A new dynasty called Konbaung led by King Alaungpaya rose in Upper Burma to challenge the southern forces, and went on to conquer all of Upper Burma by January 1754. After Hanthawaddy's second invasion of Upper Burma failed in May 1754, the kingdom's leadership in self-defeating measures killed off the Toungoo royal family, and persecuted ethnic Burmans in the south, both of which only strengthened Alaungpaya's hand.
The rise of Konbaung dynasty under King Alaungpaya marked a significant turning point in Upper Burma's history. The kingdom's actions following Hanthawaddy's second invasion further solidified Alaungpaya's power and led to the demise of the Toungoo royal family, ultimately strengthening his position.