Other instances of SWI/SNF acting as a tumor suppressor comes from the heterozygous deletion of BAF47 or alteration of BAF47. These instances result in cases of chronic and acute CML and in rarer cases, Hodgkin's lymphoma, respectively. To prove that BAF47, also known as SMARCB1, acts as a tumor suppressor, experiments resulting in the formation of rhabdoid tumors in mice were conducted via total knockout of BAF47.
The role of SWI/SNF as a tumor suppressor is also evident in cases where there is a loss or mutation of BAF47. This can lead to chronic and acute CML, as well as rare instances of Hodgkin's lymphoma. To confirm that SMARCB1 (also known as BAF47) acts as a tumor suppressor, studies involving the complete elimination of BAF47 in mice resulted in the formation of rhabdoid tumors.