Author contributions
Yan Li and Dong Han are co-first author. Yan Li, Dong Han and Xiaoyi Duan contributed to the conception of the study; Yan Li and Cong Shen, performed the experiments; Yan Li, Cong Shen and Dong Han contributed significantly to analysis and manuscript preparation; Yan Li, Dong Han and Xiaoyi Duan helped perform the analysis with constructive discussions.