Trial design {8}
CF, PEx
The PEx core protocol describes the establishment of a prospective, multi-site cohort that is intended to perpetually enroll children and adults with CF to serve as an adaptive platform for evaluating the (comparative) effectiveness of interventions for PEx, including through cohort-nested sub-studies. The PEx cohort is intended to be representative of the total CF population (Fig. The relationship between the BEAT CF cohort and nested substudies