a c - terminal pilin peptide vaccine for immunizing or treating a patient for infection by a pseudomonas aeruginosa infection is disclosed . the peptide comprises the peptide identified as seq id nos . 3 - 6 ; and a carrier protein conjugated to the peptide . also disclosed is a pilin peptide c - terminal pa pilin peptide having the amino acid sequence identified as seq id no : 3 , and analogs thereof having one of residues t , k , or a at position 130 , d , t , or n at position 132 , q , a , or v at position 133 , e , p , n , or a at position 135 , q , m , or k at position 136 , and i , t , l , or r at position 138 , excluding seq id nos : 1 , 2 , 9 , 10 , and 11 , and the ability to cross - react with antibodies against the corresponding c - terminal peptides from pa strains pak and pao .