The enzyme PBGD contains a four-amino-acid insertion which is present in all Streptomyces species and Kitasatospora setae, but not any other Actinomycetota.
The presence of a specific four-amino-acid insertion in the PBGD enzyme is notable for being present in all Streptomyces and Kitasatospora species, but not found in any other members of the Actinomycetota group.