3.3. Stratified macular pigment optical density analysis based on axial length
−0.09
MPOD outcomes were further stratified using different AL strategies (Table MPOD scores in the Lutein groups before and after Lutein administration using the PPS.Data are expressed as mean (standard deviation).AL = axial length, PPS = protocol per set.In the AL ≤ 28.25 mm subgroups, the average of AL at baseline was 27.50 ± 0.46 mm in the lutein group and 27.66 ± 0.59 mm in the control with no significant difference between the groups. After 3 months from baseline, the change in MPOD in the lutein and the control group was 0.06 ± 0.17 and −0.04 ± 0.20, respectively, with no significant difference between the groups. The rate of MPOD changes in the lutein and the control group was 0.09 ± 0.23% and −0.02 ± 0.30%, respectively with no significant difference between the groups. In contrast, after 6 months, the changes in MPOD from baseline in the lutein and control groups were 0.09 ± 0.10 and −0.09 ± 0.05, respectively, and the rate of MPOD changes from baseline in the lutein and control groups was 0.13 ± 0.15% and −0.12 ± 0.04%, respectively, with a significant difference in both the values and rate (