Her most recent research also includes self-cleaving inteins, which are protein-splicing elements. Because inteins are sometimes found in essential proteins, her group is exploring whether inhibitors of intein splicing could be used as anti-fungal drugs. Belfort has also collaborated with Joachim Frank, a 2017 Nobel Prize winner in chemistry, in studying three-dimensional images of group II introns
Her most recent research also includes self-cleaving inteins, which are protein-joining components. Her team is investigating the potential use of inhibitors of intein splicing as antifungal medications. Furthermore, Belfort has collaborated with Joachim Frank to study group II introns.