Mutations in SLC25A15 cause ornithine translocase deficiency. Ornithine translocase deficiency belongs to a class of metabolic disorders referred to as urea cycle disorders. The urea cycle is a sequence of reactions that occurs in liver cells.
Mutations in SLC25A15 lead to a type of metabolic disorder that affects the functioning of the urea cycle, which is a series of chemical reactions taking place within liver cells.