Strategies to improve adherence to interventions {11c}
Study treatment intake will be observed by study staff during the study visits in the morning and will be administered at home on the other days. Facility-based directly observed treatment or community-based directly observed treatment (i.e. a friend or relative of the participant will act as a treatment supervisor) will be in place in order to maximize adherence. Furthermore, treatment adherence will be assessed by pill counting at every visit.