Who will take informed consent? {26a}
After having contacted the coordinating center, all patients that indicate interest in the trial will first receive general information on the trial by the study physician (CJvD). If the patients continue to be interested in participating, they receive a copy of the patient information sheet and consent form. If the patient is willing to participate, oral and written consent will be obtained in person by one of the study physicians (CJvD, AD, MN) before initial screening.