Safety evaluation
Clinical laboratory measurements were taken before and after the intervention period to assess the safety of the composition of methionine, threonine, and iron. The following physical parameters were measured: height, body weight, body mass index (BMI), body fat mass, blood pressure, and pulse rate. In addition, the following blood parameters were measured: white blood cell count, red blood cell count, hemoglobin, hematocrit, platelet count, total protein, albumin, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, total bilirubin, alkaline phosphatase, γ-glutamyl transpeptidase, urea nitrogen, creatinine, uric acid, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride, fasting plasma glucose concentration, glycated hemoglobin, sodium, potassium, chloride, iron, zinc, and magnesium.