Jaenisch’s first breakthrough occurred in 1974, when he and Beatrice Mintz showed that foreign DNA could be integrated into the DNA of early mouse embryos They injected retrovirus DNA into early mouse embryos and showed that leukemia DNA sequences had integrated into the mouse genome and also into that of its offspring.
Jaenisch’s initial success came in 1974, when he and Beatrice Mintz demonstrated that foreign DNA could be incorporated into the genetic material of early mouse embryos They introduced retrovirus DNA into early mouse embryos and showed that leukemia DNA sequences had been integrated into both the mouse genome and its offspring.