Aim 2: Dosing Impact on Target Engagement (Analyzed as parallel-group)
SESSION
We will test dosing effects of mbNF (15-min versus 30-min condition) on change in mPFC-PCC connectivity (during MRI Session 2) from pre- to post-mbNF. Models will be similar to Aim 1, with an added time (0 = pre-mbNF, 1 = post-mbNF) x dose (15-min versus 30-min condition) interaction term to test differential effects of dosing on pre-post change as follows: