In Powellville, MD 354 intersects the western terminus of MD 374 (Burbage Crossing Road) at an acute angle and the eastern terminus of MD 350 (Mount Hermon Road) at a right angle before crossing Adkins Mill Pond. After passing through more farmland, the state highway enters the town of Willards and intersects U.S. Route 50 (US 50, Ocean Gateway).
MD 354 in Powellville, Maryland, meets MD 374 (Burbage Crossing Road) at a sharp intersection and MD 350 (Mount Hermon Road) at a right angle before crossing Adkins Mill Pond. The highway then passes through more rural areas before entering the town of Willards and intersecting US Route 50 (US 50, Ocean Gateway).