Base-mediated rearrangement
of 1,3-dithianyl-substituted
propargylamines
in DMF via expansion of the dithiane ring has been reported. The rearrangement
provided 9-membered amino-functionalized sulfur-containing heterocycles
(dithionine derivatives) in good yields under mild conditions. Propargylamines
bearing 5-membered 1,3-dithiolane and 7-membered 1,3-dithiepane rings
rearranged in a similar manner yielding 8- and 10-memberedS,S-heterocycles, respectively.