BackgroundHome confinement during the epidemic has a significant impact on the lifestyle and behavior of school-aged children, who have exhibited an increase in the prevalence and development of myopia. Our research will look at if home confinement will affect school-aged children on myopia control with orthokeratology.MethodData on axial length was gathered from school-aged children who had received OK lenses treatment. The entire data was separated into subgroups based on gender, age, and initial refraction, and the AL changes for each period were calculated using the formula defined in our study. Finally, the acquired data will be examined using various statistical approaches, and the ideas of slow, moderate, and rapid myopia progression will be applied to our study.ResultA total of 258 study subjects met the requirements to be included in the study. We discovered that the percentage of rapid myopia growth increased during the epidemic. In addition, the AL changes before and during the epidemic were found to be statistically significant in 171 subjects in the overall data. (P= 0.041) In the high age group, the AL changes before and during the epidemic、(P= 0.033) before and after the epidemic (P= 0.023) were found to be statistically significant. The AL changes before and during the epidemic (P= 0.035) were shown to be statistically significant in the moderate myopia group. Finally, we did not find statistically significant results for other groups.ConclusionWe cannot conclude that home confinement did have a negative impact on myopia control with orthokeratology in school-aged children. But we found there was an increase in the percentage of patients with OK treatment that had fast myopia progression during the confinement. We also observed that older children with higher initial refraction were more likely to be affected by home confinement.Supplementary InformationThe online version contains supplementary material available at 10.1186/s12886-023-02969-3