It is a heterodimeric cytokine that is encoded by two distinct genes, Epstein-Barr virus-induced gene 3 (EBI3) and IL-27p28. IL-27 is expressed by antigen presenting cells and interacts with a specific cell-surface receptor complex known as IL-27 receptor (IL-27R).
It is a heterodimeric cytokine derived from two distinct genes, Epstein-Barr virus-induced gene 3 (EBI3) and IL-27p28. Interleukin-27 (IL-27) is expressed by antigen-presenting cells and engages with a specific cell-surface receptor complex called the interleukin-27 receptor (IL-27R).