an optical coherence tomography system and method with integrated pressure measurement . in one embodiment the system includes an interferometer including : a wavelength swept laser ; a source arm in communication with the wavelength swept laser ; a reference arm in communication with a reference reflector ; a first photodetector having a signal output ; a detector arm in communication with the first photodetector , a probe interface ; a sample arm in communication with a first optical connector of the probe interface ; an acquisition and display system comprising : an a / d converter having a signal input in communication with the first photodetector signal output and a signal output ; a processor system in communication with the a / d converter signal output ; and a display in communication with the processor system ; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface , wherein the pressure transducer comprises an optical pressure transducer .