Ethics and dissemination
KC21FNSI0177
All study procedures were approved by the Institute Review Board of three hospitals (approval numbers: SMC-2021-01-090, 2021AN0104 and KC21FNSI0177). The trial is registered on clinicaltrials.gov (approval ID: NCT05046756). The study protocol was reviewed by the institutional review board of Samsung Medical Center on 1 Feb 2021 and was approved on 23 Feb 2021 as original protocol. In the case of important protocol modifications, principal investigator will share them with coordinating investigators and trial participants, and report to the institutional review board.Personal information about enrolled participants will be collected, shared with clinic (i.e., Korea University Anam Hospital and Seoul St. Mary’s Hospital), and retained only by the research team during study. After the end of the study, all personal information will be retained for 3 years and subsequently destroyed.The trial results will be published in the journal and report of results will be posted on the funding institute’s site for the public, participants, and healthcare professionals.Any publications containing the results of this study have not been already published or submitted to any journal.