The route begins at a T-intersection with SR 309 in Washington Township. It heads a short distance east and immediately intersects SR 61. SR 288 curves to the east-northeast just past this junction, bounded by farmland on the south side and woods on the north side.
This route starts at an intersection with SR 309 in a rural area of Washington Township. It heads eastward for a brief period before crossing over SR 61. The road then turns to go northeast past that point, situated between fields and trees.