Immunogenicity
®, LTB
Our study stands out as the largest thus far exploring the immunogenicity of ETVAX® amongst travellers. We examined LTB and LPS responses not only as indicators of immunogenicity but also as measures of vaccine intake pertinent to vaccine safety. Our results confirm previous findings showing that amongst the great majority of adults ETVAX® induces high IgA and IgG serum antibody responses against LTB.Responses against the O78 LPS antigen present in three of the four ETVAX® strains (fourth one a rough strain) were also frequent, with magnitudes comparable to those seen previously for adult Swedish volunteers as well as children in Bangladesh.