Because "Riboxin" and its metabolites are excreted mainly by the kidneys, it is not recommended that the drug be administered in the presence of renal failure.
Njengoba "Riboxinum" futhi metabolites zalo excreted ngokuyinhloko izinso, ke asifanele ukusetshenziswa kwezidakamizwa ebukhoneni ukwehluleka kwezinso.