Montage-specific differences
depression, depressed
In this study, serial HD tDCS treatment induced significant neurostructural changes in depressed participants. No significant changes were observed with treatments administered using the conventional tDCS montage. This pattern of montage-specific changes was also observed in the follow-up analyses investigating post-treatment structural changes within each individual treatment group. Although not compared directly to sham, results suggest that HD-tDCS induces changes in the cortico-thalamic-striatal-limbic circuitry widely implicated in depression treatment studiesIn contrast to the montage-specific structural changes at the left DLPFC, comparable functional changes were induced by conventional and HD tDCS in the same region in the same cohort (demonstrated using ASL-MRI cerebral blood flow data, and reported in