SR 745 commences at the signalized intersection between the concurrent US 33 and SR 161 and High Street in Dublin. Running north from there, the two-lane state highway passes through a residential portion of the northwestern Columbus suburb.
Starting at the signaled intersection of US 33 and SR 161 with High Street in Dublin, SR 745 proceeds northwards as a two-lane state road. This route passes through a residential section within the northwest part of Columbus's suburbs.