Outcomes
apnea
SECONDARY
The primary outcome of this study was the length of the apnea phase until TOI decreased by 20% from baseline (assessed by NIRS). Differences between the start and stop of apnea phases were measured for PaO2, PaCO2, SpO2, and TOI (also if the primary endpoint could not be reached), BIS values, heart rate, and mean arterial pressure (MAP) were defined as secondary endpoints.At all time points (T0 to T4), blood gas samples were obtained and measured using the ABL835 Flex blood gas analyzer from Radiometer Medical (Copenhagen, Denmark).