the invention may be put into practice in various ways and a number of specific embodiments will be described to illustrate the invention with reference to the accompanying examples : purpose : to prepare a &# 34 ; pearl - drops &# 34 ; toothpaste like product containing h 2 o 2 . this was a composition prepared for consistency but contains no fluoride or flavor . ______________________________________formula % w / w______________________________________hydrogen peroxide ( 20 %) 20 . 00pluronic f127 - poloxamer 15 . 00carbopol 934p ( 5 % w / w ) - carboxypolymethyleme 6 . 50triethanolamine ( 10 % w / w ) 3 . 25deionized h . sub . 2 o , filtered 55 . 25total 100 . 00______________________________________ method : ( 1 ) mixed h 2 o 2 , pluronic , and h 2 o . placed in freezer overnight , then mixed well ; ( 2 ) added carbopol solution and mixed until no globules were seen ; and ( 3 ) mixed in triethanolamine . result : a clear , colorless viscous solution was obtained that when squeezed from a bottle onto a toothbrush , tended to remain on top sinking into bristles , only slowly . purpose : to determine proper carbopol concentration for a dentifrice containing naf ( i . e ., reduces visc . of carbopol gels ). ______________________________________formula a b c d______________________________________hydrogen peroxide ( 20 %) 20 . 0 20 . 0 20 . 0 20 . 0pluronic f127 15 . 0 15 . 0 15 . 0 15 . 0carbopol 934p 1 . 5 1 . 25 1 . 0 . 75triethanolamine ( 10 %) 15 . 0 12 . 5 10 . 0 7 . 5naf 0 . 2 0 . 2 0 . 2 0 . 2water , di filtered 48 . 3 51 . 05 53 . 80 56 . 55total 100 . 00 100 . 00 100 . 00 100 . 00______________________________________ method : ( 1 ) dissolve carbopol in water and h 2 o 2 ; ( 2 ) disperse pluronic f127 in step one and put in freezer overnight ; ( 3 ) thaw and mix well ( some globules remain or may be carbopol salting out ; ( 4 ) add naf ; and ( 5 ) add triethanolamine . ______________________________________re - spindle appearancesults ph speed visc on brush______________________________________a 5 . 76 ta & amp ; tb @ 5 31 , 400 cps too thickb 5 . 83 ta & amp ; tb @ 5 18 , 280 acceptablec 5 . 53 ta @ 5 & amp ; 9 , 960 too thin tb @ 5d 5 . 58 ta @ 5 & amp ; 4 , 270 too thin # 3 @ 10______________________________________ ______________________________________formula % w / w lot______________________________________h . sub . 2 o . sub . 2 ( 20 %) 20 . 0 100pluronic f127 15 . 0 75carbopol 934p 1 . 2 6triethanolamine ( 10 %) 12 . 0 60naf 0 . 2 1water , di filtered 51 . 6 258total 00 . 0 500______________________________________ method : ( 1 ) dissolve carbopol in h 2 o 2 and 75 % of water ; ( 2 ) dissolve naf in remaining h 2 o and add to step 1 ; ( 3 ) pass pluronic through a # 16 screen an disperse in step 2 . place in freezer for one hour ; and ( 4 ) mix above well and add triethanolamine solution . result : a viscous , clear , colorless gel with many air bubbles . ph -- 5 . 43 , viscosity -- 21 , 800 cps ( ta , s -- 5 , r -- 54 . 5 ) the gel dispenses easily from a gly - oxide bottle and stays on a brush like pearl drops toothpaste . ______________________________________formula % w / w lot______________________________________h . sub . 2 o . sub . 2 , 20 % 20 . 0 180 gpluronic f127 28 . 0 252citric acid , anhydrous 0 . 5 4 . 5na citrate , dihydrate 0 . 25 2 . 25naf 0 . 2 1 . 8glycerine 10 . 0 90 . 0na saccharin 0 . 2 1 . 8methyl paraben 0 . 05 0 . 45aromalok 180816 sample flavor 2 . 0 18 . 0water di , filtered 38 . 8 349 . 2total 100 900______________________________________ method : ( 1 ) dissolve citric acid , na citrate , naf , na saccharin and methyl paraben in the h 2 o 2 , water , and glycerine ; ( 2 ) dispense aromalok and pluronic ; ( 3 ) place in freezer ; and ( 4 ) remove from freezer and mix well then package in tubes . ______________________________________formula a b c d e f______________________________________urea 6 . 83h . sub . 2 o . sub . 2 , 35 % 11 . 5pluronic f127 25 . 0citric acid , 0 . 5 s a m eanhydroussodium citrate , 1 . 