Polymerase chain reaction
Developed in 1983 by Kary Mullis, PCR is now a common and often indispensable technique used in clinical and research laboratories for a broad variety of applications. These include DNA cloning for sequencing, gene cloning and manipulation, gene mutagenesis; construction of DNA - based phylogenies, or functional analysis of genes; diagnosis and monitoring of hereditary diseases; amplification of ancient DNA; analysis of genetic fingerprints for DNA profiling (for example, in forensic science and parentage testing); and detection of pathogens in nucleic acid tests for the diagnosis of infectious diseases. In 1993, Mullis was awarded the Nobel Prize in Chemistry along with Michael Smith for his work on PCR.
Genome
New sequencing technologies, such as massive parallel sequencing have also opened up the prospect of personal genome sequencing as a diagnostic tool, as pioneered by Manteia Predictive Medicine. A major step toward that goal was the completion in 2007 of the full genome of James D. Watson, one of the co-discoverers of the structure of DNA.
Central Intelligence Agency
Unlike the Federal Bureau of Investigation (FBI), which is a domestic security service, CIA has no law enforcement function and is mainly focused on overseas intelligence gathering, with only limited domestic collection. Though it is not the only U.S. government agency specializing in HUMINT, CIA serves as the national manager for coordination and deconfliction of HUMINT activities across the entire intelligence community. Moreover, CIA is the only agency authorized by law to carry out and oversee covert action on behalf of the President, unless the President determines that another agency is better suited for carrying out such action. It can, for example, exert foreign political influence through its tactical divisions, such as the Special Activities Division.
Rosser Reeves
Rosser Reeves (10 September 1910 – 24 January 1984) was an American advertising executive and pioneer of television advertising; Reeves generated millions for his clients. The Ted Bates agency, where he rose to chairman, exists today as Bates CHI & Partners.
Genome
The proportion of repetitive DNA is calculated by using length of repetitive DNA divide by genome size. There are two categories of repetitive DNA in genome: tandem repeats and interspersed repeats.
Frank Simoes
Frank Simoes (1937–2002) was an Indian writer and pioneering advertising executive, the first Indian to set up his own advertising agency, born in Mumbai.
Zeke Zechella
Alexander Philip "Zeke" Zechella (August 11, 1920 - August 15, 2009) was a United States Navy veteran and pioneer in the usage of nuclear energy who headed several major companies before retiring in Jacksonville, Florida and assisting local non-profit agencies.
Joseph Smith
Smith was born on December 23, 1805 in Sharon, Vermont to Lucy Mack Smith and her husband Joseph Sr., a merchant and farmer. Modern DNA testing of Smith's relatives suggests that his family were of Irish descent, as he carried a rare Y-DNA marker within Haplogroup R1b which is found almost entirely in people of Northwestern Irish descent.
AAI RQ-2 Pioneer
The AAI RQ-2 Pioneer is an unmanned aerial vehicle (UAV) that had been utilized by the United States Navy, Marine Corps, and Army, and deployed at sea and on land from 1986 until 2007. Initially tested aboard USS "Iowa", the RQ-2 Pioneer was placed aboard s to provide gunnery spotting, its mission evolving into reconnaissance and surveillance, primarily for amphibious forces.
Federal Bureau of Investigation
The FBI Laboratory, established with the formation of the BOI, did not appear in the J. Edgar Hoover Building until its completion in 1974. The lab serves as the primary lab for most DNA, biological, and physical work. Public tours of FBI headquarters ran through the FBI laboratory workspace before the move to the J. Edgar Hoover Building. The services the lab conducts include Chemistry, Combined DNA Index System (CODIS), Computer Analysis and Response, DNA Analysis, Evidence Response, Explosives, Firearms and Tool marks, Forensic Audio, Forensic Video, Image Analysis, Forensic Science Research, Forensic Science Training, Hazardous Materials Response, Investigative and Prospective Graphics, Latent Prints, Materials Analysis, Questioned Documents, Racketeering Records, Special Photographic Analysis, Structural Design, and Trace Evidence. The services of the FBI Laboratory are used by many state, local, and international agencies free of charge. The lab also maintains a second lab at the FBI Academy.
William Sealy Gosset
William Sealy Gosset (13 June 1876 – 16 October 1937) was Head Brewer of Guinness, Head Experimental Brewer of Guinness, and a pioneer of modern statistics. He pioneered small sample experimental design and analysis with an economic approach to the logic of uncertainty. Gosset published under the pen name Student and developed most famously Student's t-distribution - originally called Student's "z" - and "Student's test of statistical significance".
