RANTES, or Regulated upon Activation Normal T-cell Expressed and Secreted, is a cytokine that is an inflammatory mediator chemotactic for a variety of inflammatory immune cells such as granulocytes and macrophages. However, much work remains to be done in fully characterizing the signaling of ICAM-1. The relationship between ICAM-1 and ICAM-2 signaling environments has not been established beyond mere correlation; a study linking ICAM signaling to actual modulation of an inflammatory environment in vivo has yet to be conducted.
RANTES, or Regulated upon Activation Normal T-cell Expressed and Secreted, is a cytokine that plays a role as an inflammatory mediator and attracts immune cells like granulocytes and macrophages. However, further research is needed to fully understand the signaling mechanisms of ICAM-1. The relationship between ICAM-1 and ICAM-2 signaling environments has not been extensively studied beyond correlation; a study linking ICAM signaling to actual modulation of an inflammatory environment in vivo has yet to be conducted.