Statistical parameters of top 10 pharmacophore hypotheses generated for PPARδ using HypoGen algorithm.
BEST
Feature mapping was applied on the most active and least active compound of the training set for PPARδ selected pharmacophore which mapped with all features showed the fit score of 4.9 and 4.5 respectively ((A) Best pharmacophore for PPARδ (hypo3) with distance labeled chemical features. (B) The most active compound of the training set of PPARδ mapped on the pharmacophore model. (C) The least active compound of the training set of PPARδ mapped on the pharmacophore model.