The most common cause of enlargement of the submental lymph nodes are infections (including viral infections (mononucleosis, Epstein-Barr virus infection, and cytomegaloviral infections), toxoplasmosis, and dental infections (e.g.
The primary reason for submental lymph node swelling is infection (including viral infections such as mononucleosis, Epstein-Barr virus, cytomegalovirus, toxoplasmosis, and dental infections).