Study design
COMPLICATIONS
This randomized controlled prospective clinical study (simple randomization) was approved by the Institutional Ethics and Research Committee of Faculty of Medicine, Assiut University, Assiut, Egypt, with clinical trial registration number (Clinical Trials.gov Identifier: NCT03158168). A written informed consent was obtained from each patient or their guardians in case of children, after informing him/her about the technical and scientific basis of the research, the steps of the procedure, and the expected effects or possible complications.