The RNA polymerase holoenzyme binds to a promoter of an exposed DNA strand and begins to synthesize the new strand of RNA. The double helix DNA is unwound and a short nucleotide sequence is accessible on each strand.
The RNA polymerase holoenzyme binds to a promoter on an exposed DNA strand and begins synthesizing a new RNA strand. The double helix DNA is unzipped, revealing a short nucleotide sequence on each strand.