Sugars have an overwhelming effect on gene expression. In yeast, glucose levels are managed by controlling the mRNA levels of hexose  transporters, while in mammals, the response to glucose is more tightly controlled with glucose metabolism and is therefore much more complex.
Sugars exert a powerful influence on gene expression. Yeast regulates glucose levels by managing the mRNA levels of hexose transporters, whereas mammalian responses are more intricate, relying on glucose metabolism for control.