Conclusions
CI-AKI, CIN, diabetic
DIABETES TYPE 2, CIN
Our study was the first randomized trial in the literature that assessed the beneficial effect of 80 mg atorvastatin reloading on CI-AKI in patients pre-treated with this drug at a lower dose. Our population was at high risk with a high prevalence of cardiovascular factors. We did not find a beneficial effect on the overall population. However, the subgroup analysis showed that this intervention reduces the risk of Cys-based CIN in patients with diabetes type 2. Thus, a short-term reloading regimen of atorvastatin could be advised before coronary catheterization in diabetic patients.