DISCUSSION
pulpitis, tooth type, pain
PULPITIS, CYTOTOXICITY, SYMPTOMATIC APICAL PERIODONTITIS, PULP NECROSIS
This study aimed to compare the severity of pain after the endodontic treatment in mandibular molars with irreversible pulpitis following the use of NaOCl irrigant at different temperatures and concentrations in a randomized, double‐blind clinical trial.In the present study, the 10‐cm VAS was used to measure pain, and patients received the necessary training to record their pain scores in the postoperative period (Moher et al., In this study, changes in VAS pain levels over time were significant in all the groups. According to Table NaOCl has dose‐dependent antimicrobial and tissue dissolution effects, which improve at higher concentrations; however, under these conditions, its cytotoxicity increases (Parirokh et al., Farzaneh et al. (Verma et al. (Flare‐up pain is associated with pulp necrosis, symptomatic apical periodontitis, and periapical radiolucency after treatment (Walton, According to Table Gundogdu and Arslan (Keskin et al. (Overfilling material is associated with more pain following endodontic treatment, according to Demenech et al. (Different preoperative and intraoperative variables (e.g., age, sex, tooth type, the severity of pain, number of visits, type of the irrigation solution, canal preparation technique, sealer type and the analgesic used) have been shown to influence the pain severity following endodontic treatments (Arias et al., One of the limitations of this study was the small size of it and only 12 patients were excluded from this, but we conducted this study based on the time we had and the patients who met the inclusion and exclusion criteria. We hope that studies with more participating patients will be conducted in this field in the future. In this study, in unsuccessful anesthesia, PDL and intrapulpal injections were used as complementary techniques, which is likely to reduce posttreatment pain in these patients. This study used low NaOCl concentrations to reduce cytotoxicity, which may contribute to the lack of pain difference between groups. It would be better to study other concentrations in future studies to determine its effect on pain. Our study selected patients who did not take any painkillers 12 h before the treatment, despite most of them having moderate pain before the treatment. It would be more useful to examine the effects of painkillers and not taking painkillers before the treatment on posttreatment pain in future studies.