It runs from State Road 50 in Ocoee, to State Road 15, the frontage roads of State Road 408, in Orlando. After the western terminus of SR 526, State Road 50, it becomes W Washington St. Between US 441 and the western terminus, it is known as County Road 526, and locally known as Old Winter Garden Road.
State Road 50 starts at Ocoee and continues to State Road 15, the frontage roads of State Road 408 in Orlando. After SR 526's western endpoint, it turns into W Washington St. Between US 441 and its western terminus, it is called County Road 526 or Old Winter Garden Road.