Introduction
death
CONTRACTIONS
Induction of labor at or beyond 37 weeks of gestation is associated with a clear reduction in perinatal death compared to expectant management. It also reduces cesarean section rates without increasing operative vaginal deliveries and fewer Neonatal Intensive Care Unit (NICU) admissions [However, induction failure was reported as high as 23.7% in multiparas and 41.2% in nulliparas [These facts explain why every effort is made to shorten the induction to the delivery interval with the least maternal and neonatal morbidities. Induction of labor in circumstances where the cervix is unripe with a low Bishop score carries a higher chance of failure [Misoprostol, a synthetic PGE1, has uterotonic properties, by contracting smooth muscle fibers in the myometrium and cervical relaxation, facilitating cervical dilatation and effacement. Compared to other prostaglandins, misoprostol has several potential advantages. It is stable at room temperature, cheap, and can be given by several routes [Propranolol is a non-selective beta blocker that was studied to induce uterine contractions in several studies. This triggered a wide investigation of the presence of beta receptors in human myometrium and their role in myometrial contractility [