The substance was heated. The shape of the substance changed. The volume of the substance changed. The substance changed into a new substance.
When a scientist performs an experiment, there are many changes that can occur. Which observation should she list as a chemical change?

Options:
- The substance was heated.
- The shape of the substance changed.
- The volume of the substance changed.
- The substance changed into a new substance.

The substance changed into a new substance.