Intelligent polymer gel, as a popular polymer material, has been attracting much attention for its application. An intelligent polymer gel will make corresponding changes to adapt to the environment after receiving stimuli; therefore, an intelligent polymer gel can play its role in many fields. With the research on intelligent polymer gels, there is great potential for applications in the fields of drug engineering, molecular devices, and biomedicine in particular. The strength and responsiveness of the gels can be improved under different configurations in different technologies to meet the needs in these fields. There is no discussion on the application of intelligent polymer gels in these fields; therefore, this paper reviews the research progress of intelligent polymer gel, describes the important research of some intelligent polymer gel, summarizes the research progress and current situation of intelligent polymer gel in the environment of external stimulation, and discusses the performance and future development direction of intelligent polymer gel.