The 106th continued serving with the District of North Alabama, part of the Department of the Cumberland, until February 1865, when it was transferred to the Defenses of Nashville and the Northwestern Railroad in the same department. For this period the regiment continued garrisoning Pulaski and guarding railroads.
The 106th Regiment continued its service in the District of North Alabama, part of the Department of the Cumberland, until February 1865 when it was moved to the Defenses of Nashville and the Northwestern Railroad within the same department. During this time, the regiment remained stationed at Pulaski and provided security for the railroads.