Trans fats are harmful because they raise levels of LDL cholesterol, lower those of the protective HDL cholesterol, increase the level of triglyceride and the level of pro-inflammatory fats.
Transmaščobne kisline so škodljive, ker povišajo raven holesterola LDL, znižajo zaščitni holesterol HDL, povišajo raven trigliceridov in raven maščob, ki povzročajo vnetja.