It is proposed to introduce mosquitoes into the wild with genetic alterations that destroy their diseasecarrying capacity. In this way the dangerous wild population could eventually be replaced by a harmless one without leaving room for another disease-transmitting strain to flourish. One candidate gene would interfere with the mosquitoes' finding mates; another would cause the destruction of a disease parasite before the stage at which it could be transmitted; another would disable the mechanism of the mosquito' s own resistance to disease
that it would die before transmitting the disease.
Evidence is not presented to show that each alternative method has been successfully tested on a limited scale.