Research into biomimetics has focused on science and technology, often developing the innovative parts of buildings from nature, leading to a new field of bioinspired architecture. The work of Frank Lloyd Wright is presented as an early example of bioinspired architecture and explores how buildings might be more broadly integrated into their site and environment. Integrating architecture, biomimetics and eco-mimesis as a framework to look at the work of Frank Lloyd Wright, provides a new understanding of his architecture and directions for future research into the ecological design of buildings and cities.