He was the chairman of the Department of Biostatistics and Applied Mathematics at the University of Texas M. D. Anderson Cancer Center from 1999-2010, where he played a role in the use of Bayesian methods to develop innovative, adaptive clinical trials.
He held the position of chairman of the Department of Biostatistics and Applied Mathematics at the University of Texas M. D. Anderson Cancer Center from 1999 to 2010, where he contributed to the application of Bayesian methods in developing innovative, adaptive clinical trials.