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Cheap Flights to Deuil-la-Barre, France - from US$109 RT - TripAdvisor\nCheap Flights to Deuil-la-Barre - Deuil-la-Barre, France Flights\nFind the best flight to Deuil-la-Barre\nGreat deals to Deuil-la-Barre\nMon, 03/11 - Sat, 03/16\nWed, 04/17 - Thu, 05/02\nThu, 02/28 - Tue, 03/05\nTue, 03/05 - Sun, 03/10\nSat, 10/26 - Sun, 10/27\n24 754 reviews\n41 154 reviews\n"Our recent easyJet flight from Amsterdam to Fuerteventura (return trip) was a very pleasant experience. First we were able to secure tickets for a very competitve price so we decided to treat ourselves to extra..."\nFlight stats for Deuil-la-Barre - did you know?\nDeuil-la-Barre is 27 km from Orly Field (Paris, France).\nDeuil-la-Barre is 16 km from Charles De Gaulle Airport (Paris, France).\nDeuil-la-Barre is 55 km from Beauvais-Tille Airport (Paris, France).


All entries for the birth/maiden name MEYER held within the Gravestone Photographic Resource\nwhere am I: Home > SEARCH >maiden name search > maiden name MEYER\nAll entries for the maiden name MEYER\nAgnes Kovermann nee Meyer 1804 1874\nrelationship not given of Ludivig Schirmeister Alten Friedhof Botanical Gardens Minden\nAlice Levy nee Meyer\n1910 36 relationship not given of Hector Levy Pere Lachaise (Pt1) Paris\nAnna Cahen nee Meyer\n1901 69 relationship not given of St�phanie Meyer Pere Lachaise (Pt1) Paris\nAnna Guivante nee Meyer 1874 1959 85 relationship not given of F�lix Jaskiewiez Pantin (section 8) Pantin\nAnna nee Meyer 1858 1906\nrelationship not given of Georg Alten Friedhof Botanical Gardens Minden\nAnna Liepmann nee Meyer 1841 1900 59 relationship not known of Julius Liepmann Alter St Matthaus Schoneberg\nAntoinette Bessy nee Meyer\n1915 60 wife of Petrus Bessy Cret de Roc St Etienne\nBertha Meyer nee Meyer 1822 1895 73 wife of Jaccn? Meyer Senerfelderplatz Berlin\nBertha Meyer nee Meyer 1822 1895\nwife of Jaccn Meyer Senerfelderplatz Jewish Berlin\nBerthe Michel nee Meyer\n1918 53 relationship not given of Hector Levy Pere Lachaise (Pt1) Paris\nBerthe Jaskiewiez nee Meyer 1868 1919 51 wife of F�lix Jaskiewiez Pantin (section 8) Pantin\nClara Pincus nee Meyer 1861 1912 41 first name on the monument Weissensee (pt 1) Berlin\nCl�mence Blum nee Meyer 1863 1951 88 relationship not given of Ad�le Meyer Montparnasse Paris\nCl�mence Blum nee Meyer 1863 1951 88 relationship not given of Blanche Marie Madeleine Froidefond Montparnasse Paris\nCl�mence Blum nee Meyer 1863 1951 88 relationship not given of Ad�le Meyer Montparnasse Pt3 Paris\nDenise Millet nee Meyer 1923 1945 22 relationship not given of Ad�le Meyer Montparnasse Pt3 Paris\nDenise Millet nee Meyer 1923 1945 22 relationship not given of Blanche Marie Madeleine Froidefond Montparnasse Paris\nDenise Millet nee Meyer 1923 1945 22 relationship not given of Ad�le Meyer Montparnasse Paris\nEmma Esther Cohn nee Meyer\n1902 68 relationship not given of Salomon Hirsch Cohn Jewish Pt2 Senerfelderplatz\nFeodore Heidenreich nee Meyer\n1885 47 first name on the monument Jewish Pt2 Senerfelderplatz\nHenriette Mendelsohn nee Meyer\n1862 84 relationship not given of Joseph Mendelsohn Jewish Pt2 Senerfelderplatz\nJeanne Burckel nee Meyer 1895 1964 69 relationship not given of Marie Burckel Pt2 Bagneux\nJohanna Lazarus nee Meyer\n1871 31 first name on the monument Jewish Pt2 Senerfelderplatz\nJulie Bernstein nee Meyer 1871 1962 91 relationship not given of F�lix Jaskiewiez Pantin (section 8) Pantin\nMadeleine Behr nee Meyer 1822 1907 85 first name on the monument Montparnasse Paris\nMadeleine Schill nee Meyer 1838 1901 63 relationship not given of Anne Schill Pantin (section 14) Pantin\nMadeleine Behr nee Meyer 1822 1907 85 first name on the monument Montparnasse Pt3 Paris\nMadeleine Jacob nee Meyer 1874 1956 82 relationship not given of Jacques Meyer Pantin (section 8) Pantin\nMargaret Mary Hall nee Meyer mother of Janet Elizabeth Hall Lawn (part 2) Cohuna\nMarie Levine nee Meyer 1888 1961 73 relationship not given of Ren�e Levine Pt2 Bagneux\nMarie Merle Bernheim nee Meyer 1857 1936 79 relationship not given of Julien Bernheim Montparnasse Pt2 Paris\nMathilde L�vy nee Meyer 1872 1941 69 wife of Blanche Marie Madeleine Froidefond Montparnasse Paris\nMathilde L�vy nee Meyer 1872 1941 69 wife of Lazare L�vy Montparnasse Paris\nMathilde L�vy nee Meyer 1872 1941 69 wife of Lazare L�vy Montparnasse Pt3 Paris\nPaule Loiseau nee Meyer 1906 1983 77 relationship not given of Blanche Marie Madeleine Froidefond Montparnasse Paris\nPaule Loiseau nee Meyer 1906 1983 77 relationship not given of Sara Meyer Montparnasse Paris\nPaule Loiseau nee Meyer 1906 1983 77 relationship not given of Sara Meyer Montparnasse Pt3 Paris\nR Sabine Contenius nee Meyer 1834 1906 72 relationship not given of Eduard Rudolph Contenius Friedhofe Vor Dem Halleschen Tor Berlin\nRachel Crombac nee Meyer 1832 1909 77 relationship not given of Salomon Deutsch Pantin (section 8) Pantin\nReine Bloch nee Meyer 1881 1909 28 relationship not given of Blanche Marie Madeleine Froidefond Montparnasse Paris\nReine Weill nee Meyer 1878 1945 67 relationship not given of Blanche Marie Madeleine Froidefond Montparnasse Paris\nReine Bloch nee Meyer 1881 1909 28 relationship not given of Madeleine Behr Montparnasse Paris\nReine Bloch nee Meyer 1881 1909 28 relationship not given