Study design and population
asthma, COPD
RESPIRATORY DISEASE, COPD, ASTHMA
This prospective, randomized, parallel and one-way blinded clinical trial, was conducted at Shahid Beheshti Hospital, a teaching hospital affiliated by Kashan University of Medical Sciences (KAUMS), Kashan, Iran; between 2017 and 2019.To recruit the participants, 100 patients with ASA class 1 and 2, aged between 18 and 75 years, who were candidates for PLIF, were assessed. Among them, 22 patients were excluded. Exclusion criteria were: more than 6 planned surgical levels, respiratory diseases like asthma and COPD (Consort flow diagramThe permuted block randomization was used for the participants’ allocation (allocation ratio = 1:1). To do this, a computer-generated list and sealed envelopes were used. All the patients were operated in prone position by one surgeon and a single surgical team using the same method. Although the surgeon and involved nurses were aware of the study, they were blinded to the details of the study’s protocol.