The fT>MIC (%) was increased by 11% when the administration frequency was increased from every four hours to every three hours. This implied that increasing the frequency might yield similar results in humans. The study also found no significant difference between the effectiveness of carbapenems and cefoxitin and suggested that cefoxitin can be used as an alternative treatment for CTX-M producing E. coli to carbapenems such as imipenem and ertapenem.
The fT>MIC (%) was elevated by 11% when the administration frequency was increased from every four hours to every three hours. This suggested that increasing the frequency might produce comparable outcomes in humans. The study also discovered no significant variation between the efficacy of carbapenems and cefoxitin, implying that cefoxitin can be used as an alternative treatment for CTX-M producing E. coli compared to carbapenems such as imipenem and ertapenem.