In the aftermath of the collapse of the Ottoman Empire and the political situation in the new state of Turkey, where the seat of the Patriarchate was located in Deir al-Za'faran for about 10 centuries, Mor Aphrem was forced to relocate the Patriarchate to Homs in Syria.
In the aftermath of the Ottoman Empire's collapse and the unstable politics in early 20th-century Turkey, where the Patriarchate had been based in Deir al-Za'faran for nearly a century, Mor Aphrem was forced to move the Patriarchate from its historic site to Homs, Syria.