Phage T7 has the simplest known DNA replisome, consisting of a helicase and primase that reside in a single polypeptide chain that forms a hexamer in the presence of DNA and ATP or dTTP.
Phage T7 has the most basic known DNA replisome, comprising a helicase and primase that coexist in a single polypeptide chain forming a hexamer upon DNA binding and ATP or dTTP presence.