AD is triggered by either noxious or non-noxious stimuli, resulting in sympathetic stimulation and hyperactivity. The most common causes include bladder or bowel over-distension from urinary retention and fecal compaction, pressure sores, extreme temperatures, fractures, undetected painful stimuli (such as a pebble in a shoe), sexual activity, and extreme spinal cord pain. The noxious stimuli activates a sympathetic surge that transmits through intact peripheral nerves, resulting in systemic vasoconstriction below the level of the spinal cord lesion.
AD is triggered by either harmful or non-harmful stimuli, leading to sympathetic activation and hyperactivity. Common causes include bladder or bowel over-distension due to urinary retention and fecal compaction, pressure sores, extreme temperatures, fractures, undetected painful stimuli (such as a pebble in the shoe), sexual activity, and severe spinal cord pain. Harmful stimuli trigger a sympathetic response that spreads through intact peripheral nerves, causing systemic vasoconstriction below the spinal cord lesion.