a novel method of vehicle modulated administration of an anticonvulsive agent to the mucous membranes of humans and animals is disclosed . the vehicle system is an aqueous pharmaceutical carrier comprising an aliphatic alcohol or a glycol , and their combinations with a biological surfactant such as a bile salt or a lecithin . the pharmaceutical composition provides a means to control and promote the rate and extent of transmucosal permeation and absorption of the medicaments via a single and multiple administration . nasal administration of the pharmaceutical preparation produces a high plasma concentration of the anticonvulsant nearly as fast as intravenous administration . such compositions are particularly suitable for a prompt and timely medication of patients in the acute and / or emergency treatment of status epilepticus and other fever - induced seizures