Incorporation of an amino alcohol moiety proved crucial to inhibitory activity for many of these agents. This unit is closely related to the one found in the statine, an unusual amino acid that forms part of the pepstatin, a fermentation product that inhibits protease enzymes.
The incorporation of an amino alcohol unit proved essential for the inhibitory activity of many of these agents. This unit is closely related to that found in statine, a unique amino acid that forms part of pepstatin, a fermentation product that inhibits protease enzymes.