Later in 2000, Duno made her American Le Mans Series debut; she was the first woman to finish in a class podium on this championship. She made her 24 Hours of Daytona debut the next year and her 24 Hours of Le Mans debut a year later.
Duno's racing career took off in 2000 when she competed in the American Le Mans Series, becoming the first woman to achieve a podium finish in a class. She followed this with her debut at the 24 Hours of Daytona and then the 24 Hours of Le Mans.