As most of Srey Santhor district is low lying and parallels the Mekong, Srey Santhor is subject to annual flooding when the Mekong rises. However, in 2000 90% of the land area in the district was flooded and 95% of the annual rice crop was completely destroyed.
Srey Santhor district, which is predominantly flat and follows the Mekong River, experiences flooding annually when the river rises. In 2000, 90% of the land area in the district was inundated, and 95% of the annual rice crop was destroyed.