Conclusions
HBP
In conclusion, subcuticular suture might offer a certain decrease on si-SSI incidence, compared to conventional staples, for skin closure after elective HBP surgery. However, this difference is found not to be not statistically significant and thus, wound closure strategy should not be based on these grounds. Either subcuticular suture or surgical staples can be considered routine method for wound closure in HBP elective surgery, albeit individual patient characteristics and particular preferences should also be considered. Considering all this clinical data and the pragmatic evidence of the present randomized controlled trial, the authors consider no further need for additional randomized studies to address this issue. Future studies should focus on aggregated data analysis comparing clean surgery against clean-contaminated and contaminated surgery.