Risk of recurring hematotoxicity
HAE
EVENTS
Among patients experiencing HAE, the median number of events was 1 (range, 1–4), with no difference between treatment arms (TMZ: 1 [range 1–4], CCNU/TMZ: 1 [range 1–4], p = 0.40). The risk of repeat HAEs during later courses among patients receiving at least one further course of chemotherapy after first HAE was 42.9% (15 of 35), numerically larger with CCNU/TMZ (47.6%, 10 of 21) compared to TMZ (35.7%, 5 of 14, p = 0.73).