Al-Khalifa was appointed as ambassador to Italy in 1966. In March 1968, he was transferred to become ambassador to the United Kingdom. On 25 May 1969, when Gaafar Nimeiry seized power, Al-Khalifa was bluntly informed about his end of service and stripped of his diplomatic passport.
Al-Khalifa served as an ambassador in Italy from 1966 to 1968, then moved to the United Kingdom. In May 1969, when Gaafar Nimeiry took control, Al-Khalifa was dismissed and his diplomatic credentials revoked.