Integrated study population
CHRONIC KIDNEY DISEASE
Data were obtained from seven randomized, placebo-controlled, dose ranging, phase 2 trials for six GalNAcBaseline Characteristics of the Total Study PopulationASO, antisense oligonucleotide; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration (calculation); eGFR, estimated glomerular filtration rate; LLN, lower limit of normal; SD, standard deviation; ULN, upper limit of normal.Medical History and Concomitant Medications for the Total Study PopulationHMG CoA, 3-hydroxy-3-methylglutaryl coenzyme-A.The monthly dose regimen cohort consisted of 318 subjects (placebo, 