Ethics approval and informed consent to participate
Ethical approvalwas obtained from the nine relevant human research ethics committees, listed below. All participating patients provided written, informed consent to participate. All methods were carried out in accordance with the relevant guidelines and regulations.Hunter New England HREC (New South Wales; reference LNR/12/HNE/390).St Vincent’s Health and Aged Care HREC (Queensland; reference HREC #13/10) and The Prince Charles Hospital HREC (Queensland) Austin Health HREC (Victoria; reference LNR/14/Austin/208 LNRR MAP) Barwon Health HREC (Victoria; reference 13/82).Epworth HREC (Victoria; reference LR138–13) Calvary Health Care Clinical and Research Ethics Committee (Tasmania; refer- ences 2:05:13 and 5:13:12) Calvary Healthcare Adelaide HREC (South Australia; reference 13-CHREC-E007) The Hunter New England Research Ethics Committee (New South Wales, refer- ence 16/07/20/5.05, 11 July 2016) Macquarie University HREC (New South Wales, reference 5201600658, August 2016).