Author contributions
XZ, LX, and LG designed the research. SF, JL, LH, XL, YL, and YZh carried out the clinical trial. XZ, LG, FQ, JL and SZ supported the clinical trial and organized data. FQ, CF, ZH, YZo and SZ analyzed the data. FQ, XZ, CF, and ZH draft the paper. LX, SF and LG provided critical revisions of the article. LG, YZh, and HZ were responsible for the probiotic product support. XZ and XL supervised the project. All authors contributed to the article and approved the submitted version.