On July 24, 1862, the regiment reached Memphis, Tennessee, where they were based. On November 17, 1862, the regiment began an expedition to Vicksburg, Mississippi, and contributed in the campaign until Union Maj. Gen. Ulysses S. Grant was forced to abandon it on account of the capture of his materials at Holly Springs, Mississippi.
On July 24, 1862, the regiment occupied Memphis, Tennessee, serving as its base. In November 1862, the regiment undertook a mission to Vicksburg, Mississippi, and participated in the campaign until Union forces under Maj. Gen. Ulysses S. Grant were forced to withdraw due to the capture of his supplies at Holly Springs, Mississippi.