Patient recruitment
bone loss
CHRONIC PERIODONTITIS, SYSTEMIC DISEASES, BONE LOSS
After a screening visit including a full-mouth periodontal and radiographic evaluation, all patients fulfilling the following criteria were asked to participate.The inclusion criteria were as follows:• Age between 18 and 80 years• Systemically healthy• Diagnosis of chronic periodontitis based on the presence of at least 4 teeth per quadrant with PD>4 mm and radiographic bone loss between 30 and 50% in more than 30% of teeth [The exclusion criteria were as follows:• Systemic diseases requiring antibiotic prophylaxis or other systemic medication that could affect the patient’s clinical response• Periodontal treatment within the last 12 months or systemic antibiotic intake in the last 3 months• Pregnant women or those planning to get pregnant in the next 6 months