Introduction
age-related loss of muscle mass, metabolic disorder, sarcopenia, insulin deficiency, hyperglycemia, diabetic, Sarcopenia, disability, diabetes
METABOLIC DISORDER, SARCOPENIA, DISORDERS, HYPERGLYCEMIA, DIABETES MELLITUS (DM), INSULIN RESISTANCE, SARCOPENIA, COMPLICATIONS, DIABETES
Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia resulting from insulin deficiency, insulin resistance, or both. It has become a major global health epidemic with high incidence worldwide. The global prevalence rate of diabetes has been projected to be 8.8% (415 million individuals) in 2015 and this number is supposed to increase to 10.4% (642 million individuals) by 2040 [Sarcopenia, first described by Irving Rosenberg in 1988, is an age-related loss of muscle mass and function disorders, which brings enormous clinical challenge, and burdens of economic and daily life for individual [It has been demonstrated that sarcopenia, an age-related process, is associated with frailty and the microvascular and macrovascular risks of diabetes, which are emerging as severe complications leading to disability and mortality [Recent studies suggest that sarcopenia is a potentially reversible or preventable condition, which means diabetic patients with sarcopenia are assumed to benefit from early diagnosis and early intervention, especially in the early stage of sarcopenia [Considering the impact on the quality of life for people with diabetes, much more attention has been paid to the identification and prevention of sarcopenia in diabetic individuals [