the present invention comprises the design , synthesis and development of a new class of chemotherapeutic agents for prophylactic and therapeutic treatments in a mammal , particularly a human , believed to be at risk of suffering from a hormone - responsive disorde . in an embodiment of the invention , such treatments include therapeutic compositions comprising novel steroidal antiestrogen and antiandrogen compounds . in a preferred embodiment , such a novel compound of the present invention has an address and a message component , which are made into a single composite entity for more aggressive intervention and effective treatment of hormone - responsive disorders , thereby prolonging the disease - free interval for the patient and reducing a number of side effects .