Further west it enters Moreland Township and passes the village of Opp, before entering Muncy Creek Township, where it flows into Muncy Creek just west of the village of Clarkstown. Other streams feeding Little Muncy Creek include Marsh Run, Beaver Run, Laurel Run, Big Run, German Run, and Little Indian Run.
In a more western direction, Little Muncy Creek enters Moreland Township and passes through the village of Opp before flowing into Muncy Creek Township. It then empties into Muncy Creek near Clarkstown Village. Streams contributing to Little Muncy Creek include Marsh Run, Beaver Run, Laurel Run, Big Run, German Run, and Little Indian Run.