Ethics approval and consent to participate
The study was performed in accordance with the declaration of Helsinki. Ethical approval for this study (2021-03-031-K01) was provided by the Institutional Ethics Committee of the Affiliated Jiangning Hospital of Nanjing Medical University. The registration of this study was approved in the Chinese Clinical Trial Registry on 5/30/2022 (CTRI registration number—ChiCTR2200060387). All volunteers involved were informed of the proposal and gave their written, informed consent.