Discussion
crowding of upper anterior teeth, bone injury, RAP, piezocision, orthodontic
BLIND
This is the first RCT assessing 3D piezocision-assisted orthodontic in correcting severe crowding of upper anterior teeth in adult patients who underwent extraction-based orthodontic treatment. It was found that 3D guided piezocision accelerated leveling and alignment by about 53%. This could be explained by the regional acceleratory phenomenon (RAP) following the intentional bone injury [In contrast, Uribe et al. found no significant difference between the control and the piezocision groups in terms of the alignment time [Other RCTs have accomplished regarding the efficacy of piezocision in accelerating orthodontic treatments in combination with Self-ligating brackets recently [Regarding the 3D surgical guide accuracy, the indications of computer-guided piezocision are limited by the maximum deviation detected, which is set as a safety distance of 1.5 mm among anatomical vital structure [Highly accurate recorded outcomes confirm that employing 3D techniques in orthodontic acceleration approaches is an essential aid, especially for flapless techniques since they were mentioned as blind procedures. No significant harms were observed during the entire duration of the study.