of EHR-based communications to improve evidence-based prescribing, including through the use of DOAC pharmacist collaboration. Findings from this study can inform EHR alert and notification design for other health care systems, improve our understanding of whether and when to engage specialty pharmacists in care, especially for high-risk medications, and improve the long-term health of the patients that are prescribed DOACs.