State Route 522 was designated in 1947. The original routing of the state route followed the majority of today's routing, running from its junction with what was then a two-lane alignment of U.S. Route 52 (now known as Gallia Street) on the southern fringe of Wheelersburg to its present eastern terminus at what was then known as State Route 75 (now State Route 93).
State Route 522 was established in 1947. The original route followed a majority of today's route, running from its junction with what was then a two-lane alignment of U.S. Route 52 (now known as Gallia Street) on the southern edge of Wheelersburg to its present eastern terminus at what was then known as State Route 75 (now State Route 93).