Secondary objectives and outcomes
CKD, anxiety, fatigue, inflammation, Depression, Fatigue
BLOOD, SECONDARY, KIDNEY, INFLAMMATION
The secondary objectives were to (i) establish whether Kidney BEAM could improve mental and physical wellbeing, physical function, fatigue and patient activation (a measure of an individual’s understanding, competence, and willingness to participate in care decisions and processes). (ii) Explore the perceptions and experiences of people who have used Kidney BEAM in the intervention group. Specifically, we proposed to examine whether Kidney BEAM delivered to adults with established CKD leads to improvements in the following outcomes:
HRQoL – Physical- and kidney-specific HRQoL, as measured by the physical component and kidney-specific summary scores of the KDQoL SF1.3 questionnaire.Healthcare utilisation - Quality Adjusted Life Year (QALY) profiles for the cost-effectiveness analysis, generated using the EQ-5D-5L [Fatigue - The Chalder Fatigue Questionnaire at 12 weeks [Life participation - The Work and Social Adjustment Scale (WSAS) [Patient activation- The PAM-13 [Self-reported physical activity - The Global Physical Activity Questionnaire (GPAQ) [Depression and anxiety - The Patient-Health Questionnaire-4 (PHQ-4) [Field test of physical function - Sit-to-Stand in 60 seconds (STS60) [Biochemical measures - Blood markers of inflammation and immunity (C-Reactive Protein, Interleukin 6, haemoglobin), kidney function (creatinine, estimated glomerular filtration rate,) and HbA1c.