The Seleucids were unable to retaliate immediately as general Diodotus Tryphon led a rebellion at the capital Antioch in 142 BC. However, by 140 BC Demetrius II Nicator was able to launch a counter-invasion against the Parthians in Mesopotamia.
The Seleucid Empire faced an immediate challenge as general Diodotus Tryphon led a revolt at Antioch in 142 BC. Nevertheless, by 140 BC Demetrius II Nicator was able to launch a retaliatory campaign against the Parthians in Mesopotamia.