Funding
No competing financial interests exist. The authors had financial support for the submitted work as specified in the funding section, but the funding institutions did not have any role in the writing of the article or the decision to submit it for publication; no financial relationships with any organizations that might have an interest in the submitted work in the previous 3 years; no other relationships or activities that could appear to have influenced the submitted work. This article does not include details, images, or videosrelating to an individual person, requiring specific consent. This work was supported by the National Natural Science Foundation of China (NO. 82030048, 8210219, 82001818, and 82102052), Key Research and Development Program of Zhejiang Province (NO. 2019C03077), Natural Science Foundation of Zhejiang Province (NO. LQ20H180009, Y16H180019, LQ20H180011 and LQ19H180004), Zhejiang Science and Technology Project (LQ21H180007).