Competing interests
AFX, ImmunoBrain, dementia
C.J.M. reports advisory board membership for Roche, Lilly, Biogen and Ionis; research grants from Biogen; seminar chair for Biogen; chair of data safety monitoring board for AD trial led by Imperial College; supported by the NIHR Biomedical Research Centre dementia subtheme at UCLH. M.J. reports advisory board membership for Biogen Sweden AB and BioArctic AB. S.D. reports salary support from the Fonds de recherche du Québec – Santé; consultancies from Biogen, Wave Life Sciences, AZTherapies and Janssen Pharmaceuticals; advisory board membership and/or speaker fees from Eisai, Biogen, Sunovion, Innodem Neurosciences, HealthTech Connex and QurAlis; cofounder of AFX Medical Inc. E.G.B.V. reports consultancies from New Amsterdam Pharma, Treeway, ReMynd, Vivoryon, Biogen, Vigil Neuroscience, ImmunoBrain Checkpoint and Brainstorm Therapeutics. PI of studies with AC immune, CogRX therapeutics, New Amsterdam Pharma, Janssen, UCB, Roche, GreenValley, Vivoryon, ImmunoBrain, Alector and Alzheon and sub-I from DIAN-TU, Alzheon, Eli Lilly, Cortexyme, Biogen en Fuij Film Toyama. L.M., K.M.M., C.Y., D.L., D.A.N., R.C., C.F.B., C.J. and R.M.L. are employees of, and hold stock in, Ionis. D.L.G., E.H. and E.R. are employees of, and hold stock in, Biogen. The remaining authors declare no competing interests.