Statistical analysis
REGRESSION
Patient demographic, clinical, and laboratory data are described using (1) the mean (±SD) or median (range), depending on the underlying distribution, for continuous variables and (2) frequencies (percentages) for categorical variables. Continuous variables were compared using analysis of variance, while categorical variables were compared using the chi-square test. A mixed linear regression model was applied to assess the potential changes in laboratory data among the groups and various visit time points, and the intercept was random. The reported 