Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients. Effects of Cinnamon Consumption on Glycemic Status, Lipid Profile and Body Composition in Type 2 Diabetic Patients Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Insulin resistance improvement by cinnamon powder in polycystic ovary syndrome: A randomized double‐blind placebo controlled clinical trial Effects of Cinnamon, Cardamom, Saffron, and Ginger Consumption on Markers of Glycemic Control, Lipid Profile, Oxidative Stress, and Inflammation in Type 2 Diabetes Patients. Cinnamon improves glucose and lipids of people with type 2 diabetes.
In vitro and in vivo animal studies have reported strong insulin-like or insulin-potentiating effects after cinnamon administration . Recently , a human intervention study showed that cinnamon supplementation ( 1 g/d ) strongly reduced fasting blood glucose concentration ( 30 % ) and improved the blood lipid profile in patients with type 2 diabetes . The objective of this study was to investigate the effects of cinnamon supplementation on insulin sensitivity and /or glucose tolerance and blood lipid profile in patients with type 2 diabetes . Therefore , a total of 25 postmenopausal patients with type 2 diabetes ( aged 62.9 + /- 1.5 y , BMI 30.4 + /- 0.9 kg/m2 ) participated in a 6-wk intervention during which they were supplemented with either cinnamon ( Cinnamomum cassia , 1.5 g/d ) or a placebo . Before and after 2 and 6 wk of supplementation , arterialized blood sample s were obtained and oral glucose tolerance tests were performed . Blood lipid profiles and multiple indices of whole-body insulin sensitivity were determined . There were no time x treatment interactions for whole-body insulin sensitivity or oral glucose tolerance . The blood lipid profile of fasting subjects did not change after cinnamon supplementation . We conclude that cinnamon supplementation ( 1.5 g/d ) does not improve whole-body insulin sensitivity or oral glucose tolerance and does not modulate blood lipid profile in postmenopausal patients with type 2 diabetes . More research on the proposed health benefits of cinnamon supplementation is warranted before health cl aims should be made Objective : Type 2 diabetes is the most common metabolic disorder worldwide . Traditional herbs and spices can be used to control blood glucose concentrations . The objective of this study was to evaluate the effects of the daily intake of three grams cinnamon over eight weeks on glycemic status , lipid profiles and body composition in type 2 diabetic patients . Methods : A double blind , r and omized , placebo controlled clinical trial was conducted on 44 patients with type 2 diabetes . Participants were r and omly assigned to take either a three g/day cinnamon supplement ( n=22 ) or a placebo ( n=22 ) for eight weeks . Weight , height , body fat mass and systolic and diastolic blood pressure were measured at baseline and after intervention . The fasting blood glucose , insulin , HbA1c , total cholesterol , LDL C , HDL C , Apo lipoprotein A I and B were measured at baseline and endpoint . Results : From 44 subjects participated in this study 37 completed the study . There were no significant differences in baseline characteristics , dietary intake and physical activity between groups . In the treatment group , the levels of fasting blood glucose , HbA1c , triglyceride , weight , BMI and body fat mass decreased significantly compared to baseline , but not in placebo group . No significant differences were observed in glycemic status indicators , lipid profile and anthropometric indicators between the groups at the end of intervention . Conclusion : These data suggest that cinnamon may have a moderate effect in improving glycemic status indicators AIMS To determine the blood glucose lowering effect of cinnamon on HbA1c , blood pressure and lipid profiles in people with type 2 diabetes . METHODS 58 type 2 diabetic patients ( 25 males and 33 females ) , aged 54.9 ± 9.8 , treated only with hypoglycemic agents and with an HbA1c more than 7 % were r and omly assigned to receive either 2 g of cinnamon or placebo daily for 12 weeks . RESULTS After intervention , the mean HbA1c was significantly decreased ( P<0.005 ) in the cinnamon group ( 8.22 % to 7.86 % ) compared with placebo group ( 8.55 % to 8.68 % ) . Mean systolic and diastolic blood pressures ( SBP and DBP ) were also significantly reduced ( P<0.001 ) after 12 weeks in the cinnamon group ( SBP : 132.6 to 129.2 mmHg and DBP : 85.2 to 80.2 mmHg ) compared with the placebo group ( SBP : 134.5 to 134.9 mmHg and DBP : 86.8 to 86.1 mmHg ) . A significant reduction in fasting plasma glucose ( FPG ) , waist circumference and body mass index ( BMI ) was observed at week 12 compared to baseline in the cinnamon group , however , the changes were not significant when compared to placebo group . There were no significant differences in serum lipid profiles of total cholesterol , triglycerides , HDL and LDL cholesterols neither between nor within the groups . CONCLUSIONS Intake of 2 g of cinnamon for 12 weeks significantly reduces the HbA1c , SBP and DBP among poorly controlled type 2 diabetes patients  . Cinnamon supplementation could be considered as an additional dietary supplement option to regulate blood glucose and blood pressure levels along with conventional medications to treat type 2 diabetes mellitus Our aim is to assess the effect of cinnamon powder capsules on insulin resistance , anthropometric measurements , glucose and lipid profiles , and and rogens of women with polycystic ovarian syndrome ( PCOS ) . Out of 80 women that were diagnosed as PCOS by Rotterdam Criteria , 66 were enrolled in this r and omized double-blind placebo-controlled clinical trial . All of the PCOS women were taking medroxy progesterone acetate 10 mg/day for the last 10 days of their menstrual cycles . The cases were r and omly allocated to 2 groups . The women in the first group were treated by cinnamon powder capsules 1.5 g/day in 3 divided doses for 12 weeks and the second group by similar placebo capsules .  