These sarcomas often involve lymphoid tissues, but in a number of cases the tumor has been found in the liver, bile duct, pancreas, thyroid, nasopharynx, palatum, submucosa of the stomach or the duodenum. In a number of chronic inflammatory conditions, cells producing CXCL13 chemokine and carrying such FDCs markers as VCAM-1 and CD21, have been observed at quite unexpected sites, including synovial tissue of patients with rheumatoid arthritis (RA), salivary glands of patients with Sjögren’s syndrome, and the skin of patients with pseudo B cells lymphoma.
Sarcomas can occur in lymphoid tissues but also in various organs like the liver, bile duct, pancreas, thyroid, nasopharynx, palatum, submucosa of the stomach or duodenum.  In chronic inflammatory conditions, cells producing CXCL13 chemokine and carrying markers such as VCAM-1 and CD21 have been found at unexpected locations, including synovial tissue in rheumatoid arthritis patients, salivary glands in Sjögren’s syndrome patients, and skin in pseudo B cell lymphoma patients.