Discussion
ABI, RAP
ADVERSE EFFECTS
In the present clinical, prospective study, the main finding was that most of the patients with ABI had no adverse effects of LPV, neither on ICP nor on PRx, independent of PEEP levels applied in this study. However, nearly one-quarter of the patients exhibited a transient rise in ICP during the intervention, requiring it to be interrupted. The high PEEP strategy was as expected associated with higher TPPStudies dealing with the influence on ICP of various types of MV and associated PEEP levels remain inconclusive [To date, no prospective phase III clinical trials showing a better outcome with multimodal neuromonitoring have been published [The modest increase in RAP observed during the intervention periods, suggesting a slightly decrease in cerebral compliance, was consistent with a small and clinically unimportant increment of ICP. rSO