pseudosarcomatous fibromyxoid tumor of the prostate ( pfmt ) first reported by hafiz et al . in 1984 , is a benign fibroproliferative process that histologically resembles sarcoma .
although these benign fibroproliferative processes of the prostate are unusual , it is important to recognize these lesions in order to avoid unnecessary radical procedures . also the pathologist should use special immunohistochemical stains to verify that it is a benign fibroproliferative process .
a 70-year - old man has nearly a 2-year history of lower urinary tract symptoms ( luts ) such as nocturia , urgency and difficulty in voiding .
due to a high level of prostate specific antigen ( psa ) , prostate biopsy was performed in another urology department .
the psa level was 5.02 ng / ml . the measurement of the prostate volume with pelvic ultrasound was nearly 200 gr .
cystoscopy revealed a normal anterior urethra with a large protruding prostatic mass and normal bladder .
based on these findings , open adenomectomy ( suprapubic prostatectomy ) was performed nearly 2 years ago .
the patient has been followed - up for two years and has no urinary symptoms in this period .
small gland proliferations was observed in the limited periphery place and in this place the reaction with hmw ck and p63 antibodies was seen in the basal cells ( fig .
3 ) . staining in the spindle cells was negative for vimentin and cd 34 .
the overall clinical and pathological features are consistent with pseudosarcomatous fibromyxoid tumor of the prostate .
staining for smooth muscle actin ( original magnification x10 ) . staining for p63 in the basal cell ( original magnification x10 ) .
the pseudosarcomatous fibromyxoid tumor of the prostate ( pfmt ) is a rare lesion , which , despite its resemblance to sarcomas , follows a benign course without the need to perform radical retropubic prostatectomy .
another lesion that has a somewhat similar histological appearance to pfmt is the postoperative spindle cell nodule ( poscn ) , which was first described by proppe et al . .
differentiation between poscn and pfmt is based on the few mitoses in the latter and the history of operative trauma in the former .
pfmt is usually characterized by scattered stellate and spindle cells in an edematous , myxoid stroma with large number of capillaries and inflammatory cells .
the nuclei of the stellate and spindle cells are hyperchromatic and pleomorphic ; few , if any mitoses are seen and none are atypical . despite the rarity of pfmt , it is important for urologists and pathologists to recognize and be aware of its benign course in order to avoid unnecessary radical procedures .
 we report a rare case of inflammatory pseudotumor of the prostate revealed on suprapubic prostatectomy . a 70-year - old man presented with nocturia , urgency and difficulty in voiding . 
 the histopathological examination of the suprapubic adenomectomy specimen reported fibromyxoid pseudosarcomatous tumor ( inflammatory prostatic pseudotumor ) . 
 it is important to take this benign lesion under consideration to avoid unnecessary aggressive radical complementary treatments . 