The enzyme adenylosuccinate synthase carries out the reaction by the addition of aspartate to IMP and requires the input of energy from a phosphoanhydride bond in the form of guanosine triphosphate (GTP).
Adenylosuccinate synthase catalyzes the reaction by joining aspartate to inosine monophosphate (IMP) through an energy-requiring process that involves the hydrolysis of guanosine triphosphate (GTP).