Pathological assessments
Becker tumor, tumor, TRG
REGRESSION, TUMOR
Patients who received per-protocol treatment and tumor resection were evaluated for pathological responses. Surgical specimens were stained with hematoxylin and eosin and analyzed by pathologists for the percentage of residual viable tumor cells in tumor beds. Complete pathological response (CPR) was defined as no viable tumor cells. Major pathological response (MPR) was defined with no more than 10% viable tumor cells. Partial pathological response (PPR) and PPR+ were defined as no more than 50 and 30% viable tumor cells, respectively. In addition, tumor regression was also classified using the Becker tumor regression grading (TRG) system