After one week of taking the drug, the symptoms are not relieved, or the symptoms are aggravated, or new serious symptoms appear.
4. daysbọchị atọ ka ị rụsịrị ọgwụ ahụ, mgbaàmà ya adịghị emeziwanye, ma ọ bụ agbọ agbọ na afọ ọsịsa pụtara ìhè, ihe mgbaàmà ndị ọzọ siri ike kwesịrị ịga ụlọ ọgwụ.