Mutations in alpha-synuclein are associated with early-onset familial Parkinson's disease and the protein aggregates abnormally in Parkinson's disease, Lewy body disease, and other neurodegenerative diseases.
Changes to alpha-synuclein are associated with early-onset familial Parkinson's disease, and the protein accumulates abnormally in conditions such as Parkinson's disease, Lewy body disease, and other neurodegenerative illnesses.