High-story residential structures and off-site prefabrication have been dominant choices in the construction industry. There is a substantial quantity of greenhouse gas (GHG) emissions produced by the construction industry. In fact, the construction industry is responsible for 30 percent of all GHG emissions. In this study, we analyse the differences between the conventional technique of building and the off-site prefabricating construction method. First, we evaluate the emissions emitted from key processes during the off-site prefabricating construction. In addition, we analyse the qualitative and quantitative differences between two prefabrication structural systems, namely concrete and steel, which are the two most common structural systems utilised in residential construction projects in China. We examine and analyse four different case studies in order to exemplify the proposed methodology and offer managerial insights.