Using pyrimidin-5-ylboronic acid, (R)-3-(4-((6-chloropyridin-3-yl)sulfonyl)-2-cyclohexyl-6-oxopiperazin-1-yl)-5-phenylthiophene-2-carboxylic acid to produce (R)-3-(2-cyclohexyl-6-oxo-4-((6-(pyrimidin-5-yl)pyridin-3-yl)sulfonyl)piperazin-1-yl)-5-phenylthiophene-2-carboxylic acid, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
