Serum samples
BLOOD
Blood draws were done at the trial’s site (Weizmann Institute of Science) or at the central medical laboratory of the trial (AMC Medical Center Laboratory, Ltd.).Metabolite concentrations were measured in serum samples by Metabolon using an untargeted liquid chromatography coupled with mass spectrometry (LC–MS) on 20/03/2020Cytokine levels were produced by Olink using qPCR proximity extension assay (PEA) on 26/06/2020. Levels were presented as normalized protein expression (NPX) values in Olink Proteomics’ arbitrary unit before the data processing steps described above, 2 PCs were reduced and we ended up with 306 samples and 76 features.