Statistics
Values are summarized as mean (standard deviation) or median (interquartile range). Continues data of normal distribution were compared using students t-test. Within-individual comparisons between baseline and follow-up echocardiographies were performed using the paired t-test. Fisher’s Exact test was used to compare categorical variables. Mean difference in changes was calculated as the between group difference in paired estimates to control for random differences in baseline measurements. Thus, the presented results represent absolute changes between study groups. Estimated differences are presented with 95% confidence intervals (95%CI). General linear models were used to assess the correlation between p-K and echocardiographic measurements and presented with R