Key Clinical MessageThe conservative prosthodontic construction of an ocular prosthesis utilizing our novel threaded iris fabrication technique required high time and prosthodontic resource inputs and produced a lifelike aesthetic result.AbstractPatients with ocular defects frequently present with significant local anatomical deficiencies and complex histories and require extensive time and resource inputs to treat. This case report describes the conservative management of an ocular defect completed in a postgraduate prosthodontics clinical residency program utilizing a novel threaded iris fabrication technique.