Study design
euthyroid
THYROID NODULE
This study included adult, euthyroid patients with a Bethesda III or IV thyroid nodule who participated in the Next, all patients underwent one [In this study, we performed a preplanned elaborative analysis of the trial data, comprising additional MD and encompassing the whole trial cohort.The research was completed in accordance with the Declaration of Helsinki as revised in 2013. The trial protocol was approved by the Institutional Review Board, the Medical Research Ethics Committee on Research Involving Human Subjects region Arnhem-Nijmegen, Nijmegen, the Netherlands, on November 10, 2014 (Ethics board approval number: 2014–1205). All trial participants gave their written informed consent before any study procedures.