The application of deep learning methods in civil engineering has gained significant attention, but its usage in studying chloride penetration in concrete is still in its early stages. This research paper focuses on predicting and analyzing chloride profiles using deep learning methods based on measured data from concrete exposed for 600 days in a coastal environment. The study reveals that Bidirectional Long Short-Term Memory (Bi-LSTM) and Convolutional Neural Network (CNN) models exhibit rapid convergence during the training stage, but fail to achieve satisfactory accuracy when predicting chloride profiles. Additionally, the Gate Recurrent Unit (GRU) model proves to be more efficient than the Long Short-Term Memory (LSTM) model, but its prediction accuracy falls short compared to LSTM for further predictions. However, by optimizing the LSTM model through parameters such as the dropout layer, hidden units, iteration times, and initial learning rate, significant improvements are achieved. The mean absolute error (MAE), determinable coefficient (R2), root mean square error (RMSE), and mean absolute percentage error (MAPE) values are reported as 0.0271, 0.9752, 0.0357, and 5.41%, respectively. Furthermore, the study successfully predicts desirable chloride profiles of concrete specimens at 720 days using the optimized LSTM model.