However, this passage can become difficult for ageing red blood cells due to their less flexible membranes and therefore they get stuck in the cords and they will be subsequently phagocytosed by the red pulp macrophages.
Nevertheless, this pathway becomes problematic for older red blood cells because of their less pliable membranes; as a result, they become lodged within the cords and are eventually taken up by the red pulp macrophages.