As a central player in the Protein Structure Initiative, their Toronto team contributed to more than a thousand new microbial protein structures over the next decade, developed new crystallization methods, and used structural methods to de-orphanize several nuclear receptors and study ion transport across membranes.
A prominent member of the Protein Structure Initiative's Toronto team played a crucial role in advancing the field over the course of a decade. Their work included the determination of over 1,000 microbial protein structures, the development of innovative crystallization methods, and the application of structural techniques to elucidate orphan nuclear receptors and ion transport across cellular membranes.