MetaCyc includes mini reviews for pathways and enzymes that provide background information as well as relevant literature references. It also provides extensive data on individual enzymes, describing their subunit structure, cofactors, activators and inhibitors, substrate specificity, and, when available, kinetic constants.
MetaCyc features brief evaluations of metabolic routes and enzymes, providing supplementary context as well as relevant scholarly references. It also provides detailed information on each enzyme, including its structural makeup, collaborating molecules, enhancers and inhibitors, preferred substrates, and, if available, rate constants.