Craven used the Gen-factor on many subjects, but all either died, went insane or mutated into monstrous beings. He finally succeeded with Team 7 and the survivors of the experiment were labeled Gen12. Later other Gen12-superhumans were seen, but the Team 7 members appeared to be the most successful and the most powerful of the Gen12.
Craven's experiments using the Gen-factor on numerous subjects ended in catastrophe – all perished, lost their sanity, or evolved into terrifying creatures. However, he eventually achieved success with a team of superhumans, which was later labeled as Gen12. The emergence of other Gen12 individuals highlighted Team 7's exceptional abilities and power.