About 5–10% of asthmatics have aspirin hypersensitivity, but dietary salicylates have been shown not to contribute to this. The reactions in AERD (Samter's triad) are due to inhibition of the COX-1 enzyme by aspirin, as well as other NSAIDs that are not salicylates.
Around 5–10% of asthmatics experience aspirin hypersensitivity, but dietary salicylates haven't been linked to this condition. The reactions in AERD (Samter's triad) are due to the COX-1 enzyme being inhibited by aspirin and other non-salicylate NSAIDs.