Secondary outcomes
Hospital-acquired infection, HAI
ADVERSE DRUG REACTIONS

Each of the three components of the composite safety outcomeSuspected adverse drug reactions (ADR), categorised using the Liverpool Causality Assessment Tool [Hospital-acquired infection (HAI) up to 28 daysTotal duration of antibiotic use (IV and oral), derived from the starting and stopping times of antibiotic use (hours)Time to switch from broad to narrow spectrum antibiotics (hours)Time to discharge from hospital (hours)