the present invention provides a compounds of general formula ixa - d , useful as potential antitumour agents and pharmaceutical composition comprising these compounds exhibits binding affinity with calf thymus dna at a molar ratio of 1 : 5 in aqueous sodium phosphate buffer at ph of 7 . 00 . the present invention further provides a process for the preparation of c2 - fluoro substituted piperazine linked pyrrolo , benzodiazepine of formula .