Background
anxiety, Low back pain, pain, muscle spasm, tiredness, depression, LBP
BENDING
Low back pain (LBP) is a common health problem throughout the world, with an estimated yearly global prevalence of 38% [Acute episodes of non-specific LBP can be triggered by physical (e.g., bending, twisting, lifting) and/or psychosocial (e.g., tiredness, stress, anxiety, depression) factors [Alleviating the intensity of pain and improving the mobility and physical function of patients are the main therapeutic goals of acute LBP management [The combined use of NSAIDs and skeletal muscle relaxants, both of which can be administered orally or intramuscularly (IM), can target simultaneously both of the components of the spasm-pain-spasm cycle, and thus, represents an advantageous therapeutic option in the treatment of acute LBP compared to either agent alone [Thiocolchicoside, a well-known competitive GABAClinical evidence has confirmed that the combination of thiocolchicoside and NSAIDs was more effective than NSAID alone in the symptomatic treatment of acute LBP for both pain relief and muscle spasm [