Questionnaire data
Cancer
CANCER
The KARISMA symptom questionnaire consist of 48 predefined questions including side effects associated to endocrine treatment and more general symptoms potentially affecting the quality of life (Supplementary Methods). Nineteen questions were selected from the validated Functional Assessment of Cancer Therapy - Endocrine Symptoms (FACT-ES Additional Concerns) questionnaire [The instruction for the 26 endocrine-treatment-related questions was “Mark every symptom as it applies to the last 30 days”, whilst for the 22 general symptoms the instruction read “How much did the symptom bother or distress you during the last 30 days”. The MSAS questionnaire also included the dimensions frequency and severity, but those were not included in this analyse since the answer options are not consistent with FACT-ES. For all 48 symptoms, the five-graded Likert scale [Participants answered the web questionnaire at inclusion, at 1-, 3- and 6 months following therapy initiation. Women who discontinued treatment were asked to complete a questionnaire at the date of discontinuation. Participant who did not complete the questionnaire within 2 weeks, received a reminder via phone. Answers from the first and last questionnaire were used in the analyses. Missing answers in the questionnaire were excluded from the analyses.