These autoantibodies are present in nearly 95% of patients with primary biliary cholangitis, an autoimmune disease of the liver. In primary biliary cholangitis, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed.
These autoantibodies are found in nearly 95% of patients with primary biliary cholangitis, an autoimmune liver disease. In primary biliary cholangitis, activated T lymphocytes assault and annihilate epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed.