On 23 January 1735, Lord Rialton was created Baron Godolphin of Helston in Cornwall, with special remainder, in default of his own issue, to the heirs male of his deceased uncle, Dr Henry Godolphin, dean of St. Paul's. During the king's absence from Britain in 1723, 1725 and 1727, Godolphin acted as one of the lords justices of the United Kingdom. Finally, as Lord Privy Seal, he was in office from 14 May 1735 to 25 April 1740.
On January 23, 1735, Lord Rialton was created Baron Godolphin of Helston in Cornwall with a special provision for his uncle's heirs if he had no children. During the King's absence from Britain in 1723, 1725 and 1727, Godolphin served as one of the Lords Justices of the United Kingdom. He held the position of Lord Privy Seal from May 14, 1735 to April 25, 1740.