bradykinin b 1 - receptor antagonists of formula are disclosed . the compounds are useful for treating diseases associated with inappropriate bradykinin receptor activity , such as diabetic vasculopathy , inflammation , pain , hyperalgesia , asthma , rhinitis , septic shock , atherosclerosis and multiple sclerosis . pyrimidines , triazines , and anilines in which q is imidazolyl or pyrrolyl are particularly preferred .