Acetyl-L-Carnitines
atherosclerosis
OXIDATIVE STRESS, ATHEROSCLEROSIS
Another upregulated lipid group after the 12 week VLCHF diet was Acetyl-L-Carnitines (ALC). ALC is a natural derivate of carnitine and can be found in various mammalian tissues, particularly in liver and skeletal muscles. Carnitine and its derivates play an essential role in the intermediary metabolism of glucose and β-oxidation of long-chain fatty acids. As a widely diffused dietary supplement, ALC may have a potential for the prevention of the oxidative stress (Lopez-Maldonado et al., It has been shown in animal models that ALC inhibits the development of atherosclerosis by regulating blood lipids and inhibiting the gene expression of inflammatory factors and oxidative stress (Wang et al., 