Study design
MAY
This randomized, controlled, double-blind, single-center trial was conducted between December 2020 and May 2022 at the Department of Orthopedics of Fujian Provincial Hospital, Fuzhou, China. This trial was conducted in accordance with the Declaration of Helsinki and approved and supervised by the Fujian Provincial Hospital Ethics Committee (K2020-09–075). The trial protocol was registered in the Chinese Clinical Trial Registry (ChiCTR2000040311). This study was conducted according to the Basic & Clinical Pharmacology & Toxicology policy for experimental and clinical studies [