the present invention provides methods for isolating a pha . the method comprises combining the pha , a first solvent and a second solvent to form a combination , the first solvent and the second solvent being capable of forming an azeotrope with the second solvent ; and heating the combination to substantially remove the first solvent from the combination . alternatively , the method comprises combining the pha , a first solvent , a second solvent and a third solvent to form a combination , the first solvent and the second solvent being capable of forming an azeotrope with the third solvent ; and heating the combination to substantially remove the first solvent and the second solvent from the combination .