Atomically precise nanoclusters play an important role in nanoscale catalysis, photonics, and quantum information science. Their nanochemical properties arise from their unique superatomic electronic structures. As the flagship of atomically precise nanochemistry, the Au25(SR)18nanocluster exhibits tunable spectroscopic signatures that are sensitive to the oxidation state. This work aims to unravel the physical underpinnings of the spectral progression of Au25(SR)18nanocluster using variational relativistic time-dependent density functional theory. The investigation will focus on the effects of superatomic spin–orbit coupling, its interplay with Jahn–Teller distortion, and their manifestations in the absorption spectra of Au25(SR)18nanoclusters of different oxidation states.