Highlights•Immediate drop in occupational naloxone trainees after COVID-19 stay-at-home order.•No change in lay naloxone trainees immediately after COVID-19 stay-at-home order.•Naloxone trainings recovered over the 12-month period after stay-at-home order.•Strengthening connections between responder types can help maintain naloxone access.•Programs should consider alternate naloxone delivery models for future emergencies.