Ribes meyeriis aRibesgenus in the Saxifragaceae family, which is used as both medicine and food. However, the active components and biological activities ofR. meyerifruits are still unknown. In this paper, the phenolic components and their antioxidant and hypoglycemic activities ofR. meyerifruits were studied. Firstly, a total of 42 phenolic components ofR. meyerifruits, including 26 anthocyanins, 9 flavonoids, and 7 phenolic acids, were tentatively identified using HPLC-QTOF-MS/MS, and the main four anthocyanins were quantified using UPLC-MS/MS. The result indicated that cyanidin-3-O-rutinoside is the main anthocyanin in theR. meyerifruits. The anthocyanin fraction ofR. meyerifruits exhibited significant inhibitory activity onα-amylase andα-glucosidase. The anthocyanin fraction fromR. meyerifruits significantly increased the glucose uptake of 3T3-L1 adipocytes. This is the first study of a qualitative and quantitative analysis of the phenolics ofR. meyerifruits.