Acrydite-modified oligonucleotides can react with nucleophiles such as thiols (Michael addition chemistry), this forms the basis of the ez-rays chemistry which was used for microarrays. More importantly, Acrydite-modified oligonucleotides can be incorporated, stoichiometrically, into hydrogels such as polyacrylamide, using standard free radical polymerization chemistry, where the double bond in the Acrydite group reacts with other activated double bond containing compounds such as acrylamide.
Acrydite-modified oligonucleotides react with nucleophiles like thiols (Michael addition) to form the basis of ez-rays chemistry used for microarrays.  They can also be incorporated into hydrogels, such as polyacrylamide, using free radical polymerization chemistry where the Acrydite group's double bond reacts with other activated double bonds.