These receptors were originally identified by their ability to bind N-formyl peptides such as N-formylmethionine produced by the degradation of either bacterial or host cells. Hence formyl peptide receptors are involved in mediating immune cell response to infection.
These receptors were initially recognized by their capacity to adhere to N-formyl peptides like N-formylmethionine, which is generated from bacterial or host cell degradation. Consequently, formyl peptide receptors are engaged in facilitating immune cell responses against infections.