The charges relate to alleged incidents in High Wycombe, Aylesbury and Wendover between 1998 and 2002.
Mohammed Kayani, 64, from High Wycombe, Berkley John, 75, and Mohammed Aslam, 59, both from Aylesbury, and Saeed Aham, 50, from Luton, are in police custody.
Tariq Hussain, 45, from High Wycombe, has been released on bail.
Mr Kayani, Mr John, Mr Ahmad and Mr Aslam have been charged with a number of sexual offences including conspiracy to rape or indecently assault girls under 16 and women, false imprisonment and allowing premises to be used for unlawful sexual intercourse.
Mr Hussain has been charged with one count of procuring a woman to become a prostitute.
Five men have been charged with a series of historical sex offences in Buckinghamshire.