WHAT IS ALREADY KNOWN ON THIS TOPIC
rheumatoid arthritis, RA
RHEUMATOID ARTHRITIS, ADVERSE EVENTS
Biological disease-modifying antirheumatic drugs are established components of the treatment of rheumatoid arthritis (RA); however, they are not effective in all patients and can be associated with significant adverse events.Therefore, an unmet need is a treatment for RA at least as effective as current biologicals, but with an improved safety profile.TAS5315 is a Bruton’s tyrosine kinase inhibitor under development for RA.