Prior distributions and model hierarchy
The following subsections outline the prior distribution structure for the parameters of the model using a Bernoulli distributed endpoint and logistic link function, including the primary model. The model for alternatively distributed endpoints will require an alternative prior structure, which will be described in detail in an openly available, domain-specific statistical analysis plan that will be published prior to the closure of a domain for terminal analysis. For clarity, a simplified graphical model is provided for the primary endpoint in Fig. Graphical model of primary endpoint (simplified to intervention parameters only). IG, inverse-gamma
Prior distributions and model hierarchyIn-text priors are cross-referenced by the first column parentheses