Surgery performed by a novice neurosurgeon under constant supervision of a senior surgeon with the experience of thousands of operations, able to handle any intraoperative complications and predict them in advance, and never getting tired, is currently an elusive dream, but can become a reality with the development of artificial intelligence methods.This paper has presented a review of the literature on the use of artificial intelligence technologies in the microsurgical operating room. Searching for sources was carried out in the PubMed text database of medical and biological publications. The key words used were “surgical procedures”, “dexterity”, “microsurgery” AND “artificial intelligence” OR “machine learning” OR “neural networks”. Articles in English and Russian were considered with no limitation to publication date. The main directions of research on the use of artificial intelligence technologies in the microsurgical operating room have been highlighted.Despite the fact that in recent years machine learning has been increasingly introduced into the medical field, a small number of studies related to the problem of interest have been published, and their results have not proved to be of practical use yet. However, the social significance of this direction is an important argument for its development.