Additional consent provisions for collection and use of participant data and biological specimens {26b}
STEC infection
A key tenet of this study is that clinical care is a clinical decision with children receiving care in accordance with the pathway allocated to the site. However, prior to collecting any patient data or biospecimens, informed consent is required along with assent as appropriate. To enable this approach, once a child is identified as being pathway eligible, a member of the clinical care team will provide patients/caregivers with an information sheet (Illustration of the participant flow through the study. Clinical decision point: patients and caregivers are presented with the standard medical risks associated with STEC infection, the known pros/cons of available treatment options, and the treatment currently recommended due to the study allocation. Research decision point: patients and caregivers can consent to data and biospecimen collection