Unlike NY 380, CR 380 continues south from the hamlet of Kimball Stand, intersecting NY 394 in Falconer and passing through the hamlet of Stillwater to the town of Busti, where it ends at Forest Avenue in the hamlet of Busti  south of Kimball Stand.
Unlike NY 380, CR 380 proceeds south from the hamlet of Kimball Stand, crossing NY 394 in Falconer and passing through the hamlet of Stillwater to the town of Busti, where it concludes at Forest Avenue in the hamlet of Busti south of Kimball Stand.