Typically, by the age of six months, failure to thrive and developmental delays are obvious signs of this disorder. Some physical signs, such as abnormal skeletal development, coarse facial features (e.g. bulging scaphocephalic head, flat nose), and restricted joint movement, may be present at birth.
Typically, by six months old, a child with this disorder will show signs of failure to thrive and developmental delays. Some physical signs, such as abnormal bone development, coarse facial features (e.g., bulging scaphocephalic head, flat nose), and restricted joint movement, may be present at birth.