This chemokine is chemotactic for monocytes and can activate these cells in the presence of an inflammatory mediator called prostaglandin-E2 (PGE2). It is also a potent chemoattractant and activator of dendritic cells, is implicated in homing of these cells, and can stimulate the migration of activated NK cells.
A specific chemokine that draws monocytes towards it and can activate them when combined with PGE2. Additionally, this chemokine serves as a powerful magnet for dendritic cells, plays a role in their navigation, and can prompt the migration of activated NK cells.