Ethics approval and consent to participate
Each Intervention site (University Copenhagen (Denmark), University of Helsinki (Finland), University of Nottingham (United Kingdom), University of Sydney (Australia), University of Maastricht (The Netherlands), Medical University of Sofia (Bulgaria), University of Navarra (Spain), University of Auckland (New Zealand)) obtained the ethics approval from their ethical boards according to institutional and national requirements and guidelines. All data reported in this study were collected following the approved protocols. All study participants were required to provide a written informed consent before participation. All information and consent forms were provided in local languages.