In the late 1960s, the then-Rochester–Monroe County Airport expanded its primary runway southward across a tract of land that included part of NY 252A's routing. As a result, NY 252A was moved onto a new alignment that circumvented the runway to the south.
In the late 1960s, the Rochester–Monroe County Airport extended its main runway towards the south, intersecting part of NY 252A's route. As a consequence, NY 252A was redirected onto a new alignment that bypassed the runway to the south.