The 21-year-old local man was in the front seat of a BMW 318 which crashed with another car on the A281 north of Cowfold on Saturday.
He was flown to St George's Hospital in Tooting, south London, where he died from his injuries.
The car crashed with a VW Polo between Cowfold and the A281 junction with Picts Lane.
Three people trapped in the cars were freed by West Sussex Fire and Rescue Service.
The two drivers, both women in their 20s, were taken by ambulance to the Royal Sussex County Hospital, Brighton, with serious injuries.
Sussex Police have renewed their appeal for any witnesses to the crash to come forward.
A passenger in a car which crashed in West Sussex has died in hospital.