Upham was the cousin of George Baxter Upham and Jabez Upham. Upham was later a historian of Salem and the Salem Witch Trials of 1692 when he lived there.
Upham was a family member of George Baxter Upham and Jabez Upham. He later specialized in documenting historical events in Salem, particularly those related to the 1692 witch trials when he lived there.