the application discloses a good - tasting and palatable gritty drug formulation , wherein the grittiness is associated as a part of a pleasurable organoleptic sensation , which contains a gritty and optionally bad - tasting or odoriferous drug and a seedy fibrous fruit , and optionally an aqueous medium and a gelling agent , and preferably also a sweetener and a flavoring agent , wherein the gritty drug is representatively an antihypercholesterolemic drug , especially a bile acid sequestrant , and particularly cholestyramine , a method for the preparation thereof , and a method of converting a gritty drug into a more readily - acceptable formulation which assists with patient compliance .