Deficiency in PFK leads to glycogenosis type VII (Tarui's disease), an autosomal recessive disorder characterised by severe nausea, vomiting, muscle cramps and myoglobinuria in response to bursts of intense or vigorous exercise.
Deficiency in PFK leads to glycogenosis type VII (Tarui's disease), an autosomal recessive disorder characterized by severe nausea, vomiting, muscle cramps and myoglobinuria in response to intense or strenuous physical exertion.