In the past decade, marine geophysical observations have led to the discovery of thin channels at the base of oceanic plates with anomalous physical properties that indicate the presence of low-degree partial melts. However, mantle melts are buoyant and should migrate toward the surface. We show abundant observations of widespread intraplate magmatism on the Cocos Plate where a thin partial melt channel was imaged at the lithosphere-asthenosphere boundary. We combine existing geophysical, geochemical, and seafloor drilling results with seismic reflection data and radiometric dating of drill cores to constrain the origin, distribution, and timing of this magmatism. Our synthesis indicates that the sublithospheric channel is a regionally extensive (>100,000 km2) and long-lived feature that originated from the Galápagos Plume more than 20 Ma ago, supplying melt for multiple magmatic events and persisting today. Plume-fed melt channels may be widespread and long-lived sources for intraplate magmatism and mantle metasomatism.