In addition, tamoxifen up-regulates the production of transforming growth factor β (TGFβ), a factor that inhibits tumor cell growth, and down-regulates insulin-like growth factor 1 (IGF-1), a factor that stimulates breast cancer cell growth.
Intaa ka sokow, tamoxifen waxay kor u qaadeysaa wax soo saarka kobcinta isbeddelka B (TGFb), taas oo keeneysa kororka unugyada unugyada kansarka, hoosna u xakameynaya saameynta kiniinka insulin-sida 1 (IGF-1), taas oo keenaysa kobaca kansarka naasaha .