Pathological evaluation
tumor
TUMOR
The immunohistochemistry (IHC) index was assessed based on the core needle biopsy of the tumor. Hormone receptor (HR) positive was defined as estrogen receptor (ER) or progesterone receptors (PR) expressing cells percentage > 1% by IHC. HER2 status was classified according to the IHC score and the result of fluorescence in situ hybridization (FISH). A score of 0 was HER2 negative, a score of 1 + or 2 + without amplification of ERBB2 gene was HER2-low expression, and a score of 3 + or 2 + with ERBB2 gene amplified was HER2 positive. A cut-off value of 1% was used for defining the P53 positive expression [