Similar to Phenylalanine-associated pathways, the reaction molecular basis is critical in mammalian metabolism, as evidenced by the observed liver enzyme activity in FAH deficiency during hereditary tyrosinemia type 1. In humans, this enzyme is mainly expressed in the liver.
The underlying mechanism for reactions similar to Phenylalanine-associated pathways plays a vital role in mammalian metabolism, as illustrated by the elevated liver enzyme activity in FAH deficiency cases of hereditary tyrosinemia type 1. In humans, this enzyme predominantly resides in the liver.