Artabanus IV soon clashed with the Roman emperor Caracalla, whose forces he managed to contain at Nisibis in 217. Peace was made between the two empires the following year, with the Arsacids keeping most of Mesopotamia.
Artabanus IV confronted Roman emperor Caracalla in 217 at Nisibis, where he successfully contained the enemy's troops. Peace was eventually made between the two empires, with the Arsacids retaining a significant portion of Mesopotamia.