Limitations
pain
The current study has a number of limitations that should be taken into consideration when interpreting the results. The within-subjects design is statistically powerful and allows each participant to be compared for the different treatments, but has the drawback that in the current study, participants, care provider and primary outcomes assessor remain aware of the different treatment conditions, and this awareness has the potential to influence the resultsAnother limitation is that the current study is an analog experimental pain study, with only very brief thermal pain stimuli and brief VR treatment durations. Whether the current results generalize to clinical settings (e.g., for brief venipunctures