Levosimendan administration
ADVERSE EFFECTS
All patients in the levosimendan group received a continuous infusion of 0.2 µg/kg/min over 24 h (i.e., 20 mg for a patient of 70 kg) administered as a single dose without an initial bolus of levosimendan according to local standard protocol. Administrated levosimendan was diluted in 0.9% NaCl at a concentration of 0.25 mg/mL, according to the manufacturer recommendations. In this study, none of the patients who received levosimendan exhibited adverse effects requiring cessation of the drug administration before completion of the standard dose.