Adverse outcome-free survival
ascites, cirrhosis, PBC, hepatic encephalopathy, deaths, variceal bleeding
ASCITES, PBC, CIRRHOSIS, HEPATIC ENCEPHALOPATHY, COMPLICATIONS
In entire cohort, adverse outcomes were recorded in 71 patients (12.5%), including 18 liver-related deaths, 3 liver transplantations, 50 complications of cirrhosis (30 ascites, 13 variceal bleeding, 5 with both ascites and variceal bleeding, one with hepatic encephalopathy and ascites, and one with hepatic encephalopathy, ascites, and variceal bleeding). Adverse outcome-free survival rates at 3, 5, and 10 years were 93%, 87%, and 75%, respectively (Fig. S1). Among patients with adverse outcomes, the mean time to the end-point was 3.5 years (median, 3.0 years). Importantly, 29 (41%) of them had an end-point within 2 years, and 56/71 (79%) patients within 5 years (Table Descriptive statistics of the number in 71 PBC patients with adverse outcomes over time*Median with interquartile range (IQR) were shown