In June 1765 Osei Kwadwo waged war on the alliance. The armies of Wassa and Twifo escaped to Fante territory but the Akyem were defeated.
Osei Kwadwo's military campaign in June 1765 led to a clash with the alliance, resulting in the Wassa and Twifo forces retreating into Fante territory, where they were ultimately defeated by the Akyem.