Change in blood flow velocity (V-test)
POSITIVE
The mean (standard deviation) blood flow velocity at the baseline and post-injection phase were as follows: 16.5 (4.2) and 21.3 (5.4) for 0.1 mL/kg (p < 0.001); 16.3 (3.5) and 22.6 (5.0) for 0.3 mL/kg (p < 0.001); and 16.4 (3.9) and 23.1 (4.4) for 0.5 mL/kg (p < 0.001), respectively. The proportions of positive V-tests for each dose group were 81.5% (0.1 mL/kg), 91.3% (0.3 mL/kg), and 93.0% (0.5 mL/kg) (Positive results in the V-test for each dose of normal saline.CI, confidence interval; OR, odds ratio; V-test, blood flow velocity test.