Relative perfusion in the dorsolateral prefrontal cortex.
Perfusion shown for the acute time point (left) and the delayed time point (right). * = significant at At the acute time point, a significant effect of group was observed for the right IFG (Exploratory comparison of the two time points within groups showed that rCBF in the IFG decreased from the acute to the delayed time point in the PK (Exploratory correlation analyses conducted in the PK group between rCBF and subjective measures as well as plasma concentration showed the following results: At both time points significant correlations were only found between rCBF and subjective mood ratings. At the acute time point, a positive correlation was found between rCBF in the left DLPFC and positive affect after the ketamine infusion (