Study design
PCOS
This RCT was carried out on the 116 infertile women who underwent IVF in the Reproductive Biomedicine Research Centre at ROYAN Institute, Tehran, Iran (November2016-May2019). Our study was registered in the international Clinical Trial Website (ClinicalTrials.gov Identifier: NCT03876145). Retrospectively registered at 15/03/2019.All patients were counseled about the nature of the study and randomization procedure. Also all participants sign consent form and they may drop out of the study at any time. Participating patients were registered in our local ethical committee register that approved the study, and all methods were performed in accordance with the relevant guidelines and regulations.Due to the lack of a similar study, this pilot study was conducted on four equal-sized groups, each with 30 patients with PCOS. Block randomization method is designed by epidemiologist using STATA software version 13 and the number of blocks considered is 8. The random allocation list for patients is solely available to the epidemiologist. In order to hide the random allocation process, a total of 120 envelopes are prepared, and only the methodologist has been aware of table of random numbers. When the doctor declared the patient’s eligibility, the methodologist provided the doctor with the envelope. The group will be selected and based on the type of group mentioned in the envelope. Each patient participated in the study only once.Based on the Rotterdam Criteria [