of Madeleine Behr Montparnasse Pt3 Paris\nReine Weill nee Meyer 1878 1945 67 relationship not given of Sara Meyer Montparnasse Paris\nReine Weill nee Meyer 1878 1945 67 relationship not given of Sara Meyer Montparnasse Pt3 Paris\nRosalie Bonheur nee Meyer 1872 1912 40 relationship not given of Blanche Marie Madeleine Froidefond Montparnasse Paris\nRosalie Bonheur nee Meyer 1872 1912 40 relationship not given of Madeleine Behr Montparnasse Pt3 Paris\nRosalie Bonheur nee Meyer 1872 1912 40 relationship not given of Madeleine Behr Montparnasse Paris\nSaret Levy nee Meyer 1854 1912 58 relationship not given of Jacques Meyer Pantin (section 8) Pantin\nSophie Wyler nee Meyer 1860 1919 59 relationship not given of Blanche Marie Madeleine Froidefond Montparnasse Paris\nSophie Wyler nee Meyer 1860 1919 59 relationship not given of Ad�le Meyer Montparnasse Paris\nSophie Wyler nee Meyer 1860 1919 59 relationship not given of Ad�le Meyer Montparnasse Pt3 Paris\nValetine Dreyfus nee Meyer\n1943 63 relationship not given of Clara Schornstein Pere Lachaise (Pt2) Paris\nVeilchen Fournier nee Meyer 1834 1889 55 first name on the monument Alter Luisenstadt (part 1) Schoneberg\nWilhemine Neumann nee Meyer 1810 1887 77 relationship not given of Ferdinand Neumann Friedhofe Vor Dem Halleschen Tor Berlin\nThis page contains a list of all the entries for the maiden name MEYER that are held within the Gravestone Photographic Resource online database. It is quite likely that there are also entries available for alternative spellings of this name. It is very easy for you to check to see if there are any alternative spellings: you just need to look at the page that shows all the names listed under the starting letter (M in this case) of the maiden name you are interested in.\nAll comment / feedback / help requests within the Gravestone Photographic Resource for the name MEYER


MEDIA AG INNOV.MED. DE0006633308 Cours Action MJA, Cotation Bourse Hannover - Boursorama\nCours MEDIA AG INNOV.MED. DE0006633308\nMEDIA AG INNOV.MED. DE0006633308\n23.03.18 / 13:53:22\nAjouter MEDIA AG INNOV.MED. DE0006633308 à un portefeuille virtuel\nAjouter MEDIA AG INNOV.MED. DE0006633308 à mes listes\nDernières informations à propos de MEDIA AG INNOV.MED. DE0006633308\nDerniers messages sur le forum MEDIA AG INNOV.MED. DE0006633308


-genre_facet:"periodicals" -genre_facet:"History" -topic_facet:"Race in literature" -topic_facet:"Social ethics" -author_facet:"Santos, Michael, 1964-" -author_facet:"Davis, Angela Y. 1944-" topic_facet:"SOCIAL SCIENCE" era_facet:"1800-1899" language:"English"\nClear Filter NOT Genre: periodicals Clear Filter NOT Genre: History Clear Filter NOT Subject: Race in literature Clear Filter NOT Subject: Social ethics Clear Filter Subject: SOCIAL SCIENCE Clear Filter NOT Author: Santos, Michael, 1964- Clear Filter NOT Author: Davis, Angela Y. 1944- Clear Filter Era: 1800-1899 Clear Filter Language: English


Steensma sneon te hôf brocht | Omrop Fryslân Skip to main content\nSteensma sneon te hôf brocht 14 maaie 2004 - 00:00\nDe begraffenis fan de yn Irak omkommen Dave Steensma sil sneon yn besletten kring plakfine. Steensma wurdt mei militêre eare begroeven. Minister Kamp fan Definsje is op fersyk fan de famylje by de begraffenis oanwêzich.\nDe kiste wurdt droegen troch seis direkte kollega's. Ek de man dy't by de oanslach ferwûne rekke is by de útfeart oanwêzich. Op fersyk fan de famylje sil de kommandant fan de lânmacht net by de begraffenis wêze.


FDA goedkard Regorafenib behannelje kolorektale kanker, GIST, HCC\n/blog/Gallery/FDA goedkard Regorafenib behannelje kolorektale kanker, GIST, HCC\nPosted op 03 / 30 / 2021 by 阿斯劳 skreau yn Gallery.\nWat is Regorafenib?\nWêrom is Regorafenib goedkard troch FDA?\nHoe wurket Regorafenib?\nWat wurdt Regorafenib Main brûkt foar?\nHokker foardielen fan Regorafenib binne toand yn stúdzjes?\nHokker risiko's / side-effekten kin Regorafenib bringe?\nHoe kin ik Regorafenib opslaan en / of goaie?\nTakomstige oanwizings fan Regorafenib\nRegorafenib (CAS: 755037-03-7), ferkocht ûnder oaren ûnder de merknamme Stivarga, is in mûnling multi-kinase-ynhibitor ûntwikkele troch Bayer dy't rjochte is op angiogene, stromale en onkogene reseptor tyrosine kinase (RTK). Regorafenib toant anty-angiogene aktiviteit fanwege syn dûbele doelbewuste VEGFR2-TIE2 tyrosinekinase-ynhibysje. Sûnt 2009 waard it bestudearre as in potensjele behannelingopsje yn meardere tumortypes. Tsjin 2015 hie it twa Amerikaanske goedkeuringen foar avansearre kankers.\nWêrom is Regorafenib Besocht troch FDA?\nDe Jeropeesk medisynagintskip besletten dat de foardielen fan Regorafenib grutter binne dan har risiko's en advisearre dat it goedkard wurdt foar gebrûk yn 'e EU. It Komitee stelde fêst dat yn kolorektale kanker de foardielen yn termen fan it útwreidzjen fan pasjintoerlibjen beskieden wiene, mar beskôgen dat se de risiko's weagje by pasjinten foar wa't d'r gjin oare oerbleaune behannele opsjes binne. Sjoen de side-effekten beskôge de CHMP it lykwols wichtich om manieren te finen om subgroepen fan pasjinten te identifisearjen dy't faker reagearje op Stivarga.\nWat GIST en HCC oanbelanget, stelde it Komitee fêst dat de foarútsichten min binne foar pasjinten waans sykte nettsjinsteande eardere behanneling slimmer wurdt. Fan Stivarga waard oantoand dat de ferswakking fan 'e sykte by dizze pasjinten fertrage. Foar pasjinten mei HCC late dit ta in ferbettering fan 'e tiid fan pasjinten libbe. De side-effekten fan Stivarga binne beheare.