The Fas ligands, or cytotoxicity-dependent APO-1-associated proteins, physically associate with APO-1 (also known as the Fas receptor, or CD95), a tumor necrosis factor containing a functional death domain. This association leads to the formation of the DISC, thereby inducing apoptosis.
Fas ligands, cytotoxicity-dependent APO-1-associated proteins, connect with APO-1 (also known as the Fas receptor or CD95), which is part of a tumor necrosis factor containing a functional death domain. This connection leads to the formation of the DISC and initiates apoptosis.