Ethics approval and consent to participate
The study protocol was approved by the institutional review board of each hospital (IRB No.: E-1806/475-002, 2018-07-012, JEJUNUH 2018-07-010, J-1810-064-979, DFH19DPOS033) and all methods were performed in accordance with relevant guidelines and regulations. All patients or their representatives provided written informed consent prior to study participation. The study was also approved by the Ministry of Food and Drug Safety in Republic of Korea.