N-terminal- elongated innexins can act as a plug to manipulate hemichannel closure and provide a mechanism connecting the effect of hemichannel closure directly to apoptotic signal transduction from the intracellular to the extracellular compartment.
N-terminal elongated innexins can act as a plug to regulate hemichannel closure, providing a pathway for connecting hemichannel closure to apoptotic signal transduction from the intracellular to extracellular environment.