2.4. Study Design and Protocol 
GI DISORDERS
During the screening visit, the study protocol was explained; the informed consent form was signed; and in- and exclusion criteria were checked. Weight, height, waist–hip ratio and body composition were measured. The latter was determined using a Bodystat1500 (Bodystat Ltd., Douglas, Isle of Man). Subjects tasted the chocolate milkshake for “liking” and were only included when they rated a score of 60 or higher on a 100 mm VAS to ensure the rewarding nature of the milkshake. An electrocardiography (ECG) confirmed the absence of a prolonged QT interval. Volunteers filled in the online screening questionnaires, including the Dutch version of the Rome IV criteria questionnaire to confirm the absence of functional GI disorders. This study was a placebo-controlled, double-blind, randomized, two-visit crossover study (