Study products
Test products used in this study were provided by Dyne Bio Inc.(Sungnam, Korea). As described in previous studies [
Representative chromatograms of NAOs based on high-performance liquid chromatography (HPLC) analysis of Neoagarotetraose (DP4) and Neoagarohexaose (DP6)The 3 g/day dose is based on our preclinical studies [All subjects were randomly assigned to a group administered with NAOs (3 g/day of NAOs) or a placebo group (0 g/day of NAOs). Subjects took 3 g per day (twice after breakfast and dinner, four capsules once) for 16 weeks. The placebo capsules contained corn starch with the same weight, energy, carbohydrate content and appearance as the test capsules (Table 
Composition of the test productsNAOs, Neoagaro-oligosaccharides