The researchers announced that they have discovered how certain substances in mice make the brain feel full after eating  Previous studies have found that when mice eat, in the hypothalamic paraventricular nucleus, which is the appetite center, a type called  The protein nesfatin-1 will increase, making mice feel full  But the specific mechanism of how it works has always been a mystery  The researchers removed brain nerve cells from the paraventricular nucleus of mice and labeled some that contained nesfatin-1 Protein cells, and found that this cell can react with high concentrations of glucose and insulin and be activated
After eating carbohydrates such as rice and bread, the concentration of glucose and insulin in the blood of mice will increase
This response is the cause of the brain's feeling of fullness