 ዓይነት II 5a-reductase isozyme በዋነኝነት በፕሮስቴት, በሴሚኒየል ፔሴል, በፒድዲሚዲየስ, እና በፀጉር እና በሆድ ነቀርሳዎች ውስጥ የሚገኝ ሲሆን ለ 2/3 ኛ የ DHT መዘዋወር ሃላፊነት አለበት.
The Type II 5a-reductase isozyme is primarily found in prostate, seminal vesicles, epididymides, and hair follicles as well as liver, and is responsible for two-thirds of circulating DHT.