In 1899 he became principal of Italy’s only rabbinical seminary, the Collegio Rabbinico Italiano when it transferred from Rome to Florence. Margulies was a powerful spiritual force in Italy and trained many of its religious leaders. He founded and edited Rivista Israelitica, the learned journal published by the Seminary.
He held the position of principal at Italy’s sole Jewish theological school, the Collegio Rabbinico Italiano, when it relocated from Rome to Florence in 1899. Margulies was a prominent spiritual figure in Italy and trained many of its religious leaders. He established and edited Rivista Israelitica, a scholarly journal published by the institution.