Design and patients
hypertensive, breast cancer
BREAST CANCER
We conducted a single-center, double-blinded, randomized controlled clinical trial among hypertensive patients aged 40–86 years who were scheduled for breast cancer surgery under general anesthesia at Fujian Medical University Union Hospital between September 2021 and June 2022. The inclusion criteria included patients with (1) a body mass index of 18–30 kg/mPatients who provided consent were randomly assigned in a 1:1 ratio to the remimazolam or propofol group. Randomization was computer-generated using Epical 2000 software. Due to the significantly different properties of the two anesthetics, anesthesiologists could not be blinded to the group assignment. However, the allocation was completely concealed from follow-up investigators and participants.