It runs in a southwest-to-northeast direction, from the main gate of Naval Base Guam in the southwestern village of Santa Rita in a northeasterly direction to the main gate of Andersen Air Force Base in the village of Yigo. It passes through Guam's capital, Hagåtña, as well as intersecting other territorial highways. The highway runs through tropical forest, urbanized commercial areas, and residential neighborhoods.
The road runs from Naval Base Guam to Andersen Air Force Base, passing through Santa Rita, Hagåtña, and Yigo. It travels through various landscapes including forests, towns, and residential areas.