5dihyroussodium fluoride -- 0 . 2 -- 0 . 2 -- -- stannous fluoride -- -- -- -- 0 . 4 0 . 4water , di filtered qs qs qs qs qs qstotal 100 100 100 100 100 100______________________________________ method : ( prepare 400 g ea . ): ( 1 ) dissolve citric acid , sodium citrate , and urea in water ; ( 2 ) mix with darco g - 60 ( urea containing formulas only at 2 g / l .) and filter thru whatman # 40 filter paper ; ( 3 ) dissolve fluoride , if called for above , mix in pluronic and freeze overnight ; ( 4 ) thaw , add h 2 o 2 ; and ( 5 ) determined initial ph and placed on test at r . t ., 37 ° c . and 45 ° c . tested weekly for 2 months . ______________________________________a - ph 5 . 15 d - ph 5 . 02b - ph 5 . 15 e - ph 4 . 80c - ph 4 . 95 f - ph 4 . 72______________________________________ purpose : to prepare and test the stability of colored gly - oxide dentifrice gels . __________________________________________________________________________formula % w / w a b c d e f g h i__________________________________________________________________________urea 6 . 83h . sub . 2 o . sub . 2 4 . 00pluronic f127 25 . 00citric acid , 0 . 50anhy . sodium citrate , 1 . 50dihy . sodium fluorid 0 . 20fdc yellow # 6 -- . 0007 . 003 . 003fdc red # 40 -- . 003fdc red # 3 -- . 003 . 003 . 003fdc blue # 1 -- . 02 . 003fdc green # 3 -- . 003water di qs qs qs qs qs qs qs qstotal 100 100 100 100 100 100 100 100 100ph 5 . 3 5 . 2 5 . 2 5 . 2 5 . 2 5 . 2 5 . 2 5 . 2 5 . 2__________________________________________________________________________ method : ( 1 ) dissolve citric acid , na citrate , and urea in water ; ( 2 ) mix c darco g60 urea ( 2g / liter ) for 15 minutes ; ( 3 ) suction filter through # 40 whatman ; ( 4 ) dissolve naf and disperse pluronic ; put in freezer ; ( 5 ) thaw , add h 2 o 2 and color ( as an h 2 o conc ). packaged in clear glass jars . placed on physical stability test at r . t ., 37 ° c ., and 45 ° c . conducted a 72 hour light test . compared colors to a 5 ° c . sample . ______________________________________formula % w / w batch______________________________________h . sub . 2 o . sub . 2 11 . 5 575citric acid , anhy . 0 . 5 25sodium citrate , dihy . 1 . 5 75pluronic f127 25 . 0 1250naf 0 . 2 10 . 0flavor - see below 1 . 25 62 . 5sodium saccharin 0 . 2 10 . 0water di , filtered 60 . 5 3002 . 5total 100 . 0 100 . 0______________________________________ method : ( 1 ) dissolve citric acid and sodium citrate , and naf in the water ( also add na saccharin ); ( 2 ) disperse the pluronic f127 and place in freezer overnight ; ( 3 ) when the pluronic is dissolved , add the h 2 o 2 , mix well and divide into eight 592 . 5g sublots ; ( 4 ) add 7 . 5g of each individual flavor to sublots and mix well ; ( 5 ) package in glaminate tubes ( 30 - 40g / tube ); ( 6 ) place on test at r . t ., 37 ° c . & amp ; 45 ° c . ; and ( 7 ) test flavor stability weekly for four months . a . some rt samples swollen and some exude product when opened . tubes were very full . ______________________________________formula % w / w batch______________________________________hydrogen peroxide , 35 % 11 . 5 230 gcitric acid , anhy . 0 . 5 10sodium citrate , dihy . 1 . 5 30pluronic f127 25 . 0 500sodium fluoride 0 . 2 4sodium saccharin 0 . 2 4water , di , filtered 61 . 1 1222total 100 . 0 2000______________________________________method : ( 1 ) prepare the following solution : citric acid 12 . 5 g pass throughnacitrate 37 . 5 a 0 . 2 angstromnaf 5 . 0 filter reservena saccharin 5 . 0 1270 g for usewater , di , filt . 1527 . 5 in step 2 ( below ) total 1587 . 5______________________________________ ( 2 ) charge a beaker with 1270 g of above with mixing and add pluronic . mix in ice both until dissolved ; ( 3 ) add h 2 o 2 and mix well ; ( 4 ) fill into glaminate tubes ; ( 5 ) place on stability test at r . t ., 37 ° c ., 45 ° c ., 55 ° c ., and 65 ° c . ______________________________________formula % w / w batch______________________________________1 . h . sub . 2 o . sub . 