2.7. Ethical Considerations
According to the entry and exit criteria of the study, the supplement was found to be safe and entirely ethical for people eligible to enter the present study. In addition, at the beginning of the study, the subject, objectives, and method of the study were explained to the patients. Then, if they were willing to participate, a written informed consent form was completed. All participants were allowed to withdraw at any time and at any stage of the research. We followed the principles outlined by the Declaration of Helsinki at all stages. The study proposal was approved by the Ethics Committee of Shiraz University of Medical Sciences under the code IR.SUMS.SCHEANUT.REC.1400.031. It is also registered with the Iranian Registry of Clinical Trials (