Noradrenaline is released from the neurons, and acts on adrenergic receptors. Noradrenaline is often released steadily so that it can prepare the supporting glial cells for calibrated responses. Despite containing a relatively small number of neurons, when activated, the noradrenaline system plays major roles in the brain including involvement in suppression of the neuroinflammatory response, stimulation of neuronal plasticity through LTP, regulation of glutamate uptake by astrocytes and LTD, and consolidation of memory.
In the context of neural function, noradrenaline is released from nerve cells and binds to adrenergic receptors. This sustained release allows glial cells to respond more precisely. Although the brain contains a relatively small number of neurons, when stimulated, the noradrenaline system plays vital roles in regulating various functions, including suppressing inflammation, stimulating neuronal adaptability through long-term potentiation, managing glutamate levels by astrocytes, and consolidating memories.