the present invention provides a method of producing a 2 - aminonicotinic acid benzyl ester derivative at a high yield and with a high purity . by reacting a benzyl halide derivative with a 2 - aminonicotinic acid derivative in a polar solvent in the presence of a prescribed base , it is possible to obtain a 2 - aminonicotinic acid benzyl ester derivative at a high yield and with a high purity .