1950 ኢርቪን ሻርጋፍ የተባሉ የባዮኬሚስትሪ ባለሙያ የዲ ኤን ኤ አወቃቀር ከአንዱ ፍጡር ወደ ሌላው እንደሚለያይ ተገነዘቡ።
In 1950, Austrian biochemist Erwin Chargaff then demonstrated that bases in DNA occur in pairs and that the base composition of DNA varies between species.