Artificial Intelligence (AI) technologies and data science models may hold potential for enabling an understanding of global health inequities and support decision-making related toward possible interventions. However, AI inputs should not perpetuate the biases and structural issues within our global societies that have created various health inequities. We need AI to be able to ‘see’ the full context of what it is meant to learn. AI trained with biased data produces biased outputs and providing health workforce training with such outputs further contributes to the buildup of biases and structural inequities. The accelerating and intricately evolving technology and digitalization will influence the education and practice of health care workers. Before we invest in utilizing AI in health workforce training globally, it is important to make sure that multiple stakeholders from the global arena are included in the conversation to address the need for training in ‘AIandthe role of AI in training’. This is a daunting task for any one entity and a multi-sectorial interactions and solutions are needed. We believe that partnerships among various national, regional, and global stakeholders involved directly or indirectly with health workforce training ranging to name a few, from public health & clinical science training institutions, computer science, learning design, data science, technology companies, social scientists, law, and AI ethicists, need to be developed in ways that enable the formation of an equitable and sustainable Communities of Practice (CoP) to address the use of AI for global health workforce training. This paper has laid out a framework for such CoP.