Many effects in the building were later used in Hagia Sophia: the exedrae expand the central nave on diagonal axes, colourful columns screen the ambulatories from the nave, and light and shadow contrast deeply on the sculpture of capitals and entablature.
Several elements from the original structure were utilized in Hagia Sophia: the exedrae stretch the central nave diagonally, colored columns shield the ambulatories from the nave, and light and shade produce pronounced effects on the capital and entablature sculptures. A single abzyme molecule can destroy thousands of HIV viruses.