KLF/Sps are a family of transcription factors that contain three carboxyl-terminal (C-terminal) C2H2-type zinc finger structural motifs that bind to the GC-rich regions in DNA and regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. The C-terminal end binds to the promoter and enhancer regions of a gene.
KLF/Sps are transcription factors with specific zinc finger structures that interact with DNA sequences in GC-rich regions. These interactions regulate cellular functions like proliferation, differentiation, and apoptosis, affecting various tissue types during development and homeostasis. The C-terminal end binds to gene promoter and enhancer regions.