For more advanced disease, Stages III and IV, the basic approach to initial treatment is the same: surgery to reduce the amount of tumor, radiation, and chemotherapy.
Ukuze izigaba kamuva zezifo, isigaba III futhi IV, indlela eyisisekelo preprocessing okufanayo: ukuhlinzwa ukuze isimila ivolumu, welashwa ngemisebe nangamakhemikhali ukunciphisa.