Key PointsQuestionHow concordant are currently available tools for aesthetic outcome (AO) assessment after locoregional therapy for breast cancer (BC)?FindingsIn this network meta-analysis of 10 observational studies including 3083 patients with BC who received surgical treatment, expert panel–based and computer-based AO evaluation consistently scored lower than patient-perceived outcomes.MeaningThese findings suggest that standardization, adaptation, and dissemination of available AO tools are needed to improve clinical perceptions of the journey of patients with BC, meet patients’ needs, and refine therapeutic outcome priorities.