2. Case study: MUSCIAN trial
chronic pain, CWP
CHRONIC PAIN
To illustrate the methodology presented in this paper and demonstrate the use of the R-package The MUSICIAN study was a 2x2 factorial trial that estimated the clinical effectiveness and cost-effectiveness of remotely (by telephone) delivered cognitive-behavioral therapy (tCBT), an exercise program, and a combined intervention of tCBT plus exercise, compared with treatment as usual (TAU) among people with CWP. For a complete discussion about the study and setting, we refer to [Previous analysis of the MUSICIAN trial data has shown a significant benefit of tCBT in people with chronic pain as compared to treatment as TAU [