She was one of twenty-two children fathered by the writer Henry Brooke, author of Gustavus Vasa; only she (and perhaps one other sibling) survived childhood.
Charlotte Brooke ( – 1793), born in Rantavan, beside Mullagh in County Cavan, Ireland, was the author of Reliques of Irish Poetry, a pioneering volume of poems collected by her in the Irish language, with facing translations.