ABSTRACTIntroduction:Cholecystectomy refers to the surgical removal of the gallbladder. It is indicated in acute cholecystitis, and other complications of gallstones like cholecystitis, pancreatitis and bile duct obstruction, the presence of gallbladder trauma, and gallbladder cancer. The aim of this study was to find out the prevalence of cholecystectomy among patients admitted to the Department of Surgery in a tertiary care centre.Methods:A descriptive cross-sectional study was conducted among patients admitted to the Department of Surgery of a tertiary care centre. Data from 1 July 2021 to 1 July 2022 were collected between 10 February 2023 to 20 February 2023 from the hospital records. Ethical approval was taken from the Institutional Review Committee of the same institute (Reference number: 630/2079/80). Convenience sampling method was used. Documents and medical records of the cholecystectomy patients were assessed for personal data, medical history was extracted and analysed using Microsoft Excel 2016. Point estimate and 95% Confidence Interval were calculated.Results:Among 2452 patients admitted to the Department of Surgery, 894 (36.46%) (34.46-38.26, 95% Confidence Interval) underwent cholecystectomy.Conclusions:The prevalence of cholecystectomy in our study was found to be similar to other studies done in similar settings.