2 , 35 % 11 . 5 287 . 52 . citric acid , anhy . 0 . 5 12 . 53 . sodium citrate , dihy . 1 . 5 37 . 54 . pluronic f127 25 . 0 625 . 05 . naf 0 . 2 5 . 06 . na saccharin 0 . 2 5 . 07 . water , di , filtered 61 . 3 1532 . 5total 00 . 0 2500______________________________________ method : ( 1 ) dissolve 2 , 3 , 5 , and 6 in 7 . pass through a 0 . 2 μ millipore filter ; ( 2 ) disperse 4 in above and solubilize by the cold method ; ( 3 ) add h 2 o 2 and mix well ; and ( 4 ) divide into four 1000 ml sub lots . resulting material is identified as example 9 base for use in example 10 . purpose : to prepare gly - oxide dentifrice flavored with menthol , eucalyptol , and gly - oxide flavor . ______________________________________formula a b c d______________________________________ex . 9 base 98 % w / w 97 97 . 5 96 . 5menthol 20 % in ethanol 2 2 2 2gly - oxide flavor 1 1eucalyptol 0 . 5 0 . 5total 100 100 100 100______________________________________ method : ( 1 ) prepare gly - oxide base as shown . see example 9 ; ( 2 ) with mixing , add flavoring ingredients to the base in sequence appearing above ; mix well ; and ( 3 ) fill glaminate tubes c 40 ml each and seal on the vertrod unit . when menthol was added , product changed to a white color but no ppt was seen ( i . e ., particles ). the product has the typical h 2 o 2 flavor . ______________________________________formulaingredients % w / w batch______________________________________1 . h . sub . 2 o . sub . 2 , 35 % 11 . 5 57 . 5 g2 . citric acid , anhy . 0 . 5 2 . 53 . na citrate , dihy . 1 . 5 7 . 54 . pluronic f127 25 . 0 125 . 05 . naf 0 . 2 1 . 06 . xylitol - xylo - pentane - 20 . 0 100 . 0 1 , 2 , 3 , 4 , 5 - pentol7 . h . sub . 2 o , filtered , di 41 . 3 206 . 5total 100 . 0 500 . 0______________________________________ method : ( 1 ) dissolve 2 , 3 , 5 , and 6 in 7 ; ( 2 ) disperse 4 in above and freeze ; ( 3 ) mix well and add 1 ; this was done in an ice bath , and the product was a thick viscous gel at this stage . it is believed the 20 % xylitol acts as a thickener and some pluronic f127 can be removed from the formula __________________________________________________________________________ingredient lot a b c d e f__________________________________________________________________________h . sub . 2 o . sub . 2 , 35 % 11 . 5 w / wcitric acid , anhy . 0 . 5na citrate , dihy . 1 . 5pluronic f 127 25 . 0naf 0 . 2na saccharin 0 . 2felton lime terpenes -- 1 . 25art . felton mint blend -- -- 1 . 00 # 006felton mint blend -- -- -- 1 . 00 # 006agly - oxide flavor -- -- -- -- 1 . 25menthol ( 20 % w / w in -- -- -- -- -- 1 . 00e & amp ; oh ) eucalyptol -- -- -- -- -- 0 . 25water , di , filtered 61 . 1 59 . 85 60 . 1 60 . 1 59 . 85 59 . 85total 100 100 100 100 100 100__________________________________________________________________________ method : ( 1 ) dissolve citric acid , na citrate , na fluoride , and na saccharin in water ( 2 ) disperse pluronic f127 and dissolve by cold method ; ( 3 ) with mixing , add h 2 o 2 and then flavor if called for ; and ( 4 ) after mixing to insure the product to be homogeneous , fill into tubes by hand and seal on a vertrod ( 4h / htv / sp ) dwell @ 7 and heat @ 8 . results : all products were acceptable gels at room temperature . all contained bubbles . purpose : prepare pluronic -- water gels at 23 % and 24 % w / w . determine the viscosity using a brookfield viscometer . ______________________________________sample # 23 % 24 % ______________________________________1 7 , 840 cps 104 , 8002 7 , 840 121 , 8003 10 , 520 112 , 6004 13 , 080 124 , 8005 10 , 040 108 , 000x 9 , 864 114 , 400______________________________________ the temperature of these gels was 21 - 22 ° c . at the time of measurement . the 23 % gels were very viscous but pourable products . the 24 % gels were ringing gels . __________________________________________________________________________ingredients lot a b c d e f__________________________________________________________________________urea - peroxide 20 % sol . 