Sample size calculation
The sample size calculation is based on the expected improvements in the prevalence of resistant hypertension due to improvements in adherence (Supplemental material Figure S1). It was expected that the prevalence of resistant hypertension at t12 improved (i.e. reduced) from 100 to 80% in the intervention+SoC arm due to the intervention and participation in a study and from 100 to 90% in the SoC alone due to participation in the study. The extent of the improvements was based on several previously conducted adherence trials [