Treatment arms

RT (54 Gy) plus daily concomitant capecitabine 825 mg/m2 bid, followed by mFOLFOX6 or XELOX for 4 cycles (12 weeks), starting 1 week after radiotherapy ended;RT (54 Gy) plus daily concomitant capecitabine 825 mg/m2 bid, followed by capecitabine 2000 mg/m2/day for 14 days in a 21 days cycle for 4 cycles (12 weeks), starting 1 week after radiotherapy ended;