However, it can occur in pseudoxanthoma elasticum and idiopathic arterial calcification of infancy as a pathological condition, as well. Its clinical significance and cause are not well understood and its relationship to atherosclerosis and other forms of vascular calcification are the subject of disagreement.
This condition can also be found in pseudoxanthoma elasticum and idiopathic arterial calcification of infancy as a pathological state. Its clinical relevance and underlying factors are unclear, and there is controversy surrounding its link to atherosclerosis and other types of vascular hardening.