2.8. Statistical Analysis
INFLAMMATION
We aimed to randomize 120 participants into the trial. This sample size was calculated based on the primary aim of the trial, change in liver fat [Statistical analyses were performed using the R statistical package version 4.0.3 [In exploratory analyses of the pooled data, we assessed the impact of reducing sugar intake, irrespective of randomization, on glucose tolerance and its determinants, the fasting serum lipid profile, blood pressure, and markers of inflammation. To assess the effect of reducing total sugar intake on our outcomes of interest, we split our data set into those with a reduction in total sugar over the intervention period (TS; TS