When a cause for MUPS is found, the symptom(s) are no longer medically unexplained. Some cases of ulcers and dyspepsia were considered MUPS until bacterial infections were found to be their cause.
When a cause for MUPS is identified, the symptoms are no longer considered medically unaccounted for. Many instances of ulcers and dyspepsia were previously categorized as MUPS but were reclassified after identifying bacterial infections as their causes.