Results
fatigue, CRF, breast cancer
RECRUITMENT, METASTASES, CRF, BREAST CANCER
Based on 278 breast cancer screened patients, 126 breast cancer patients with chronic CRF without metastases were included in the study from June 2011 to March 2013. Of those, 65 participants were randomized to 1 of the 3 treatment arms and 61 who refused randomization were allocated by preference (AT: 22 randomized/6 by preference; MT: 21/23; CT: 22/32)Flowchart of recruitment. Course of the CFS-D for the 3 study groups (aerobic training: red; multimodal therapy: blue; combination therapy: violet) over 4 years (n = 79), including after 10 weeks of intervention (T1) and 6 months later (T2) in frail color (n = 79). Colored asterisk indicates significant less fatigue in MT versus AT. Course of the PSQI for the 3 study groups (aerobic training: red; multimodal therapy: blue; combination therapy: violet) over 4 years (n = 79), including after 10 weeks of intervention (T1) and 6 months later (T2) in frail color (n = 79). Colored asterisk indicates significant better sleep quality in MT and CT versus AT. 