If Only it Were True is set against the backdrop of San Francisco and tells the story of Lauren Kline, a young, pretty, medical resident, completely devoted to her work in the emergency room of San Francisco Memorial Hospital. She works round-the-clock dealing with patients until she gets into a serious car accident. As a result of the accident, Lauren enters a coma.
She chooses to spend most of her time in her old apartment, where she is discovered by Arthur, the new tenant. Only he can see, hear, or touch her. After some initial disbelief on his part, Arthur agrees to help Lauren.