Statistical methods
ADVERSE EVENTS, REGRESSION
Baseline characteristics, incidence and severity of adverse events will be summarized. The number and percent of subjects achieving objective responses (CR or PR) will be summarized along with corresponding two‐sided 95% CI using binomial distribution. Median PFS and OS will be calculated based on the Kaplan–Meier method and compared by log‐rank test. Cox proportional hazard regression model will be used to identify independent prognostic factors.