5. Study Limitations
ANS dysfunction, T2DM, hypertensive
OBESE
There are limitations that must be acknowledged. This study included a small sample of heterogeneous participants in T2DM with ANS dysfunction, with more than half who are also hypertensive and mild to moderately obese; thus, we are unable to control for these confounder variables or medications used. This population is a rather typical patient mix frequently seen in primary care offices. Despite the small sample size, we show a clinically significant effect of 7 days of JD on the various parameters of HRV (SDNN, SD