a multichamber ampoule with a locking and dispensing mechanism to store several substances and to dispense a mixture consisting of several substances , possessing a multiple - plug closure with several plugs to selectively close and open several outlet openings in the multichamber ampoule , and an adapter for mixing the substances and dispensing the mixture , wherein the multiple - plug closure and the adapter are connected to each other in an assembly designed to be removed from the multichamber ampoule .