disclosed are compounds of the formula : where r 1 , r 2 , r 3 , r 4 , r 5 , r 6 , and x are defined herein . these compounds are selective modulators of npy1 receptors . these compounds are useful in the treatment of a number of cns disorders , metabolic disorders , and peripheral disorders , particularly eating disorders and hypertension . methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided . compounds of the invention are also useful as probes for the localization of npy1 receptors and as standards in assays for npy1 receptor binding . methods of using the compounds in receptor localization studies are given .