Bromo-Seltzer was invented in 1888 by Isaac E. Emerson and produced by the Emerson Drug Company of Baltimore, Maryland. It was sold in the United States in the form of effervescent granules that were mixed with water before ingestion.
Bromo-Seltzer, developed in 1888 by Isaac E. Emerson and manufactured by the Emerson Drug Company of Baltimore, Maryland, was sold in the United States as effervescent granules that were mixed with water prior to consumption.