Using (S)-6-azaspiro[2.5]octan-4-ol, (S,E)-3-(4-(3-(3-chloro-4-fluorophenyl)acryloyl)-3-methyl-2-oxopiperazin-1-yl)propanoic acid to produce (S)-4-((E)-3-(3-chloro-4-fluorophenyl)acryloyl)-1-(3-((S)-4-hydroxy-6-azaspiro[2.5]octan-6-yl)-3-oxopropyl)-3-methylpiperazin-2-one, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
