After intravenous administration the onset of analgesia is as little as 1–2 minutes, which may be related to its great lipophilicity. The analgesic and sedative effects of piritramide are believed to be potentiated with phenothiazines and its emetic (nausea/vomiting-inducing) effects are suppressed.
After intravenous administration, the onset of analgesia is as little as 1–2 minutes, which might be due to its high lipophilicity. The analgesic and sedative effects of piritramide are thought to be intensified by phenothiazines, while its emetic (nausea/vomiting-inducing) effects are mitigated.