Introduction
LIVER FAILURE, LIVER, CDA
Liver transplant is a life-saving therapy for liver failure, but its success is limited by a marked shortage of organs and high mortality among individuals on the waiting list.Livers from extended-criteria donors are more susceptible to ischemia-reperfusion injury (IRI),Over the past decades, evidence from small- and large-animal models has indicated that pharmacological targeting of IRI pathways is a promising strategy to attenuate IRI,Although advocated over the past decade, to our knowledge, a CDA strategy has so far not been tested in the clinic.