This study investigates the influence of longitudinal through voids on vault lining. Firstly, a loading test was carried out on a local void model, and the CDP model was used for numerical verification. It was found that the damage to the lining caused by a longitudinal through void was primarily located at the void boundary. On the basis of these findings, an overall model of the vault’s through void was established using the CDP model. The effects of the void on the circumferential stress, vertical deformation, axial force, and bending moment of the lining surface were analyzed, and the damage characteristics of the vault’s through void lining were studied. The results indicated that the through void of the vault caused circumferential tensile stress on the lining surface of the void boundary, while the compressive stress of the vault increased significantly, resulting in a relatively uplifted vault. Furthermore, the axial force within the void range decreased, and the local positive bending moment at the void boundary increased significantly. The impact of the void increased gradually with the height of the void. If the height of the longitudinal through void is large, the inner surface of the lining at the void boundary will crack longitudinally, and the vault will be at risk of falling blocks or even being crushed.