This article addresses unsteady nanofluid flow over a cone with MHD and mixed convection effects. Effects of variable viscosity and viscous dissipation are also considered. The resulting system of equations is tackled through the Homotopy Analysis Method (HAM). The impact of different influential variables on skin friction coefficient, heat and mass flux are discovered through numerical tables and graphs. It is noted that the surface drag force in x and y directions increases against the buoyancy force parameter. Also, it is observed that the tangential and azimuthal velocity decrease against the variable viscosity parameter. Furthermore, the temperature of fluid is observed to decay against the unsteady parameter but it increases against the Eckert number.