systems and methods for imaging an imprinted substrate on a printing press is provided . one method comprises sensing light reflected by the substrate using a contact image sensor to produce data representative of the imprinted substrate . the substrate has been imprinted with different colors at a plurality of printing units of the printing press . each printing unit comprises a plate cylinder . the data representative of the imprinted substrate is output by the contact image sensor as analog voltage signals . the method further comprises receiving the analog voltage signals from the contact image sensor at a sensor interface circuit and converting the analog voltage signals to digital signals using an analog - to - digital converter of the sensor interface circuit . the method further comprises processing the digital signals using the sensor interface circuit to produce corrected digital signals and storing data based on the corrected digital signals in a memory .