Incidence of Major Events Related to First Occurrence of Stroke and Major Bleeding
stroke, hemorrhagic, ischemic strokes, extracranial hemorrhage
INTRACRANIAL HEMORRHAGE, EVENTS, ISCHEMIC STROKES, STROKE
HR indicates hazard ratio.Absolute numbers of hemorrhagic and nonhemorrhagic events were small. Among 1000 individuals taking 100 mg/d of low-dose aspirin over 5 years, there were 2.5 fewer ischemic strokes at the expense of 3.5 cases of intracranial hemorrhage, a finding that did not meet the threshold for statistical significance. No difference would be expected for overall stroke incidence or stroke mortality. Major extracranial hemorrhage (