It is known, however, that plants and animals have analogous mechanism for small RNA-guided heterochromatin formation, and it is believed that the mechanisms described above for S. pombe are highly conserved and play some role in heterochromatin formation in mammals as well.
It is acknowledged that despite differences, plants and animals share a common mechanism for small RNA-guided heterochromatin formation, and it is inferred that the processes described earlier for S. pombe are remarkably preserved and likely play a role in mammalian heterochromatin formation as well.