The enzyme contains two major domains, responsible for the aminotransferase and synthase activity, respectively. The amidotransferase domains are located away from the tetramer interfaces and are not affected by the oligomeric state.
The enzyme's functionality is divided into two main components: one responsible for aminotransferase activity and the other for synthase activity. The amidotransferase sections are located on the outer surface of the tetramers and do not change with the oligomer's structure.