Patients
Cognitive Impairment, critically ill, head injury, cognitive dysfunction, skull defects, TBI, cardiovascular and cerebrovascular diseases
DISORDER, CRITICALLY ILL
From September 2017 to September 2019, 105 VS patients with a consciousness disorder were recruited for this study from the Department of Neurosurgery, Intensive Care Unit (ICU), and Rehabilitation Department of the First Affiliated Hospital of Jinan University. According to the random number table, they were divided into a test group, control group and placebo group at a ratio of 1:1:1 in a sealed envelope. A total of 6 patients withdrew due to personal reasons and were unable to continue hospitalization (drop‐out rate 5.7%). A total of 99 patients completed the trial: 33 in the experimental group, 33 in the control group, and 33 in the placebo group. The experiment adopted a double‐blind method; that is, the randomized patients or their family members were unaware of whether they were in the experimental group or the control group, and the rTMS operator was also unaware of the trial design.The inclusion criteria were as follows: (1) all patients met the diagnostic criteria for TBI and cognitive dysfunction based on the Chinese Guidelines for Diagnosis and Treatment of Vascular Cognitive Impairment (Wang, The exclusion criteria were as follows: (1) individuals were critically ill and had unstable vital signs; (2) individuals had intracranial indwelling metal objects, cranial bone flaps, and skull defects; (3) patients who had a history of head injury or cardiovascular and cerebrovascular diseases.