By displaying that the decay of G-CSF mRNA, in the presence of actinomycin D, was slower in SB203580-treated cells. SB203580 increased the stability of G-CSF mRNA.
The observation that the breakdown of G-CSF mRNA was slowed down in the presence of actinomycin D in cells treated with SB203580 suggests that SB203580 can protect or stabilize G-CSF mRNA, thereby preventing its premature degradation.