Paraneoplastic syndromes are typical among middle-aged to older people, and they most commonly occur with cancers of the lung, breast, ovaries or lymphatic system (a lymphoma). Sometimes, the symptoms of paraneoplastic syndromes show before the diagnosis of a malignancy, which has been hypothesized to relate to the disease pathogenesis.
Paraneoplastic syndromes are most commonly seen in middle-aged and older adults, often related to cancers of the lung, breast, ovaries or lymphatic system (lymphoma). In some instances, symptoms of paraneoplastic syndromes may appear before a malignancy is diagnosed, which has led to speculation about their connection to disease development.