Each new strain is given a unique number and registered with the U.S. EPA and allowances may be given for genetic modification depending on "its parental strains, the proposed pesticide use pattern, and the manner and extent to which the organism has been genetically modified".
For each newly developed strain, a distinct number is assigned, and registration with the U.S. EPA is required. The approval for genetic modification depends on factors like the parent strains, the planned use of pesticides, and the degree of genetic alteration in the organism.