It happened on the Knockmore Road at about 14:25 GMT on Wednesday.
The road has been closed at its junction with the Ballinderry Road and police have put diversions in place.
Meanwhile, in Bangor, County Down, a pedestrian was hit by a vehicle on the town's Main Street. She is said to be in a stable condition in hospital.
A cyclist in his 40s has died after his bike was in collision with a lorry in Lisburn, County Antrim.