FCE 28260 has been found to inhibit rat and human 5α-reductase with half-maximal inhibitory concentrations (IC50) of 15 and 16 nM, respectively, while finasteride had values of 30 and 52 nM.
FCE 28260 has been found to suppress the activity of rat and human 5α-reductase enzymes with half-maximal inhibitory concentrations (IC50) of 15 and 16 nM, respectively. Finasteride showed lower efficacy in inhibiting these enzymes, with IC50 values of 30 and 52 nM.