SignificanceWe have identified and characterized a previously unknown gene controlling plant height in wheat and named itPLATZ1. Mutations inPLATZ1reduce plant height while its overexpression results in taller plants.PLATZ1is expressed mainly in elongating stems and developing spikes and shows a significant genetic interaction on plant height with the “Green Revolution” dwarfing geneREDUCED HEIGHT 1(RHT1). We identified five natural mutations in the A genome copy ofPLATZ1in common wheat that have been favored during breeding, suggesting an overall positive effect on wheat performance. These mutations can be used to fine-tune wheat plant height and, eventually, to replace theRHT1dwarfing alleles that impose limitations on planting depth and grain yield potential in some environments.