Secondary Outcomes
posturing, mannerisms, hallucinatory behavior, delusions
REMISSION, SYNDROME, POSITIVE, POSTURING
Abbreviations: MPGT, multigenetic pharmacogenomics–guided treatment; OR, odds ratio; TAU, treatment-as-usual.Early response was defined as a percentage Positive and Negative Syndrome Scale score change of 20% or more at the end of postrandomized week 2.Response was defined as a percentage Positive and Negative Syndrome Scale score change of 50% or more at the end of postrandomized week 6.Symptomatic remission was defined as a Positive and Negative Syndrome Scale score of 3 or less on items P1 (delusions), P2 (conceptual disorganization), P3 (hallucinatory behavior), N1 (blunted affect), N4 (passive/apathetic social withdrawal), N6 (lack of spontaneity and flow of conversation), G5 (mannerisms and posturing), and G9 (unusual thought content) at the end of week 12.