\nHoe docht Regorafenib Wurk?\nRegorafenib is in lytse molekule-ynhibitor fan meardere membraanbûnen en yntrasellulêre kinasen belutsen by normale sellulêre funksjes en yn pathologyske prosessen lykas onkogenese, tumor angiogenese, en ûnderhâld fan 'e tumormikromiljo. Yn in vitro biogemyske as sellulêre assays remme regorafenib as de wichtichste minsklike aktive metaboliten M-2 en M-5 de aktiviteit fan RET, VEGFR1, VEGFR2, VEGFR3, KIT, PDGFR-alpha, PDGFR-beta, FGFR1, FGFR2, TIE2, DDR2, TrkA, Eph2A, RAF-1, BRAF, BRAFV600E, SAPK2, PTK5, en Abl by konsintraasjes regorafenib dy't klinysk binne berikt. Yn in vivo-modellen demonstrearre regorafenib anty-angiogene aktiviteit yn in rattumormodel, en remming fan tumorgroei, lykas anty-metastatyske aktiviteit yn ferskate mûs-xenograftmodellen, wêrûnder guon foar minsklik kolorektaal carcinoma.\nAASraw is de profesjonele fabrikant fan Regorafenib.\nWat is Regorafenib Main brûkt foar?\nRegorafenib is in medisyn foar kanker dat de aktive stof befettet regorafenib puol, It wurdt allinich brûkt om de folgjende kankers te behanneljen:\n① Kolorektale kanker (kanker fan 'e darm en rectum) dy't ferspraat is nei oare dielen fan it lichem;\nRo Gastrointestinale stromale tumor (GIST, in kanker fan 'e mage en darm) dy't ferspraat is of chirurgysk net kin wurde fuorthelle;\n③ Hepatocellular carcinoma (HCC, in kanker fan 'e lever).\nRegorafenib wurdt brûkt yn pasjinten dy't al behannele binne mei, of dy't net kinne wurde jûn, oare beskikbere behannelingen. Foar kolorektale kanker omfetsje dizze gemoterapy basearre op medisinen neamd fluorpyrimidines en behanneling mei oare kanker medisinen bekend as anty-VEGF- en anty-EGFR-terapyen. Pasjinten mei GIST moatte behanneling hawwe besocht mei imatinib en sunitinib en pasjinten mei HCC moatte sorafenib hawwe besocht foardat se begjinne mei behanneling mei Regorafenib.\nWat foardielen fan Regorafenib binne toand yn Stúdzjes?\n❶ Colorectale kanker\nYn in haadstúdzje mei 760 pasjinten mei metastatyske kolorektale kanker dy't nei standertterapy foarútgong wie, waard Regorafenib fergelike mei placebo (in dummy-behanneling) en de wichtichste mjitte fan effektiviteit wie algemiene oerlibjen (de tiid tiid dat pasjinten libbe). Alle pasjinten krigen ek stypjende soarch, ynklusyf pine medisinen en behanneling foar ynfeksjes. De stúdzje toande dat Regorafenib it oerlibjen ferbettere, mei behannele pasjinten dy't gemiddeld 6.4 moannen wennen, yn ferliking mei 5 moannen foar de placebo.\n❷ GIST(Avansearre gastrointestinale stromale tumors)\nYn in oare haadstúdzje waard Regorafenib fergelike mei placebo yn 199 pasjinten mei GIST dy't ferspraat wiene of ynoperabel wiene en dy't ek de bêste stypjende soarch krigen. Stypjende soarch omfette behannelingen lykas pineferliening, antibiotika, en bloedtransfúzjes dy't de pasjint helpe, mar sûnder de behanneling fan 'e kanker, De stúdzje toande dat Regorafenib mei stypjende soarch effektyf wie by it ferlingjen fan 'e tiid fan pasjinten libbe sûnder dat har sykte minder waard. Pasjinten behannele mei Regorafenib wennen gemiddeld 4.8 moannen sûnder dat har sykte slimmer waard yn ferliking mei 0.9 moannen foar pasjinten dy't placebo en stypjende soarch nimme.\n❸ HCC(Avansearre hepatocellulêr kanker)\nYn in haadstúdzje mei 573 pasjinten mei HCC dy't slimmer wiene nei behanneling mei sorafenib, Regorafenib waard fergelike mei placebo en de wichtichste mjitte fan effektiviteit wie algemiene oerlibjen. Alle pasjinten krigen ek stypjende soarch. De stúdzje toande oan dat Stivarga de tiid fergrutte dat pasjinten algemien wennen, mei pasjinten behannele mei Regorafenib dy't gemiddeld 10.6 moannen wennen, yn ferliking mei 7.8 moannen foar de placebo.\nWat risiko's / side-effekten docht Regorafenib Mei bringe?\nInfeksje. Regorafenib kin liede ta in heger risiko op ynfeksjes, fral fan 'e urinekanaal, noas, kiel en long. Regorafenib kin liede ta in heger risiko op skimmelynfeksjes fan de slijmvliezen, hûd as it lichem. Fertel jo sûnenssoarch fuortendaliks as jo koarts krije, hurde hoest mei of sûnder in ferheging fan produksje fan slym (sputum), earnstige seare keel, koart sykheljen, ferbaarnen as pine by urinearjen, ûngewoane fagina-ûntlizzing of irritaasje, roodheid, swelling of pine yn elk diel fan it lichem\nSevere bliedend. Regorafenib kin bloeden feroarsaakje, wat serieus kin wêze en soms ta de dea liede kin. Fertel jo soarchferliener as jo tekens hawwe fan bloedearjen by it nimmen fan Regorafenib, ynklusief: bloed spuie of as jo spuie op kofjegrûn liket, rôze of brune urine, read of swart (liket op teer) stuollen, hoastjen fan bloed of bloedklont, menstruaasjebloed dat swierder is dan normaal, ûngewoane fagina-bloeding, noasbloedingen dy't faak barre, blauwe plakken en lichte kop.\nA tear yn jo mage of darmwand (perforaasje fan 'e darm). Regorafenib kin in trien yn jo mage of darmwand feroarsaakje dy't serieus kin wêze en soms ta de dea liede kin. Nim direkt kontakt op mei jo soarchferliener as jo earnstige pine of swelling opmerke yn jo mage gebiet (búk), koarts, kjeld, mislikens, spuie of útdroeging.