Colfax Beta-80 is a rare genetic defect found primarily in people of Scandinavian descent  Over 97% of known carriers of this defect are citizens of, or are direct descendants of immigrants from, Denmark, Norway, and Sweden
People who carry the Colfax Beta-80 defect are at substantially higher risk for contracting Lupus and related autoimmune diseases
A person not of Scandinavian descent born with the Colfax Beta-80 defect is more likely to contract Lupus than is a Scandinavian who is born without this defect.