Lipid parameters, body weight, and HOMA-IR
Mean LDL cholesterol increased (Figure Change in lipid parameters and body weight up to week 48. (A) Geometric mean percentage change (95% CI) in LDL cholesterol; (B) geometric mean percentage change (95% CI) in HDL cholesterol; and (C) mean change from baseline (95% CI) in body weight up to week 48 in all groups. Abbreviations: CVC, cenicriviroc; TXRA reduction in body weight from baseline was evident with TXR-containing groups by week 4. By week 24, the following mean changes from baseline were reported: TXRMedian HOMA-IR scores at baseline ranged between 4.60 and 6.63 across treatment groups, with the highest baseline score in the TXR