Further work into this with miR-6-depleted blastoderm embryos found pole cell formation at the posterior end of the anteroposterior axis to be disrupted, despite normality of both cellularisation and early pattern formation.
Further investigation into miR-6-depleted blastoderm embryos showed that the development of pole cells at the posterior end of the body axis was disrupted, whereas cellularization and early patterning were unaffected.