Introduction
impairment of skin barrier
MALNUTRITION
As the largest organ of the body, skin serves as the interface between the body and the external environment, exerting multiple pivotal protective functions against exposome aggressions, e.g., air pollution, climate stimuli, solar radiation, lack of sleep, malnutrition, etc.The impairment of skin barrier has a huge influence on the quality of life of individuals. Unfortunately, there is no simple regimen to enhance skin barrier function. In some cases, chemicals or steroids, including tacrolimus, trans-4-tert-butylcyclohexanol, phenoxyethanol, pimecrolimus, or corticosteroids, can be used to relieve the symptomsAn increasing number of evidence-based reports advance the hypothesis that certain probiotics are beneficial to the skin immune system, barrier function, and cutaneous microbiota, leading to a health status of skin homeostasisIn our previous study, we validated the efficacy of the fermented lysate from 