The Uruguyan scored four times and provided three assists as Barcelona revitalised their La Liga title push by thumping Deportivo La Coruna 8-0.
His 30th league goal of the campaign took his overall tally to 49 - matching his best in all competitions for a season, achieved with Ajax in 2009-10.
So how does the former Liverpool forward compare with England's finest?
Suarez has 49 goals this season - the same as Harry Kane and Jamie Vardy combined - but has some way to go to beat Messi's record of 73 set in 2011-12.
Luis Suarez had one of the best nights of his career on Wednesday in what is set to be his most prolific season yet.