Unlike most of the viral structural proteins which are glycosylated in the endoplasmic reticulum (ER) and Golgi apparatus by host-encoded glycosyltransferases, PBCV-1 glycosylates its major capsid protein independently by encoding most of the enzymes necessary for constructing the complex oligosaccharides, which then attach to the major capsid protein of PBCV-1 to form the glycoprotein.
Unlike most viral structural proteins, which are glycosylated in the endoplasmic reticulum (ER) and Golgi apparatus by host-encoded glycosyltransferases, PBCV-1 glycosylates its major capsid protein independently using enzymes encoded for constructing complex oligosaccharides that attach to the major capsid protein of PBCV-1.