When Broadway from 34th Street to Columbus Circle, Sixth Avenue from 34th Street to 59th Street, and Seventh Avenue from Times Square to 59th Street became one-way streets on March 10, 1957, the Broadway-Seventh Avenue route 6's northbound route was shifted to Sixth Avenue between 34th and 59th Streets.
On March 10, 1957, a change occurred when certain streets in Manhattan were designated as one-way. As a result, the northbound route of the Broadway-Seventh Avenue bus line 6 was redirected from its original path to Sixth Avenue between 34th and 59th Streets.