human
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['This study evaluated whether specific patterns of Interleukin-1 (IL-1) gene variants, known to affect periodontitis severity, influenced the previously reported association between obesity and subsequent periodontitis progression in a longitudinal database. The population included 292 men (ages 29-64 at entry) from the Veterans Affairs Dental Longitudinal Study (DLS) from whom DNA was collected and had dental and anthropometric endpoints collected over multiple examinations (approximately every 3 years for up to 27 years).', 'Key variables assessed included periodontitis, body mass index (BMI), waist circumference/height ratio (WC/Ht R) for central adiposity, age, smoking, glucose tolerance, and two previously reported versions of IL-1 genetic patterns associated with periodontitis severity and progression. Disease progression was determined using predefined criteria that utilized a combination of change in classification of disease severity based on alveolar bone loss and tooth loss during follow-up. Extended Cox regression analyses were used to estimate the hazards of experiencing periodontal disease progression with or without adjustments for appropriate covariates.', 'In hazard ratio analyses, men with WC/Ht R> 50% at baseline and positive for either IL-1 genotype version were at significantly higher risk (2-fold) for disease progression (p-for interaction= 0.04). Participants positive for IL-1 version 2 genotype exhibited earlier progression (fewer years from baseline to first incidence of progression) than those who were negative (p= 0.021; adjusted for age and smoking).'] Is influence of Obesity on Periodontitis Progression Conditional on IL-1 Inflammatory Genetic Variation?
OUTPUT:

agent
yes
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['This study evaluated whether specific patterns of Interleukin-1 (IL-1) gene variants, known to affect periodontitis severity, influenced the previously reported association between obesity and subsequent periodontitis progression in a longitudinal database. The population included 292 men (ages 29-64 at entry) from the Veterans Affairs Dental Longitudinal Study (DLS) from whom DNA was collected and had dental and anthropometric endpoints collected over multiple examinations (approximately every 3 years for up to 27 years).', 'Key variables assessed included periodontitis, body mass index (BMI), waist circumference/height ratio (WC/Ht R) for central adiposity, age, smoking, glucose tolerance, and two previously reported versions of IL-1 genetic patterns associated with periodontitis severity and progression. Disease progression was determined using predefined criteria that utilized a combination of change in classification of disease severity based on alveolar bone loss and tooth loss during follow-up. Extended Cox regression analyses were used to estimate the hazards of experiencing periodontal disease progression with or without adjustments for appropriate covariates.', 'In hazard ratio analyses, men with WC/Ht R> 50% at baseline and positive for either IL-1 genotype version were at significantly higher risk (2-fold) for disease progression (p-for interaction= 0.04). Participants positive for IL-1 version 2 genotype exhibited earlier progression (fewer years from baseline to first incidence of progression) than those who were negative (p= 0.021; adjusted for age and smoking).'] Is influence of Obesity on Periodontitis Progression Conditional on IL-1 Inflammatory Genetic Variation?
OUTPUT:
