Conclusion
MDD, depressive, depression, anxiety
REMISSION, DISORDERS
This study provides evidence that the addition of UP on TAU can be efficacious for patients with depressive and/or anxiety disorders in reducing depression. Specifically, our results strengthen the evidence of UP for patients with a principal diagnosis of MDD. Because our results regarding treatment response, remission, and loss of diagnosis were weak, future studies need to investigate strategies to enhance these aspects, for example, by examining moderating and mediating factors.