18 April 2016 Last updated at 19:57 BST
This constituency also had the closest contest in the last Assembly Election. Just 62 votes decided the final seat.
On the countdown to May's ballot, BBC NI South West reporter Julian Fowler has been on the election trail.
Fermanagh and South Tyrone provided one of the most dramatic results in last year's Westminster election, with Tom Elliott's surprise victory over Michelle Gildernew.