Study population and data collection
T2DM, CVD, Diabetes
CVD, SECONDARY, DIABETES
The current study is a secondary analysis of data generated in a randomized controlled trial (the Action to Control Cardiovascular Risk in Diabetes [ACCORD] study) of 10,251 patients with T2DM and CVD or at a high CVD risk. The study, conducted at 77 clinical centers across the United States and Canada, employed a randomized, double 2×2 factorial design; it aimed to investigate the potential benefits of enhanced control over blood glucose, blood pressure, and/or lipid levels in improving cardiovascular outcomes among patients with T2DM. This trial’s design and main study outcomes have been previously published (