Mediated by adenylate cyclase-activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase-activating polypeptide 1 not only is a hypophysiotropic hormone (i.e. a substance that induces activity in the hypophysis), but also functions as a neurotransmitter and neuromodulator.
This polypeptide, mediated by adenylate cyclase-activating polypeptide 1 receptors, triggers adenylate cyclase activity and raises cAMP levels in target cells. Adenylate cyclase-activating polypeptide 1 is a hypophysiotropic hormone (a substance that stimulates the pituitary gland) and also serves as a neurotransmitter and neuromodulator.