<s>[INST] context: ANS. CVegetations in various conditionsAnother important question in cardiology is gross and microscopic changes in myocardial infarction (May AIIMS 2016)Morphologic changes of myocardial infarctionTime after onsetGross examinationLight microscopy4-12No obvious changeCoagulation necrosis; edema; hemorrhage<24Dark mottlingCoagulation necrosis (eosinophilia)Pyknosis of nuclei and vacuolar degeneration "Wavy fibers"1-3 daysMottling with yellow- tan infarct centerCoagulation necrosisLoss of nuclei and striationsNeutrophilic infiltration3-7 daysCentral yellow- tan softening with hyperemic borderMyofibers desolutionNeutrophilic decreasePhagocytosis of dead cells by macrophages at infarct border7-10 daysDepressed red-tan marginsGranulation tissue formation10-14 daysNoticible infarct bordersWell-established granulation tissue with collagen deposition2-8 weeksInward progression of scarIncreased collagen deposition with decreased cellularity>2 monthsScarring completeDense collagenous scarMicroscopic features of myocardial infarction [/INST] question: A 30-year-old male patient presented with dyspnea ECHO showed mitral stenosis with left atrial hypertrophy. Excised mitral valve is as shown. What is the diagnosis? | options: A: Tuberculosis B: Sarcoidosis C: Rheumatic heart diseases D: Fungal granuloma | answer: C </s>