In 1848 he returned to Naples and was instrumental in the events leading King Ferdinand II to issue a Constitution. On 15 May 1848 Romano was again arrested and condemned to death, but managed to turn it into exile, moving to Montpellier in France.
In 1848 Romano's actions in Naples set off a chain of events that prompted King Ferdinand II to adopt a Constitution. His second arrest on 15 May 1848 led to a death sentence, but he was able to turn the situation to his advantage, ultimately choosing exile and moving to Montpellier, France.