In the central nervous system, Apo-E is mainly produced by astrocytes and transports cholesterol to neurons via APOE receptors, which are members of the low density lipoprotein receptor gene family. Apo-E is the principal cholesterol carrier in the brain.
In the context of the central nervous system, Apo-E is primarily produced by astrocytes and facilitates the transport of cholesterol to neurons through APOE receptors, which are part of the low-density lipoprotein receptor gene family. This molecule plays a crucial role in transporting cholesterol within the brain.