Further extensions opened to McVeytown on December 24, Mount Union on April 1, 1850, Huntingdon on June 10, and Duncansville (west of Hollidaysburg) on September 16, 1850, taking it to a connection with the Allegheny Portage Railroad on the east side of the Allegheny Ridge. On the other side of the ridge, the main line opened from Conemaugh (on the Portage Railroad east of Johnstown) west to Lockport on August 25, 1851.
Further expansions were made to McVeytown on December 24, Mount Union on April 1, 1850, Huntingdon on June 10, and Duncansville (west of Hollidaysburg) on September 16, 1850. This connected it with the Allegheny Portage Railroad on the east side of the Allegheny Ridge. On the other side of the ridge, the main line opened from Conemaugh (on the Portage Railroad east of Johnstown) west to Lockport on August 25, 1851.