AbstractSedum bulbiferumis a traditional medicinal plant in China, with few reports on its chloroplast genome. In this study, the chloroplast genome ofSedum bulbiferumwas characterized, and its phylogenetic position among other closely related species was studied. The results showed that the full length of the chloroplast genome was 150,074 bp, containing a large single-copy (LSC) region and a small single-copy (SSC) region of 81,730 and 16,726 bp, respectively, as well as two inverted repeat regions (IRs) of 25,809 bp like other plants. A total of 128 genes were found, including 83 protein-coding genes, 37 tRNA genes, and eight rRNA genes. Phylogenetic analysis showed thatSedum bulbiferumis closely related toSedum emarginatum, Sedum alfredii, Sedum tricarpum, Sedum plumbizincicola,andSedum sarmentosum.