Clinical management
RDS
POSITIVE
Positive pressure with a neonatal mask and a T-piece system (Neopuff Infant Resuscitator ®, Fisher and Paykel, Auckland, New Zealand) will be used to stabilize the newborns after birth as per routine daily practice. If necessary, infants will start mechanical ventilation in agreement with the European guidelines [To better standardize the timing of care after birth, assistance in the delivery room, transfer of the newborn to the NICU, stabilization of the newborn, and the related procedures (positioning of the vascular access, stabilization of ventilatory parameters, thermal homeostasis, etc.) are expected to be completed within the first hour of life.Once infants with RDS have been screened, enrolled in the study, and assigned to a group (CG or LUSG), LU will be performed as soon as possible between 60 and 180 min of life. In the meantime, patients will be assisted with non-invasive ventilation (nCPAP, positive pressure 6–8 cmH