the invention relates to new 8β - hydrazinomethyl - ergoline derivatives of the general formula , ## str1 ## wherein x y stands for a ## str2 ## or ## str3 ## group , r stands for hydrogen or methyl group , and r 1 stands for hydrogen , a lower acyl group , a di -, ## str4 ## wherein z 1 , z 2 and z 3 each represent hydrogen , halogen or a trifluoromethyl group , or a group of the general formula , ## str5 ## wherein y represents a lower alkyl group , allyl group or phenyl group , and acid addition salts thereof . these compounds possess valuable antiserotonine , antidepressant and hypotensive effects , furthermore they can be applied as starting substances in the preparation of other biologically active ergoline derivatives . the new compounds of the general formula are prepared according to the invention by reacting the respective 6 - methyl - 8β - mesyloxymethyl or - tosyloxymethyl - ergoline derivatives with dry hydrazine . in order to obtain the n - substituted hydrazinomethyl compounds , the n - unsubstituted derivatives are reacted with an acylating agent or with an isothiocyanate .