a device for the topical delivery of nitric oxide gas to an infected area of skin includes a source of nitric oxide gas , a bathing unit , a flow control valve , and a vacuum unit . the bathing unit is adapted to surround the area of the infected skin and form a substantially air - tight seal with the skin surface . the bathing unit is also in fluidic communication with the source of nitric oxide . the flow control valve is positioned downstream of the source of nitric oxide and upstream of the bathing unit . the flow control valve controls the amount of nitric oxide gas that is delivered to the bathing unit . the vacuum unit is positioned downstream of the bathing unit and is used to withdraw gas from the bathing unit . application of nitric oxide gas to the infected area of skin reduces pathogen levels in the infected area and promotes the healing process .