As a member of the Argentine senior men's national basketball team, Prigioni played at the 2006 FIBA World Championship. He won silver medals at the 2003 FIBA Americas Championship and 2007 FIBA Americas Championship.
As a member of the Argentine senior men's national basketball team, Prigioni participated in the 2006 FIBA World Championship. He secured silver medals at the 2003 FIBA Americas Championship and 2007 FIBA Americas Championship.