Total viable nucleated cells and characterization of the ADSVF
skin ecchymosis, disability, pain
ADVERSE EFFECTS
*ADSVF: Adipose Derived Stromal Vascular Fraction Median (min-max)The abilities to adhere to plastic and differentiate to adipocytes are presented in At the completion of ADSVF administration, the digits did not exhibit capillary filling, but circulation was reestablished itself after two hours without any treatment. There were no immediate or late adverse effects in the hands treated. In the donor site mild pain was reported by all patients and some of them had skin ecchymosis, which improved after 4–5 postoperative days. The total time of this procedure including harvesting of the fat grafts, ADSVF processing and its injection into the hands was 120 minutes.Digital oximetry (SpO2), digital total active motion, thumb opposition, hand function, health status and disability index, and nail capillaroscopic pattern were similar in the two groups at the study’s end.In the experimental group, the pain score increased from 4.6 to 7.5 in the first week, gradually decreased to reach the basal value at day 21, and subsequently began to decrease further (p<0.01). In the control’s group the pain decreased but without significance. For a better visual perception of pain evolution we have made a graphic representation (