human
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['Involvement of epidermal growth factor (EGF) is reported in diseases caused by hypoxia. Its functional polymorphism may alter its transcription, affecting EGF expression, contributing to obstructive sleep apnea (OSA).', 'The aim of this study was to investigate associations of EGF+61 polymorphism and risk of OSA.', 'Two hundred two participants were enrolled in this case-control study. DNA was extracted from peripheral blood, and EGF 61A/G polymorphism was determined using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay.', 'No significant association between EGF 61 A/G polymorphism and risk of OSA was observed in any of the gene models tested (AA vs. GG: OR\u2009=\u20090.97, 95% CI\u2009=\u20090.37-2.55; P\u2009=\u20090.95). However, compared with GG genotype, AG genotype associated with decreased risk of severe OSA (AG vs. GG: OR\u2009=\u20090.32, 95% CI\u2009=\u20090.11-0.94).'] Does a functional EGF+61 polymorphism is associate with severity of obstructive sleep apnea?
OUTPUT:

agent
yes
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['Involvement of epidermal growth factor (EGF) is reported in diseases caused by hypoxia. Its functional polymorphism may alter its transcription, affecting EGF expression, contributing to obstructive sleep apnea (OSA).', 'The aim of this study was to investigate associations of EGF+61 polymorphism and risk of OSA.', 'Two hundred two participants were enrolled in this case-control study. DNA was extracted from peripheral blood, and EGF 61A/G polymorphism was determined using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay.', 'No significant association between EGF 61 A/G polymorphism and risk of OSA was observed in any of the gene models tested (AA vs. GG: OR\u2009=\u20090.97, 95% CI\u2009=\u20090.37-2.55; P\u2009=\u20090.95). However, compared with GG genotype, AG genotype associated with decreased risk of severe OSA (AG vs. GG: OR\u2009=\u20090.32, 95% CI\u2009=\u20090.11-0.94).'] Does a functional EGF+61 polymorphism is associate with severity of obstructive sleep apnea?
OUTPUT:
