human
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['Mechanical stimulation of the mucosal epithelium results in increased serotonin (5-HT) release from enterochromaffin (EC) cells. Little is known about how this process varies in different regions of the intestinal tract; however, purines are felt to play a role. We studied the relationship between mechanical stimulation, adenosine triphosphate (ATP), and 5-HT release from ileal and colonic mucosal tissue.', 'Amperometric recordings of ATP and 5-HT were carried out using an ATP biosensor and boron-doped diamond microelectrode. Levels of extracellular ATP and 5-HT were monitored using high performance liquid chromatography.', 'Under basal conditions, 5-HT levels were significantly decreased in the ileum (p\xa0<\xa00.001) but not the colon in the presence of the P2 antagonist suramin (100\xa0μM). Ecto-ATPase inhibitor ARL67156 (10\xa0μM) elevated ATP levels in the ileum and colon (both p\xa0<\xa00.001), but only 5-HT levels in the ileum (p\xa0<\xa00.001). Exogenous ATP increased 5-HT release in the presence of tetrodotoxin in the ileum (p\xa0<\xa00.001), but had not effect in the colon. Mechanical stimulation increased levels of 5-HT in the ileum (p\xa0<\xa00.001) and colon (p\xa0<\xa00.01), but levels returned to baseline in the presence of suramin and MRS2179 in the ileum. The onset of 5-HT release was delayed following mechanical stimulation. The rise time of the ATP response was quicker than that of 5-HT during mechanical stimulation.'] Does mucosal adenosine triphosphate mediate serotonin release from ileal but not colonic guinea pig enterochromaffin cells?
OUTPUT:

agent
yes
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['Mechanical stimulation of the mucosal epithelium results in increased serotonin (5-HT) release from enterochromaffin (EC) cells. Little is known about how this process varies in different regions of the intestinal tract; however, purines are felt to play a role. We studied the relationship between mechanical stimulation, adenosine triphosphate (ATP), and 5-HT release from ileal and colonic mucosal tissue.', 'Amperometric recordings of ATP and 5-HT were carried out using an ATP biosensor and boron-doped diamond microelectrode. Levels of extracellular ATP and 5-HT were monitored using high performance liquid chromatography.', 'Under basal conditions, 5-HT levels were significantly decreased in the ileum (p\xa0<\xa00.001) but not the colon in the presence of the P2 antagonist suramin (100\xa0μM). Ecto-ATPase inhibitor ARL67156 (10\xa0μM) elevated ATP levels in the ileum and colon (both p\xa0<\xa00.001), but only 5-HT levels in the ileum (p\xa0<\xa00.001). Exogenous ATP increased 5-HT release in the presence of tetrodotoxin in the ileum (p\xa0<\xa00.001), but had not effect in the colon. Mechanical stimulation increased levels of 5-HT in the ileum (p\xa0<\xa00.001) and colon (p\xa0<\xa00.01), but levels returned to baseline in the presence of suramin and MRS2179 in the ileum. The onset of 5-HT release was delayed following mechanical stimulation. The rise time of the ATP response was quicker than that of 5-HT during mechanical stimulation.'] Does mucosal adenosine triphosphate mediate serotonin release from ileal but not colonic guinea pig enterochromaffin cells?
OUTPUT:
