Food allergy and variable IgE response to food substances has been observed in some patients which implies role of hypersensitive response in pathogenesis. Many patients indeed have history of other atopic conditions like eczema, asthma, etc.
Some individuals exhibit an allergic reaction to certain foods, which is accompanied by an irregular IgE response. This phenomenon implies that hypersensitivity plays a part in the disease's development. Many of these patients also have a history of other atopic disorders like eczema and asthma.