Replication occurs in the chloroplasts of plant cells. Key features of replication include no helper virus required and no proteins are encoded for. Unlike the other family of viroids, Pospiviroidae, Avsunviroidae are thought to replicate via a symmetrical rolling mechanism.
Replication in plant cells' chloroplasts lacks the need for helper viruses and does not involve protein production. This contrasts with another viroid family, Pospiviroidae, which is believed to replicate through a symmetrical rolling mechanism.