Patients
NF1-related, NF1
Adult patients were eligible to enrol if they were aged between 18 and 70 years with confirmed NF1-related PN with a requirement of systematic therapy per Investigator’s judgment. The diagnosis of NF1 was made if at least one of the two diagnosis criteria was met: (1) positivity for NF1 germline mutation per Clinical Laboratory Improvement Amendments-certified laboratory (or equivalent) testing; (2) the presence of at least 2 of 7 manifestations or features according to the National Institutes of Health consensus criteria [