the invention relates to the use of olive leaf extracts for producing a pharmaceutical composition capable of inducing angiogenesis and vascularization . in general , the composition can be used for therapeutic applications in order to promote the differentiation of stem cells into endothelial progenitor cells and / or mature endothelial cells , as well as to induce the vessel formation from said endothelial cells . the vascularization - inducing angiogenic composition of the invention is intended for , inter alia , cardiovascular disease , ischemic processes in general , ulcers , and wound healing in both human and veterinary medicine .