Co-chaperones may also play an important role in misfolding diseases such as cystic fibrosis. An interaction between Hsp90 and its co-chaperone, Aha1, is essential to the proper folding of cystic fibrosis transmembrane conductance regulator (CFTR).
Co-chaperones could play a significant role in misfolding diseases such as cystic fibrosis. The interaction between Hsp90 and its co-chaperone, Aha1, is essential for the proper folding of CFTR.