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DISEASE, TYPE 2 DIABETES
The burden of type 2 diabetes is far reaching, with an estimated 415 million people affected worldwideIn the initial stages of the disease, most people with type 2 diabetes require a combination of lifestyle interventions and pharmacological therapy, benefiting from the availability of an increasing number of oral antihyperglycemic agentsClosed-loop insulin delivery offers a new, glucose-responsive method of glucose control and comprises a continuous glucose monitor, an insulin pump and a control algorithm that automatically modulates subcutaneous insulin deliveryFully closed-loop systems, which are more convenient and have no requirement for user input at meal times, have previously been shown to improve glucose control in people with type 2 diabetes in the inpatient setting