Results From the Generalized and Linear Mixed Model Analyses and Effect Sizes
SE, assessor-rated NSSI, NSSI
REGRESSION, SECONDARY, ADVERSE EVENTS, POSITIVE
Abbreviations: BSL, Borderline Symptom List; CGAS, Children’s Global Assessment Scale; Of count and continuous outcomes evaluating treatment differences in change from pretreatment to 1-month posttreatment (primary end point) and 3-month posttreatment (secondary end point). Fixed-effects parameter estimates β (SE) represent the time × group interaction with all randomized individuals (166 total). Positive effect sizes IRR and Numbers of participants contributing with data.This outcome was analyzed using a zero-inflated negative binomial regression model.Effect size result is an IRR.This outcome was analyzed using a zero-inflated Poisson regression model.This outcome was analyzed using a linear mixed effects regression model assuming a normal distribution.Effect size result given as Compared with TAU only, adolescents in IERITA plus TAU had larger improvements in self-reported emotion dysregulation (DERS: Masked assessors were not more accurate than chance at guessing participants’ condition at 1-month posttreatment, although they were slightly more accurate than chance at 3-month posttreatment. The number of assessor-rated NSSI episodes at 1-month posttreatment (β [SE] = 0.29 [0.33], The mediation analysis indicated that, relative to TAU only, IERITA plus TAU led to greater decreases in emotion dysregulation, which, in turn, were associated with decreases in NSSI. The estimated indirect (mediated) effect (Five participants (6%) reported suicide attempts in the IERITA plus TAU condition during the study period, compared with 9 participants (11%) in the TAU only condition. Further information on adverse events is presented in the eResults in 