Efficacy of standard (SLA) and modified sandblasted and acid-etched (SLActive) dental implants in promoting immediate and/or early occlusal loading protocols: a systematic review of prospective studies. Early loading after 21 days of healing of nonsubmerged titanium implants with a chemically modified sandblasted and acid-etched surface: two-year results of a prospective two-center study. Early loading at 21 days of non-submerged titanium implants with a chemically modified sandblasted and acid-etched surface: 3-year results of a prospective study in the posterior mandible. Early loading of nonsubmerged titanium implants with a chemically modified sand-blasted and acid-etched surface: 6-month results of a prospective case series study in the posterior mandible focusing on peri-implant crestal bone changes and implant stability quotient (ISQ) values. Early loading of sandblasted and acid-etched implants: a randomized-controlled double-blind split-mouth study. Five-year results. A randomized, 12-month controlled trial to evaluate non-inferiority of early compared to conventional loading of modSLA implants in single tooth gaps A prospective study evaluating a protocol for 6 weeks' loading of SLA implants in the posterior maxilla: one year results. Early loading of sandblasted and acid-etched titanium implants in the edentulous mandible: a prospective 5-year study. Early loading of non-submerged titanium implants with a sandblasted and acid-etched surface. 5-year results of a prospective study in partially edentulous patients. Prospective 10-year cohort study based on a randomized controlled trial (RCT) on implant-supported full-arch maxillary prostheses. Part 1: sandblasted and acid-etched implants and mucosal tissue. Early loading (2 or 6 weeks) of sandblasted and acid-etched (SLA) ITI implants in the posterior mandible. A 1-year randomized controlled clinical trial. A 5-year prospective multicenter study of early loaded titanium implants with a sandblasted and acid-etched surface. Early loading of sandblasted, acid-etched implants in the posterior maxilla and mandible: a 1-year follow-up report from a multicenter 3-year prospective study. Early loading of sandblasted and acid-etched (SLA) implants: a prospective split-mouth comparative study. Immediate loading of 2 interforaminal dental implants supporting an overdenture: clinical and radiographic results after 24 months. Immediate and early non-occlusal loading of Straumann implants with a chemically modified surface (SLActive) in the posterior mandible and maxilla: interim results from a prospective multicenter randomized-controlled study. The use of reduced healing times on ITI implants with a sandblasted and acid-etched (SLA) surface: early results from clinical trials on ITI SLA implants. Three-year data from a randomizd, controlled study of early loading of single-stage dental implants supporting maxillary full-arch prostheses. Enhanced implant stability with a chemically modified SLA surface: a randomized pilot study. Preliminary 3-dimensional surface texture measurement and early loading results with a microtextured implant surface. Immediate loading of implants with 3-unit fixed partial dentures: a 12-month clinical study.
OBJECTIVE To assess the survival percentage , clinical and radiographic outcomes of s and blasted and acid-etched ( SLA ) dental implants  and its modified surface ( SLActive ) in protocol s involving immediate and early occlusal loading . METHODS MEDLINE , EMBASE and the Cochrane Oral Health Group 's Trials Register CENTRAL were search ed in duplicate up to , and including , June 2013 to include r and omised controlled trials ( RCTs ) and prospect i ve observational studies of at least 6-month duration published in all language s. Studies limited to patients treated with SLA and /or SLActive implants involving a treatment protocol describing immediate and early loading of these implants were eligible for inclusion . Data on clinical and /or radiographic outcomes following implant placement were considered for inclusion . RESULTS Of the 447 potentially eligible publications identified by the search strategy , seven RCTs comprising a total of 853 implants ( 8 % titanium plasma-sprayed , 41.5 % SLA and 50.5 % SLActive ) and 12 prospect i ve observational studies including 1394 SLA and 145 SLActive implants  were included in this review . According to the Cochrane Collaboration 's tool for assessing risk of bias , one of the studies was considered to be at a low risk of bias , whereas the remaining studies were considered to be at an unclear risk . Regarding the observational studies , all of them presented a medium method ological quality based on the Modified Newcastle-Ottawa scale . There were no significant differences reported in the studies in relation to implant loss or clinical parameters between the immediate/early loading and delayed loading protocol s. Overall , 95 % of SLA and 97 % of SLActive implants  still survive at the end of follow-up . CONCLUSIONS Despite of the positive findings achieved by the included studies , few RCTs were available for analysis for SLActive implants . Study heterogeneity , scarcity of data and the lack of pooled estimates represent a limitation between studies ' comparisons and should be considered