Ethics approval and consent to participate
DER
In advance, the licensing Ethics Commission at the Medical Faculty of RWTH Aachen University (unabhängige Ethik-Kommission an der medizinischen Fakultät der RWTH Aachen) was consulted. They showed no apprehension about the study. They approved the experimental protocols, declaring that their vote is not required (Ethical IDs: 2019: 269/18, 2020: 270/18). We declare that all methods were carried out in accordance with relevant guidelines and regulations. Informed consent was obtained by all participants.