Modest changes to the fecal microbiota in response to 14-strain probiotic intake
First, the global microbiome composition was investigated. The relative abundance of fecal bacteria in the healthy adult population at baseline is presented at the genus and species level in To elucidate the impact of specific covariates in the microbiome, we first tested the association of the microbial composition with the covariates of interest (sex, age, participant, and time) by PERMANOVA. PERMANOVA demonstrated a significant impact of sex, age, and individual participant on fecal bacteria metataxonomy, with individual participant having the highest impact (84%) (The effects of multi-strain probiotic intervention on abundance distribution of family Overall the 14-strain interventional product did not elicit significant microbiota compositional changes, however in a simplified model that included only time and participant variables, there was a significant reduction in abundance of 