Using N-(tert-butoxycarbonyl)-N-methylglycine, (R)-2,6-dichloro-4-methyl-N-(3-(4-((thiophen-3-ylmethyl)amino)piperidin-1-yl)butyl)nicotinamide to produce (R)-2,6-dichloro-4-methyl-N-(3-(4-(2-(methylamino)-N-(thiophen-3-ylmethyl)acetamido)piperidin-1-yl)butyl)nicotinamide, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
