according to one aspect of the present invention , there is provided a crystalline hydrochloride salt of darunavir . crystalline hydrochloride salt of darunavir which is characterized by peaks in the powder x - ray diffraction spectrum having 2θ angle positions at about 6 . 7 , 8 . 0 , 13 . 1 , 13 . 9 , 14 . 9 , 19 . 6 , 19 . 9 , 24 . 5 and 27 . 9 ± 0 . 2 degrees . the powdered x - ray diffractogram ( pxrd ) of crystalline hydrochloride salt of darunavir is shown in fig1 . according to another aspect of the present invention , there is provided a process for the preparation of crystalline hydrochloride salt of darunavir , which comprises : a ) providing a solution of darunavir in a solvent ; b ) adding hydrochloric acid to the solution obtained in step ( a ); c ) slurrying the reaction mass obtained in step ( b ) at below 40 ° c . ; and d ) isolating crystalline hydrochloride salt of darunavir . the solvent used in step ( a ) may preferably be a solvent or mixture of solvents selected from the group consisting of water ; a halogenated hydrocarbon solvents such as dichloromethane , chloroform , carbontetrachloride and ethylene dichloride ; an ester solvents such as ethyl acetate , methyl acetate , isopropyl acetate , tert - butyl methyl acetate and ethyl formate ; a ketonic solvents such as acetone , methyl ethyl ketone , methyl isobutyl ketone and diethyl ketone ; an ether solvents such as tetrahydrofuran , 1 , 4 - dioxane , methyl tert - butyl ether , diisopropyl ether and diethyl ether . more preferable solvent is water , dichloromethane , ethyl acetate , methyl isobutyl ketone , methyl tert - butyl ether and diisopropyl ether . darunavir used in step ( a ) may be darunavir in any solvated or hydrated or anhydrous form and preferably the darunavir is darunavir c 5 - c 8 alcohol solvate such as 2 - methyl - 2 - butanol solvate or n - pentanol solvate , darunavir ethanolate and anhydrous form of darunavir . hydrochloric acid can be used in step ( b ) as an aqueous hydrochloric acid or anhydrous hydrochloric acid and preferably aqueous hydrochloric acid is used . preferably the slurrying may be carried out at room temperature for at least 30 minutes . the isolation of crystalline hydrochloride salt of darunavir in step ( d ) may preferably be performed by conventional techniques such as centrifugation and filtration . according to another aspect of the present invention , there is provided a pharmaceutical composition which comprises crystalline hydrochloride salt of darunavir and pharmaceutically acceptable carriers , diluents or excipients and optionally other therapeutic ingredients . the salt may preferable be conveniently formulated into tablets , capsules , suspensions , dispersions , injectables and other pharmaceutical forms . according to another aspect of the present invention , there is provided a process for the preparation of darunavir amorphous form , which comprises : a ) dissolving darunavir or pharmaceutical acceptable salts in a solvent and water ; b ) adjusting the ph of the reaction mass to about 7 . 0 to 8 . 5 with a base ; c ) removing the solvent from the solution obtained in step ( b ) to obtain a residual mass ; d ) slurrying the residual mass obtained in step ( b ) with aliphatic hydrocarbon solvent or aromatic solvent ; and e ) isolating darunavir amorphous form . darunavir or its pharmaceutical acceptable salts used in step ( a ) is crystalline hydrochloride salt of darunavir . the solvent used in step ( a ) may preferably be a solvent or mixture of solvents selected from the group consisting of a halogenated hydrocarbon solvents such as dichloromethane , chloroform , carbontetrachloride and ethylene dichloride ; an ester solvents such as ethyl acetate , methyl acetate , isopropyl acetate , tert - butyl methyl acetate and ethyl formate ; a ketonic solvents such as acetone , methyl ethyl ketone , methyl isobutyl ketone and diethyl ketone ; an ether solvents such as tetrahydrofuran , 1 , 4 - dioxane , methyl tert - butyl ether , diisopropyl ether and diethyl ether . more preferable solvent is dichloromethane , ethyl acetate , methyl isobutyl ketone , methyl tert - butyl ether and diisopropyl ether . preferably the ph of the reaction mass in step ( b ) may be adjusted to 7 . 2 - 8 . 2 and more preferably the ph adjusted to 7 . 5 - 8 . 0 . the base used in step ( b ) may preferably be an organic base or an inorganic base selected from ammonium , sodium hydroxide and potassium hydroxide , and more preferably the base is ammonia . removal of the solvent may be carried out in step ( c ) at atmospheric pressure or at reduced pressure . removal of the solvent may preferably be carried out until the solvent is almost completely distilled off . the aliphatic hydrocarbon solvent or aromatic solvent used in step ( d ) may preferably be a solvent or a mixture of solvents selected from cyclohexane , hexane , n - heptane , toluene and xylene . more preferable aliphatic hydrocarbon solvent is cyclohexane . the isolation of darunavir amorphous form in step ( e ) may preferably be performed by conventional techniques such as centrifugation and filtration . according to another aspect of the present invention , there is provided a pharmaceutical composition comprising a darunavir amorphous form and a pharmaceutically acceptable excipient . the pharmaceutically acceptable inert carrier which can be used may be a solid dosage forms . the solid dosage forms for oral administration may include capsules , tablets , pills , powders and