Acknowledgements
The study was supported and funded by Boehringer Ingelheim. Boehringer Ingelheim was involved in the study design, and collection and analysis of data, and was given the opportunity to review the manuscript for medical and scientific accuracy, as well as intellectual property considerations. The authors retained responsibility for the final decision to submit the paper for publication. Medical writing support was provided by Tom Priddle, DPhil, and Anna Wydra, MSc, of OPEN Health Communications (London, UK) and funded by Boehringer Ingelheim. PNN was supported by the National Institute of Health Research (NIHR) Birmingham Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. Agreements between Boehringer Ingelheim and the authors included the confidentiality of the study data. We thank all the patients and study investigators who participated in the clinical study described here.