\nA hûdprobleem neamd hûd-foet hûdreaksje en slimme hûdútslach. Hânreaksjes fan 'e hân-foet binne faak en kinne soms earnstich wêze. Fertel jo soarchfersekerder daliks as jo readheid, pine, blierren, bloed, of swelling krije op 'e palmen fan jo hannen en soallen fan jo fuotten, of in heule útslach.\nHigh bloeddruk. Jo bloeddruk moat elke wike wurde kontroleare foar de earste 6 wiken fan start fan Regorafenib. Jo bloeddruk moat regelmjittich wurde kontroleare en elke hege bloeddruk moat wurde behannele wylst jo Regorafenib krije. Fertel jo soarchoanbieder as jo swiere hoofdpijn, lichte koppen, of feroaringen yn jo fisy hawwe.\nDferhege bloedstream nei it hert en hertoanfal. Krij needhelp as jo pine op 'e boarst hawwe, sykheljen hawwe, duizelich fiele, of fiele wolle om út te fallen.\nA tastân neamd reversibel posterior leukoencefalopatysyndroam (RPLS). Belje jo medyske leveransier direkt as jo earnstige hoofdpijn, oanfal, ferwarring, feroaring yn fyzje, as problemen tinke\nRisk fan wûnhelingsproblemen. Wûnen kinne miskien net goed genêze by behanneling fan Regorafenib. Fertel jo soarchferliener as jo fan plan binne sjirurgy te hawwen foardat jo begjinne of ûnder behanneling mei Regorafenib.\n▪ Jo moatte ophâlde mei it nimmen fan Regorafenib op syn minst 2 wiken foar plande operaasje.\n▪ Jo leveransier fan jo sûnenssoarch moat jo fertelle wannear't jo opnij begjinne mei Regorafenib te nimmen nei in operaasje.\nDe meast foarkommende side-effekten mei Regorafenib omfetsje pine ynklusyf mage-gebiet (abdomen); wurgens, swakte, wurgens; diarree (faak of losse stoelbewegingen); fermindere appetit; ynfeksje; stimferoaring as heisens; tanimming fan bepaalde leverfunksjetests; koarts; swelling, pine, en readheid fan 'e bek yn' e mûle, kiel, mage en darm (mucositis); en gewichtsverlies.\n♦ Bewarje tablets yn 'e orizjinele kontener by keamertemperatuer. Hâld de pet goed ticht. Nim de kubus of it pakket antimistoarium net út.\n♦ Smyt elk diel dat net brûkt wurdt 7 wiken nei it iepenjen fan de flesse.\n♦ Bewarje op in droech plak. Bewarje net yn in badkeamer.\n♦ Hâld alle medisinen op in feilich plak. Hâld alle medisinen bûten it berik fan bern en húsdieren.\n♦ Smyt ûngebrûkte of ferrûne medisinen fuort. Spoel gjin húske of spielje in ôffal, útsein as jo wurdt ferteld dat te dwaan. Kontrolearje mei jo apteker as jo fragen hawwe oer de bêste manier om drugs út te goaien. D'r kinne programma's foar weromname fan drugs wêze yn jo gebiet.\nFiif jier nei syn goedkarring bliuwt regorafenib in medisyn mei beheinde klinyske behanneling. Goedkard gebrûk yn kolorektale kanker, GIST en HCC is allinich foar avansearre metastatyske sykte. Yn kombinaasje mei hege kosten is d'r op it stuit lyts klinysk foardiel foar pasjinten. Boppedat wurde ûnderskate proeven útfierd om it te definiearjen as in nije behannelingopsje. Takomstige oanwizings foar dit medisyn omfetsje it behear fan osteosarkoom. In resinte placebo-kontroleare, dûbelblinde proef yn Frankryk hat in ferheging fan progressyfrije oerlibjen sjen litten troch in faktor fan 3 yn pasjinten mei metastatyske osteosarkoom dy't elke line fan behanneling hawwe mislearre. Oertsjûgjend litte dizze nije gegevens foardiel sjen op avansearre metastatyske sykte as lêste rêdmiddel, lykas alle hjoeddeistige goedkarde gebrûk.\nResinte gegevens suggerearje in mooglik synergysk effekt tusken regorafenib en immuunkontrolepunt-ynhibitoren, lykas is oanjûn yn 'e REGONIVO-proef. (38% yn maagkanker en 44% yn kolorektale kanker) en in tolerabel profyl foar side-effekten yn 'e kombinaasjegroep. Dit yntrigearjende foardiel kin wêze troch reduksje fan tumor-assosjeare makrofagen troch regorafenib, wêrtroch de gefoelens fan 'e tumor foar nivolumab fergruttet. Op it stuit is de REGONIVO-faze II-proef ûnderweis en koe dizze hypoteze al gau befestigje. Derneist hat in lêste faze II klinyske proef oantoand dat regorafenib superieur is oan lomustine yn avansearre en werhelle glioblastoma. De REGOMA-proef, yn Itaalje, hat in signifikante ferbettering oanjûn yn algemiene oerlibjen (gefaarferhâlding 36; 0.50% fertrouwen ynterval 95-0.33; log-rank p = 0.75) yn fergeliking mei lomustine-terapy.\nDe REVERSE stúdzjes binne útfierd mei regorafenib en cetuximab by de behanneling fan metastatyske kolorektale kanker. De resultaten krigen oer de folchoarder fan it gebrûk fan sokke medisinen by de behanneling fan dizze kanker suggerearje dat de ideale oarder de earste administraasje fan regorafenib wêze soe, folge troch cetuximab, oars as it hjoeddeistige standertprotokol. De resultaten lieten ferbettere algemiene oerlibjen fan 'e pasjinten sjen en it foardiel like meast te wurde dreaun troch gruttere aktiviteit fan cetuximab dan regorafenib as de twadde behanneling.\nDe YNTEGRAAT proef fan regorafenib monoterapy by maagkanker toande dat dit medisyn goed tolerearre waard en dat d'r gjin skea wie yn 'e libbenskwaliteit fan pasjinten yn ferliking mei dyjingen dy't placebo krigen en dat it net in oermjittich negatyf effekt like te hawwen op dy parameters fan toksisiteit. Undersyksprojekten markeare dat baseline-nivo's fan pine, appetit, constipaasje en fysyk funksjonearjen waarden fûn as signifikante prognostyske faktoaren foar oerlibjen. Ek die dizze proef oantoand dat regorafenib in protte aktiviteit hie yn it primêre progressyfrije survival eindpunt. Boppedat, de faze II REDOS-proef waard útfierd fan 2015–2018 en auteurs lieten sjen dat in dose-eskalaasjestrategy foar regorafenib in berikber alternatyf is foar de standert regorafenib-dosearingsstrategy fan 160 mg / dei, fral yn pasjinten mei metastatyske kolorektale kanker. It waard ek fûn dat pasjinten behannele mei dose-eskalaasje in hegere frekwinsje hienen fan behanneling nei foarútgong en numeryk langer algemien oerlibjen.