Randomization and Interventions
Randomization was performed via a centralized web application designed by MORU software engineers using RShiny, hosted on a MORU webserver. The control arm comprised a minimum proportion of 20% of patients with uniform randomization ratios applied across the treatment arms. All patients received standard symptomatic treatment. Remdesivir (Covifor: Hetero Drugs Ltd, Hyderabad, India [in Thailand, n = 58], and Veklury: Gilead Sciences, Foster City, California [in Brazil, n = 9]) was given by rate-controlled intravenous infusion over 60 minutes (reconstituted and added to 250 mL 0.9% saline) in an initial adult dose of 200 mg, followed by 100 mg once daily for 4 days to complete a 5-day course (