The irrational use of synthetic pesticides in agriculture has had negative impacts on ecosystems and contributed to environmental pollution. Botanical pesticides offer a clean biotechnological alternative to meet the agricultural challenges posed by pests and arthropods. This article proposes the use of fruit structures (fruit, peel, seed, and sarcotesta) of severalMagnoliaspecies as biopesticides. The potential of extracts, essential oils, and secondary metabolites of these structures for pest control is described. From 11Magnoliaspecies, 277 natural compounds were obtained, 68.7% of which were terpenoids, phenolic compounds, and alkaloids. Finally, the importance of a correct management ofMagnoliaspecies to ensure their sustainable use and conservation is stressed.