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28 August 2015 Last updated at 15:29 BST
The storm caused powerful winds and major flooding which destroyed large parts of the city.
Thousands of people lost their homes, and more than 1,800 were killed.
US President Barack Obama will lead the events to remember those who lost their lives and special services will be held across the weekend.
Watch Hayley's report.
Events are being held across America to mark ten years since Hurricane Katrina devastated the city of New Orleans.