After intravenous administration the onset of analgesia is as little as 1–2 minutes, which may be related to its great lipophilicity. The analgesic and sedative effects of piritramide are believed to be potentiated with phenothiazines and its emetic (nausea/vomiting-inducing) effects are suppressed.
Following intravenous administration, the onset of analgesia occurs within 1–2 minutes. This may be attributed to its high lipophilicity. The analgesic and sedative properties of piritramide are believed to be enhanced by phenothiazines, whereas its emetic effects (causing nausea and vomiting) are suppressed.