It is thought to have disappeared some 21,00030,000 years ago, during the late Wisconsin glaciation. But unlike many other megafauna that died out and left no living descendants (at least in the Americas), B. latifrons evolved into the smaller Bison antiquus which made it better adapted to flourish on the open plains.
The species is believed to have become extinct approximately 21,000-30,000 years ago during the late Wisconsin glaciation. Unlike other megafauna that went extinct without leaving behind any living descendants in the Americas, B. latifrons gave rise to the smaller Bison antiquus, which allowed it to adapt and flourish on the open grasslands.