Summary of Primary and Secondary End Points at Week 12 in the Full Analysis Population
anemia, amenorrhea
HEAVY MENSTRUAL BLEEDING, ANEMIA, DYSMENORRHEA, REMISSION, BLOOD
Abbreviations: Hb, hemoglobin; VAS, visual analogue scale.SI conversion factors: To convert Hb to grams per liter, multiply by 10; platelet count to ×10Differences for continuous end points are shown as means, and differences for categorical end points are shown in percentage points.VAS scores range from 0 to 10, with higher scores indicating more severe dysmenorrhea.Definition of heavy menstrual bleeding is more than 100 of the Pictorial Blood Loss Assessment Chart score.Definition of the complete remission rate for heavy menstrual bleeding is the percentage of patients achieving amenorrhea after 12 weeks treatment.Definition of total effective rate for heavy menstrual bleeding is the percentage of patients with reduction in Pictorial Blood Loss Assessment Chart score of at least 30% from baseline.Definition of anemia patients at baseline is the condition of having hemoglobin levels less than 12.0 g/dL quantity.Uterine volume was determined based on the diameters of 3 angles by transvaginal ultrasonography. The uterine volume was calculated as 0.52 × In fact, the VAS score significantly began to decrease at week 4 after mifepristone treatment (