Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets.
Glycoprotein VI (GP6), a 58-kilodalton platelet membrane glycoprotein, is essential for collagen-induced platelet activation and aggregation.  Following vessel wall injury and endothelial damage, exposure of the subendothelial matrix to blood flow leads to platelet deposition.