The Clyde River rises in the reservoirs of Lake Sorell and Lake Crescent, near Interlaken and flows generally west by south, through the settlements of  and , joined by nine minor tributaries before reaching its mouth and emptying into the River Derwent at Lake Meadowbank.
The Clyde River originates in Lake Sorell and Crescent reservoirs near Interlaken, flowing southwest through towns like  and , joined by nine smaller tributaries before emptying into the Derwent River at Lake Meadowbank.