Lipid and glycemic profile evaluations
fasting blood glucose, TG
BLOOD, INSULIN RESISTANCE, INSULIN RESISTANCE
The results of serum metabolic indices assessment during the study for each study group are presented in Table In this study, following the diet plan and supplemental interventions, fasting blood glucose levels (FBS) (0.32 ± 0.07 and − 5.28 ± 1.36 mg/dl in the placebo and PP groups, respectively), triglyceride to glucose ratio (-0.008 ± 0.11 and − 0.16 ± 0.11 in the placebo and PP groups, respectively), total cholesterol (TC) (3.21 ± 0.95 and − 10.51 ± 0.77 mg/dl in the placebo and PP groups, respectively), triglyceride (TG) (0.27 ± 0.96 and − 16.02 ± 1.7 mg/dl in the placebo and PP groups, respectively), low-density lipoprotein-cholesterol (LDL-C) (1.40 ± 2.90 and − 9.33 ± 6.66 mg/dl in the placebo and PP groups, respectively), and cholesterol to lipoprotein ratio (0.009 ± 0.21 and − 0.74 ± 0.73 in the placebo and PP groups, respectively) were significantly decreased in pomegranate peel group (All P < 0.001 except from FBS (P = 0.02)). Additionally, serum HDL-C levels (0.70 ± 0.18 and 5.10 ± 0.36 mg/dl in the placebo and PP groups, respectively; P < 0.001) were significantly increased in individuals who received the pomegranate peel. Moreover, after adjusting for potential confounders, physical activity, and energy intake, the mean changes remained significantly greater in the pomegranate peel group than in the placebo group. Changes in fasting insulin (2.78 ± 1.57 and 1.73 ± 2.27 µIU/ml in the placebo and PP groups, respectively; P = 0.81) and homeostatic model assessment for insulin resistance (HOMA-IR) (0.39 ± 0.68 and 0.83 ± 1.20 in the placebo and PP groups, respectively; P = 0.93) were not significantly different when comparing two groups during the study in raw and even adjusted model.
Lipid and glycemic profile changes of placebo and PP groups during the studyData is presented as Mean ± SD.P and P** are extracted from 2 independent sample t test. P* is extracted from paired t test for raw model. Also, P# is presented adjusted model by baseline values, and potential confounders including weight, energy intake and physical activity, with ANCOVA.“Changes” represent before and after changes in raw model; “PP” is for Pomegranate Peel group.Chol: Cholesterol, dl: Deciliter, FBS: Fasting Blood Sugar, HDL-C: High Density Lipoprotein- Cholesterol, HOMA-IR: Homeostatic Model Assessment for Insulin Resistance, µIU: Micro International Unit, mg: Milligrams, ml: Milliliter, LDL-C: Low Density Lipoprotein- Cholesterol, TC: Total Cholesterol, TG: Triglyceride,