Results
ADVERSE EVENTS
Five patients, all from the intervention group, withdrew their consent to the study post randomization so that 43 patients completed the study: 19 in the intervention group and 24 in the control group. None of the patients consuming the supplement reported adverse events.The demographic and baseline characteristics of the two groups of patients are reported in Table Demographic and baseline characteristics of patientsContinuous data are presented as median (IQR) and analyzed by Wilcoxon rank sum test (W). Categorical data (smoking) are summarized by absolute frequencies and analyzed by chi-square tests (The stimulation and clinical outcomes are summarized in Table Stimulation and clinical outcomesContinuous data are presented as median (IQR) and analyzed by Wilcoxon rank sum test (W). Categorical data (pregnancy rates) are summarized by absolute frequencies and analyzed by chi-square tests with Yates’ correction (A positive beta-hCG at 7 days after embryo transfer was recorded in 12 out of 24 patients (50%) in the control group compared to 15 out of 19 patients (79%; The follicular concentration of Hcy showed a negative correlation with the clinical pregnancies (