Author contributions
The sponsor, Acadia Pharmaceuticals, and J.L.N., A.K.P., T.A.B., E.M.B.-K. and D.G.G. conceived and designed the study; all authors conducted the study and collected data, performed the formal analysis, participated in data interpretation, critically revised the manuscript content for important intellectual content, approved the final version and agreed to be accountable for all aspects of the work.