a method of inhibiting postoperative adhesion severity of mammalian tissues . the method includes the application on an operated tissue surface of an effective therapeutic amount of a pharmaceutical composition containing a pharmaceutically acceptable amount of growth factors and sterilized carboxymethylchitosan . a method of inhibiting postoperative adhesion severity that includes the step of applying a composition comprising a growth factor , where the growth factor is used as a modulating factor on mesothelial cell proliferation is also provided .