The Yukon Delta National Wildlife Refuge is a United States National Wildlife Refuge covering about  in southwestern Alaska. It is the second-largest National Wildlife Refuge in the country, only slightly smaller than the Arctic National Wildlife Refuge. It is a coastal plain extending to the Bering Sea, covering the delta created by the Yukon and Kuskokwim rivers.
The Yukon Delta National Wildlife Refuge is situated in southwestern Alaska, covering an area of approximately  and featuring a vast coastal plain that extends into the Bering Sea. As the second-largest refuge in the country, it is only slightly smaller than the Arctic National Wildlife Refuge. The refuge encompasses the delta formed by the confluence of the Yukon and Kuskokwim rivers.