Summary of main results
SUI
PAD, LEAKAGE
The responders to the HCST showed a good understanding across the two questions of the HCST, with minimum conflicting values.The Cronbach’s alpha analysis revealed strong consistency between the two sets of HCST results repeated 24 h apart (> 0.7). This allowed the measurement error to be calculated for more rigorous study. It was an important confirmation of reliability, since a measure is only precise if it remains consistent across repeated measures.The comparison of diagnostic accuracy between the HCST to the 24- hour pad test (for positive/negative values), had recurring high levels of sensitivity, specificity, and NPV to show diagnostic accuracy. The high sensitivity indicates when SUI is present; the majority of cases were detected. The > 0.7 specificity credibly shows that the HCST identified those without SUI. The NPV, representing the identification of negatives, was the strongest parameter of HCST diagnostic accuracy.In contrast, the PPV had lower results (across the timepoints except at baseline). The HCST would therefore be at risk of introducing false positives. There are a number of potential explanations to this poor PPV. Both the PPV and NPV can be influenced by the prevalence of a condition. The data for this study was from a RCT [In the adjusted model, those reporting Moderate and Large leakage on the HCST diagram had significantly heavier pads on the 24-h pad test. The two tools therefore shared a good level of agreement. The pad weights increased further for those with moderate to severe urgency (see Appendices A 'Small improvement' (≤ 1 group) on the HCST was not associated with reports of 'Much better/Very much better' symptoms on the PGI-I (successful outcome). This is in keeping with how ‘A little better’ on the PGI-I scale was not considered as a successful outcome post-surgery. However, a 'Big improvement' (≥ 2 groups) was significantly associated with a successful outcome on PGI-I. The HCST has therefore been able to detect the participants’ reported success on PGI-I.