Anaesthetic depth and burst suppression
TAVR
EVENT
BIS values could be recorded continuously in 113 patients (56 male and 57 female). Average BIS was 44.5 ± 6.5. The study protocol demanded that the BIS should be between 60 and 40. However, BIS episodes below 40 for ten seconds or more could be detected in 109 (96.5%) patients (Table BIS values for all patients and for patients with or without PODBIS values could be obtained from 113 patients. The average BIS, the mean of the lowest BIS values as well as the number of BIS phases below 40 during each anesthesia did not differ between patients with and without POD. The relative proportion of BIS phases and the rate of burst suppression was not statistically significant between patients with POD or not, statistical significance with *p < 0.05Of the 118 patients included in the study group, 60 patients (32 female and 28 male) were exposed to the tape and 58 (29 female and 29 male) were randomized to the placebo group and listened to the empty tape. None of the patients reported of conscious recollection of any event during the TAVR procedure. In each group, 8 patients developed POD. There was no statistically significant difference in POD between the patients who were in the treatment or in the placebo group (p = 0.577).