Pharmacokinetics
BLOOD
Blood was collected to measure plasma zuranolone concentrations at predefined time points and analyzed at a centralized laboratory. For single‐dose measurements in Parts A, B (Periods 1 and 2), and C (Periods 1, 2, and 3), blood was collected predose (0 h) and 0.5, 1, 2, 3, 4, 5, 6, 8, 10, 12, 24, 36, 48, and 72 h after administration. For multiple‐dose PK assessments in Part A, blood was collected predose and 0.5, 1, 2, 3, 4, 12, and 16 h after administration on Day 4; predose on Days 5, 7, 8, and 9; and predose and 0.5, 1, 2, 3, 4, 12, 16, 24, 36, 48, and 60 h after administration on Day 10.The following PK parameters were evaluated: maximum plasma concentration (