HU can result in bone marrow suppression, and there are warnings that using HU with ddI can increase the risk of pancreatitis. The Health and Human Services (HHS) panel in the US is recommending against the use of Hydroxyurea although some doctors are still using it for various reasons.
Bone marrow suppression is a potential side effect of HU, and caution should be exercised when using HU with ddI to avoid pancreatitis. The Health and Human Services (HHS) panel in the US advises against Hydroxyurea use, although some physicians continue to prescribe it for various reasons.