Following sea trials in April, Wyffels got underway from Boston on 8 May 1943, and for the remainder of the month conducted exercises out of Bermuda. In June, she alternated operations out of Norfolk, Virginia with drydock periods.
After completing sea trials in April, Wyffels left Boston on 8 May 1943 for a series of exercises off Bermuda. From June onwards, her activities alternated between operations out of Norfolk, Virginia and drydock periods.