It is still considered a homolog of frizzled because it contains a Cysteine Rich Domain (CRD), and because of its intracellular C-terminus which is crucial for signaling. The CRD is highly conserved in diverse proteins, such as receptor tyrosine kinases and functions as a ligand binding domain.
It continues to be considered a homolog of frizzled due to the presence of a Cysteine Rich Domain (CRD) and an intracellular C-terminus crucial for signaling. The CRD is highly conserved in various proteins, such as receptor tyrosine kinases, and acts as a ligand binding domain.