The Twaddell Avenue protest has been ongoing since July 2013.
It began after a Parades Commission determination not to allow a return leg of an Orange parade to pass a section of the Crumlin Road.
In a statement, the Ballysillan lodge said it will continue to apply for an evening parade past the Ardoyne shops.
Released on Friday evening, the statement criticised some of the groups involved in recent attempts to resolve the standoff.
However, it said the lodge had been left with no choice but to suspend the protest.
This does not mean the protest is over.
Two other north Belfast lodges, Ligoniel and the Earl of Erne, who had backed a proposed deal to end the Ardoyne parade dispute, will continue their protest.
The County Grand Orange Lodge of Belfast said it respects the decision by Ballysillan "to suspend their participation in any further protests regarding securing a homeward parade along the Crumlin Road".
However, speaking after a parade on Saturday, the County Grand Master of the Orange Order in Belfast, George Chiddick, insisted the protest will continue until a resolution is found.
That means the protest camp at Twaddell, which was set up in 2013, will remain open.
Sinn FÃ©in MLA Gerry Kelly said any move towards ending nightly protests at Twaddell Avenue was "to be welcomed".
"People in the area will be relieved at any such move," he said.
"Sinn FÃ©in has been consistent in our support of inclusive dialogue involving local communities and parade organisers in order to arrive at a resolution to these issues."
Talks aimed at resolving the dispute involving Ligoniel and the Earl of Erne lodges and a nationalist residents group, the Crumlin Ardoyne Residents Association (CARA), are expected to resume within a matter of weeks.
One of the Orange lodges at the centre of a long-running parading dispute in north Belfast has suspended its protest.