The DNA-binding core consists of the WHD, which leads to a tower domain. A coiled-coil region leads to a C-terminal domain that forms the main dimer interface for this crystal state (often termed the C-gate).
The DNA-binding core consists of the WHD, leading to a structural formation known as a tower domain. A coiled-coil section ultimately leads to a C-terminal domain that functions as the primary interface between dimers in this specific crystalline state (referred to as the C-gate).