Upham also had an influential relationship with Harriet Beecher Stowe while she resided in Brunswick. The Stowe and Upham families were close; Stowe described them as  “delightful... such a perfect sweetness and quietude in all its movements...
While residing in Brunswick, Upham had a significant influence on Harriet Beecher Stowe. The Stowe and Upham families were close; Stowe referred to them as "delightful... such a perfect sweetness and peace in all their movements..."