TWAS hub - RPAP1\n1 CommonMind Brain Pre-frontal Cortex 0.0950 0.0330 3.2e-07 0.095 0.053 0.083 0.065 0.089 1.4e-11 4.9e-07 2.8e-10 2.5e-08 5.1e-11\n2 GTEx Adipose Subcutaneous 0.1830 0.0410 1.6e-11 0.204 NA 0.211 NA 0.209 1.4e-16 NA 4.3e-17 NA 5.5e-17\n3 GTEx Artery Aorta 0.2180 0.0590 8.3e-07 0.155 NA 0.152 NA 0.164 6.9e-09 NA 9.6e-09 NA 2.4e-09\n4 GTEx Artery Coronary 0.2200 0.0740 1.2e-04 0.113 NA 0.080 NA 0.103 1.2e-04 NA 1.1e-03 NA 2.5e-04\n5 GTEx Artery Tibial 0.2701 0.0539 3.7e-14 0.269 NA 0.284 NA 0.284 3.3e-21 NA 1.7e-22 NA 1.9e-22\n6 GTEx Brain Cerebellum 0.1620 0.0630 9.0e-04 0.098 NA 0.073 NA 0.125 8.1e-04 NA 3.5e-03 NA 1.6e-04\n7 GTEx Brain Cortex 0.2730 0.0850 7.6e-05 0.217 NA 0.179 NA 0.194 1.2e-06 NA 1.2e-05 NA 4.8e-06\n8 GTEx Brain Hippocampus 0.2959 0.1133 6.4e-03 0.149 NA 0.192 NA -0.010 2.4e-04 NA 2.8e-05 NA 6.2e-01\n9 GTEx Breast Mammary Tissue 0.1520 0.0570 5.1e-04 0.144 NA 0.157 NA 0.150 7.9e-08 NA 1.9e-08 NA 4.0e-08\n10 GTEx Breast Mammary Tissue (Male) 0.0138 0.0473 4.1e-01 -0.013 NA 0.014 NA -0.013 8.6e-01 NA 1.5e-01 NA 8.8e-01\n11 GTEx Breast Mammary Tissue (Female) 0.2673 0.1143 4.3e-03 0.111 NA 0.157 NA 0.184 3.4e-04 NA 2.0e-05 NA 3.8e-06\n12 GTEx Cells EBV-transformed lymphocytes 0.1870 0.0600 2.8e-05 0.226 NA 0.203 NA 0.207 6.1e-08 NA 3.4e-07 NA 2.5e-07\n13 GTEx Cells Transformed fibroblasts 0.3710 0.0550 0.0e+00 0.424 NA 0.424 NA 0.427 2.9e-34 NA 2.8e-34 NA 1.2e-34\n14 GTEx Colon Sigmoid 0.1460 0.0690 5.8e-03 0.016 NA 0.015 NA 0.013 9.0e-02 NA 9.4e-02 NA 1.1e-01\n15 GTEx Colon Transverse 0.3560 0.0740 2.3e-10 0.248 NA 0.283 NA 0.316 3.7e-12 NA 6.7e-14 NA 1.4e-15\n16 GTEx Esophagus Gastroesophageal Junction 0.2690 0.0920 5.0e-05 0.120 NA 0.138 NA 0.174 4.1e-05 NA 1.1e-05 NA 7.0e-07\n17 GTEx Esophagus Mucosa 0.2790 0.0560 1.9e-12 0.201 NA 0.236 NA 0.221 1.7e-13 NA 8.3e-16 NA 7.6e-15\n18 GTEx Esophagus Muscularis 0.3230 0.0590 2.8e-16 0.289 NA 0.293 NA 0.295 6.8e-18 NA 3.8e-18 NA 2.9e-18\n19 GTEx Heart Left Ventricle 0.0887 0.0401 1.9e-03 0.072 NA 0.025 NA 0.047 1.2e-04 NA 1.7e-02 NA 1.6e-03\n20 GTEx Lung 0.1721 0.0488 5.8e-09 0.124 NA 0.157 NA 0.149 9.7e-10 NA 4.3e-12 NA 1.6e-11\n21 GTEx Muscle Skeletal 0.0760 0.0251 4.0e-06 0.121 NA 0.108 NA 0.110 6.4e-12 NA 9.5e-11 NA 6.4e-11\n22 GTEx Nerve Tibial 0.2627 0.0559 2.8e-13 0.208 NA 0.165 NA 0.194 1.1e-14 NA 8.9e-12 NA 9.6e-14\n23 GTEx Ovary 0.2280 0.1040 7.6e-03 0.113 NA 0.005 NA 0.011 1.0e-03 NA 2.4e-01 NA 1.7e-01\n24 GTEx Pancreas 0.2230 0.0690 5.0e-04 0.114 NA 0.098 NA 0.129 1.6e-05 NA 6.5e-05 NA 4.2e-06\n25 GTEx Skin Not Sun Exposed Suprapubic 0.3690 0.0860 8.2e-08 0.167 NA 0.191 NA 0.018 1.9e-09 NA 1.1e-10 NA 3.4e-02\n26 GTEx Skin Sun Exposed Lower leg 0.3150 0.0540 0.0e+00 0.232 NA 0.304 NA 0.300 4.5e-19 NA 1.3e-25 NA 3.8e-25\n27 GTEx Spleen 0.2040 0.0860 1.5e-03 0.087 NA 0.056 NA 0.045 3.1e-03 NA 1.5e-02 NA 2.6e-02\n28 GTEx Stomach 0.4100 0.0860 3.6e-07 0.250 NA 0.219 NA 0.240 2.6e-12 NA 8.1e-11 NA 8.3e-12\n29 GTEx Testis 0.1240 0.0540 9.5e-04 0.120 NA 0.092 NA 0.078 5.7e-06 NA 6.7e-05 NA 2.4e-04\n30 GTEx Thyroid 0.1380 0.0470 1.1e-05 0.072 NA 0.101 NA 0.121 3.4e-06 NA 3.9e-08 NA 1.7e-09\n31 GTEx Vagina 0.1830 0.0810 4.2e-03 0.282 NA 0.167 NA 0.232 3.4e-07 NA 1.2e-04 NA 4.8e-06\n32 METSIM Adipose 0.1086 0.0296 1.9e-13 0.119 0.095 0.116 0.081 0.097 2.3e-17 4.0e-14 7.0e-17 4.1e-12 2.4e-14\n33 NTR Blood 0.0250 0.0103 3.7e-04 0.016 0.009 0.016 0.009 0.014 5.4e-06 5.5e-04 3.5e-06 3.9e-04 1.7e-05\n34 YFS Blood 0.0780 0.0189 0.0e+00 0.096 0.067 0.094 0.093 0.094 1.4e-29 4.3e-21 4.4e-29 8.8e-29 3.6e-29\n35 TCGA Bladder Urothelial Carcinoma 0.1220 0.0470 9.5e-10 0.130 0.132 0.118 NA 0.120 3.9e-11 2.8e-11 3.3e-10 NA 2.3e-10\n36 TCGA Breast Invasive Carcinoma 0.0782 0.0239 0.0e+00 0.099 0.126 0.126 NA 0.123 1.3e-19 8.4e-25 7.8e-25 NA 3.3e-24\n37 TCGA Cervical Squamous Cell Carcinoma 0.0420 0.0240 8.8e-03 0.002 0.029 0.016 NA 0.009 2.4e-01 1.4e-02 5.4e-02 NA 1.1e-01\n38 TCGA Colon Adenocarcinoma 0.1490 0.0560 9.6e-10 0.171 0.167 0.164 NA 0.018 3.8e-10 6.2e-10 9.7e-10 NA 2.9e-02\n39 TCGA Head and Neck Squamous Cell Carcinoma 0.0987 0.0321 3.0e-15 0.090 0.141 0.125 NA 0.133 2.8e-10 1.3e-15 7.3e-14 NA 1.1e-14\n40 TCGA Kidney Renal Clear Cell Carcinoma 0.1114 0.0354 8.8e-15 0.124 0.112 0.117 NA 0.116 7.9e-14 1.3e-12 4.8e-13 NA 6.3e-13\n41 TCGA Kidney Renal Papillary Cell Carcinoma 0.0990 0.0460 1.8e-05 0.071 0.057 0.067 NA 0.067 7.0e-05 3.5e-04 1.0e-04 NA 1.1e-04\n42 TCGA Brain Lower Grade Glioma 0.1234 0.0380 0.0e+00 0.202 0.202 0.223 NA 0.227 1.7e-22 1.9e-22 5.5e-25 NA 2.2e-25\n43 TCGA Lung Adenocarcinoma 0.1252 0.0461 2.1e-15 0.146 0.135 0.134 NA 0.138 1.0e-16 1.6e-15 2.0e-15 NA 7.3e-16\n44 TCGA Lung Squamous Cell Carcinoma 0.0593 0.0252 1.1e-07 0.086 0.064 0.080 NA 0.049 5.4e-10 9.4e-08 2.3e-09 NA 3.0e-06\n45 TCGA Ovarian Serous Cystadenocarcinoma 0.0730 0.0340 1.0e-04 0.022 0.037 0.034 NA 0.024 1.2e-02 1.5e-03 2.2e-03 NA 9.5e-03\n46 TCGA Pancreatic Adenocarcinoma 0.1680 0.0920 5.5e-04 0.045 0.085 0.059 NA 0.057 5.7e-03 1.9e-04 1.7e-03 NA 2.1e-03\n47 TCGA Pheochromocytoma and Paraganglioma 0.1240 0.0580 2.3e-04 0.084 0.082 0.086 NA 0.092 3.2e-04 3.6e-04 2.8e-04 NA 1.7e-04\n48 TCGA Prostate Adenocarcinoma 0.0984 0.0344 5.8e-12 0.115 0.100 0.121 NA 0.116 4.7e-12 1.4e-10 1.3e-12 NA 3.9e-12\n49 TCGA Rectum Adenocarcinoma 0.3710 0.1380 1.3e-03 0.103 0.083 0.027 NA 0.050 2.2e-03 5.5e-03 7.6e-02 NA 2.6e-02\n50 TCGA Soft Tissue Sarcoma 0.2040 0.0820 1.0e-06 0.063 0.110 0.130 NA 0.112 1.3e-04 4.6e-07 4.0e-08 NA 3.5e-07\n51 TCGA Stomach Adenocarcinoma 0.1290 0.0490 1.3e-07 0.110 0.105 0.116 NA 0.112 2.4e-08 5.3e-08 1.0e-08 NA 1.9e-08\n52 TCGA Testicular Germ Cell Tumors 0.1930 0.0740 1.8e-04 0.150 0.074 0.077 NA 0.104 5.7e-06 1.3e-03 1.1e-03 NA 1.7e-04\n53 TCGA Thyroid Carcinoma 0.1400 0.0410 4.4e-15 0.142 0.158 0.182 NA 0.161 1.1e-13 3.4e-15 1.9e-17 NA 1.9e-15\nBipolar Disorder (2018) 1.8 2.8 8.9 1.2 1.7 1.8 1.5 1.7 1.5 1.6 0.4 1.6 1.4 1.6 1.5 1.4 0.8 1.6 1.5 1.3 2.1 1.9 1.8 1.4 1.7 1.1 0.9 2.4 1.8 1.6 1.3 2.1 1.6 1.2 1.1 1.2 0.5 1.4 1.4 2.9 2.0 2.3 2.4 1.2 2.1 1.6 1.4 1.3 1.6 1.0 1.9 2.1 3.0 2.1 1.8 1.6\nBipolar Disorder or Schizophrenia 0.1 0.3 2.6 -0.3 0.5 0.4 0.4 0.4 0.6 0.3 -1.6 0.3 0.0 0.2 0.0 -0.0 0.1 0.3 0.0 0.8 0.6 0.7 0.3 -0.2 0.2 -0.3 -0.4 1.0 0.5 0.4 -0.1 0.5 0.0 -0.3 0.0 -0.5 -0.6 0.2 -0.1 0.9 0.6 0.6 0.9 0.0 0.5 -0.1 0.0 0.1 0.5 0.3 0.3 1.2 1.0 0.6 0.9 0.1\nDepressed Affect (Nagel 