Author contributions
YN, FK, TH, and HI designed the study. HH, SY, KY, KH, and YK performed sample collection and input data. FK advised on statistical findings. YN generated the random allocation sequence; YN, KH, and YK enrolled participants; and HH, SY, and KY assigned participants to interventions. YN, HH, and SY contributed to the statistical analysis. YN, HH, and SY wrote the first draft. All authors critically revised the report, commented on the drafts of the manuscript, and approved the final report.