Lepère was studying architecture in Antwerp, when she was persuaded by her friends Dries van Noten and Olivier Theyskens to try modelling. She first appeared on the runways in Paris in 2000 and is currently signed with IMG Models.
Lepère's background in architecture influenced her decision to model, encouraged by friends Dries van Noten and Olivier Theyskens. Her modeling career started on Paris runways in 2000, and she's now a part of IMG Models.