we report a case , carbon dioxide ( co2 ) embolism a potentially devastating complication of laparoscopic surgery , during dissection phase and was successfully resuscitated .
a 35-years - old female , weighing 42 kg was posted for transperitoneal laparoscopic boari 's ureteric reimplantation .
her , physical examination and routine investigations were unremarkable . with routine monitoring , balanced general anesthesia was given .
co2 pneumoperitoneum was created uneventfully using open insufflation technique and sustained with pressure of 14 mm hg .
after 2 h , when the surgeon was dissecting the ureters , there was a sudden drop in etco2 ( 8 mm hg ) , tachycardia ( 130/min ) followed by multiple ventricular premature beats ( vpbs ) with blood pressure ( bp ) 110/72 mm of hg and sao2 - 98% .
surgical bleeding and endotracheal tube blockage were ruled out , and gas embolism was suspected .
injection lignocaine 80 mg intravenously was given for vpbs , and the regular rhythm was restored with the heart rate of 42/min .
at this point , the sao2 decreased from 98% to 77% while the breath sounds were normal with no adventitious sounds .
since there was no response to these measures , injection dopamine 20 ug / kg / min and nor - adrenaline 0.36 ug / kg / min were infused .
multiorifice central venous catheter with its tip at the superior vena cava -right atrium ( svc - ra ) junction was inserted via right internal jugular vein but air could not be aspirated .
after 20 min , resuscitative efforts were successful , patient had pulse rate of 120/min , bp 100/54 mm / hg , sao2 100% , etco2
30 mm / hg and ecg showed sinus rhythm with right ventricular strain pattern.at this time the cvp was found to be 10 mm of hg .
two - dimension echocardiography ( 2-d echo ) showed no patent ductus arteriosus or any other congenital defects .
she was shifted to intensive care unit with dopamine 5 ug / kg / min . which was tapered and stopped after  h. the patient did not receive hyperbaric oxygen as we did not have the facility .
co2 embolism can occur either during peritoneal insufflationor during the surgical dissection . in this case ,
possible causes of sudden cardiovascular collapse like hypovolemia , hemorrhage , vaso - vagal reflex , pneumothorax and endotracheal tube blockage were ruled out before considering gas embolism the adhesions caused by previous surgery might have led to vascular injury during dissection and the operating site was above the level of the heart ( trendelenburg position ) creating a pressure gradient thus the open venous channels , at lower pressure were open to gaseous medium at a higher pressure leading to gas embolism . either , slow infusion of air ( 0.01 - 2.00 ml / kg / min ) or bolus of gas ( 25 - 200 ml or 1 - 13 ml / kg ) , creates a  gas 
paradoxical air embolism was ruled out by a 2-d echo that showed no intra - cardiac channels .
any kind of pulmonary embolism leads to sudden deterioration of the hemodynamic status associated with decreased etco2 levels . since co2 is a highly soluble gas ( 54 ml / dl ) , prompt recovery of the vital signs is usual .
aspiration of gas through central venous catheter is the definitive means of treating gas emboli . in our case ,
failure to aspirate the gas may suggest that it might have been trapped in the pulmonary vasculature .
tee is the gold standard for detection of pulmonary air embolism , however , it is not indicated routinely for intra - operative monitoring .
sudden decrease in etco2 is an early sensitive but nonspecific sign of venous air embolismprecordial stethoscope enhances specificity of etco2 and mean pulmonary artery pressure values .
immediate treatment of gas embolism requires deflation of pneumoperitonium , placing the patient in durant 's position , hyperventilation and administration of 100% oxygen .
aggressive cardiopulmonary resuscitation should be continued till the acute effects of the embolism abate and one should maintain positive circulating volume to prevent further entrainment of the gas .
thus , in laparoscopic surgeries early detection of gas embolism with prompt resuscitation can result in a favorable post - operative outcome .
 carbon dioxide ( co2 ) embolism is a rare but potentially fatal complication of laparoscopic surgery . 
 we report a case of presumed co2 embolism in a 35-year - old female during laparoscopic ureteric reconstructive surgery . 
 after 2 h of operating time , a sudden decrease in end - tidal carbon dioxide and deterioration of hemodynamic status followed by cardiac arrest with pulseless electrical activity suggested gas embolism . 
 immediate cardiopulmonary resuscitation and inotropic support resulted in successful outcome . 
 thus , early recognition of the complication and prompt treatment can avoid catastrophy . 