Soft materials that can demonstrate on demand reconfigurability and changing compliance are highly sought after as actuator materials in many fields such as soft robotics and biotechnology. Whilst there are numerous proof of concept materials and devices, rigorous predictive models of deformation have not been well-established or widely adopted. In this paper, we discuss programming complex three-dimensional deformations of a soft intrinsically anisotropic material by controlling the orientation of the contractile units and/or direction of the applied electric field. Programming is achieved by patterning contractile units and/or selectively activating spatial regions. A new constitutive model is derived to describe the soft intrinsic anisotropy of soft materials. The model is developed within a continuum mechanics framework using an invariant-based formulation. Computational implementation allows us to simulate the complex three-dimensional shape response when activated by electric field. Several examples of the achievable Gauss-curved surfaces are demonstrated. Our computational analysis introduces a mechanics-based framework for design when considering soft morphing materials with intrinsic anisotropy, and is meant to inspire the development of new soft active materials.