With NDO, there is overactivity of the bladder wall muscle, which normally relaxes to allow storage of urine. The bladder wall muscle overactivity results in sporadic bladder muscle contraction, which increases pressure in the bladder and decreases the volume of urine the bladder can hold.
With NDO, there is an issue with the bladder's normal relaxation process, leading to increased bladder wall muscle activity and subsequent sporadic contractions that reduce the bladder's capacity for urine storage.