The Neolithic archaeological remains found in the village are proof that the region around Pano Lefkara has been inhabited uninterruptedly for many centuries. The first historical testimony of the existence of Pano Lefkara with its present-day name is found in the testament of Saint Neophytos, born in 1134 in the village of Kato Drys near Pano Lefkara, when Cyprus was part of the Byzantine Empire.
The archaeological findings in the village demonstrate uninterrupted habitation for many centuries. The earliest written record of Pano Lefkara's existence, with its current name, is found in the testament of Saint Neophytos, born in 1134 in Kato Drys, during Cyprus' time under the Byzantine Empire.