"Neuron specific" mouse Thy-1 promoter has been used to drive "brain specific" forced expression of proteins e.g. mutated Amyloid precursor protein(APP) as transgenic animal models of Alzheimer's disease. Thy-1 expression in the brain is developmentally regulated.
"Neuron-specific" mouse Thy-1 promoter has been used to induce "brain-specific" forced expression of proteins, e.g., mutated Amyloid precursor protein (APP) as transgenic animal models of Alzheimer's disease. Thy-1 expression in the brain is developmentally regulated.