human
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['To assess ocular blood flow responses to acute IOP stress following 4\xa0weeks of chronic IOP elevation in streptozotocin (STZ)-induced diabetic and control rats. We hypothesise that chronic IOP elevation for 4\xa0weeks will further impair blood flow regulation in STZ-induced diabetic rats eyes.', 'Two weeks following citrate buffer or STZ-injections chronic IOP elevation was induced in Long Evans rats via fortnightly intracameral injections of microspheres (15\xa0μm) suspended in 5% polyethylene glycol. IOP was monitored daily. Electroretinography (ERG, -6.79-2.07 log cd\xa0s\xa0m(-2) ) was undertaken at Week 4 to compare photoreceptor (RmPIII ), ON-bipolar cell (Vmax ) and ganglion cell dominant ERG [scotopic threshold response (STR)] components. 4\xa0weeks post-chronic IOP induction, ocular blood flow (laser Doppler flowmetry) was measured in response to acute IOP challenge (10-100\xa0mmHg, in 5\xa0mmHg steps, each 3\xa0min).', 'Four weeks of chronic IOP (mean\xa0±\xa0S.E.M., citrate: 24.0\xa0±\xa00.3 to 30.7\xa0±\xa01.3 and STZ-diabetes: 24.2\xa0±\xa00.2 to 31.1\xa0±\xa01.2\xa0mmHg) was associated with reduced photoreceptor amplitude in both groups (-25.3\xa0±\xa02.2% and -17.2\xa0±\xa03.0%, respectively). STZ-diabetic eyes showed reduced photoreceptor sensitivity (citrate: 0.5\xa0±\xa01.8%, STZ-diabetic: -8.1\xa0±\xa02.4%). Paradoxically ON-bipolar cell sensitivity was increased, particularly in citrate control eyes (citrate: 166.8\xa0±\xa025.9%, STZ-diabetic: 64.8\xa0±\xa018.7%). The ganglion cell dominant STR was not significantly reduced in STZ-diabetic rats. Using acute IOP elevation to probe autoregulation, we show that STZ-diabetes impaired autoregulation compared with citrate control animals. The combination of STZ-diabetes and chronic IOP elevation further impaired autoregulation.'] Does chronic intraocular pressure elevation impair autoregulatory capacity in streptozotocin-induced diabetic rat retina?
OUTPUT:

agent
yes
TASK: Your task is to answer biomedical questions using the given abstract. Only output yes, no, or maybe as answer.
INPUT: ['To assess ocular blood flow responses to acute IOP stress following 4\xa0weeks of chronic IOP elevation in streptozotocin (STZ)-induced diabetic and control rats. We hypothesise that chronic IOP elevation for 4\xa0weeks will further impair blood flow regulation in STZ-induced diabetic rats eyes.', 'Two weeks following citrate buffer or STZ-injections chronic IOP elevation was induced in Long Evans rats via fortnightly intracameral injections of microspheres (15\xa0μm) suspended in 5% polyethylene glycol. IOP was monitored daily. Electroretinography (ERG, -6.79-2.07 log cd\xa0s\xa0m(-2) ) was undertaken at Week 4 to compare photoreceptor (RmPIII ), ON-bipolar cell (Vmax ) and ganglion cell dominant ERG [scotopic threshold response (STR)] components. 4\xa0weeks post-chronic IOP induction, ocular blood flow (laser Doppler flowmetry) was measured in response to acute IOP challenge (10-100\xa0mmHg, in 5\xa0mmHg steps, each 3\xa0min).', 'Four weeks of chronic IOP (mean\xa0±\xa0S.E.M., citrate: 24.0\xa0±\xa00.3 to 30.7\xa0±\xa01.3 and STZ-diabetes: 24.2\xa0±\xa00.2 to 31.1\xa0±\xa01.2\xa0mmHg) was associated with reduced photoreceptor amplitude in both groups (-25.3\xa0±\xa02.2% and -17.2\xa0±\xa03.0%, respectively). STZ-diabetic eyes showed reduced photoreceptor sensitivity (citrate: 0.5\xa0±\xa01.8%, STZ-diabetic: -8.1\xa0±\xa02.4%). Paradoxically ON-bipolar cell sensitivity was increased, particularly in citrate control eyes (citrate: 166.8\xa0±\xa025.9%, STZ-diabetic: 64.8\xa0±\xa018.7%). The ganglion cell dominant STR was not significantly reduced in STZ-diabetic rats. Using acute IOP elevation to probe autoregulation, we show that STZ-diabetes impaired autoregulation compared with citrate control animals. The combination of STZ-diabetes and chronic IOP elevation further impaired autoregulation.'] Does chronic intraocular pressure elevation impair autoregulatory capacity in streptozotocin-induced diabetic rat retina?
OUTPUT:
