Blood inflammatory profile
SENSITIVITY
Cytokine levels from unstimulated and stimulated blood samples were quantified using the V-PLEX Proinflammatory Panel 1 (human) Kit (MSD, K15049D). Cytokine quantification was done according to the manufacturer’s guidelines with one modification, where 100 μl sample was added directly onto the plate without dilution. C-reactive protein levels were quantified using the kit following the manufacturers guidelines (MSD, K151STD) using a 1000-fold dilution. Sensitivity of each assay is shown in Supplementary Table 