The Mediating Analysis of Maternal Psychological Distress Between Treatment Allocation and Infant Neuropsychological Development
distractibility, depression, anxiety
The scores for the 3 types of temperament at 6 weeks (quality of mood, distractibility, and adaptability) in the digital GSH-MBI group were significantly lower than those in the control group. Thus, we used partial correlation analysis to explore the relationship between quality of mood, distractibility, and adaptability and maternal psychological distress at T2 or T3, adjusting for maternal psychological distress at T1. As shown in On the basis of the partial correlation analysis, we tested a total of 9 mediation models, including: the indirect effect of treatment allocation, through maternal depression symptoms at T2 or T3, to infant quality of mood; the indirect effect of treatment allocation, through maternal anxiety symptoms at T2 or T3, to infant quality of mood; the indirect effect of treatment allocation, through maternal pregnancy-related anxiety symptoms at T2 or T3, to infant quality of mood; the indirect effect of treatment allocation, through maternal depression or anxiety symptoms at T3, to infant distractibility; and the indirect effect of treatment allocation, through maternal anxiety symptoms at T3, to infant adaptability. The results showed that only one indirect effect (treatment allocation, through maternal pregnancy-related anxiety symptoms at T2, on infant quality of mood) was statistically significant. The standardized indirect effect of maternal pregnancy-related anxiety symptoms at T2 was 0.071 (95% CI 0.001-0.167; Mediation model of maternal pregnancy-related anxiety symptoms at T2 between treatment allocation and infant quality of mood. Standardized estimates are shown for relationships among treatment allocation, maternal pregnancy-related anxiety symptoms at T2, and infant quality of mood. T2: immediately after the intervention; 