Similarly to the other members of the GDNF family of ligands, persephin uses a receptor that consists of the tyrosine kinase signaling component Ret and a unit of glycosylphosphatidylinsitol (GPI)-anchored receptor (GFRα).
Like other members of the GDNF family of ligands, persephin employs a receptor comprising the tyrosine kinase signaling component Ret and a GPI-anchored receptor unit (GFRα).