On March 16 of 1542, Heredia departed for Antioquia to annex the territory to Cartagena. There Heredia was taken prisoner himself  by Sebastián de Belalcázar and sent to Panamá to stand trial for his attempts to seize control of Antioquia.
On March 16, 1542, Heredia departed for Antioquia to annex the territory to Cartagena. He was captured by Sebastián de Belalcázar and sent to Panama for trial on charges of attempting to seize control of Antioquia.