compounds of formula wherein r is a c 6 - c 12 substituted or unsubstituted aryl , a c 6 - c 12 substituted or unsubstituted heteroaryl , a c 1 - c 6 substituted or unsubstituted alkyl or — nr ′ r ′, q is c , o , nr ′, s , s 2 , c 2 p y is c , o , nr ′, s , s 2 , c 2 p z is h or c 1 - c 4 alkyl , r ′ is h , c , s 2 , c 2 , a c 6 - c 12 substituted or unsubstituted aryl , a c 6 - c 12 substituted or unsubstituted heteroaryl or a c 1 - c 6 substituted or unsubstituted alkyl , when substituted , aryl , heteroaryl and alkyl are substituted with halogen , c 6 - c 12 heteroaryl , — nr ′ r ′ or cooz , which have diagnostic and therapeutic properties , such as the treatment and management of prostate cancer and other diseases related to naaladase inhibition . radiolabels can be incorporated into the structure through a variety of prosthetic groups attached at the x amino acid side chain via a carbon or hetero atom linkage .