Author contributions
NVil
LH-M, M-MR-P, JV and NVil contributed in the conception of the work and wrote the manuscript. RP contributed in the data analysis. BA performed the bioinformatics and statistical analyses. FG-P, NVir and RLP participated in the study design. JO, RM, CL, CS, MP-M, MP-P, SP and SF-V critically revised the manuscript. All authors contributed to the article and approved the submitted version.