Using 1-chloro-4-(chloromethyl)benzene, (E)-3-(3-chloro-4-((5-hydroxypyridin-2-yl)oxy)-5-methylphenyl)-1-(4-(4-(2-(p-tolyloxy)ethyl)benzyl)piperazin-1-yl)prop-2-en-1-one to produce (E)-3-(3-chloro-4-((5-((4-chlorobenzyl)oxy)pyridin-2-yl)oxy)-5-methylphenyl)-1-(4-(4-(2-(p-tolyloxy)ethyl)benzyl)piperazin-1-yl)prop-2-en-1-one, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
