2.1. Study design and ethics
MAY
This study was designed to evaluate hemodynamic changes following the concomitant administration of NCD and DEX for sedation after SA in a double-blind, randomized, controlled trial. Ethical approval was obtained from the Institutional Review Board of Kyung Hee University Hospital (KHUH 2017-12-094) on March 23, 2018. The trial was conducted in accordance with the Declaration of Helsinki and registered with the Clinical Research Information Service (No. KCT0002864; registration date, May 15, 2018; principal investigator, Hee Yong Kang). The study protocol was available from the Clinical Research Information Service. Written informed consent was obtained from all participants. The study complied with the Consolidated Standards of Reporting Trials checklist.