Study design
upper ureteric stones, kidney stones, hepatitis
KIDNEY STONE, HEPATITIS, GROUP B, UTI
This prospective randomized study was conducted at Benha university hospital, urology department in the period from February 2022 to February 2023. All patients applied written informed consent and our local ethical committee approval was obtained (MD.9.2.2022). The inclusion criteria involved patients aged ≥ 18 years with single large impacted upper ureteric stones (located just below PUJ and above the lower limit of the fourth lumber vertebra) ≥ 1.5 cm in maximum dimension. Patients with kidney stones, obstruction distal to the stone, active UTI and pregnant females were excluded.Patients were randomly divided into two groups using a closed-envelopes method.Group A: included 31 patients who treated by antegrade FURS procedure and holmium laser fragmentation.Group B: included 30 patients who treated by retrograde FURS procedure and holmium laser fragmentation.All patients subjected to complete history taking, physical examinations. Urine analysis, urine culture, serum creatinine, complete blood count, hepatitis marker and coagulation profile were assessed as preoperative laboratory investigations. Patients with positive urine culture received the specific antibiotic up to the urine culture registered negative. while patients with negative urine culture received a single dose of first generation cephalosporin for operation. Radiological investigations for all patients were done, including pelvic-abdominal ultrasonography (us), plain radiograph of the kidneys, ureters and bladder (KUB) and non-contrast CT to determine stone criteria.