Study design and patients
ThIlo, critically ill, ARDS
RECRUITMENT, SECONDARY, ARDS, CRITICALLY ILL
The present study was a secondary analysis of the ThIlo trial, a prospective randomized multicenter trial assessing the efficacy of inhaled iloprost for the prevention of the development and progression of ARDS in critically ill patients. Study design and recruitment are described elsewhere [Iloprost treatment did not show any significant effect on the outcomes of these patients; therefore, a secondary analysis was performed.