Variables of interest
bleeding, chronic kidney disease, bowel fistula, abdominal pain, chronic pulmonary disease, cholangitis, necrotising, abdominal rigidity, atrial fibrillation, diabetes
MULTIPLE ORGAN FAILURE, BLEEDING, ISCHAEMIC HEART DISEASE, ACUTE PANCREATITIS, CHOLEDOCHOLITHIASIS, CHOLANGITIS, CHRONIC PULMONARY DISEASE, ATRIAL FIBRILLATION, DISEASES, PANCREATIC NECROSIS, COMPLICATIONS, DIABETES
For each patient, the following variables were analysed retrospectively to find possible associations between IPN and mortality risk or ICU admission.1. Demographic data and baseline characteristics: sex, age, COVID-19 status on admission, previous episodes of biliary AP, CCI, BMI, clinical history of diabetes, chronic pulmonary disease, arterial hypertension, atrial fibrillation, ischaemic heart disease, chronic kidney disease, diseases of the haematopoietic system, immunosuppressive medications;2. Clinical risk scores calculated within 72 h from hospital admission: quick Sequential Organ Failure Assessment score (qSOFA), Bedside Index for Severity in Acute Pancreatitis (BISAP), Glasgow-Imrie, Ranson, Acute Physiology and Chronic Health Evaluation II (APACHE II);3. Stage of the AP according to RAC, and systemic organ complications, including single or multiple organ failure within 72 h from hospital admission (haemodynamic, renal, respiratory);4. Vital parameters: temperature, systolic blood pressure, heart rate, respiratory rate, and blood oxygen saturation;5. Laboratory data: white blood cell (WBC) count, neutrophils, platelets, international normalised ratio (INR), CRP, aspartate aminotransferase (AST), alanine aminotransferase (ALT), bilirubin, serum amylase, serum lipase, lactate dehydrogenase (LDH), procalcitonin, lactate;6. Abdominal findings: diffuse abdominal pain, diffuse abdominal rigidity, localised abdominal pain, localised abdominal rigidity;7. Concomitant findings: choledocholithiasis, acute cholangitis, timing and type of interventional procedures (ERCP/ES, endoscopic drainage of pancreatic necrosis, percutaneous drainage and minimally invasive necrosectomy, open surgical necrosectomy);8. Occurrence of complications: ACS, bleeding, bowel fistula, and necrotising cholecystitis;9. Type of supportive care: antibiotic therapy, antifungal therapy, and nutritional support.