For the bulk of its length, it runs parallel to Interstate 64 and approximately  north of it. Most of the route is two-lane undivided highway, with undivided multi-lane segments in the city of Princeton around the junction of U.S. Route 41, and through the city of Huntingburg as well as near English.
This roadway runs parallel to Interstate 64, generally located north of it.  The majority of the route consists of two-lane undivided highways, with specific segments being divided multi-lane roads in Princeton, Huntingburg, and near English.