2018) 0.6 1.2 3.2 -1.4 -1.3 -1.0 -1.1 -1.5 -0.4 -0.5 1.0 -0.7 -1.3 -1.7 -1.5 -1.4 -0.1 -0.6 -1.0 -1.1 -1.4 -0.1 -0.8 -1.5 -0.9 -1.0 -1.5 -1.0 -1.4 -0.5 -1.6 -0.2 -0.8 -1.4 -1.4 -1.0 -1.3 -0.6 -0.5 -0.5 -0.6 -1.0 -0.6 -1.6 -1.1 -1.0 -1.4 -1.1 -1.8 -1.4 -1.0 0.6 -0.5 -0.5 -0.8 -0.7\nDepression (Nagel 2018) 0.4 0.7 1.8 -1.0 -0.7 -0.8 -0.8 -1.0 -0.6 -0.5 0.7 -0.8 -0.9 -1.3 -1.0 -1.0 -0.3 -0.5 -0.6 -0.4 -1.0 -0.5 -0.9 -1.0 -0.5 -1.3 -0.9 -1.0 -0.9 -0.5 -1.2 -0.6 -0.5 -1.0 -0.9 -0.5 -0.7 -0.9 -1.2 -0.3 -0.6 -0.7 -0.5 -1.1 -0.7 -0.8 -1.0 -0.8 -1.0 -0.6 -0.8 -0.0 -0.6 -0.1 -0.8 -0.9\nIntelligence (Savage-Jansen 2018) 1.7 5.2 13.5 2.4 2.8 2.8 1.6 2.6 2.5 2.3 2.6 1.8 2.0 2.5 2.1 2.1 2.7 2.0 2.3 2.9 1.7 1.1 2.5 2.2 2.7 1.7 2.9 1.8 3.0 1.9 2.3 1.9 2.7 2.2 2.6 2.6 3.7 2.6 2.0 1.2 2.6 1.9 1.4 2.3 2.0 2.4 2.2 2.7 2.6 3.4 1.7 1.6 0.1 0.9 2.0 2.0\nNeuroticism (Nagel 2018) 0.9 2.0 4.9 -1.9 -1.3 -1.0 -1.4 -1.6 -0.7 -1.0 0.6 -1.2 -1.8 -1.9 -1.8 -2.0 -0.4 -0.9 -1.7 -1.1 -1.7 -0.7 -1.3 -2.2 -1.2 -1.3 -1.9 -1.5 -1.6 -1.1 -2.1 -0.7 -1.2 -1.9 -1.6 -1.8 -1.3 -1.4 -1.5 -0.9 -0.8 -1.1 -0.8 -2.0 -1.4 -1.6 -1.7 -1.8 -1.6 -1.8 -1.5 0.1 -0.4 -0.7 -0.2 -1.5\nSchizophrenia (2018) 0.5 1.1 6.0 -1.4 -0.7 -0.9 -0.7 -0.9 -0.5 -1.0 -2.5 -0.8 -1.1 -1.0 -1.2 -1.2 -0.5 -0.9 -1.2 -0.0 -1.0 -0.6 -1.1 -1.4 -1.1 -1.2 -1.2 -0.7 -0.8 -0.8 -1.1 -1.1 -1.3 -1.4 -0.9 -1.6 -1.1 -0.9 -1.3 -1.1 -0.8 -1.0 -0.8 -0.9 -1.0 -1.4 -1.1 -1.0 -0.7 -0.5 -1.1 -0.2 -1.1 -0.9 -0.2 -1.2\nSchizophrenia vs Biploar Disorder 0.2 0.3 2.2 -0.0 -0.1 0.0 -0.4 -0.2 0.0 -0.0 -1.2 -0.6 -0.4 -0.0 -0.2 -0.2 0.5 -0.3 -0.2 0.1 -0.7 -0.6 -0.2 -0.0 -0.6 0.5 -0.5 -0.9 -0.2 -0.4 0.1 -0.4 -0.4 -0.1 -0.2 -0.6 -0.2 0.3 -0.2 -1.0 -0.7 -1.3 -0.7 -0.3 -0.4 -0.3 -0.2 -0.2 -0.6 -0.3 -0.5 0.4 -1.5 -0.7 -0.5 -0.3\nWorry (Nagel 2018) 0.2 0.3 0.9 -0.8 -0.1 -0.3 -0.8 -0.4 0.1 -0.3 0.7 -0.3 -0.9 -0.5 -0.6 -0.8 0.6 0.1 -0.8 -0.1 -0.7 -0.4 -0.4 -1.0 -0.4 0.2 -0.7 -0.6 -0.4 -0.6 -0.9 -0.3 -0.5 -0.9 -0.4 -0.9 -0.1 -0.7 -0.7 -0.4 -0.1 -0.4 -0.3 -0.7 -0.8 -0.7 -0.7 -0.8 -0.5 -0.5 -0.6 0.8 -0.5 0.3 0.5 -0.9\nAlzheimer’s Disease (in mother) 0.7 0.8 2.8 -1.2 -0.5 -0.5 -1.4 -0.6 -0.3 -1.0 -1.3 -0.7 -1.4 -0.6 -0.8 -1.1 -0.0 -0.9 -0.2 -0.3 -0.8 -1.4 -1.0 -1.1 -0.5 -0.4 -0.2 -1.3 -0.5 -1.6 -0.9 -1.1 -0.7 -1.3 -0.4 -0.7 0.5 -1.1 -0.9 -0.5 -0.4 -0.3 -1.2 -0.8 -1.1 -1.0 -1.1 -0.4 -0.3 0.5 -1.2 -0.8 -1.2 -1.7 0.6 -1.1\nAlzheimer’s Disease (in father) 3.1 3.4 13.5 1.6 1.8 1.8 1.3 1.5 1.6 2.1 2.2 1.1 1.4 1.4 1.5 1.6 1.3 1.8 1.8 1.2 2.1 2.1 2.5 1.7 1.6 1.9 0.4 2.4 1.7 2.0 1.5 2.4 2.0 1.6 1.2 1.8 0.8 1.4 1.6 2.6 1.8 2.4 2.2 1.2 2.3 2.0 1.5 1.4 1.4 0.9 2.0 1.9 3.7 3.0 1.1 1.7\nAlzheimer’s Disease (including proxy) 0.2 0.2 0.8 -0.8 -0.3 -0.2 -0.9 -0.3 -0.2 -0.5 -0.6 -0.4 -0.7 -0.3 -0.5 -0.6 -0.3 -0.5 0.3 -0.2 -0.2 -0.8 -0.1 -0.6 -0.2 0.1 -0.5 -0.5 -0.2 -0.9 -0.5 -0.5 -0.3 -0.8 -0.4 -0.3 0.1 -0.8 -0.6 0.6 -0.1 0.4 -0.2 -0.6 -0.2 -0.4 -0.6 -0.3 -0.2 0.4 -0.5 -0.1 0.7 -0.2 0.2 -0.7\nCrohns Disease (2017) 0.2 0.4 1.8 0.8 0.6 0.8 0.8 0.6 0.7 1.0 0.5 0.4 0.9 0.4 0.5 0.8 -0.1 0.3 0.7 0.1 0.5 1.0 0.9 0.9 0.6 0.4 0.3 0.7 0.6 0.9 0.6 1.0 0.6 0.9 0.3 0.2 -0.0 1.0 0.8 0.0 0.4 -0.0 0.7 0.5 0.9 0.8 0.8 0.4 0.2 -0.3 0.9 0.5 0.3 -0.3 0.3 1.3\nIrritable Bowel Disease (IBD) 1.2 3.0 6.3 1.5 1.5 1.9 1.8 1.6 1.8 2.1 0.0 1.9 1.7 1.3 1.7 1.7 1.0 1.4 1.9 1.3 2.0 2.4 1.9 1.7 1.9 1.4 0.9 2.5 1.7 2.0 1.5 2.5 1.7 1.6 1.0 1.2 0.4 1.7 1.8 2.3 1.8 1.8 2.4 1.3 2.2 1.7 1.7 1.6 1.2 0.7 2.1 2.0 1.8 1.3 1.7 2.3\nUlcerative Colitis (UC) 2.5 4.7 11.5 1.9 1.7 2.1 2.2 1.9 2.1 2.5 -0.0 2.4 2.0 1.6 2.2 2.1 1.7 1.9 2.4 1.8 2.8 2.8 2.0 2.0 2.5 1.7 1.1 3.3 1.9 2.3 1.8 3.0 2.1 1.9 1.3 1.7 0.5 1.7 2.0 3.4 2.3 2.9 3.0 1.6 2.7 2.1 2.0 1.9 1.5 1.1 2.6 2.6 2.7 2.4 2.1 2.3\nMajor Depression (MDD) 1.6 2.0 5.9 -1.5 -1.3 -0.9 -1.0 -1.5 -1.3 -0.8 -0.8 -1.4 -0.6 -1.6 -1.4 -1.2 -1.2 -1.4 -1.7 -1.7 -1.6 -0.5 -1.6 -1.2 -1.3 -1.3 -2.0 -1.1 -1.5 -1.0 -1.5 -0.6 -1.3 -1.3 -1.7 -2.0 -2.2 -1.1 -1.3 -1.7 -1.6 -2.1 -0.7 -1.5 -1.1 -1.2 -1.1 -1.3 -1.9 -2.2 -1.1 -0.5 -2.4 -1.2 -1.2 -0.7\nReaction Time 0.6 1.1 6.5 -0.6 -0.9 -0.9 -0.3 -1.1 -1.4 -0.5 -1.2 -0.8 -0.6 -1.1 -0.6 -0.6 -1.0 -0.9 -1.1 -1.6 -0.8 0.2 -1.4 -0.5 -1.1 -0.9 -1.4 -0.4 -1.6 -0.8 -0.7 -0.3 -0.9 -0.3 -1.5 -1.6 -2.1 -0.7 -1.2 -1.0 -1.2 -1.7 -0.2 -1.1 -0.5 -0.5 -0.6 -1.4 -1.3 -2.5 -0.3 -0.4 -1.0 -0.4 -1.3 -0.0\nVerbal and Numeric Reasoning (VNR) 1.1 2.5 9.3 1.8 1.8 1.8 0.7 1.7 1.5 1.4 2.2 1.7 1.4 1.7 1.6 1.5 1.7 1.3 2.1 2.0 1.0 -0.1 1.7 1.7 2.0 1.0 2.1 0.7 2.1 1.1 1.8 0.8 1.8 1.7 1.8 2.0 3.1 1.4 0.9 0.9 1.6 1.4 0.7 1.5 1.5 1.6 1.6 1.8 1.9 2.8 1.0 0.9 -0.2 0.8 0.7 0.9\nBreast Cancer 0.1 0.2 2.7 -0.4 0.4 0.5 0.0 0.5 0.5 -0.2 -0.5 0.9 -0.6 0.4 -0.0 -0.3 0.3 0.3 -0.1 0.8 -0.0 -0.1 0.2 -0.4 0.3 1.0 0.1 0.8 0.5 -0.3 0.1 -0.1 -0.2 -0.4 0.1 -0.6 0.1 0.0 -0.2 -0.4 0.3 -0.0 0.0 0.1 -0.3 -0.3 -0.1 0.1 0.5 0.3 -0.4 0.5 -1.3 -0.3 1.6 -0.1\nOvarian Cancer 1.8 2.4 5.0 -1.4 -1.5 -1.5 -1.5 -1.8 -1.5 -1.4 -0.0 -1.3 -1.7 -1.3 -1.8 -1.6 -0.9 -1.3 -2.0 -1.7 -1.9 -1.4 -1.6 -1.5 -1.8 -0.9 -0.8 -2.2 -1.9 -1.4 -1.5 -1.7 -1.2 -1.5 -1.4 -1.0 -0.8 -1.4 -1.3 -2.2 -1.7 -2.0 -2.0 -1.6 -1.8 -1.4 -1.6 -1.3 -1.5 -1.3 -1.7 -1.9 -1.8 -1.6 -1.6 -1.3\nProstate Cancer 0.3 0.5 4.5 0.5 0.4 0.7 0.7 0.7 0.5 0.5 -0.9 0.6 0.4 0.7 0.7 0.6 0.8 0.8 0.2 0.4 0.9 0.5 0.4 0.5 0.7 0.1 1.1 1.1 0.5 0.5 0.6 0.6 0.4 0.5 0.7 0.4 0.4 0.2 0.5 0.3 0.8 1.3 0.6 0.8 0.5 0.5 0.6 0.2 1.0 0.5 0.6 0.1 2.1 0.4 1.2 0.2\nAge at First Birth 2.4 3.5 8.5 1.9 1.7 1.9 1.6 1.9 1.9 1.8 2.3 1.6 1.8 1.7 1.8 1.8 2.0 1.6 2.2 2.0 1.9 1.4 1.9 1.7 2.3 1.2 2.9 1.6 2.1 1.7 2.0 1.7 2.1 1.8 2.1 2.5 2.6 1.7 2.0 1.4 1.6 2.1 1.2 2.0 1.9 1.9 2.0 2.1 1.9 2.3 1.8 0.8 1.6 0.5 1.8 1.6\nBipolar Disorder (2011) 0.9 0.8 3.6 -1.2 -1.0 -1.0 -1.1 -0.9 -1.1 -1.2 -1.0 -1.1 -1.1 -1.2 -1.2 -1.2 -1.9 -0.9 -1.2 -0.9 -0.9 -0.9 -0.9 -1.3 -1.2 -0.8 -1.6 -0.3 -1.0 -1.2 -1.2 -0.9 -1.2 -1.2 -1.2 -1.5 -1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0\nBody Mass Index (BMI) (2010) 1.7 2.3 8.1 -1.5 -1.3 -1.4 -1.5 -1.5 -1.2 -1.5 -1.1 -1.7 -1.7 -1.8 -1.8 -1.8 -1.5 -1.7 -1.5 -1.1 -1.9 -1.3 -1.0 -1.8 -1.6 -0.2 -1.7 -1.0 -1.1 -1.5 -1.8 -1.5 -1.3 -1.6 -1.4 -1.1 -0.5 -1.0 -1.0 -1.8 -1.5 -1.9 -2.0 -1.7 -1.8 -1.5 -1.6 -0.8 -1.6 -0.5 -1.7 -1.4 -2.8 -2.2 -1.4 -1.0\nCoronary Artery Disease (CAD) 0.2 0.2 1.0 0.5 0.6 0.2 0.2 0.6 0.4 0.4 0.9 0.1 0.5 0.3 0.5 0.6 1.0 0.5 0.5 0.3 0.5 0.1 0.1 0.7 0.5 -0.3 0.3 0.1 0.3 0.3 0.6 0.1 0.5 0.5 0.8 0.6 0.8 -0.1 0.1 0.1 0.2 0.5 0.1 0.6 0.2 0.5 0.4 0.2 0.5 0.1 0.2 -0.4 0.7 