Introduction
T2D, bleeding, periodontitis, inflammation, gingivitis, Diabetes
BLEEDING, PERIODONTITIS, INFLAMMATION, GINGIVITIS, DIABETES
Diet, genetic factors, and a healthy lifestyle, may explain why Okinawa islanders are renowned for their longevity [Recent data suggest that individuals with T2D consuming a diet based on the OBND concept may reduce body weight, improve blood lipids, and glucose levels [Many studies demonstrate that a diagnosis of gingivitis and/or periodontitis is common in individuals with T2D. According to the Swedish National Diabetes Care guidelines (2015) medical professionals should refer patients for dental treatment in cases of persistent gingivitis or periodontitis [The aim of the present study was to assess if (I) short-term tangible benefits with OBND in terms of medical and dental health outcomes over a short study period, and if (II) the study outcomes differed between individuals with T2D using OBND compared to a standard hospital care diet suitable for individuals with T2D (control group diet). Primary outcome measures were: changes in serum HbA1c levels, and the severity of gingival inflammation as assessed by evidence of bleeding on probing (BOP). Secondary outcomes were changes in serum levels of cytokines.