EORTC QLQ-C30
TTD
Based on the repeated measures mixed-effect model, there was no clinically meaningful overall change from baseline in GHS/QoL (estimated mean −9.44; 95% CI, −13.11 to −5.77). The median time to definitive deterioration (TTD) was not estimable, and the 6-month probability of not experiencing a definitive deterioration in GHS/QoL was 59.4%. Based on the repeated measures mixed-effect model, there was no clinically meaningful overall change from baseline in nausea/vomiting (estimated mean 7.36; 95% CI, 4.67-10.05). The median TTD was not estimable, and the 6-month probability of not experiencing a definitive deterioration in nausea/vomiting was 81.8%.