pharmaceutical composition of skin respiratory factor , sodium chloride , bicarbonate , fluoride and zinc chloride in a suitable toothpaste vehicle provides effective therapy for gingivitis when brushed on the teeth and gingivae . pharmaceutical composition of srf in a viscous composition suitable for application to the gingivae and effective over an extended period of time for healing tissue damaged by gingevitis . a toothpaste tube for packaging a pharmaceutical composition of srf , sodium chloride , bicarbonate , fluoride and zinc chloride .