The Parties hereby agree that the Combination Agreement, including all schedules and exhibits thereto, and all ancillary agreements contemplated thereby, including the Ancillary Agreements (other than the Confidentiality Agreement) and the irrevocable undertakings executed by certain shareholders of Oxford in favor of Cambridge and Oxford (collectively, the “ Transaction Documents ”), are hereby terminated effective immediately (the “ Termination Time ”) and, notwithstanding anything to the contrary in the Transaction Documents, including Section 11.2 of the Combination Agreement, the Transaction Documents are terminated in their entirety and shall become null and void and be of no further force or effect whatsoever (the “ Termination ”).