For example, the (R)- and (S)-enantiomers of 1-phenylethanol react with (S)-Mosher acid chloride to yield (R,S)- and (S,S)-diastereomers, respectively, that are distinguishable in NMR.
This example demonstrates how the reaction between (R)- and (S)-enantiomers of 1-phenylethanol with (S)-Mosher acid chloride yields diastereomeric compounds that can be differentiated using NMR spectroscopy, illustrating the significance of stereochemistry in understanding chemical reactions.