the use of vinyl sulfides , sulfoxides and sulfones in synthetic chemistry for the production of a wide variety of materials is well known . for example , phenyl vinyl sulfides , sulfoxides and sulfones have been used for the synthesis of important heterocycles , in combinatorial chemistry and as diels - alder adducts . although these compounds have been used extensively for a variety of applications , the isotopically labeled versions have not been reported . a simple route for the isotopically labeled production of these important building blocks has been developed .