Mobile.net: Mobile Telephone Text Messages to Encourage Adherence to Medication and to Follow up With People With Psychosis: Methods and Protocol for a Multicenter Randomized Controlled Two-Armed Trial A Clinical Trial to Test the Feasibility of a Telehealth Psychoeducational Intervention for Persons With Schizophrenia and Their Families: Intervention and 3-Month Findings. Web-based psychoeducational intervention for persons with schizophrenia and their supporters: one-year outcomes. A proof of concept trial of an online psychoeducational program for relatives of both veterans and civilians living with schizophrenia. Safety and privacy outcomes from a moderated online social therapy for young people with first-episode psychosis. Connecting the dots: Twenty-first century technologies to tackle twenty-first century challenges in early intervention Patterns of usual care for schizophrenia: initial results from the Schizophrenia Patient Outcomes Research Team (PORT) Client Survey.
Background Schizophrenia is a high-cost , chronic , serious mental illness . There is a clear need to improve treatments and exp and access to care for persons with schizophrenia , but simple , tailored interventions are missing . Objective To evaluate the impact of tailored mobile telephone text messages to encourage adherence to medication and to follow up with people with psychosis at 12 months . Methods Mobile . Net is a pragmatic r and omized trial with inpatient psychiatric wards allocated to two parallel arms . The trial will include 24 sites and 45 psychiatric hospital wards providing inpatient care in Finl and . The participants will be adult patients aged 18–65 years , of either sex , with antipsychotic medication ( Anatomical Therapeutic Chemical classification 2011 ) on discharge from a psychiatric hospital , who have a mobile phone , are able to use the Finnish language , and are able to give written informed consent to participate in the study . The intervention group will receive semiautomatic system ( short message service [ SMS ] ) messages after they have been discharged from the psychiatric hospital . Patients will choose the form , content , timing , and frequency of the SMS messages related to their medication , keeping appointments , and other daily care . SMS messages will continue to the end of the study period ( 12 months ) or until participants no longer want to receive the messages . Patients will be encouraged to contact research ers if they feel that they need to adjust the message in any way . At all times , both groups will receive usual care at the discretion of their team ( psychiatry and nursing ) . The primary outcomes are service use and healthy days by 12 months based on routine data ( admission to a psychiatric hospital , time to next hospitalization , time in hospital during this year , and healthy days ) . The secondary outcomes are service use , coercive measures , medication , adverse events , satisfaction with care , the intervention , and the trial , social functioning , and economic factors . Data will be collected 12 months after baseline . The outcomes are based on the national health registers and patients ’ subjective evaluations . The primary analysis will be by intention-to-treat . Trial Registration International St and ard R and omised Controlled Trial Number ( IS RCT N ) : 27704027 ; http://www.controlled-trials.com/IS RCT N27704027 ( Archived by WebCite at http://www.webcitation.org/69FkM4vcq OBJECTIVE To evaluate the feasibility of a telehealth psychoeducation intervention for persons with schizophrenia and their family members . STUDY DESIGN R and omized controlled trial . PARTICIPANTS 30 persons with schizophrenia and 21 family members or other informal support persons . INTERVENTIONS Web-based psychoeducation program that provided online group therapy and education . MAIN OUTCOME MEASURES Measures for persons with schizophrenia included perceived stress and perceived social support ; for family members , they included disease-related distress and perceived social support . RESULTS At 3 months , participants with schizophrenia in the intervention group reported lower perceived stress ( p = .04 ) and showed a trend for a higher perceived level of social support ( p = .06 ) . CONCLUSIONS The findings demonstrate the feasibility and impact of providing telehealth-based psychosocial treatments , including online therapy groups , to persons with schizophrenia and their families OBJECTIVE This study examined the use of a uniquely design ed Web site and home computers to deliver online multifamily psychoeducational therapy to persons with schizophrenia and their informal supports ( family and friends ) . Web site usage and outcome benefits are reported . METHODS Thirty-one persons with schizophrenia or schizoaffective disorder and 24 support persons were r and omly assigned to the online intervention ( telehealth ) or treatment as usual ( usual care ) condition . At three , six , and 12 months , interviewer-administered assessment s were conducted with participants . Intention-to-treat analyses compared persons with schizophrenia in the two study conditions on severity of positive symptoms and knowledge of schizophrenia . Support persons in the two study conditions were compared on knowledge of schizophrenia . Each participant 's usage of the Web site was logged . RESULTS Persons with schizophrenia in the telehealth condition had a large and significant reduction in positive symptoms ( p=.042 , d=-.88 ) and a large and significant increase in knowledge of schizophrenia compared with their counterparts in the usual care condition . Support persons in the telehealth condition showed a large and significant increase in knowledge about prognosis compared with those in the usual care condition ( p=.036 , d=1.94 ) . Persons with schizophrenia used the Web site to a much greater extent ( pages viewed and time spent ) than support persons . CONCLUSIONS These findings suggest that online delivery of psychotherapeutic treatment and educational re sources to consumers ' homes has considerable potential to improve consumer well-being and offers several advantages over st and ard clinic-based delivery models OBJECTIVES Family psychoeducation has been found to reduce relapse in schizophrenia but penetration rates are low . In this study , we evaluate the feasibility of an online multifamily group program for