 <p>Can you supply a dropbox link to one of the images so I can see what you mean? Do you mean you have one scan of 4 images all on the same layer, and you need to crop 4x and resave individual images? Or is each image on its own layer?</p> <p>Are the 100 images all exactly the same layout? If so, you may be able to create an action that would cut down on your time.</p> <p>If the images are on separate layers, you can use File > Scripts > Export Layers to files...</p>