Rothblatt is a well-known voice for medical and pharmaceutical innovation. In 1994, motivated by her daughter being diagnosed with life-threatening pulmonary hypertension, Rothblatt created the PPH Cure Foundation and in 1996 founded United Therapeutics. That same year, she says, she had sex reassignment surgery.
Rothblatt is a prominent figure in the fields of medical and pharmaceutical advancement. In 1994, driven by her daughter's diagnosis with severe pulmonary hypertension, Rothblatt established the PPH Cure Foundation and co-founded United Therapeutics that same year. Additionally, she underwent sex reassignment surgery in 1996.