Study design and settings
Cancer
CANCER
This randomized controlled trial was conducted at National Cancer Center Hospital (NCCH) in Tokyo, Japan. It was approved by the institutional review board for human clinical studies (no. 2017–504), and written informed consent was obtained from all patients. The study was carried out following the Declaration of Helsinki and registered in the University Hospital Medical Information Network (UMIN) Clinical Trial Registry (UMIN000034798) on December 12, 2018.