Friederike was born in Darmstadt, the eldest daughter of Prince George William of Hesse-Darmstadt, second son of Louis VIII, Landgrave of Hesse-Darmstadt, and Countess Maria Louise Albertine of Leiningen-Falkenburg-Dagsburg. She married Duke Charles of Mecklenburg-Strelitz on 18 September 1768 in Darmstadt.
Friederike
Countess Maria Louise Albertine