15 October 2015 Last updated at 18:28 BST
Between 2011 and 2014, the five health trusts settled a total of 570 cases.
In many cases, the total amount paid to lawyers and other experts such as architects and accountants dwarfed the settlements to patients.
The fees have been defended by the directorate of legal services who are solicitors for the Health Service.
BBC News NI Health Correspondent Marie-Louise Connolly reports.
Almost £110m has been paid out on medical negligence cases and legal fees in Northern Ireland over a three-year period, figures obtained by the BBC have revealed.