Later, it was shown that the binding pattern of the swainsonine molecule resembles that of the Michaelis complex of mannose and only the protonated, charge positive swainsonine molecule binds similarly to the substrate in its transition state.
Later, it was discovered that the binding pattern of the swainsonine molecule resembles that of the Michaelis complex of mannose; only the protonated, positively charged swainsonine molecule binds similarly to the substrate in its transition state.