Outcomes
death, cerebral infarction, Stroke, intracranial hemorrhages
STROKE, SECONDARY, ADVERSE EVENT, INTRACRANIAL HEMORRHAGES, CEREBRAL INFARCTION
The primary outcome was measured via modified Rankin Score (mRS) (range 0–6; 6 indicates death) at 90 days post randomization. The mRS score was further categorized as an excellent functional outcome (mRS of 0–1), a favorable functional outcome (mRS of 0–2), and a moderate functional outcome (mRS of 0–3). Barthel index was also ascertained at 90 days. The clinical secondary outcomes were the improvement of National Institutes of Health Stroke Scale score (NIHSS) at 24 h and 5–7 days or discharge post-procedural 5–7 days after randomization. The procedural secondary outcomes included angiographic recanalization measured via the extended thrombolysis in cerebral infarction (eTICI) score (range 0–3), total attempts of thrombectomy, and outcome lesion volume on computed tomography (CT).Safety outcomes were death, asymptomatic intracranial hemorrhages and symptomatic intracranial hemorrhages according to the Heidelberg criteria [The outcomes of patients were independently analyzed. The functional outcome was evaluated by an independent outcome assessment committee and the adverse event was judged by the adverse event committee. Radiological outcomes were evaluated by an independent imaging core laboratory.