Study Population
epicardial stenosis, chronic angina, ischemia, pulmonary or kidney disease, microvascular dysfunction
ATRIOVENTRICULAR BLOCK, ISCHEMIA, VALVULAR HEART DISEASE, CARDIOMYOPATHY
Patients had chronic angina (Canadian Cardiovascular Society 2-4) without epicardial stenosis, reversible ischemia on noninvasive testing, and evidence of microvascular dysfunction (index of microvascular resistance [IMR] ≥25 mm Hg × s). Main exclusion criteria were second- or third-degree atrioventricular block, any valvular heart disease, any cardiomyopathy, and pulmonary or kidney disease.