the present invention provides non - peptidic amino derivatives , their therapeutic use as well as pharmaceutical compositions that possess activity as follicle stimulating hormone agonists and are useful in the for treatment of infertility . in particular , the invention provides cyclic and acyclic alpha - and beta - aminocarboxamides , more particularly tetrahydroisoquinolinecarboxamides , piperidinecarboxamides , pyrrolidinecarboxamides , and 2 - amino - 3 - carboxamidopyridine derivatives .