0.8 0.1 -0.0\nCrohns Disease (2012) 1.0 1.6 3.1 1.3 1.4 1.4 1.3 1.4 1.5 1.6 0.7 1.2 1.2 1.0 1.1 1.2 0.5 1.1 1.6 1.1 1.1 1.6 1.8 1.3 1.2 1.2 0.4 0.9 1.6 1.6 1.1 1.5 1.3 1.2 0.8 1.0 0.5 1.7 1.4 1.1 1.5 1.1 1.4 1.0 1.5 1.3 1.3 1.3 1.1 1.1 1.4 1.6 0.8 0.5 1.2 1.7\nMean Putamen Volume 0.5 0.6 1.5 -0.7 -0.5 -0.8 -0.7 -0.6 -0.2 -0.4 -0.2 -0.5 -0.9 -1.2 -0.8 -0.7 -0.3 -0.7 -0.7 -0.8 -0.9 -0.4 -0.6 -0.6 -0.7 -0.3 -0.9 -0.6 -0.7 -0.7 -0.9 -0.5 -0.8 -0.6 -0.9 -1.1 -1.2 -0.6 -0.6 -1.2 -0.9 -0.9 -0.9 -0.9 -0.7 -0.7 -0.7 -0.9 -1.2 -1.2 -0.8 -0.7 -0.8 -1.2 -0.8 -0.5\nFasting Glucose 0.5 0.6 1.4 0.6 -0.6 -0.8 -0.9 -0.7 -1.2 -0.9 -0.7 -0.3 -0.7 -0.9 0.0 -0.5 -1.0 -0.8 -0.3 -0.8 -0.6 -1.0 -0.9 -0.6 -0.6 -0.9 -0.8 -0.4 -0.8 -0.8 0.5 -0.6 -0.9 0.6 -0.6 -0.6 -0.5 -0.6 -1.1 -0.7 -0.7 -0.7 -1.1 -0.6 -0.5 -0.8 -0.2 -0.8 -0.6 -0.7 -0.4 -1.0 -0.9 -0.7 -1.1 -0.6\nHbA1C 0.0 0.1 0.4 -0.3 -0.3 -0.2 -0.1 -0.2 -0.3 -0.5 0.2 -0.6 -0.1 0.0 -0.1 -0.2 -0.4 -0.1 -0.3 0.0 0.1 -0.0 -0.3 -0.4 0.0 -0.6 0.2 0.0 -0.2 0.1 0.2 0.1 -0.2 -0.2 0.1 -0.2 0.1 -0.2 0.0 0.1 -0.2 0.1 -0.0 0.1 -0.1 0.1 -0.1 -0.1 -0.0 -0.4 -0.1 -0.3 0.4 -0.1 0.2 -0.1\nHDL Cholesterol 10.0 16.7 20.9 4.1 4.1 4.3 4.1 4.4 4.6 4.4 2.2 4.2 4.3 4.3 4.3 4.3 4.2 4.2 3.7 4.1 4.4 4.1 4.2 4.2 4.1 3.5 3.9 4.1 4.3 4.3 4.3 4.5 4.1 4.2 4.0 3.6 3.1 4.3 4.1 3.5 4.2 4.1 4.2 4.3 4.5 4.2 4.4 3.9 3.8 3.4 4.4 3.8 4.2 3.1 4.2 4.2\nLDL Cholesterol 0.1 0.1 0.6 0.4 0.2 0.1 0.4 0.3 0.1 0.1 -0.5 0.5 0.6 0.5 0.5 0.5 -0.3 0.1 0.4 0.4 0.4 0.2 0.2 0.5 0.1 0.0 0.7 0.8 0.3 0.2 0.3 0.2 0.3 0.5 0.4 0.6 0.2 0.1 0.5 0.1 -0.1 0.1 0.2 0.6 0.3 0.4 0.5 0.4 0.1 0.0 0.5 -0.2 -0.3 -0.2 0.1 0.5\nLupus 1.9 2.8 5.5 -2.0 -1.7 -1.6 -1.4 -1.7 -1.4 -1.7 -0.7 -2.2 -2.1 -1.9 -2.0 -2.0 -1.6 -1.6 -2.3 -1.1 -1.9 -1.4 -1.7 -2.1 -1.6 -0.7 -1.2 -1.5 -1.6 -1.6 -2.0 -1.6 -1.7 -2.0 -1.5 -1.7 -0.7 -1.9 -1.6 -2.0 -1.2 -1.2 -1.9 -1.9 -2.2 -1.9 -2.0 -1.9 -1.4 -1.2 -1.9 -1.8 -0.9 -1.4 -1.1 -1.8\nNeuroticism (2016) 4.6 6.7 10.4 -3.2 -2.9 -2.1 -2.5 -3.0 -2.3 -2.3 -0.4 -2.5 -2.5 -3.2 -3.1 -3.0 -1.8 -2.7 -2.9 -2.5 -2.8 -1.9 -3.0 -3.2 -2.3 -3.0 -2.5 -2.0 -2.9 -2.4 -3.1 -1.8 -2.4 -3.1 -2.8 -2.7 -2.4 -2.7 -2.4 -2.6 -2.5 -2.6 -2.3 -3.0 -2.6 -2.7 -2.8 -2.6 -2.7 -2.7 -2.6 -2.1 -2.1 -2.6 -1.6 -2.3\nPrimary Biliary Cirrhosis 0.1 0.1 0.5 0.2 -0.3 -0.2 -0.7 -0.1 -0.2 -0.1 -0.1 -0.1 0.0 -0.0 -0.0 0.1 -0.4 0.1 -0.4 -0.7 -0.3 -0.6 -0.2 0.3 -0.3 -0.0 -0.1 -0.1 -0.2 -0.3 0.1 -0.1 -0.3 0.3 -0.2 -0.2 -0.4 -0.2 -0.2 -0.7 -0.4 -0.3 -0.4 -0.1 -0.0 -0.0 0.1 -0.6 -0.6 -0.6 -0.1 -0.4 0.1 -0.4 -0.7 -0.2\nRheumatoid Arthritis 0.7 0.9 3.3 1.1 0.9 0.7 0.9 0.7 0.8 1.3 0.1 0.4 1.1 0.3 1.0 1.0 0.5 0.8 1.0 0.2 0.9 1.1 1.1 1.2 1.0 0.3 -0.5 1.1 0.8 1.2 0.8 1.4 0.9 1.2 0.4 0.8 -0.4 1.2 1.0 1.6 1.2 0.9 1.5 0.6 1.3 1.0 1.0 0.6 0.2 0.4 1.2 1.8 1.2 1.2 0.2 1.3\nSchizophrenia (2014) 0.2 0.5 4.6 -0.8 -0.3 -0.5 -0.3 -0.5 -0.2 -0.4 -2.1 -0.4 -0.5 -0.7 -0.8 -0.7 -0.5 -0.6 -0.4 0.1 -0.7 -0.4 -0.4 -0.7 -0.7 -0.5 -1.2 -0.9 -0.3 -0.4 -0.8 -0.6 -0.8 -0.8 -0.6 -1.0 -0.9 -0.1 -0.9 -0.6 -0.4 -0.9 -0.4 -0.7 -0.5 -0.8 -0.6 -0.7 -0.5 -0.2 -0.7 0.2 -0.7 -0.6 -0.3 -0.7\nTriglycerides 6.2 10.2 18.1 -3.0 -3.3 -3.5 -3.1 -3.3 -3.8 -3.6 -2.0 -2.9 -3.0 -3.1 -3.1 -3.0 -3.4 -3.2 -3.4 -3.2 -3.1 -3.3 -3.8 -3.0 -3.2 -3.0 -2.5 -2.8 -3.5 -3.3 -2.9 -3.6 -3.2 -2.9 -2.7 -2.7 -2.3 -3.8 -3.5 -3.6 -3.6 -3.1 -3.6 -2.9 -3.4 -3.2 -3.1 -3.3 -2.8 -2.9 -3.2 -4.3 -2.7 -3.0 -3.1 -3.3\nType 2 Diabetes (T2D) (2012) 3.9 4.4 8.8 -2.0 -2.6 -2.5 -1.8 -2.5 -2.3 -2.1 -2.6 -2.6 -2.1 -2.6 -2.2 -2.2 -2.2 -2.5 -1.4 -2.6 -2.0 -1.4 -1.9 -2.0 -2.2 -1.7 -2.3 -1.4 -2.4 -1.6 -2.2 -1.7 -2.0 -2.0 -2.6 -1.4 -2.1 -2.5 -1.3 -1.1 -2.1 -1.5 -1.9 -2.4 -2.0 -2.0 -2.3 -2.0 -3.0 -2.1 -1.9 -2.2 -1.3 -2.1 -2.9 -1.2\nUlcerative Colitis 4.1 5.9 13.8 2.3 2.3 2.1 2.6 2.3 2.3 2.8 0.4 2.7 2.4 1.6 2.4 2.4 2.1 2.2 2.5 2.1 3.0 3.3 2.5 2.3 2.5 1.6 0.9 3.7 2.3 2.8 2.1 3.1 2.5 2.3 1.6 2.2 0.6 2.2 2.5 3.5 2.8 2.8 3.1 2.0 3.0 2.4 2.3 2.4 1.8 1.4 3.0 2.6 2.5 2.0 1.9 3.2\nBlood Eosinophil Count 0.7 5.7 20.8 -1.5 -2.5 -2.2 -1.9 -2.1 -1.8 -2.4 -1.6 -3.3 -1.4 -1.9 -2.0 -1.7 -1.2 -2.3 -2.3 -2.5 -2.7 -2.8 -3.3 -1.6 -1.9 -3.4 -0.3 -3.6 -2.1 -2.3 -1.5 -2.6 -2.3 -1.5 -1.1 -1.6 -0.2 -1.9 -1.6 -4.6 -3.1 -2.8 -3.6 -1.3 -2.5 -2.1 -1.6 -1.8 -2.6 -1.2 -2.4 -3.5 -2.7 -4.4 -1.9 -2.2\nBlood Platelet Count 0.1 1.0 6.2 1.1 1.1 0.6 1.3 0.7 1.1 1.2 2.5 -0.8 1.1 1.2 1.0 1.1 2.1 1.1 0.6 -1.3 0.8 1.5 0.5 1.2 0.5 2.0 0.7 -1.3 0.6 1.0 1.1 0.8 0.9 1.2 0.8 0.5 0.1 0.9 1.1 -0.4 0.2 -0.2 0.6 0.7 0.6 1.0 1.0 0.6 0.4 0.1 1.0 0.2 -0.7 0.5 -0.3 1.2\nBlood Red Count 2.7 26.1 42.1 -4.9 -5.8 -5.1 -5.0 -6.1 -5.9 -4.7 -4.8 -6.3 -4.8 -6.0 -5.2 -5.2 -5.9 -6.1 -4.3 -6.4 -5.0 -4.2 -5.0 -4.9 -5.8 -5.3 -6.0 -5.4 -6.0 -4.6 -5.6 -4.4 -4.8 -4.9 -6.5 -4.4 -5.2 -4.8 -4.7 -1.5 -5.2 -4.8 -3.7 -6.1 -4.4 -4.8 -5.3 -4.8 -5.3 -5.4 -4.7 -3.6 -3.1 -3.0 -6.1 -4.4\nBlood White Count 0.1 1.0 10.3 0.5 0.4 0.2 0.7 -0.0 -0.1 0.8 0.1 -2.1 0.7 0.5 0.7 0.7 1.4 0.2 0.2 -3.2 0.9 1.3 -0.1 0.8 -0.0 -0.6 -0.7 -1.1 -0.5 0.2 0.6 0.9 0.1 0.8 -0.7 -0.7 -1.8 0.3 -0.0 1.7 0.3 0.2 1.8 0.0 0.8 0.6 0.7 -0.5 0.6 -1.5 1.0 1.4 0.9 2.8 0.1 0.6\nHeel T-Score 0.3 2.5 7.0 1.7 1.9 1.3 1.7 1.6 2.1 1.4 2.3 1.0 1.5 1.6 1.5 1.6 1.6 1.5 2.0 2.5 1.3 1.0 1.4 1.6 1.6 1.7 2.3 0.1 1.8 1.6 1.6 0.7 1.6 1.5 2.2 1.9 2.6 1.8 1.3 0.6 1.1 1.1 0.4 1.8 1.3 1.5 1.6 2.3 1.2 2.5 1.4 0.4 0.7 -0.3 1.4 1.3\nBMI 1.8 10.6 24.3 -3.3 -3.4 -2.8 -2.7 -3.3 -2.6 -3.2 -2.5 -3.2 -3.7 -3.8 -3.9 -3.8 -3.3 -3.7 -3.1 -2.4 -4.2 -3.0 -2.5 -3.6 -3.4 -2.5 -3.2 -3.7 -2.6 -2.8 -3.6 -3.2 -3.1 -3.6 -3.2 -2.6 -2.0 -1.7 -2.3 -3.5 -3.5 -4.2 -3.9 -3.7 -3.6 -3.5 -3.6 -2.0 -3.7 -1.3 -3.8 -1.9 -4.7 -4.9 -2.4 -2.9\nHeight 0.1 2.7 20.5 1.3 -1.9 -0.3 0.2 0.0 -1.1 -0.5 -3.8 0.1 1.6 0.1 1.3 1.0 -3.2 -1.1 2.9 -0.3 1.8 -0.7 0.3 1.0 0.5 -3.7 0.9 1.3 0.2 0.9 0.6 0.3 0.7 1.0 -0.4 2.9 0.1 -0.4 1.4 4.5 0.6 3.1 1.5 0.9 2.0 0.6 0.7 1.3 1.2 1.6 1.1 0.0 2.8 1.6 -1.9 0.1\nWaist Hip Ratio (WHR) 3.8 16.9 31.5 -4.3 -4.3 -4.3 -2.9 -4.3 -5.0 -4.3 -4.9 -4.6 -4.1 -4.0 -3.8 -4.1 -4.6 -4.3 -4.3 -4.3 -3.3 -2.8 -5.1 -4.1 -4.4 -4.2 -4.7 -3.2 -4.7 -4.1 -4.1 -3.8 -4.5 -4.0 -4.5 -4.9 -5.6 -4.6 -4.8 -3.1 -4.0 -3.7 -3.0 -4.2 -3.8 -4.2 -4.0 -4.8 -3.3 -4.7 -3.5 -3.8 -2.2 -2.3 -3.0 -3.7\nSystolic Blood Pressure 1.8 9.1 36.1 -3.1 -1.8 -2.7 -2.5 -2.4 -3.2 -3.4 0.1 -3.2 -3.3 -2.2 -2.8 -2.8 -1.5 -2.5 -3.3 -2.3 -2.6 -3.3 -3.8 -2.7 -2.5 -1.4 -1.8 -2.5 -2.8 -3.8 -2.4 -4.0 -3.1 -2.8 -1.3 -3.7 -1.0 -4.0 -5.0 -5.0 -2.7 -2.2 -3.8 -2.5 -3.3 -3.1 -2.8 -4.3 -0.9 -2.5 -3.2 -6.0 0.2 -3.1 -1.3 -3.9\nSmoking Status 1.0 