eIF1 binds near the ribosomal P-site, while eIF1A binds near the A-site, in a manner similar to the structurally and functionally related bacterial counterparts IF3 and IF1, respectively.
The initiation factor eIF1 is positioned near the ribosomal P-site, while eIF1A is located close to the A-site. This arrangement mirrors that of their bacterial homologs IF3 and IF1, which exhibit analogous structures and functions.