Author contributions
Z.X., W.Z., H.Y., Y.-T.Z, J.Z. and J.S. conceptualized and designed the study. Z.X., C.P., and W.Z. performed the in silico study. D.S., X.L., J.J., M.Z., N.W., M.Z. and H.Y., performed the in vitro study. J.-B.H., X.J., T.-Z.S., X.-L.F., R.-R.T., C.W., Z.X., Z.W. and J.S. performed the i