the invention includes synthetic immunochemical haptens for the generation of antibodies , the antibodies , and the medical treatment applications for using the antibodies . the antibodies are designed to recognize the common molecular features of d - methamphetamine - like abused stimulants , and will have insignificant cross - reactivity with endogenous substrates or over - the - counter medications . these monoclonal antibodies and their antigen binding fragments are useful in treatment plans for recovering addicts , in emergency room settings for rapidly reversing a drug overdose , in protection of fetuses or fetus from drug - abusing pregnant mothers or in a psychiatric setting to reduce the exacerbation of psychotic disorders caused by stimulant drugs .