It is used in the Van Leusen reaction which is used to convert aldehydes to nitriles or in the preparation of oxazoles and imidazoles. The versatility of TosMIC  in organic synthesis has been documented. It is a fairly strong carbon acid, with an estimated pKa of 14 (compared to 29 for methyl tolyl sulfone), the isocyano group acting as an electron acceptor of strength comparable to an ester group.
TosMIC is a strong carbon acid, similar to methyl tolyl sulfone, which has an estimated pKa of 14 (compared to 29). The isocyano group acts as an electron acceptor comparable to an ester group.