pFPP has been found in vitro to act mainly as a 5-HT1A receptor agonist, with some additional affinity for the 5-HT2A and 5-HT2C receptors.
In vitro studies have revealed that pFPP primarily acts on the 5-HT1A receptor, but also exhibits some cross-reactivity with the 5-HT2A and 5-HT2C receptors in controlled laboratory environments.