Inclusion and exclusion criteria
IBS, depression, IBD, allergies
DISEASES, INFLAMMATORY BOWEL DISEASE, ALLERGIES
Patients without gender or age limitations with a diagnosis of IBS based on ROME IV criteria (1) without any prior confirmed GI diseases such as inflammatory bowel disease (IBD), (2) without any prior GI surgery, (3) without any history of depression, (4) without using any medications affecting sleep, and (5) without any history of using dietary and herbal supplements, were included. Patients with allergies, side effects, or compromised adherence to the treatment were excluded during the trial.