INTRODUCTION
obesity, osteoarticular diseases, Examination Survey‐2016”.This disease, cancer, respiratory diseases, overweight, deaths, hypertension
OBESITY, RESPIRATORY DISEASE, CARDIOVASCULAR DISEASES, HYPERTENSION, CANCER, TYPE 2 DIABETES, DISEASES
Today, obesity is a global epidemy according to the World Health Organization, given the increase in its frequency in the world, and its responsibility in the appearance of several chronic pathologies, such as type 2 diabetes, hypertension, cardiovascular diseases, respiratory diseases, osteoarticular diseases, cancer and other pathologies.In 2021, the WHO announced that more than 40% of men and women, or 2.2 billion people, are overweight and that an unbalanced diet was responsible for at least 8 million deaths per year. It is estimated that by 2025, 167 million people would be at risk of impaired health due to obesity.In Tunisia, the prevalence of obesity was 26.2% in 2016 according to the results of the “Tunisian Health Examination Survey‐2016”.This disease is multifactorial, among the contributing factors of obesity are: a high‐fat diet, a sedentary lifestyle, but also the imbalance of the intestinal flora, “the gut microbiota”Gut microbiota is defined by all the beneficial microorganisms that live and grow in the intestine. It is set up from birth and evolves according to different factors such as antibiotic treatments or diet (presence of fibres, richness of foods in pre and probiotics). Probiotics are living microorganisms, they are bacteria such as Today, the microbiota is considered a therapeutic revolution, where researchers use its enrichment to prevent or treat certain diseases including obesity,Aim: The objective of this interventional clinical trial was to evaluate the effects of a probiotic supplement containing 