Design
The efficacy trial was a 26-week double-blind parallel group multi-centric RCT. Participants were randomized to either the SFL home-based computerized multidomain intervention or a home-based active control intervention. Outcome measures were collected at pre-training (PRE; within 6 weeks prior to the start of the intervention) and post-training (POST, within 4 weeks following the end of the intervention). Randomization was done independently from the research team with a 1:1 ratio stratified based on the frailty status using REDCap. Participants were blinded to the nature of their intervention (experimental vs comparator), and assessors were blinded to the hypotheses and the participants’ assignment. Statistical analyses were blinded to the intervention condition.