FGFR2IIIc is found in mesenchyme, which includes craniofacial bone and for this reason the mutations of this gene and isoform are associated with craniosynostosis.
Within mesenchyme, which comprises craniofacial bone, FGFR2IIIc can be found. Given this location, mutations in the gene and its variant form are likely to be linked with craniosynostosis.