In 1878 Dr. DuBose married Mrs. Louise Yerger, headmistress at Fairmount College for Young Ladies in Monteagle, Tennessee at a service held in the parlor of the school.
Dr. DuBose tied the knot with Mrs. Louise Yerger, the head of a prestigious school for girls in Monteagle, Tennessee, in 1878, and the wedding celebration took place in the school's homey parlor.