Two new bacterial strains, Marseille-P2698T(CSUR P2698 = DSM 103,121) and Marseille-P2260T(CSUR P2260 = DSM 101,844 = SN18), were isolated from human stools by the culturomic method. We used the taxonogenomic approach to fully describe these two new bacterial strains. The Marseille-P2698Tstrain was a Gram-negative, motile, non-spore-forming, rod-shaped bacterium. The Marseille-P2260Tstrain was a Gram-positive, motile, spore-forming rod-shaped bacterium. Major fatty acids found in Marseille-P2698Twere C15:0 iso(63%), C15:0 anteiso(11%), and C17:0 3-OH iso(8%). Those found in Marseille-P2260Tstrain were C16:00(39%), C18:1n9(16%) and C18:1n7(14%). Strains Marseille-P2698Tand Marseille-P2260Thad 16S rRNA gene sequence similarities of 91.50% withOdoribacter laneusT, and of 90.98% and 95.07% withOdoribacter splanchnicusTandEubacterium sulciT, respectively. The exhibited digital DNA-DNA Hybridization values lower than 20.7%, and Orthologous Average Nucleotide Identity values lower than 73% compared to their closest related bacterial speciesO. splanchnicusTandE. sulciTrespectively. Phenotypic, biochemical, phylogenetic, and genomic results obtained by comparative analyses provided sufficient evidence that both of the two studied strains Marseille-P2698Tand Marseille-P2260Tare two new bacterial species and new bacterial genera for which the namesCulturomica massiliensisgen. nov., sp. nov., andEmergencia timonensisgen. nov., sp. nov. were proposed, respectively.