The owners of the Bon Accord Centre want to build new shops, flats and a hotel on land to the north of the shopping complex.
The plans include the creation of a four or five storey retail block, linking the Bon Accord Centre with John Lewis.
Planning permission in principle has been sought.
The plans include demolishing Santander and Co-op buildings on George Street to make way for new shops and a hotel.
Also, a reconfiguration of Crooked Lane which links Harriet Street with St Andrews Street.
The owners of the Bon Accord Centre said the development would create a new retail destination for the area, and would enhance the environment of George Street.
Plans to redevelop part of George Street in Aberdeen have been submitted to the city council.