Author contributions
MP
MP: Conception and design of the MANCTRA project and the MANCTRA-1 study (including pre-planned post hoc analyses); Acted as study principal investigator and guarantor of the integrity and precision of the manuscript with the other co-authors, as well as informed of other authors’ roles in the work; Acquisition, analysis, and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. GP: Conception and design of the MANCTRA project and the MANCTRA-1 study; Acquisition, Analysis, and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. SS: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. FC: Conception and design of the MANCTRA project and the MANCTRA-1 study; Acquisition, Analysis, and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. DP: Conception and design of the MANCTRA project and the MANCTRA-1 study; Acted as statistical advisor and data management lead; analysed and interpreted data for the study; Drafted the study and revised it critically for important intellectual content; Final approval of the version to be published. SPBC: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. FV: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; drafting and revising it critically for important intellectual content; Final approval of the version to be published. AB: Conception and design of the MANCTRA project and the MANCTRA-1 study; Acquisition, Analysis, and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. BI: Conception and design of the MANCTRA project and the MANCTRA-1 study; Acquisition, Analysis, and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. FP: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. GP: Conception and design of the MANCTRA project and the MANCTRA-1 study; Acquisition, Analysis, and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. MO: Conception and design of the MANCTRA project and the MANCTRA-1 study; Acquisition, Analysis, and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. DD: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. BS: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; drafting and revising it critically for important intellectual content; Final approval of the version to be published. MS: Conception and design of the MANCTRA project and the MANCTRA-1 study; Acquisition, Analysis, and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. AL: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. KJ: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. FC: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; drafting and revising it critically for important intellectual content; Final approval of the version to be published. AG: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. MM: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. AP: Conception and design of the MANCTRA project and the MANCTRA-1 study; Analysis and interpretation of data for the study; Drafting the study and revising it critically for important intellectual content; Final approval of the version to be published. The MANCTRA-1 Collaborative Group: Conception and design of the MANCTRA project and the MANCTRA-1 study; Acquisition of data for the study; Revising it critically for important intellectual content; Final approval of the version to be published.