PGIC-CML: patients’ impression of change in CML symptoms
CML
CHRONIC MYELOID LEUKEMIA, CML
The PGIC-CML is a single-item scale that asks: “Since the start of the treatment you’ve received in this study, your Chronic Myeloid Leukemia (CML) symptoms are…” with seven response options: (1) very much improved, (2) much improved, (3) minimally improved, (4) no change, (5) minimally worse, (6) much worse, and (7) very much worse. For the analysis reported herein, responses were grouped into “improved” (1–3), “no change” (4) and “worsened” (5–7). The PGIC is a commonly used measure of improvement or deterioration over time relative to treatment.