Having begun his career at Cruzeiro and spent time on loan at Botafogo, Jefferson then spent four seasons in the Turkish Süper Lig in service of Trabzonspor and Konyaspor before returning to Botafogo.
Jefferson started his professional career at Cruzeiro and later had a stint on loan at Botafogo. He then played for two Turkish clubs, Trabzonspor and Konyaspor, before returning to Botafogo.