The Sisters of St. Joseph added two dormitory wings to the building and moved their novitiate and Saint Joseph College of Florida, which was then a sisters' formation college to the property. In 1957, the novitiate was moved to the end of Britt Road and the college was converted into a regular liberal arts college. The college closed in May 1972 and its campus including Tuckahoe was sold to Florida Institute of Technology for its Jensen Beach Campus.
The Sisters of St. Joseph expanded their structure by adding dormitory sections and relocated their novitiate and Saint Joseph College of Florida, a college for sisters' education, to the property. In 1957, the novitiate was repositioned to Britt Road's conclusion, and the college became an independent liberal arts institution. The college ceased operations in May 1972, and its campus, including Tuckahoe, was sold to Florida Institute of Technology for its Jensen Beach Campus.