Using (R)-2-chloro-3-(2-methylpiperazin-1-yl)pyrazine, 2-((2-(2-(dimethylamino)ethoxy)pyridin-3-yl)oxy)ethan-1-ol to produce (R)-N,N-dimethyl-2-((3-(2-((3-(2-methylpiperazin-1-yl)pyrazin-2-yl)oxy)ethoxy)pyridin-2-yl)oxy)ethan-1-amine, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
