Recently, researchers have found that fever can promote the transfer of lymphocytes to the infected site
Fever can induce Hsp90 to bind to the tail of integrin and activate integrin.
 They explain that this is because fever increases the expression of heat shock protein 90 (Hsp90) in T lymphocytes, which binds to integrins and promotes T lymphocytes to adhere to blood vessels and eventually accelerate migration to the site of infection