human
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['To investigate the placental expression of angiopoietin (Ang)-1, Ang-2 and their receptor, Tie-2, in preeclampsia (PE) with or without intrauterine growth restriction (IUGR).', 'Case-control study including placentas from 28\xa0PE pregnancies, 30\xa0PE-IUGR pregnancies and 40 controls. The expression status of the genes was evaluated by quantitative real-time PCR.', 'In both PE and PE-IUGR groups, compared to the control group, there was significantly higher expression of Ang-2 (p\xa0<\xa00.001) and Tie-2 (p\xa0=\xa00.008) and lower expression of Ang-1 (p\xa0=\xa00.001). The magnitude of the difference was similar for Ang-1 for both groups, whereas the magnitude of the differences was higher for Ang-2 and Tie-2 in PE-IUGR group compared to controls. Ang-2 and Tie-2 were correlated in both PE (r\xa0=\xa00.8602, p\xa0<\xa00.001) and PE-IUGR (r\xa0=\xa00.6342, p\xa0<\xa00.001) groups. In PE-IUGR group, Ang-1 was associated to Ang-2 (r\xa0=\xa00.3458, p\xa0=\xa00.0452) and Tie-2 (r\xa0=\xa00.4448, p\xa0=\xa00.0084). Log10Ang-1 but not Ang-2 was gestational age dependent (R2\xa0=\xa00.40, p\xa0<\xa00.001). After conversion in Multiples of the Median (MoM) log10 MoM Ang-1 was reduced in the PE group (mean\xa0=\xa0-0.8181, p\xa0<\xa00.001) and the PE-IUGR group (mean\xa0=\xa0-1.2583, p\xa0<\xa00.001) compared to control group (mean\xa0=\xa0-0.0924).'] Is placental mRNA expression of angiopoietins ( Ang ) -1 , Ang-2 and their receptor Tie-2 altered in pregnancies complicated by preeclampsia?
OUTPUT:

agent
yes
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['To investigate the placental expression of angiopoietin (Ang)-1, Ang-2 and their receptor, Tie-2, in preeclampsia (PE) with or without intrauterine growth restriction (IUGR).', 'Case-control study including placentas from 28\xa0PE pregnancies, 30\xa0PE-IUGR pregnancies and 40 controls. The expression status of the genes was evaluated by quantitative real-time PCR.', 'In both PE and PE-IUGR groups, compared to the control group, there was significantly higher expression of Ang-2 (p\xa0<\xa00.001) and Tie-2 (p\xa0=\xa00.008) and lower expression of Ang-1 (p\xa0=\xa00.001). The magnitude of the difference was similar for Ang-1 for both groups, whereas the magnitude of the differences was higher for Ang-2 and Tie-2 in PE-IUGR group compared to controls. Ang-2 and Tie-2 were correlated in both PE (r\xa0=\xa00.8602, p\xa0<\xa00.001) and PE-IUGR (r\xa0=\xa00.6342, p\xa0<\xa00.001) groups. In PE-IUGR group, Ang-1 was associated to Ang-2 (r\xa0=\xa00.3458, p\xa0=\xa00.0452) and Tie-2 (r\xa0=\xa00.4448, p\xa0=\xa00.0084). Log10Ang-1 but not Ang-2 was gestational age dependent (R2\xa0=\xa00.40, p\xa0<\xa00.001). After conversion in Multiples of the Median (MoM) log10 MoM Ang-1 was reduced in the PE group (mean\xa0=\xa0-0.8181, p\xa0<\xa00.001) and the PE-IUGR group (mean\xa0=\xa0-1.2583, p\xa0<\xa00.001) compared to control group (mean\xa0=\xa0-0.0924).'] Is placental mRNA expression of angiopoietins ( Ang ) -1 , Ang-2 and their receptor Tie-2 altered in pregnancies complicated by preeclampsia?
OUTPUT:
