BackgroundTo compare the difference of short-term curative effect between the use of Maryland forceps (MF) and electrocoagulation hooks (EH) in da Vinci robot-assisted thoracoscopic mediastinal tumor resection.MethodsRetrospectively analyze 84 patients with mediastinal tumors who underwent robot-assisted thoracoscopic surgery (RATS) at the Department of Thoracic Surgery in Gansu Provincial Hospital from February 2019 to February 2023. Two groups were divided according to the intraoperative use of energy devices, including 41 cases in the MF group and 43 cases in the EH group. Perioperative clinical data was gathered to compare the short-term efficacy of patients in both groups.ResultsThere were no significant differences in baseline characteristics such as sex (P= 0.685), age (P= 0.165), and tumor size (P= 0.339) between the two groups. Compared with the EH group, patients in the MF group have shorter operative time (P= 0.030), less intraoperative bleeding (P= 0.010), less total postoperative drainage volume (P= 0.001), shorter postoperative drainage time (P= 0.022), shorter hospital stay (P= 0.019), and lower levels of interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-alpha (TNF-α), and cortisol. No statistically significant differences were found between the two groups in terms of total hospitalization costs (P= 0.123), postoperative visual analog scale (VAS) pain scores (P= 0.064), and postoperative complications (P= 0.431).ConclusionUsing MF in RATS for mediastinal tumor is safe and effective, which can reduce the amount of bleeding, reduce the degree of inflammatory reaction, and conducive to the quick recovery of patients.