NAbs against live omicron BA.1 subvariant
The NAb GMTs against live omicron BA.1 of the low-dose and the high-dose aerosolised Ad5-nCoV groups were 51.98 (95% CI 37.23, 72.58) and 23.07 (95% CI 15.68, 33.95) at day 28, 27.86 (95% CI 18.81, 41.26) and 23.27 (95% CI 16.24, 33.35) at month 3, 16.00 (95% CI 10.88, 23.53) and 11.99 (95% CI 8.55, 16.81) at month 6, respectively. In the low-dose aerosolised Ad5-nCoV group, the NAb GMT against live omicron BA.1 declined by 46.60% and 69.22% at 3 and 6 months, respectively, compared with the peaking levels at day 28. While, in the high-dose aerosolised Ad5-nCoV group, the NAb GMT increased by 0.87% (23.27 [95% CI 16.24, 33.35]) at month 3 and decreased by 48.03% (11.99 [95% CI 8.55, 16.81]) at month 6, compared with those at day 28 (