when interpreting the present findings PURPOSE The aim of this two-center study was to evaluate screw-type titanium implants with a chemically modified , s and blasted and acid-etched surface when placed in the posterior maxilla or m and ible , and loaded 21 days after placement . MATERIAL AND METHODS All 56 patients met strict inclusion criteria and provided informed consent . Each patient displayed either a single-tooth gap , an extended edentulous space , or a distal extension situation in the posterior m and ible or maxilla . Eighty-nine dental implants  ( SLActive , Institut Straumann AG , Basel , Switzerl and ) were inserted according to an established nonsubmerged protocol and underwent undisturbed healing for a period of 21 days . Where appropriate , the implants were loaded after 21 days of healing with provisional restorations in full occlusion . Definitive metal ceramic restorations were fabricated and positioned on each implant after 6 months of healing . Clinical measurements regarding soft tissue parameters and radiographs were obtained at different time points up to 24 months after implant placement . RESULTS Of the 89 inserted implants , two ( 2.2 % ) implants failed to integrate and were removed during healing , and two ( 2.2 % ) additional implants required a prolonged healing time . A total of 85 ( 95.6 % ) implants were therefore loaded without incident after 21 days of healing . No additional implant was lost throughout the study period , whereas one implant was lost to follow-up and therefore left unaccounted for further analysis . The remaining 86 implants all exhibited favorable radiographic and clinical findings . Based on strict success criteria , these implants were considered successfully integrated 2 years after insertion , result ing in a 2-year success rate of 97.7 % . CONCLUSION The results of this prospect i ve two-center study demonstrate that titanium implants with a modified SLA surface can predictably achieve successful tissue integration when loaded in full occlusion 21 days after placement . Integration could be maintained without incident for at least 2 years of follow-up BACKGROUND This study evaluates 3-year success rates of  titanium screw-type implants with a chemically modified s and blasted and acid-etched surface ( mod SLA ) , which were functionally loaded after 3 weeks of healing . METHODS A total of 56 implants , inserted in the posterior m and ibles of 39 partially edentulous patients , underwent undisturbed healing for 3 weeks . At day 21 , the implants were fully loaded with provisional crowns . Definitive metal ceramic restorations were fabricated after 6 months of healing . Clinical measurements regarding soft tissue parameters and radiographs were obtained at different time points up to 36 months after implant placement . The soft tissue and radiographic parameters for the mod SLA implants after 3 years in function were compared to a historic control group of implants with an SLA surface using an early loading protocol after 6 weeks . RESULTS None of the implants failed to integrate . However , two implants were considered " spinners " at day 21 and were left unloaded for an extended period . Therefore , 96.4 % of the inserted implants were loaded according to the protocol tested . All 56 implants , including the " spinners , " showed favorable clinical and radiographic findings at the 3-year follow-up examination . All 56 implants were considered successfully integrated , result ing in a 3-year survival and success rate of 100 % . Dental implants with a mod SLA surface demonstrated statistically significant differences for probing depths and clinical attachment level values compared to the historic control group , with the mod SLA surface implants having overall lower probing depths and clinical attachment level scores . CONCLUSION This prospect i ve study using an early loading protocol demonstrates that titanium implants with the mod SLA surface can achieve and maintain successful tissue integration over a period of 3 years PURPOSE The aim of this prospect i ve case series study was to evaluate the short-term success rates of  titanium screw-type implants  with a chemically modified s and -blasted and acid-etched ( mod SLA ) surface after 3 weeks of healing . MATERIAL AND METHODS A total of 56 implants were inserted in the posterior m and ible of 40 partially edentulous patients exhibiting bone densities of class I to III . After a healing period of 3 weeks , all implants were functionally loaded with a screw-retained crown or fixed dental prosthesis . The patients were recalled at weeks 4 , 7 , 12 , and 26 for monitoring and assessment of clinical and radiological parameters , including implant stability quotient ( ISQ ) measurements . RESULTS None of the implants failed to integrate . However , two implants were considered " spinners " at day 21 and left unloaded for an extended period . Therefore , 96.4 % of the inserted implants were loaded according to the protocol tested . All 56 implants including the " spinners " showed favorable clinical and radiographic findings at the 6-month follow-up examination . The ISQ values increased steadily throughout the follow-up period . At the time of implant placement , the range of ISQ values exhibited