On 7 January 1944 the district was created under the named Oktyabr District (ноҳияи Октябр) was created in the Qurghonteppa Oblast.
In late 1944, the region of Qurghonteppa Oblast gained a new administrative division, known as the Oktyabr District (ноҳияи Октябр), which was established on 7 January 1944.