\nOangeande ferdraachsumens fan regorafenib as brûkt foar behanneljen fan kolorektale kanker, binne beheinde gegevens beskikber oer de tolerânsje yn 'e âldere pasjintepopulaasje, en it beslút moat wurde nommen mei it each op it minimale oerlibbensfoardiel en it toxicityprofyl. Sjoen dit medisyn yn HCC-behanneling beklamje ûndersyksprojekten dat d'r in akseptabel tolerânsjeprofyl is en dat regorafenib in oerlibbensfoardiel leveret. GIST behanneling, Ferskate auteurs stelle dat regorafenib goed tolerearre wurdt sûnder unferwachte toksisiteiten.\nFierder ûndersyk is nedich om te bepalen hokker pasjinten it measte profitearje kinne fan dit medisyn. Fanôf 2019 wurde trochgeande proeven testen oft regorafenib de resultaten kin ferbetterje yn sêfte weefsel sarkomen, lykas osteogene sarkoom, liposarkoom, Ewing sarkoom en rhabdomyosarkoom.\nNettsjinsteande 5 jier fan goedkarring en promovende farmakodynamika hat regorafenib in beheind, doch statistysk signifikant foardiel sjen litten foar ferskate soarten fêste tumors. Markearre oanwizings omfetsje kolorektale kanker, GIST en HCC. Avansearre faze II-proeven hawwe signifikante ferbetteringen sjen litten yn it oerlibjen foar maagkanker, glioblastoma en osteosarkoom, wat kin oanjaan op takomstige opname yn markearre oanwizings.\nKombinaasje-terapy mei ymmúnkontrolepunt-ynhibitoren is oantoand as foardielich yn faze I-proeven, en faze II-proeven wurde útfierd. Op it stuit wurdt regorafenib ek ûndersocht foar oare kankers. In protte yndividuele side-effekten kinne brûkt wurde as markers foar bettere resultaten mei behanneling. Under dy binne hand-foetsyndroam en hypothyroïdisme it meast relatearre oan ferbettere oerlibjen. Gearfetsjend hawwe ûndersiken oantoand dat regorafenib it oerlibjen signifikant kin ferbetterje mei in akseptabele tolerânsje yn in ferskaat oan fêste tumors.\n Krishnamoorthy SK, Relias V, Sebastian S, et al. Behear fan regorafenib-relatearre toksisiteiten: in resinsje. Ther Adv Gastroenterol. 2015; 8: 285–97.\n Thangaraju P, Singh H, Chakrabarti A. Regorafenib: in roman tyrosine kinase-ynhibitor: in koarte oersjoch fan har therapeutyske potensjeel yn 'e behanneling fan metastatysk kolorektaal kanker en avansearre gastrointestinale stromale tumors. Yndiaanske J Kanker. 2015; 52: 257-60.\n Grünewald FS, Prota AE, Giese A, Ballmer-Hofer K. Struktuerfunksje-analyse fan VEGF-receptoraktivaasje en de rol fan coreceptors yn angiogenyske sinjalearring. Biochim Biophys Acta Proteins Proteomics. 2010; 1804: 567–80.\n Shinkai A, Ito M, Anazawa H, et al. Mapping fan 'e siden dy't belutsen binne by ligandferiening en dissosiaasje op it ekstrasellulêre domein fan' e kinase ynfoegje domein-befetsje reptor foar fassile endotheliale groeifaktor. J Biol Chem. 1998; 273: 31283–8.\n Fuh G, Li B, Crowley C, et al. Easken foar bining en sinjalearjen fan 'e kinase-domeinreceptor foar fassile endotheliale groeifaktor. J Biol Chem. 1998; 273: 11197–204.\n Eriksson A, Cao R, Roy J, et al. Lyts GTP-binend aaiwyt Rac is in essensjele mediator fan fassilêre endotheliale groeifaktor-feroarsake endotheliale fenestraasjes en fassile permeabiliteit. Sirkulaasje. 2003; 107: 1532–8.\n Ascierto PA, Kirkwood JM, Grob JJ, et al. De rol fan BRAF V600 mutaasje yn melanoom. J Transl Med. 2012; 10: 85.\n Emuss V, Garnett M, Mason C, Marais R. Mutaasjes fan C-RAF binne seldsum yn minsklike kanker, om't C-RAF in lege basale kinaseaktiviteit hat yn ferliking mei B-RAF. Cancer Res. 2005; 65: 9719–26.\n Bruix J, Qin S, Merle P, et al. Regorafenib foar pasjinten mei hepatocellular carcinoma dy't progresseare op sorafenib-behanneling (RESORCE): in randomisearre, dûbelblinde, placebo-kontroleare, faze 3-proef. Lancet. 2017; 389: 56-66.\n Martin AJ, Gibbs E, Sjoquist K, et al. Sûnens relatearre libbenskwaliteit assosjeare mei behanneling fan regorafenib yn refraktêr avansearre maag-adenokarsinoom. Maagkanker. 2018; 21: 473-80.\n Heo YA, Syed YY. Regorafenib: in resinsje yn hepatocellular carcinoma. Drugs. 2018; 78: 951–8.\n Yin X, Yin Y, Shen C, Chen H, Wang J, Cai Z, et al. Ferkearde barrens risiko assosjeare mei regorafenib by de behanneling fan avansearre fêste tumors: meta-analyze fan randomisearre kontroleare proeven. Onco Doelt Ther. 2018; 11: 6405-14.\n Lombardi G, De Salvo GL, Brandes AA, et al. Regorafenib yn ferliking mei lomustine by pasjinten mei weromkeard glioblastoma (REGOMA): in multysintrum, iepen-label, randomisearre, kontroleare, faze 2-proef. Lancet Oncol. 2019; 20: 110–9.\n Bekaii-Saab T. In neier besjen fan regorafenib. Clin Adv Hematol Oncol. 2018; 16: 667-9.\n Yoshino K, Manaka D, Kudo R, et al. Metastatyske kolorektale kanker reageare op regorafenib foar 2 jier: in saakrapport. J Med Case Rep.2017; 11: 227.\nHoe kinne jo Trenbololone-resept brûke om Trenbolone Enanthate-poeder te mingjen\nWiidweidige ynlieding oer "Longkankermoordenaar" Gefitinib 6 fragen oer Afatinib op anty-kaners (NSCLC)


