The town has the special feature of having changed its name in 1922 from the ancient name of Caccavone to the current name Poggio Sannita, which is derived from the ancient Samnite civilization that once populated the area.
The town's historical significance is highlighted by its name change from Caccavone to Poggio Sannita, a shift reflecting its connection to the ancient Samnite people who previously resided in the region.