The sequence of human GM-CSF was first identified in 1985 and soon three recominbant human GM-CSFs were produced, one in bacteria, one in mammalian cells, and one in yeast; Immunex developed GM-CSF manufactured in yeast into Leukine.
In 1985, the sequence of human GM-CSF was identified, resulting in the production of three recombinant forms: one in bacteria, one in mammalian cells, and one in yeast. Immunex transformed GM-CSF produced in yeast into a product known as Leukine.