Study products
low abuse
Vuse Vibe and Vuse Ciro products are pre-filled, closed-tank vapor products (RJR Vapor Company, Winston-Salem, North Carolina) that were commercially available at the time the study was conducted. The Vuse Vibe power unit is powered by a ≥ 550 mAh rechargeable battery and is paired with a cartridge containing 1.9 mL of e-liquid with 3% nicotine content by weight (36 mg/mL) and a propylene glycol to glycerin ratio (PG/VG) of 20/80. The Vuse Ciro power unit has a ≥ 260 mAh battery and uses a cartridge containing 0.9 mL of e-liquid with 1.5% nicotine by weight (17.7 mg/mL) and a 29/71 PG/VG ratio. Both Vuse Vibe and Vuse Ciro were used with Original, tobacco-flavored e-liquids.Comparator products were participants’ UB cigarettes as a high abuse liability product and Nicorette® White Ice Mint nicotine polacrilex nicotine replacement therapy (NRT) gum containing 4 mg of nicotine (GlaxoSmithKline, USA) as a low abuse liability product.