The Keystone Shortway, now Interstate 80, runs diagonally across the Nittany Valley on a west to east line, from Curtin Gap east of Milesburg, Pennsylvania, to a natural gap in  Mount Nittany and then via a deep rock cut along the Long Run stream.
Interstate 80, formerly known as the Keystone Shortway, cuts across the Nittany Valley on a west to east trajectory, beginning at Curtin Gap near Milesburg, Pennsylvania, through a natural gap in Mount Nittany and then by means of a deep rock cut along the Long Run stream.