Hence, the name of the song, which Jay-Z is apparently calling his "first song," even though it is the last song on what was to be his last album, as an allusion to what B.I.G. said in the interview.
Therefore, the title of the song stems from Jay-Z's assertion that it is his "initial" work, even though it is the final piece on what was intended to be his last album, and this is an allusion to something B.I.G. said during an interview.