Another battalion deployed to Alaska to help build the Alcan Highway and participate in the invasion of Okinawa, and another was posted to Asia to help construct the Burma Road. The remaining components of the 45th Division were sent to Sicily in 1943, where they fought in the campaigns of Naples-Foggia, Rome-Arno, Southern France, Rhineland, and Central Europe.
In addition to deploying a battalion to Alaska for highway construction and participation in the Okinawa invasion, another was stationed in Asia to assist with the Burma Road project. The remaining components of the 45th Division were sent to Sicily in 1943 to fight in various campaigns across Europe and Italy.