A range of radicals are produced by KatG activation of isoniazid, including nitric oxide,[8] which has also been shown to be important in the action of another antimycobacterial prodrug PA-824.[9]
Ububanzi ezizivelelayo akhiqizwa KatG ukusebenza isoniazid, kuhlanganise i-nitrous nitric, nakho okuye kwabonakala ukuthi ibalulekile isenzo lomunye prodrug antimycobacterial PA-824 [2, 3].