After plunging more than 12% on Tuesday, shares in Anglo American ended down a further 1.2%.
Anglo had announced a major restructuring plan and said it was suspending its dividend until the end of next year.
Mining shares have been hit by falling commodity prices, with iron ore prices at 10-year lows.
The FTSE 100 index ended the day down 8.5 points at 6,126.6 points.
Glencore rose 4.6%, Rio Tinto was 1.1% higher and BHP Billiton was up 2.4%.
Among the other mining firms, shares in Fresnillo dropped 0.9% after it said a pipeline had burst at its Saucito mine in Mexico. However, the firm said it would not suspend production at the mine.
Shares in equipment hire group Ashtead were the biggest riser, jumping 6.9%, after it said strong demand in the US meant its annual results should now be better than previously forecast.
Analysts had expected Ashtead to report full-year pre-tax profits of £608m for the year to April.
On the FTSE 250, shares in Entertainment One, the owner of the Peppa Pig children's TV character, rebounded 10.7% after the company said it was trading in line with its full-year guidance.
The firm's shares fell 20% on Tuesday after announcing that its refinancing plan would increase monthly interest payments.
Stagecoach shares fell 14.4% after the bus and rail operator cut its full-year profit forecast. The travel group blamed the Paris terror attacks for "discouraging people from travelling to major cities".
On the currency markets, the pound rose 1% against the dollar to $1.5168, and climbed 0.16% against the euro to €1.3804.
(Close): Mining companies regained some of the losses they posted on Tuesday, but Anglo American slid further into the red.