Screening and enrollment
depressive disorder, Depression, AD
After informed consent is obtained for the P3 cohort, including consent to be contacted for nested trials, participants meeting the study definition of AD will be identified by research assistants using weekly data queries. For the purposes of this study, AD is defined as a score of 10 or greater on the Edinburgh Postnatal Depression Scale (EPDS), which has been validated to measure major depressive disorder against diagnostic interviews (sensitivity 87.7%; specificity 90.9%) in pregnant individuals [Written informed consent will be obtained in addition to the P3 cohort consent. Research assistants will screen participants further for eligibility and included participants will be randomized to receive the intervention or standard of care (control). Randomization will be conducted using computer-generated, block-randomization into an intervention group and a control group (receiving standard of care).