Introduction
systemic thromboembolism, stroke, NVAF, bleed, Atrial fibrillation
STROKE, BLEED, CARDIAC ARRHYTHMIA, ATRIAL FIBRILLATION, COMPLICATIONS
Non-valvular Atrial fibrillation (NVAF) is a common type of cardiac arrhythmia, related with an increased risk of systemic thromboembolism [Traditionally, warfarin was a primary treatment protocol of stroke prevention in AF patients. However, it has some disadvantages, such as, high-risk to bleed, susceptible to food and drugs interactions, narrow range of effective doses and frequent need of INR testing. The novel oral anti-coagulants(NOACs) are recommended by most AF guidelines as the first-line stroke prevention medications due to its safety and efficacy [The long-term outcome of LAAC in Chinese AF patients are still lacking. Our bidirectional (prospective, retrospective), single-center study was designed to investigate the long-term outcomes after percutaneous LAAC in patients with NVAF in a registry in mainland China. Periprocedural success and complications were also collected.