Most class III adenylyl cyclases are transmembrane proteins with 12 transmembrane segments. The protein is organized with 6 transmembrane segments, then the C1 cytoplasmic domain, then another 6 membrane segments, and then a second cytoplasmic domain called C2. The important parts for function are the N-terminus and the C1 and C2 regions.
Most class III adenylyl cyclases are transmembrane proteins with 12 transmembrane segments. The protein is structured with 6 transmembrane segments, followed by the C1 cytoplasmic domain, then another 6 membrane segments, and then a second cytoplasmic domain called C2. The crucial parts for function are the N-terminus and the C1 and C2 regions.