Study design
The study was designed as a randomized controlled clinical trial with two parallel groups and a single-blinded approach, performed at the Periodontology Department of Cukurova University, Faculty of Dentistry (Adana, Turkey) between December 2021 and August 2022. The study protocol was approved by the Institutional Ethical Committee (03.06.2022 123/53), registered on ClinicalTrial.gov (NCT05748223-Feb 28, 2023) and performed in accordance with the Helsinki Declaration of Human Studies. Before the procedure, the patients were given full and adequate verbal and written information about the purpose of the study and written informed consent was obtained.