Wayne Letherby, 42, died on 17 April following an attack in De Winton Street, Tonypandy.
Two men have previously appeared in court charged with murder; Jamie Leyshon from Tonypandy and Dean Doggett from Penygraig, both 26, were remanded in custody on Thursday.
The woman was due before Pontypridd Magistrates' Court on Saturday.
A 25-year-old woman has been charged with the murder of a man in Rhondda Cynon Taff.