Autosomal dominant hypophosphatemic rickets (ADHR) is a rare hereditary disease in which excessive loss of phosphate in the urine leads to poorly formed bones (rickets), bone pain, and tooth abscesses. ADHR is caused by a mutation in the fibroblast growth factor 23 (FGF23).
A rare genetic condition known as autosomal dominant hypophosphatemic rickets (ADHR) occurs when there is an excessive loss of phosphate in the urine, leading to poorly developed bones (rickets), bone discomfort, and tooth infections. This disorder is caused by a mutation in the fibroblast growth factor 23 (FGF23).