Topological indices are numerical descriptors that aid in the prediction of chemical molecules' physiochemical properties and biological actions. It is often helpful to forecast numerous physiochemical attributes and biological actions of molecules in chemometrics, bioinformatics, and biomedicine. In this paper, we establish the M-polynomial and NM-polynomial of some very familiar biopolymers, which are xanthan gum, gellan gum, and polyacrylamide. The uses of these biopolymers can increasingly take the place of traditional admixtures for the application of soil stability and enhancement. We recover the important topological degree-based indices. Also, we give diverse graphs of topological indices and their relations with the parameters of structures.