One month phase 2 prebiotic/metformin showed distinct gut microbiota shifts
To explore the changes with longer interventions of prebiotic and metformin use in a real-world setting, we compared one month Phase 2 metformin/prebiotic to one week Phase 1 metformin/placebo (Microbiome signatures in Phase 2 prebiotic/metformin vs metformin/placebo. Microbiome signatures in Phase 2 prebiotic/metformin compared to Phase 1 prebiotic/metformin. Compared to Phase 1 metformin/prebiotic, the Phase 2 metformin/prebiotic was associated with changes in microbiome beta-diversity but not alpha-diversity (