Randomization
cancer
CANCER
After completion of informed consent, participants were randomized to either the intervention arm (Sanyrene) or the control intervention arm in a ratio of 1:1. The randomization procedures were carried out by sealed enveloping from the central office of the Clinical Trials Centre. Blocked randomization was performed using permuted block with a block size of n = 4. Patients were stratified by the presence of cancer site. Only the statistician and the study coordinator knew the block structure, and the statistician and the study coordinator had no clinical involvement during the trial.