The methyl phosphase capping enzyme MEPCE puts a methyl group on the gamma phosphate of the first nucleotide of the 7SK RNA and the La related protein LARP7 binds to the 3' end of 7SK.
MEPCE, the methyl phosphite capping enzyme, attaches a methyl group to the gamma phosphate of the first nucleotide in the 7SK RNA. Simultaneously, LARP7, the La-related protein, binds to the 3' end of 7SK.