Supervised exercise programs
RPE, hypertrophy, overload
CUFF, HYPERTROPHY, ARTERIAL OCCLUSION
Patients in both the BFR and the control groups received supervised exercise sessions at the Exercise Research Laboratory (Centre of Sport and Exercise Science, Sheffield Hallam University), twice weekly for 8 weeks (total of 16 sessions), directed by an experienced exercise physiologist (TP). This frequency with progressive overload is sufficient to stimulate hypertrophy and strengthAll sessions began with a warm-up of 5 minutes of light cycling. Patients controlled the cadence and load which corresponded to a rating of perceived exertion (RPE) of 9–11 on the category-ratio (CR-20) scale.Patients in the BFR group completed the resistance exercises with the addition of a pneumatic cuff (13 cm wide, SC12L segmental pressure cuff, E20 Rapid Cuff Inflator, and AG101 Cuff Inflator Air Source; Hokanson, Indianapolis, IN, USA) placed around the proximal aspect of the legs (Placement of the pneumatic cuff on the legs.Arterial occlusion pressure was assessed at baseline following established procedures.Leg press and knee extension 1RM was predicted, using the repetitions to failure method as previously described,Predicted one-repetition maximum through the supervised exercise program illustrating progressive overload.Data are mean ± standard error of the mean.