Cost-Effectiveness Analysis
SECONDARY
Effectiveness was measured in terms of the secondary outcomes. The incremental cost-effectiveness ratios (ICERs) were calculated using the following formula:The mean difference in health care resource use costs included the costs of implementing the intervention plus the indirect costs associated with health care use (eg, hospital admissions and ED presentations). The difference in effects was calculated as the change from baseline to 6 months and from baseline to 12 months for each secondary outcome per individual participant. The mean difference of these individual differences was then calculated using 2-tailed independent samples 