The focus of his scientific activities was on the characterization of the development of localized fungal infections of the skin and related mucosal surfaces. He concentrated on secreted aspartic proteases of Candida albicans as virulence factors and toll-like receptors as relevant mediators of the inflammatory host response. It was his prime concern to develop active pharmaceutical ingredients for the treatment and prevention of fungal infections reflecting the increased understanding of pathogenesis.
His research focused on fungal skin and mucosal infections, specifically on Candida albicans' secreted aspartic proteases as virulence factors and toll-like receptors as key mediators of the inflammatory host response. His work aimed to develop active pharmaceutical ingredients for treating and preventing fungal infections based on a growing understanding of their pathogenesis.