The focus of his scientific activities was on the characterization of the development of localized fungal infections of the skin and related mucosal surfaces. He concentrated on secreted aspartic proteases of Candida albicans as virulence factors and toll-like receptors as relevant mediators of the inflammatory host response. It was his prime concern to develop active pharmaceutical ingredients for the treatment and prevention of fungal infections reflecting the increased understanding of pathogenesis.
His scientific pursuits centered on characterizing the development of localized fungal infections of the skin and related mucosal surfaces. He focused on secreted aspartic proteases of Candida albicans as virulence factors and toll-like receptors as key mediators of the inflammatory host response. His primary objective was to develop active pharmaceutical ingredients for treating and preventing fungal infections, based on a growing understanding of pathogenesis.