Ben Calveley, from the Carmel area of Llanerchymedd, died in the collision with a black Nissan Navara on Sunday.
Mr Calveley, who was riding a blue Suzuki motorbike, was pronounced dead at the scene.
His family said: "Ben was killed on a road he knew well, that we all regularly use as a family."
The crash happened on the B5109 between Bodffordd and Llynfaes at around 01:00 BST.
Mr Calveley's parents, Simon and Delyth, sister Clare, younger brother Dion and girlfriend Stephanie said in a statement: "Travelling on that road will always be difficult from now on. We visited the scene today to lay flowers.
"We just can't believe what's happened - it seems so unreal at the moment."
Mr Calveley was a former pupil of Ysgol Corn Hir and Ysgol Gyfun Llangefni. He had recently graduated from Coleg Menai as an apprentice joiner, and was looking forward to starting work.
They added: "We are devastated and numb with shock of losing such a wonderful son. He was such a loving, caring, easy-going young man that would do anything for anyone.
"He was passionate about motorcycles and cars.
"We are in total disbelief at the moment."
No-one in the car was hurt.
North Wales Police are appealing for witnesses.
The family of 19-year-old Anglesey biker who was killed in a collision with a 4x4 car say they are "devastated and numb with shock".