This study aimed to give a new theoretical recommendation for non-dimensional parameters depending on the fluid temperature and concentration. This suggestion came from the fact of fluid density may change with the fluid temperature (\documentclass[12pt]{minimal}
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				\begin{document}$$\theta $$\end{document}θ) and concentration (\documentclass[12pt]{minimal}
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				\begin{document}$$\varphi $$\end{document}φ). So, a newly released mathematical form of Jeffrey fluid with peristalsis through the inclined channel is constructed. The problem model defines a mathematical fluid model which converts using non-dimensional values. A sequentially used technique called the Adaptive shooting method for finding the problem solutions. Axial velocity behavior has become a novel concern to Reynolds number. In contradiction to different values of parameters, the temperature and concentration profiles are designated/sketched. The results show that the high value of the Reynolds number acts as a fluid temperature damper, while it boosts the concentration of the fluid particle. The non-constant fluid density recommendation makes the Darcy number controls with a fluid velocity which is virtually significant in drug carries applications or blood circulation systems. To verify the obtained results, a numerical comparison for obtained results has been made with a trustful algorithm with aid of AST using wolfram Mathematica version 13.1.1.