a method for treating psychiatric diseases such as anxiety disorder , affective disorder by neuromodulation of the frontal cerebral cortex , and in particular regions within the orbitofrontal cerebral cortex . the method includes the steps of determining a common group of patients , each suffering from a common specific diagnosis for a psychiatric disorder ; determining which common regions of the patients &# 39 ; orbitofrontal cerebral cortex are involved in the pathogenesis of the abnormal electrical and chemical activity associated with the psychiatric disease ; surgically implanting an electrode and / or catheter and electrical signal generating device and / or drug - delivery pump such that the electrode and / or catheter is positioned within the region of the frontal cerebral cortex known as the orbitofrontal cortex ; and selectively adjusting the level of electrical and / or chemical stimulation in accordance with the specific effect of the stimulation of the patient . in particular , the region of the frontal cerebral cortex most frequently associated with psychiatric disorders is the orbitofrontal cortex .