granules . the invention will now be further described by the following examples , which are illustrative rather than limiting . to a mixture of ( 3r , 3as , 6ar )- hexahydrofuro [ 2 , 3 - b ] furan - 3 - ol ( 66 gm ) and acetonitrile ( 300 ml ) was added disuccinimidyl carbonate ( 110 gm ) at 25 to 30 ° c . the reaction mass was cooled to 10 ° c . under nitrogen atmosphere and then added pyridine ( 93 gm ) for 30 minutes . the temperature of the reaction mass was raised to 30 ° c . and stirred for 1 hour 30 minutes at 30 ° c . the reaction mass further cooled to − 10 ° c . under nitrogen atmosphere . a solution of 4 - amino - n -(( 2r , 3s )- 3 - amino - 2 - hydroxy - 4 - phenylbutyl )- n -( isobutyl ) benzene sulfonamide ( 135 gm ) in acetonitrile ( 330 ml ) was added to the reaction mass at − 10 to − 15 ° c . for 45 minutes . to the reaction mass was added triethylamine ( 39 gm ) and monomethylamine ( 5 . 8 gm ) at − 10 ° c ., and the temperature was slowly raised to 20 to 25 ° c . and stirred for 1 hour . the reaction mass distilled off the solvent completely removed under vacuum at below 50 ° c . to obtain a residue . to the residue was added dichloromethane ( 1000 ml ). the dichloromethane layer was washed with 10 % sodium bicarbonate ( 500 ml ), 2 % sulfuric acid ( 500 ml ), 10 % sodium sulfate ( 500 ml ) and 10 % sodium chloride solution ( 500 ml ). the layer was treated with carbon and then added concentrated hydrochloric acid ( 40 ml ). the reaction mass was stirred for 1 hour at 25 to 30 ° c . and filtered . the solid obtained was dried under vacuum at 60 to 65 ° c . for 6 hours to obtain 140 gm of crystalline hydrochloride salt of darunavir . darunavir 2 - methyl - 2 - butanol solvate ( 100 gm ) was dissolved in dichloromethane ( 1000 ml ) and stirred to obtain a solution . to the solution was added concentrated hydrochloric acid ( 30 ml ) and stirred for 1 hour at 25 to 30 ° c . the separated solid was filtered and dried under vacuum at 60 to 65 ° c . for 6 hours to obtain 97 gm of crystalline hydrochloride salt of darunavir . darunavir n - pentanol solvate ( 50 gm ) was dissolved in dichloromethane ( 500 ml ) and water ( 50 ml ) under stirring . to the solution was added concentrated hydrochloric acid ( 20 ml ) and stirred for 1 hour at 25 to 30 ° c . the separated solid was filtered and dried under vacuum at 60 to 65 ° c . for 6 hours to obtain 45 gm of crystalline hydrochloride salt of darunavir . darunavir ( 10 gm ) was dissolved in dichloromethane ( 100 ml ) and stirred to obtain a solution . to the solution was added concentrated hydrochloric acid ( 3 ml ) and stirred for 1 hour at 25 to 30 ° c . the separated solid was filtered and dried under vacuum at 60 to 65 ° c . for 6 hours to obtain 9 . 8 gm of crystalline hydrochloride salt of darunavir . darunavir ethanolate ( 100 gm ) was dissolved in ethyl acetate ( 1000 ml ) and stirred to obtain a solution . to the solution was added concentrated hydrochloric acid ( 30 ml ) and stirred for 1 hour at 25 to 30 ° c . the separated solid was filtered and dried under vacuum at 60 to 65 ° c . for 6 hours to obtain 95 gm of crystalline hydrochloride salt of darunavir . example 4 was repeated using ethyl acetate solvent instead of dichloromethane solvent to obtain crystalline hydrochloride salt of darunavir . example 4 was repeated using methyl tert - butyl ether solvent instead of dichloromethane solvent to obtain crystalline hydrochloride salt of darunavir . example 4 was repeated using methyl isobutyl ketone solvent instead of dichloromethane solvent to obtain crystalline hydrochloride salt of darunavir . example 4 was repeated using diisopropyl ether solvent instead of dichloromethane solvent to obtain crystalline hydrochloride salt of darunavir . crystalline hydrochloride salt of darunavir ( 135 gm ) as obtained in example 1 was dissolved in dichloromethane ( 1200 ml ) and water ( 1000 ml ) at room temperature . the ph of the reaction mass was adjusted to 7 . 5 to 8 . 0 with ammonium solution and stirred for 20 minutes . the organic layer was treated with carbon and distilled off the solvent completely under vacuum at 45 ° c . to obtain foam like residue . cyclohexane ( 1000 ml ) was added to the residue , distilled off the solvent completely under vacuum at 45 ° c . to obtain residue . to the residue was added cyclohexane ( 100 ml ) and stirred for 4 hours at 20 to 25 ° c . the separated solid was filtered and dried under vacuum at 50 ° c . for 12 hours to obtain 120 gm of darunavir amorphous form . crystalline hydrochloride salt of darunavir ( 5 gm ) was dissolved in ethyl acetate ( 50 ml ) and water ( 50 ml ) at room temperature . the ph of the reaction mass was adjusted to 7 . 5 to 8 . 0 with ammonium solution and stirred for 20 minutes . the organic layer was treated with carbon and distilled off the solvent under vacuum at 45 ° c . to obtain foam like residue . cyclohexane ( 25 ml ) was added to the residue , distilled off the solvent completely under vacuum at 45 ° c . to obtain a residue . to the residue was added cyclohexane ( 50 ml ) and stirred for 5 hours at 25 to 30 ° c ., filtered . the solid obtained was dried under vacuum at 50 ° c . for 12 hours to obtain 4 . 2 gm of darunavir amorphous form . example 10 was repeated using methyl tert - butyl ether solvent instead of dichloromethane solvent to obtain darunavir amorphous form . example 10 was repeated using methyl isobutyl ketone solvent instead of dichloromethane solvent to obtain darunavir amorphous form .