BackgroundAs part of a strategy to reduce maternal and perinatal mortality, Ethiopia’s government has made a significant effort to expand the number of Maternity Waiting Homes (MWHs). However, worldwide there is a substantial regional variation in pregnant women’s intention to use MWHs. Therefore, the aim of this study is to assess pregnant women’s intention to use maternity waiting home and its associated factors in the rural district of Hadiya Zone, Southern Ethiopia.MethodsThis was a cross-sectional study carried out on 385 pregnant women from March 1–28, 2020. A systematic random sampling technique was used to recruit the study participants. SPSS software (version 24.0) was used to enter and analyze the data. Bivariate and multivariate logistic regression analyses were used to determine an association between each independent and dependent variables. Odds ratio with their 95% confidence intervals was computed to ascertain the existence and strength of an association, and statistical significance was affirmed at ap-value of < 0.05.ResultsThe prevalence of pregnant women’s intension to use MWHs was observed to be 55.6%. A poor wealth status (AOR = 2.52; 95% CI:1.05–6.05), having a previous history of institutional delivery (AOR = 4.78; 95% CI:1.16–9.64), attending four or more antenatal care visits (AOR = 3.34; 95%CI:1.35–8.29), having obstetric complications during previous pregnancy (AOR = 3.76; 95% CI:1.45–9.77), and having favourable attitude towards MWHs (AOR = 13.51; 95% CI: 5.85–9.54) had a significant association with an intention to use MWHs.ConclusionsAccording to the findings of this study, more than half of pregnant women have been intended to use MWHs. Therefore, boosting the uptake of the antenatal care visit, raising awareness about the risk and consequences of obstetric complications, and strengthening behavioral modification strategies is very crucial to increase pregnant women’s intention to use MWHs.