Following the discovery of its activity as a potent negative allosteric modulator of mGluR5, fenobam has been re-investigated for many applications, with its profile of combined antidepressant, anxiolytic, analgesic and anti-addictive effects potentially useful given the common co-morbidity of these symptoms.
Following the discovery of its potent inhibitory action on mGluR5, fenobam has been re-examined for numerous applications, with its profile of combined antidepressant, anxiolytic, analgesic, and anti-addictive effects potentially beneficial given the common comorbidity of these symptoms.