Study cohort
SARS-CoV-2 infection
SARS-COV-2 INFECTION
Healthcare workers without previously diagnosed SARS-CoV-2 infection and without the use of immunosuppressive drugs for any diagnostic from Clínica Santa María; Santiago, Chile and patients belonging to the transplant unit of the Clínica Santa Maria, Santiago, Chile were invited to participate in this study. Forty-five solid organ transplant recipients, 42.2% (19) women, with a mean age of 52 years (IQR 37-59) at the start of vaccination, were recruited. The transplanted organs were distributed as follows: 12 pulmonary (6 monopulmonary), 9 liver, 1 heart, 12 kidney and 11 kidney-pancreas transplants. More detailed information about the characteristics of the transplanted patients is shown in Characteristics of study subjects.All participants signed informed consent before any study procedure was undertaken and protocols were approved by the respective Ethics Committee at Clínica Santa María (No. 132604-21) and Facultad de Medicina at Universidad de Chile (No. 0361-2021). Serum samples were collected between June 2021 and February 2022.