Introduction
cHCC-CC, HCC, intrahepatic cholangiocarcinoma
PRIMARY LIVER CARCINOMA, RECURRENCE, COMBINED HEPATOCELLULAR-CHOLANGIOCARCINOMA, HEPATOCELLULAR CARCINOMA, INTRAHEPATIC CHOLANGIOCARCINOMA, CHCC-CC
Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare primary liver carcinoma primarily consisting of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) [In the past, numerous models for predicting postoperative recurrence of HCC have been developed based on clinical, pathological, and radiomics characteristics [Given the rarity and poor prognosis of cHCC-CC, identifying the risk factors that influence the prognosis of cHCC-CC and predict its recurrence is crucial. This study aims to analyze the relationship between clinical, computed tomography (CT), and pathological features of cHCC-CC and early recurrence by collecting multicenter data from three institutions. In addition, the study aims to establish and validate a scoring model for early recurrence after cHCC-CC surgery to accurately predict individualized early recurrence and guide clinical decision-making.