Using (E)-3-(2-acetamido-4-chlorophenyl)acrylic acid, (S)-(4-(4-fluorobenzyl)piperazin-2-yl)methanol to produce (S,E)-N-(5-chloro-2-(3-(4-(4-fluorobenzyl)-2-(hydroxymethyl)piperazin-1-yl)-3-oxoprop-1-en-1-yl)phenyl)acetamide, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
