Statistical analysis
death
REGRESSION, EVENT, SECONDARY, CVD
The primary analysis will be based on participants' randomization assignment regardless of their achieved BP levels (intention‐to‐treat analysis). Follow‐up time will be calculated from the date of randomization to the date of the event ascertainment for patients with event occurrence, the date of the trial completion for patients without event occurrence, the date of death for patients who died during follow‐up, or the date of last contact for patients lost to follow‐up. Cox proportional hazards regression will be used to compare the time from randomization to the first CVD event between the randomization groups with two‐sided tests at the 5% level of significance. The model will include an indicator for intervention as its sole predictor variable. Study center at randomization will be a stratifying factor.Tests of secondary outcomes will be conducted with models similar to those used in the primary analysis. These will be reported with 95% CIs and nominal 