Once chemical activity is factored into the correct form of the equation, a dimensionless value is obtained. For the binding of receptor and ligand molecules in solution, the molar Gibbs free energy ΔG, or the binding affinity is related to the dissociation constant Kd via
Once chemical activity is incorporated into the correct form of the equation, a dimensionless value is obtained. For the binding of receptor and ligand molecules in solution, the molar Gibbs free energy ΔG, or the binding affinity, is related to the dissociation constant Kd via...