2.5. Interventions and Outcomes Measurement
OI
SECONDARY, OIS
After preliminary screening of personal medical history and oral examination at baseline, the participants were randomly assigned to one of the intervention groups: the toothbrush + oral irrigator group (test group) received an OI (WaterPikBefore every clinical examination, all participants were instructed to refrain from oral hygiene for 12 h and fast for solids and liquids for 2 h. A single trained examiner evaluated all gingival inflammation-related indices. The MGI [Participants returned to the clinical research center for dental examination at 4 weeks ± 3 days, 8 weeks ± 3 days, and 12 weeks ± 3 days after baseline examinations. The T-QH and gingival inflammation-related indices, including MGI, BI, and BOP%, were reevaluated. Furthermore, the safety indicators were also recorded. The modified Bass technique and the method of OIs use were reinforced at each visit by the same dental assistant. The primary outcomes were gingivitis-related indices after 12 weeks of using OIs. The secondary outcomes were plaque-related indices and gingivitis-related indices at 4 weeks and the safety indicators.