Kindler originally created Sanctuary as an eight-part web series, but later it was adapted for television. The series is set in the fictional city of Old City and follows centuries-old scientist Helen Magnus and her team: daughter Ashley; protégé Will Zimmerman; computer tech and Lycan Henry Foss; and an aptly named "Bigfoot"; and con artist Kate Freelander.
Kindler initially planned Sanctuary as an eight-part web series but eventually adapted it for television. The show is set in the imaginary city of Old City and revolves around Helen Magnus, a centuries-old scientist, and her team: daughter Ashley; protégé Will Zimmerman; computer tech and Lycan Henry Foss; "Bigfoot"; and con artist Kate Freelander.