Latexin is a structurally similar protein to TIG1. Latexin is the only mammalian carboxypeptidase inhibitor, although TIG1's proteolytic activity remains unexplored. Using a selective subtractive differential gene display, Jing and colleagues discovered that TIG1 expression was absent from malignant prostate carcinoma cell lines but present in benign tumor lines.
Latexin is a structurally analogous protein to TIG1. Latexin is the sole mammalian carboxypeptidase inhibitor, whereas TIG1's proteolytic capabilities remain unexamined. Researchers employed a selective subtractive differential gene display to determine that TIG1 expression was absent from malignant prostate carcinoma cell lines but present in benign tumor cell lines.