Author Contributions
G.d.S.R., K.P.R., M.L.d.A. and N.Y.N. conceptualized and designed the study; S.d.S., J.A.L.R., C.R.B.J. and G.d.S.R. collected clinical data; G.d.S.R., K.P.R., M.L.d.A., A.C.d.S.S., N.Y.N., S.d.S. and J.A.L.R. performed the tests; C.R.B.J., N.Y.N. and G.d.S.R. provided laboratory support and supervised experiments; G.d.S.R., N.Y.N., S.d.S. and J.A.L.R. performed data analysis; M.L.d.A., A.C.d.S.S., N.Y.N., C.J.R.B. and G.d.S.R. drafted the manuscript. All authors interpreted the data, participated in manuscript review, and approved the final manuscript. All authors have read and agreed to the published version of the manuscript.