a method of and system for the treatment of periodontal diseases is disclosed wherein a patient , using a delivery device , applies a medicament directly to the infected site . the delivery device may comprise a piece of tufted dental floss , an interdental brush , a syringe , or a night time application tray for forcibly applying medicament to the infected site . the delivery device carries a supply of an antimicrobial or antibiotic medicament , preferably a tetracycline , dichloride or hydrogen peroxide solution or gel . by flossing , brushing , injecting , or by forcibly disbursing the medicament with the delivery device , the patient can apply the medicament directly on or in close proximity to the infected site . the medicament bonds with the bony structure to promote bone regeneration , decrease osteoclastic activity and to allow osteoblastic activity to continue with a consequent decrease in bone loss rate while promoting bone growth . through the use of an oxygenation agent , fluoride , dichloride , or other medicaments , microbial activity , plaque development , and pathologic processes are decreased .