Originally, SR 68 extended from Micco Bluff Road in Okeechobee County west of Basinger near the Kissimmee River, following US 98-SR 700, Northeast 160th Street (present County Road 68), Parrott Avenue (US 441-SR 15), Northeast 224th Street (present County Road 68), and the aptly named Orange Avenue (present County Road 68) to SR 713 as it cuts across the wetlands and the orange groves of central Florida to Fort Pierce.
SR 68 began at Micco Bluff Road in Okeechobee County west of Basinger near the Kissimmee River, then followed US 98-SR 700, Northeast 160th Street (present County Road 68), Parrott Avenue (US 441-SR 15), Northeast 224th Street (present County Road 68), and Orange Avenue (present County Road 68) before reaching SR 713 as it crossed the wetlands and orange groves of central Florida, ultimately arriving in Fort Pierce.