Ascorbate levels and secondary outcomes
We collected blood samples from 18 patients (from the 1st patient to 18th patient). As shown in Fig. Plasma ascorbate concentration during the first 24 hCompared with placebo, the decrease in vasopressor dose over time was significantly different with a − 0.04 µg/kg/min greater decrease over time (Norepinephrine equivalent changes from baseline to 24 hSOFA score changes from baseline to 72 h