Using (R)-2-(6-fluoro-3-oxo-1,5-dihydropyrrolo[4,3,2-de][2,6]naphthyridin-4(3H)-yl)-3-methylbutanoic acid, thiomorpholine 1,1-dioxide to produce (R)-4-(1-(1,1-dioxidothiomorpholino)-3-methyl-1-oxobutan-2-yl)-6-fluoro-4,5-dihydropyrrolo[4,3,2-de][2,6]naphthyridin-3(1H)-one, please predict the condition, including solvent and agent in SMILES notation in json format like:

```JSON
{
    "solvent": [
        "CCN(CC)CC",
        "CCOC(C)=O"
    ],
    "agent": [
        "On1nnc2ccccc21",
        "C(=NC1CCCCC1)=NC1CCCCC1",
        "Cl"
    ]
}
```
