The human 5HT-2c mRNA was predicted to be 2'O-methylated by the C/D box snoRNP HBII-52 at a position also subjected to A:I editing. HBI-36 has no documented RNA target.
In the context of human gene expression, the 5HT-2c mRNA is expected to undergo 2'O-methylation by the snoRNP complex HBII-52, a process that also involves A:I editing. In contrast, HBI-36's function remains unclear due to its lack of documented RNA targets.