the invention concerns a nebuliser with nanometric flow rate of a liquid effluent in a nebulising gas comprising at least arranged substantially concentric , a capillary tube for intake of the liquid effluent and a nebulising needle including a central channel fed with liquid effluent through the capillary tube , a chamber for intake of the nebulising gas feeding a nozzle for expelling the nebulising gas , the nebulising needle passing through the intake chamber and the nozzle expelling the nebulising gas , the nebulising needle including a outlet for the liquid effluent whereof the aperture diameter is less than 20 ? m , the ratio of the diameter of the outlet of the nozzle expelling the nebulising gas and the outlet of the nebulising needle being more than 10 the inventive nanometric flow rate nebuliser and nebulising installation are applicable in mass spectrometry of trace elements contained in intracellular or microbiological medium for example .