Population
MAY
This randomized double-blinded controlled clinical trial included 45 patients, each contributing with one periodontal intrabony defect. Patients were selected from the Medicine, Oral Diagnosis, & Periodontology Department of the Faculty of Dentistry, Minia University outpatient clinic from May 2020 to December 2021. The International Conference on Harmonization Good Clinical Practice Guideline, the Declaration of Helsinki, and the research ethics committee guidelines of the Faculty of Dentistry, Minia University were all followed during the study (No. 466 November 30, 2020). This study was registered in ClinicalTrials.gov U.S. National Library of Medicine under the number NCT05653245.