At that time Mayaca appears to have been allied with the Mocama, or Agua Salada Timucua chief Saturiwa  against the Agua Dulce (Freshwater) Timucua. In 1567 the Mayaca joined with the Saturiwa and the Potano, another Timucua people, against the Agua Dulce, which was defeated with Spanish aid.
During that period, it appears that Mayaca formed an alliance with the Mocama or Agua Salada Timucua leader Saturiwa  to counter the Agua Dulce (Freshwater) Timucua. In 1567, Mayaca teamed up with Saturiwa and the Potano against the Agua Dulce, ultimately emerging victorious thanks to Spanish support.