Common types of bioconjugation reactions on proteins are coupling of lysine, cysteine, and tyrosine amino acid residues, as well as modification of tryptophan residues and of the N- and C- terminus.
Bioconjugation reactions commonly target protein molecules at specific sites, including lysine, cysteine, and tyrosine amino acids, as well as the N- and C-termini, and sometimes tryptophan residues.