MRI
APPENDIX
A subset of participants, representative of the full group, at both trial sites completed a neuroimaging session at baseline and 12 mo. Here, we report volumetric measures of brain structure in this neuroimaging subset derived from T1-weighted anatomical scans acquired at both sites. Further imaging modalities acquired in this neuroimaging subset are to be reported elsewhere and are detailed in Appendix F of the trial protocol paper [T1-weighted images were processed following the longitudinal processing pipeline [