Secondary incidents are considered a major risk in terms of traffic management due to dangerous ramifications, such as reduced capacity, additional traffic delays, and serious injuries. Therefore, it is necessary to examine what causes a secondary incident to occur after a primary incident and prepare countermeasures to reduce the possible damage to human and property from primary and secondary incidents. In Iowa, a safety service patrol program is being implemented on major highway routes to respond to both types of incident efficiently. However, research on when, where, and under what conditions these incidents occur and how the program can deal with incidents must be conducted to determine the major characteristics of primary and secondary incidents and to estimate the program's performance. Consequently, statistical and spatial analyzes were performed on traffic incidents in a 5-year period (2016–2020) in Iowa. A survival analysis confirmed that the program could decrease the probability of secondary incident occurrences, and 99.9% of secondary incidents occurred within 4 h of the primary incident. Additionally, the binary logistic regression analysis of primary incidents affirmed that a longer incident clearance time and a higher severity of incidents could increase the probability of secondary incidents occurrence. Furthermore, a spatial analysis evaluated that the Iowa DOT safety service patrol program adequately covered areas where primary and secondary incidents are focused. This study is expected to be used to develop countermeasures in both incident cases by identifying the characteristics of secondary and primary incidents in Iowa.