Discussion
caries arrest, caries, arrest, systemic infections
DENTAL CARIES, CARIES, ARREST, SYSTEMIC INFECTION, DISEASES
In this randomized clinical trial of SDF vs dental sealants, an experimental treatment of SDF and fluoride varnish was noninferior in the 2-year arrest and prevention of dental caries compared with a standard active comparator, a package of glass ionomer sealants and atraumatic restorations and fluoride varnish. The arrest rate for the experimental treatment was considerably higher than for the active control, and the upper bound for the arrest difference of 0.01 nearly demonstrated superiority.Without proper and timely intervention, dental caries and other oral diseases can lead to severe systemic infections,Overall, we showed that SDF and sealants had an approximate 80% caries prevention rate and 50% caries arrest rate after 2 years. These findings are comparable to those from other more controlled clinical studies, which indicated no differences in the 6- and 12-month caries arrest rates comparing SDF vs atraumatic restorative treatment.