Orthognathic surgeries are considered successful on the basis of postoperative stability, vascularity, and relapse rates. One among them is the multisegment Le Fort I osteotomy, which has often been disregarded due to vascular compromise. The complications associated with such an osteotomy are also primarily due to vascular ischemia. In the past, it was hypothesized that segmentation of the maxilla disrupted vascular supply to the osteotomized segments. However, the case series attempts to analyze the complications associated with a multisegment Le Fort I osteotomy and its incidence. This article documents four such cases that involve a Le Fort I osteotomy along with anterior segmentation. The patients experienced minimal or no postoperative complications. Thus, the case series exhibits that multisegment Le Fort I osteotomies can be successfully carried out without much complications and hence prove to be a safe treatment option in cases of increased advancement, setback, or combination.