The effect of vitamin D supplementation on pain
bodily pain, Pain, pain
REGRESSION, CHRONIC PAIN
The mean PIQ-6 score was similar across the three surveys (∼50). There was no effect of vitamin D supplementation on the PIQ-6 score at any survey point or overall (
Effect of being randomised to vitamin D supplementation on PIQ-6 score, presence of some or more pain impact and presence of some bodily painPIQ, Pain Impact Questionnaire.Some or more pain impact: PIQ-6 score >50.Effect estimates comparing vitamin D with placebo (reference).Effect estimates adjusted for age, sex and state.Effect estimate calculated using all available records; generalised estimating equations with exchangeable correlation matrix used to account for intra-person correlation.Adjusted mean difference (95 % CI) estimated using linear regression.Adjusted prevalence ratio (95 % CI) calculated using log-linked binomial regression.Similarly, there were no significant differences between the vitamin D and placebo groups in the overall prevalence of some or more pain impact (PR 1·01; 95 % CI (0·99, 1·03)) or some bodily pain (PR 1·01; 95 % CI (0·99, 1·03)) (In the analysis of PIQ-6 score, there was a significant interaction between randomisation group and history of chronic pain at baseline (
Effect of being randomised to vitamin D supplementation on mean pain score within subgroups. Here effect estimate (mean difference) is comparing vitamin D with placebo and it is adjusted for age, sex and state. Mean difference is calculated using all available records; generalised estimating equations with exchangeable correlation matrix are used to account for intra-person correlation. 