which native civilization lived in the region that is now eastern and southern mexico
Indigenous peoples of Mexico The Maya civilization, though also influenced by other Mesoamerican civilizations, developed a vast cultural region in south-east Mexico and northern Central America, while the Zapotec and Mixtec culture dominated the valley of Oaxaca, and the Purépecha in western Mexico.
Alonso Álvarez de Pineda
Navajo Archaeological and historical evidence suggests the Athabaskan ancestors of the Navajos and Apaches entered the Southwest around 1400 CE.[7][8] The Navajo oral tradition is said to retain references of this migration.[citation needed]
Maya civilization The Maya civilization was a Mesoamerican civilization developed by the Maya peoples, and noted for its hieroglyphic script—the only known fully developed writing system of the pre-Columbian Americas—as well as for its art, architecture, mathematics, calendar, and astronomical system. The Maya civilization developed in an area that encompasses southeastern Mexico, all of Guatemala and Belize, and the western portions of Honduras and El Salvador. This region consists of the northern lowlands encompassing the Yucatán Peninsula, and the highlands of the Sierra Madre, running from the Mexican state of Chiapas, across southern Guatemala and onwards into El Salvador, and the southern lowlands of the Pacific littoral plain.