There he discovered that acetylcholinesterase is present at high concentrations in many different types of excitable nerve and muscle fibres and in brain tissue - lending support for Otto Loewi and Henry Dale's then novel proposal that acetylcholine functions in the transmission of impulses from nerves across junctions to other nerves or to muscles.
At this location, he discovered significant amounts of acetylcholinesterase in different types of excitable nerve and muscle fibers as well as brain tissue. This observation supports Otto Loewi and Henry Dale's then novel hypothesis that acetylcholine is involved in the transmission of impulses from nerves to other nerves or muscles.