2.3.2. Secondary Outcomes
anxiety, fatigue, pain, adiposity, morning tiredness, depression
SENSITIVITY, ADIPOSITY, FIBROMYALGIA, CREST, FMS
Basal blood samples of GH: Serum samples for the hormonal analyses were drawn between 10.00 h. and 10.30 h. The blood samples were obtained from the antecubital vein. Plasma GH was measured by an immunoradiometric assay, with a sensitivity of 0.1 µg/L and with Intrassay coefficients that varied between 6.3% and 4.4% for GH concentrations of 2.2 µg/L and 2.4 µg/L, respectively.Sensitivity to pain: To assess the variation in the perception of pain at each one of the points described by the ACR criteria, the method applied by Alegre et al. (1995) as cited in [Anthropometric and body composition measurements: The anthropometric variables were taken by an experienced physiotherapist. Weight, sex, body mass index (BMI), abdominal perimeter and adiposity index (sum of the six skinfold measurements of fat) were evaluated. Skinfold fat was measured at the triceps, subscapular, iliac crest, abdominal, front thigh, and medial calf locations using Holtain skinfold callipers [Physical performance: Maximum oxygen uptake (VOHealth-related quality of life: The health-related quality of life was assessed by means of The Fibromyalgia Impact Questionnaire (FIQ) and the EuroQol five-dimensional questionnaire (EQ-5D). The FIQ is a self-report inventory that includes 10 items to specifically measure FMS patient’s ability to perform physical activities, the number of days in the last week that they felt good and how many days of work they missed, as well as their ability to work, pain, fatigue, morning tiredness, stiffness, anxiety, and depression. The total score ranges from 0 to 100, and higher scores indicate greater functional difficulties. The Spanish validated version of the FIQ was used, which has demonstrated appropriate psychometric properties [