Intra-articular injection of IMRCs relieves pain and improves knee function
pain
OSTEOARTHRITIS
The pain intensity was assessed on a 10-point Visual Analogue Score (VAS). In a total of 18 cases, the VAS (described as mean ± SEM below) decreased from 3.50 ± 0.40 before treatment to 1.69 ± 0.33 at week 48 after IMRCs injection, and the VAS pain intensity in patients was significantly decreased compared to the baseline (week 1, The knee function was assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, the Lysholm knee score, and the American Knee Society (AKS) knee score. The WOMAC score in 18 cases decreased from 14.94 ± 1.83 baseline to 10.81 ± 5.29 at week 48, a tendency that indicated improved outcome of knee function (Fig. 