Subgroup analysis
PD, disability
To determine the connection between gut microbiota and PD symptoms after FMT treatment, we further studied the effect of FMT on PD by dividing participants in the FMT group into responder and non-responder subgroups, as the exploratory and ancillary analyses. According to the change in the MDS-UPDRS Part 2 score, which is the Motor Experiences of Daily Living (M-EDL) score used for measuring the changes in the level of disability of patients with PD, patients with a decrease in MDS-UPDRS 2 score larger than 3.05 were considered FMT responders, while the rest were deemed non-responders based on previous reports on minimal clinically important differences in MDS-UPDRS 2 scores.