Ethics approval and consent to participate
All methods were carried out in accordance with relevant guidelines and regulations. Ethical approval for study was obtained from second Affiliated Hospital of Nanchang University Medical Research Ethics Committee. Informed consent was obtained from all the participants.We declare that none of the work contained in this manuscript is published in any language or currently under consideration at any other journal, and there are no conflicts of interest to declare. All authors have contributed to read and approved this submitted manuscript in its current form.