Alice's eldest daughter, Anne Stanley, Countess of Castlehaven was heir presumptive to Queen Elizabeth I. She married secondly in 1600 Thomas Egerton, 1st Viscount Brackley. Alice was born in Althorpe, Northamptonshire, England on 4 May 1559, the youngest daughter of Sir John Spencer, Member of Parliament and High Sheriff of Northamptonshire, and Katherine Kytson. She had three brothers and three older sisters.
Alice
Katherine Kytson