Primary and Secondary Outcomes
death, asthma, kidney impairment, diabetes
PERIPHERAL ARTERIAL DISEASE, HYPERLIPIDEMIA, ATRIAL FIBRILLATION, ISCHEMIC STROKE, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, SECONDARY, ASTHMA, REGRESSION, HYPERTENSION, DIABETES
Data were analyzed from September 21, 2016, to July 31, 2019. We compared publicly available, weekly, CDC-reported, state-level ILI with the weekly occurrence of the primary outcome (composite of all-cause death or CP hospitalization) and secondary outcomes (death, CV hospitalization, and pulmonary hospitalization) among US participants from September 2016 to July 2019 using logistic regression models. Weekly ILI activity from 0 to 9 weeks prior to (lag 0 to lag 9) the outcome of interest was considered to assess the temporal association between exposure and outcome. Model 1 was adjusted for state, demographics (age, self-reported sex, and race) and enrollment strata (history of MI, history of hospitalization for HF). Model 2 was additionally adjusted for CV risk factors (diabetes, body mass index >30 [calculated as weight in kilograms divided by height in meters squared], kidney impairment, current smoker, peripheral arterial disease, ischemic stroke, hypertension, hyperlipidemia, asthma, chronic obstructive pulmonary disease, percutaneous coronary intervention, coronary artery bypass graft, atrial fibrillation, and implantable cardioverter-defibrillator).