HU can result in bone marrow suppression, and there are warnings that using HU with ddI can increase the risk of pancreatitis. The Health and Human Services (HHS) panel in the US is recommending against the use of Hydroxyurea although some doctors are still using it for various reasons.
Bone marrow suppression can occur due to HU use, and there are warnings that pairing HU with ddI might elevate the risk of pancreatitis. Despite this, the Health and Human Services (HHS) panel in the US discourages Hydroxyurea usage, yet some doctors still prescribe it for various reasons.