State Route 78 (SR 78) is a state highway that runs for 105 miles (169 km) from Nelsonville to Clarington in the U.S. state of Ohio. Car and Driver has called it one of the most scenic highways nationwide.
State Route 78 (SR 78), a state highway spanning 105 miles (169 km) between Nelsonville and Clarington, Ohio, is recognized by Car and Driver as one of the most visually appealing roads in the nation.