Located in the district are the separately listed Patee House, a hotel that is a U.S. National Historic Landmark, and Jesse James House. Other notable buildings include the Morey Piro House (1910), Charles E. Herycele House (1903), R. L. McDonald Manufacturing Co. Warehouse (1899), Mrs. Pemetia Cornish Duplex (c. 1886), Fred Wenz Store Building (1903), Fire Station #5 (1939), German Salems Church (later, Bne Jacob Synagogue, c. 1880, 1927), and Matthew Ziebold House (1895).
The district houses the Patee House, a U.S. National Historic Landmark hotel, as well as the Jesse James House. Other notable buildings include the Morey Piro House from 1910, the Charles E. Herycele House from 1903, the R. L. McDonald Manufacturing Co. Warehouse from 1899, the Mrs. Pemetia Cornish Duplex from around 1886, the Fred Wenz Store Building from 1903, Fire Station #5 from 1939, German Salems Church (later Bne Jacob Synagogue), and the Matthew Ziebold House from 1895.