Using 1-methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine, (R)-1-(2-(((7-chloropyrido[3,4-b]pyrazin-5-yl)amino)methyl)morpholino)-2,2-difluoroethan-1-one to produce (R)-2,2-difluoro-1-(2-(((7-(4-(4-methylpiperazin-1-yl)phenyl)pyrido[3,4-b]pyrazin-5-yl)amino)methyl)morpholino)ethan-1-one, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
