BackgroundFunctional social support (FSS) has been shown to be positively associated with better cognitive function, especially memory, in cross-sectional and longitudinal studies. To better understand this complex association, researchers should consider the impact of additional factors that affect both FSS and memory. Therefore, we conducted a systematic review to examine whether one such factor, marital status or related variables (e.g., FSS from spouses compared to FSS from relatives or friends), affects (e.g., confounds or modifies) the association between FSS and memory in middle-aged and older adults.MethodsWe searched PubMed, PsycINFO, and Scopus from database inception to June 2022. Eligible articles examined the association between FSS and memory, and included marital status or related variables in the analysis. Data were synthesized narratively and reported in accordance with the Synthesis without meta-analysis (SWiM) guidelines; risk of bias was assessed using the Newcastle-Ottawa Scale (NOS).ResultsFour articles were included in the narrative synthesis. All four articles had a low risk of bias. Overall findings suggested some positive associations between FSS from a spouse/partner and memory; however, effect sizes were small and similar to other sources of support, including children, relatives, and friends.ConclusionsOur review is the first attempt to synthesize the literature on this topic. Despite theoretical support for examining the impact of marital status or related variables on the association between FSS and memory, published studies explored this issue secondarily to other research questions.Supplementary InformationThe online version contains supplementary material available at 10.1186/s12877-023-03982-3.