The series is set in Los Angeles, California, and follows the stories of a Federal Bureau of Investigation (FBI) team and a mathematics professor, focusing on relationships between FBI Special Agent in Charge Don Eppes (Rob Morrow), his brother Professor Charlie Eppes (David Krumholtz) and their father, Alan Eppes (Judd Hirsch), and on the brothers' efforts to fight crime.
The series is set in Los Angeles, California, and centers on an FBI team and a mathematics professor, highlighting the relationships between FBI Special Agent in Charge Don Eppes (Rob Morrow), his brother Professor Charlie Eppes (David Krumholtz) and their father, Alan Eppes (Judd Hirsch). The brothers' efforts to combat crime are central to the story.