Inflammation: IL-6
inflammation
INFLAMMATION
We finally analyzed the trend in IL-6, chosen as the most important cytokine related to onset and maintenance of inflammation. Because of the trend seen with the CD4+ and CD8+ TM/EMRA T cell subsets (large difference by study arm at T6 followed by an attenuation of the difference at T12), we hypothesized that this might have been caused by a return to normal in the overall level of inflammation at T6. However, the data carried no evidence of a difference in the trajectories of IL-6 over T0-T12 by study arm, and especially the difference by arm in IL-6 tended to remain small and stable over T6-T12 (IL-6 by study arm—adjusted analysis.
RCT, randomized clinical trial; VL, viral load.

