Nineteen years later, their son Philip the Handsome married Joanna of Castile, daughter of King Ferdinand II of Aragon and Queen Isabella I of Castile. Joanna (also known as Juanna the Mad) was sister to Katherine (of Aragon), the first wife of Henry VIII of England. Following the death of her brother and two sisters, Joanna became heiress to the Spanish throne.
Katherine
Joanna