It passes by the cities of Villaguay, Rosario del Tala, and Gualeguay, and finally empties into the Río Paraná Ibicuy, a distributary of the Paraná River in the Paraná Delta.
The river flows past Villaguay, Rosario del Tala, and Gualeguay before emptying into the Río Paraná Ibicuy, a tributary of the Paraná River in the Paraná Delta.