Patients and randomization
knee infection, TKA, flexion-contracture, knee osteoarthritis
WEST, COAGULOPATHY, KNEE OSTEOARTHRITIS
This study has been reported in line with Consolidated Standards of Reporting Trials (CONSORT 2010) Guidelines. This single-center, double-blind, randomized controlled trial was approved by the Biomedical Ethics Committee of Sichuan University West China Hospital (date February 8, 2022/no. 2021–1699). All patients who were candidates for cemented TKA at our hospital from February 2022 to June 2022 were considered for inclusion. Patients were included if they underwent TKA for knee osteoarthritis in our hospital and showed a flexion-contracture deformity  of < 20°, varus or valgus deformity of < 20° [Patients were excluded if they had a history of knee infection, had a level of hemoglobin of < 100 g/L or coagulopathy, were using anticoagulants or antiplatelet drugs, had a body mass index (BMI) of > 40 kg/mPrior to TKA, patients were randomly assigned 1:1 to a group that received a tourniquet during TKA or to a group that did not. Random numbers were generated using a computer algorithm and sealed in opaque envelopes. Each patient was asked to select an envelope, inside which their group allocation was indicated. Observers who collected data after surgery were not involved in the surgery and were unaware of the group allocation.