Ethics approval and consent to participate
knee joint osteoarthritis
The study “Evaluation of safety and efficacy of intra-articular transplantation of allogeneic adipose derived mesenchymal stromal cells in patients with knee joint osteoarthritis an interventional randomized triple-blind placebo controlled clinical trial phase I/II” was approved by the ethics committee of Royan institute on October 10, 2017, with the reference number of IR.ACECR.ROYAN.REC.1396.138. The study included only adults, and written informed consent has been obtained from the patients. All procedures were conducted in accordance with the relevant approved regulations, guidelines, and the Declaration of Helsinki.