Immunisation of mothers against male-specific minor histocompatibility (H-Y) antigens has a pathogenic role in many cases of secondary recurrent miscarriage, that is, recurrent miscarriage in pregnancies succeeding a previous live birth.
The process of immunising mothers against male-specific minor histocompatibility (H-Y) antigens can lead to pathogenic outcomes in various scenarios of secondary recurrent miscarriage, where miscarriages happen after a successful pregnancy.