Moreover, CD133+ melanoma cells are immunogenic and can be used as an antimelanoma vaccination. In mice the vaccination with CD133+ melanoma cells mediated strong anti-tumor activity that resulted in the eradication of parental melanoma cells.
Additionally, CD133+ melanoma cells are immunogenic and can serve as a vaccine against melanoma. When injected into mice, these cells triggered powerful anti-tumor effects, resulting in the eradication of the original melanoma cells.