Randomization and blinding
Based on a computer-generated random sequence, participants were randomly assigned, on a 1:1 ratio, to an intervention, SOC group or a control group (receiving usual care). To maintain allocation concealment, we ensured that only the intervention nurse had access to the random sequence. Physicians and staff at the study sites were aware of a pending nursing-intervention study but were blinded with respect to the hypothesis, group allocation, specific SOC protocols, and study endpoints. Moreover, outcome assessors were blinded to the group assignments, ensuring an unbiased evaluation.