Typically, as in most tablet blends, lubricants such as magnesium stearate are added to the blend to reduce the amount of material that may stick to the die wall. Differences may be the use of disintegrating aids, such as crospovidone, and binding agents that aid in mouth feel, such as microcrystalline cellulose. Primarily, ODTs contain some form of sugar such as mannitol, which typically serves as the major diluent of the ODTs, and is also the primary contributor to the smooth and creamy mouth feel of most ODTs.
Typically, lubricants such as magnesium stearate are added to tablet blends to reduce sticking to die walls. Differences may involve disintegrating aids like crospovidone and binding agents that enhance mouth feel, such as microcrystalline cellulose. ODTs usually include sugar, often mannitol, which serves as the primary diluent and contributes to their smooth, creamy texture.