ObjectiveThe use of donor oocytes in assisted reproduction has seen a significant rise worldwide
in the last two decades. Postponement of motherhood and premature ovarian insufficiency
are the main reasons for the increase in the number of in vitro fertilization cycles
with donor oocytes. The present study aims to characterize donor oocyte cycles to
analyze factors that may have an effect on live births and clinical pregnancy
outcomes.MethodsData were obtained from a single Assisted Reproduction Center in southern Brazil.
Recipient demographics (n=148 patients) and cycle characteristics (n=213 cycles; 50
patients did more than one IVF attempt) were analyzed. Statistical analysis was
performed using chi-squared and t-test as appropriate.ResultsOn average, recipients that reached gestation were significantly younger than the ones
that did not. We also observed a significant positive effect of constant dose estrogen
therapy on pregnancies.ConclusionsPatient age and response to estradiol therapy are important factors in the attainment
of the best possible outcomes in cycles with donor oocytes.