Like many strong acids, hexafluorophosphoric acid is handled only in solution. It exothermically reacts with water to  produce oxonium hexafluorophosphate () and hydrofluoric acid.
Hexafluorophosphoric acid, similar to other strong acids, must be handled exclusively as a solution. When it reacts with water, it produces oxonium hexafluorophosphate () and hydrofluoric acid.