4. Discussion
postoperative pain, pain
This study evaluated the analgesic efficacy and the safety of IV ibuprofen-assisted postoperative pain in patients undergoing abdominal and orthopedic surgery. The results of this study showed that IVIB 400 mg and 800 mg not only reduced morphine consumption, compared with the placebo group, but also provided a significant reduction in pain scores at rest and with movement, both VAS and the AUCs of VAS on postoperative days 1 and 2 on the ward. Besides, the recognized AEs associated with opioid analgesia and ibuprofen did not increase significantly for the incidence of AEs between groups.