Kaplan–Meier analysis for PFS
The Kaplan–Meier analysis was performed to assess the risk factor to PFS based on the aforementioned combined model in whole cohort. Using a cutoff value of 0.587 by ROC curve, patients were stratified into the low-score and high-score groups (low-score < 0.587 predicted HAIC-response, whereas high-score > 0.587 predicted HAIC-nonresponse). The high-score patients had significantly shorter PFS than the low-score patients (Kaplan–Meier curve of the low-risk and high-risk to nonresponse stratified by the combined model in the whole cohort