Her early film roles were usually in films that her actor father was appearing in, such as 'Sei bambine ed il Perseo' ('Perseus and the six children') (1940). Scilla Sclanizza married the prominent Italian puppeteer Otello Sarzi (1922–2001).
Her second marriage was to Mario Verdirosi, also an actor and puppeteer. Scilla Sclanizza died in Turin, Italy in 2006.