In intact animals, the mineralocorticoid receptor is "protected" from glucocorticoids by co-localization of an enzyme, corticosteroid 11-beta-dehydrogenase isozyme 2 (a.k.a.
In intact animals, the mineralocorticoid receptor is shielded from glucocorticoids by the presence of an enzyme called corticosteroid 11-beta-dehydrogenase isozyme 2.