She began her acting career in 1996 when she was in the movie Set it Off. In 1997, she played evil step-sister Minerva in the Disney made-for-television movie Cinderella. Desselle-Reid starred in many films, including Madea's Big Happy Family, and guest starred in Family Matters.
In 1996, she began her acting career with a role in the film "Set it Off".  The following year, she played the evil step-sister Minerva in the Disney made-for-television movie "Cinderella". Desselle-Reid appeared in numerous films, including "Madea's Big Happy Family", and guest starred on "Family Matters".