Prioritisation process
All eligible research questions were entered into a three-round eDelphi survey using ‘DelphiManager’ (Comet Initiative Delphi Manager, University of Liverpool, UK) software, to establish a consensus as to their importance. Participants were asked to rank each research question on a 9-point Likert scale with 1 representing ‘no importance’ and 9 representing ‘critical importance’. After completion of round one, participants could suggest additional questions in PICO format which underwent the same review process as existing questions and were added to the second round of the eDelphi. Due to the large number of research questions, the second and third rounds of the eDelphi were limited to the top 75 and 50 ranked questions, respectively, to help minimise attrition rates. In the third round, the ranking by individual stakeholder group was displayed using the DelphiManager software (
