The man's VW Golf car collided with the articulated lorry at about 19:00 on Monday near Inverkeillor.
The 30-year-old was taken to Ninewells Hospital, where he remains in a critical condition. The lorry driver was uninjured.
Officers are investigating the circumstances of the crash, and have appealed for witnesses.
An Arbroath man has been left in a critical condition after a crash between his car and a lorry on the A92.