Clinical characteristics of the study subjects
Graves’ ophthalmopathy
In total, 458 patients were screened, and 279 of them met our inclusion criteria and were enrolled in the study. Out of these, 270 subjects completed the study, while nine patients dropped out (two were lost to follow-up, three switched to propylthiouracil due to their desire for pregnancy, one female refused to continue taking contraceptives, and three withdrew consent due to fear of side effects). These nine patients were considered as non-responders and included in the intention-to-treat analysis. Flow chart of the study periods and participants.Comparison between the studied groups regarding demographic data, thyroid profile, and Graves’ ophthalmopathy.N, Number of patients; ATD, Antithyroid drugs; SBP, Systolic blood pressure; DBP, Diastolic blood pressure; FT4, free T4; FT3, free T3; TSH, thyroid stimulating hormone; WBCs, white blood cells; ALT, alanine transaminase.; AST, Aspartate transaminase.