Study procedure
Within two weeks of screening, participants attended a baseline fasting visit. Subsequent research visits were scheduled to take place after 16-18 weeks of study treatment, but participants were offered the opportunity to stop a treatment early and move on to the next treatment period if they were unable to tolerate the therapy. At the baseline and end of therapy visits, blood samples were collected for measurement of HbA1c, weight and blood pressure, and the participant’s experiences of the therapy and potential side effects were recorded (once-daily). Participants were compensated for travel expenses only.