During the thirties of the 19th century, Loznica had 295 houses with 1203 people and became the centre of the administrative and political power of Podrinje. The education system started to develop and a hospital was set up (1882), construction of industrial buildings started, craftsmen, trade and banking started to develop.
During the 19th century's third decade, Loznica became a center of administrative and political power in Podrinje, with an expanding education system, a hospital established in 1882, industrial construction beginning, craftspeople, trade, and banking emerging.