The hospital was founded in 1900 as the Southampton Union Infirmary in Shirley Warren, Southampton, to replace hospital beds previously provided at the workhouse infirmary in St Mary's, Southampton. The Royal South Hampshire Hospital was the voluntary hospital, founded in 1835 in the city.
The hospital was inaugurated in 1900 as the Southampton Union Infirmary in Shirley Warren, Southampton, to take over beds previously provided at the workhouse infirmary in St Mary's, Southampton. The Royal South Hampshire Hospital was a voluntary institution established in 1835 within the city.