2.6. Statistical Analysis
constipation
The statistical analysis was performed with IBM SPSS statistics V.20 software. A double-blind clinical trial was performed using intention-to-treat analysis on all patients who underwent randomization (n = 50). The additional analysis included only those subjects who completed the study (n = 39). Analysis of anthropometric results revealed no statistically significant differences between these two groups, and the results for the intention-to-treat analysis are presented with Cochran and Wilcoxon comparative analysis for all nonparametric variables. The primary endpoints were changes in constipation, the total QOL, the HADS and its subscales, and the Bristol scale. Comparisons between the treatment and placebo groups were performed using Student’s 