red blood cell membrane derived microparticles are safe , economical , effective hemostatic agents in the treatment of a wide range of bleeding conditions and can be considered as universal hemostatic agents . rmp are produced from red blood cells using a high - pressure extrusion membrane shear process and can be lyophilized after production and retain activity even when stored at room temperature . rmp can be administered to original donors , thus avoiding transfusion complications , or can be administered to blood type compatible recipients . rmp produced from type o , rh negative red cells can be given to any person regardless of blood type . rmp can be administered to reduce excessive bleeding resulting from trauma , surgeries , invasive procedures and various bleeding disorders such as platelet disorders , either congenital or acquired , and coagulation disorders , either congenital or acquired .