Following the discovery of its activity as a potent negative allosteric modulator of mGluR5, fenobam has been re-investigated for many applications, with its profile of combined antidepressant, anxiolytic, analgesic and anti-addictive effects potentially useful given the common co-morbidity of these symptoms.
Following the identification of its strong negative regulatory effect on mGluR5, fenobam has been re-investigated for various applications, with its extensive profile of antidepressant, anxiolytic, analgesic, and anti-addictive properties potentially advantageous in view of the commonality of these symptoms.