Secondary outcomes
obesity, Obesity, psychiatric, insufficiency
DISORDER, OBESITY, OBESITY, BLOOD

E. Emotional and behavioral problemsThe Dutch parent-report version of the Child Behavior Checklist 6–18 years (CBCL) assesses a wide range of children's emotional and behavioral problems, aiming to identify children at high risk of a psychiatric disorder [F. Cognitive performanceThe Cognitive Task Application (COTAPP) measures cognitive performance [G. Somatic measurementsPhysical examination includes measurement of weight, height, blood pressure, heart rate, head circumstances, an inspection of dysmorphic features, and moto coordination are routinely assessed at start of treatment (T0) by a nurse specialist supervised by a child and adolescent psychiatrist as part of standard clinical care. A subset of the somatic screening (height, weight, waist circumference, blood pressure) is assessed at T1 and T3.Overweight and obesity prevalence for children are defined by the cut-off values on body mass index references and age according to the International Obesity Task Force [H. Blood laboratory testsBlood samples (15 ml) are assessing glucose, HbA1C, total cholesterol, lipid profile, prolactin, vitamin D, thyroid stimulation hormone, and ALAT at T0 (Baseline) and for children with abnormalities during treatment , which are processed at local laboratory facilities. References from these facilities are used to interpret the results of the laboratory findings. For vitamin D, references from the American Academy of Pediatrics Committee on Nutrition and The Institute of Medicine are used corresponding to a serum 25-hydroxyvitamin D level of at least 50 nmol/liter (e.g., insufficiency <50-75 nmol/ml; deficiency <50nmol/l) [