Lead placements
Based on MRI analyses in stereotactic space, more anterior lead placements appeared to be favorable (A) Lead placement correlates, and B) single-unit recordings. A) MRI results suggest that more anterior lead placements were favorable. B) Single-unit recordings show two clusters of neurons (cluster-1 being faster and more regular versus cluster-2 being slower and less regular). Neurons resembling cluster-2 were more prominent in recording trajectories of patients with more anterior electrode placements (who had better therapeutic responses).