the present invention relates to compositions comprising one or more anthraquinones for use in the treatment of obesity and related metabolic and liver disease . more particularly it relates to a plant extract fraction rich in anthraquinones including both anthraquinone glycosides and anthraquinone aglycones obtainable from a member of the leguminosae family , more particularly cassia seeds . it also relates to a method of obtaining a plant extract fraction rich in anthraquinones .