Author contributions
RECRUITMENT
B.R.L., W.X.G., and J.W. conceived and designed the study. B.R.L., W.X.G., J.W., and H.T.Y. were responsible for patient recruitment. Q.L., J. Yang, Y.Y., C.Z., and N.Q.D. were responsible for patient treatment and patient care. X.F.L., M.W., L.M.Z., and P.Z. were responsible for surgery. X.S.F., Y.F., L.L., and F.C.L. helped with pathological evaluation. S.L. helped with image evaluation. J. Yan was responsible for quality control of radiotherapy. X.Y.Z. collected the data. Y.Z. and J.W.Z. analyzed and interpreted clinical data. H.C., S.Q.C., and X.C.Z. were responsible for biomarker analysis. JW wrote the first draft of the manuscript.