The milk of many mammals contains cannabinoids, substances that are known to stimulate certain receptors in the brain  To investigate the function of cannabinoids, researchers injected newborn mice with a chemical that is known to block cannabinoids from reaching their receptors in the brain  The injected mice showed far less interest in feeding than normal newborn mice do
Ttherefore, cannabinoids probably function to stimulate the appetite
The chemical that blocks cannabinoids from stimulating their brain receptors does not independently inhibit the appetite.