Although not certified as a pharmacist, Menier began preparing and selling a variety of powders for medicinal purposes. This aspect of the business grew rapidly and in 1825 he began an expansion through the acquisition of a second production facility on land on the banks of the Marne River at Noisiel, then a small village of less than 200 inhabitants at the outskirts of Paris.
In 1816, Antoine Brutus Menier married Marie-Edmée Virginie Pichon. With her sizeable dowry he was able to go into business and he established the Menier Hardware Company in the Marais district of Paris.