Sample size
The cure rate of single-dose albendazole for hookworms varies between 36% and 93% in previously reported studies [With type I error probability of 5%, 100 participants in each comparison group were required for 90% power to detect a difference in cure rate of 95% versus 80%. Therefore, the total target sample size for the trial was 186. In order to allow for 5% loss to follow-up, the target sample size was increased to 210.