Introduction
Gastric cancer, Upper gastrointestinal endoscopy, gastric cancers, upper gastrointestinal neoplasms, deaths
GASTRIC CANCER, GASTRIC CANCERS, GASTRIC NEOPLASMS, BLIND, GASTRIC CANCER
Gastric cancer is the fourth leading cause of cancer-related deaths, with an estimated 1,080,000 new cases and 760,000 deaths in 2020 [Upper gastrointestinal endoscopy is widely used to detect and diagnose early gastric cancers [Despite its diagnostic ability, the quality of endoscopic examination plays an important role in the detection of EGC, which is a prerequisite for lesion detection [With the rapid progress in artificial intelligence (AI) technology, several researchers have developed intelligent systems aimed at diagnosing EGC or upper gastrointestinal neoplasms, and few studies have aimed to ensure the completeness of examinations [Development of a tool with the ability to simultaneously improve the diagnostic performance of WLE and ensure high completeness of examination is an ideal way to fulfil these needs. Therefore, we proposed the AI system ENDOANGEL-GC (gastric cancer), which simultaneously combines the functions of blind spot monitoring and lesion detection and runs in real time. We designed this randomised, controlled, patient-blinded, multi-centre trial with two parallel groups and a 1:1 allocation to evaluate the hypothesis that ENDOANGEL-GC would improve the detection rates of gastric neoplasms and EGC.