Author contributions
CAH, SJS
RECRUITMENT, CAH
ALA, RR, RAJ, FW, JW, MS, SJS, SJG, JB, CAH and AJH planned and designed the study. RR led on the development of the intervention. FW managed the project, and JW and MS undertook study coordination (recruitment, day-to-day management of the study). JB acted as patient representative. SJS provided statistical input. CB contributed to data management including processing. JM wrote the statistical analysis plan, which all co-authors reviewed critically. JM carried out the analysis and wrote the first draft of the manuscript. All authors reviewed and edited the manuscript before submission.