Introduction
PRIMARY ALDOSTERONISM, SECONDARY HYPERTENSION
Primary aldosteronism (PA) is a common form of secondary hypertension.Corticotropin (ACTH) is used during AVS in some centers due to reported benefit of increasing the rates of successful adrenal vein cannulation.To our knowledge, the outcomes of treatment following AVS with or without ACTH stimulation have not been evaluated in a prospective study. Therefore, we conducted a randomized clinical trial (RCT) to evaluate whether the treatment decision (surgical or medical treatment) based on different AVS procedures (with or without ACTH stimulation) would lead to different outcomes in patients with PA. The results of this study may provide insights into the value of ACTH stimulation in AVS for PA subtyping.