In this paper, a known mixed-ligand MOF {[Co2(TZMB)2(1,4-bib)0.5(H2O)2]·(H2O)2}n(compound1) was reproduced, and its potential application potential was explored. It was found that compound1had high photocatalytic activity for CO2reduction. After 12 h of illumination, the formation rate of CO, which is the product of CO2reduction by compound1, reached 3012.5 μmol/g/h. At the same time, compound1has a good antibacterial effect onStaphylococcus aureus(S. aureus),Escherichia coli(E. coli) andCandida albicans(C. albicans), which has potential research value in the medical field. In addition, compound1can effectively remove Congo Red from aqueous solutions and achieve the separation of Congo red from mixed dye solutions.