Peña made the Major League roster out of spring training for the first time in his career in 2007. He made his season debut on April 3 against the Colorado Rockies, tossing two scoreless innings of relief. He earned his first win on April 18, pitching a perfect inning of relief.
In 2007, Peña was called up to the Major League for the first time in his career and made his debut against the Colorado Rockies on April 3, where he pitched two scoreless innings. He later earned his first win on April 18 by pitching a perfect inning of relief.