IntroductionMortality is generally higher among patients with coronavirus disease 2019 (COVID-19) than non-COVID-19 patients, especially critically ill patients. The Acute Physiology and Chronic Health Evaluation IV (APACHE IV) predicts mortality rate (MR); however, it was not designed for COVID-19 patients. Multiple indicators have been utilized in healthcare to measure the performance of intensive care unit (ICU) departments, including length of stay (LOS) and MR. The 4C mortality score was recently developed using the ISARIC WHO clinical characterization protocol. This study aims to evaluate intensive care unit performance using LOS, MR, and 4C mortality scores at East Arafat Hospital (EAH), Makkah region, which is considered the largest COVID-19-designated intensive care unit in the Western region of Saudi Arabia.Materials and methodsA retrospective observational cohort study was conducted on data from patients’ records during the COVID-19 pandemic, from March 1, 2020, to October 31, 2021, at EAH, Makkah Health Affairs. Data to calculate LOS, MR, and 4C mortality scores were collected from the eligible patients' files by a trained team. Demographic (age and gender) and clinical data on admission were collected for statistical purposes.ResultsA total of 1298 patient records were included in the study; 417 (32%) of the patients were female and 872 (68%) were male. The cohort included 399 deaths (total MR=30.7%). Most deaths occurred in the 50-69-year age group, with significantly more deaths among female patients than male patients (p=0.004). A significant association was found between the 4C mortality score and death (p<0.000). Furthermore, the mortality odds ratio (OR) was significant (OR=1.3, 95% CI=1.178-1.447) for each added 4C score.ConclusionOur study metrics regarding LOS were generally higher than most internationally reported values and slightly lower than locally reported values. Our reported MR was comparable with overall published MRs. The ISARIC 4C mortality score was highly compatible with our reported MR between scores 4 and 14; however, the MR was higher for scores 0-3 and lower for scores ≤15. The overall performance of the ICU department was considered generally good. Our findings are helpful for benchmarking and motivating better outcomes.