a mean of 74.33 , and by week 26 , a mean value of 83.82 was recorded . Based on strict criteria , all 56 implants were considered successfully integrated , result ing in a 6-month survival and success rate of 100.0 % . CONCLUSION This prospect i ve study using an early-loading protocol after 3 weeks of healing demonstrated that titanium implants with the modified SLA surface can achieve and maintain successful tissue integration over a period of at least 6 months . The ISQ method seems feasible to monitor implant stability during the initial wound-healing period OBJECTIVES The aim of the present split-mouth study is to assess the peri-implant conditions around early-loaded s and blasted and acid-etched ( SLA ) implants , 5 years after abutment connection and to compare , in the same patients , the results obtained with a st and ard protocol using identical implants with a TPS surface . MATERIAL AND METHODS Surgical procedure was performed by the same operator and was identical at test ( SLA ) and control ( TPS ) sites , in 32 healthy patients . Abutment connection was carried out at 35 N cm 6 weeks postsurgery for test sites and 12 weeks for the controls . Patients were seen regularly , for control and professional cleaning . At 60 months , clinical measures and radiographic bone changes were recorded by the same operator , blind to the type of surface of the implant , on 27 patients , as five patients were lost to follow-up . RESULTS A total number of 106 implants were examined . No implant was lost . No significant differences were found with respect to the presence of plaque [ modified plaque index ( mPI ) 0.27+/-0.56 vs. 0.32+/-0.54 ] , bleeding on probing ( 29 % vs. 32 % ) , mean pocket depth ( 3.2+/-1 vs. 3.2+/-1 mm ) or mean marginal bone loss ( 0.32+/-1.04 vs. 0.44+/-1.12 mm ) between test and control . Four implants that presented ' spinning ' at the time of abutment connection presented no significant differences from the rest of the test sites . CONCLUSION The results of this prospect i ve study confirm that SLA implants , under defined conditions , are suitable for early loading at 6 weeks in both the m and ible and the maxilla . Limited implant spinning , occasionally found at abutment connection , produces no detrimental effect on the clinical outcome when properly h and led Background The aim of the study was to evaluate whether early loading of implants with a chemically modified s and blasted , large-grit , acid-etched ( SLA ) ( SLActive ® ) surface was non-inferior to conventional loading in terms of change in crestal bone level . Methods This was a r and omized , controlled , multicenter study . Patients requiring single-tooth rehabilitation in the posterior maxilla or m and ible received implants and were r and omized to receive a provisional restoration in occlusal load after 25 ± 3 days ( early loading ) or after 13 ± 1 weeks ( conventional loading ) . The primary endpoint was change in crestal bone level between implant placement ( baseline ) and 6 months . Secondary endpoints included change in crestal bone level between baseline and 12 months , implant survival and success rates , and patient satisfaction . Results Of the 84 patients enrolled , 78 received implants  and were r and omized onto the  early loading ( 41 patients ) and  conventional loading ( 37 patients ) groups . The mean change in crestal bone level between baseline and 6 months was 0.56 ± 0.58 and 0.51 ± 0.62 mm for early and conventional loading , respectively ; at 12 months , the mean change was 0.76 ± 0.60 and 0.73 ± 0.77 mm , respectively . Implant survival and success at 12 months were 100 % for both groups . Patient satisfaction was similar between the groups , except that more patients in the early loading group were satisfied or highly satisfied with the time taken for fitting . Conclusion The study demonstrated that early implant loading was non-inferior to conventional implant loading in terms of crestal bone level change in a Japanese patient population in short follow-up period and single tooth gaps in molar regions Experimental and clinical studies have shown that modification of implant surfaces can result in increased bone-to-implant contact at earlier times thus reducing the healing period between surgery and prosthesis . S and blasted and acid-etched ( SLA ) implants are in this category and have successfully undergone early loading in patients with good bone quality and quantity . Nevertheless , premature loading of SLA implants was not routinely possible in predominantly trabecular bone , such as the posterior maxilla , as it is often characterized by a deficiency in initial bone to implant contact . The purpose of this prospect i ve clinical investigation is to evaluate the efficacy of a modified surgical protocol followed by loading SLA implants at 6 weeks in the posterior maxilla . Drilling was limited to the minimum , and most of the site preparation was produced with osteotomes . Screw tapping was never performed and primary stability was always achieved . Abutment connection was carried out at 15 Ncm 43 ( + /- 1 ) days after surgery and provisional restoration was fabricated . Further abutment tightening at 35 Ncm was performed after an additional 6 weeks . Of the 36 SLA implants placed in 19 patients , one was lost before final restoration .  