Treatment exposure
Neutropenia
NEUTROPENIA
The median number of treatment cycles was 11 (range, 1–63). The median relative dose intensities of oxaliplatin, irinotecan, bolus fluorouracil, infusional fluorouracil, and leucovorin were 62.8%, 60.2%, 13.1%, 76.5%, and 80.0%, respectively. Dose reduction and treatment delay occurred in 30 patients (85.7%). Neutropenia was the most frequent cause for both dose reduction and treatment delay (74.3% and 77.1%, respectively).