pdgf - d , a new member of the pdgfvegf family of growth factors , as well as the nucleotide sequence encoding it , methods for producing it , antibodies and other antagonists to it , transfected and transformed host cells expressing it , pharmaceutical compositions containing it , and uses thereof in medical and diagnostic applications , including methods for stimulating growth of a connective tissue or healing a wound in a mammal , which methods comprise administering to the mammal an effective amount of pdgf - d polypeptides or polynucleotides encoding the pdgf - d polypeptides .