Infusion of Ucn2 into rat hearts resulted in an immediate and significant improvement in left ventricle function, increased coronary flow, significantly altered intracellular calcium handling and increased SR calcium. These relaxation effects can be explained by the increased calcium clearance into the SR would assist in relaxation of the cell.
The infusion of Ucn2 into rat hearts resulted in notable improvements in heart function and increased blood supply, which can be attributed to its influence on the cell's ability to relax, resulting from enhanced calcium removal from the cell.