REGISTRATION:
ICH, Intracerebral Hemorrhage
INTRACEREBRAL HEMORRHAGE, DISEASE, INTRACEREBRAL HEMORRHAGE (ICH)
URL: Intracerebral hemorrhage (ICH) is a devastating disease with high mortality and morbidity.Currently, no evidence-based hemostatic treatment exists for NOAC-associated ICH.Tranexamic acid (TXA)—an antifibrinolytic drug—has been investigated in non–NOAC-associated ICH, most notably in the recent TICH-2 trial.Here, we report the results of TICH-NOAC (Treatment of Intracerebral Hemorrhage in Patients on Non–Vitamin K Antagonist Oral Anticoagulants With Tranexamic Acid), a randomized placebo-controlled trial investigating the effect of TXA on HE among patients with NOAC-associated ICH in addition to standard medical care.