Outcomes (primary and secondary) and any changes after trial commencement
ADVERSE EVENTS, ADVERSE EFFECTS, PLAQUE
A whole-mouth average score was obtained by averaging the plaque scores of each participant at baseline (before brushing) and after brushing. Our outcome (for each participant in each treatment period) was the difference between baseline and post-brushing scores. Both self-reported non-serious oral-related adverse events and all serious adverse events were recorded in the study on the appropriate case report form. Only incidents of whole-body adverse effects were collected if they were likely associated with the product.