Author contributions
FM, HT, ZHZ
PZ, ZNC, HB, LC, ZHZ, ZZ, and DW were responsible for initial study design. HT, SSL, HWS, YY, XCC, VM, NN, IK, FM, SH, CMBS, KI, CCCO, CD, LR, AJW, SL, WFS, FJCF, and JSC were responsible for study implementation and enrolment of participants. XXS, JJG, RC, KW, XY, SRC, and SYC were responsible for data collection and laboratory technique support. LW, LNL, RHX, KZ, JLM, and JFJ contributed to data analysis. QYW contributed to English writing. PZ, ZNC, HB, LC, ZHZ, ZZ, and DW analyzed, interpreted, and verified the data, wrote and revised the manuscript. All authors have read and approved the article.