Ethics approval and consent to participate
The study was approved by the Ethics Committee of the First Affiliated Hospital of Guangxi Medical University [Ethics No. 2020 No. (028)] and registered in the Chinese Clinical Trial Registry on 3/11/2020 (Registration No.: ChiCTR2000039610). Before the study, the patients were informed orally and in writing of the relevant details and risks, and gave signed informed consent. We confirm that all methods were performed in accordance with the Declaration of Helsinki and relevant guidelines and regulations.