Compared with other mass spectrometry techniques, time-of-flight mass spectrometers are easy to operate and can be used even if they are not trained in analytical chemistry  Especially in recent years, with the development of pathogenic microorganism identification and mass spectrometry imaging, it is more and more popular in the field of clinical detection  For example, in the past, microbial identification was done by biochemical culture, which was time-consuming and low accuracy, but now time-of-flight mass spectrometry is used to identify proteome level with high speed, high flux and better accuracy
In addition, the traditional detection and analysis of protein molecules is mostly immune detection, which needs the assistance of third-party antibodies, which is first carried out by the antibody and the detected substance, and then detected by the instrument, the method is complex and easy to cause false positive, while the time-of-flight mass spectrometer can directly detect the molecules of the detected substance
The structure of the instrument is complex.