Study population
diabetic, type 2 diabetes mellitus, Diabetes
TYPE 2 DIABETES MELLITUS, DIABETES
Japanese subjects with type 2 diabetes mellitus who had participated in the main UTOPIA study were asked to participate in this extension study. The sample size of the main UTOPIA study was calculated as follows: the increase in carotid IMT in diabetic patients is estimated to be 0.034 ± 0.054 mm/year (mean ± standard deviation [SD]), and a 1% improvement in hemoglobin A1c (HbA1c) levels improves IMT by 0.02 mm/year [The inclusion criterion for this extension study was as follows: subjects who had participated in the main UTOPIA study and provided written informed consent to participate in this extension study after a full explanation of the extension study. The exclusion criterion for this extension study was as follows: subjects deemed unsuitable for participation in this extension study by the investigators. The inclusion criteria for the main study were as follows: (1) Japanese patients with type 2 diabetes mellitus who are not achieving the glycemic control goals described in the “Treatment Guide for Diabetes 2014–2015” edited by the Japan Diabetes Society [