a process for obtaining an angiogenesis inhibitor and an angiogenesis activator from shark cartilage comprising , as the key step , the aqueous extraction of dried shark cartilage . the angiogenesis inhibitor obtained is more potent than shark cartilage not subjected to the extraction step . the angiogenesis inhibitor is particularly useful for the prevention or treatment of cancer . the angiogenesis activator is particularly useful for stimulating wound healing .