All members of the VEGF family stimulate cellular responses by binding to tyrosine kinase receptors (the VEGFRs) on the cell surface, causing them to dimerize and become activated through transphosphorylation.
The VEGF family triggers cellular responses by binding to tyrosine kinase receptors (VEGFRs) on the cell surface, causing them to form dimers and become activated through transphosphorylation. A single VEGF molecule can activate thousands of receptor molecules.