Clinical and radiographic measures were taken at baseline and 1 year postoperatively . The preliminary results suggest that , by means of the surgical and restorative technique presented , SLA implants are suitable for loading at 6 weeks in the posterior maxilla . More years of observation will verify whether osseointegration can be equally maintained over a long period PURPOSE The aim of this prospect i ve cohort study was to determine the 5-year implant survival and success rates associated with early loading ( 6 weeks after nonsubmerged placement ) of s and blasted and acid-etched ( SLA ) Straumann implants in the edentulous m and ible . A secondary objective was to determine the peri-implant tissue response and measure alterations in peri-implant crestal bone levels . MATERIAL S AND METHODS SLA implants were placed and primarily loaded 6 weeks later with 35 Ncm during abutment placement . The peri-implant bone and mucosal conditions of the participants were monitored radiographically and clinical ly over a 5-year period . RESULTS Fourteen patients received 60 implants . Thirteen patients and 54 implants were examined at the 5-year appointment . Two of 60 implants failed during the healing period , and four implants were lost during follow-up and considered as dropouts . The remaining implants showed favorable clinical and radiographic findings and were considered successfully integrated at the 5-year examination . The mean loss of crestal bone height after 5 years was 0.77 mm ( SEM 0.09 ) . This result ed in a 5-year cumulative success rate of 96.7 % . CONCLUSION In this prospect i ve study , the early loading of  Straumann implants with the SLA surface in the edentulous m and ible after a healing time of 6 weeks provided successful osseointegration with high predictability . Successful integration was maintained for 5 years OBJECTIVES The aim of this prospect i ve cohort study was to evaluate the success rate of titanium screw-type implants with the s and blasted and acid-etched ( SLA ) surface loaded early , after 6 weeks of healing . MATERIAL AND METHODS A total of 104 implants were inserted into posterior sites of 51 partially edentulous patients exhibiting bone densities of class I-III . After a healing period of 6 weeks , all implants were functionally loaded with cemented crowns or fixed partial dentures . The patients were recalled at 3 , 12 , 24 , 36 , 48 and 60 months for clinical and radiographic examination . RESULTS One implant failed to integrate during healing , and three implants were lost to follow-up and were considered drop-outs . The remaining 100 implants showed favorable clinical and radiographic findings at the 5-year examination . The peri-implant soft tissues were stable over time ; the mean probing depths and mean attachment levels did not change during the follow-up period . None of the radiographs exhibited signs of continuous peri-implant radiolucency , which confirmed ankylotic stability for all 100 implants . The measurement of the bone crest levels ( DIB values ) indicated stability as well . Based on strict success criteria , all 100 implants were considered successfully integrated , result ing in a 5-year success rate of 99 % . CONCLUSION This prospect i ve study using an early loading protocol with 6 weeks of healing demonstrated that titanium implants with the SLA surface can achieve and maintain successful tissue integration with high predictability for at least 5 years of follow-up in selected patients and sites BACKGROUND There have been very few long-term controlled studies ( i.e. , over 5 years duration ) focusing on marginal conditions for implants with a s and blasted , large grit , and acid-etched ( SLA ) surface . PURPOSE To evaluate and report 10-year data on outcomes of  implants with an SLA surface placed in the edentulous maxilla . MATERIAL S AND METHODS In a r and omized controlled trial ( RCT ) cohort of 24 patients , the outcomes of implants with an SLA surface were registered . The RCT cohort has previously been reported after 1 year , 3 years , and 5 years of loading . RESULTS One patient dropped out of the study prior to the 10-year control . Of the 23 remaining patients , the implant survival rate was 95.1 % . If implants of unknown status were also considered lost , that is , one drop-out patient with three implants for whom no information could be obtained , the implant survival rate was 93 % . The mean marginal bone loss from baseline ( 139 implants ) to 10 years ( 102 implants ) was 1.07 mm ( st and ard deviation 0.98 ) . One implant out of 102 available for radiographic examination according to the original protocol showed a bone loss exceeding 4 mm . Of the 84 implants available for clinical examination , none showed a Plaque Index or sulcus bleeding index of 3 . The mean implant stability quotient was significantly higher for mesial-distal versus buccal-palatal measurements . CONCLUSION The implant survival was 95.1 % . The mean value of bone loss after 10 years was 1.07 mm . Peri-implantitis were noted at the 5-year follow-up for one patient with a previous history of periodontitis ; this patient did not attend the 10-year follow-up . This study shows that s and blasted and acid-etched implants