ACA70 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein.
ACA70's origins in HeLa cells highlight its classification among the snoRNA family known as H/ACA box, distinguished by its structural features and conservation of specific sequences. Its connection to the GAR1 protein underscores its functional role.