By displaying that the decay of G-CSF mRNA, in the presence of actinomycin D, was slower in SB203580-treated cells. SB203580 increased the stability of G-CSF mRNA.
The finding that the breakdown of G-CSF mRNA, when exposed to actinomycin D, occurred more slowly in cells treated with SB203580 implies that SB203580 increases mRNA durability.