Use of the AMBITION Regimen in High-Income Settings
AIDS
INFECTIOUS DISEASES, AIDS
What about use of the AMBITION regimen in high-income settings? Are patients living with HIV in high-income countries now actually at risk of being “left behind,” with unnecessarily long and toxic 2-week courses of daily liposomal amphotericin or even amphotericin deoxycholate? The recommended first-line induction regimen in high-income settings is liposomal amphotericin at 3–4 mg/kg plus flucytosine 100 mg/kg/d for 14 days, a recommendation that is consistent with those from the Infectious Diseases Society of America, British HIV Association, and European AIDS Clinical Society [