Food allergy and variable IgE response to food substances has been observed in some patients which implies role of hypersensitive response in pathogenesis. Many patients indeed have history of other atopic conditions like eczema, asthma, etc.
The observation of food allergy and variable IgE response to food substances suggests that hypersensitivity reactions contribute to the pathogenesis. Moreover, many patients with this condition also have a history of other atopic conditions such as eczema and asthma.