The route begins at a T-intersection with SR 309 in Washington Township. It heads a short distance east and immediately intersects SR 61. SR 288 curves to the east-northeast just past this junction, bounded by farmland on the south side and woods on the north side.
This route begins at a junction with SR 309 in a rural area of Washington Township. It proceeds eastward for a short time before intersecting SR 61. The highway then curves to the northeast just beyond this intersection, bounded by agricultural areas on one side and wooded land on the other.