These molecules are often involved in the allosteric regulation of enzymes in the control of metabolism. An example of an enzyme activator working in this way is fructose 2,6-bisphosphate, which activates phosphofructokinase 1 and increases the rate of glycolysis in response to the hormone glucagon.
Certain molecules play a crucial role in the allosteric modulation of enzymes during metabolic processes. For instance, fructose 2,6-bisphosphate acts as an enzyme activator that increases phosphofructokinase 1 activity and enhances glycolysis when stimulated by glucagon.