Diagnostic performance of 3 scorings based on bpMRI
For the detection of csPCa, the sensitivity and specificity for Scoring 1 at cutoff ≥ 4 were 64.7% (95% CI 52.2%-75.9%) and 80.5% (95% CI 73.3%-86.6%); for Scoring 2 were 86.8% (95% CI 76.4%-93.8%) and 73.2% (95% CI 65.3%-80.1%) at cutoff ≥ 4; and for Scoring 3 were 61.8% (95% CI 49.2%-73.3%) and 80.5% (95% CI 73.3%-86.6%) at cutoff ≥ 8, respectively. The results showed that Scoring 2 had significantly higher sensitivity compared with Scoring 1 (P < 0.001) and Scoring 2 (P = 0.03) but with lower specificity (P < 0.01 for both). Figure 
A 63 years old man with elevated PSA of 11.1ng/ml and PSAD of 0.27ng/ml/ml. (