RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane.
Receptor-activating molecules are transmembrane proteins consisting of an outer terminal and an inner terminal, which is located within the cell cytoplasm. These molecules are essential for transporting the calcitonin-receptor-like receptor (CRLR) to the cell surface.