Positive antibody staining for gephyrin at a synapse is most of the time consistent with the presence of glycine and/or GABAA receptors. Nevertheless, some exceptions can occur like in neurons of Dorsal Root Ganglions where gephyrin is absent despite the presence of GABAA receptors.
The presence of positive antibody staining for gephyrin at a synapse typically signifies the presence of glycine and/or GABAA receptors. However, exceptions can be found in neurons of Dorsal Root Ganglions where gephyrin is absent despite the presence of GABAA receptors.