Ethics
The trial received ethical approval from the Faculty of Medicine, Pharmacy and Odonto-Stomatology Ethics Committee at the Université des Sciences, des Techniques et des Technologies of Bamako (Ref: 2016/03/CE/FMPOS). Secondary analysis of trial data was approved by the Observational/Interventions Research Ethics Committee at the London School of Hygiene & Tropical Medicine (Ref: 13832) and exempted by the University of California, San Francisco (Ref: 154824)