the present invention provides an isolated lactic acid bacterium , lactobacillus plantarum subsp . plantarum k37 strain , deposited in dsme - deutsche sammlung von mikroorganismen und zellkulturen gmbh under accession no . dsm 27445 . the present invention further provides a pharmaceutical composition comprising the isolated lactic acid bacterium . moreover , the present invention provides a method for preventing or treating a disorder in a subject , comprising a step of administering an effective amount of the isolated lactic acid bacterium to the subject .