Endoscopic screening
neoplasia, esophageal and gastric mucosae
NEOPLASIA, PREMALIGNANT LESION

Endoscopic screening was performed with high definition endoscopes by expert endoscopists (A.D.K., M.C.W.S., P.J.F.dJ, S.N., and W.dG.), who each had more than 5 years’ experience in the detection of neoplasia in the upper GI tract. All endoscopists participated in a dedicated upper GI screening program and had extensive experience in the detection of premalignant lesions in the upper GI tract. Endoscopic screening was performed with high definition white-light endoscopy (WLE), optical chromoendoscopy (narrow-band imaging [NBI]), and Lugol’s staining. First, the mucosae of the stomach, duodenum, and esophagus were carefully inspected with WLE. Second, the esophageal and gastric mucosae were inspected again with NBI. After switching back to WLE, 10–30 mL of Lugol’s staining (1.2 % iodine solution) was applied to the esophageal mucosa with a spray catheter or syringe. Visible lesions were classified according to the Paris and intrapapillary capillary loop classifications, and assessed for endoscopic resectability
