Subjects
From January 2018 to February 2020 we enrolled 19 patients between 20 to 70 years of age presenting to the outpatient endocrine clinic at the University Hospital Basel, Switzerland. Patients were eligible if the TSH value was below 0.2 mlU/l and the level of free T4 at or above 25 pmol/l or free T3 at or above 8 pmol/l. Patients with a BMI above 30 kg/mThe study protocol was reviewed and approved on December 11, 2017, by the medical ethics committee of the University of Basel (ID EKNZ 2017-02044) and registered on ClinicalTrials.gov (NCT03379181). All participants provided written informed consent.