CCL20 expression was observed to be dependent on IL-6 amplifier activation, which is dependent on NF-κB and STAT3 activation. This research provides evidence for a critical role for CCL20 in autoimmune pathogenesis of the central nervous system.
The findings suggest that CCL20 production is influenced by IL-6 amplifier activation, which involves NF-κB and STAT3 activation. This research provides evidence for the critical role of CCL20 in the pathogenesis of autoimmune disorders within the central nervous system.