An important and exploitable property of aurophilic interactions relevant to their supramolecular chemistry is that while both inter- and intramolecular interactions are possible, intermolecular aurophilic linkages are comparatively weak and easily broken by solvation; most complexes that exhibit intramolecular aurophilic interactions retain such moieties in solution.
Aurophilic interactions, a significant aspect of supramolecular chemistry, are characterized by their ability to form both intra- and intermolecular bonds. However, the strength of intermolecular aurophilic linkages is relatively weak and easily broken by solvation. Most complexes that exhibit these interactions retain them within the molecule itself in solution.