Outcome measures
DISEASE PROGRESSION, SECONDARY
The primary outcome associated with oral health was the change in DMFT or the decayed, missing, and filled deciduous teeth (dmft) scores, and the secondary outcome was the viral load. Initially, the CD4 count was considered the secondary outcome. However, after initiating the study, only viral load was used to measure disease progression in children living with HIV in Cambodia. Therefore, viral load was used as the study outcome, as shown in the revised online protocol (ISRCTN15177479). For oral health outcomes, we collected data regarding oral hygiene indicators (salivary pH, salivary flow quantity, debris index score, and oral health-related QOL [OHQOL]) and oral healthcare behavioral indicators (dental visits, brushing frequency and duration, and oral care support from caregivers). To measure the overall health outcomes, we collected information regarding height for age, body mass index (BMI) for age, and overall QOL in addition to viral load.