Statistical Analysis
RP
RECRUITMENT, RECRUITMENT
Power analyses initially conducted independently for each incentive condition (RP and AI) indicated that a sample of 50 participants per medication group per incentive condition was necessary (for a total of 200 participants). Owing to recruitment challenges, a revised power analysis was conducted that collapsed across incentive conditions to evaluate bupropion SR vs placebo, yielding a total of 50 participants per medication group while covarying for incentive conditions. Recruitment ended early due to the SARS-CoV-2 pandemic, with 83 of 100 enrolled participants randomized (83.0%) and 80 participants included in the MITT analyses (80.0%).Demographic and drug use characteristics were compared across groups using χ