Born in Athens, Tziortziopoulos started his career at third division side Keratsini in the 1997/98 season and his performances caught the eye of Olympiacos, who signed him in the summer of 1998. Six months later he went on loan to Iraklis to gain experience and stayed until January 2000, when he returned to Olympiacos to make his debut.
Tziortziopoulos's career trajectory involved a move from Keratsini to Olympiacos and then a loan spell at Iraklis before returning to Olympiacos for his professional debut.