Strengths
ASCVD
ASCVD
Our study is the first multicenter, prospective, randomized, controlled, open-label parallel-group superiority trial conducted in a Chinese population with ASCVD to explore the efficacy of mobile-based CBT on reducing LDL-C levels. The results of this study support that CBT should act as a treatment key in the comprehensive management of ASCVD. On the one hand, CBT can effectively reduce LDL-C levels in patients with ASCVD by improving self-efficacy, and the clinical benefit is more significant with the extension of the intervention time. The CBT intervention is expected to reduce the burden of lipid-lowering drugs or even replace them. On the other hand, the quality of life of patients with ASCVD improved by the CBT intervention is instant and effective. The development of mobile technology has substantially reduced the cost of CBT and increased its convenience and accessibility. Given the large number of patients with ASCVD, future work can be devoted to quantifying the economic benefits of mobile-based CBT by conducting cost-effectiveness analyses. Mobile-based CBT remains a promising option in the comprehensive management of patients with ASCVD.