Introduction
SECONDARY
Voriconazole is a second-generation triazole antifungal drug synthesized artificially. Although its structure is similar to that of fluconazole, its antibacterial efficacy is improved [This is a randomized, open, two sequence, two cycle, crossover clinical study. The main purpose of the study was to evaluate the bioequivalence between experimental formulation and the reference formulation (Vfend ®) at 4 mg/kg and 6 mg/kg doses. The secondary purpose of the study was to compare the safety of the two formulations.