Response Assessment
inflammation, tumor, breast tumor
INFLAMMATION, TUMOR, BREAST TUMOR, ENLARGEMENT
The breast tumor was measured using calipers in two dimensions at weekly visits on days 1, 8, 15, 22, 29, 36, and 43. No generally acceptable, well-defined criteria for measuring response after intratumoral oncolytic virotherapy exist; apparent tumor enlargement may be seen that can be associated with new or enlarging central tumor cavities or cysts from tumor-cell death, inflammation related to an influx of immune cells (pseudoprogression), or delayed antitumor immune responses (