Study design
alcoholism, psychosis, dermatologic disorders, allergies, infirmity disability, drug abuse
DISEASES, DERMATOLOGIC DISORDERS, ALLERGIES
A total of 130 female participants were enrolled in this study based on the inclusion and exclusion criteria displayed in Table Inclusion and exclusion criteria for enrollment of the study participants.Healthy females between 39 to 65 years of age at the time of enrollment.Able to understand and willing to complete a brief personal history, review and sign an informed consent document, and follow all study instructions.Lines/wrinkles in the periorbital area with a score greater than 2 cm and less than 8 cm on a standard 10 cm visual analog scale (VAS).Willing to come to the observation site without makeup.Willing to continue use of all regular brands of color cosmetics provided they do not make any moisturizing or anti‐aging claims.Willing to refrain from using new facial products other than the assigned test materials.Pregnant, breast‐feeding, or planning a pregnancy during the course of the study.Initiated the use of topical or oral prescription steroids and/or anti‐inflammatory medications within 30 days of study enrollment.Participating in any other clinical studies.Known allergies to personal care product(s) (self‐reported).History of sensitivity to skin treatment products.Any dermatologic disorders that may interfere with evaluation of test product performance.Any condition(s) apparent at entry or recognized after entry that are likely to invalidate a subject's consent to participate in this study and/or limit the ability of a subject to regularly attend all study visits or to comply with all other protocol requirements such as: diseases, injuries, alcoholism, drug abuse, psychosis, antagonistic personality, poor motivation, infirmity disability, other problems that may be emotional, intellectual, psychological or social.An employee of the testing facility or other testing firms/laboratories, cosmetic or raw goods manufacturers or suppliers.Visits to the testing facility occurred at week 0 (baseline), 2, 4, 8, and 12 for all participants, while a subgroup of participants were evaluated through to week 24. Participants were instructed to wash their face at least 1 to 2 h prior to each visit. Upon arrival, participants remained at room temperature for at least 15 min to allow the skin to equilibrate to ambient indoor conditions prior to evaluation.Self‐assessment questionnaire.