She portrayed Afia Khan's maternal aunt Shameem on EastEnders in 2011. In 2011, Indrani appeared as Brenda Kiely in the Sky1 comedy drama series The Café.
Indrani's acting role involved playing a relative of Afia Khan, namely her aunt Shameem, on the TV show EastEnders in 2011. She also portrayed a character named Brenda Kiely in the Sky1 sitcom The Café that year.