A Bucket of Blood was the first of a trio of collaborations between Corman and Griffith in the comedy genre, which include The Little Shop of Horrors (which was shot on the same sets as A Bucket of Blood) and Creature from the Haunted Sea. Corman had made no previous attempt at the genre, although past and future Corman productions in other genres incorporated comedic elements.
A Bucket of Blood was the starting point for a series of three films that Corman made with Griffith in the comedy genre, which also includes The Little Shop of Horrors (filmed on the same sets as A Bucket of Blood) and Creature from the Haunted Sea. Although Corman had not attempted this genre before, his other productions featured comedic elements.