phosphate ester compound of hydroxy acid substituted phenyl ester , preparation method and medical use thereof are provided . the title compound is shown in formula , in which y = c 1 - 4 straight carbon chain , m 1 and / or m 2 = h , alkali metal ion , protonated amine or protonated amino acid . the compound has good water solubility and high stability in its aqueous solution , and it can release 2 , 6 - diisopropylphenol rapidly under the action of enzymes in vivo , which has the effects of sedation , hypnosis and / or anesthesia . by protecting hydroxyl of 2 , 6 - diisopropylphenol in compound of formula , the first - pass metabolic activity of 2 , 6 - diisopropylphenol is reduced , so that the synthetic compound can be used for sedation , hypnosis and / or anesthesia .