Resistance among the parasites has developed to several antimalarial medications; for example, chloroquine-resistant P. falciparum has spread to most malarial areas, and resistance to artemisinin has become a problem in some parts of Southeast Asia.
Switsongwatsongwana swin'wana swi sungule ku tolovela mirhi yotala, hixikombiso chloroquine yitsandzeka ku dlaya xivungu xa P. falciparum lexi vangaku dzedzedze etindzhawini to tala, artemisinin yikumana na thlonthlo wo hetisa switsongwatsongwana etindzhawini tin'wana ta ledzongeni bya vuxa wa Axiya.[4]