Introduction
bleeding, death, infertility, infection, RPOC, abortion, intrauterine tissue retention, muscle contractions
BLEEDING, POSTPARTUM HEMORRHAGE, COAGULATION DISORDERS, INTRAUTERINE ADHESION, RETAINED PRODUCTS OF CONCEPTION, INFECTION, MISCARRIAGE, COMPLICATIONS
Globally, the complications succeeding a spontaneous or unsafe abortion have been recognized as an impediment to women’s general well-being [The prevalent long-term complications of intrauterine tissue retention include infertility, bleeding, intrauterine adhesion, coagulation disorders, infection, and death, which are in a linear relationship with age advancement [Some studies have been carried out to ascertain the expulsion rate of persistent placental or trophoblastic tissue, to compare oxytocin efficacy on uterine smooth muscle contractions, and also to relate the prophylactic effects of methylergometrine on postpartum hemorrhage [This study aimed to investigate the efficacy and safety of misoprostol for treating retained products of conception (RPOC) following a miscarriage, with the added importance of avoiding hospitalization during the COVID-19 pandemic. To evaluate the efficacy and side effects of each medication regime, a comparison was drawn between the administration of misoprostol with the combined use of misoprostol plus oxytocin and misoprostol plus methylergometrine for complete expulsion of retained intrauterine tissues in patients who underwent a miscarriage. The outcome evaluated whether outpatient treatment could be substituted with a surgical approach as a safe maneuver.