A controlled trial of clothiapine and chlorpromazine in acute schizophrenic syndromes. [Comparative study of clothiapine and trifluoperazine in acute episodes of paranoid schizophrenia].
nan nan
We found no evidence to support the use of clotiapine in preference to other 'standard' or 'non-standard' treatments for management of people with acute psychotic illness. All trials in this review have important methodological problems. We do not wish to discourage clinicians from using clotiapine in the psychiatric emergency, but well-designed, conducted and reported trials are needed to properly determine the efficacy of this drug.
[Note: the three citations in the awaiting classification section of the review may alter the conclusions of the review once assessed.]