In 1537 Flecha moved to Sigüenza where he served as maestro di cappella for two years. From 1544 to 1548 he lived in the castle at Arévalo as teacher of the Infantas Maria and Joanna, daughters of Charles V, Holy Roman Emperor (1500-1558).
Flecha's relocation to Sigüenza in 1537 led him to serve as a chapel director for two years. He then spent time at the castle at Arévalo from 1544 to 1548, educating the Infantas Maria and Joanna, daughters of Charles V.