Urinalysis Results Over Time
Data represent the mean percentage (standard error of the mean) of urine samples tested immediately onsite for evidence of cocaine use as a function of study week (range, weeks 0-30), with missing data treated as missing. Time periods represent weeks 1 to 6 (double-blind placebo lead-in period), 7 to 26 (active pharmacotherapy with incentives), and 27 to 30 (pharmacotherapy-only follow-up period). Top panels present data for bupropion slow release (SR) and placebo among A, the modified intention-to-treat (MITT; defined as ≥1 dose of study medication) and B, completer (defined as being present during the final study week) samples. Urine results as a function of incentive groups abstinence initiation (AI) and relapse prevention (RP) are presented within each medication condition for C, MITT and D, completer samples.