When in the bloodstream, 96,6% of the substance are bound to blood plasma proteins. Its main metabolite is silodosin glucuronide, which inhibits the α1A receptor with 1/8 of the affinity of the parent substance.
When circulating in the bloodstream, 96.6% of this substance is bound to plasma proteins in the circulatory system. Its primary metabolite is silodosin glucuronide, which blocks the α1A receptor with reduced efficacy compared to the parent compound.