3. Results
HD, infections, infection, hypertension, diabetes
INFECTIONS, COVID-19 INFECTION, INFECTION, HYPERTENSION, DIABETES
The current study included 73 HD patients with a median age of 48 years and a majority (63%) of males. More than half of the patients had hypertension (60.3%), and 16.4% had diabetes. The study groups’ sociodemographic, clinical, and therapeutic characteristics are displayed in In terms of previous COVID-19 infections, 26% of patients had a history of infection. All the patients received the vaccine, and more than three-quarters received the SINOVAC vaccine. In terms of past COVID-19 infection and vaccination, there was no significant difference between the two trial groups, with a median interval of 145 days between the administration of the vaccine and cilgavimab–tixagevimab (Based on the non-Gaussian distribution of the NAB titer values, the values were categorized into three categories according to the first and third quartiles (200 and 800 AU/mL, respectively). The baseline NAB scores of individuals who did not receive Evusheld were significantly higher than those who did receive Evusheld (median score 3 vs. 2). Those who received Evusheld had higher NAB scores at one and six months compared to those who did not (median scores of 3 versus 2, and 3 versus 1.5, respectively) (Approximately one-fifth of both groups were diagnosed with COVID-19 throughout the six-month trial period, but the severity was greater in the control groups. Three of the six patients in the control group with a confirmed COVID-19 infection required ICU care, while the other three patients died from COVID-19 infection. Comparatively, of the 10 patients in the intervention group who contracted an infection, 4 had asymptomatic infections and 6 required hospitalizations, but neither ICU admission nor mortality occurred (The NAB scores for individual patients at various time periods are depicted in Regarding the short-term safety endpoint, only seven patients reported mild, well-tolerated side effects, none of which needed hospitalization (