After crossing over Otsquago Creek, NY 163 intersects with Clinton Avenue, where the route turns west along the creek. At the junction with Garfield Street, the name changes to Douglass Street, which runs alongside the Otsquago through a residential section of Fort Plain. Just after the junction with Honey Hill Road, the route crosses into the town of Minden, changing names to Cherry Valley Road.
After crossing Otsquago Creek on NY 163, it links with Clinton Avenue, which then proceeds west along the creek. At Garfield Street, the road is renamed Douglass Street and continues alongside the Otsquago through a residential area of Fort Plain. Just after Honey Hill Road, the route enters Minden, where it becomes Cherry Valley Road.