Pneumonia, for example, is generally confined to one or both lungs but can become disseminated through sepsis, in which the microorganism responsible for the pneumonia "seeds" the bloodstream or lymphatic system and is transported to distant sites in the body.
Pneumonia typically confines itself to one or both lungs but can become a systemic infection through sepsis, where the pneumonia-causing microbe is transported from the lungs to other parts of the body via the bloodstream or lymphatic system.