It is still considered a homolog of frizzled because it contains a Cysteine Rich Domain (CRD), and because of its intracellular C-terminus which is crucial for signaling. The CRD is highly conserved in diverse proteins, such as receptor tyrosine kinases and functions as a ligand binding domain.
It remains classified as a homolog of frizzled because it possesses a Cysteine Rich Domain (CRD) and an intracellular C-terminus that is vital for signaling. The CRD is highly conserved in diverse proteins, including receptor tyrosine kinases, and functions as a ligand binding domain.