Patient Population Selection and Definitions
death
KIDNEY
We retrospectively analyzed all patients between January 2013 and September 2018, who underwent IADS-based HLA desensitization protocol for deceased donor KT. Patients deemed eligible for the procedure had to fulfill the following criteria: 1) an incompatible graft ratio >85% calculated for a given individual on the basis of his anti-HLA antibodies profile and the HLA pattern stemming from nationwide kidney procurement performed over the last 5 years, 2) a favorable anti-HLA antibody dilution test performed using the LuminexFor each patient receiving the desensitization protocol, two control patients were selected from the same KT center. Controls were matched for age, degree of sensitization, had been waitlisted for a KT in the same year as the study patient, were of the same ABO blood group, and needed to have not died or be transplanted before the study patient had started the IADS protocol. Follow-up data for controls included KT status and date of KT and/or date of death.Kidney biopsies were scored according to the 2017 Banff classification.