Discussion
muscle mass, muscular mass, cardiovascular disease, heart disease, MetS, metabolic disorders, dyslipidemia
CARDIOVASCULAR DISEASE, DYSLIPIDEMIA, HEART DISEASE, INSULIN RESISTANCE, METABOLIC DISORDERS, HIGH BLOOD PRESSURE, INSULIN SENSITIVITY, DYSLIPIDEMIA
The findings of the present study imply that 8 weeks of RT and HIIT positively affected the metabolic profile of the participants with MetS compared to the controls. This short-term period of RT and HIIT, along with the reduction of cardio-metabolic risk factors, improved SIRT1 levels in women with MetS. No meaningful difference was discovered between the two exercise groups in their SIRT1 levels. However, HIIT was more suitable than RT in improving cardiorespiratory fitness (Vo2peak) and reducing systolic blood pressure, cholesterol, Hb1AC, and FBS. On the other hand, RT was more effective in increasing muscle mass and strength.Studies on metabolic disorders have sparked interest in the role of mammalian SIRT1 protein (encoded by the SIRT1 gene), as it participates in critical physiological functions such as glucose metabolism and lipid breakdown [Dyslipidemia and cardiovascular disease risk factors are common among patients with MetS. The results of the current study suggest that regular physical activity can improve dyslipidemia and cardiovascular risk factors, in line with the findings of other studies [Moreover, Cuddy et al., after investigating the effect of HIIT exercises on cardiometabolic health indicators of a group of obese middle-aged men and women, reached the conclusion that HIIT exercises have effective improvements on MetS indicators [A major contributor to MetS, insulin resistance is correlated with a greater risk for cardiovascular disease and mortality [One of the major factors that puts individuals at risk of heart disease is high blood pressure [According to the obtained results, the type, intensity, and duration of the exercise program are effective in influencing lipid factors. RT is a powerful anti-aging tool that combats the age-related reduction of myosin heavy chain gene transcripts. It boosts synthesis rate of muscle protein, enhances muscular mass quality and functionality, and promotes better glucose oxidation and insulin sensitivity [