Station info for JANSVR3hA – Google Maps APRS\nAPRS object JANSVR3hA - show graphs\n32°57.60' N 91°20.40' W - locator EM42HX90EJ - show map - static map\n7.4 miles North bearing 22° from Oak Grove, West Carroll Parish, Louisiana, United States [?]\n11.3 miles Southwest bearing 204° from Eudora, Chicot County, Arkansas, United States\n54.9 miles Northeast bearing 55° from Monroe, Ouachita Parish, Louisiana, United States\n81.2 miles Northwest bearing 305° from Jackson, Hinds County, Mississippi, United States\n2018-04-14 00:34:55 EDT (191d 4h7m ago)\n2018-04-13 23:34:55 CDT local time at Oak Grove, United States [?]\nJANSVR00A JANSVR01A JANSVR02A JANSVR06A JANSVR07A JANSVR08A JANSVR09A JANSVR0aA JANSVR0BA JANSVR0DA JANSVR0eA JANSVR0HA JANSVR0IA JANSVR0jA JANSVR0kA JANSVR0lA JANSVR0nA JANSVR0oA JANSVR0pA JANSVR0RA JANSVR0sA JANSVR0tA JANSVR0vA JANSVR0WA JANSVR0XA JANSVR10A JANSVR12A JANSVR14A JANSVR17A JANSVR1BA JANSVR1JA JANSVR1QA JANSVR1RA JANSVR1tA JANSVR1VA JANSVR1ZA JANSVR22A JANSVR28A JANSVR2BA JANSVR2eA JANSVR2FA JANSVR2gA JANSVR2KA JANSVR2LA JANSVR2mA JANSVR2VA JANSVR2wA JANSVR2xA JANSVR3kA JANSVR3lA JANSVR3pA JANSVR3RA JANSVR3TA JANSVR45A JANSVR4aA JANSVR4dA JANSVR4GA JANSVR4GB JANSVR4HA JANSVR4iA JANSVR4kA JANSVR4mA JANSVR4nA JANSVR4OA JANSVR4PA JANSVR4QA JANSVR4TA JANSVR4vA JANSVR4wA JANSVR4ZA JANSVR56A JANSVR5bA JANSVR5CA JANSVR5GA JANSVR5QA JANSVR5RA JANSVR62A JANSVR63A JANSVR6BA JANSVR6DA JANSVR6OA JANSVR6pA JANSVR6RA JANSVR71A JANSVR76A JANSVR7nA JANSVR7PA JANSVR7RA JANSVR7WA JANSVR7YA JANSVR88A JANSVR8pA JANSVR91A JANSVR96A JANSVR97A JANSVR9bA JANSVR9dA JANSVR9uA JANSVRACA JANSVRADA JANSVRAeA JANSVRAhA JANSVRANA JANSVRBiA JANSVRBLA JANSVRBrA JANSVRC0A JANSVRCGA JANSVRCnA JANSVRCqA JANSVRCRA JANSVRD5A JANSVRDOA JANSVRDSA JANSVRE5A JANSVRE7A JANSVREbA JANSVREgA JANSVREpA JANSVREqA JANSVREsA JANSVRF3A JANSVRFBA JANSVRFeA JANSVRFIA JANSVRFnA JANSVRFPA JANSVRFTA JANSVRFuA JANSVRFVA JANSVRG7A JANSVRGCA JANSVRGMA JANSVRGOA JANSVRGpA JANSVRHpA JANSVRHsA JANSVRHZA JANSVRI1A JANSVRI2A JANSVRI6A JANSVRIAA JANSVRIeA JANSVRIfA JANSVRIJA JANSVRImA JANSVRINA JANSVRISA JANSVRIVA JANSVRIYA JANSVRJaA JANSVRJDA JANSVRJIA JANSVRJJA JANSVRJLA JANSVRJnA JANSVRJPA JANSVRJrA JANSVRJSA JANSVRJTA JANSVRJvA JANSVRJXA JANSVRJZA JANSVRK1A JANSVRK3A JANSVRK6A JANSVRKaA JANSVRKBA JANSVRKGA JANSVRKhA JANSVRKIA JANSVRKJA JANSVRKLA JANSVRKNA JANSVRKoA JANSVRKQA JANSVRKRA JANSVRKsA JANSVRKtA JANSVRKuA JANSVRKVA JANSVRKwA JANSVRKYA JANSVRL0A JANSVRL3A JANSVRL5A JANSVRL8A JANSVRL9A JANSVRLaA JANSVRLbA JANSVRLcA JANSVRLDA JANSVRLFA JANSVRLhA JANSVRLIA JANSVRLjA JANSVRLKA JANSVRLmA JANSVRLNA JANSVRLoA JANSVRLpA JANSVRLpB JANSVRLqA JANSVRLrA JANSVRLSA JANSVRLtA JANSVRLuA JANSVRLVA JANSVRLwA JANSVRLxA JANSVRM2A JANSVRM5A JANSVRM7A JANSVRMbA JANSVRMcA JANSVRMdA JANSVRMFA JANSVRMgA JANSVRMHA JANSVRMiA JANSVRMjA JANSVRMKA JANSVRMLA JANSVRMmA JANSVRMoA JANSVRMPA JANSVRMRA JANSVRMsA JANSVRMuA JANSVRMVA JANSVRMWA JANSVRMxA JANSVRN2A JANSVRN4A JANSVRN5A JANSVRN6A JANSVRN7A JANSVRN8A JANSVRNaA JANSVRNBA JANSVRNCA JANSVRNdA JANSVRNeA JANSVRNgA JANSVRNHA JANSVRNIA JANSVRNJA JANSVRNLA JANSVRNMA JANSVRNNA JANSVRNoA JANSVRNoB JANSVRNpA JANSVRNrA JANSVRNsA JANSVRNuA JANSVRNVA JANSVRNwA JANSVRNXA JANSVRNYA JANSVRNZA\nStations near current position of JANSVR3hA - show more


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Avenue du Castel 10, Woluwe-Saint-Lambert - Estimate and neighbourhood info on Realo\nAvenue du Castel 10, 1200 Woluwe-Saint-Lambert\nCoordinates 50°50'31.4"N 4°24' 49.4"E\nGet an accurate market valuation and full report for the property at Avenue du Castel 10, Avenue De Broqueville-Nord, Woluwe-Saint-Lambert (1200).\n12 - 17/6\n1/8 - 11/11\nGet the Realo Estimate Report to reveal the price history of Avenue du Castel 10, 1200 Woluwe-Saint-Lambert\nSupermarkets (including White Night, Carrefour market, Proxy Delhaize, Picard, Aldi, Carrefour express, Färm, Smatch, Shop & Go Delhaize)\nBakeries (including Le Pain Quotidien, De Baere, Au Croquant, Le Saint Michel, La Cantina, Le pain d'en face, Paul Montgomery, La Balade De Milla, Puk's Cafe, Le Cep)\nButchers (including Maison Lanssens, Boucherie / Slagerij Tomberg)\nRestaurants (including Le Schievelavabo, Le Coach, Jardin de Nicolas, The Open, Chez Fernand, Le Fair-Play, Yama Sushi, Le Martin Pêcheur, Le Coq en Pâte, Le Monde Est Petit)\nBars (including La Cuve à Bière, Léopold Café Presse, Le Petit Paris, Starbucks, Le Batonnier, Clover Bar, Le Lion Belge, No Name's Café, L'Aristo, Le Diplo )\nPharmacies (including Pharmacie Du Tomberg, Pharmacie Druais, Pharmacie Debrus Apotheek )\nDoctors (including Hana Abboud, Philippe Accarain, Agnes Angheben, Gerard Arnould, Philippe Aussems, Yves Balon-Perin, Francoise Belche, Jean-Pierre Belpalme, Pierre Berger, Philippe Bertholet)\nHospital (including Europaziekenhuizen – Cliniques De L’Europe)\nBanks (including ING, BNP Paribas Fortis, Belfius, Deutsche Bank, CBC )\nHow expensive is a house in Avenue De Broqueville-Nord?\nAverage price: € 2.139,42/m2\nEvolution of the average price for a house in Avenue De Broqueville-Nord over the last 43 years.\nfrom which 25 in Woluwe-Saint-Lambert\nfrom which 10 in Woluwe-Saint-Lambert\nfrom which 24 in Woluwe-Saint-Lambert\nfrom which 4 in Woluwe-Saint-Lambert\nThe Realo Estimate is the estimate of the market price of a property. A sale/rent estimate for Avenue du Castel 10, 1200 Woluwe-Saint-Lambert is available now.


