Introduction
synovitis, Rheumatoid arthritis, RA, disability
SYNOVITIS, RHEUMATOID ARTHRITIS
Rheumatoid arthritis (RA) is generally characterised by persistent synovitis, leading to joint destruction and disability, affecting approximately 1 in 200 adults worldwide.Bruton’s tyrosine kinase (BTK) is a candidate among the potential therapeutic targets for RA. BTK belongs to the Tec family and is expressed in B cells, monocytes/macrophages, mast cells, platelets and osteoclasts.