Sensitization, a form of reverse tolerance, develops rapidly to the positive, euphoric effects of alcohol, but not to the physical effects, such as sedation and respiratory depression, which diminish with prolonged use. This sensitization does not occur, however, with administration of benzodiazepines or neuroactive steroids, which only exhibit weakening of effect with repeated use.
Sensitization, a form of reverse tolerance, quickly adapts to the pleasurable effects of alcohol but not to its physical impacts like sedation and respiratory depression, which weaken with continued use. This sensitization does not happen, though, when benzodiazepines or neuroactive steroids are administered, as they only show a reduction in effect over time.