In 2006, the Penguins went 6–1 in the Gateway Conference to win the league title outright. For the seventh time in school history, the Penguins advanced to the NCAA semifinals, defeating foes James Madison University and Illinois State University before falling to top-ranked Appalachian State University.
The Penguins dominated their opponents in 2006, finishing with an impressive 6–1 record in the Gateway Conference to secure the league championship. This marked the seventh time in school history that the Penguins had advanced to the NCAA semifinals, where they defeated James Madison University and Illinois State University before being edged by Appalachian State University.