4. Discussion
Thirst
BLIND, SIDE EFFECT
Thirst is a subjective feeling that can trigger the desire of the human body to drink water, a manifestation of body imbalance, and one of the important factors influencing the patient comfort.Some studiesMany previous studiesThis study has some limitations that are worth considering. First of all, this study is a single center study, involving a small number of children. Secondly, limited by the research conditions, the effect of this study on ice water and menthol is mainly judged by various scales, and there is still a lack of objective indicators to analyze the treatment effect. Thirst is primarily caused by an increase in fluid osmolality and decrease in blood volume. We did not regularly monitor the plasma osmolality and blood volume unless the children had obvious related symptoms, thus we lacked the data on the plasma osmolality and blood volume. Thirdly, we currently did not find any side effect associated with menthol spray, more long-term studies are needed to further evaluate the safety of menthol spray. Finally, this study did not apply blind methods to patients, nurses and outcome evaluators. It is necessary to conduct more high-quality researches with larger sample in the future to further analyze the effect and safety of ice water and menthol on fasting children.