Discussion
diabetic mice, T2DM
INSULIN SENSITIVITY
In the present study, daily supplementation of aqueous and ethanolic Hamzeh et al. showed in their study that daily oral intake of a hydroalcoholic Ozbek et al. investigated the efficacy of In the study by Chen et al., several stilbene compounds, including rhaponticin, isolated from rhubarb rhizome extract, and the effects of rhaponticin on glucose and lipid metabolism as well as liver and heart function were investigated in a rat model of T2DM. Rhubarb supplementation significantly decreased serum levels of glucose and insulin, and this supplementation resulted in higher insulin sensitivity in diabetic mice [In an experimental study by Naqishbandi et al., the serum glucose levels of healthy mice decreased after administration of a single dose of One study indicated that rhubarb polyphenols increased insulin-stimulated glucose uptake as well as pioglitazone in adipocytes, suggesting that the active metabolites of rhubarb may enhance insulin action via peroxisome proliferator-activated receptor-γ (PPAR-γ) activation [In this study, we investigated the effect of These apolipoproteins are also a useful indicator for lipid-lowering therapies [Previously, the active constituents of To our knowledge, this study was the first study to compare aqueous and alcoholic extracts of 