a needle core biopsy instrument / extractor for extracting a tissue sample via needle aspiration is disclosed . the extractor comprises a first cannula having a sharpened , beveled cutting tip and biopsy reservoir formed on it distal end . the proximal end of the first cannula is in fluid communication with a conventional syringe such that when the plunger of the syringe is retracted via manipulation o the extractor , a vacuum is created within the biopsy reservoir of the first cannula axially mounted about the first cannula is a second cutting cannula which is designed and configured to selectively cover and uncover the distal end of the first cannula . a biasing member , preferably a spring , is provided to urge the second cannula forward about the distal end of the first cannula . the syringe , coaxially positioned first and second cannulas , and biasing member are contained within an introducer which is preferably designed and configured to be manipulated by one hand . the handle slide and lever of the device are oriented in such a way as to allow the retention of tissue via vacuum and the severing of the specimen by the second cannula to be exactly timed by cam operation .