Study Design
Epilepsy
EPILEPSY, MOVEMENT DISORDERS
The Medtronic Registry for Epilepsy (MORE) registry is an open-label, observational, international study that collected both prospective and retrospective data to evaluate the long-term therapy effectiveness, safety, and performance of a neuromodulation system for ANT DBS for the treatment of DRE. The study was designed to characterize patients implanted with DBS, identify factors predicting response to the therapy, and explore potential trends affecting changes in the SF. Patient-reported outcomes, including HRQOL and cognitive performance, were also assessed. Sites were selected partly based on their documented previous expertise with resective surgery for DRE, with DBS in other indications such as movement disorders, and access to a patient pool of sufficient potential to recruit patients meeting inclusion criteria.