Using 3,3-dimethylbut-1-yne, methyl 5-iodo-3-((1r,4r)-4-methyl-N-(1,4-dioxaspiro[4.5]decan-8-yl)cyclohexane-1-carboxamido)thiophene-2-carboxylate to produce methyl 5-(3,3-dimethylbut-1-yn-1-yl)-3-((1r,4r)-4-methyl-N-(1,4-dioxaspiro[4.5]decan-8-yl)cyclohexane-1-carboxamido)thiophene-2-carboxylate, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
