The town would be a stronghold of Swabian and Angevin nobility until the fourteenth century, when a series of great houses would rule Loreto and the surrounding countryside up to the abolition of feudalism: among others, the d'Aquino, the d'Avalos, the Caracciolo, as well as Margaret Habsburg, and Alessandro de' Medici.
The town was under the control of powerful families from the Swabian and Angevin lineages until the fourteenth century, when feudalism ended: among them were the d'Aquino, the d'Avalos, the Caracciolo, Margaret Habsburg, and Alessandro de' Medici.