The order founded the Ecuadorean University of Quito in 1586. Augustinians also entered Argentina via Chile between 1617 and 1626. Political events in these countries prevented the order from prospering and hindered the success of its undertakings.
The founding of the Ecuadorian University of Quito by the order, followed by Augustinian presence in Argentina via Chile, were both impacted by political events that hindered the order's success.