what is the treatment for african sleeping sickness
African trypanosomiasis Prevention of severe disease involves screening the population at risk with blood tests for TbG.[1] Treatment is easier when the disease is detected early and before neurological symptoms occur.[1] Treatment of the first stage is with the medications pentamidine or suramin.[1] Treatment of the second stage involves eflornithine or a combination of nifurtimox and eflornithine for TbG.[2] While melarsoprol works for both stages, it is typically only used for TbR, due to serious side effects.[1] Without treatment it typically results in death.[1]
Scabies Scabies is endemic in many developing countries,[42] where it tends to be particularly problematic in rural and remote areas. In such settings, community-wide control strategies are required to reduce the rate of disease, as treatment of only individuals is ineffective due to the high rate of reinfection. Large-scale mass drug administration strategies may be required where coordinated interventions aim to treat whole communities in one concerted effort.[43] Although such strategies have shown to be able to reduce the burden of scabies in these kinds of communities, debate remains about the best strategy to adopt, including the choice of drug.[43][44]
Bubonic plague Prevention is through public health measures such as not handling dead animals in areas where plague is common.[1] Vaccines have not been found to be very useful for plague prevention.[1] Several antibiotics are effective for treatment including streptomycin, gentamicin, and doxycycline.[3][4] Without treatment it results in the death of 30% to 90% of those infected.[1][3] Death, if it occurs, is typically within ten days.[6] With treatment the risk of death is around 10%.[3] Globally there are about 650 documented cases a year which result in ~120 deaths.[1] The disease is most common in Africa.[1]
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