The present study reports an asymmetric organocascade
reaction
of oxindole-derived alkenes with 3-bromo-1-nitropropane efficiently
catalyzed by the bifunctional catalyst. Spirooxindole-fused cyclopentanes
were produced in moderate-to-good isolated yields (15–69%)
with excellent stereochemical outcomes. The synthetic utility of the
protocol was exemplified on a set of additional transformations of
the corresponding spirooxindole compounds.