Mikindani is situated in the Swahili Coast, a cultural area spanning from Mozambique to Somalia. It is situated 250 kilometres south of Kilwa, a significant Swahili city, at the southernmost point of that coast.
Mikindani's geographical position is described as being within the Swahili Coast, which extends from Mozambique to Somalia. It lies approximately 250 kilometers south of Kilwa, a prominent Swahili city, at the southernmost edge of this coastal region.