En route, they were ordered to reinforce the escort group protecting convoy SC 42. On 10 September 1941, Moose Jaw along with Chambly  sank  by depth charges and ramming in the Denmark Strait south of Tasiilaq, Greenland.
As they journeyed, they received orders to augment the security detail protecting convoy SC 42. On 10 September 1941, Moose Jaw, accompanied by Chambly, was torpedoed and sunk by depth charges and ramming in the Denmark Strait off the coast of Tasiilaq, Greenland.