Using (E)-3,5-diamino-6-chloro-N-(1,3,8-triazaspiro[4.5]decan-2-ylidene)pyrazine-2-carboxamide, 3-((4-isobutoxypiperidin-1-yl)sulfonyl)benzoic acid to produce (E)-3,5-diamino-6-chloro-N-(8-(3-((4-isobutoxypiperidin-1-yl)sulfonyl)benzoyl)-1,3,8-triazaspiro[4.5]decan-2-ylidene)pyrazine-2-carboxamide, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
