Funding
The OPTIMA study was supported by the Canadian Institutes of Health Research (CIHR) through the Canadian Research Initiative in Substance Misuse (CRISM; Grant Numbers CIS-144301, CIS-144302, CIS-144303, CIS-144304). The four nodes of CRISM received independent funding through CIHR priority-driven initiatives (Grant Numbers SMN-139148, SMN-139149, SMN-139150, SMN-139151). The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. M. Eugenia Socias is supported by a MSFHR/St. Paul’s Foundation Scholar Award. Didier Jutras-Aswad holds a research scholar award from the Fonds de Recherche du Québec en Santé. Bernard Le Foll is supported by a clinician scientist award from the Department of Family and Community Medicine and by the Addiction Psychiatry Chair of the Department of Psychiatry, University of Toronto. Bohdan Nosyk is supported by a MSFHR Scholar Award.