Study design
This randomized, placebo-controlled trial was carried out at the Department of Neurology, Army Medical University Southwest Hospital, from February 2019 to December 2019. The study was conducted in accordance with the guidelines and principles of the Declaration of Helsinki, approved by the Administrative Panel for Medical Research on Human Subjects (the Ethics Committee) of Army Medical University Southwest Hospital in Chongqing, China, and the trial registration number was ChiCTR1900021405 (