Evaluation parameters
pain
The following measures were recorded:Remaining wound area (RWA): Defect area was measured straight after operation and after 7, 14, and 28 postoperative days. For this, photographs standardized for brightness, distance, and angle were taken (Nikon D3500, Nikon Inc., Minato, Japan). A scale was used as a reference to measure this area. These photographs were exported to an image software (ImageJ—NIH, Bethesda, USA), and the wound area was measured in square millimeters [Tissue colorimetry (TC): Tissue color similarity of regions adjacent to the operated area was analyzed through photographs. The photographs were exported to an image software (ImageJ—NIH, Bethesda, USA), and two areas, one from the wound and another adjacent, were used. Color difference (ΔE) of the areas was evaluated using brightness parameters (L), red-green chroma scale (a), and yellow-blue chroma scale (b) according to the following equation [Postoperative discomfort (D): Through air spray for 5 s over the operated site, sensitive function was measured at 7, 14, and 28 days after surgical procedure. After air spray application, patients were required to use a visual analogue scale (VAS) of 100 mm to assess discomfort; scale extremes were “no pain” to “extreme.” In addition, patients were asked to report the number of analgesics taken during the first week [