AbstractObjectivesSchistosomiasis is a blood fluke parasitic illness affecting human lives in rural endemic areas. This study evaluated the performance ofSchistosomaICT IgG-IgMfor screening urinary schistosomiasis in Nigeria.MethodsThree hundred and seventy four (374) urine samples were examined. Reagent strips, urine filtration andSchistosomaICT IgG-IgMwere used for analysis.SchistosomaICT IgG-IgMused 2 mL of each serum for serological examination. Then, 3 mL of each preserved serum was sent to LDBIO Diagnostics, France for re-examination withSchistosomaICT IgG-IgM and confirmation with SCHISTO Western blot (WB) IgG. The performance of the index tests was determined using sensitivity (Se), specificity (Sp), positive predictive value (PPV), negative predictive value (NPV) and positive likelihood ratio (PLR). The Youden index (YI) and diagnostic accuracy (DA) were used to determine the accuracy of each test. The statistical significance was at p-value ≤0.05.ResultsThe test had a sensitivity of 94.9%, specificity of 63.9%, positive predictive value of 72.4%, negative predictive value of 92.6%, and positive likelihood ratio of 2.62.Schistosoma ICT IgG-IgMhad a good Cohen’s kappa index (κ=0.68), good Youden index (YI=0.58) and good diagnostic accuracy (DA=0.78).ConclusionsSchistosomaICT IgG-IgMhas proven to be the best technique for the screening of urinary schistosomiasis in Nigeria.