DetectingEscherichia coliis essential in biomedical, environmental, and food safety applications. In this paper, we have developed a simple, rapid, sensitive, and selectiveE. coliDNA sensor based on the novel hybrid-type\documentclass[12pt]{minimal}
				\usepackage{amsmath}
				\usepackage{wasysym} 
				\usepackage{amsfonts} 
				\usepackage{amssymb} 
				\usepackage{amsbsy}
				\usepackage{mathrsfs}
				\usepackage{upgreek}
				\setlength{\oddsidemargin}{-69pt}
				\begin{document}$$\text {MoS}_\text {2}$$\end{document}MoS2and\documentclass[12pt]{minimal}
				\usepackage{amsmath}
				\usepackage{wasysym} 
				\usepackage{amsfonts} 
				\usepackage{amssymb} 
				\usepackage{amsbsy}
				\usepackage{mathrsfs}
				\usepackage{upgreek}
				\setlength{\oddsidemargin}{-69pt}
				\begin{document}$$\mathrm {(NH_4)_6Mo_7O_{24}}$$\end{document}(NH4)6Mo7O24nanosheets. The sensor uses the absorbance measurement to distinguish among the DNA ofE. coli,Vibrio proteolyticus, andBacillus subtiliswhen implemented in conjunction with\documentclass[12pt]{minimal}
				\usepackage{amsmath}
				\usepackage{wasysym} 
				\usepackage{amsfonts} 
				\usepackage{amssymb} 
				\usepackage{amsbsy}
				\usepackage{mathrsfs}
				\usepackage{upgreek}
				\setlength{\oddsidemargin}{-69pt}
				\begin{document}$$\text {NH}_\text {2}$$\end{document}NH2-probes. Our experiments showed that the absorbance increased when sensors detectedE. coliDNA, whereas it decreased when sensors detectedV. proteolyticusandB. subtilisDNA. To the best of authors’ knowledge, there are no reports using the novel hybrid-\documentclass[12pt]{minimal}
				\usepackage{amsmath}
				\usepackage{wasysym} 
				\usepackage{amsfonts} 
				\usepackage{amssymb} 
				\usepackage{amsbsy}
				\usepackage{mathrsfs}
				\usepackage{upgreek}
				\setlength{\oddsidemargin}{-69pt}
				\begin{document}$$\mathrm {MoS_2}$$\end{document}MoS2and\documentclass[12pt]{minimal}
				\usepackage{amsmath}
				\usepackage{wasysym} 
				\usepackage{amsfonts} 
				\usepackage{amssymb} 
				\usepackage{amsbsy}
				\usepackage{mathrsfs}
				\usepackage{upgreek}
				\setlength{\oddsidemargin}{-69pt}
				\begin{document}$$\mathrm {(NH_4)_6Mo_7O_{24}}$$\end{document}(NH4)6Mo7O24materials for differentiating three types of DNA using cost-effective and rapid absorbance measurements. In addition, the label-freeE. coliDNA biosensor exhibited a linear response in the range of 0 fM to 11.65 fM with a limit of detection of 2 fM. The effect of\documentclass[12pt]{minimal}
				\usepackage{amsmath}
				\usepackage{wasysym} 
				\usepackage{amsfonts} 
				\usepackage{amssymb} 
				\usepackage{amsbsy}
				\usepackage{mathrsfs}
				\usepackage{upgreek}
				\setlength{\oddsidemargin}{-69pt}
				\begin{document}$$\text {NH}_\text {2}$$\end{document}NH2-probes on our sensors’ working performance is also investigated. Our results will facilitate further research in pathogen detection applications, which have not been fully developed yet.