The carboxy terminal domain of the enzyme consists of amino acids 132–341 and it harbours the active site of the enzyme. The overall structure of this domain shares a great deal of structural resemblance to the catalytic domain of other enzymes of the same family such as λ Integrase and HP1 Integrase.
The carboxy terminal region of the enzyme comprises amino acids 132–341 and it houses the active site of the enzyme. The overall structure of this domain exhibits a considerable degree of structural similarity to the catalytic domain of other enzymes belonging to the same family, such as λ Integrase and HP1 Integrase.