Exercise as it relates to Disease/Home based exercise to improve quality of life in elderly women with osteoporosis-related vertebral fractures

This is a critique of the research article: Papaioannou A, Adachi J, Winegard K, Ferko N, Parkinson W, Cook R, et al. Efficacy of home-based exercise for improving quality of life among elderly women with symptomatic osteoporosis-related vertebral fractures. Osteoporosis International. 2003;14(8):677-82.
It was written for an assignment in the unit, Health, Disease and Exercise at the University of Canberra.
What is the background to this research?
Osteoporosis is defined as a systemic skeletal disease characterised by low bone mass and microarchitectural deterioration of bone tissue, which leads to increased bone fragility and higher risk of fracture. 
Research into osteoporosis and how the severity of the condition can be alleviated or managed via the use of exercise is crucial as osteoporosis can occur in many populations and ethnic groups, with elderly people being at the greatest risk. Hence, the possible benefits that home-based exercise can have on this disease need to be explored, to help those suffering from the disease and possibly create a cost-effective method of getting treatment.
Where is the research from?
This research article was published in the Journal "International Osteoporosis".
The primary author of this article is Dr. Alexandra Papaioannou. She is a geriatrician and has a special interest in osteoporosis, pharmacology and falls and quality of life in the elderly population. She has been involved with many papers regarding osteoporosis. In addition, many of the other authors have completed research on osteoporosis in some capacity.
What kind of research was this?
This study was a randomized control trial. Two groups were created, an exercise and control group. The exercise group participated in the intervention whereas the control group did not participate in the intervention but were later used for comparison.
Randomized control trials are considered to be the most credible method of finding out whether a cause and effect relationship exists. 
What did the research involve?
The study involved 74 female participants over the age of 60 split randomly into either an exercise or control group. 
All subjects had to meet the following criteria:
In this study, the exercise group had to complete exercises for 60 minutes a day, 3 days a week. Their exercises included stretching, upper and lower body resistance training and aerobics. The control group had no guidelines for exercise and were told to continue with their usual daily activities.
At baseline, 6 months and 12 months, participants had to complete the Osteoporosis Quality of Life Questionnaire (OQLQ), the Sickness Impact Profile (SIP), the Sway Test and the Timed Up and Go Test. At baseline and 12 months participants had to complete a dual-energy X-ray absorptiometry (DEXA) scan assessing bone mineral density (BMD) at the lumbar spine and femoral neck. 
A limitation of the study was that the OQLQ had not been validated, therefore the results might not be of any significance. Also, some of the participants had asymptomatic vertebral fractures, but it was thought that the intervention would be best suited for those with symptomatic fractures. Furthermore, 17 participants failed to complete the study and adherence to the intervention dropped after the first 6 months, this may be attributed to the fact that there was decreased supervision by the therapist after 6 months.
What were the basic results?
6 Months
12 Months
SIP, Timed Up and Go and BMD were noted as not having any significant changes.
The results are consistent with what the researchers concluded. The researchers deducted that over a 6 month period, a home exercise program improved quality of life in symptoms, emotion, leisure and social activities. Furthermore they believed that if home based exercises are completed over 12 months, improvements recorded at 6 months will be sustained.
What conclusions can we take from this research?
Despite not having the largest final group size, this article has put forward evidence that home-based exercises can improve the quality of life in postmenopausal women with osteoporosis-related vertebral fractures. However, the validity of this evidence is negatively impacted due to not using a validated test (OQLQ) and low adherence to the intervention. In saying that the data provided is valuable in showing how quality of life can be improved in this population. The findings in this paper correlate with other research done in this area, in that exercise induces positive effects in women with osteoporosis whether or not they have a vertebral fracture. Nevertheless, more research should be conducted on what exercises prove to be more useful in improving the quality of life and overall health of those suffering from osteoporosis and/or vertebral fractures.
Practical advice.
Increasing home-based exercise in this population will prove beneficial, as seen above. However, as this population is highly susceptible to injury via falls , it would be wise to consult a specialist (i.e exercise physiologist) before participating in any physical activity to check for any contradictions to exercise. Also, regular check-ups or perhaps even monitored exercise would be advantageous in making sure the individual is safe.
Further information/resources.
Osteoporosis Australia
Osteoporosis - An Overview
Exercise Recommendations for Osteoporosis
References.