Studies have shown that to become a man, you need to have at least one Y chromosome. 300 million years ago, the male specific Y chromosome contained 1438 genes at the time of its birth, but now there are only 45. At this rate, the Y chromosome will disappear in about 10 million years. 
In the process of human evolution, we can find methods of parthenogenesis or asexual reproduction, so as to avoid the reproductive risk caused by gene deletion
 with the demise of Y chromosome, mankind will also die out.