The resulting deregulation of cell signaling leads to blocking of phagocytosis and reduction in the ability of neutrophils to kill bacteria. It also inhibits maturation of dendritic cells and their migration to the lymph nodes.
Deregulation of cell signaling results in a blockage of phagocytosis, a reduction in neutrophils' ability to kill bacteria, inhibition of dendritic cell maturation and their migration to lymph nodes.