As a central player in the Protein Structure Initiative, their Toronto team contributed to more than a thousand new microbial protein structures over the next decade, developed new crystallization methods, and used structural methods to de-orphanize several nuclear receptors and study ion transport across membranes.
As a major player in the Protein Structure Initiative's Toronto team, they made substantial contributions over the next decade, including the creation of more than 1,000 microbial protein structures, novel crystallization methods, and structural analysis to uncover orphan nuclear receptors and study ion transport across cell membranes.