PolyQ studies often use a variety of animal models because there is such a clearly defined trigger – repeat expansion. Extensive research has been done using the models of nematode (C. elegans), and fruit fly (Drosophila), mice, and non-human primates.
PolyQ studies frequently utilize a variety of animal models due to the clear mechanism of expansion. Extensive research has been conducted using nematode (C. elegans), fruit fly (Drosophila), mice, and non-human primate models, all of which exhibit similar expansion processes.