Background
sleep disturbance, trauma
THYROID NODULES
In recent years, the incidence of thyroid nodules has increased substantially, with an incidence of about 4% in adults [Lidocaine is an amide-based local anesthetic commonly used for local anesthesia, which could also act on the immune system, reducing the production and release of pro-inflammatory cytokines. Prior studies have found that lidocaine can decrease the serum levels of cytokines such as IL-1, IL-6, and TNF in a dose-dependent manner [Indeed, there is now evidence that the inflammatory reaction caused by surgical trauma is an important factor for postoperative sleep disturbance [Therefore, our study aimed at evaluating the association between intraoperative lidocaine infusion and the sleep quality of patients following thyroid surgery. We hypothesized that intraoperative lidocaine infusion could improve the quality of sleep and postoperative recovery for patients undergoing thyroid surgery.