In the west of the valley, along the Mitis River on the Matapedia Road, was the first parish to be canonically erected in 1868: Sainte-Angèle-de-Merici. Inhabited since 1870 and canonically erected in 1873, the Saint-Moïse parish is the oldest in the interior of the valley. At its eastern extremity lies the Saint-Alexis-de-Matapédia parish, which was founded in 1870 by twelve Acadians.
In the western part of the valley, along the Mitis River on the Matapedia Road, was the first parish to be canonically established in 1868: Sainte-Angèle-de-Merici. Occupied since 1870 and canonically established in 1873, the Saint-Moïse parish is the oldest within the valley interior. At its eastern extremity lies the Saint-Alexis-de-Matapédia parish, which was founded in 1870 by twelve Acadians.