The August 1, 1943, Journal of The American Dental Association referenced Dean as acknowledging the difficulty of identifying an optimal concentration with the following quote, "The same amount of fluorine that causes a mild toxic reaction in one individual may cause a severe reaction in another.
The August 1, 1943, Journal of The American Dental Association referenced Dean as acknowledging the challenge of pinpointing an ideal fluoride concentration with the following quote, "The same amount of fluorine that causes a mild toxic response in one person may cause a severe reaction in another.