Paper context
disease reduction
Activating community health volunteers in Ghana to induce disease reduction in children did not meet the realistic cost-effectiveness thresholds in low- and middle-income countries. Although, there was a high probability that one dollar’s investment in activating community health volunteers in Ghana would yield more than 3 dollars return in cost-benefit analysis. This study provides valuable insights to specify the optimal scope of work for the dual cadres of community health workers in the resource-scarce setting.International Standard Randomized Controlled Trial Registry, ISRCTN49236178. 