As a member of the BCL2 protein family, BAK1 functions as a pro-apoptotic regulator involved in a wide variety of cellular activities. In healthy mammalian cells, BAK1 localizes primarily to the MOM, but remains in an inactive form until stimulated by apoptotic signaling.
BAK1, being part of the BCL2 protein family, functions as a pro-apoptotic controller involved in various cellular activities. In healthy mammalian cells, BAK1 primarily resides at the mitochondria outer membrane (MOM), but remains dormant until activated by apoptotic signals.