Introduction
deficiencies of the hematopoietic system, herpes virus specific T cells, hematologic malignancies, immunodeficiency of the host
DISEASE, HEMATOLOGIC MALIGNANCIES
Edited by: Christian Muenz, University of Zurich, SwitzerlandReviewed by: Enrico Maffini, University of Bologna, Italy; Maria Teresa Lupo Stanghellini, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), ItalyAllogeneic stem cell transplantation is used to cure hematologic malignancies or deficiencies of the hematopoietic system. It is associated with severe immunodeficiency of the host early after transplant and therefore early reactivation of latent herpesviruses such as CMV and EBV within the first 100 days are frequent. Small studies and case series indicated that application of herpes virus specific T cells can control and prevent disease in this patient population.