a compound of the formula : where ; r 1 is o , s ; r 2 is a nitrogen - containing heterocycle ; r 3 is h , c 1 - c 3 alkyl ; x is — n - d - m —; d is a bond , — nr 9 —, — o —, — s —, — s — or — s 2 —; n and m are independently 0 , 1 or 2 , r 8 and r 8 ′ are independently h , c 1 - c 3 alkyl , haloc 1 - c 3 alkyl , hydroxy , or r 8 and r 8 ′ together with their adjacent c atom is — c —; r 9 is independently h , c 1 - c 3 alkyl ; e is ch 2 —, — choh —, — c —, — nr 9 —, — o —, — s —, — s 2 —; n and m are independently 0 , 1 or 2 ; p and q are independently 0 , 1 or 2 , where p + q ≦ 2 ; r 10 is an optionally substituted carbocycle or heterocycle ; r 11 is independently h , c 1 - c 3 alkyl , halo substituted c 1 - c 3 alkyl , hydroxy ; have utility as hiv antivirals .