Volatile organic compounds (VOCs) are major indoor air pollutants that contain several toxic substances. However, there are few studies on health risk assessments of indoor VOCs in China. This study aimed to determine the concentration characteristics of VOCs on college campuses by collecting VOC samples from different locations on campus during different seasons combined with the exposure times of college students in each location obtained from a questionnaire survey to assess the possible health risks. The highest total VOC concentration (254 ± 101 µg/m3) was in the dormitory. The seasonal variation of TVOC concentrations was related to the variation of emission sources in addition to temperature. Health risk assessments of VOCs were evaluated using non-carcinogenic and carcinogenic risk values, represented by hazard quotient (HQ) and lifetime cancer risk (LCR), respectively. The non-carcinogenic risks at all sampling sites were within the safe range (HQ< 1). Dormitories had the highest carcinogenic risk, whereas the carcinogenic risk in the other three places was low (withLCR< 1.0 × 10−6). Moreover, 1,2-dichloroethane was identified as a possible carcinogenic risk substance in the dormitory due to its highLCR(1.95 × 10−6). This study provides basic data on health risks in different locations on campus and a basis for formulating measures to improve people’s living environments.