relatives of persons with schizophrenia that can be accessed from participants ' homes . METHODS We explored participation rates and evaluations of a 12-month multimodal website intervention . Using a quasi-experimental design , we compared illness outcomes ( factors on the Brief Psychiatric Rating Scale , hospitalizations ) of persons with diagnosed schizophrenia , and relative distress outcomes ( somatic concerns and anxiety/depression subscales on the Brief Symptom Inventory ) from relatives participating in the intervention ( n = 26 ) to archival data we had from comparable dyads who received customary care ( n = 16 ) . RESULTS The majority of participants in the program attended more than half the core online support sessions , expressed high levels of satisfaction , and found the technology easy to access . There appeared to be little impact of online participation on clinical status of persons with schizophrenia or relatives ' distress , although there was a trend for fewer hospitalizations in the online group . Small sample size is a factor in interpreting results . CONCLUSIONS Online interventions for relatives of persons with schizophrenia , while feasible , present unique challenges . These include 1 ) assuring access to the intervention in population s who do not own a computer ; 2 ) addressing privacy concerns ; 3 ) overcoming the special challenges of conducting groups in real time ; 4 ) managing emergent situations adequately ; and 5 ) questions about efficacy OBJECTIVE Internet-based treatments for early psychosis offer considerable promise , but safety and security need to be established . This study pilot tested Horyzons , a novel online treatment application that integrates purpose -built moderated social networking with psychoeducation for recovery from early psychosis . METHODS Safety , privacy , and security were evaluated during a one-month single-group trial with 20 young consumers recovering from early psychosis who were recruited in Melbourne , Australia . Known clinical risk factors informed the safety protocol . Safety , privacy , and security were evaluated with respect to relapse and self-harm , users ' perceptions of safety and privacy , and activity using Horyzons . RESULTS No clinical or security problems with use of Horyzons were noted . Participants described feeling safe and trusting Horyzons . CONCLUSIONS Private moderated online social networking combined with psychoeducation was a safe and secure therapeutic environment for consumers recovering from a first episode of psychosis . Testing the intervention in a r and omized controlled trial is warranted Bromberger JT and Kravitz HM ( 2011 ) Mood and menopause : Findings from the Study of Women ’s Health Across the Nation ( SWAN ) over 10 years . Obstetrics and Gynecology Clinics of North America 38 : 609–625 . Bou Khalil R ( 2012 ) Biological correlates of women ’s mood and orgasm . Australian and New Zeal and Journal of Psychiatry 46 : 1115–1117 . Christensen BS , Grønbaek M , Osler M , et al. ( 2011 ) Sexual dysfunctions and difficulties in Denmark : Prevalence and associated sociodemographic factors . Archives of Sexual Behavior 40 : 121–132 . Davis S , Papalia MA , Norman RJ , et al. ( 2008 ) Safety and efficacy of a testosterone metered-dose transdermal spray for treating decreased sexual satisfaction in premenopausal women : A r and omized trial . Annals of Internal Medicine 148 : 569–577 . Davis SR and Jane F ( 2011 ) Sex and perimenopause . Australian Family Physician 40 : 274–278 . Davison SL , Bell RJ , LaChina M , et al. ( 2009 ) The relationship between self-reported sexual satisfaction and general well-being in women . The Journal of Sexual Medicine 6 : 2690–2697 . Haberfellner EM and Rittmannsberger H ( 2004 ) Spontaneous remission of SSRI-induced orgasm delay . Pharmacopsychiatry 37 : 127–130 . Montejo AL , Llorca G , Izquierdo JA , et al. ( 2001 ) Incidence of sexual dysfunction associated with antidepressant agents : A prospect i ve multicenter study of 1022 out patients . Spanish Working Group for the Study of Psychotropic-Related Sexual Dysfunction . Journal of Clinical Psychiatry 62 ( Suppl 3 ) : 10–21 . Montejo AL , Majadas S , Rico-Villademoros F , et al. ( 2010 ) Frequency of sexual dysfunction in patients with a psychotic disorder receiving antipsychotics  . Journal of Sexual Medicine 7 : 3404–3413 . Mulhall J , King R , Glina S , et al. ( 2008 ) Importance of and satisfaction with sex among men and women worldwide : Results of the global better sex survey . Journal of Sexual Medicine 5 : 788–795 . Olfson M , Marcus SC , Tedeschi M , et al. ( 2006 ) Continuity of antidepressant treatment for adults with depression in the United States . American Journal of Psychiatry 163 : 101–108 To examine the conformance of current patterns of usual care for persons with schizophrenia to the Schizophrenia Patient Outcomes Research Team ( PORT ) Treatment Recommendations , the PORT surveyed a stratified r and om sample of 719 persons diagnosed with schizophrenia in two States . The types of treatment setting s surveyed included acute inpatient programs and continuing outpatient programs in urban and rural locales . Using data from medical record review s and patient interviews , the PORT assessed the conformance of current care with 12 of the Treatment Recommendations . The rates at which patients ' treatment conformed to the recommendations were modest at best , generally below 50 percent . Conformance rates were higher for pharmacological than for psychosocial treatments and in rural areas than in urban ones . Rates of Treatment Recommendation conformance for minority patients were lower than those for Caucasians , and patterns of care varied between the two States . The findings indicate that current usual treatment practice s likely fall substantially short of what would be recommended based on the best evidence on treatment efficacy . This disparity underscores the need for greater efforts to ensure that treatment research results are translated into practice
BACKGROUND Internet and mobile-based interventions provide a unique opportunity to deliver cost-effective , accessible , time-unlimited support to people with psychosis .
The aims of this study were to systematic ally compile and analyze the evidence on the acceptability , feasibility , safety and benefits of online and mobile-based interventions for psychosis .