Author contributions
Conception/, TB
GP was involved in Data acquisition, Data analysis and Interpretation, Manuscript drafting. NNR contributed to Study Conception/ Design, Protocol publication, Data acquisition and interpretation. TB was involved in Study Design, Statistical analysis, Study steering committee. AS contributed to Data interpretation, Manuscript revision. FS, SU, JH, MBA, MS were involved in Data acquisition, Manuscript revision. PK contributed to Study Conception/ Design, Protocol publication, Data interpretation, Manuscript revision. RK was involved in Data interpretation, Manuscript drafting and revision. All authors have read and approved the final version of the manuscript and have agreed both to be personally accountable for the author's own contributions and to ensure that questions related to the accuracy or integrity of any part of the work, even ones in which the author was not personally involved, are appropriately investigated, resolved, and the resolution documented in the literature.