BackgroundThe gut microbiota plays an important role in human health, as it can affect host immunity and susceptibility to infectious diseases. Invasive intestinal candidiasis is strongly associated with gut microbiota homeostasis. However, the nature of the interaction betweenCandida albicansand gut bacteria remains unclear.ObjectiveThis review aimed to determine the nature of interaction and the effects of gut bacteria onC. albicansso as to comprehend an approach to reducing intestinal invasive infection byC. albicans.MethodsThis review examined 11 common gut bacteria’s interactions withC. albicans, includingEscherichia coli,Pseudomonas aeruginosa,Acinetobacter baumannii,Enterococcus faecalis,Staphylococcus aureus,Salmonella spp.,Helicobacter pylori,Lactobacillus spp.,Bacteroides spp.,Clostridium difficile, andStreptococcus spp.ResultsMost of the studied bacteria demonstrated both synergistic and antagonistic effects withC. albicans, and just a few bacteria such asP. aeruginosa,Salmonella spp., andLactobacillus spp.demonstrated only antagonism againstC. albicans.ConclusionsBased on the nature of interactions reported so far by the literature between gut bacteria andC. albicans, it is expected to provide new ideas for the prevention and treatment of invasive intestinal candidiasis.