Recently, researchers have found that fever can promote the transfer of lymphocytes to the infected site
After Hsp90 binds to integrin, it can activate the signal pathway that promotes T lymphocyte migration.
 They explain that this is because fever increases the expression of heat shock protein 90 (Hsp90) in T lymphocytes, which binds to integrins and promotes T lymphocytes to adhere to blood vessels and eventually accelerate migration to the site of infection