Hal ieu dianggap aman dina kuantitas low, tapi teu aya studi cukup geus dilakukeun ngeunaan kuantitas leuwih luhur. Pikeun leuwih inpo, tingali pernyataan ku FDA AS: [https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.530&SearchTerm=disodium%20guanylate]https://www.accessdata.fda.gov/scripts/cdrh/cfcdocs/cfcfr/CFRSearch.cfm?fr=172.530&SearchTerm=disodium%20guanylate) Aya studi nu nunjukkeun efek toksik kumaha oge, tingali contona: [https://www.ncbi.nl.gov/clm/cmc/cmc593/pmc593/pmc593/
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