In 562, when the warlord Zhou Di (), who controlled parts of modern Jiangxi, rebelled, Wu was made the governor of Jiang Province (江州, roughly modern Jiujiang), to command the army against Zhou. However, the strict Wu was unable to get his subordinate generals to obey his orders, and Emperor Wen subsequently sent his brother Chen Xu the Prince of Ancheng to replace Wu.
In 562, when the warlord Zhou Di rose up in revolt, Wu was appointed governor of Jiang Province (jiang state) to lead the army against Zhou. However, the strict Wu failed to get his subordinates to follow his orders, and Emperor Wen subsequently sent his brother Chen Xu, the Prince of Ancheng, to replace Wu.