BackgroundEducation managers are among the most important determinants of a university’s academic pedagogy and plans to improve the quality of education. To improve the quality of education and academic enthusiasm of students in a medical university, it might be necessary to improve the university’s pedagogy paradigm through people who shape this pedagogy. This study aimed to investigate the factors that influence the academic enthusiasm of students in a medical university with the purpose of improving the university’s pedagogy paradigm.MethodsThis cross-sectional descriptive-correlational study was conducted on the students of Alborz University of Medical Sciences in the academic year 2021–2022 (3180 students). The sample size was calculated to be 343 using Cochran’s formula. The participants were recruited by stratified random sampling with respect to the proportion of students in different faculties, disciplines, and education levels. The data collection tool was a researcher-made questionnaire. Data were analyzed by one-sample t-test and confirmatory factor analysis using SMART-PLS and SPSS26.ResultsThe developed model consisted of 3 dimensions (academic, individual and social), 10 components (teaching-learning environment, culture, extracurricular activities, facilities and equipment, attitude, knowledge, skill, classmate, family, relatives and friends) and 64 indicators.ConclusionThe developed model can help medical universities take a step towards improving the academic productivity and performance of their students and gain a competitive advantage in this respect.