Abbreviations:
myopic
axial lengthage-related macular degenerationbest-corrected visual acuitychoroidal neovascularizationcycles per degreecontrast sensitivityelectroretinogramhigh myopiamacular pigmentsmacular pigment optical densityper-protocol setvisual acuityThis study was supported by Santen Pharmaceutical Co. Ltd. The sponsor had no control over the interpretation, writing, or publication of the manuscript. The corresponding author had full access to all data in the study and had the final responsibility for the decision to submit for publication.YT is an employee of Santen Pharmaceutical Co., Ltd. The remaining authors have no conflicts of interest to disclose.The datasets generated during and/or analyzed during the current study are publicly available.How to cite this article: Yoshida T, Takagi Y, Igarashi-Yokoi T, Ohno-Matsui K. Efficacy of lutein supplements on macular pigment optical density in highly myopic individuals: A randomized controlled trial. Medicine 2023;102:12(e33280).