Data availability
Pseudonymized participant data, including baseline characteristics and results of primary and exploratory endpoint analyses reported in this article, can be shared in compliance with current data protection regulations by the European Union. Data sharing requires a current and positive vote by the requestor’s competent ethics committee. All proposals should be directed to the corresponding author. The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the datasets identifier (1) 