an interventional medical device and manufacturing method thereof . the interventional medical device comprises : a stent body ; a surface of the stent body being provided with a drug releasing structure , and drug in the drug releasing structure being drug for suppressing proliferation of adventitial fibroblasts and a drug for suppressing proliferation of intimal and / or smooth muscle cells . in use , after interventional medical device is implanted into a human body , the drug for suppressing proliferation of adventitial fibroblasts carried thereon can promote the compensatory expansion of the vessel , and the drug for suppressing proliferation of intimal cells and / or smooth muscle cells carried thereon can suppress intimal proliferation of the vessel . the combination of the two kinds of drugs greatly reduces the occurrence rate of in - stent restenosis .