Randomization of patients
malignancy
APPENDIX, THYROID NODULE


Surgery must be performed within 4 months of pre-registration.Quality of life (SF-36, EQ-5D, STAI) questionnaires will be completed by the patient within 1 month before the surgery.Before surgery, the patients will first be pre-registered (included) to check that the thyroid nodule is classified cT1bT2N0 and the FNAB cytology is classified type 5 or 6 according Bethesda (Appendix 2).Randomization (and validation of the inclusion)Randomization (and validation of the inclusion) will then be performed:Before surgery for patients with malignant cytology (Bethesda 6)OR in the operating room, after total thyroidectomy without any particular dissection of paratracheal spaces and after confirmation of malignancy by intra-operative frozen section analysis for patients with suspicious cytology (Bethesda 5).For patients with a nodule Bethesda 5, the randomization form will incude a confirmation of malignancy of the intra-operative frozen section analysis for patients with suspicious cytology Figs. Diagram of the trial designDiagram of randomization