Study design
STEMI
This study consists of a post-hoc analysis of the RIC-STEMI study (NCT02313961) [This trial aimed to assess the superiority of RIC (3 cycles of inflation and deflation of a left lower limb cuff, for 5 min each) over PPCI in all-comer patients presenting with STEMI between March 2013 and December 2015. Eligible patients were at least 18 years old and were admitted to the emergency department of Braga Hospital with putative STEMI [To perform this study the authors consulted the database of RIC-STEMI study. This analysis included 448 STEMI patients previously randomized to either PPCI alone (PPCI group) (The cardioprotective effect of RIC was compared within isolated PPCI, according to the period of the day in which it was performed. Figure Study flow diagramThe admission echocardiography was performed in the first 24 h of hospitalization. The median month to measure the follow-up ejection fraction was 10 (IQR 1.8) months.