1. Introduction
DOMS, muscle soreness, EIMD, sarcopenia, muscle damage, Muscle mass, atrophy
ATROPHY, SARCOPENIA
These authors contributed equally to this work.Delayed onset muscle soreness (DOMS) due to intense physical exertion can negatively impact contractility and performance. Previously, NPN_1 (PeptiStrong™), a Muscle mass and sarcopenia are important factors when considering cardiometabolic health, cognitive function, the effect of anti-cancer therapies, as well as improved rehabilitation after injury or orthopaedic surgery and physical independence through ageing. While regular activity and resistance exercise are important parts of maintaining muscle health, exercise-induced muscle damage (EIMD) can occur following intense physical activity and resistance training [Reducing the effects of DOMS is confounded by the molecular complexity, making interventions challenging. Nutritional intervention strategies have had some success addressing biomarker expression of DOMS [Characterising bioactive peptides in a nutrient-dense food source is a time-consuming and serendipitous endeavour, with multiple fractionation steps required [Previously, we have shown that NPN_1 induced an increase in phosphorylated S6 with a concomitant decrease in atrophy associated genes in vitro, with the effects translating into a benefit in a murine model [