 <p>If I understand correctly, the behavior you want is to drop each of your columns market with class="col" into a row, when your media query for small screens comes into effect.</p> <p>First of all, Outlook will strip out all in-line styling (as you noticed using F12), so best to double that up using the equivalent html attributes for each of your elements. </p> <p>Secondly, max-width is not supported by Outlook (and Lotus Notes 8 &amp; 8.5), so you will need to wrap each of your <code>&lt;table&gt;</code>s that are inside you 'col' columns into conditional code which creates a table with a set width to hold everything in, that targets IE and Microsoft Outlook. You will need to use something like:</p> <pre><code>&lt;!--[if (gte mso 9)|(IE)]&gt; &lt;table width="525" align="left" cellpadding="0" cellspacing="0" border="0"&gt; &lt;tr&gt; &lt;td&gt; &lt;![endif]--&gt; &lt;table style="table-layout: auto; background-color: white; padding-left: 10px; padding-right: 10px;" border="0" cellpadding="0" cellspacing="0" width="100%"&gt; &lt;tbody&gt; &lt;tr&gt; &lt;td style="padding-top: 15px;padding-right: 20px;padding-bottom: 0;padding-left: 20px;font-size: 26px;line-height: 30px;font-weight:400; font-family: Arial, sans-serif; color: #0056a6;" align="left"&gt;&lt;img src="/resources/handlers/dcimage.ashx" style="height: auto; display: inline;" border="0"&gt;,&lt;/td&gt; &lt;/tr&gt; &lt;tr&gt; &lt;td style="padding-top: 15px;padding-right: 20px;padding-bottom: 20px;padding-left: 20px; font-size: 14px; font-weight:normal; line-height: 14px; font-family: Arial, sans-serif; color: #2d353d;" align="left"&gt; LOREM IPSUM &lt;/td&gt; &lt;/tr&gt; &lt;/tbody&gt; &lt;/table&gt; &lt;!--[if (gte mso 9)|(IE)]&gt; &lt;/td&gt; &lt;/tr&gt; &lt;/table&gt; &lt;![endif]--&gt; </code></pre> <p>I would strongly recommend following this <a href="http://webdesign.tutsplus.com/articles/creating-a-simple-responsive-html-email--webdesign-12978" rel="nofollow">guide to build responsive emails that work on all major mail clients</a> for a more in-depth explanation of this, and also other very useful tricks for making email work even on Outlook :)</p>