Handling of missing data
BPD, death
SECONDARY
The primary analysis will be based on an intention to treat population accounting for all infants randomized. If necessary, multiple imputation methods will be used for missing data; however, it is expected there will be very few instances in which the primary outcome cannot be determined. The reason for this is that infant death is always recorded and BPD assessment at 36 weeks will likely occur for nearly all infants when they are still in the hospital and their outcome can be recorded directly into the trial database. Therefore, we do not anticipate needing to address missing data for the primary or secondary outcomes in this study.