Surgical therapy and perioperative outcomes
Nivo+CT, TRAEs, pulmonary embolism
PULMONARY EMBOLISM
In the Nivo+CT arm, all 22 (100%) patients underwent planned surgical resection, and the R0 resection rate was 90% (20/22). Median time from the last dose of neoadjuvant therapy to operation was 33 days (range 23–138), with four (18%) operations being delayed due to TRAEs in three patients and pulmonary embolism in one patient. Lobectomy was performed in 17 (77.3%) patients, wedge in one (4.5%) patient, segmentectomy in two (9.1%) patients and pneumonectomy in two (9.1%) patients (Supplementary Fig. In the Ipi+Nivo+CT arm, 20/22 (91%) patients underwent planned operation with 18 (90%) lobectomies, of which one was sleeve and one bilobectomy. One (5%) patient underwent segmentectomy, and one (5%) patient underwent left pneumonectomy (Supplementary Fig. 