CCL20 expression was observed to be dependent on IL-6 amplifier activation, which is dependent on NF-κB and STAT3 activation. This research provides evidence for a critical role for CCL20 in autoimmune pathogenesis of the central nervous system.
CCL20 expression is linked to IL-6 amplifier activation, which is mediated through NF-κB and STAT3 activation. This investigation highlights the importance of CCL20 in the etiology of autoimmune diseases affecting the central nervous system.