The diocese is bounded on the north by the Archdiocese of Mérida-Badajoz, on the east by the Archdiocese of Seville and Diocese of Cádiz, on the south by the Atlantic Ocean, and on the west by the Diocese of Faro, in the Portuguese Algarve, of which it is separated by the Guadiana river.
The diocese is situated within a specific geographical location with its boundaries defined by the Archdiocese of Mérida-Badajoz to the north, the Archdiocese of Seville and Diocese of Cádiz to the east, the Atlantic Ocean to the south, and the Diocese of Faro in Portugal's Algarve region to the west.