Ethics approval and consent to participate
This study was approved by the Research Ethics Committee of Aja University of Medical Sciences, Tehran, Iran (ID: IR.AJAUMS.REC.1400.006). Written informed consent was obtained from all subjects after receiving an explanation of the study. All the ethical provisions of the Declaration of Helsinki for human samples were observed. The patients received all health care services provided to other counterparts and were not charged any fees for their participation in the study. They further entered the study voluntary and could withdraw. The patients were even assured that all the data would be kept confidential, and they will be protected from any harm, loss, and bribery during the study.