While previously cases universally required heart transplantation, recent studies show that two-thirds of patients can survive past one year with high doses of immunosuppressants such as prednisone and cyclosporine. The transplanted heart has a high chance of disease recurrence. Compared to lymphocytic (presumed viral) myocarditis, giant cell myocarditis is much more severe with much more rapid progression.
While previously cases uniformly necessitated heart transplantation, recent studies indicate that two-thirds of patients can endure past one year with high doses of immunosuppressive agents such as prednisone and cyclosporine. The transplanted heart has a considerable likelihood of disease recurrence. In contrast to lymphocytic (presumed viral) myocarditis, giant cell myocarditis is much more severe with much faster progression.