This pathway is referred to as retrograde transport. Before the COP I protein can coat vesicles on the Golgi membrane, it must interact with a small GTPase called ARF1 (ADP ribosylation factor). ARF1 that is bound to GDP interacts with the golgi complex membrane.
This pathway is known as retrograde transport. Before the COP I protein can coat vesicles on the Golgi membrane, it must interact with a small GTPase called ARF1 (ADP ribosylation factor). ARF1 bound to GDP interacts with the Golgi complex membrane.