<s>[INST] context: Varicella virus Congenital Varicella syndrome is characteristically associated with limb reduction defects (if infection occurs prior to limb bud formation) and scarring of skin The association of Limb reduction defects with scarring of skin suggests the diagnosis of congenital varicella syndrome. Limb reduction defects (Limb hypoplasia) and congenital varicella. Limb reduction defects are seen if infection occurs prior to or during limb bud formation. The virus has a tendency to select tissues that are in a rapid development stage such as the limb buds Fetus infected at 6-12 weeks of gestation appears to have maximal interruption with limb development. This may result in 1 or more shoened and malformed extremities. The remaining of the torso may be entirely normal in appearance. Scarring of Skin (Cicatrical skin lesions) and Varicella Scarring of skin is a common feature of congenital varicella syndrome. The characteristic cutaneous lesion has been called a 'Cicatrix' 'Cicatrix' represents zigzag scarring in a dermatomal distribution (and is often associated with atrophy of the affected limb) This characteristic cicatrical scaring is believed to represent the cutaneous residua of WV infection of the sensory nerves analogous to herpes zoster. [/INST] question: Hypoplasia of limbs & scarring is caused due to aEUR' | options: A: Varicella B: Herpes simplex C: Rubella D: Toxoplasma | answer: A </s>