Characteristics of gut microbiota composition in patients with PD differs from healthy donors
PD
To figure out whether the change in gut microbiota is associated with clinical improvement in patients with PD, we performed 16S rRNA sequencing for stool samples from donors (3 times during stool donation), as well as patients at baseline and the 4th and 12th weeks after FMT or placebo intervention.Alpha diversity analysis at baseline showed significant differences in PD individuals compared with donors by evaluating the estimate of Faith_Pd or Observed_Otus index (The baseline characteristics of gut microbiota in donors and patients with PD (placebo/FMT group). a-b: α diversity of gut microbiota in different groups according to estimate of Faith_Pd (a) and estimate of Observed_Otus (b) (ns, not significant, ***