To realize the potential of DME for clean combustion, fueling control is essential. In this research, the challenges, advantages, and applicability of high-pressure direct injection and low-pressure port injection are reviewed and evaluated, especially in relevance to HCCI combustion. In this study, emphasis is given to the applicable ranges of low-pressure fuel delivery in relevance to load, air-fuel ratio, and inert gas dilution, for realizing HCCI combustion. The strategy of high-pressure direct injection is advantageous for combustion phasing control, but the fuel handling is challenging because of the high vapor pressure of DME fuel. The strategy of port fuel injection is prone to early combustion and, consequently, tends to produce excessive pressure rise rates in the combustion chamber. This challenge is escalated at higher engine loads, making homogenous charge compression ignition difficult to achieve. In this paper, the load extension of DME-fueled HCCI combustion was explored. First, the impact of dilution on the combustion characteristics of DME HCCI was studied under lean and CO2diluted conditions. Under the present empirical setups, results show that the lean-burn strategy has limited capability of combustion phasing control, especially when the engine load is above 5 bar IMEP. The CO2dilution strategy can significantly retard the combustion phasing until the fulfillment of combustion becomes unstable. It was found that spark assistance is advantageous for combustion control. With an effective application of excess air, intake CO2dilution and spark assistance, an engine load of 8 bar IMEP was reached with appropriate combustion phasing, with ultra-low NOxemissions.