The two highways parallel the city line to SR 197 (Malvern Avenue), then pass over I-195 with no direct access. US 33 and US 250 intersect SR 161 (Boulevard) northwest of the Science Museum of Virginia, in the former Broad Street railroad station. US 33 and US 250 split just east of the Siegel Center, home of the Virginia Commonwealth University Rams basketball teams, with US 250 continuing on Broad Street, while US 33 turns north onto Hancock Street.
The two highways run parallel to the city boundary, crossing over I-195 without direct access. US 33 and US 250 intersect SR 161 (Boulevard) near the Science Museum of Virginia, in the former Broad Street railroad station.  US 33 and US 250 split just east of the Siegel Center, home to the Virginia Commonwealth University Rams basketball team, with US 250 continuing on Broad Street while US 33 turns north onto Hancock Street.