Monobactams are effective only against aerobic Gram-negative bacteria (e.g., Neisseria, Pseudomonas). Siderophore-conjugated monobactams show promise for the treatment of multi drug-resistant pathogens.
Monobactams are only effective against aerobic Gram-negative bacteria like Neisseria and Pseudomonas.  However, conjugated siderophores with monobactams have potential as a treatment for multidrug-resistant pathogens.