Statistical analysis
DELETION
All data were analyzed by using the SPSS software (IBM SPSS Statistics for Windows, version 26.0; IBM Corp, Armonk, NY, USA) and GraphPad Software (GraphPad Prism for Windows, version 9.0.0; San Diego, California USA). Kolmogorov-Smirnov test was used to assess the normality of continuous variables. The normative continuous variables were presented as mean ± standard deviation (SD). Median and interquartile range (IQR) were used to describe continuous variables if non-normal distributed. Differences in baseline data were compared using Student’s t-test or Mann-Whitney U test for continuous variables and Fisher exact test for categorical variables. For those indicators of pre- and post-administration testing, such as BDNF, NEP, BNP, and Corin, Wilcoxon sign-rank tests were performed to assess differences. Two-way repeated measures ANOVA were used to analyze patients’ blood pressure monitoring status. Missing values were handled using a pairwise deletion method. A 2-tailed 