Toni Gabaldón and Martijn Huynen (2003) reconstructed the proteome (the entire set of proteins expressed by a genome) and corresponding metabolism of the proto-mitochondrion by comparing extant alpha-proteobacterial and eukaryotic genomes.
In 2003, Toni Gabaldón and Martijn Huynen analyzed the proteome and metabolic pathways of the ancestral mitochondria (proto-mitochondrion) by comparing modern alpha-proteobacteria and eukaryotic genomes.