2.3. Cigarette, E-Cigarette, and HTPs Increased Inflammation Values
In the hsCRP ELISA determination, there is a significant increase in the paired t-test of the cigarette (In the evaluation of the IL-6 ELISA, a significant increase (IL-6 determination by multiplex immunoassay, in contrast to ELISA determination, shows a significant increase for cigarette, e-cigarette (JUUL), and IQOS (The multiplex immunoassay showed a significant increase for IL-2 determination in the experimental arms of the e-cigarette (JUUL), IQOS, and nicotine-free e-cigarette (Determination of IL-4, CSF, IFN, and IL-10 failed to detect significant changes for any of the devices in the multiplex immunoassay.