Study design
The study was designed as a randomized controlled clinical study with a parallel group design and a 12-month follow-up. The proposed null hypothesis was that there would not be differences in terms of MBL changes or soft tissue dimensions changes between two implants with different neck configurations 1 year after loading. The clinical study protocol was approved by the Ethics Committee of the Hospital Clinic San Carlos in Madrid (C.P.-C.I. 14/532-P) and followed the ethical principles founded in the Declaration of Helsinki. The protocol was registered in ClinicalTrials.gov (identifier NCT05051839). All patients gave their written informed consent and accepted to take part of the clinical trial.