The DNA-binding core consists of the WHD, which leads to a tower domain. A coiled-coil region leads to a C-terminal domain that forms the main dimer interface for this crystal state (often termed the C-gate).
The DNA-binding core is composed of the WHD, which eventually gives rise to a structural element known as a tower. The coiled-coil region then leads to a C-terminal domain that serves as the primary connection point for dimers in this particular crystal configuration (often referred to as the C-gate).