Introduction
T-cell depletion
ADHESION
In recent decades, rabbit anti-thymocyte globulin (ATG) was the most commonly used induction agent for kidney transplantation worldwide. ATG was found to induce T-cell depletion and modulate cell surface molecules and adhesion molecules that regulate T-cell function and leukocyte-endothelial interaction, respectively [Several studies have reported the dose optimization of ATG as induction therapy in kidney transplantation [The aim of this study was to compare the efficacies of 4.5 mg/kg ATG and 6.0 mg/kg ATG in non-sensitized living-donor kidney recipients with early steroid withdrawal in an Asian population, and to investigate the immunologic profiles thereof during follow-up.