3.5. Metabolic Risk Factors
weight loss, TG
Although there were significant improvements in glycemic control in both groups, dulaglutide + CRD provided additional benefits with regard to HbA1c and PPG levels as compared with CRD after equivalent weight loss. The groups both showed similar decreases in SBP, DBP, FINS, HOMA-IR, ALT, AST, TC, TG, and LDL-c values. The dulaglutide + CRD group appeared to have significant reductions in HDL-c levels, whereas the CRD group appeared to have significant reductions in SUA levels; however, there were no differences in the changes in HDL-c and SUA levels between the groups. With regard to liver fat content, a significant decrease in CAP was observed in the CRD group, whereas a significant decrease was observed in LSM in the dulaglutide + CRD group; yet, there were no significant differences between the groups in the changes in these parameters (