There are some requirements that must be accomplished to gain short circuit stimulation. One of them is to have Phe-X-Gly-Leu-Met-NH2 sequence at C-terminal where X could be Val or Ile. The other requirement is to have 2 or 1 proline residue at N-terminal.
To trigger short circuit stimulation, specific sequences are needed. One of these involves a Phe-X-Gly-Leu-Met-NH2 sequence at the C-terminal, where X can be either Val or Ile. Another requirement is that there should be 2 or 1 proline residue at the N-terminus.