Fidelity, dose and reach of the SANDWICH intervention
Across the paediatric ICUs, the intervention reached a high proportion of patients (median 82%, IQR 77%, 89%). The median (IQR) of percentage adherence to the intervention components across the paediatric ICUs was highest for setting targets on the ward round (ventilation, 90% [QR 81, 96]; sedation, 85% [IQR 63, 89]) and COMFORT assessment (83% [IQR 82, 91]); moderate for daily screening (74% [IQR 66, 83]) and lowest for undertaking a SBT when criteria were met (40% [IQR 31, 51]). The mean of all components was 75% (range 59–85%). The proportion of intervention adherence within each ICU is presented in 