References
cutaneous allodynia, Anxiety, allodynia, pain, migraine disability, headache, migraine, Depression
MIGRAINE, SECONDARY
Mean change from baseline in frequency of headache days in the placebo and BoNT-A group treated with SjBoT paradigm.Mean change from baseline in frequency of headache days in the occipital and trigeminal group after BoNT-A treatment with SjBoT paradigm.Subcutaneous injections of BoNT-A-targeted (SjBoT) study design.The “follow the origin of maximum pain” approach: based on the skin area of origin of maximum pain, patients were assigned to trigeminal or occipital treatment with BoNT-A (central panel). SjBoT injection paradigm: the skin sites of the trigeminal region injected with BoNT-A (Demographics and characteristics of the 139 patients with chronic migraine.Abbreviations: F, female; M, male; ASC-12, validated 12-item allodynia symptom checklists; CA, cutaneous allodynia; AS, visual analog scale; MIDAS, migraine disability assessment; BDI II, Beck Depression Inventory II; HARS, Hamilton Anxiety Rating Scale.Effects of BoNT-A or placebo treatment with the SjBoT paradigm on secondary endpoints in chronic migraine patients.SjBoT denotes subcutaneous injections of BoNT-A targeted; 