Rome finished the 2010–11 season with an NHL career-high 56 games with a goal and four assists. In the 2011 playoffs, he scored his first NHL post-season goal against Antti Niemi of the San Jose Sharks in Game 2 of the third round – a 7–3 win. The following game, he was injured off a boarding hit from Sharks forward Jamie McGinn.
Rome reached a career-best 56 games in the 2010–11 season, scoring a goal and providing four assists. In the 2011 playoffs, he scored his first postseason goal against Antti Niemi of the San Jose Sharks in Game 2 of the third round – a 7–3 victory. The following game, he was injured after being hit by Jamie McGinn of the Sharks.