This starts to go against localization theories which would say that the brain is only functioning in specific regions and the brain's ability to perform at any given task is only affected by the overall damage to that area of the brain and damage to an unrelated area shouldn't affect the task. However, equipotentiality and the law of mass action don't mean that there is no localization.
This idea challenges the traditional view of localization theories, which suggest that specific brain regions are dedicated to particular functions. However, equipotentiality and the law of mass action indicate that localized damage can still have a broader impact on cognitive abilities.