The BMP-15 gene is located on the X-chromosome and using Northern blot analysis BMP-15 mRNA is locally expressed within the ovaries in oocytes only after they have started to undergo the primary stages of development. BMP-15 is translated as a preproprotein that is composed of a single peptide, which contains a proregion and a smaller mature region.
The BMP-15 gene's location on the X-chromosome and its expression within the ovaries in oocytes, as revealed by Northern blot analysis, occurs only after they have started their initial stages of development. The BMP-15 gene is translated into a preproprotein consisting of a single peptide with a proregion and a smaller mature portion.