Maintenance therapy
DISEASE PROGRESSION, DISEASE
Maintenance therapy will be abemaciclib 150mg po BID together with temozolomide 200mg/mThe study team will maintain active contact via phone (every six months) with patients who do not go onto maintenance therapy, or with their home clinical team as part of long-term follow-up to collect information on his/her management of disease and survival post-trial. Once patients on maintenance therapy exhibit disease progression, they will continue long-term follow-up via phone (every six months) as part of long-term follow-up for survival.