Typically, the inhaled bacilli implant in the distal airspaces of the lower part of the upper lobe or the upper part of the lower lobe, usually close to the pleura. As sensitization develops, a 1 to 1.5 cm area of gray-white inflammation with consolidation emerges, known as the Ghon focus. In most cases, the center of this focus undergoes caseous necrosis.
Inhaled bacteria typically settle in the distal airspaces of the lower upper lobe or upper lower lobe, near the pleura. As sensitization develops, a 1 to 1.5 cm area of gray-white inflammation with consolidation forms, known as the Ghon focus. In most cases, the center of this focus undergoes caseous necrosis.