Gareth Hindmarsh, 34, of Tawney Crescent in the city, was charged on Thursday.
Linda Norcup, 46, was found dead in "suspicious" circumstances on Sunday at her Beckett Avenue home at 13:00 BST, police said.
A Home Office post-mortem examination found she had been strangled. Mr Hindmarsh will appear before magistrates on Friday.
A man has been charged with the murder of a woman in Stoke-on-Trent.