Tir, and over 25 other bacterial proteins are secreted from attaching and effacing E. coli directly into the cytoplasm of intestinal epithelial cells by a Type three secretion system.
Secretion of Tir and more than 25 bacterial proteins occurs directly into the cytoplasm of intestinal epithelial cells by attaching and effacing E. coli through a Type three secretion system, which is responsible for this process.