It runs in a southwest-to-northeast direction, from the main gate of Naval Base Guam in the southwestern village of Santa Rita in a northeasterly direction to the main gate of Andersen Air Force Base in the village of Yigo. It passes through Guam's capital, Hagåtña, as well as intersecting other territorial highways. The highway runs through tropical forest, urbanized commercial areas, and residential neighborhoods.
This highway follows a path that starts at the main gate of Naval Base Guam in Santa Rita, then moves northeast to Andersen Air Force Base in Yigo. The route passes through the capital city of Hagåtña and intersects other roads within the territory. It traverses diverse environments including forests, commercial areas, and residential neighborhoods.