NaV1.5 is found primarily in cardiac muscle, where it mediates the fast influx of Na+-ions (INa) across the cell membrane, resulting in the fast depolarization phase of the cardiac action potential. As such, it plays a major role in impulse propagation through the heart.
NaV1.5 is a protein found primarily in cardiac muscle cells that plays a key role in the fast depolarization phase of the cardiac action potential, which is essential for impulse propagation through the heart.