Methods
The study was approved by the local ethical committees of participating centres (Swedish Ethical Review Authority: 2019-05948; Regional Committees for Medical and Health Research Ethics, REK sør-øst D: no. 93484; Bioethics Committee of Jagiellonian University: 1072.6120.286.2019; Ethical Committee City of Vienna: EK 21-172-0821). The study was registered with ClinicalTrials.gov (NCT04509011).Patients referred to participating departments who could be included in the study received written and oral information. Informed written consent was obtained from all study patients.