Trial design and volunteer recruitment
allergic, metabolic abnormalities
This was a clinical trial conducted between January 2020 to March 2020 at the Department of Obstetrics and Gynecology of Kunming Tongren Hospital. Patients with BV were selected for a one-week intervention of a postbiotic gel to measure changes in the properties of vaginal discharge and vaginal microbiota before (day 0) and after (day 7) intervention. All (n = 50) patients diagnosed with BV at this hospital were considered for participation in the study and were screened by hospital professionals for eligibility. The inclusion criteria were: (1) women clinically diagnosed with diagnostic criteria for BV, aged 18-55 years; (2) body mass index between 19-24; (3) no history of heart, liver, lung, kidney, digestive tract, nervous system, and metabolic abnormalities; (4) not taken other vaginal preparation drugs 30 days before this trial; (5) voluntarily signed the informed consent. Subjects that were allergic to the postbiotics gel were excluded from this study (Trial design and enrollment information.