Sample Size
The required sample size in each group was calculated using G*Power (University Kiel, Germany) software. There have been no exact incidences of RSS after RY or URY evaluated based on a large cohort. A minimum sample size of 44 patients per randomization arm was estimated to yield a statistical power of at least 0.8 with an alpha of 0.05 and a medium effect size (d = 0.3). Considering a loss to follow-up of up to 10%, at least 50 patients should be included in each group.