Bone turnover markers
The bone formation marker N-terminal propeptide of type-1 collagen (P1NP) was significantly decreased in both arms at week 24 (In individuals allocated in the TAF arm we detected a positive correlation between changes in weight and changes in bone quality BMSi (Spearman Rho’s 0.510;p=0.021) after 24 weeks of follow up.Significant changes in 25-OH vitamin D