Background
cancer, AML
CANCER, DISEASE, AML
AML is primarily a disease of adults (median age at diagnosis 68 years) with a high unmet medical need [The introduction of monoclonal antibodies (mAbs) has largely improved treatment options and outcome of cancer patients [FMS-like tyrosine kinase 3 (FLT3, CD135) is a surface expressed member of the class III receptor tyrosine kinase family. In healthy cells, low levels of FLT3 are expressed on immature hematopoietic progenitors, dendritic cells and monocytes [