#5 seeds Drake and Clemson fell to #12 seeds Western Kentucky and Villanova while the #4 seeds in that same pod, Vanderbilt and Connecticut, were defeated by #13 seeds Siena and San Diego.
Drake and Clemson, seeded #5 in a particular tournament bracket, lost to #12 seeds Western Kentucky and Villanova, while #4 seeds Vanderbilt and Connecticut lost to #13 seeds Siena and San Diego.