FCE 28260 has been found to inhibit rat and human 5α-reductase with half-maximal inhibitory concentrations (IC50) of 15 and 16 nM, respectively, while finasteride had values of 30 and 52 nM.
Research has revealed that FCE 28260 effectively reduces the activity of rat and human 5α-reductase enzymes with IC50 values of 15 and 16 nM, respectively. In comparison, finasteride demonstrated lower potency in inhibiting these enzymes, with IC50 values of 30 and 52 nM.