The inheritance conflict was continued in the broader contest of the Thirty Years' War, in which Hesse-Kassel sided with the Protestant estates and Hesse-Darmstadt sided with the Habsburg emperor. The Hesse-Homburg and Hesse-Rotenburg estates seceded from the opponents in 1622 and 1627.
The inheritance conflict was prolonged within the larger struggle of the Thirty Years' War, where Hesse-Kassel collaborated with the Protestant nobles and Hesse-Darmstadt allied itself with the Habsburg ruler. The Hesse-Homburg and Hesse-Rotenburg estates deserted their opponents in 1622 and 1627.