a latching microregulator for regulating liquid flow on micro - scale levels comprises a substrate having an inlet port and an outlet port , a valve element defining a valve chamber for opening and closing the inlet port , and an actuator assembly for actuating the valve element . the valve chamber is configured to contain a volume of fluid , and the inlet port and the outlet port are in fluid communication with the valve chamber to provide a liquid flow path through the chamber . the actuator assembly comprises a cantilever beam for moving the valve element between an open position and a closed position , an actuator , such as a piezoelectric element , for moving the cantilever beam , and a latch , such as a permanent magnet , for securing the cantilever beam in the closed position . a flow regulation system comprises a plurality of fluid channels of varied flow conductance and a plurality of latching microregulators for selectively blocking or allowing flow through each of the fluid channels .