Objectives {7}
hernia
The high rate of IH after loop ileostomy closure with its associated morbidity, loss of health-related quality of life and costs (hernia repair, loss of workforce) warrants the investigation of prophylactic measures. Prophylactic mesh implantation at the time of surgical stoma reversal has shown to be a promising and safe method to prevent IH formation in this setting. However, the efficacy of this method has not yet been investigated in a large multicentre RCT with adequate external validity. P.E.L.I.O.N will fill this evidence gap. The aim of the PELION trial is to evaluate the efficacy of prophylactic mesh reinforcement after loop ileostomy closure in decreasing the rate of IH versus standard closure alone.