The 90-year-old man was a passenger in a Vauxhall Astra which was in collision with a Honda Jazz at about 12:10 BST on the A591 at Ings.
The man, from Bolton-le-Sands, died at Royal Preston Hospital on Monday morning, Cumbria Police said.
Maureen Runswick, 81 and from Staveley, died at the scene.  She leaves behind two daughters and two grandchildren, who said she will be sorely missed
A 56-year-old man driving the Astra, also from Bolton-le-Sands, is in a serious but stable condition at Royal Preston Hospital.
The road was closed for five hours while emergency services dealt with the incident. Police are appealing for witnesses.
A second person has died after a crash between two cars on Saturday.