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eigenstates: Definition, Word Game Analysis\neigenstates Best Plays\nWords In eigenstates\neigenstates in Scrabble®\nThe word eigenstates is playable in Scrabble®, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.\nHighest Scoring Scrabble® Plays In The Letters eigenstates :\neasiest, estates, geneses, genesis, gestate, ingests, instate, neatest, negates, sagiest, sateens, seating, seitans, seitens, senates, sensate, sestina, sestine, settees, setting, signees, signets, stating, statins, tasting, teasing, teenage, tensest, tentage, testing\nAll Scrabble® Plays For The Word eigenstates\nThe 200 Highest Scoring Scrabble® Plays For Words Using The Letters In eigenstates\neigenstates in Words With Friends™\nThe word eigenstates is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.\nHighest Scoring Words With Friends™ Play In The Letters eigenstates :\nAll Words With Friends™ Plays For The Word eigenstates\nThe 200 Highest Scoring Words With Friends™ Plays Using The Letters In eigenstates\nWords within the letters of eigenstates\n2 letter words in eigenstates (10 words)\n3 letter words in eigenstates (33 words)\n4 letter words in eigenstates (58 words)\n5 letter words in eigenstates (62 words)\n6 letter words in eigenstates (52 words)\n7 letter words in eigenstates (30 words)\n8 letter words in eigenstates (16 words)\n9 letter words in eigenstates (3 words)\n10 letter words in eigenstates (1 word)\n11 letter words in eigenstates (1 word)\neigenstates + 2 blanks (1 word)\nWords containing the sequence eigenstates\nWords that start with eigenstates (1 word)\nWords with eigenstates in them (1 word)\nWords that end with eigenstates (1 word)\nWord Growth involving eigenstates\nShorter words in eigenstates\nen ens eigenstate\nat ate state eigenstate\nat stat state eigenstate\nta stat state eigenstate\nLonger words containing eigenstates\nWord analysis of <q>eigenstates</q>, at www.litscape.com\nWord analysis of eigenstates , at www.litscape.com


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It kin realisearje automatisearring, paperless, fisualisaasje, graphics, ynformaasje, aktualiteit, precision, en grien.\n2. Ferbettere operaasje effisjinsje, tydlike en krekte gegevens, kostenreduksje, miljeutemperatuer en feiligensmonitoring, en fermindere ferlies.\n3. 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De ferzje fan 20 jul 2014 om 18.06\nDe ferzje fan 20 jul 2014 om 14.59 (wizigje)\nDe ferzje fan 20 jul 2014 om 18.06 (wizigje) (weromsette)\n'''Parafily''' (fan it [[Gryksk]] ''para'' παρά = neist en ''-philia'' φιλία = freonskip, hjir leafde) is in begryp yn de seksuology en psychology dy’t in seksueleseksuële driuw mei objekten en situaasjes ferbynt dy’t ôfwykt fan de gongbere noarm yn de mienskip. De ôfwikende seksueleseksuële praktiken kinne ridlik ûnskuldich wêze, mar ek tsjin it morbide oan sitte. As in persoan yn syn deistige libben hinder hat fan syn seksuale driuw kin der sprake wêze fan in psychyske sykte.\nFoar klinisy is net elke parafily fan belang, of it moat in beheining wêze foar it funksjonearjen fan de persoan. Yn de [[Diagnostic and Statistical Manual of Mental Disorders|DSM-IV]] wurde ferskate parafilyën neamd. Dêrneist is der noch in groep parafilyën dy’t net yn de DSM-IV steane, mar as dy ta in beheining oangeande it funksjonearjen fan de persoan wêze soenen kin der likegoed sprake wêze fan in psychyske ôfwiking.\nYn de [[Diagnostic and Statistical Manual of Mental Disorders|DSM-IV]] steane de neikommende parafilyën omskreaun<ref>[http://www.psyonline.nl/parafilieen.html List mei parafilyënparafilyen op psyonline.nl]</ref>:\nYn it hânboek DSM-IV stiet ek in restgroep sûnder neiere omskriuwing. Under dy restgroep falle [[nekrofily]] (liken), [[klismafily]] (rektaal ynbringen fan floeistof), [[koprofily]] (ûntlêsting), telefoankatalogy (obseniteiten oer de telefoan), [[urofily]] (urine) en [[partialisme]] (lichemsdielen). Troch de ûnderlizzende seksueleseksuële driuw soe [[apotemnofily]] bygelyks (djip langstme nei it amputearjen fan sûne lichemsdielen, gauris sûnder medysk tafersjoch of oare begelieding) ta it partialisme rekkene wurde kinne.\nYn de psychology en psychiatry binne ferskate tsjinlûden oer de klassifikaasje fan parafilyën as psychyske sykten. Der is in groep dy’t úthâld dat de klassifikaasje te bot hinget op maatskiplike noarmen en ideeën. Homofily wie bygelyks in selsstannige parafily yn de DSM-II, sadat der in diagnoaze jûn wurde koe as de eigen homoseksualiteit oer in langere tiid problematyske gefolgen hie. Yn de aktueleaktuële DSM-IV-TR stiet in diagnoazekategory „net"net neier omskreaune seksueleseksuële steuring “" dêr’t ek in yngong „duorsum"duorsum en dúdlik lijen oan de seksuele[[seksuële oriïntearring “]]" yn stiet.\nUntfongen fan "https://fy.wikipedia.org/wiki/Wiki:MobileDiff/695996"


