Chinese Ligusticum root contains alkaloids that have been shown in studies to inhibit TNF-alpha production and TNF-alpha-mediated NF-kappaB activation. One study conducted in Japan showed the active compounds found in Ligusticum sinense have both anti-inflammatory and pain-reducing effects, exerting its anti-inflammatory benefits in the early and the late stages of processes in the inflammatory pathology.
Chinese Ligusticum root contains alkaloids that studies have shown inhibit TNF-alpha production and NF-kappaB activation through TNF-alpha. A Japanese study revealed that the active compounds in Ligusticum sinense possess both anti-inflammatory and pain-relieving properties, which exert their benefits at the beginning and end of inflammatory processes.