Thrombembolic MCAO is achieved either by injecting clots that were formed in vitro or by endovascular instillation of thrombin for in situ clotting . The thrombembolic model is closest to the pathophysiology of human cardioembolic stroke.
Thromboembolic MCAO can be induced by injecting clots created in vitro or by using thrombin to induce clotting at the site of the vessel. The thromboembolic model is most closely aligned with the pathophysiology of human cardioembolic stroke.