Background
exacerbations, lung disease, Bronchial thermoplasty, airway inflammation, COPD
ADVERSE REACTIONS, LUNG DISEASE, COPD, DECREASED LUNG COMPLIANCE, HEAT, OXIDATIVE STRESS, PATHOGENESIS
COPD is a common lung disease worldwide [It is currently believed that COPD is chronic airway limitation caused by airway remodeling and decreased lung compliance due to small airway inflammation, oxidative stress and lung parenchymal destruction [Based on the above discussion, the pathogenesis of COPD is quite complex, which involves several links, such as airway inflammation, immunoregulation, airway neuroregulation and airway remodeling, but the precise mechanisms remain to be fully illustrated. The existing therapeutic means and methods cannot achieve satisfactory effects, the lung function of COPD patients shows a gradually declining trend year by year, and repeated acute exacerbations may occur.Bronchial thermoplasty (BT) uses radiofrequency catheter to release radiofrequency energy in the airway wall at a specified location, converts it into heat energy and acts on bronchial smooth muscle cells to ablate the thickened airway smooth muscle layer and reduce airway responsiveness [Recent studies have found the role of BT in airway smooth muscle and airway epithelium, which can reverse airway remodeling [Clinically used drugs for COPD are limited by poor efficacy and adverse reactions [