Methods
EMERGENCY
CEREHETIS was a prospective, randomized, open-label, active control, multicenter, parallel-group phase IIIb pilot study. The patients were enrolled across 8 centers in Russia – the Interregional Clinical Diagnostic Center (Kazan), Municipal Clinical Hospital #7 (Kazan), Kazan Federal University Hospital (Kazan), Perm Territorial Clinical Hospital (Perm), Emergency Medical Center (Naberezhnye Chelny), Leninogorsk District Hospital (Leninogorsk), Nizhnekamsk District Hospital (Nizhnekamsk), and Arsk District Hospital (Arsk) – from April 2018 to August 2020.