Statistical analysis
Normal distribution was decided by D’Agostino-Pearson omnibus normality test.Continuous variables were expressed as mean (standard deviation) and categorical variables were presented as n (%).Intragroup comparation was evaluated by paired t test or Wilcoxon Signed Rank test for normally distributed and non-normally distributed continuous variables,respectively. Numerical differences between two groups were assessed by unpaired t test or Mann-Whitney U test for normally distributed and non-normally distributed continuous variables, respectively.Changes in allergen species and SPT results were assessed by Fisher’s exact test or Pearson chi-square test. The threshold for significance was P<0.05. All statistical analyses were conducted using GraphPad Prism software, Version 9.0 (GraphPad Software, San Diego, California, USA).