50 % w / w 50 50 50 50 50naf 0 . 2pluronic f127 9997 10 15 20 22 10 10carbopol 93447825 0 . 5natrosol250mr 10220 2 . 5 ( alkali solublecellulose ether ) kh . sub . 2 . sup . p o . sub . 4 . 675naoh 1 . 75glycerine 10methyl paraben . 09propyl paraben . 06na saccharin . 02flavorcolorh . sub . 2 . sup . o qs 28 . 6 23 . 6 18 . 6 16 . 6 28 . 1 26 . 1total 100 100 100 100 100 100__________________________________________________________________________ method : ( 1 ) dissolve parabens in glycerine with heat -- heat to 30 ° c . ; ( 2 ) dissolve naf , kh 2 po 4 , nasac . in h 2 o ( i . e ., h 2 0 in place of urea - peroxide ) @ 5 ° c . keep beaker in ice bath to maintain temp . at 0 - 10 ° c . ; ( 3 ) with mixing add pluronic ; ( 4 ) when dissolved , add carbopol 934 if called for and dissolve with mixing ; ( 5 ) if called for add natrosol 250 m5 to step 1 and slurry ; ( 6 ) with continued mixing ( in ice - bath ) add step 1 or 5 to step 3 or 4 ; ( 7 ) adjust ph to 6 . 0 [ note : with carbopol and natrosol must stabilize before neutralization ]; ( 8 ) bring to weight with h 2 o ; ( 9 ) remove from re - bath and allow to come to rt . results : a and b -- clear solutions , colorless but thin . c and d -- clear , colorless ringing gels of suitable viscosity to use as a dentifrice . taste not unpleasant . e -- product not acceptable . can be made acceptable by buffering . f -- product not acceptable . ______________________________________formula % w / w gm / 1500 gm______________________________________1 . hydrogen peroxide 90 % 4 . 50 67 . 5 gm2 . citric acid , hydrous 0 . 55 8 . 25 gm3 . sodium citrate hydrous 1 . 50 22 . 5 gm4 . pluronic f127 25 . 00 375 . 0 gm5 . sodium fluoride 0 . 20 3 . 0 gm6 . sodium saccharin 0 . 30 4 . 5 gm7 . felton artificial 1 . 25 18 . 75 gm mint blend 0068 . filtered di water 66 . 70 1000 . 0 gmtotal 100 14995 . 0 gm______________________________________ ( c ) thaw to liquid state and add item ( 7 ) with mixing . ______________________________________formula % w / w per 2150 pw______________________________________citric acid , anhydrous 0 . 5 10 . 75 gmsodium citrate , hydrous 1 . 5 32 . 25 gmpluronic f - 127 25 . 0 537 . 50 gmsodium fluoride 0 . 2 4 . 3 gmsodium saccharin 0 . 2 4 . 3 gmglyoxide flavorhydrogen peroxide 35 % 11 . 43 245 . 0 gmdi water 60 . 17 1294 . 0 gmtotal 99 . 0 2128 . 1 gm______________________________________ method : ( 1 ) dissolve citric acid , sodium citrate , sodium fluoride , and saccharin in water ; ( 2 ) disperse pluronic f - 127 in step 1 and dissolve by the cold method ( place in refrigerator overnight and complete solution by mixing the product with the vessel immersed in an ice bath ); ( 3 ) continue mixing and add h 2 o 2 and the flavor if called for ; ( 4 ) fill by hand into 400 . 00 gm jar . table 1______________________________________range of concentrationsingredients % w / w______________________________________urea peroxide 10naf 0 . 2pluronic surfactant 10 - 22 , 18 , 28 , 28 , 25 , 15carbopol 0 . 5 , 6 . 5 , 1 . 2thickening agentnatrosol 2 . 5kh . sub . 2 . sup . p o . sub . 4 ( potassium 0 . 675phosphate ) bufferingagentnaoh ( caustic soda ) 0 . 175 , 0 . 155glycerine 10methyl paraben 0 . 09propyl paraben 0 . 06na saccharine 0 . 2 , 0 . 3h . sub . 2 o 11 . 5 , 16 . 6 , 28 . 6 , 35 . 02 , 10 . 82 - 20 . 77 , 61 . 1 , 55 . 25 , 51 . 6 30 . 8 , 41 . 3 , 63 . 5 , 56 . 3flavors 1 . 25urea 6 . 83h . sub . 2 o . sub . 2 4 , 11 . 5 , 20triethanolamine 12 % ( 0 . 75 , 1 . 0 , 1 . 25 , 1 . 5 ) xylitol 20______________________________________ in an additional embodiment of the invention , from 0 . 5 % to 5 % by weight , sodium lauryl sulfate is added to the above composition to produce a foam dentrifice . the foregoing description merely explains and illustrates the invention and the invention is not limited thereto except insofar as those who have the invention before them are able to make modifications and variations therein without departing from the scope of the invention .