Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.

Example pair: 
Instruction: Summarize this in about 50 words. 

NBC's late night talk show hosts Jimmy Fallon and Seth Meyers are covering a week of pay for their non-writing staff during the Writers Guild of America strike, which has disrupted production for many shows and movies as Hollywood's writers hit the picket lines this week.

Staff and crew for Fallon's The Tonight Show and Meyers' Late Night are getting three weeks of pay — with the nightly show hosts covering the third week themselves — and health care coverage through September, according to Sarah Kobos, a staff member at The Tonight Show, and a source close to the show.

Kobos told NPR that after the WGA strike was announced, there was a period of confusion and concern among non-writing staff over their livelihoods for the duration.
Response: The WGA strike causes non-writing staff to be concerned about their pay since productions are disrupted. Staff and crew for The Tonight Show and Late Night are getting three weeks of pay, with Jimmy Fallon and Seth Meyers covering their pay during the third week. Employees will have healthcare coverage through September. 

Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context. 

Store the generated pairs in valid JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance: 

{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]} 

Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.

Summarize the significance of the discovery of penicillin in about 50 words.
user
The discovery of penicillin by Alexander Fleming in 1928 revolutionized medicine, leading to effective treatments for bacterial infections. This antibiotic saved countless lives, reduced the impact of infectious diseases, and paved the way for the development of other life-saving antibiotics.
assistant