steroids having the formula ## str1 ## wherein r 1 is hydrogen , acyloxy , halogen or alkoxy of 1 to 10 carbons ; r 2 is halogen or cyano ; r 3 is hydrogen or halogen ; r 4 is carbonyl , β - hydroxymethylene or β - acetyloxymethylene ; and r 5 is hydrogen or fluorine ; can be used as antiinflammatory agents .