Mackaill rose to leading-lady status in the drama The Man Who Came Back (1924), opposite rugged matinee idol George O'Brien. In 1924, she also starred in the western film The Mine with the Iron Door, shot on location outside of Tucson, Arizona.
Mackaill's rise to fame began when she starred in the drama The Man Who Came Back (1924) opposite the charismatic George O'Brien. In 1924, she also appeared in the western film The Mine with the Iron Door, shot in the desert landscapes around Tucson, Arizona.