Typically, as in most tablet blends, lubricants such as magnesium stearate are added to the blend to reduce the amount of material that may stick to the die wall. Differences may be the use of disintegrating aids, such as crospovidone, and binding agents that aid in mouth feel, such as microcrystalline cellulose. Primarily, ODTs contain some form of sugar such as mannitol, which typically serves as the major diluent of the ODTs, and is also the primary contributor to the smooth and creamy mouth feel of most ODTs.
Typically, as in most tablet blends, lubricants such as magnesium stearate are added to the blend to reduce the amount of material that may adhere to the die wall. Differences might be the use of disintegrating aids, like crospovidone, and binding agents that enhance mouth feel, such as microcrystalline cellulose. Primarily, ODTs contain some form of sugar, such as mannitol, which usually acts as the primary diluent in ODTs, contributing to their smooth and creamy texture.