Tyndall lies on the Sierra Crest, which in this region forms the boundary between the John Muir Wilderness and the Inyo National Forest on the east, and Sequoia National Park on the west; and the boundary between Inyo and Tulare counties.
Located on the Sierra Crest ridge, Tyndall is situated at the intersection of several protected areas, including the John Muir Wilderness, Inyo National Forest, and Sequoia National Park, as well as the border between Inyo and Tulare counties.