At the height of the 2001 EDSA Revolution, Reyes withdrew his support for Estrada, which led to the installation of Vice President Gloria Macapagal Arroyo as president, under whom he then served as Cabinet Secretary until 2010.
At the pinnacle of the 2001 EDSA Revolution, Reyes pulled out his endorsement for Estrada, which led to the installation of Vice President Gloria Macapagal Arroyo as head of state, and he then worked under her administration as Cabinet Secretary until 2010.