These molecules are often involved in the allosteric regulation of enzymes in the control of metabolism. An example of an enzyme activator working in this way is fructose 2,6-bisphosphate, which activates phosphofructokinase 1 and increases the rate of glycolysis in response to the hormone glucagon.
These molecules are typically involved in the allosteric control of enzymes within metabolic pathways. An example is fructose 2,6-bisphosphate, which activates phosphofructokinase 1 and accelerates glycolysis as a result of glucagon stimulation.