Outcomes
fatigue, Fatigue
All outcome measures were assessed online at baseline before randomization in the non-inferiority study (T0), at the end of the 20-week treatment period prior to randomization for the current RCT (T20), 9 months and 1 year after the start of treatment (T39 and T52), respectively.Primary outcome was fatigue severity assessed with the CIS fatigue severity subscale. The CIS is a 20-item fatigue questionnaire, consisting of 4 subscales assessing fatigue severity (8 items), reduction in motivation, reduction in physical activity and concentration problems.Secondary outcome measures were other fatigue measures (Fatigue Severity Scale and PROMIS-Fatigue Short Form 8a