Patient characteristics
multiple myeloma
PLASMA CELL LEUKEMIA, DISEASE, MULTIPLE MYELOMA, RECRUITMENT
In total, seven patients were enrolled in this study and all gave informed consent. Due to rising number of competing trials and increasing number of successfully proven new treatment alternatives during the time of study initiation, enrollment had to be prematurely stopped after two dose levels due to slow recruitment. One patient in the second dose level did not reach the week 8 assessment due to progressive disease with development of a plasma cell leukemia, leading to the recruitment of an additional patient. All patients had progressive multiple myeloma according to IMWG criteria, but no immediate clinical need of a line of treatment. Of the 7 patients, 4 were male and 3 were female. At baseline, the median age was 81 (range 52–87 years) and the mean weight was 70 kg (range 57–91 kg). Further details are given in Table Characteristics of patients enrolled in the study