I try to make it less overwhelming by tackling one room at a time. For each room I make piles of:

Maybe Keep

Anything in the keep pile I go through again and try and put in a Toss, Sell or Donate. If it made the maybe keep pile in the first place it probably wasn't that important anyway.

I have quite a garage sale pile already and wish it were Spring so I could have the sale. Will keep you posted on when it will be. Lots of:

Holiday Decorations
Small Kitchen Appliances
Bathroom and Kitchen Supplies
Craft Supplies
Books and Games
Mens Womens and Kids Clothing
Doors, Misc Building Supplies and Underlay
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