Discussion
forgetfulness, dementia
This study evaluated the effects of continuous egg yolk choline ingestion at 300 mg on cognitive function in middle-aged and older adults who were aware of healthy forgetfulness but not dementia or who had been indicated by others for forgetfulness. The results showed that there was a significant improvement in the choline group compared with the placebo group in verbal memory ability, a part of the cognitive function.In this test, plasma choline concentration was measured. Previous studies revealed that phosphatidylcholine ingestion increases plasma free choline and brain acetylcholine levels [The ingested egg yolk choline is well absorbed in the small intestine by a complex mechanism. PC is degraded to LPC by pancreatic phospholipase A2 in the small intestine [The processing speed score and SDC test used to calculate the rate of processing efficiency were significantly higher in the placebo group after 6 weeks, although these parameters have been reported to be a function related to cholinergic nerves [Soybean is also a well-known source of phospholipids, but egg yolk phospholipids have a high level of PC of approximately 80% compared with an approximately 30% in soybean [