A four-amino acid sequence motif - GYVG, glycine-tyrosine-valine-glycine - conserved in hslU ATPases and located on the inner surface of the assembled pore dramatically accelerates the degradation of some proteins, and is required for the degradation of others.
A specific amino acid sequence motif - GYVG, glycine-tyrosine-valine-glycine - preserved in hslU ATPases and situated on the inner surface of the assembled pore plays a crucial role in speeding up the breakdown of certain proteins, and is essential for their degradation.