Randomization and blinding
Participants who were determined to be eligible based on the inclusion and exclusion criteria and signed the Informed consent form for this clinical study were assigned to two groups at a ratio of 1:1 using a randomization table. The randomization table was created in advance by a statistician using R studio 1.1.463 (© 2009–2018 RStudio, Inc., Boston, Massachusetts, United States). The random sequence was generated by block randomization, and the size of one block was randomly set between 2, 4 and 6.The randomization results were sealed in an opaque envelope and delivered to each institution for storage under a double lock. Randomization and assignment of registration numbers for eligible participants was done by opening sealed envelopes. A random number assigned to each participant was recorded on an electronic chart. Due to the nature of our intervention, only evaluators were blinded to group assignments. The evaluator performed outcome evaluation in a separate space before intervention.