In 1954, TISS moved to a permanent campus at Deonar, Mumbai (now known as the Main Campus), from the earlier campuses at Nagpada and then Andheri. In 2001, the Deonar campus was expanded to include the Malti Jal and Jal A. D. Naoroji Campus Annexe, which are now commonly known as the New Campus.
The relocation of TISS in 1954 marked a significant change from its earlier temporary facilities at Nagpada and Andheri to a permanent location at Deonar, Mumbai. In 2001, the Deonar campus was expanded to include an annex, now commonly referred to as the New Campus.