Discussion
cerebrovascular disease, brain injury
OXIDATIVE STRESS, CEREBROVASCULAR DISEASE
IA is a cerebrovascular disease with high risk, high disability rate and high mortality [As a noninvasive and economical treatment, TEAS meets not only the requirements of the enhanced recovery after surgery (ERAS) concept but also the development of comfort medical care. According to the meridian theory of traditional Chinese medicine, Hegu (LI4), Neiguan (PC6) and Zusanli (ST36) are Yu acupoints and are the main acupoints for analgesia. In studies on the analgesic effects or mechanism of TEAS, many scholars often use these three acupoints compatibly [Inhaled anesthetics are effective vasodilators that can be used to maintain the stability of perioperative circulation, but they carry the risk of causing increased intracranial pressure during neurosurgery [OS is the basis of cerebrovascular disease development [NSE is a specific acid protease of neurons and neuroendocrine cells. S100β is a specific biological protein in the central nervous system, approximately 96% of which exists in the brain and is mainly produced by astrocytes. Under physiological conditions, the concentrations of NSE and S100β in serum are extremely low. After central nervous system injury, the integrity of nerve cells is destroyed, and NSE and S100β are released from cells into the blood, resulting in high expression levels of NSE and S100β in peripheral blood [This study has certain limitations. As this was a single-center study, the sample size was small, and further verification of the accuracy of the experimental results will increase the sample size. In addition, in order to objectively reflect the effects of TEAS on analgesic effect, oxidative stress injury and brain injury, only specific factors were selected as observation indicators in this study. More indexes, such as Methionine enkephalin, ROS/RNS, Neurofilament (NF), etc., were not used. Second, since the patients in this study were transferred to the neurosurgical intensive care unit for further treatment and monitoring after surgery, the follow-up of the patients in this study was only conducted 24 h after surgery, and the postoperative recovery of the patients was not followed up for a long time.