Around 330, Macarius the Egyptian established a monastic colony in the Wadi El Natrun (Scetis), far from cultivable land. In the 330s, Saint Amun founded Nitria, only  southeast of Alexandria, using the rules of Saint Anthony.
In the early 4th century, Macarius the Egyptian founded a remote monastic colony in Wadi El Natrun (Scetis), far from agricultural areas. Subsequently, around the same time, Saint Amun established Nitria, a nearby settlement southeast of Alexandria, which followed the teachings of Saint Anthony.