A year later more than 300 had died in a measles epidemic. Many of the Guaycura were still semi-nomadic and the efforts of the Franciscans to make of them toilers of the soil on mission lands was a failure as many ran away.
A year later, over 300 people died from a measles outbreak. Many of the Guaycura remained semi-nomadic, and the Franciscans' attempts to convert them into farmers on mission lands were unsuccessful as many fled.