The FEBS‐IUBMB‐ENABLE 1st International Molecular Biosciences PhD and Postdoc Conference was held in Seville, Spain, from the 16–18th of November 2022. Nearly 300 participants from all over the globe were welcomed by the host institution, the Institute of Biomedicine of Seville (IBiS). Following the theme “The perfect tandem: How technology expands the frontiers of biomedicine”, the Scientific Symposium of the conference hosted eight world‐renowned keynote speakers who presented their work in one of the four sessions:Innovation,Basic Research,Translational and Clinical Research, andComputational Biology and Artificial Intelligence. Participants had the chance to present their research to their peers: more than 200 posters were presented during the dedicated poster sessions and 19 selected PhD students and postdocs presented their work as short talks. The Career Day featured a wide range of workshops fully devoted to trainees' professional development, as well as a job fair and career chats with professionals to discuss future perspectives. Besides, several outreach activities were organised before and during the conference to engage with the general public and bring science closer to society. The success of this conference will be followed by the next FEBS‐IUBMB‐ENABLE conferences in Cologne, Germany, in 2023 and Singapore in 2024.