Anti-hypertension effects of pomegranate peel
fibrosis, decrease in systolic and diastolic blood pressure, weight gain, metabolic syndrome, lipotoxicity
METABOLIC SYNDROME, INSULIN SENSITIVITY, FIBROSIS
In our study, systolic and diastolic blood pressure were evaluated at baseline, midpoint, and endpoint of the intervention. The pomegranate peel group showed a significant decrease in systolic and diastolic blood pressure even after adjusting for potential confounding factors.Khadem-Haghighian et al. [
Effects of pomegranate peel on metabolic syndrome risk factors. In this figure, the anti-oxidant, anti-inflammatory, and prebiotic effects of pomegranate peel are illustrated. PP as a prebiotic leads to the production of short-chain fatty acids (SCFA), the reduction of lipopolysaccharides (LPS), and the regulation of GLP-1 secretion. On the other hand, PP resulted in reduced inflammatory pathways and regulated lipolysis and insulin sensitivity. Together, they cause lower cholesterol and blood sugar levels, as well as lower fibrosis in the liver. Also, PP as an antioxidant leads to lower lipotoxicity and regulated lipid-related hormones such as leptin and adiponectin which all result in lower lipid globules in the liver and reduced appetite as well as weight gain