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Wigan St Pats' win against Leigh Miners Rangers was broadcast in the first round, watched by 20,000 viewers.
Siddal progressed after beating Milford Marlins 16-4 at home in round one.
Recs meanwhile travelled to Aberdeen Warriors, winning 62-8 against the Scottish side.
"The reaction we got to that first game was phenomenal," BBC rugby league commentator Dave Woods said.
"Some 20,000 viewers tuned in, and our Twitter feed was extremely busy with people saying how much they enjoyed the game.
"People were watching all over the country, and were clearly blown away by how entertaining the game was - standards produced by both Miners and St Pats were outstanding."
Featherstone Lions v Wests Warriors
Haydock v Thornhill
Kells v Rochdale Mayfield
London Chargers v Fryston
Myton Warriors v York Acorn
West Hull v Thatto Heath
Wigan St Pats v Egremont Rangers
Pilkington Recs v Siddal (14:15 GMT)
National Conference League champions Siddal will travel to divisional rivals Pilkington Recs in BBC Sport's live-streamed Challenge Cup second round tie on Saturday, 11 February.