according to one aspect of the present disclosure , a control - engaged electrode - driving method for droplet actuation is provided . the method includes , a first voltage is provided to a first electrode for licking off a droplet . a second voltage is naturally discharged to a third voltage for maintaining a droplet movement . a fourth voltage is provided to the first electrode for accelerating the droplet . naturally discharging from the second voltage to the third voltage and providing the fourth voltage to the first electrode are repeated . the first voltage is provided to a second electrode when a centroid of the droplet reaching a centroid of the first electrode . naturally discharging from the second voltage to the third voltage and providing the fourth voltage to the second electrode are repeated .