Acute alterations of mind, measured by the Five Dimensions of Altered States of Consciousness (5D-ASC) and the Mystical Experience Questionnaire (MEQ).
DRUG EFFECT
The high 500 mg mescaline dose, LSD, and psilocybin induced comparable subjective effects on all subscales. The low 300 mg mescaline dose induced lower effects than all other drug conditions. Placebo scores did not reach the visualization threshold. The data are expressed as the mean ± SEM percentage of maximum scale scores in 32 participants for LSD and psilocybin and in 16 participants for each mescaline dose. The corresponding statistics are presented in Supplementary Tables SDescriptive parameters for the acute subjective response curves (VAS “any drug effect” over time) for each substance are shown in Table Characteristics of the subjective response to Mescaline, LSD, and Psilocybin.Parameters are for “any drug effect” as determined using the individual effect-time curves. The threshold to determine times to onset and offset was set to 10% of the individual maximal response. Values are mean ± SD (range). *