Immunohistochemical staining is often helpful in this regard, endocervical adenocarcinomas are typically CEA and p16 positive and estrogen receptor, progesterone receptor and vimentin negative.
Immunohistochemistry is often helpful in identifying these tumors, with endocervical adenocarcinomas typically showing positivity for CEA and p16 while being negative for estrogen receptors, progesterone receptors, and vimentin.