Still there have been some signs of a turnaround before Friday. Apogee Therapeutics and Sagimet Biosciences which both went public in July upsized their IPOs and offered more shares than originally planned. And on Wednesday British chip designer Arm raised nearly 49 billion in the largest IPO to list on Nasdaq this year;  an event The New York Times likened to Wall Streets Groundhog Day Arms doubledigit stock gains on Thursday along with the news from RayzeBio and Neumora might indicate sunnier days ahead