a surgical tool system . various embodiments of the surgical tool system may comprise surgical instrument that has a handle assembly that operably supports a drive system therein for generating drive motions upon actuation of a movable handle portion operably coupled to the handle assembly . an elongated body protrudes from the handle assembly and operably supports a control rod therein that interfaces with the drive system . the surgical tool system further includes at least two surgical tools selected from the group of surgical tools consisting of : manipulators , nippers , scissors , endocutters , tissue thickness measurement devices , staple appliers , clip appliers , syringes for applying glue , sealant , drugs or medicaments and cauterization devices wherein each of the surgical tool within the group of surgical tools at least has a housing that is removably couplable to the elongated body and a drive assembly that is removably couplable to the control rod for receiving the drive motions therefrom .