Outcome
Fatigue, anxiety/depression, fatigue, ’
The prospectively defined main outcome measure was the change in fatigue scores assessed using visual analog scale and several validated self-reporting questionnaires. Patients’ HRQOL was evaluated at baseline, and 1 and 6 months after FMT.Visual Analogue Scale (VAS): VAS measures fatigue intensity and consists of a 100 mm line, with two end points representing 0 (no fatigue) and 100 (extreme fatigue).Modified Fatigue Impact Scale (MFIS): This instrument provides an assessment of the effects of fatigue in terms of physical, cognitive, and psychosocial functioning consisting of 21 items. Individual scores are generated by calculating the sum of specific sets of items.15D: the 15D is a 15-dimensional instrument for measuring HRQOL among adult subjects. In each dimension, the 15D has five severity levels (1 = no problems, 5 = extreme problems/unable).EQ-5D-3L: EQ-5D-3L consists of a descriptive system, which contains five items that each represent a health dimension, including mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. In each dimension, the EQ-5D-3L has three severity levels (no, some, extreme problems/unable).