Welsh-owned Silvercrest Group plans to open the 33-bed home in Williamstown, near Tonypandy, in the autumn.
Chief executive Dr Bikram Choudhary said they were recruiting nurses, carers and administration staff.
He said the home would "provide a much needed service in RCT and Taff Ely".
A new £1m dementia care home in Rhondda Cynon Taff will create 50 jobs, the operator has said.