Recently, researchers have found that fever can promote the transfer of lymphocytes to the infected site
When Hsp90 binds to integrin, it can activate the signal pathway that promotes T lymphocyte migration
 This is because fever increases the expression of heat shock protein 90 (Hsp90) in T lymphocytes, which binds to integrins and promotes T lymphocytes to adhere to blood vessels and eventually accelerate migration to the site of infection, they explained