Trial profile.
HL Hodgkin lymphoma, CMT
Abbreviations: CMT combined-modality treatment, PET-2 positron emission tomography after two cycles of chemotherapy, HL Hodgkin lymphoma, ITT intention-to-treat, PP per-protocol. *Deauville score 1–2. **Deauville score ≥3.With a median follow-up of 64 months, estimated 5-year PFS in the PET-2-negative per-protocol population was 94.2% (91.6–96.9) with CMT and 86.7% (82.5–90.9) with ABVD alone (Fig. 