 ዋና ዋና ገጸ - የሎስ ሳንቶስ ከተማ ጀምሮ እስከ ሦስት ወንጀለኞች: ፍራንክሊን, ማይክል እና ትሬቨር.
The game is set in the fictional city of Los Santos [based off of Los Angeles], and its plot follows three criminals: Franklin Clinton, Michael De Santa, and Trevor Philips.