ABSTRACTHere, we report the complete genome sequence ofProteus mirabilisisolate HK294, recovered from pooled poultry feces in Hong Kong in 2022. The chromosome contained 32 antimicrobial resistance genes, including the extended-spectrum β-lactamasesblaCTX-M-65andblaCTX-M-3. Almost all resistance genes were part of either an integrative conjugative element or a Tn7-like transposon.