Primary, Secondary, and Exploratory End Points
depression, anxiety, depressive symptoms
SECONDARY
We performed a completer’s analysis (TreadWill was primarily designed to help individuals with depressive symptoms. Therefore, PHQ-9 was our primary outcome measure. However, as anxiety and depression are highly comorbid, we wanted to check whether the techniques presented in TreadWill also helped in the reduction of anxiety symptoms. Thus, for the experimental and the active control groups, the secondary end point was the GAD-7 score in participants who completed at least half of the intervention (3 out of 6 modules). Other secondary end points included PHQ-9 and GAD-7 scores at the 90-day follow-up.The intermediate PHQ-9 and GAD-7 scores (after every module) and 2 surveys conducted after the module 3 and the module 6 were used as exploratory end points.