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Access is denied. Escalating U.S. role in Syria, Trump orders strikes on Assad airbase\nWASHINGTON/PALM BEACH, Fla. (Reuters) - U.S. President Donald Trump said on Thursday he ordered missile strikes against a Syrian airfield from which a deadly chemical weapons attack was launched, declaring he acted in America's "vital national security interest" against Syrian President Bashar al-Assad.\n(Additional reporting by Phil Stewart, Idrees Ali, Yara Bayoumy, Jonathan Landay, John Walcott, Lesley Wroughton, Patricia Zengerle, David Brunnstrom and Matt Spetalnick in Washington and Megan Davies in New York; Writing by Matt Spetalnick and Jeff Mason; Editing by Yara Bayoumy and Peter Cooney)


Auto Auction Ended on VIN: JTDJTUD3XCD511574 2012 Toyota Yaris in Candia, NH Welcome, Guest! Log In\n: off Add to Watchlist Lot # 325514362012 TOYOTA YARIS 1.5L 4 4 for Sale at\nTHIS VEHICLE IS BEING SOLD AS "AS IS - WHERE IS" - ALL BIDS ARE BINDING AND ALL SALES ARE FINAL What this means Copart Auto Auction TOYOTA Lot Details Lot # 32551436 Est. Retail Value $8,775 USD Repair Est $13,052 USD Ownership Doc Type NH\n- CERT OF TITLE-SALVAGE Odometer 0 NOT ACTUAL Primary Damage FRONT END Secondary Damage BIOHAZARD/CHEMICAL VIN JTDJTUD3XCD511574 Body Style HATCHBAC Color GRAY Engine 1.5L 4 4 Drive Front-wheel Drive Cylinders 4 Fuel GAS Keys YES Bid Information Auction Location Candia, NH show on map Sale Date Tuesday, October 25, 2016 Live Auction Starts 07:00 AM Pacific Standard Time Live Auction Item Lane B - Item # 2542\nShowing 12 of 388 2011 TOYOTA YARIS Auction: Wheeling, IL Current Bid:\n$0 USD 2015 TOYOTA YARIS Auction: West Warren, MA Time Left:\n$0 USD 2011 TOYOTA YARIS Auction: Raleigh, NC Current Bid:\n$500 USD 2011 TOYOTA YARIS Auction: Savannah, GA Current Bid:\n$0 USD 2012 TOYOTA YARIS Auction: Greer, SC Current Bid:


Ellesse Magdalena Tanktop Dames - Donkerblauw, Mauve online kopen | Tennis-Point\nMagdalena Tanktop Dames - Donkerblauw, Mauve\nArt. Nr.: 00244801368000


Thús » Lêste nijs artikels » Airlines » Serieus Nice flechten no op A220-300\nAirlines • Loftfeart • Breaking Reisnijs • Nijs • Technology • Reisbestimmingsupdate • Travel Wire Nijs • USA Breaking News\nBreeze Airways, is in Amerikaanske loftfeartmaatskippij mei haadkantoar yn Cottonwood Heights, Utah.\nDe loftline waard oprjochte troch David Neeleman, dy't earder mei-oprjochter Morris Air, WestJet, JetBlue, en Azul Linhas Ahere wie.\nBreeze Airways hat har nije iepenbiere A220-300 livery wylst befêstiget dat it in oankeapsoerienkomst hat berikt mei Airbus foar 20 mear fan it fleantúch.\nDizze earder net iepenbiere oarder foar 20 bringt it totale bestelboek fan Breeze op 80 A220-300s, wêrfan de earste sil wurde levere yn Q4 2021.\nDe frisse fervebaan fan it fleantúch waard foltôge by Airbus 'foarsjenning yn Mobile, Alabama, dy't sawat ien A220 per moanne sil leverje oan Breeze oer de kommende seis-en-in-heal jier.\nBreeze Airways, in Amerikaanske regionale loftfeartmaatskippij sei oer it bedriuw: "Wy binne in team fan loftfeart-, gastfrijheids- en technologyleafhawwers dy't leauwe dat fleanen it grutste privileezje en kâns yn 'e wrâld is. En, wy leauwe dat it in tagonklike en echt leuke ûnderfining foar elkenien moat wêze. ”\n"Tegearre hawwe wy makke Breeze Airways ™ - in nije loftfeartmaatskippij fuseart technology mei freonlikens. Breeze biedt non -stop tsjinst tusken net -betsjinne rûtes oer de FS tsjin betelbere tariven.\n“Mei naadleaze boeking, gjin feroarings- as annulearingsfergoedingen en oanpaste flechtfunksjes levere fia in slanke en ienfâldige app, makket Breeze it maklik te keapjen en maklik te fleanen. Wolkom by Breeze, Seriously Nice ™ flechten en tariven. ”\nDe loftline is fan plan om flechten te begjinnen mei de Airbus -float yn it twadde kwartaal fan 2022.\nBreeze Air stêden\nDe superieure effisjinsje A220 sil de saaklike doelstellingen fan 'e nije loftline stypje om in geweldige reisûnderfining oan te bieden, mei lege tariven en hege fleksibiliteit. Breeze wurdt ferwachte dat se non -stop tsjinst sil leverje tusken net -betsjinne rûtes oer de FS tsjin betelbere tariven.\nBreeze begon mei loftfeartbedriuwen yn maaie 2021. Dizze earste A220 is it earste nije fleantúch dat sil wurde betsjinne troch de loftline.\nDe A220 is it ienige fleantúch dat spesjaal is boud foar de 100-150 sitmarkt en bringt state-of-the-art aerodynamika, avansearre materialen en Pratt & Whitney's nijste generaasje PW1500G gearbiede turbofanmotors. Profitearje fan 'e lêste technologyen, de A220 is it stilste, skjinste en meast miljeufreonlike fleantúch yn syn kategory.\nMei in 50% fermindere lûdfoetôfdruk en oant 25% legere brânstofferbrâning per stoel fergelike mei eardere fleanmasines, lykas sawat 50% legere NOx -útstjit dan yndustrystandards, is de A220 in geweldich fleantúch foar stedske operaasjes.\nMear dan 170 A220's binne levere oan tsien operators yn Aazje, Noard -Amearika, Jeropa en Afrika, wat de grutte alsidichheid bewiist fan it lêste famyljelid fan Airbus.


Cojin Abstract Painting No. 17 – Impresionarte - The ArtShop\nInicio » Cojines » Cojin Abstract Painting No. 17\nCOJIN ABSTRACT PAINTING NO. 17