Lev Nessov suggested the age of the tooth was Early Devonian, belonging to the Dniester Series, of which is rich in Porolepis teeth, but this could not be completely confirmed at the time. Olshevsky (2000) noted that the holotype tooth of Macrodontophion is similar to those of a crocodile or a plesiosaur.
Lev Nessov believed the tooth's age was Early Devonian, part of the Dniester Series, which contains many Porolepis teeth. Olshevsky (2000) indicated that Macrodontophion's holotype tooth resembled those from crocodiles or plesiosaurs.