Progesterone regulates 
toxicity, PR-positive, PR-negative breast cancer, breast cancer
PR-NEGATIVE BREAST CANCER, BREAST CANCER
Preoperative hormonal treatments, as opposed to neoadjuvant chemotherapy, are simpler to administer, easier to monitor, less expensive, and cause less toxicity [In a separate study, we conducted functional analysis of the components found to be significantly altered after performing an integrated genomic profiling of a panel of PR-positive and PR-negative breast cancer cell lines treated with progesterone to investigate the molecular action of progesterone in breast cancer cells [