In our research, our goal was to develop a characterization method that can be universally applied to periodic cell structures. Our work involved the accurate tuning of the stiffness properties of cellular structure components that can significantly reduce the number of revision surgeries. Up to date porous, cellular structures provide the best possible osseointegration, while stress shielding and micromovements at the bone-implant interface can be reduced by implants with elastic properties equivalent to bone tissue. Furthermore, it is possible to store a drug inside implants with a cellular structure, for which we have also prepared a viable model. In the literature, there is currently no established uniform stiffness sizing procedure for periodic cellular structures but also no uniform designation to identify the structures. A uniform marking system for cellular structures was proposed. We developed a multi-step exact stiffness design and validation methodology. The method consists of a combination of FE (Finite Element) simulations and mechanical compression tests with fine strain measurement, which are finally used to accurately set the stiffness of components. We succeeded in reducing the stiffness of test specimens designed by us to a level equivalent to that of bone (7–30 GPa), and all of this was also validated with FE simulation.