They played in the Class A Western League through 1954 and in the Triple-A American Association from 1955 to 1959 as an affiliate of their major league namesake, the St. Louis Cardinals.
From 1954 to 1955, they played in the Class A Western League; from 1955 through 1960, they were affiliated with Triple-A teams in the American Association that were part of the major league system of the St. Louis Cardinals.