Ctgf-null mice also show defects in angiogenesis, with impaired interaction between endothelial cells and pericytes and collagen IV deficiency in the endothelial basement membrane.
Mice lacking Ctgf display defects in angiogenesis, characterized by impaired communication between endothelial cells and pericytes and a lack of collagen IV in the endothelial basement membrane, highlighting the importance of this process.