The Messinian Qawasim sequence, as one of the most important reservoirs in the Egyptian Nile Delta, represents a typical gas-bearing deltaic reservoir sequence. It aims at delineating the implication of the litho- and microfacies associations on the reservoir characteristics of the different stages of the fluvial deltas including the prodelta, proximal/distal delta front, and the delta plain depositional sequences. The studied reservoir sequence was divided into two units; upper and lower clastic units. The petrophysical properties of these two units were studied on the borehole scale using the gamma-ray, caliper, sonic, density, neutron, and resistivity logs to estimate the reservoir parameters including the total and effective porosities, water saturation, shale volume, and the net-pay thickness. For more details, they are also examined on the plug-scale using the core dataset including helium porosity, density, permeability, and fluids saturations, where the flow zone indicator, the reservoir potentiality index, the reservoir quality index, and the average reservoir pore radius were then estimated. The entire sequence is divided into five reservoir rock types (RRT1-RRT5) where, the best quality is assigned to the first RRT (the upper reservoir unit), and the lowest quality is assigned to the RRT5 of the lower reservoir unit. Based on core description and the petrographical studies five lithofacies and four microfacies have been identified. The lithofacies are (1) laminated mudstones/siltstones, (2) ripple laminated sandstones, (3) cross-laminated sandstones, (4) cross-bedded sandstones, and (5) pebbly massive sandstones. These lithofacies are primarily composed of four microfacies; sublithic arenites, subarkose arenite, glauconitic quartz wacke, and sandy mudstone/siltstone. Based on this study, the pebbly massive and the cross-bedded sandstones of the upper unit which is composed of the sublithic and subarkose arenites (RRT1-RRT2) have the best reservoir quality. On the other hand, the lowest quality is assigned to the RRT5 (sandy mudstone/siltstone microfacies) which is represented on the macro scale by the laminated mudstones/siltstones lithofacies. The integration between multi-scale datasets (core-well, petrography, well logs, and seismic) gives a precise picture of the deltaic Qawasim reservoir rock units in the Nile Delta. This workflow has never been applied to the deltaic system in the onshore Nile delta and North Africa. Thereby, this study is considered a standard case study for the deltaic sequences and its proposed workflow is applicable to the Nile Delta elsewhere and worldwide for similar reservoir sequences.