as can be seen in fig1 , the device in the invention includes a first layer in the form of an absorbable polymeric matrix ( 1 ) constituted , in practice , of 100 % collagen . the initial collagen is native bovine dermal collagen , notably from calves , ground and then transformed into a gel before being lyophilized , then crosslinked with glutaraldehyde . the substance formed is in the form of a dry film which can be glued directly onto the reinforced transparent support . preferably , the excess crosslinking agent is eliminated by washing or chemical reduction . as can be seen in fig1 , the reinforced transparent support ( 2 ) includes a textile mesh ( 3 ) constituted of single - strand polyester threads whose texture corresponds to 36 threads and 36 picks per centimeter , while the density is 17 g / m 2 . this textile mesh ( 3 ) is sandwiched between two silicone films ( 4 . 1 , 4 . 2 ), each with a thickness of approximately 100 μm . in practice , the two silicone films are first applied to both surfaces of the textile mesh to form the reinforced transparent support . interlinking of the whole is achieved by cold pressing followed by heat treatment . a silicone glue is then applied by spray or another coating technique to one of the surfaces of this layer , and then the previously prepared collagen matrix is applied . fig2 is a photograph of dermal reconstruction ( just before the epidermal graft ) achieved with the device of the invention ( shown on the right - hand part [ 5 ] of the photograph ) applied to the back of a patient initially burnt to the 3 rd degree and presenting a scar plaque that was excised . the substance was applied directly to the muscle and compared with integra ® drt ( shown on the left - hand part [ 6 ] of the photograph ). in practice , after having excised the rest of the dermis , the surgeon applies the device so that the surface with the collagen is in contact with the muscle . the size of the device is chosen in relation to the size of the burn . once the device has been applied , it is then stapled to the adjacent skin tissue or to another device of the same type . once the dermis has been formed , the device is removed as already explained , by pulling off the reinforced support alone . a fine dermo - epidermal graft is then performed on the regenerated dermis . fig2 represents the dermis reconstructed with the device after three weeks . as can be seen in this photograph , the dermis reconstituted with the integra ® drt device presents granulation tissue growths at the staple points ( 8 ) indicating poor dermal regeneration . these growths are the result of the holes formed by the staples in the integra drt , which expanded during the neodermal formation period . on the other hand , the device of the invention did not tear around the holes formed by the staples , thanks to the presence of the textile mesh in the body of the transparent layer . consequently , the dermis reconstituted with the device of the invention shows no granulation tissue growth at the stapling points ( 7 ). the presence of the textile mesh inside the transparent layer also totally avoids colonization of the textile by the neodermis ; the surface of the neodermis after removal of the transparent layer is therefore smooth and free of bleeding . the transparent layer was able to be removed without any partial excision of the neoformed dermis . the invention and the resulting advantages are made clear in the above description . we can see that the resistance of the device in the invention during the formation of the dermis , thanks to the presence of the open - work mesh in the body of the film , ensured : the absence of contamination ; the lack of formation of granulation tissue at the attachment points ; the absence of excision of the neoformed dermis upon removal of the transparent layer and the textile mesh ; better transparency .