After PR 280, PR 391 becomes a two-lane gravel road through the uninhabited portions of northern Manitoba. The route runs northwest and west for various points until reaching the area of Mooswuchi Lake.
After PR 280 is put into effect, PR 391 changes into a two-lane gravel road that passes through the unpopulated regions of northern Manitoba. The route extends in a northwestern and westerly direction to multiple destinations before arriving at the Mooswuchi Lake region.