the invention relates to a non - invasive method for the diagnosis of cardiovascular disease in a subject , comprising the steps of measuring in a urine sample the concentrations of one or more thromboxanes , the conductivity , and the concentration of at least one additional marker of cardiovascular disease , which marker can be chosen from apolipoprotein , conjugated dienes and lipid peroxides . diagnosing the presence of cardiovascular disease in said subject is carried out by comparison of the analytical results with pre - determined reference values . the invention further relates to a kit for the rapid diagnosis of cardiovascular diseases .