In 1566, while holding a council with his senior retainers at Kōzenji Temple, Iechika was shot to death by Endō Matajirō and Yoshijirō, two brothers who had received orders from Ukita Naoie.
In 1566, during a gathering of high-ranking officials at Kōzenji Temple, Iechika's life was cut short by Endō Matajirō and Yoshijirō, the sons of Ukita Naoie who had been given explicit instructions to eliminate him.