Introduction
postnasal, Hypersensitivity pneumonitis, fatigue, worrisomeRhinosinusitis, allergic rhinitis, nasal blockage, pain, ageusia, anosmia, cough, respiratory diseases, asthma, immune-mediated reaction, chronic respiratory airway diseases, interstitial lung disease, COPD
RESPIRATORY DISEASE, AIRWAYS DISEASE, BRONCHIECTASIS, HYPERSENSITIVITY PNEUMONITIS, CHRONIC RHINOSINUSITIS, ALLERGIC RHINITIS, COPD, ASTHMA, INTERSTITIAL LUNG DISEASE
Hypersensitivity pneumonitis is an interstitial lung disease developed from an immune-mediated reaction in predisposed and sensitized individuals to a large variety of inhaled organic and inorganic antigensInitial observations of the coexistence of allergic rhinitis, chronic rhinosinusitis, and asthma led to the formulation of the concept of united airways diseases (UAD)Furthermore, there is increasing evidence that the UAD concept also applies to other chronic respiratory airway diseases, such as COPD, bronchiectasis, and cystic fibrosisIn both acute and chronic rhinosinusitis, the most severe and prevalent symptoms are nasal blockage, facial pain, anosmia, ageusia, and postnasal discharge. In addition, fatigue and arousing up exhausted are prevalent and worrisomeRhinosinusitis as well has impacted the quality of life in a significant percentage of HP patients as it aggravates their cough. Treatment of cough, whenever possible, is targeted at the treatment of the underlying interstitial lung disease in addition to targeting co-factors such as rhinosinusitisAs sinonasal symptoms add to the burden of respiratory diseases and impair patients' quality of life as well as that the main purpose of the diagnosis of ILD is to make an assured diagnosis using the least invasive approach. So, the purpose of this study was to assess the burden of sinonasal symptoms in HP patients and to study nasal histopathological changes in order to identify any shared pathological changes between the upper airways and the well-known pathological features of HP.