This mutation alters a cysteine involved in a disulfide bond in the extracellular N-terminus of the protein. This extracellular region is similar to the cell adhesion molecule contactin and other cell adhesion molecules.
A change in this protein's structure, specifically involving a cysteine within its extracellular N-terminal region, disrupts a disulfide bond. This region resembles cell adhesion molecules like contactin and others.