Primary and Secondary Outcomes in Each Diagnostic Group
SE
For the primary clinical outcome (i.e., change in PHQ-9 scores in participants with a PHQ-9 score of ≥10 at baseline), the test for the contrast between the two treatment groups was not significant (mean (SE) difference between treatment groups in change in PHQ-9 score from baseline to 12 months: −0.19 (0.66); PHQ-9 scores in the 366 participants with PHQ-9 ≥10 at baseline (187 in the telephone collaborative care group and 179 in the enhanced usual care group).For a change in GAD-7 in participants with a GAD-7 score of ≥10 at baseline, the test for the contrast between the 2 treatment groups was significant (mean (standard error, SE) difference in change in GAD-7 score from baseline to 12 months: 1.47 (0.67), GAD-7 scores in the 298 participants with GAD-7 ≥10 at baseline (151 in the telephone collaborative care group and 147 in the enhanced usual care group).For the number of weekly drinks in participants with at-risk drinking, the contrast was not significant (ratio of per cent changes in the number of daily drinks from baseline to 12 months: 0.89 (95% CI, 0.63 to 1.27), t(368) = −0.63, Estimates of the effect sizes of the continuous measures were: PHQ-9: Cohen's d = 0.057; 95% CI, −0.29 to 0.404; GAD-7: Cohen's d = 0.38; 95% CI, −0.036 to 0.795; number of weekly drinks: Cohen's d = −0.099; 95% CI, −0.352 to 0.154.Number of weekly drinks in the 176 participants with at-risk drinking at baseline (95 in the telephone collaborative care group and 81 in the enhanced usual care group).