When Pope Paul IV imposed the rule of cloister on the Angelicals, whom their foundress had destined for works of active charity, particularly the care of the sick and orphans, in 1557 she instituted another community, also at Milan, for whom she built a house between the Roman and the Tosa gate, known as the Collegio della Guastalla.
In 1557, Pope Paul IV imposed a rule of seclusion on the Angelicals, who were intended for active charity work, particularly caring for the sick and orphans.  The founder then established another community in Milan, known as the Collegio della Guastalla, which was built between the Roman and Tosa gates.