The FDA has deemed PGPR to be generally recognized as safe for human consumption, and the Joint FAO/WHO Expert Committee on Food Additives (JECFA) has also deemed it safe. Both of these organisations set the acceptable daily intake at 7.5 milligrams per kilogram of body weight.
The regulatory agencies, specifically the FDA and the Joint FAO/WHO Expert Committee on Food Additives (JECFA), have determined that PGPR is safe for human consumption, with a recommended daily intake limit of 7.5 milligrams per kilogram of body weight.