The effect of A8G6 on the time to the COVID-19 recovery
When participants became infected with SARS-CoV-2 in both groups, RT-PCR tests or rapid antigen tests of their oropharyngeal swabs for COVID-19 and the COVID-19 related symptoms were continuously monitored and recorded. When SARS-CoV-2 RNA or SARS-CoV-2 related antigens could not be detected, it was defined as COVID-19 negative conversion. All subjects in both groups who became infected with SARS-CoV-2 during the trial period were observed the conversion to COVID-19 negative by the end of the trial. The time of SARS-CoV-2 negativity between groups showed no statistical differences (Time-to-event curve for time to viral clearance of SARS-CoV-2 in the full analysis population. Shown are cumulative incidence of COVID-19 negative conversion. Viral clearance was defined as conversion of SARS-CoV-2 RNA from positive to negative. There were 6 individuals in the control group with uncertain time of conversion of SARS-CoV-2 RNA from positive to negative. Negative conversion of SARS-CoV-2 was conducted by using Kaplan–Meier method and log-rank-test