Statistical Analysis
VBAI
EVENT
Analysis was performed on an intent-to-treat basis. The primary outcome of the time to optimal insulin dose was assessed using the log-rank test to compare time to event for the VBAI group vs standard of care. Standard methods for mean values and proportions were used to construct 95% CIs and to conduct tests. Specifically, the Welch 2-sample method was used to test for differences in insulin adherence, change in composite survey scores (baseline to 8 weeks), and change in 3-day mean FBG level (baseline to 8 weeks) between VBAI and standard of care groups. The 2-sample test for equality of proportions with the Yates continuity correction was used to assess differences in glycemic control.We reviewed participants’ medical records to supplement any missing data for our outcomes related to time to optimal insulin dose, mean glycemic control, and glycemic improvement. If FBG values were incomplete in the final 3 days of the trial, the last 3 available FBG values were used.Analyses were performed from January to February 2023 using R statistical software, version 4.2.1 (R Project for Statistical Computing). Statistical significance was defined as 2-sided 