It is proposed to introduce mosquitoes into the wild with genetic alterations that destroy their diseasecarrying capacity. In this way the dangerous wild population could eventually be replaced by a harmless one without leaving room for another disease-transmitting strain to flourish. One candidate gene would interfere with the mosquitoes' finding mates; another would cause the destruction of a disease parasite before the stage at which it could be transmitted; another would disable the mechanism of the mosquito' s own resistance to disease
that it would die before transmitting the disease.
It does not take into account positive roles that mosquitoes play in the environment, such as serving, in the larval stage, as food for fish.