Study design and participants
WEST
This was a phase IV, open-label, dual, parallel arm, randomised, multi-centre, feasibility trial comparing MVC plus optimised background therapy (MVC+OBT) versus OBT alone in HIV-NAFLD over 96 weeks. The sites were hospitals in London (Barts, Chelsea and Westminster), the Midlands (Nottingham), North (Liverpool, South Tees), South (Brighton) and West (Bristol) of England.Potentially eligible individuals were identified by members of the direct care team through review of clinic databases, pre-identification of those attending routine consultations and review of medical notes during follow-up. Anonymised information collected on individuals contacted but not randomised were age, gender, ethnicity, reason for lack of eligibility or if they were potentially eligible but declined.Detailed methodology has been presented previously [