Exon skipping is an example of what type of splicing?
comprehensive
inclusive
proactive
alternative
One example of alternative splicing is with exon skipping. The D. melanogaster (fruit fly) doublesex (dsx) gene is involved in the fly's determination system. Pre-mRNAs from this gene contain 6 eons, numbered 1-6. In males, exons 1,2,3,5,and 6 are spliced together to form the mRNA, which encodes a transcriptional regulatory protein required for male development. In females, exons 1, 2, 3, and 4 are joined, and a polyadenylation signal in exon 4 causes cleavage of the mRNA at that point. The resulting mRNA is a transcriptional regulatory protein required for female development.