The diagnosis of anogenital papillary hidradenoma lesions, while often suggested based on their clinical presentations, must be differentiated from a wide range of other similarly presenting anogenital lesions such as hemorrhoidal disease, anorectal abscesses, virus-related wart-like lesions, sebaceous cysts, mucous cysts, lipomas, neurofibromas, metastatic carcinomas with papillary histopathology, syringocystoadenocarcinoma papilliferum (i.e.
The diagnosis of anogenital papillary hidradenoma lesions, which is frequently supported by clinical observations, should be distinguished from a variety of other similar-looking conditions such as hemorrhoidal diseases, anal abscesses, virus-related warts, sebaceous cysts, mucous cysts, lipomas, neurofibromas, metastatic carcinomas with papillary histology, and syringocystoadenocarcinoma papilliferum (i.e.