Acrydite-modified oligonucleotides can react with nucleophiles such as thiols (Michael addition chemistry), this forms the basis of the ez-rays chemistry which was used for microarrays. More importantly, Acrydite-modified oligonucleotides can be incorporated, stoichiometrically, into hydrogels such as polyacrylamide, using standard free radical polymerization chemistry, where the double bond in the Acrydite group reacts with other activated double bond containing compounds such as acrylamide.
Acrydite-modified oligonucleotides can react with nucleophiles like thiols (Michael addition chemistry), forming the basis of ez-rays chemistry used in microarrays.  Furthermore, Acrydite-modified oligonucleotides can be incorporated into hydrogels such as polyacrylamide using standard free radical polymerization chemistry, where the double bond in the Acrydite group reacts with other activated double bond containing compounds like acrylamide.