Intimate partner violence against women (IPVW) is a pressing social issue which poses a challenge in terms of prevention, legal action, and reporting the abuse once it has occurred. However, a significant number of female victims who file a complaint against their abuser and initiate legal proceedings, subsequently, withdraw charges for different reasons. Research in this field has been focusing on identifying the factors underlying women victims’ decision to disengage from the legal process to enable intervention before this occurs. Previous studies have applied statistical models to use input variables and make a prediction of withdrawal. However, none have used machine learning models to predict disengagement from legal proceedings in IPVW cases. This could represent a more accurate way of detecting these events. This study applied machine learning (ML) techniques to predict the decision of IPVW victims to withdraw from prosecution. Three different ML algorithms were optimized and tested with the original dataset to assess the performance of ML models against non-linear input data. Once the best models had been obtained, explainable artificial intelligence (xAI) techniques were applied to search for the most informative input features and reduce the original dataset to the most important variables. Finally, these results were compared to those obtained in the previous work that used statistical techniques, and the set of most informative parameters was combined with the variables of the previous study, showing that ML-based models had a better predictive accuracy in all cases and that by adding one new variable to the previous work’s predictive model, the accuracy to detect withdrawal improved by 7.5%.