Ethics approval and consent to participate
The study protocol was approved by the Ethical Committee of Shanghai First Maternity and Infant Hospital (Ethical Committee No. KS21294, approval date: September 28, 2021). All methods were performed in accordance with the relevant guidelines and regulations. The trial was registered with the Chinese Clinical Trial Registry at chictr.org.cn (registration number, ChiCTR2100055050) on December 31, 2021. All participants provided their written informed consent before the trial.