2.9. Complete Blood Cell Counts
Complete blood cell counts were measured in freshly collected EDTA whole blood by Quest Diagnostics by electronic cell sizing/counting/cytometry/microscopy. Data reported include total white blood cell counts and differential absolute and % neutrophils, lymphocytes, monocytes, eosinophils, and basophils. Additional hematologic parameters reported include total red blood cells, total hemoglobin and hematocrit, mean corpuscular volume and mean corpuscular hemoglobin concentration, and platelet concentrations. Clinically-relevant immune ratios, including neutrophil:lymphocyte and lymphocyte:monocyte ratios were calculated as follows: neutrophil:lymphocyte ratio = absolute neutrophils ÷ absolute lymphocytes; lymphocyte:monocyte ratio = absolute lymphocytes ÷ absolute monocytes [