Blood from DEA 1.1 positive dogs should never be transfused into DEA 1.1 negative dogs. If it is the dog's first transfusion the red cells transfused will have a shortened life due to the formation of alloantibodies to the cells themselves and the animal will forever be sensitized to DEA 1.1 positive blood.
Transfusions of blood from DEA 1.1 positive dogs should never be given to DEA 1.1 negative dogs. If this is the dog's first transfusion, the transfused red blood cells will have a shorter lifespan due to the formation of antibodies against them, and the animal will become permanently sensitized to DEA 1.1 positive blood.