The incumbent, Dem-NPL Senator Quentin Burdick, sought and received re-election to his second term, defeating Republican candidate Thomas S. Kleppe, who later became the United States Secretary of the Interior.
The incumbent Dem-NPL Senator Quentin Burdick secured re-election to his second term by defeating Republican candidate Thomas S. Kleppe, who later held a high-ranking position within the U.S. government.