Composition of the coordinating centre and trial steering committee {5d}
TSC
The TSC will be composed of at least 3 voting members, including a representative of the sponsor, the coordinator of the PanACEA consortium and an independent clinician.The role of the TSC is to provide overall supervision of the trial and ensure that the trial is conducted in accordance with Good Clinical Practice and Good Clinical Laboratory Practice principles. TSC meetings will be held on an ad hoc basis throughout the trial from first-participant-in to last-participant-out to evaluate participants’ safety. The TSC will formally report to the Sponsor. TSC specifics will be detailed and justified in the TSC charter.