Accurate prediction of springback is increasingly required during deep-drawing formation of anisotropic stainless steel sheets. The anisotropy of sheet thickness direction is very important for predicting the springback and final shape of a workpiece. The effect of Lankford coefficients (r00, r45, r90) with different angles on springback was investigated using numerical simulation and experiments. The results show that the Lankford coefficients with different angles each have a different influence on springback. The diameter of the straight wall of the cylinder along the 45-degree direction decreased after springback, and showed a concave valley shape. The Lankford coefficient r90had the greatest effect on the bottom ground springback, followed by r45and then r00. A correlation was established between the springback of workpiece and Lankford coefficients. The experimental springback values were obtained by using a coordinate-measuring machine and showed good agreement with the numerical simulation results.