Safety/toxicity management
tumour
ADVERSE EVENTS, RSI, TUMOUR
ICI stimulate a host immune response against tumour cells. They can also lead to activation of self-reactive T cells that can damage healthy tissue and result in immune related adverse events (ir-AEs) which can affect any body system. A current list of ir-AEs is available to investigators in the Reference Safety Information (RSI). ir-AEs should be managed as per local and national/international guidelines.