offers predictable long-term results as support for full-arch maxillary prostheses UNLABELLED The aim of this 1-year prospect i ve controlled clinical trial was to evaluate the effect of early loading of ITI solid screw titanium implants with a s and blasted and acid-etched ( SLA ) surface on clinical and radiographic parameters . MATERIAL AND METHODS Twenty-seven consecutively admitted patients presenting bilateral edentulous posterior m and ibular areas and in need of prosthetic reconstruction were recruited . Sixty-seven ITI st and ard solid screw implants with an SLA surface , a diameter of 4.1 mm and a length of 8 , 10 or 12 mm were installed bilaterally in molar and premolar areas according to a one-stage surgical protocol . One week ( test ) and 5 weeks ( control ) after implant placement , solid ITI prosthetic abutments were connected using a torque of 35 N cm . No provisional restoration was fabricated . Two weeks ( test ) and 6 weeks ( control ) after implant placement , porcelain-fused-to-metal single-tooth crowns were cemented . Clinical measurements were obtained at day 0 and 2 , 6 , 12 , 24 and 52 weeks thereafter . Periapical radiographs were taken immediately after implant placement , after 6 weeks and at the 1-year examination . RESULTS After 1 year , implant survival was 100 % . Two test and one control implants rotated at the time of abutment connection and were left unloaded for 12 additional weeks . At the 1-year examination , no statistically significant differences were found between the test and control sites with respect to pocket probing depths ( 2.6 mm + /- 0.5 vs. 2.7 mm + /- 0.5 ) , mean clinical attachment levels ( 3.1 mm + /- 0.4 vs. 3.2 mm + /- 0.5 ) , mean percentages of sites bleeding on probing ( 9.7 % vs. 8.3 % ) , mean widths of keratinized mucosa ( 1.8 mm + /- 0.4 vs. 1.9 mm + /- 0.5 ) , mean PerioTest values ( -1.4 PTV + /- 0.9 vs. -1.6 PTV + /- 0.8 ) or mean crestal bone loss measurements ( 0.57 mm + /- 0.49 vs. 0.72 mm + /- 0.50 ) . CONCLUSION Based on these results , loading of titanium implants with an SLA surface as early as 2 weeks did not appear to jeopardize the osseointegration healing process in the posterior m and ible . Furthermore , implants rotating at 35 N cm , if left unloaded for additional 12 weeks , did not negatively affect clinical and radiographic outcomes PURPOSE For dental implants to be successful , osseointegration must occur , but it is unknown how much time must pass for osseointegration to be established . Pre clinical studies suggested that titanium implants with a s and blasted and acid-etched ( SLA ) surface were more osteoconductive and allowed more rapid osseointegration than machined or turned implant surfaces . The hypothesis of this study was that implants with an SLA surface could be loaded in half the conventional healing time of machined-surface implants and that , after loading , the implants would be successful for 5 years . MATERIAL S AND METHODS A prospect i ve multicenter clinical study was conducted with 439 implants placed in native bone in 135 edentulous and partially edentulous patients . Abutments were attached to the implant with 35 Ncm of torque without countertorque after 6 weeks in type I to III bone and after 12 weeks in type IV bone . The patients were carefully evaluated for 5 years . RESULTS Most implants were placed in nonsmoking , nondiabetic patients with a mean age of 55 years ( range , 21 to 82 years ) . Eighty percent of the implants were 10 or 12 mm long , 96 % had a diameter of 4.1 mm , and 78 % were placed in type II or III bone . Patients maintained good oral hygiene and were satisfied with the restorations . Four implants failed , and one implant was deemed unsuccessful between surgery and the 1-year postloading visit . No implants failed or were unsuccessful in subsequent years . The cumulative survival and success rates for 385 implants in 120 patients after 5 years were 99.1 % and 98.8 % , respectively . CONCLUSION Implants with an SLA surface can be restored in 6 weeks for type I to III bone and 12 weeks for type IV bone . Furthermore , they can be maintained after loading for 5 years with very high success and survival rates PURPOSE The aim of the present study was to evaluate the concept of an immediate loading protocol in the posterior maxilla and m and ible through analysis of implant survival at 1 year . MATERIAL S AND METHODS One year follow-up data of a multicenter study are reported . Eighty-two ITI s and blasted , acid-etched ( SLA ) implants in 40 patients were loaded between 0 and 11 days after implant placement ( mean 4.3 + /- 2.8 days ) . The restorations consisted of either 2 splinted crowns or a 3-unit fixed prosthesis . All restorations were put into full functional occlusion . Periapical radiographs were evaluated for changes in crestal bone level from baseline to 1 year postloading . Primary stability of the implants was checked initially and before the fitting of the definitive prosthesis . The restorations were evaluated by the practitioners for retention , stability , and esthetics . RESULTS Three patients ' implants were not loaded because of lack of primary stability , and a fourth patient was excluded from the study because of a protocol violation ( more than 4 implants