what is the major advantage of blast over smith-waterman
BLAST The main idea of BLAST is that there are often High-scoring Segment Pairs (HSP) contained in a statistically significant alignment. BLAST searches for high scoring sequence alignments between the query sequence and the existing sequences in the database using a heuristic approach that approximates the Smith-Waterman algorithm. However, the exhaustive Smith-Waterman approach is too slow for searching large genomic databases such as GenBank. Therefore, the BLAST algorithm uses a heuristic approach that is less accurate than the Smith-Waterman algorithm but over 50 times faster. [8] The speed and relatively good accuracy of BLAST are among the key technical innovations of the BLAST programs.
Aubrey Woods Aubrey Harold Woods (9 April 1928 â€“ 7 May 2013)[1][2] was a British actor and singer.
.properties Each parameter is stored as a pair of strings, one storing the name of the parameter (called the key), and the other storing the value.
IEEE 754-1985 The leading 1 bit is omitted since all numbers except zero start with a leading 1; the leading 1 is implicit and doesn't actually need to be stored which gives an extra bit of precision for "free."