Follow-up
cancer, deaths
CANCER, EVENT
Participants were actively followed from the last event registered before December 2019 until December 31, 2021. In the FIT group, an interval colonoscopy was defined as any colonoscopy performed after a negative FIT result. In the colonoscopy group, interval colonoscopy referred to colonoscopies performed within 36 months after a baseline colonoscopy. Unplanned FIT was defined as any FIT performed because of abdominal symptoms in both study groups or when it was performed as a screening tool in the colonoscopy group. Screening tests, interval colonoscopies, unplanned FIT, post-polypectomy surveillance, interval CRC, and deaths were identified through cross-linkage of the study database and the regional intranet network, which provides access to the electronic medical records at each site. Interval cancer was defined as cancer occurring between 6 and 36 months after a negative colonoscopy screening [