Anthropometric measurements , fasting blood sugar , fasting insulin , blood glucose 2 hr after taking 75 g oral glucose , HbA1c , testosterone , dehydroepi and rosterone sulphate , homeostatic model assessment for insulin resistance , triglyceride , and cholesterol ( low-density lipoprotein , high-density lipoprotein , and total ) before and after the intervention were evaluated and compared as outcome measures . Fasting insulin ( p = .024 ) and homeostatic model assessment for insulin resistance ( p = .014 ) were reduced after 12 weeks in the cinnamon group compared with the placebo . There was also a significant decrease in low-density lipoprotein in cinnamon group ( p = .004 ) as compared with baseline that caused significant difference with placebo ( p = .049 ) . However , changes in other outcome measurements did not lead to statistically significant difference with placebo . The present results suggest that complementary supplementation of cinnamon significantly reduced fasting insulin and insulin resistance in women with PCOS OBJECTIVES Type 2 diabetes ( T2D ) may be caused by elevated oxidative stress , inflammation , and hyperglycemia . The phytochemicals in several herbal medicines are reported to effectively improve diabetes and to ameliorate diabetic complications . The aim of the present study was to determine the effects of cinnamon , cardamom , saffron , and ginger as supplementary remedies in T2D . METHODS This r and omized controlled , clinical trial included 204 T2D patients . The participants were r and omly assigned to four intervention groups receiving 3 glasses of black tea and either 3 g cardamom , or cinnamon , or ginger , or 1 g saffron and one control group which consumed only 3 tea glasses without any herbal medicine for 8 weeks . Markers of inflammation , oxidative stress , fasting blood sugar , lipid profile , and anthropometric measures were evaluated at baseline and after 8 weeks of intervention . RESULTS After 8 weeks of intervention , cinnamon , cardamom , ginger , and saffron consumption had significant effects on total cholesterol , LDL , and HDL levels ( p < 0.05 ) compared with controls . However , the herbal products did not have significant effects on measures of glycemic control , anthropometry , inflammation , and oxidative stress . In within-group comparisons only , cinnamon intake significantly decreased fasting blood sugar ( FBS ) . CONCLUSIONS The herbal remedies examined had significantly beneficial effects on cholesterol , but not on measures of glycemic control , oxidative stress , and inflammation . Based on the contradictory results reported in the literature , the effects of herbal medicine in diabetic patients should undergo further detailed investigation OBJECTIVE The objective of this study was to determine whether cinnamon improves blood glucose , triglyceride , total cholesterol , HDL cholesterol , and LDL cholesterol levels in people with type 2 diabetes . RESEARCH DESIGN AND METHODS A total of 60 people with type 2 diabetes , 30 men and 30 women aged 52.2 + /- 6.32 years , were divided r and omly into six groups . Groups 1 , 2 , and 3 consumed 1 , 3 , or 6 g of cinnamon daily , respectively , and groups 4 , 5 , and 6 were given placebo capsules corresponding to the number of capsules consumed for the three levels of cinnamon . The cinnamon was consumed for 40 days followed by a 20-day washout period . RESULTS After 40 days , all three levels of cinnamon reduced the mean fasting serum glucose ( 18 - 29 % ) , triglyceride ( 23 - 30 % ) , LDL cholesterol ( 7 - 27 % ) , and total cholesterol ( 12 - 26 % ) levels ; no significant changes were noted in the placebo groups . Changes in HDL cholesterol were not significant . CONCLUSIONS The results of this study demonstrate that intake of 1 , 3 , or 6 g of cinnamon per day reduces serum glucose , triglyceride , LDL cholesterol , and total cholesterol in people with type 2 diabetes and suggest that the inclusion of cinnamon in the diet of people with type 2 diabetes will reduce risk factors associated with diabetes and cardiovascular diseases
No statistically significant association was found between blood HDL-C changes and duration of supplementation .
CONCLUSION Cinnamon supplementation significantly reduced blood triglycerides and total cholesterol concentrations without any significant effect on LDL-C and
BACKGROUND Cinnamon is a rich botanical source of polyphenols , whose positive effects on blood lipid concentrations have been hypothesized , but have not been conclusively studied .
OBJECTIVE The objective of the study was to systematic ally review and evaluate the effect of administration of cinnamon on blood lipid concentrations .