The pharmacologic effects of β adrenergic agonist drugs, such as orciprenaline, are at least in part attributable to stimulation through β adrenergic receptors of intracellular adenylyl cyclase, the enzyme which catalyzes the conversion of ATP to cAMP. Increased cAMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from many cells, especially from mast cells.
The effects of β-adrenergic agonists like orciprenaline on the body are linked to their stimulation of adenylyl cyclase, an enzyme that converts ATP to cAMP. This leads to increased cAMP levels, which in turn cause relaxation of bronchial smooth muscle and inhibition of the release of mediators responsible for immediate hypersensitivity from cells, particularly mast cells.