Chromosome combing is also used to study DNA replication, a highly regulated process that is reliant on a specific program of temporal and spatial distribution of activation of origins of replication. Each origin occupies a distinct genetic locus and must fire only once per cell cycle.
Chromosome combing is also employed to study DNA replication, a tightly controlled procedure that relies on a precise schedule of temporal and spatial distribution of activation of origins of replication. Each origin occupies a unique genetic locus and must fire only once per cell cycle.