The murine Cr2 gene contains 25 exons; a common first exon is spliced to exon 2 and to exon 9 in transcripts encoding CR1 and CR2, respectively. A transcript with an open reading frame of 4,224 nucleotides encodes the long isoform, CR1; this is predicted to be a protein of 1,408 amino acids that includes 21 short consensus repeats (SCR) of ca. 60 amino acids each, plus transmembrane and cytoplasmic regions.
The murine Cr2 gene has 25 exons, with a common first exon spliced to exon 2 for CR1 and exon 9 for CR2. A transcript encoding the long isoform, CR1, contains an open reading frame of 4,224 nucleotides, resulting in a protein of 1,408 amino acids with 21 short consensus repeats (SCR) of approximately 60 amino acids each, plus transmembrane and cytoplasmic regions.