BackgroundThe surgical procedure for laparoscopic right colectomy (LRC) is not standardized. Some published studies show the superiority of ileocolic anastomosis (IIA), but the evidence so far is insufficient. This study aimed to investigate the potential advantages in postoperative recovery and safety of IIA in LRC.MethodsA total of 114 patients who underwent LRC with IIA (n= 58) or extracorporeal ileocolic anastomosis (EIA,n= 56) between January 2019 and September 2021 were enrolled. We collected certain factors as clinical features, intraoperative characteristics, oncological outcomes, postoperative recovery, and short-term outcomes. Our primary outcome was time to gastrointestinal (GI) function recovery. Secondary outcomes were postoperative complications within 30 days, postoperative pain, and length of hospital stay.ResultsFaster GI recovery and less postoperative pain were observed in patients with IIA compared to EIA [time to first flatus: (2.4 ± 0.7) vs (2.8 ± 1.0) days,p< 0.01; time to liquid intake: (3.5 ± 0.7) vs (4.0 ± 1.1) days,p= 0.01; postoperative visual analogue scale score: (3.9 ± 1.0) vs (4.3 ± 0.6),p= 0.02]. No significant differences were detected in oncological outcomes or postoperative complications. IIA, rather than EIA, tended to be performed in patients with higher body mass index [(23.93 ± 3.52) vs (22.36 ± 2.87) kg/m2,p= 0.01].ConclusionsIIA is associated with faster GI function recovery and less postoperative pain and may be more favorable for obese patients.