Primary outcomes
buphthalmos, obstruction of aqueous flow, myopia, glaucoma, corneal diameter, glaucoma-related AEs, Glaucoma
OCULAR HYPERTENSION, IOL, OCULAR HYPERTENSION, MYOPIA, GLAUCOMA, CORNEAL EDEMA, GLAUCOMA, INTRAOCULAR PRESSURE
The primary outcomes include IOL decentration and the incidence of glaucoma-related AEs by 1 year postoperatively.Glaucoma-related AEs are defined using the Infant Aphakia Treatment Study: “comprising ocular hypertension, pupil block, and glaucoma” [Ocular hypertension is defined as intraocular pressure (IOP) ≥ 21 mm Hg.Transient ocular hypertension is defined as elevated IOP which is resolved with cessation of topical steroids. Cases which do not resolve are classified as persistent ocular hypertension.Pupil block is defined as ocular hypertension in the context of a history of obstruction of aqueous flow through the pupil.Glaucoma is defined using the 2001 British Infantile and Childhood Glaucoma (“BIG eye”) study group taxonomy: “the presence of a combination (more than one) of clinical signs consistent with high intraocular pressure (≥ 21 mmHg), such as high pressure, optic disc cupping ≥ 0.3 or disc asymmetry ≥ 0.2, progressive disc cupping, buphthalmos, enlarged corneal diameter, corneal edema, Descemet’s membrane splits/Haab’s striae, visual field defects, or progressive myopia.IOL decentration will be measured using anterior segment optical coherence tomography (AS-OCT, CASIA2, Tomey Corporation, Japan) or Scheimpflug tomography (Pentacam HR 70900, Oculus GMbH, Germany) as previously described [