Discussion
dyspnea, expiratory difficulties
In this study, the observed EEP in adults was different (either higher or lower) from that in earlier studies [Sex also has a significant effect on nasal airway pressure. The EEP was higher in women than in men in our study, and this difference between the two sexes was more significant with increasing nasal cannula size and flow. Groves et al. [Race and age may also have an impact on the EEP, although these variables were not explored in our study. Corey et al. [Although an increased inner diameter of the nasal cannula leads to increase the pressure in the nasal airway, it also results in more expiratory difficulties. Previous studies have shown that the most predominant discomfort associated with HFNC oxygen therapy in healthy adult volunteers in the awake state is dyspnea [Chikata et al. [This study is limited by the fact that it was conducted on healthy volunteers rather than patients. Differences in comfort levels are likely to be present between patients and healthy volunteers. The comfort level may be the result of a combination of various physiological mechanisms [