China has low birth rates at higher parities and intensive grandparental childcare. Despite this, there has been little empirical research into the role of intergenerational support in the transition to second birth. This study examines whether grandparental childcare increases the likelihood and speed of a transition to second birth in the context of relaxations in Chinese family planning policy and whether this differs for working and non-working mothers. Using data from the China Family Panel Studies (2010–2016), the association between grandparental childcare, mother’s working status and second childbirth are explored using split-population survival models to distinguish between the impact on the timing of fertility and ultimate parity progression. The odds of having a second child are four times higher for those who use grandparental childcare than those that don’t. Amongst those who have a second child, grandparental childcare leads to 30% lower odds of transition to second birth than those without grandparental care, each month. Grandparental childcare is also associated with maternal employment, which is itself associated with a sharp decrease in the transition to second birth. At the micro-level, grandparental childcare helps mothers continue working, which in turn defers a second birth. The results emphasise the importance of work-life balance strategies, such as grandparental care, in enabling women of childbearing age to realize their fertility intentions in combination with work.