BackgroundInfection prevention and control (IPC) is an evidence-based and practical approach to prevention of harm by infection (Infection prevention and controlhttps://www.who.int/health-topics/infection-prevention-and-control#tab=tab_1). IPC recommendations targeted at community-acquired infection aim to prevent illness and subsequent hospital readmission. Cohesive guidance for parents of preterm infants has not been clearly established. The review objectives are to identify and map the global characteristics of IPC measures/recommendations for parents of preterm infants discharged home to the community.MethodsThe scoping review will be conducted using the JBI methodological approach for scoping reviews and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Scoping Review extension (PRISMA ScR) and the PRISMA extension for reporting literature searches in systematic reviews. Electronic databases will be searched and limited by publication year (2013-present day). Grey literature, reference lists and expert-provided sources will be searched against predetermined criteria. A minimum of two authors will independently screen evidence sources and chart evidence on a predetermined charting form. Sources including IPC measures, or recommendations for parents of preterm infants during discharge planning or in the community/home, will be permitted within inclusion criteria. Limits include human studies only and evidence from 2013-present day. Recommendations aimed at professional implementation will be excluded. A descriptive summary of findings will be presented, with diagrammatic and tabular representation.DiscussionCollated evidence will guide future research which will subsequently aim to develop policy and enhance clinical approaches.Systematic review registrationThis review has been registered on the Open Science Framework (OSF) 4th May 2021, available athttps://osf.io/9yhzk.Supplementary InformationThe online version contains supplementary material available at 10.1186/s13643-023-02236-y.