Once chemical activity is factored into the correct form of the equation, a dimensionless value is obtained. For the binding of receptor and ligand molecules in solution, the molar Gibbs free energy ΔG, or the binding affinity is related to the dissociation constant Kd via
When chemical activity is factored into the proper equation format, a dimensionless value is produced. In the context of receptor-ligand binding in solution, the molar Gibbs free energy ΔG, or binding affinity, is linked to the dissociation constant Kd through...