Conclusion
tumor
TUMOR
In conclusion, our pilot study showed that patients with irresectable nGBM showed high willingness to participate in a randomized study investigating LITT in comparison to standard of care, with good adherence to the study procedures. The study protocol was feasible and initial safety data appear acceptable when compared to craniotomy for tumor resection. To study the effectiveness of LITT in patients with nGBM a larger trial is needed. The outcomes of this pilot study helped to further refine the design of multicenter RCT, which is currently recruiting patients in the Netherlands.