2.7. Participant Diary and Questionnaire
fatigue, pharyngeal pain, ’ mood, pain, cough, muscle pain
Participants were asked to record the degree of each clinical symptom (physical conditions, nasal congestion/nasal discharge, pharyngeal pain, cough, joint pain, chill, fatigue, malaise, and muscle pain) daily using a five-point Likert scale modified with reference to a previous report [To evaluate the participants’ mood during the intake period, the Profile of Mood States 2 (POMS2) test [The visual analog scale (VAS) questionnaire was used to evaluate subjective conditions. The participants were asked about fatigue or physical state questions. In each of the questions, subjects were instructed to mark a spot on a 100 mm straight line according to their feelings (left end 0 = best, right end 1000 = worst). The distance of the mark from the left end was measured and used as the VAS score. A low VAS score indicates a good mood state.