Primary outcome parameter – time to first alcohol use
DBS-EARLY
Overall, 11 out of 12 patients used alcohol during the first 6 months after randomization. In the DBS-EARLY ON group, one patient remained abstinent throughout the study and one patient remained abstinent for 5 months, while all patients in the DBS-LATE ON group had used alcohol by the end of month 6. The mean time to first alcohol use was 70.5 days (DBS-EARLY ON) and 29.7 days (DBS-LATE ON). There was no significant difference in terms of time to first alcohol use between the DBS-LATE ON and DBS-EARLY ON groups after the first 6 months of treatment (two-sided Log-Rank-Test, 