Background
Obesity, obesity, weight loss, metabolic abnormalities
OBESITY, OBESITY
Obesity and its associated metabolic abnormalities have become a major public health challenge worldwide. From 1993 to 2015, obesity (BMI ≥ 27.5 m/kgDietary interventions have been proven to be an effective method for weight loss [In this study, we aimed to conduct a 12-week randomized controlled trial to compare the contribution of the weight loss effects of a calorie-restricted diet alone (low-calorie, high-to-moderate carbohydrate) with that of a low-carbohydrate diet alone (low-carbohydrate, without calorie restriction). We also evaluated whether the combination of dietary carbohydrates and calorie restriction could augment weight loss and improve the metabolic risk factors in overweight/obese individuals.