SIAscope
The skin content of melanin and collagen was quantified via spectrophotometric intracutaneous analysis using the Cosmetrics SIAscope (Astron Clinica Ltd.; Cambridgeshire, United Kingdom), an instrument that consists of a probe connected to a laptop computer. The probe is hand‐held and is first placed in direct contact with the skin surface on one side of the face. The light‐emitting diodes inside of the probe then shine a spectrum of visible and infrared light onto the skin at discreet wavelengths of 400 to 1000 nm.