As with many other companies manufacturing computers based on the S-100 bus, it soon found itself struggling to compete against the rising domination of the IBM Personal Computer and its many clones in the mid-1980s. By 1986, InterSystems had folded.
Similar to numerous computer manufacturers utilizing the S-100 bus, InterSystems struggled to compete with the rise of IBM's Personal Computer and its imitators during the mid-1980s. The company folded by 1986.