Jenckes ran unopposed in the Democratic primary, but Noble J. Johnson, her Republican challenger, narrowly defeated her in the general election. Jenckes, who suggested her loss was the result of ballot tampering, was among the seventy Democrats in the U.S. House who were defeated for re-election that year.
Jenckes dominated the Democratic primary without an opponent, but Noble J. Johnson, her Republican challenger, emerged victorious in the general election by a narrow margin. Jenckes blamed her defeat on alleged electoral malfeasance, and she was one of seventy Democrats in the U.S. House who lost their seats that year.