Effects of COVID-19 on allergic symptoms and treatments
allergic symptoms, allergic, OLP
Since a part of our sample was included before the pandemic onset in 2020, we were able to compare the allergic burden in general as well as the impact of placebo treatments before and during (or end of) the pandemic. Results demonstrated that patients showed significantly stronger allergic symptoms prior to the pandemic (for CSMS, TNSS, and RQLQ, considering all four arms of the study). Moreover, we found that the impact of the OLP treatment was also greater before the pandemic (see Tables Comparison of allergic symptoms before and after the COVID-19 pandemic (baseline data; bold data marks significant results, Wilcoxon tests, including all 4 arms of the study, N = 89).Comparison of OLP effects before and after the COVID-19 pandemic (change scores, bold data marks significant results, Wilcoxon tests, N = 22 (OLP group only)).