The white compound is enzymatically reduced to red TPF (1,3,5-triphenylformazan) in living tissues due to the activity of various dehydrogenases (enzymes important in oxidation of organic compounds and thus cellular metabolism), while it remains as white TTC in areas of necrosis since these enzymes have been either denatured or degraded.
The white compound is enzymatically converted into red TPF (1,3,5-triphenylformazan) in living tissues thanks to the activity of various dehydrogenases (enzymes important for organic compound oxidation and cellular metabolism), whereas it remains as white TTC in necrotic areas because these enzymes have been denatured or degraded.