Inclusion Criteria and Study Procedure
depressive disorder, ideation
DISORDERS
Adult outpatients aged between 20 and 64 years who were diagnosed with major depressive disorder based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, with inadequate response to at least 2 different antidepressants with adequate dosage and treatment duration and had a prominent suicidal ideation were enrolled in current study. Participants were randomized into 2 groups receiving a single infusion of either 0.5 mg/kg ketamine or 0.045 mg/kg midazolam (