The minimal inhibitory concentration (MIC) is conventionally used to define in vitro levels of susceptibility or resistance of a specific bacterial strain to an antibiotic and to predict its clinical efficacy. Along with MIC, other measures of bacteria resistance exist: the MIC determined at high bacterial inocula (MICHI) that allow the estimation of the occurrence of inoculum effect (IE) and the mutant prevention concentration, MPC. Together, MIC, MICHIand MPC represent the bacterial “resistance profile”. In this paper, we provide a comprehensive analysis of such profiles ofK. pneumoniaestrains that differ by meropenem susceptibility, ability to produce carbapenemases and specific carbapenemase types. In addition, we have analyzed inter-relations between the MIC, MICHIand MPC for each testedK. pneumoniaestrain. Low IE probability was detected with carbapenemase-non-producingK. pneumoniae,and high IE probability was detected with those that were carbapenemase-producing. MICs did not correlate with the MPCs; significant correlation was observed between the MICHIs and the MPCs, indicating that these bacteria/antibiotic characteristics display similar resistance properties of a given bacterial strain. To determine the possible resistance-related risk due to a givenK. pneumoniaestrain, we propose determining the MICHI. This can more or less predict the MPC value of the particular strain.