Cytokine quantification
The target cytokines were measured in plasma samples collected from the participants at baseline and follow‐up (Week 12) using three single‐plex assays (i.e., CRP U‐plex; SPARC and FGF21 R‐plex) and two multiplex assays (i.e., IL‐1b and TNF‐a U‐plex; IL‐6, IL‐8, IL‐10, IL‐13, IL‐15 and IL‐18 U‐plex) from Meso Scale Discovery (Rockville, MD, USA) following the manufacturer's instructions and as previously published (Garneau et al., 