2.6. Statistical analysis
The sample size for this study was based on clinical, rather than statistical rationale, and was considered adequate to address the study objective, which was to observe the treatment patterns and effects of avatrombopag in real-world practice. This objective was neither related to the testing of a specific hypothesis, nor to the precision of a particular estimate. The analysis population and the safety population analyzed were defined as all enrolled patients. The analysis of effectiveness endpoints was descriptive and based on data entered in the electronic case report form for enrolled patients. A 95% exact confidence interval (CI) (using the Clopper–Pearson method) was performed for the proportion of patients who received a platelet transfusion after the baseline visit and up to 7 calendar days following procedure day.