Besides natural sunlight and expensive artificial lights, economical indoor white light can play a significant role in activating a catalyst for photocatalytic removal of organic toxins from contaminated water. In the current effort, CeO2has been modified with Ni, Cu, and Fe through doping methodology to study the removal of 2-chlorophenol (2-CP) in the illumination of 70 W indoor LED white light. The absence of additional diffractions due to the dopants and few changes such as reduction in peaks’ height, minor peak shift at 2θ (28.525°) and peaks’ broadening in XRD patterns of modified CeO2verifies the successful doping of CeO2. The solid-state absorption spectra revealed higher absorbance of Cu-doped CeO2whereas a lower absorption response was observed for Ni-doped CeO2. An interesting observation regarding the lowering of indirect bandgap energy of Fe-doped CeO2(∼2.7 eV) and an increase in Ni-doped CeO2(∼3.0 eV) in comparison to pristine CeO2(∼2.9 eV) was noticed. The process ofe-–h+recombination in the synthesized photocatalysts was also investigated through photoluminescence spectroscopy. The photocatalytic studies revealed the greater photocatalytic activity of Fe-doped CeO2with a higher rate (∼3.9 × 10−3min-1) among all other materials. Moreover, kinetic studies also revealed the validation of the Langmuir-Hinshelwood kinetic model (R2= 0.9839) while removing 2-CP in the exposure of indoor light with a Fe-doped CeO2photocatalyst. The XPS analysis revealed the existence of Fe3+, Cu2+and Ni2+core levels in doped CeO2. Using the agar well-diffusion method, the antifungal activity was assessed against the fungusM. fructicolaandF. oxysporum. Compared to CeO2, Ni-doped CeO2, and Cu-doped CeO2nanoparticles, the Fe-doped CeO2nanoparticles have outstanding antifungal properties.