were used ) . All 4 patients were successfully treated outside the protocol . The overall survival rate of the remaining implants at 1 year was 98.8 % . The mean bone loss at 1 year was 0.52 + /- 0.98 mm , which is within the reported limits of less than 1 mm ( range 0.4 to 1.4 mm ) loss in the first year . DISCUSSION AND CONCLUSION The early results from this study indicate that early and immediate loading of 2 implants in the posterior maxilla and m and ible may be suitable in selected patients . On the basis of 1 year of observation , the results appear similar to those achieved with a delayed procedure S and blasted and acid-etched ( SLA ) implants were recently introduced to reduce the healing period between surgery and prosthesis . In this split-mouth study , SLA implants were compared to titanium plasma-sprayed ( TPS ) implants under loaded conditions one year after placement in 32 healthy patients , with comparable bilateral edentulous sites and no discrepancies in the opposing dentition . The surgical procedure was performed by the same operator and was identical at 68 SLA ( test ) and 68 TPS ( control ) sites . Tapping was never performed and primary stability was always achieved . Abutment connection was carried out at 35 Ncm 6 weeks postsurgery for test sites and 12 weeks for the controls , by the same dentist blind to the type of surface of the implant . In 4 of the 68 test sites the implant rotated slightly , patients reported minor pain and connection was not completed . Provisional restoration was fabricated and a new tightening was performed after six weeks . Similar gold-ceramic restorations were cemented on the same type of solid abutments on both sites . No implant was lost . Clinical measures and radiographic changes were recorded by the same operator , blind to the type of surface of the implant , 1 year post surgery . No significant differences were found with respect to presence of plaque ( 24 % vs. 27 % ) , bleeding on probing ( 24 % vs. 31 % ) , mean pocket depth ( 3.3 mm vs. 2.9 mm ) or mean marginal bone loss ( 0.65 mm vs. 0.77 mm ) . The results suggest that SLA implants are suitable for early loading at 6 weeks . Limited implant spinning may occasionally be found but , if properly h and led , it produces no detrimental effect on the clinical outcome PURPOSE In this study , preliminary results of immediate loading of ITI s and blasted , large-grit , acid-etched ( SLA ) implants with a bar-connected overdenture in the edentulous m and ible are presented . MATERIAL S AND METHODS Ten edentulous patients between 48 and 74 years old were included in this study . All patients received 2 SLA-surfaced ITI solid-screw dental implants in the interforaminal region , which were loaded with a bar connector and an overdenture 1 day after implant placement . Marginal bone resorption was evaluated using periapical radiographs . Gingival health ( ie , Bleeding Index ) and patient satisfaction ( measured using a visual analog scale ) were evaluated . Follow-up time was 24 to 36 months ( mean time 29.8 months ) after implant loading . RESULTS Twenty-four months after placement , none of the 20 implants had failed . Marginal bone resorption around all implants after 12 months averaged 0.71 mm , and 92 % of the sites had a Bleeding Index of 0 . Between 12 and 24 months , average bone resorption was an additional 0.08 mm . All patients demonstrated an improved quality of life . DISCUSSION The amount of bone resorption was comparable to amounts reported in studies with st and ard loading times . The low rate of inflammation of the peri-implant soft tissue and the high level of patient satisfaction in this study demonstrate encouraging short-term results . CONCLUSION The results suggest that immediate loading of 2 dental implants can be successful and further support the use of a rough implant surface in residual bone OBJECTIVE Immediate and early loading of dental implants can simplify treatment and increase overall patient satisfaction . The purpose of this 3-year prospect i ve r and omized-controlled multicenter study was to assess the differences in survival rates and bone level changes between immediately and early-loaded implants with a new chemically modified surface ( SLActive ) . This investigation shows interim results obtained after 5 months . MATERIAL AND METHODS Patients > or = 18 years of age missing at least one tooth in the posterior maxilla or m and ible were enrolled in the study . Following implant placement , patients received a temporary restoration either on the day of surgery ( immediate loading ) or 28 - 34 days after surgery ( early loading ) ; restorations consisted of single crowns or two to four unit fixed dental prostheses . Permanent restorations were placed 20 - 23 weeks following surgery . The primary efficacy variable was change in bone level ( assessed by st and ardized radiographs ) from baseline to 5 months ; secondary variables included implant survival and success rates . RESULTS A total of 266 patients were enrolled ( 118 males and 148 females ) , and a total of 383 implants were placed ( 197 and 186 in the immediate and early loading groups , respectively ) . Mean patient age was 46.3+/-12.8 years . After 5 months , implant survival rates were 98 % in the immediate