Evaluation of glycocalyx
No significant differences in PBRs were observed between the groups at the beginning of the study. However, a significantly lower PBR was found in the AA group in capillaries of the 5–9 μm diameter group immediately after the first ascorbic acid infusion in the AA group compared with placebo: 1.07 (1.05–1.16) μm vs. 1.18 (1.15–1.22) μm, p = 0.015 (Fig. 
Changes of PBR in 5–9 microns diameter vesselsAA—ascorbic acid; PBR - perfused boundary region; * p < 0.05 between groupsData are presented as median and 25th and 75th percentiles