TCP has slightly different binding properties to PCP, with more affinity for the NMDA receptors, but less affinity for the sigma receptors. Because of its high affinity for the PCP site of the NMDA receptor complex, the 3H radiolabelled form of TCP is widely used in research into NMDA receptors.
TCP binds differently to PCP, with greater affinity for NMDA receptors and lesser for sigma receptors. Due to its strong binding at the PCP site of the NMDA receptor complex, the 3H-labeled TCP is frequently used in studies on NMDA receptors.