group and 97 % in the early group . Mean bone level change from baseline was 0.81+/-0.89 mm in the immediate group and 0.56+/-0.73 mm in the early group ( P<0.05 ) . Statistical analysis revealed a significant center effect ( P<0.0001 ) and a significant treatment x center interaction ( P=0.008 ) . CONCLUSIONS The results suggested that Straumann implants with an SLActive can be used predictably in time-critical ( early or immediate ) loading treatment protocol s when appropriate patient selection criteria are observed . The mean bone level changes observed from baseline to 5 months ( 0.56 and 0.81 mm ) corresponded to physiological observations from other studies , i.e. , were not clinical ly significant . The presence of a significant center effect and treatment x center interaction indicated that the differences in bone level changes between the two groups were center dependent ITI dental implants are available with two bone-anchoring surfaces , a titanium plasma-sprayed ( TPS ) surface , and a recently introduced s and blasted and acid-etched ( SLA ) surface . Cell culture and animal tests demonstrate that the SLA surface stimulates bone cell differentiation and protein production , has large amounts of bone-to-implant contact , and results in large removal torque values in functional testing of the bone contact . As a result of these studies , a prospect i ve human clinical trial was initiated to determine whether the 4.1 mm diameter SLA ITI solid screw implants could be predictably and safely restored as early as six weeks after implant placement surgery . The protocol restricted the use of the reduced healing time to a ) healthy patients with sufficient bone volume to surround the implant , and b ) those patients who had good bone quality ( classes I-III ) at the implant recipient site . Patients with poorer bone quality ( class IV ) did not have restorations until 12 weeks after implant placement . The clinical trial is an ongoing multicenter trial , with six centers in four countries , and with follow-up over five years . The primary outcome variable was abutment placement with a 35 Ncm force , with no countertorque and no pain or rotation of the implant . A secondary outcome was implant success , as defined by no mobility , no persistent pain or infection , and no peri-implant radiolucency . To date , 110 patients with 326 implants have completed the one-year post-loading recall visit , while 47 patients with 138 implants have completed the two-year recall . Three implants were lost prior to abutment connection . Prosthetic restoration was commenced after shortened healing times on 307 implants . The success rate for these implants , as judged by abutment placement , was 99.3 % ( with an average healing time of 49 days ) . Life table analyses demonstrated an implant success rate of 99.1 % , both for 329 implants at one year and for 138 implants at two years . In the 24-month period after restoration , no implant losses were reported for the 138 implants . These results demonstrate that , under defined conditions , solid screw ITI implants with an SLA endosseous surface can be restored after approximately six weeks of healing with a high predictability of success , defined by abutment placement at 35 Ncm without countertorque , and with subsequent implant success rates of greater than 99 % two years after restoration PURPOSE The aim of this 3-year r and omized controlled trial ( RCT ) was to compare biologic and technical treatment outcomes and patient satisfaction after early ( < or = 14 days postimplantation ) loaded implants with those of implants loaded after a healing period of 3 to 4 months in the edentulous maxilla . MATERIAL S AND METHODS Twenty-four patients with completely edentulous maxillae were r and omized into a test group ( n = 16 ) and a control group ( n = 8) . All patients received 5 or 6 solid screw-type titanium implants with s and blasted , large-grit , acid-etched ( SLA ) surfaces . In total , 142 implants were placed and 139 implants were loaded with full-arch prostheses  . Clinical assessment s were obtained at loading and after 3 , 6 , 12 , 24 , and 36 months . Radiographs of implants and existing teeth were taken at loading ; after 6 , 12 , 24 , and 36 months ; and at 12 , 24 , and 36 months , respectively . RESULTS The cumulative implant success rate 3 years after loading was 100 % . At the 3-year examination the mean ( P < or = .005 ) , distal ( P < or = .005 ) , and mesial ( P > .05 ) crestal bone levels were better in the test group . No significant differences between the test and control groups were noted for any other outcome measure . The most common adverse event in both groups was tooth-crown fracture . DISCUSSION A review of the literature , both printed and electronic , revealed no study fulfilling the criteria of an RCT dealing with the early loading of maxillary full-arch prostheses . This study fulfills those criteria . CONCLUSION In this study population it has been concluded that the early ( approximately 2 weeks ) loading protocol is a viable alternative to the st and ard ( 3 to 4 months ) protocol in the rehabilitation of a completely edentulous maxilla with a complete implant-supported fixed prosthesis PURPOSE Chemical modification to a s and blasted , large-grit , acid-etched ( SLA ) implant surface has been shown to enhance the rate of osseointegration . The goal of the present study was to examine changes in stability for implants with a chemically modified SLA surface and to compare their outcomes to those of control implants . MATERIAL S AND METHODS A r and omized controlled trial was conducted with 31 patients . Each patient received 2 implants with the same physical properties but with surfaces that were chemically different . The control implants had a st and ard SLA surface , while the test implants had a chemically modified surface . Resonance frequency analysis was assessed weekly over the first 6 weeks following implant placement . RESULTS All implants proved clinical ly successful , allowing for restoration . Most implants were placed in the m and ible ( 50 of 62 ) . A shift in implant stability from decreasing stability to increasing stability ( P < .001 ) , occurred after 2 weeks for the test implants and after 4 weeks for the control implants . CONCLUSION The findings from this pilot study provide clinical support for the potential for chemical modification of the SLA surface to alter biologic events during the osseointegration process and demonstrate levels of short-term clinical success similar to those observed for implants with an SLA surface PURPOSE This investigation was conducted to obtain preliminary roughness data on a microtextured implant surface and to determine its ability to sustain a 1-stage surgical procedure and early full occlusal loading of single-tooth restorations in humans . MATERIAL S AND METHODS Three-dimensional ( 3D ) vertical scanning interferometry was conducted on sample s of the test surface ( MTX ) and 2 control surfaces ( Osseotite and s and blasted/acid-etched [ SLA ] ) . Test implants were also placed in vivo , restored with fully occluding single-tooth restorations ( n = 27 ) after 2 months of nonsubmerged healing , and clinical ly monitored for 48 months of follow-up . RESULTS Microtexture was relatively uniform on the test surface and more r and om and irregular on the control surfaces . MTX and Osseotite were similar in some roughness parameters , but the MTX surface had a greater number of micropits that were spaced closer together ( Stylus Y lambda q ) and with higher slope values ( Stylus Y delta q ) . Cumulative life table results were 100 % for all MTX implants placed in maxillary and m and ibular jaw locations , and no discernible marginal bone changes were observed . Overall implant success was 100 % after 4 years of clinical functioning . DISCUSSION The findings of this study appear promising but should be considered preliminary , because of the limitations in the number of locations measured on each product sample and the small number of implants clinical ly studied . CONCLUSION Within the scope of the present study , MTX implants exhibited a uniform micropitted surface , as well as 100 % survival and 100 % clinical success after nonsubmerged placement , early loading with single-tooth restorations at 2 months , and 48 months of clinical functioning . ( More than 50 references . PURPOSE The aim of the present clinical trial was to evaluate the 12-month success rate of titanium dental implants placed in the posterior m and ible and immediately loaded with 3-unit fixed partial dentures . MATERIAL S AND METHODS Patients with missing m and ibular premolars and molars were enrolled in this study . To be included in the study , the implants had to show good primary stability . Implant stability was measured with resonance frequency analysis using the Osstell device ( Integration Diagnostics ) . Implants were included in the study when the stability quotient ( ISQ ) exceeded 62 . Clinical measurements , such as width of keratinized tissue , ISQ , and radiographic assessment of peri-implant bone crest levels , were performed at baseline and at the 12-month follow-up . The comparison between the baseline and the 12-month visits was performed with the Student t test for paired data ( statistically significant at a level of alpha = 0.05 ) . RESULTS Forty implants with a s and blasted , large grit , acid-etched ( SLA ) surface ( Straumann ) were placed in 20 patients . At 12 months , only 1 implant had been lost because of an acute infection . The remaining 39 implants were successful , result ing in a 1-year success rate of 97.5 % . Neither peri-implant bone levels , measured radiographically , nor implant stability changed significantly from baseline to the 12-month follow-up ( P > .05 ) . DISCUSSION The immediate functional loading of implants placed in this case series study result ed in a satisfactory success rate . CONCLUSION The findings from this clinical study showed that the placement of SLA transmucosal implants in the m and ibular area and their immediate loading with 3-unit fixed partial dentures may be a safe and successful procedure
Despite of the positive findings achieved by the included studies , few RCTs were available for analysis for SLActive implants .
OBJECTIVE To assess the survival percentage , clinical and radiographic outcomes of s and blasted and acid-etched ( SLA ) dental implants  and its modified surface ( SLActive ) in protocol s involving immediate and early occlusal loading .