4. Discussion
colorectal ESD
COMPLICATIONS
ESD is a well-established technique that enables en bloc resection regardless of the size and morphology of the lesion.This multicenter randomized controlled trial will evaluate the usefulness of the S-O clip in colorectal ESD by comparing the procedure time and frequency of complications with those obtained during conventional colorectal ESD. If use of the S-O clip shortens the procedure time and reduces the frequency of procedural complications, it may contribute not only to reducing the physical burden on patients, but also to shortening hospital stays and lowering costs. Although the number of facilities that can perform colorectal ESD is currently limited, safer performance of this procedure will allow it to become more widely performed. The major limitation of this trial will be that the operator will not blinded to treatment group allocation.