Sample size and statistical methods
This is a hypothesis‐generating feasibility study; the collected data and information are supposed to identify the safety and treatment responses, and to calculate a preliminary sample size for a randomized controlled trial. We chose to include a total of eight patients in this trial. Data were analyzed using the SPSS version 25 (IBM, Inc., Chicago, IL). One‐way ANOVA is used for analysis of VAS score in different time points, and a two‐way ANOVA is applied for analysis of VAS score with variables of time and skin position. A 