Background:we sought to determine the clinical and growth parameters associated
with retinopathy of prematurity (ROP) in infants with necrotizing
enterocolitis (NEC) and spontaneous ileal perforation (SIP).Methods:Retrospective cohort study comparing clinical information before and
following NEC/SIP onset in neonates with and without severe ROP (Type 1 and
2).Results:Those with severe ROP (32/109, 39.5%) had lower GA, BW,
chorioamnionitis, later median onset of ROP diagnosis and received Penrose
drain and had higher AKI, poor weight z scores, poor linear growth, longer
duration of ventilation and higher FIo2 than those without ROP following
NEC/SIP. The GA and diagnosis at later age remained significant for any ROP
on multi regression modelling.Conclusion:The surgical NEC/SIP infants with severe ROP were more likely to be
younger, smaller, had AKI, had higher oxygen exposure and poor weight gain
and linear growth than those without severe ROP.