Introduction
DISEASE
Physiology is one of basic medical sciences that studies the phenomenon and laws of human life activities, which provides a basic understanding of how the human body functions under conditions of health and disease [In recent years, the flipped classroom method to teaching has received increasingly attention in health profession education. Flipped classroom is a new educational approach invented under the background of “internet+”, which is referred to a “student-centered” pedagogical model in which classroom and self-study time are reversed [As the benefits of flipped classroom includes better self-regulated learning skills, more effective student-teacher interactions, and increased learner engagement and motivation [Consequently, in this study we report and describe the implementation and delivery of a student-centered flipped classroom methodology for the whole of physiology course in medical undergraduate students. The purpose of current study was: (1) to investigate the effectiveness of flipped classroom on physiology knowledge and skill-set acquisition as measured by usual performance and final exam score, and to determine the effect of flipped classroom model on the formative assessment system; (2) to assess the student’s perceptions of the flipped approach after course completion.