Study procedure and relevant medications
MLD, stenosis
MLD, STENOSIS
During hospitalization, demographic, clinical, biochemical, and echocardiographic data, as well as medication use, were recorded. All patients were given aspirin (100 mg per day) and clopidogrel (75 mg per day) or ticagrelor (90 mg twice per day) routinely, and a loading dose of clopidogrel (300 mg) or ticagrelor (180 mg) was prescribed 6–24 h before coronary angiography (CAG) and PCI. During PCI, a bolus of bivalirudin (0.75 mg/kg) was administered after insertion of the arterial sheath, followed immediately by an infusion of 1.75 mg/kg/h until completion of the PCI. Bivalirudin was then stopped at the end of PCI or prolonged in accordance with the treatment group. In addition, PCI-related data were recorded. After PCI, all patients were advised to take aspirin (100 mg per day) for life and clopidogrel (75 mg per day) or ticagrelor (90 mg twice per day) for at least 12 months according to current guidelinesAfter injection of 200-μg nitroglycerin into the coronary artery, using the guiding catheter for calibration, the end-diastolic lesion length (LL), minimum luminal diameter (MLD), reference vessel diameter (RVD), and percentage of diameter stenosis (DS) were measured before and after ePCI. CAG was performed in all patients, and CAG data were analyzed by an experienced technician blinded to the patient groups.