Helén murder
The Helén murder () is a sadistic murder of 10-year-old Helén Nilsson in Hörby, Sweden, in March 1989. The murderer, Ulf Olsson, the so-called Helén man ("Helén-mannen"), was convicted in April 2005, having been found after a DNA test in 2004.
Mitochondrial DNA
Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants and algae, also in plastids such as chloroplasts.
Sacramento McClellan Airport
The air force base was established in 1935. It was named after Major Hezekiah McClellan on 1 December 1939, a pioneer in arctic aeronautical tests. Born in 1894, he died on 25 May 1936 when his Consolidated P - 30 which he was flight testing, crashed near Centerville, Ohio.
Pioneer 3
Pioneer 3 was a spin stabilized spacecraft launched at 05:45:12 UTC on 6 December 1958 by the U.S. Army Ballistic Missile Agency in conjunction with the NASA, using a Juno II rocket. This spacecraft was intended as a lunar probe, but failed to go past the Moon and into a heliocentric orbit as planned, but did reach an altitude of 102,360 km before falling back to Earth. The revised spacecraft objectives were to measure radiation in the outer Van Allen radiation belt using two Geiger-Müller tubes and to test the trigger mechanism for a lunar photographic experiment.
Federal Bureau of Investigation
From the end of the 1980s to the early 1990s, the FBI reassigned more than 300 agents from foreign counter-intelligence duties to violent crime, and made violent crime the sixth national priority. With reduced cuts to other well-established departments, and because terrorism was no longer considered a threat after the end of the Cold War, the FBI assisted local and state police forces in tracking fugitives who had crossed state lines, which is a federal offense. The FBI Laboratory helped develop DNA testing, continuing its pioneering role in identification that began with its fingerprinting system in 1924.
Daniel Morar
Daniel Marius Morar (born August 15, 1966) is a Romanian jurist, who was Chief Prosecutor of the Romanian National Anticorruption Directorate (DNA), the agency responsible for investigating, preventing and prosecuting corruption-related offenses. The National Anticorruption Directorate under Morar's leadership is credited as one of the pivotal actors in Romania's anti-corruption fight. Since 2013 he has been a supreme judge on Romania's Constitutional Court.
STR analysis
STR analysis is a tool in forensic analysis that evaluates specific STR regions found on nuclear DNA. The variable (polymorphic) nature of the STR regions that are analyzed for forensic testing intensifies the discrimination between one DNA profile and another. Forensic science takes advantage of the population's variability in STR lengths, enabling scientists to distinguish one DNA sample from another. The system of DNA profiling used today is based on PCR and uses simple sequences or short tandem repeats (STR). This method uses highly polymorphic regions that have short repeated sequences of DNA (the most common is 4 bases repeated, but there are other lengths in use, including 3 and 5 bases). Because unrelated people almost certainly have different numbers of repeat units, STRs can be used to discriminate between unrelated individuals. These STR loci (locations on a chromosome) are targeted with sequence - specific primers and amplified using PCR. The DNA fragments that result are then separated and detected using electrophoresis. There are two common methods of separation and detection, capillary electrophoresis (CE) and gel electrophoresis.
Sunil Gavaskar
Sunil Manohar ``Sunny ''Gavaskar pronunciation (help info) (born 10 July 1949) is a former Indian international cricketer who played from the early 1970s to late 1980s for the Bombay cricket team and Indian national team. Widely regarded as one of the greatest Test batsmen and best opening batsmen in Test cricket history, Gavaskar set world records during his career for the most Test runs and most Test centuries scored by any batsman. He held the record of 34 Test centuries for almost two decades before it was broken by Sachin Tendulkar in December 2005. He was the first person to score centuries in both innings of a Test match three times. He was the first Test batsman to score 10,000 Test Runs in a Career and now stands at number 12 on the group of 13 players with 10,000 + Test Runs.
Eyewitness testimony
Psychologists have probed the reliability of eyewitness testimony since the beginning of the 20th century. One prominent pioneer was Hugo Münsterberg, whose controversial book On the Witness Stand (1908) demonstrated the fallibility of eyewitness accounts, but met with fierce criticism, particularly in legal circles. His ideas did, however, gain popularity with the public. Decades later, DNA testing would clear individuals convicted on the basis of errant eyewitness testimony. Studies by Scheck, Neufel, and Dwyer showed that many DNA - based exonerations involved eyewitness evidence.
What is the full name of the agency with a three letter abbreviation that pioneered DNA testing?
What agency pioneered DNA testing?
The FBI
What does #1 stand for?
Federal Bureau of Investigation