Author contribution
MH, FHH
SK designed the trial and the eCRF, led the trial as Principal Coordinating Investigator, contributed patient data, analyzed the data, wrote the manuscript, and edited the manuscript. SI designed the trial and the eCRF, managed the trial together with SK and THB, contributed patient data, analyzed the data, wrote the manuscript, and edited the manuscript. DWolf, FHH, AH, PS, MG, DWolleschak, UP, KD, PJJ, SP, MS, NVB, FS, MC, and DG contributed patient data, analyzed the data, and edited the manuscript. AM performed the JAK2 allele ratio assessments, analyzed the data, and edited the manuscript. MK acted as the CTC-A project manager for the trial, analyzed the data, and edited the manuscript. JFranklin, JFrank, and MH analyzed the data, performed the statistical analysis of the trial, and edited the manuscript. THB designed the trial, led the trial as Co-Principal Coordinating Investigator, contributed patient data, analyzed the data, and edited the manuscript.