When Pope Paul IV imposed the rule of cloister on the Angelicals, whom their foundress had destined for works of active charity, particularly the care of the sick and orphans, in 1557 she instituted another community, also at Milan, for whom she built a house between the Roman and the Tosa gate, known as the Collegio della Guastalla.
When Pope Paul IV imposed a rule of seclusion on the Angelicals, whom their founder had intended for works of active charity, particularly the care of the sick and orphans, in 1557 she established another community at Milan, also known as the Collegio della Guastalla.