BackgroundDuring the initial stages of the coronavirus disease 2019 (COVID-19) pandemic, the administration of antibiotics to patients was prevalent in numerous countries. Despite this, the rising threat of antimicrobial resistance (AMR) presents a significant public health concern. The escalation of AMR has been exacerbated by the ongoing COVID-19 pandemic. Against this backdrop, the primary aim of this study was to conduct a bibliometric and visual analysis of research pertaining to the use of antibiotics in COVID-19.MethodsThis study examined documents indexed in Scopus between 2020 and 2022. To visualize the trends and hotspots of research related to antibiotics and COVID-19, as well as collaborative networks, the researcher utilized version 1.6.18 of the VOSviewer software. Scopus data were analysed to extract information on the types of publications, annual research output, countries, institutions, funding agencies, journals, citations, and highly cited references. Microsoft Excel 2019 was used to process and organize the extracted data.ResultsThis study analysed 1137 documents related to COVID-19 and antibiotics and found that the number of publications increased from 130 in 2020 to 527 in 2022. These publications included 777 (68.34%) articles and 205 (18.03%) reviews. The top five countries in terms of scientific production were the United States (n= 231; 20.32%), the United Kingdom (n= 156; 13.72%), China (n= 101; 8.88%), India (n= 100; 8.8%), and Italy (n= 63; 5.54%), and the leading institutions wereImperial College London(n= 21; 1.85%),University of Oxford(n= 20; 1.76%), andUniversity College London(n= 15; 1.32%). TheNational Natural Science Foundation of Chinaprovided funding for the highest number of articles (n= 48; 4.22%), followed by theNational Institutes of Health(n= 32; 2.81%). The most productive journals wereAntibiotics(n= 90; 7.92%),Journal of Antimicrobial Chemotherapy(n= 30; 2.64%), andInfection Control and Hospital Epidemiology(n= 26; 2.29%). Finally, the research hotspots identified in this study were ‘antimicrobial stewardship during the COVID-19 outbreak’ and ‘implicationsof the COVID-19 pandemic on the emergence of antimicrobial resistance.’ConclusionsThis is the first bibliometric analysis of COVID-19-related research on antibiotics. Research was carried out in response to global requests to increase the fight against AMR and awareness of the issue. More restrictions on the use of antibiotics are urgently needed from policy makers and authorities, more so than in the current situation.