BackgroundPeripheral artery disease (PAD) is a vascular disorder leading to serious complications if not managed promptly. This study is conducted to analyze clinical and cardiovascular risk factors in PAD patients presenting at a tertiary care hospital and management strategies.MethodologyThis observational study was conducted at the Department of Cardiology, Mohamed Bin Khalifa Specialist Cardiac Centre. One hundred and twenty patients aged more than 35 years with PAD were included in the study. Data regarding age, gender, physical exam, cardiovascular risk profile, carotid disease, coronary artery disease, and treatment strategy were recorded on a pre-designed questionnaire by the researcher himself. The data were analyzed using IBM Corp. Released 2017. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.ResultsThe mean age of patients with PAD was 65.46±10.56 years. About 79.2% were hypertensive, 81.7% had hyperlipidemia, 83.3% had diabetes, 29.2% had renal insufficiency, and 38.3% were active smokers, respectively. In age ≥65 years, infra-popliteal PAD was significantly lower as compared to above-knee PAD (23.4% vs. 76.6%, p=0.002). In diabetic patients, the proportion of above-knee PAD was higher than below-knee PAD (60% vs. 40%, p=0.033).ConclusionOlder age, diabetes, and carotid disease were significant predictors for peripheral artery disease, and these are significantly associated with above-the-knee peripheral artery disease.