Availability of data and materials
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.Ethics approval and consent to participate.This study was approved by the Ethics Committees of the Qingdao Municipal Hospital(group) (XCJJ No. 014 (fast) in 2020), and registered in the center of Chinese Clinical Trial Registry (registration number: ChiCTR2000039939, date of registration:14/11/2020.). All methods were carried out in full accordance with the Declaration of Helsinki. Informed consent was obtained from all subjects and/or their legal guardian(s).