Terror Management Theory (TMT) postulates that humans, in response to awareness of their death, developed complex defenses to remove the salience and discomfort stemming from those thoughts. In a standard paradigm to test this theory, an individual is presented with a death-related prime (Mortality Salience; MS), such as writing the details of their own death, or something neutral, such as watching television. After a distractor task (for delay), participants complete the dependent variable, such as rating how much they like or agree with a pro- or anti-national essay and its author. Individuals in the MS condition typically exhibit greater worldview defense than control conditions by rating the pro-national essay more positively and the anti-national essay more negatively. We completed five separate studies across five unique samples with the goal of replicating and extending this well-established pattern to provide further understanding of the phenomena that underlie the effects of MS. However, despite using standard procedures, we were unable to replicate basic patterns of the dependent variable in the MS conditions. We also pooled all responses into two meta-analyses, one examining all dependent variables and one focusing on the anti-national essay; yet the effect sizes in these analyses did not significantly differ from zero. We discuss the methodological and theoretical implications of these (unintended) failures to replicate. It is not clear if these null findings were due to methodological limitations, restraints of online/crowd-sourced recruitment, or ever-evolving sociocultural factors.