Randomization and allocation sequence
BROWN
162 consenting participants were randomized [1:1 ratio, blocks of 4] into group A, oral dydrogesterone group, and group B, or vaginal cyclogest group. Two equal sets of computer-generated numbers (81 per set) representing each group of the study were generated by an independent statistician. Brown opaque envelopes were numbered consecutively from 1 to 162. Each numbered envelope contained the study group corresponding to its number and was sealed. The envelopes were arranged serially and secured in a locked cupboard at the hospital in Awka and managed by a nurse blinded to the study. Once a woman gave consent for the study and was assigned a serial number, the nurse was reached to open the envelope corresponding to the serial number and announce the group concealed inside for participants allocation.