In general, the IF2 protein plays a crucial role in coordinating many steps of translation initiation, including the binding of mRNA and fMet-tRNA to the start codon, the joining of sub-units, and the activation of GTPase.
IF2 plays a pivotal role in initiating translation by coordinating the binding of mRNA and initiator tRNA to the start codon, as well as the assembly of subunits and activation of GTPase activity.