Acknowledgements
This study was funded by Shanghai Henlius Biotech, Inc. We thank the patients, their families and the study personnel involved in this trial. We thank the clinical study team (clinical operations, Lu Luo, Guiyu Yang and Haoyu Yu; statistics, Xiao Qi and Jianchen Cheng) and Wenjie Zhang from Shanghai Henlius Biotech, Inc, for their support in study execution, study design, data acquisition, statistical analyses and manuscript revisions. We thank Shiqi Zhong and Chen Hu from Shanghai Henlius Biotech, Inc. for their assistance in writing this manuscript. The study was designed by the lead principal investigator (J.H.) and Shanghai Henlius Biotech, Inc. Shanghai Henlius Biotech, Inc. contributed to data collection and data interpretation in collaboration with all investigators, funded data analyses and participated in manuscript preparation with all authors.