2.4 8.1 -1.7 -1.7 -1.4 -1.5 -1.4 -1.4 -1.5 -2.8 -1.7 -1.4 -1.4 -1.5 -1.5 -1.3 -1.7 -1.2 -1.3 -1.3 -1.3 -2.0 -1.6 -1.6 -1.7 -1.4 -1.8 -1.5 -1.7 -1.5 -1.4 -1.8 -1.6 -1.6 -1.9 -1.9 -1.5 -1.5 -1.5 -1.5 -1.4 -1.3 -1.4 -1.5 -1.8 -1.4 -1.9 -1.3 -1.2 -1.4 -1.4 0.0 -1.5 -0.6 -1.5\nAllergy or Eczema 1.2 3.2 23.3 -1.4 -1.5 -1.0 -2.2 -1.0 -0.3 -1.7 0.4 -0.5 -1.6 -1.1 -1.7 -1.5 0.1 -0.8 -1.7 -0.3 -2.5 -3.1 -1.8 -1.4 -1.2 -1.3 0.8 -3.1 -0.9 -2.0 -1.1 -2.2 -1.7 -1.5 -0.1 -1.3 0.7 -1.1 -1.4 -4.8 -1.8 -1.7 -3.2 -0.8 -2.2 -1.7 -1.3 -1.8 -1.2 0.5 -2.6 -2.2 -0.9 -3.3 0.1 -2.8\nCardiovascular Disease 3.2 10.7 32.1 -3.0 -2.3 -3.2 -2.3 -2.7 -3.0 -3.1 -1.1 -2.8 -2.9 -3.1 -3.0 -2.8 -2.1 -2.8 -4.0 -3.2 -3.2 -2.9 -4.3 -2.6 -3.0 -3.0 -3.1 -3.2 -3.3 -3.4 -2.4 -3.6 -3.8 -2.7 -2.2 -4.5 -3.5 -3.5 -4.5 -5.7 -3.6 -3.6 -3.5 -2.9 -3.2 -3.3 -2.7 -4.6 -2.5 -3.7 -3.3 -4.3 -1.9 -3.7 -1.8 -3.8\nHypothyroidism (self reported) 3.0 6.8 12.0 -3.0 -2.9 -2.5 -2.4 -2.5 -2.7 -3.0 -2.7 -2.7 -2.8 -2.4 -2.8 -2.8 -2.6 -2.6 -2.0 -2.0 -2.5 -2.6 -3.4 -2.9 -2.5 -3.3 -1.6 -3.2 -2.7 -2.6 -2.5 -3.0 -2.5 -3.0 -2.1 -2.2 -1.4 -2.9 -2.9 -2.9 -2.3 -2.1 -2.9 -2.3 -2.8 -2.8 -2.7 -2.4 -1.8 -1.3 -2.9 -3.5 -1.8 -3.3 -1.2 -2.5\nRespiratory disease 0.9 2.0 11.6 -1.3 -1.4 -1.0 -1.3 -1.1 -0.8 -1.2 -0.1 -0.7 -1.2 -1.5 -1.5 -1.3 -0.6 -1.1 -1.7 -0.6 -2.0 -1.6 -1.8 -1.3 -1.0 -1.3 -0.7 -1.4 -1.1 -1.5 -1.3 -1.2 -1.6 -1.3 -0.7 -1.8 -0.7 -1.1 -1.3 -3.4 -1.3 -1.6 -2.1 -1.0 -1.8 -1.5 -1.1 -1.7 -1.8 -1.1 -1.7 -1.5 -0.7 -2.5 -0.3 -1.4\nType 2 Diabetes (T2D) (2018) 6.9 13.0 27.1 -3.6 -3.4 -3.6 -1.8 -3.6 -3.9 -3.3 -3.7 -3.4 -3.3 -3.7 -3.6 -3.4 -4.4 -3.8 -3.8 -3.5 -3.7 -1.9 -4.0 -3.2 -3.8 -3.5 -4.5 -3.2 -4.0 -2.9 -3.4 -3.1 -4.0 -3.3 -4.0 -4.5 -5.2 -3.4 -4.0 -4.1 -3.7 -4.3 -2.8 -3.6 -3.4 -3.7 -3.4 -4.2 -3.8 -4.5 -3.1 -3.0 -3.2 -3.2 -3.0 -2.4\nLung FEV1/FVC ratio 23.6 119.5 158.8 -10.8 -11.8 -11.4 -10.5 -11.6 -12.6 -11.3 -9.2 -11.3 -10.6 -11.4 -11.2 -10.9 -12.2 -12.5 -10.5 -11.4 -11.3 -10.0 -11.1 -10.5 -11.7 -11.7 -11.4 -10.2 -11.6 -10.9 -11.1 -10.9 -10.6 -10.6 -11.7 -9.6 -10.8 -10.9 -10.4 -9.3 -11.6 -11.6 -10.5 -11.6 -10.7 -10.8 -11.1 -10.3 -10.5 -9.9 -10.5 -10.2 -10.2 -10.2 -11.2 -9.6\nLung FVC 0.4 2.0 12.2 0.9 2.1 1.6 0.7 1.2 2.0 1.5 3.5 1.0 0.7 0.6 0.4 0.7 1.9 1.7 1.7 1.7 0.5 0.9 2.1 0.7 1.5 1.8 0.4 0.8 1.9 1.5 0.7 1.2 1.4 0.7 1.8 1.1 2.6 2.0 1.0 0.2 1.7 1.1 0.6 0.7 0.8 1.2 0.9 1.0 1.5 2.3 0.4 1.0 1.6 0.5 1.3 0.4\nNeuroticism 0.8 2.0 4.9 -2.0 -1.3 -1.1 -1.7 -1.5 -0.6 -1.0 -0.2 -0.9 -2.0 -2.0 -2.0 -2.0 -0.3 -0.9 -1.4 -1.1 -1.8 -0.8 -1.1 -2.2 -1.1 -1.4 -1.7 -1.1 -1.4 -1.2 -2.2 -0.8 -1.3 -2.1 -1.6 -1.5 -0.9 -1.2 -1.3 -0.8 -0.6 -1.0 -1.1 -1.9 -1.6 -1.6 -1.9 -1.4 -1.8 -1.2 -1.6 0.1 -0.7 -1.2 -0.2 -1.3\nChronotype (morning person) 0.6 1.3 3.4 1.0 1.6 1.2 1.1 1.1 1.3 1.3 1.4 1.0 0.8 1.0 0.9 1.0 1.1 1.2 0.8 1.0 1.0 1.3 1.7 1.1 0.8 1.5 0.4 1.5 1.2 1.3 0.7 1.2 1.0 1.0 0.9 0.6 0.8 1.3 0.9 1.3 1.4 1.3 1.3 0.8 1.1 1.1 0.9 1.1 1.1 0.8 1.1 1.6 1.8 1.7 1.1 1.0\nHair Pigment 0.1 2.7 7.2 1.5 1.6 1.8 2.4 1.5 1.7 2.1 -0.5 1.3 1.8 0.9 1.5 1.5 0.6 1.2 1.4 1.8 1.7 2.7 1.3 1.5 1.8 0.8 0.4 2.0 1.3 2.2 1.0 2.4 1.5 1.5 0.7 0.4 -0.2 1.7 1.5 2.2 1.8 1.6 2.6 1.1 2.3 1.5 1.7 1.3 0.8 0.2 2.2 2.5 1.8 1.0 1.7 2.1\nTanning 0.0 0.1 0.8 -0.2 -0.0 -0.4 -0.2 -0.4 -0.2 -0.0 0.5 -0.3 -0.5 -0.1 -0.2 -0.3 -0.2 0.1 0.2 -0.5 -0.1 0.0 0.1 -0.2 -0.2 0.3 -0.9 -0.4 -0.3 0.0 -0.2 -0.5 -0.0 -0.3 0.0 0.2 -0.1 -0.2 -0.1 0.4 -0.1 -0.0 -0.1 -0.3 -0.3 -0.2 -0.4 0.2 -0.0 -0.1 -0.3 0.1 -0.5 0.6 -0.5 -0.2\nHand grip strength (left) 0.2 0.6 2.4 -0.5 -1.1 -1.1 -1.0 -1.0 -1.1 -0.9 -1.1 -0.7 -0.6 -0.7 -0.7 -0.7 -0.7 -0.9 -0.4 -1.1 -0.6 -1.1 -0.3 -0.7 -0.9 -0.4 -0.7 -0.5 -0.8 -0.6 -0.8 -0.8 -0.6 -0.6 -0.9 0.1 -0.2 -0.9 -0.4 0.6 -0.6 0.2 -0.7 -0.8 -0.5 -0.6 -0.8 -0.5 -0.8 -0.6 -0.7 -1.1 1.2 -0.4 -1.5 -0.9\nNumber of treatments/medications taken 2.3 4.1 14.5 -2.1 -1.6 -1.2 -1.4 -1.4 -1.6 -1.9 -1.6 -1.7 -1.9 -1.6 -1.8 -1.7 -1.7 -1.6 -1.7 -1.2 -2.1 -1.8 -3.0 -1.7 -1.6 -2.5 -1.5 -3.0 -1.8 -2.4 -1.5 -1.9 -2.5 -1.8 -1.5 -3.4 -2.6 -1.7 -3.1 -3.8 -1.9 -2.3 -1.8 -1.6 -1.9 -2.3 -1.5 -2.9 -1.3 -1.7 -2.1 -1.5 -1.3 -2.0 0.5 -2.4\nAverage weekly spirits intake 0.7 0.9 4.3 -0.9 -0.9 -1.0 0.0 -1.1 -0.9 -0.6 -1.9 -1.1 -0.6 -1.1 -0.9 -0.8 -1.8 -1.2 -0.9 -0.8 -0.8 0.2 -0.6 -0.7 -0.9 -0.7 -1.9 0.0 -0.8 -0.2 -1.3 -0.4 -0.9 -0.8 -1.3 -1.1 -2.1 -0.6 -0.7 -0.3 -0.7 -1.0 -0.1 -1.0 -0.5 -0.9 -0.8 -1.0 -1.3 -1.2 -0.3 0.0 -0.2 -0.8 -0.8 -0.1\nSensitivity / hurt feelings 1.5 2.6 6.7 -2.1 -1.0 -1.3 -1.3 -1.4 -1.4 -1.4 0.4 -1.2 -1.8 -1.9 -1.9 -1.9 -1.1 -1.3 -2.2 -1.4 -1.8 -0.9 -1.7 -2.0 -1.4 -1.5 -2.3 -1.3 -1.6 -1.5 -2.0 -1.4 -1.8 -1.9 -1.5 -2.6 -1.7 -1.8 -2.2 -2.0 -1.2 -1.6 -1.2 -1.7 -1.7 -1.8 -1.7 -2.1 -1.3 -2.1 -1.6 -1.0 -0.6 -0.7 -0.4 -1.5\nFrequency of depressed mood in last 2 weeks 4.8 6.8 10.0 -2.8 -2.6 -2.6 -2.6 -2.8 -2.4 -2.4 -1.8 -2.5 -2.8 -3.0 -2.8 -2.8 -2.0 -2.4 -2.5 -2.4 -3.0 -2.3 -2.9 -2.7 -2.5 -2.7 -2.6 -2.5 -2.8 -2.5 -3.0 -2.4 -2.8 -2.8 -2.8 -2.8 -2.7 -2.8 -2.9 -2.2 -2.6 -2.6 -2.3 -3.0 -2.7 -2.8 -2.8 -2.9 -3.2 -2.5 -2.7 -1.4 -1.7 -1.8 -2.4 -2.7\nHearing difficulty/problems: Yes 0.4 0.5 2.1 0.8 1.3 0.7 -0.2 0.9 1.4 1.0 0.8 0.7 0.7 0.5 1.0 0.8 0.6 0.9 0.7 0.8 0.6 -0.1 0.8 1.0 1.0 0.9 1.0 0.3 1.0 0.1 1.1 0.6 0.5 0.9 0.8 0.3 0.8 0.3 0.3 0.8 0.6 1.0 0.5 0.7 0.8 0.7 0.8 0.5 -0.1 0.6 0.5 0.8 0.3 0.5 0.6 0.3\nRelative age of first facial hair 0.1 0.1 2.4 0.2 -0.4 -0.2 -0.2 -0.2 -0.3 -0.0 0.3 -0.6 0.3 -0.3 0.1 0.1 -0.3 -0.6 0.3 -0.4 0.2 -0.4 -0.1 0.1 0.1 -0.3 0.5 -0.0 -0.3 -0.1 0.2 -0.3 0.2 0.2 -0.1 0.7 0.5 -0.4 0.1 0.3 -0.0 0.5 -0.2 0.1 0.3 0.2 0.1 0.3 0.4 0.0 0.0 -1.6 0.3 -0.3 -0.6 0.1\nOther serious medical condition/disability diagnosed by doctor 0.8 1.0 4.2 -1.3 -0.5 -0.8 -0.4 -0.8 -0.6 -0.8 -1.1 -1.3 -1.1 -0.9 -0.8 -1.1 -0.4 -0.6 -0.5 -0.6 -0.7 -0.3 -1.5 -1.1 -0.7 -0.8 -1.3 -1.5 -0.9 -0.7 -1.1 -0.9 -1.3 -1.2 -1.0 -1.9 -1.5 -1.1 -2.1 -0.6 -0.7 -0.8 -0.2 -1.1 -0.8 -1.3 -1.0 -1.6 -0.8 -0.9 -1.0 -0.3 -0.2 -0.1 0.1 -1.2\nEver used hormone-replacement therapy (HRT) 1.5 1.9 6.0 -1.1 -1.0 -1.3 -1.4 -1.2 -1.5 -1.3 -0.1 -0.6 -1.3 -1.4 -1.4 -1.2 -0.7 -1.2 -1.7 -1.5 -1.8 -1.5 -1.3 -1.0 -1.3 -1.8 -1.2 -1.3 -1.3 -1.7 -1.0 -1.5 -1.6 -1.0 -1.2 -1.6 -1.4 -1.5 -1.6 -2.4 -1.6 -1.8 -1.7 -1.1 -1.5 -1.3 -1.2 -1.6 -1.4 -1.7 -1.4 -1.1 -1.3 -0.9 -1.1 -1.5\nEver had hysterectomy (womb removed) 0.3 0.3 2.2 -0.4 -0.5 -0.4 -0.5 -0.5 -0.8 -0.1 0.1 -0.2 -0.3 -0.6 -0.5 -0.3 -0.6 -0.2 -1.1 -1.0 -0.4 0.0 -0.5 -0.3 -0.4 -0.8 -1.1 0.3 -0.8 -0.4 -0.4 0.2 -0.4 -0.3 -0.7 -0.7 -1.5 -0.4 -0.2 -0.5 -0.1 -0.3 -0.0 -0.4 -0.3 -0.4 -0.4 -0.7 -0.5 -1.1 -0.1 0.3 0.2 0.5 -0.4 0.0\nSystolic blood pressure, automated reading 2.3 6.8 17.8 -2.9 -2.0 -2.3 -2.3 -2.3 -2.6 -3.1 -0.1 -3.0 -3.1 -2.0 -2.8 -2.8 -1.4 -2.3 -2.7 -1.7 -2.6 -3.1 -2.9 -2.8 -2.4 -1.6 -1.2 -2.5 -2.3 -3.2 -2.5 -3.5 -2.7 -2.8 -1.4 -2.7 -0.7 -3.1 -3.7 -3.9 -2.4 -1.9 -3.5 -2.3 -3.0 -2.9 -2.7 -2.9 -1.1 -1.4 -3.0 -4.2 -0.2 -2.8 -1.0 -3.5\nEye problems/disorders: Diabetes related eye disease 1.1 1.3 2.9 -1.0 -1.5 -1.1 -1.3 -1.0 -1.4 -1.4 -1.1 -0.4 -1.0 -0.9 -0.8 -0.9 -1.1 -0.8 -1.4 -1.6 -1.0 -1.5 -1.2 -0.9 -1.1 -0.4 -0.3 -1.0 -1.4 -1.4 -1.1 -1.2 -1.3 -0.9 -1.1 -1.2 -1.4 -1.3 -1.1 -1.2 -1.0 -0.9 -1.0 -0.8 -1.2 -1.1 -0.9 -1.7 -0.9 -1.5 -1.1 -1.0 0.4 -0.6 -1.1 -1.3\nAngina 0.5 0.7 4.9 -0.3 -0.8 -1.0 -0.8 -0.5 -0.2 -0.9 0.4 -0.7 -0.7 -0.3 -0.5 -0.4 -0.5 -0.3 -0.4 -0.6 -0.9 -1.1 -1.0 -0.2 -0.8 -0.4 0.6 -2.2 -0.6 -0.6 -0.4 -1.2 -0.9 -0.4 -0.2 -0.1 -0.4 -0.1 -0.0 -1.6 -1.1 -1.0 -1.6 -0.2 -1.0 -0.7 -0.5 -0.2 -1.1 0.4 -1.0 -0.5 -1.6 -1.5 -0.6 -0.9\nMedication for hormone replacement therapy 0.1 0.1 1.0 0.0 -0.4 -0.4 -0.7 -0.3 -0.3 -0.0 0.7 0.2 0.2 -0.6 -0.3 -0.1 -0.3 -0.2 0.1 -0.7 -0.3 -0.4 0.3 0.0 -0.1 -0.7 -0.4 -0.3 -0.2 -0.1 -0.2 0.1 0.0 0.0 -0.4 0.5 -0.1 -0.4 0.1 -0.0 -0.3 -0.1 -0.2 -0.3 0.2 0.0 -0.1 -0.2 -0.6 -0.1 -0.1 0.2 0.3 0.1 -1.0 -0.4\nVitamin and mineral supplements 0.1 0.2 2.3 -0.3 0.1 -0.0 0.1 -0.2 0.4 0.1 0.9 -0.7 -0.3 -0.2 -0.5 -0.3 0.4 -0.0 -0.4 0.2 -0.5 0.1 0.2 -0.4 -0.1 0.4 0.4 -0.9 -0.0 0.3 -0.5 -0.3 0.1 -0.5 0.1 0.2 0.7 0.1 0.3 -0.3 -0.1 -0.4 -0.5 -0.2 -0.6 -0.2 -0.3 0.6 -0.1 0.5 -0.4 0.2 -1.5 -0.2 0.1 -0.2\nSupplements: Zinc 0.9 0.9 4.0 -0.8 -0.9 -0.6 -0.9 -0.8 -1.3 -0.8 -0.8 -0.4 -0.5 -0.8 -0.7 -0.7 -1.1 -0.9 -1.3 -1.3 -0.6 -0.7 -1.0 -0.6 -0.9 -0.8 -1.4 -0.6 -1.1 -1.1 -1.0 -0.7 -1.1 -0.7 -1.1 -1.6 -1.6 -0.9 -1.5 -1.0 -0.9 -1.2 -0.3 -1.0 -0.4 -0.7 -0.7 -1.6 -0.4 -2.0 -0.6 -0.8 0.3 -0.2 -0.7 -0.8\nMedication: Co-codamol 3.3 3.8 7.4 -1.7 -1.6 -1.8 -2.3 -1.8 -1.5 -1.6 -2.0 -1.9 -1.9 -2.1 -1.9 -1.8 -1.3 -1.7 -2.0 -2.3 -2.2 -2.0 -1.9 -1.6 -2.1 -1.8 -2.7 -2.0 -1.8 -2.3 -1.5 -1.6 -2.2 -1.6 -2.0 -2.6 -2.6 -1.6 -1.9 -2.3 -2.0 -2.2 -1.8 -1.9 -1.9 -2.0 -1.8 -2.4 -2.3 -2.1 -2.0 -1.1 -1.5 -1.7 -1.5 -1.8\nMedication: Metformin 10.1 14.3 23.4 -4.3 -3.7 -3.7 -2.3 -3.9 -3.8 -3.7 -3.9 -4.0 -4.2 -4.0 -4.2 -4.1 -3.5 -3.7 -3.6 -3.2 -3.9 -2.3 -4.2 -4.0 -4.0 -3.7 -4.5 -3.7 -4.1 -3.4 -4.1 -3.4 -4.2 -4.2 -4.0 -4.6 -4.8 -3.3 -4.0 -3.9 -3.3 -3.8 -3.2 -4.0 -4.1 -4.1 -4.1 -4.0 -3.6 -3.8 -3.8 -2.9 -2.8 -3.4 -2.2 -3.0\nDiabetes (father) 5.6 6.9 12.1 -2.3 -3.0 -2.8 -2.8 -2.5 -2.9 -2.7 -2.7 -2.4 -2.1 -2.6 -2.4 -2.3 -2.7 -3.1 -2.1 -2.3 -2.5 -2.9 -3.1 -2.2 -2.5 -3.1 -2.4 -2.6 -2.6 -2.9 -2.1 -2.7 -2.7 -2.2 -2.4 -2.3 -2.4 -2.8 -2.7 -2.6 -3.2 -2.6 -2.9 -2.4 -2.3 -2.7 -2.3 -2.5 -2.9 -2.4 -2.4 -3.2 -2.4 -3.5 -2.9 -2.3\nDiabetes (mother) 6.2 8.0 14.3 -2.9 -3.1 -3.1 -2.2 -3.0 -3.2 -2.9 -2.2 -3.4 -2.7 -3.1 -2.9 -2.8 -2.8 -3.1 -2.5 -2.7 -2.8 -2.0 -3.3 -2.8 -2.7 -3.8 -3.5 -2.1 -3.1 -2.5 -2.8 -2.5 -2.9 -2.8 -3.0 -2.7 -3.1 -3.3 -2.8 -2.3 -2.8 -2.5 -2.3 -2.9 -2.6 -2.9 -2.9 -3.1 -3.0 -3.1 -2.7 -2.8 -2.1 -2.4 -2.6 -2.3\nSevere depression (siblings) 0.2 0.2 1.7 0.1 0.4 0.2 -0.1 0.2 0.7 0.5 -0.1 0.1 0.3 -0.3 0.1 0.1 0.7 0.3 0.3 -0.0 0.2 0.3 0.5 0.1 0.4 0.1 -0.3 1.0 0.4 0.2 -0.3 0.6 0.1 0.1 -0.0 -0.2 -0.3 0.1 0.2 0.9 0.3 0.6 0.5 0.1 0.5 0.2 0.2 0.1 -0.5 -0.1 0.3 1.0 1.3 0.5 0.7 0.1\nPack years adult smoking proportion 3.7 5.6 9.5 -2.5 -2.6 -2.4 -2.2 -2.5 -2.6 -3.0 -1.6 -2.1 -2.4 -2.1 -2.6 -2.6 -1.5 -2.4 -2.2 -2.2 -2.7 -2.8 -2.4 -2.6 -2.6 -1.2 -1.6 -2.7 -2.3 -2.6 -2.3 -3.1 -2.6 -2.5 -1.9 -1.9 -1.1 -2.2 -2.5 -2.6 -2.7 -2.6 -2.8 -2.2 -2.8 -2.6 -2.5 -2.0 -1.9 -1.2 -2.8 -2.7 -1.7 -1.9 -2.2 -2.8\nImpedance of leg (right) 0.3 1.5 8.5 -0.3 -1.2 -1.2 -0.7 -1.2 -1.9 -0.6 0.7 -1.6 -0.3 -0.7 -0.5 -0.1 -0.9 -1.1 -1.4 -2.6 -0.7 -0.5 -1.7 0.1 -1.1 -1.5 -0.7 -0.7 -1.8 -1.2 0.2 -0.6 -0.7 0.0 -0.9 -0.7 -1.9 -1.7 -1.0 -2.1 -1.6 -1.6 -0.9 -0.6 -0.7 -0.3 -0.4 -1.7 -1.0 -2.9 -0.3 -2.3 -1.2 -0.4 -1.9 -0.2\nLeg fat-free mass (left) 0.4 2.0 7.4 -1.5 -1.8 -1.2 -1.6 -1.4 -1.2 -1.8 -2.7 -1.0 -1.6 -1.8 -1.7 -1.9 -2.0 -1.9 -0.6 -0.5 -1.5 -1.9 -0.3 -2.0 -1.6 -1.5 -1.4 -1.3 -0.7 -1.1 -2.1 -1.6 -1.2 -1.9 -1.6 -0.4 -0.3 -0.7 -0.8 0.4 -1.1 -0.6 -1.4 -1.6 -1.2 -1.7 -1.8 -0.2 -1.0 1.0 -1.9 -0.5 -0.5 -1.5 -1.2 -1.7\nTrunk fat percentage 3.2 12.9 24.7 -3.7 -3.8 -3.3 -3.2 -3.6 -3.1 -3.6 -2.5 -3.9 -4.0 -3.8 -4.1 -3.9 -3.1 -4.1 -3.5 -3.1 -4.2 -3.4 -3.4 -3.8 -3.9 -2.8 -3.3 -3.6 -3.1 -3.6 -3.8 -3.6 -3.5 -3.8 -3.2 -3.0 -2.5 -2.9 -2.9 -4.4 -4.2 -4.2 -4.5 -3.7 -3.9 -3.8 -3.8 -2.8 -3.9 -2.0 -4.1 -3.3 -4.2 -5.0 -2.4 -3.5\nHand grip strength (right) 0.9 2.3 4.3 -1.5 -2.1 -1.9 -1.7 -1.8 -1.9 -1.8 -2.0 -1.5 -1.6 -1.7 -1.5 -1.6 -1.8 -1.9 -0.9 -1.7 -1.2 -1.6 -1.4 -1.6 -1.8 -1.1 -1.7 -1.3 -1.6 -1.4 -1.9 -1.6 -1.6 -1.6 -1.9 -0.9 -1.4 -1.8 -1.3 0.2 -1.2 -0.4 -1.3 -1.8 -1.3 -1.6 -1.7 -1.3 -1.4 -1.1 -1.4 -1.5 0.3 -1.0 -1.8 -1.6\nTownsend deprivation index at recruitment 4.0 5.6 12.7 -2.6 -1.7 -2.1 -1.4 -2.1 -1.8 -2.0 -2.0 -2.5 -2.3 -2.6 -2.6 -2.5 -1.9 -2.4 -2.6 -2.2 -2.7 -1.3 -2.3 -2.5 -2.5 -1.4 -3.1 -2.6 -2.3 -2.0 -2.7 -2.1 -2.8 -2.4 -2.4 -3.6 -2.8 -2.1 -2.8 -3.3 -2.2 -2.9 -2.0 -2.4 -2.5 -2.6 -2.3 -2.9 -2.4 -2.8 -2.3 -2.2 -1.4 -2.5 -1.3 -1.7\nCurrent tobacco smoking 1.1 1.8 4.0 -1.2 -1.4 -1.5 -1.2 -1.2 -1.5 -1.6 -1.5 -1.0 -0.9 -1.1 -1.1 -1.1 -1.3 -1.4 -1.1 -1.4 -1.1 -1.2 -1.7 -1.2 -1.4 -1.0 -1.3 -1.0 -1.4 -1.5 -1.1 -1.5 -1.6 -1.1 -1.3 -1.7 -1.9 -1.8 -1.7 -1.7 -1.2 -1.2 -1.1 -1.0 -1.3 -1.5 -1.1 -2.0 -1.0 -1.5 -1.0 -1.8 0.2 -0.7 -1.4 -1.2\nAverage weekly fortified wine intake 3.1 3.6 8.0 1.5 1.9 2.4 2.4 2.1 2.1 1.7 0.7 2.1 2.1 2.2 1.8 1.9 2.1 2.2 1.4 2.4 2.0 2.1 1.6 1.7 2.1 1.3 2.3 1.9 2.1 2.1 1.9 2.0 1.7 1.6 2.0 1.1 1.6 2.1 1.6 0.8 1.7 1.5 2.1 2.1 1.9 1.6 2.0 1.8 2.2 1.8 1.8 2.0 1.4 1.6 2.8 1.6\nMaternal smoking around birth 0.8 1.2 3.1 1.1 1.0 1.0 1.8 1.1 1.0 1.2 0.3 0.6 1.4 0.9 1.2 1.2 0.9 0.9 0.9 1.1 1.2 1.7 0.7 1.2 1.2 0.9 0.5 1.2 0.9 1.5 0.8 1.3 1.0 1.1 0.9 0.6 0.0 1.0 1.2 0.8 1.1 1.0 1.4 1.3 1.3 1.0 1.3 1.2 0.7 0.4 1.5 1.2 0.6 0.8 1.1 1.7\nFed-up feelings 0.9 1.7 4.2 -1.5 -1.3 -1.3 -0.9 -1.2 -0.9 -1.0 0.6 -0.7 -1.0 -1.5 -1.5 -1.3 -0.5 -0.8 -1.4 -1.5 -1.6 -0.6 -1.4 -1.3 -1.2 -0.7 -1.8 -1.6 -1.5 -0.9 -1.3 -0.8 -1.5 -1.3 -1.3 -1.8 -1.7 -1.1 -1.3 -1.8 -1.5 -1.7 -1.0 -1.3 -1.3 -1.4 -1.2 -1.5 -2.0 -2.0 -1.2 -0.6 -1.0 -0.9 -1.0 -1.0\nFrequency of unenthusiasm / disinterest in last 2 weeks 1.6 2.1 3.8 -1.7 -1.5 -1.6 -1.1 -1.7 -1.7 -1.5 -0.0 -1.4 -1.5 -1.9 -1.6 -1.7 -1.1 -1.4 -1.6 -1.3 -1.5 -0.8 -1.6 -1.7 -1.3 -1.2 -1.4 -1.2 -1.8 -1.1 -2.0 -1.4 -1.3 -1.7 -1.8 -1.2 -1.4 -1.5 -1.6 -0.8 -1.3 -1.5 -1.1 -1.8 -1.5 -1.5 -1.7 -1.2 -1.5 -1.6 -1.4 -1.1 -1.9 -0.8 -1.6 -1.2\nRelative age voice broke 0.9 1.4 3.1 -1.0 -1.2 -1.2 -1.2 -1.1 -1.1 -1.2 -1.7 -1.6 -1.0 -1.2 -1.0 -1.1 -1.4 -1.6 -0.1 -1.2 -1.2 -1.6 -1.4 -1.0 -1.1 -1.7 -1.0 -1.8 -1.1 -1.4 -0.9 -1.5 -1.3 -1.0 -1.0 -1.0 -0.7 -1.3 -1.3 -1.2 -1.0 -0.7 -1.3 -0.9 -1.2 -1.2 -1.0 -1.1 -0.5 -0.4 -1.3 -1.7 -0.7 -0.9 -0.9 -1.3\nTaking other prescription medications 0.9 1.4 6.3 -1.6 -0.7 -0.2 -0.2 -0.7 -0.4 -0.9 -0.4 -0.9 -1.4 -1.0 -1.4 -1.4 -0.3 -0.8 -1.3 -0.2 -1.2 -0.3 -1.5 -1.5 -0.6 -1.5 -0.8 -1.4 -0.8 -1.0 -1.4 -0.7 -1.3 -1.5 -0.7 -2.4 -1.1 -0.7 -1.8 -2.5 -0.8 -1.0 -0.9 -1.1 -1.2 -1.4 -1.0 -1.6 -0.4 -0.8 -1.4 -0.7 -0.0 -1.2 1.6 -1.6\nAge when periods started (menarche) 1.2 2.9 12.1 -1.7 -2.0 -1.9 -1.3 -1.8 -2.1 -1.7 -3.5 -1.6 -1.3 -1.6 -1.4 -1.4 -1.7 -1.8 -1.6 -2.4 -0.8 -1.0 -1.6 -1.5 -2.0 -1.8 -2.0 -0.6 -1.9 -1.5 -1.5 -1.2 -1.8 -1.6 -2.1 -1.7 -2.7 -2.3 -1.4 -0.1 -1.7 -0.3 -0.7 -1.5 -1.1 -1.7 -1.5 -2.1 -1.6 -2.2 -1.2 -1.7 2.2 -0.2 -1.5 -1.6\nBilateral oophorectomy (both ovaries removed) 2.3 2.7 5.9 -1.6 -1.7 -1.6 -1.6 -1.6 -2.1 -1.5 -2.3 -1.5 -1.5 -1.7 -1.6 -1.6 -2.0 -1.7 -1.9 -1.8 -1.5 -1.3 -1.4 -1.5 -1.9 -1.9 -2.4 -1.0 -1.8 -1.6 -1.7 -1.2 -1.8 -1.5 -2.1 -1.9 -2.4 -1.4 -1.5 -0.9 -1.5 -1.6 -1.0 -1.7 -1.4 -1.6 -1.6 -1.7 -1.4 -2.1 -1.5 -1.0 -0.6 -0.6 -1.6 -1.1\nHeel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 3.7 0.8 1.2 0.9 1.2 1.0 1.2 0.8 1.5 0.6 1.0 1.0 0.9 0.9 1.4 1.0 0.8 1.3 0.8 0.8 0.7 0.7 1.0 1.3 1.2 0.2 1.2 1.0 0.8 0.5 1.0 0.7 1.5 1.1 1.9 1.0 0.9 0.5 0.7 0.6 0.4 1.1 0.6 0.8 0.9 1.2 0.9 1.3 0.8 0.2 0.3 0.1 1.0 0.6\nTinnitus: Yes, but not now, but have in the past 0.2 0.2 1.2 -0.4 -0.2 0.1 -0.1 -0.2 -0.4 0.1 0.6 -0.2 -0.3 -0.5 -0.4 -0.3 -0.3 -0.2 -0.7 -0.4 -0.3 0.4 -0.4 -0.3 -0.3 -0.6 -1.0 0.2 -0.6 -0.1 -0.3 0.2 -0.2 -0.3 -0.4 -0.8 -0.7 -0.3 -0.4 -0.4 -0.3 -0.3 0.2 -0.5 -0.2 -0.1 -0.2 -0.5 -0.2 -1.1 -0.2 -0.3 0.1 0.3 0.1 0.1\nQualifications: CSEs or equivalent 0.3 0.4 3.2 -0.2 -0.3 -0.8 -0.1 -0.3 -0.8 -0.2 -0.5 -0.1 0.1 -0.5 -0.0 -0.1 -0.9 -0.4 -0.9 -0.7 -0.1 0.1 -0.6 -0.1 -0.2 -0.2 -1.7 0.8 -0.7 -0.3 -0.4 -0.1 -0.7 -0.0 -0.5 -1.1 -1.6 -1.0 -0.4 -0.2 -0.3 -0.2 0.2 -0.3 -0.2 -0.4 -0.2 -1.2 -0.5 -1.8 0.2 -0.3 0.5 0.3 -0.8 -0.3\nSerious illness, injury or assault to yourself 1.4 1.7 6.1 -1.3 -1.3 -1.1 -0.7 -1.0 -1.1 -1.1 -1.9 -0.7 -1.0 -1.3 -1.0 -1.0 -1.4 -1.2 -1.4 -1.5 -1.0 -0.7 -1.8 -1.0 -1.2 -1.3 -1.2 -1.3 -1.5 -1.3 -1.1 -0.9 -1.7 -1.1 -1.5 -2.2 -2.5 -1.4 -2.0 -1.4 -1.7 -1.4 -0.6 -1.2 -0.8 -1.4 -1.0 -1.6 -1.5 -2.0 -1.0 -0.9 -0.6 -0.6 -0.5 -1.1\nHigh blood pressure 3.8 10.7 25.9 -3.5 -2.5 -3.0 -2.5 -2.9 -2.8 -3.1 -1.6 -2.9 -3.6 -3.2 -3.4 -3.2 -2.3 -2.9 -3.6 -3.0 -3.3 -2.8 -4.1 -3.2 -3.2 -3.1 -3.2 -3.4 -3.3 -3.5 -2.9 -3.5 -3.8 -3.3 -2.5 -4.5 -3.5 -3.5 -4.4 -5.1 -3.1 -3.1 -3.5 -3.2 -3.5 -3.6 -3.1 -4.4 -2.2 -2.9 -3.5 -3.6 -1.3 -3.2 -1.1 -4.0\nHayfever, allergic rhinitis or eczema 1.2 2.6 14.2 -0.9 -1.6 -1.0 -2.4 -1.0 -0.5 -1.6 0.2 -0.2 -1.5 -1.0 -1.3 -1.2 -0.2 -0.9 -1.4 -0.4 -2.3 -3.4 -1.8 -0.9 -1.0 -1.7 0.8 -2.8 -1.0 -2.1 -0.7 -2.1 -1.7 -1.1 -0.2 -1.1 0.7 -1.2 -1.2 -3.8 -1.6 -1.5 -2.9 -0.7 -2.0 -1.5 -1.1 -1.7 -1.2 0.3 -2.4 -1.7 -1.1 -2.6 -0.6 -2.7\nMultivitamins +/- minerals 0.2 0.3 3.3 -0.0 -0.8 -0.2 -0.6 -0.3 -0.7 -0.4 -1.8 0.3 0.1 -0.3 -0.0 -0.1 -0.9 -0.8 -0.3 -0.6 -0.3 -0.7 -0.7 -0.0 -0.3 -1.1 -0.5 0.2 -0.4 -0.7 0.1 0.0 -0.5 0.1 -0.7 -0.5 -0.9 -0.3 -0.4 -0.3 -0.5 -0.5 -0.1 -0.2 0.2 -0.2 -0.0 -0.6 -0.7 -0.7 -0.1 -0.2 -0.0 -0.5 -0.6 0.1\nStomach or abdominal pain in last month 0.6 0.8 2.9 -0.8 -0.5 -0.7 -0.9 -0.9 -1.0 -0.3 0.2 -0.3 -0.4 -1.2 -0.8 -0.7 -1.0 -0.9 -1.4 -1.1 -1.0 -0.5 -0.6 -0.6 -0.9 -1.0 -1.6 0.0 -0.7 -0.7 -0.8 -0.3 -0.8 -0.7 -1.1 -1.2 -1.7 -0.9 -1.0 -0.9 -1.0 -1.2 -0.3 -1.0 -0.6 -0.7 -0.7 -1.0 -1.1 -1.4 -0.6 -0.2 -1.3 0.0 -0.8 -0.6\nSupplements: Glucosamine 0.9 1.2 3.9 1.1 1.1 1.0 0.6 0.9 0.7 1.2 0.6 1.2 1.4 0.8 1.1 1.2 0.6 1.1 1.2 0.4 1.1 1.0 1.4 1.1 0.9 0.2 0.3 1.4 0.9 1.2 1.0 1.4 1.2 1.2 0.8 1.1 0.4 0.7 1.1 1.4 1.0 1.0 1.6 1.0 1.3 1.3 1.1 0.5 1.0 0.4 1.3 1.3 1.7 2.0 0.4 1.1\nDiverticular disease/diverticulitis (self-reported) 0.4 0.4 1.8 -0.8 -0.5 -0.2 -0.6 -0.5 -0.3 -0.1 0.3 -0.6 -0.8 -1.4 -1.0 -0.8 -0.3 -0.6 -0.9 -0.2 -0.7 -0.0 -0.2 -0.9 -0.6 -0.3 -1.1 0.0 -0.3 -0.6 -0.9 0.2 -0.4 -0.9 -0.9 -1.1 -1.1 -0.3 -0.7 -0.4 -0.5 -0.4 -0.3 -1.1 -0.3 -0.7 -0.7 -0.7 -1.0 -1.0 -0.7 0.0 0.1 -0.5 0.3 -0.5\nMedication: Atenolol 0.6 0.7 2.8 -0.9 -0.4 -0.1 -0.7 -0.4 0.2 -0.5 -0.6 -1.0 -1.3 -0.5 -0.9 -0.9 0.1 -0.5 -1.1 -0.5 -1.0 -0.7 -0.8 -0.9 -0.7 -0.7 -0.7 -1.5 -0.4 -0.9 -0.7 -0.5 -0.9 -0.9 -0.4 -1.5 -0.6 -0.3 -0.6 -1.7 -0.7 -0.8 -1.1 -0.8 -1.0 -0.9 -0.8 -0.9 -0.7 -0.4 -1.1 0.0 -0.6 -1.4 1.0 -1.1\nMedication: Levothyroxine sodium 2.4 4.0 8.3 -1.9 -2.1 -1.9 -1.6 -1.8 -2.2 -2.0 -1.2 -1.7 -1.8 -1.8 -1.9 -1.7 -2.0 -2.0 -1.9 -1.8 -2.1 -1.6 -2.6 -1.6 -1.9 -2.3 -1.6 -2.3 -2.3 -1.9 -1.8 -2.0 -2.1 -1.7 -1.8 -2.1 -1.9 -2.1 -2.2 -2.9 -2.3 -2.4 -2.1 -1.8 -2.1 -1.9 -1.8 -2.3 -1.9 -2.4 -1.9 -2.6 -2.0 -2.3 -1.6 -1.7\nSitting height 0.1 1.0 7.7 1.2 -0.0 0.5 0.2 0.6 0.3 0.4 -1.4 0.9 1.2 0.7 1.1 0.9 -0.9 0.1 1.5 0.9 1.0 -0.1 1.2 1.0 0.5 -0.7 0.5 1.2 1.0 1.0 0.7 0.6 0.9 1.0 0.3 2.0 0.9 0.6 1.4 2.8 0.8 1.5 1.1 0.9 1.3 0.8 0.8 1.5 0.6 1.4 0.9 1.1 1.0 1.1 -0.6 0.7\nChronic bronchitis/emphysema (father) 1.6 1.9 6.0 0.6 1.6 1.8 1.9 1.3 1.7 1.7 -0.4 1.3 0.6 0.9 0.8 0.8 1.7 1.4 0.9 1.6 1.5 2.4 1.4 0.6 1.3 1.6 1.0 1.7 1.3 1.5 0.2 1.8 1.4 0.6 0.9 0.5 0.6 1.7 0.9 1.4 1.9 1.4 1.8 0.8 1.3 1.1 0.9 1.3 1.6 1.1 1.3 1.7 1.5 1.0 2.5 1.6\nHigh blood pressure (mother) 4.5 6.3 11.1 -2.4 -2.2 -2.6 -2.4 -2.6 -2.7 -2.3 -1.6 -1.7 -2.2 -2.6 -2.5 -2.4 -2.4 -2.4 -2.3 -3.1 -2.5 -2.2 -2.7 -2.2 -2.5 -2.4 -3.1 -2.7 -2.7 -2.6 -2.2 -2.5 -2.9 -2.2 -2.6 -3.1 -3.1 -2.9 -3.3 -2.7 -2.6 -2.5 -2.0 -2.5 -2.2 -2.5 -2.3 -3.3 -2.2 -2.9 -2.5 -2.6 -1.0 -1.4 -2.3 -2.6\nBody mass index (BMI) 2.2 9.5 18.1 -3.4 -3.1 -2.7 -2.9 -3.1 -2.4 -3.1 -2.2 -3.1 -3.6 -3.5 -3.7 -3.7 -2.7 -3.4 -2.7 -2.1 -3.9 -3.1 -2.6 -3.6 -3.2 -2.3 -2.9 -3.7 -2.5 -3.0 -3.6 -3.3 -3.0 -3.6 -2.8 -2.6 -1.7 -2.0 -2.6 -3.2 -3.2 -3.6 -3.7 -3.4 -3.4 -3.4 -3.5 -2.1 -3.2 -1.0 -3.7 -2.1 -3.5 -4.3 -1.9 -3.1\nImpedance of leg (left) 0.2 0.8 7.8 0.4 -0.6 -0.9 -0.1 -0.6 -1.2 0.1 1.2 -1.1 0.4 -0.2 0.2 0.6 -0.5 -0.4 -1.0 -2.1 -0.1 0.2 -1.1 0.8 -0.5 -0.8 -0.4 0.1 -1.3 -0.4 0.8 0.1 -0.1 0.7 -0.5 -0.1 -1.7 -1.2 -0.3 -1.4 -1.0 -1.0 -0.2 -0.0 -0.0 0.4 0.2 -1.3 -0.8 -2.8 0.5 -1.6 -0.6 0.3 -1.8 0.6\nLeg predicted mass (left) 0.4 2.0 7.1 -1.5 -1.8 -1.2 -1.6 -1.4 -1.2 -1.8 -2.7 -1.1 -1.6 -1.8 -1.7 -1.9 -2.0 -1.9 -0.6 -0.5 -1.5 -1.9 -0.3 -2.0 -1.6 -1.5 -1.4 -1.3 -0.7 -1.1 -2.2 -1.6 -1.2 -1.9 -1.6 -0.4 -0.2 -0.7 -0.8 0.4 -1.1 -0.6 -1.4 -1.6 -1.2 -1.7 -1.8 -0.2 -1.0 1.0 -1.9 -0.5 -0.5 -1.4 -1.2 -1.8\nTrunk fat mass 2.9 12.6 21.2 -3.7 -3.9 -3.3 -3.3 -3.7 -3.2 -3.7 -3.1 -3.8 -3.9 -4.0 -4.1 -4.0 -3.4 -4.2 -3.2 -3.0 -4.1 -3.5 -3.1 -3.9 -3.9 -3.2 -3.4 -3.7 -3.0 -3.4 -3.9 -3.7 -3.5 -3.9 -3.4 -2.7 -2.4 -2.8 -2.9 -3.6 -4.0 -3.8 -4.2 -3.8 -3.7 -3.8 -3.9 -2.6 -3.7 -1.6 -4.1 -3.0 -3.8 -4.6 -2.6 -3.5\nWaist circumference 4.3 15.8 20.8 -4.4 -4.2 -3.8 -3.6 -4.0 -3.7 -4.4 -4.3 -4.3 -4.6 -4.3 -4.4 -4.5 -3.9 -4.4 -3.4 -3.2 -4.3 -4.0 -3.9 -4.5 -4.3 -3.9 -4.1 -4.4 -3.6 -4.0 -4.5 -4.3 -4.2 -4.5 -3.9 -3.8 -3.2 -3.5 -3.9 -3.3 -3.9 -3.9 -4.1 -4.3 -4.2 -4.5 -4.4 -3.5 -3.7 -2.1 -4.5 -2.9 -3.2 -4.0 -2.6 -4.1\nNumber of incorrect matches in round 0.1 0.1 1.2 -0.1 0.2 -0.0 -0.4 -0.2 0.0 0.4 0.0 -0.1 0.0 -0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 -0.0 -0.4 0.1 -0.0 -0.2 -0.8 -0.4 -0.0 -0.3 -0.3 0.1 -0.3 -0.0 -0.3 -0.8 -1.1 -0.3 -0.8 0.4 0.2 0.0 0.6 -0.2 0.3 -0.2 -0.0 -0.7 -0.3 -0.5 0.0 0.7 0.4 1.0 -0.1 -0.1\nPast tobacco smoking 0.5 0.8 9.2 1.2 0.6 0.6 0.4 0.6 0.1 0.5 3.0 1.2 0.9 0.7 0.8 1.0 -0.2 0.5 -0.0 0.6 0.6 0.3 1.0 1.2 0.8 0.7 1.3 1.4 0.6 0.7 1.1 0.6 1.2 1.2 0.8 1.6 1.3 0.6 1.0 0.4 0.3 0.4 0.2 0.7 0.8 1.2 0.9 1.2 0.6 0.2 0.8 -0.2 -0.7 0.5 -0.5 1.0\nAlcohol usually taken with meals 1.1 1.7 5.4 1.6 1.2 1.3 0.5 1.4 1.5 0.9 0.8 1.6 1.1 1.7 1.4 1.3 1.2 1.3 2.1 1.5 0.8 -0.2 1.8 1.5 1.2 0.9 2.3 0.1 1.9 0.9 1.6 0.7 1.0 1.4 1.5 1.6 2.0 1.3 1.4 1.1 0.9 1.3 0.6 1.4 1.1 1.2 1.3 1.6 0.7 2.3 0.7 1.7 0.7 0.6 0.9 0.5\nNervous feelings 0.1 0.2 1.1 -0.3 0.4 0.3 -0.4 0.2 0.5 0.1 0.4 0.4 -0.1 0.3 0.0 -0.2 0.9 0.7 0.2 0.4 0.0 -0.1 0.0 -0.4 0.4 0.6 0.4 -0.0 0.3 -0.2 -0.2 0.1 0.1 -0.3 0.2 -0.1 0.7 -0.1 -0.2 0.4 0.9 0.5 0.3 0.1 -0.2 -0.1 -0.0 -0.2 0.3 0.6 0.0 1.0 0.4 0.6 1.0 -0.1\nFrequency of tenseness / restlessness in last 2 weeks 0.6 0.9 1.9 -1.0 -0.9 -1.0 -0.4 -1.1 -0.8 -0.8 0.3 -0.6 -0.9 -1.2 -1.0 -1.0 -0.4 -0.5 -1.1 -0.7 -1.2 -0.4 -1.3 -0.9 -0.8 -0.6 -1.2 -1.2 -1.2 -0.5 -1.2 -0.7 -1.0 -1.0 -1.1 -1.2 -1.3 -0.9 -1.1 -0.9 -0.7 -0.9 -0.5 -1.1 -1.0 -1.1 -1.0 -1.3 -1.4 -1.3 -0.8 -0.0 -0.1 -0.2 -0.9 -1.0\nHearing difficulty/problems with background noise 1.2 2.0 4.8 1.2 2.2 1.6 1.0 1.6 2.2 1.7 2.1 1.2 1.0 1.0 1.3 1.1 1.8 1.6 1.5 1.7 1.2 1.0 1.5 1.1 1.8 1.7 1.2 1.2 1.8 1.0 1.4 1.4 1.5 1.2 1.5 0.9 1.9 1.0 0.6 1.2 1.5 1.7 1.2 1.1 1.5 1.3 1.3 1.1 1.0 1.5 1.1 1.3 1.4 1.1 1.7 0.9\nHair/balding pattern: Pattern 2 0.2 0.2 0.7 -0.5 -0.4 -0.6 -0.7 -0.7 -0.6 -0.4 -0.2 -0.1 -0.2 -0.4 -0.4 -0.5 -0.2 -0.2 -0.1 -0.6 -0.2 -0.4 -0.0 -0.5 -0.5 0.2 -0.7 -0.4 -0.6 -0.4 -0.6 -0.5 -0.3 -0.6 -0.7 -0.2 -0.6 -0.6 -0.5 0.6 0.2 -0.0 0.1 -0.5 -0.3 -0.4 -0.5 -0.7 0.1 -0.7 -0.3 -0.3 0.5 0.6 -0.8 -0.4\nHad menopause 0.3 0.4 2.7 -0.7 -0.2 0.0 0.0 -0.2 -0.1 -0.4 0.3 -1.1 -0.9 -0.5 -0.8 -0.7 0.2 -0.2 -0.2 0.6 -0.9 -0.2 -0.3 -0.7 -0.3 -0.5 -0.0 -0.9 -0.1 -0.3 -0.4 -0.6 -0.4 -0.8 0.0 -0.6 -0.0 -0.1 -0.5 -1.6 -0.3 -0.6 -0.8 -0.4 -0.8 -0.7 -0.6 -0.1 -0.3 0.4 -0.8 -0.3 -1.1 -1.2 0.8 -0.4\nHad other major operations 0.5 0.7 2.7 0.7 0.9 1.1 0.2 1.0 1.3 0.8 1.7 0.0 0.6 0.8 0.5 0.6 1.1 0.8 0.5 0.9 0.1 0.2 1.1 0.6 0.7 0.8 1.1 -0.3 1.2 0.3 0.8 0.8 0.7 0.6 1.0 0.6 1.3 1.0 1.2 -0.4 0.3 0.2 0.0 0.9 0.3 0.6 0.7 1.2 0.1 1.0 0.2 0.7 -1.0 -0.3 1.2 0.7\nForced vital capacity (FVC) 0.2 0.7 3.7 0.7 0.6 0.5 0.5 0.2 0.3 0.8 1.3 0.2 0.7 -0.1 0.3 0.4 -0.3 0.4 1.2 0.4 0.5 0.9 1.5 0.5 0.6 0.2 -0.5 1.1 0.8 1.4 0.2 1.0 1.1 0.6 0.3 1.4 0.8 0.8 0.9 1.3 1.0 1.3 0.8 0.1 0.9 0.8 0.4 0.6 0.6 1.0 0.6 0.3 1.9 0.7 -0.4 0.7\nHeel bone mineral density (BMD) T-score, automated (right) 1.0 2.2 7.3 1.3 1.6 1.5 1.7 1.6 2.0 1.3 1.8 1.1 1.4 1.5 1.4 1.4 1.8 1.4 1.3 2.1 1.4 1.3 1.3 1.2 1.6 2.0 1.7 0.8 1.8 1.6 1.3 1.1 1.6 1.2 2.1 1.6 2.7 1.6 1.6 1.1 1.1 1.2 0.9 1.6 1.2 1.3 1.4 2.0 1.3 2.0 1.3 0.9 0.5 0.3 1.6 1.1\nEver unenthusiastic/disinterested for a whole week 0.8 0.9 3.4 -0.8 -0.6 -0.8 -1.2 -0.9 -0.6 -0.4 -0.5 -1.0 -0.8 -1.0 -0.8 -0.9 -0.6 -0.7 -1.2 -0.8 -1.1 -0.6 -0.9 -0.8 -1.2 -0.2 -1.6 -1.2 -0.9 -0.8 -0.9 -0.4 -0.9 -0.7 -1.4 -1.3 -1.7 -0.4 -0.9 -0.6 -0.9 -1.8 -0.4 -1.2 -0.8 -0.8 -0.9 -1.0 -1.4 -1.3 -0.7 0.7 -1.8 -0.1 -1.1 -0.6\nQualifications: None of the above 0.1 0.3 3.5 -0.2 0.3 0.5 1.0 0.4 0.7 0.1 -0.2 -0.3 -0.0 0.5 -0.1 0.0 0.4 0.1 0.1 0.9 0.4 0.8 0.2 -0.3 0.2 0.6 0.3 0.4 0.6 0.3 0.2 0.1 0.2 -0.3 0.7 0.0 0.4 0.8 0.5 -0.5 0.2 0.1 -0.0 0.6 -0.0 -0.0 0.2 0.8 0.7 1.0 0.1 -0.2 0.2 -0.7 1.9 0.5\nFinancial difficulties in last 2 years 3.6 4.8 7.5 -2.5 -2.3 -1.9 -1.7 -2.2 -2.0 -2.3 -2.5 -2.4 -2.0 -2.2 -2.2 -2.3 -1.9 -2.1 -1.9 -1.9 -2.2 -1.9 -2.5 -2.4 -2.2 -1.8 -2.0 -2.6 -2.3 -2.2 -2.2 -2.0 -2.5 -2.3 -2.0 -2.7 -2.1 -2.3 -2.6 -2.5 -2.5 -2.3 -1.9 -2.1 -2.2 -2.4 -2.1 -2.7 -2.3 -2.3 -2.2 -2.2 -0.6 -1.9 -1.3 -2.3\nMouth/teeth dental problems 0.1 0.1 1.0 -0.0 -0.0 -0.1 -0.4 -0.3 -0.7 0.0 0.5 -0.7 0.1 -0.3 -0.2 -0.1 -0.6 -0.2 -0.2 -0.5 -0.2 -0.2 0.4 -0.0 -0.2 -0.3 -0.7 0.2 -0.2 -0.1 -0.2 -0.2 0.1 0.0 -0.2 0.2 0.1 0.2 -0.4 0.0 -0.2 -0.6 -0.0 -0.3 0.0 0.2 -0.1 -0.1 0.3 -0.4 -0.0 -0.6 0.2 0.2 -1.0 -0.0\nHeart attack 0.2 0.3 1.8 -0.4 -0.5 -0.4 -0.6 -0.4 -0.4 -0.4 0.2 -1.4 -0.5 -0.3 -0.4 -0.4 -0.4 -0.4 -0.6 -1.0 -0.5 -0.4 -0.3 -0.3 -0.5 -0.5 -0.2 -1.0 -0.6 -0.5 -0.3 -0.4 -0.6 -0.3 -0.6 -0.7 -0.7 -0.4 -0.4 -0.5 -0.5 -0.6 -0.4 -0.5 -0.5 -0.3 -0.4 -0.6 -0.5 -0.8 -0.4 -0.1 -0.4 0.1 -0.5 -0.5\nAllergy 1.3 3.0 17.5 1.3 1.6 1.0 2.3 1.0 0.5 1.7 -0.2 0.7 1.7 1.0 1.5 1.4 0.4 0.9 1.7 -0.0 2.4 3.2 2.2 1.2 1.0 1.8 -0.4 2.8 1.1 2.3 1.0 2.2 2.0 1.3 0.3 1.8 -0.2 1.4 1.8 4.2 1.6 1.8 2.9 0.9 2.2 1.8 1.3 2.1 1.4 0.0 2.5 1.5 1.3 2.6 0.1 2.8\nPain all over the body in last month 0.3 0.3 1.6 -0.3 0.0 -0.3 -0.4 -0.3 -0.0 -0.3 1.3 0.3 -0.5 0.2 -0.1 -0.2 0.6 0.2 -0.7 -0.6 -0.4 -0.6 -0.7 -0.1 -0.3 0.6 0.5 -0.7 -0.7 -0.6 -0.0 -0.7 -0.4 -0.2 -0.0 -0.6 0.3 -0.6 -0.8 -0.9 -0.6 -0.5 -0.6 -0.3 -0.8 -0.3 -0.3 -0.8 -0.2 -0.9 -0.5 -0.9 0.3 0.2 -0.4 -0.8\nDiabetes (self-reported) 5.0 7.7 15.5 -3.1 -2.5 -2.6 -1.5 -2.6 -2.8 -2.5 -2.3 -2.5 -2.9 -2.7 -2.9 -2.8 -2.8 -2.6 -3.2 -2.5 -2.7 -1.3 -3.3 -2.7 -2.8 -2.9 -3.4 -2.4 -3.2 -2.4 -2.9 -2.3 -3.0 -2.9 -3.0 -3.6 -3.9 -2.7 -3.2 -3.0 -2.7 -3.2 -2.1 -2.8 -2.8 -2.8 -2.8 -3.2 -2.8 -3.7 -2.5 -2.4 -2.1 -2.2 -1.6 -1.9\nHayfever/allergic rhinitis (self-reported) 0.2 0.3 3.7 -0.4 -0.2 0.0 -0.5 -0.4 0.0 -0.2 0.3 -0.3 -0.6 -0.6 -0.7 -0.4 0.1 -0.2 -0.6 0.3 -1.0 -0.6 -0.3 -0.3 -0.3 -0.2 0.3 -1.1 -0.2 -0.4 -0.4 -0.4 -0.4 -0.4 -0.1 -0.6 0.1 -0.1 -0.6 -1.9 -0.3 -0.8 -0.9 -0.4 -0.7 -0.5 -0.4 -0.7 -0.2 0.2 -0.8 -0.6 -0.1 -1.2 0.2 -0.6\nMedication: Ramipril 6.6 8.5 14.9 -3.1 -2.6 -3.0 -2.4 -3.0 -2.8 -2.9 -1.6 -2.6 -3.3 -3.2 -3.1 -3.2 -1.9 -2.5 -3.1 -3.2 -3.1 -2.2 -2.9 -3.1 -3.1 -1.5 -3.4 -2.9 -3.1 -2.8 -3.1 -2.9 -3.4 -3.1 -3.0 -3.9 -3.5 -2.9 -3.4 -3.3 -2.7 -2.9 -2.6 -3.3 -3.1 -3.2 -3.1 -3.7 -2.7 -3.3 -3.0 -2.3 -1.1 -2.2 -2.0 -3.1\nMedication: Simvastatin 1.2 1.7 10.0 -0.9 -0.5 -0.8 -0.8 -0.4 -0.5 -1.0 -1.4 -0.0 -1.1 -0.5 -0.7 -0.7 -0.3 -0.4 -1.5 -0.8 -1.3 -1.2 -2.0 -0.6 -1.1 -0.7 -1.2 -2.2 -1.1 -1.6 -0.5 -1.4 -2.0 -0.7 -0.7 -3.0 -2.2 -1.0 -2.0 -3.2 -1.4 -1.7 -1.2 -0.7 -1.2 -1.4 -0.6 -2.3 -1.1 -1.7 -1.2 -0.3 -0.6 -0.9 0.2 -1.8\nFluid intelligence score 0.1 0.3 2.4 -0.1 0.4 0.3 -0.7 0.3 0.2 -0.3 -0.5 0.6 -0.3 0.4 -0.0 -0.2 0.3 -0.0 0.9 0.8 -0.3 -1.2 0.2 -0.2 0.4 -0.0 0.9 -0.4 0.6 -0.6 0.1 -0.7 0.0 -0.2 0.3 0.2 1.6 -0.1 -0.6 -0.4 0.3 0.2 -0.6 0.1 -0.2 -0.2 -0.1 0.1 0.9 1.5 -0.6 -0.3 -0.6 -0.3 0.3 -0.8\nIllnesses of siblings 2.4 3.4 10.5 2.3 1.9 1.6 2.0 1.8 1.4 1.9 0.9 2.1 2.5 2.0 2.4 2.4 0.1 1.9 1.6 1.2 1.9 1.7 1.9 2.5 1.5 1.4 0.9 1.7 1.4 1.9 2.2 1.9 1.5 2.5 1.2 1.0 0.3 1.5 1.5 2.2 1.5 1.2 2.7 1.9 2.3 2.1 2.2 1.0 1.3 -0.3 2.4 2.6 1.4 3.2 0.3 1.8\nNeuroticism score 2.3 4.7 9.1 -2.8 -1.9 -2.0 -2.4 -2.3 -1.5 -1.8 -0.2 -1.8 -2.8 -2.7 -2.7 -2.8 -1.2 -1.7 -2.2 -2.1 -2.6 -1.6 -1.8 -2.9 -2.0 -1.5 -2.6 -2.1 -2.3 -2.0 -3.0 -1.8 -2.2 -2.9 -2.5 -2.4 -1.7 -2.1 -2.1 -1.4 -1.5 -1.9 -1.9 -2.7 -2.6 -2.5 -2.7 -2.2 -2.4 -2.2 -2.5 -0.7 -1.6 -1.5 -1.2 -2.2\nWeight 1.4 6.8 10.6 -2.7 -3.1 -2.5 -2.6 -2.8 -2.4 -2.9 -3.1 -2.7 -3.0 -3.1 -3.0 -3.1 -3.0 -3.3 -1.8 -1.9 -3.1 -3.0 -1.8 -3.0 -2.9 -2.6 -2.5 -3.0 -2.0 -2.4 -3.2 -2.9 -2.5 -3.0 -2.7 -1.6 -1.4 -1.8 -2.0 -1.6 -2.5 -2.3 -2.9 -2.9 -2.6 -2.9 -3.0 -1.5 -2.5 -0.3 -3.1 -1.7 -2.2 -3.2 -2.2 -2.7\nImpedance of arm (right) 0.2 0.9 4.7 -0.3 -0.9 -1.1 -0.9 -0.6 -1.1 -0.7 0.1 -1.0 -0.2 -0.3 -0.2 -0.1 -0.5 -0.8 -1.2 -1.4 -0.5 -0.9 -1.5 -0.0 -0.7 -0.5 -0.2 0.0 -0.9 -1.3 0.2 -0.6 -0.8 -0.0 -0.3 -0.6 -1.2 -1.7 -0.8 -2.1 -1.4 -0.8 -1.2 -0.2 -0.8 -0.5 -0.2 -1.4 -1.1 -1.6 -0.4 -2.2 -0.8 -1.1 -0.9 -0.5\nArm fat percentage (right) 3.8 15.2 27.6 -4.1 -3.9 -3.6 -3.5 -3.9 -3.2 -3.9 -2.6 -4.0 -4.2 -4.2 -4.5 -4.3 -3.2 -4.2 -3.8 -3.1 -4.7 -3.7 -3.6 -4.2 -4.1 -2.8 -3.8 -4.1 -3.3 -3.9 -4.2 -3.9 -4.0 -4.2 -3.4 -3.6 -2.9 -3.0 -3.4 -4.8 -4.4 -4.6 -4.7 -4.1 -4.3 -4.3 -4.1 -3.2 -4.3 -2.2 -4.4 -3.2 -4.3 -5.2 -2.6 -3.9\nTrunk fat-free mass 0.2 1.0 8.8 -0.7 -1.3 -0.8 -1.1 -1.0 -1.0 -1.1 -3.0 -0.7 -0.7 -1.4 -0.9 -1.1 -2.1 -1.4 0.4 -0.3 -0.7 -1.3 0.2 -1.1 -1.1 -1.8 -1.1 -1.0 -0.3 -0.4 -1.5 -1.0 -0.6 -1.0 -1.4 0.2 -0.4 -0.2 -0.4 1.6 -0.2 0.1 -0.2 -1.0 -0.2 -1.0 -1.0 0.1 -0.4 1.0 -0.9 0.3 0.4 -0.2 -1.3 -1.0\nHip circumference 0.7 3.1 6.6 -1.9 -1.9 -1.5 -2.0 -1.8 -1.2 -1.9 -1.9 -2.0 -2.1 -2.3 -2.2 -2.2 -1.7 -2.2 -0.8 -1.0 -2.3 -2.3 -1.0 -2.2 -1.8 -1.7 -1.6 -2.1 -1.0 -1.8 -2.2 -2.0 -1.7 -2.2 -1.6 -1.0 -0.5 -1.1 -1.4 -1.3 -1.6 -1.5 -2.2 -1.9 -1.8 -2.1 -2.1 -0.8 -1.7 0.4 -2.4 -1.1 -1.4 -2.6 -1.1 -1.9\nTime employed in main current job 1.2 1.4 3.3 -1.5 -1.0 -1.3 -0.7 -1.3 -1.4 -1.2 -1.7 -0.6 -1.7 -1.2 -1.3 -1.4 -0.8 -1.3 -0.8 -1.3 -0.8 -0.5 -1.1 -1.3 -1.3 -0.8 -1.4 -0.6 -1.5 -1.0 -1.6 -1.1 -1.2 -1.4 -1.7 -1.5 -1.3 -1.5 -1.5 0.2 -0.7 -0.5 -0.6 -1.6 -1.2 -1.2 -1.5 -1.6 -0.7 -1.8 -1.0 -1.1 0.2 -0.3 -0.9 -1.1\nAlcohol intake versus 10 years previously 0.3 0.4 3.6 -0.8 -0.2 -0.3 0.4 -0.3 -0.3 -0.2 -1.1 -0.2 -0.6 -0.7 -0.5 -0.5 -0.4 -0.4 -0.8 -0.5 -0.1 0.8 -0.7 -0.5 -0.6 -0.4 -1.3 0.5 -0.8 -0.2 -0.5 0.1 -0.6 -0.6 -0.8 -1.6 -1.7 -0.6 -0.6 -0.5 -0.1 -0.3 0.3 -0.7 -0.4 -0.5 -0.5 -1.0 -0.4 -1.9 -0.0 -0.3 0.0 -0.1 0.3 0.2\nFather’s age at death 2.1 2.8 7.7 1.4 1.6 1.9 1.4 1.5 2.0 1.7 0.4 1.2 1.0 2.0 1.3 1.3 1.3 1.6 1.1 2.0 1.5 1.6 2.5 1.3 1.2 2.2 1.9 1.4 1.9 1.8 1.1 1.8 1.9 1.2 1.0 2.0 1.5 2.1 2.2 2.4 1.7 1.6 1.5 1.2 1.5 1.6 1.2 2.3 1.4 2.2 1.5 2.8 1.3 1.8 1.6 1.5\nWorrier / anxious feelings 3.1 5.9 10.0 -2.8 -2.0 -2.4 -2.9 -2.5 -1.9 -2.5 -1.5 -2.1 -3.0 -2.5 -2.8 -2.9 -1.2 -2.0 -2.2 -2.0 -2.9 -2.5 -2.3 -3.0 -2.6 -1.1 -2.4 -2.7 -2.2 -2.7 -2.7 -2.6 -2.5 -2.9 -2.2 -2.5 -1.5 -2.2 -2.3 -2.2 -2.2 -2.5 -2.7 -2.8 -3.2 -2.8 -2.9 -2.3 -2.3 -1.5 -3.0 -1.4 -2.7 -2.2 -1.5 -2.9\nFrequency of tiredness / lethargy in last 2 weeks 0.9 1.5 4.1 -1.4 -0.8 -0.9 -0.4 -1.1 -0.4 -0.9 -0.5 -1.1 -1.1 -1.5 -1.4 -1.3 -0.8 -1.0 -1.0 -0.3 -1.6 -0.3 -1.3 -1.4 -1.0 -0.6 -1.8 -1.2 -0.8 -0.9 -1.4 -0.7 -1.4 -1.3 -1.2 -1.9 -1.9 -0.5 -1.3 -1.9 -1.3 -1.9 -1.0 -1.3 -1.3 -1.5 -1.1 -1.1 -1.9 -1.0 -1.2 -0.1 -2.0 -1.8 -0.3 -0.7\nFalls in the last year 0.2 0.3 1.5 0.4 0.1 0.0 0.2 0.0 -0.3 0.2 0.8 -0.6 0.4 -0.0 0.2 0.4 -0.6 -0.1 -0.2 -0.6 -0.4 -0.0 -0.4 0.6 -0.2 -1.0 -0.5 -1.1 -0.4 -0.2 0.4 -0.1 -0.4 0.6 -0.2 -0.7 -1.0 0.0 -0.4 -1.2 -0.4 -1.1 0.1 0.0 0.0 0.1 0.3 -0.7 0.0 -1.1 0.2 0.2 -0.8 0.7 -0.8 0.0\nHair/balding pattern: Pattern 3 0.3 0.5 1.8 0.8 0.8 0.9 1.0 0.9 0.7 0.7 0.9 0.0 0.6 0.7 0.8 0.8 0.4 0.6 1.0 1.3 0.6 0.4 0.2 0.9 0.7 0.3 0.3 -0.2 0.8 0.5 0.9 0.3 0.4 0.9 1.1 0.2 0.4 0.8 0.3 -0.1 0.6 0.5 0.5 0.8 0.6 0.5 0.8 0.3 1.2 0.9 0.6 0.5 0.6 0.5 1.1 0.1\nNumber of live births 1.6 2.3 5.3 -1.7 -1.6 -1.4 -1.5 -1.5 -1.3 -1.3 -0.6 -1.3 -1.4 -1.3 -1.7 -1.4 -1.0 -1.4 -2.1 -1.3 -1.8 -1.3 -1.8 -1.4 -1.6 -1.7 -1.0 -1.8 -1.8 -1.5 -1.7 -1.4 -1.6 -1.6 -1.2 -1.8 -1.3 -1.5 -1.2 -2.3 -1.6 -1.8 -1.7 -1.3 -2.0 -1.5 -1.5 -1.8 -1.3 -1.7 -1.5 -1.6 -0.9 -1.4 -0.8 -1.4\nForced expiratory volume in 1-second (FEV1) 2.0 6.6 14.8 -2.4 -2.9 -2.8 -2.7 -3.1 -3.3 -2.4 -1.4 -3.0 -2.4 -3.4 -3.0 -2.7 -3.9 -3.2 -1.7 -2.9 -2.8 -2.2 -1.7 -2.5 -2.8 -3.0 -3.8 -1.8 -2.6 -1.9 -3.0 -2.1 -2.0 -2.5 -3.0 -1.4 -2.2 -2.4 -2.1 -1.4 -2.4 -2.0 -2.3 -3.2 -2.2 -2.3 -2.8 -2.4 -2.4 -1.9 -2.5 -2.8 -1.1 -2.4 -3.6 -2.2\nPulse rate 0.2 0.3 2.0 -0.6 0.0 -0.2 -0.2 -0.0 -0.3 -0.5 -1.4 -0.3 -0.6 0.2 -0.3 -0.4 -0.2 -0.2 -0.2 0.1 -0.3 -0.5 -0.5 -0.4 -0.6 0.3 -0.5 -0.7 -0.2 -0.7 -0.3 -0.7 -0.9 -0.4 -0.4 -1.3 -1.1 -0.6 -1.3 -0.8 -0.5 -0.4 -0.1 -0.3 -0.5 -0.6 -0.3 -1.0 0.3 -0.2 -0.5 -0.1 0.3 0.5 0.5 -1.1\nHappiness 0.2 0.2 1.7 0.3 0.3 0.5 -0.3 0.3 0.3 0.7 0.2 0.6 0.5 0.1 0.3 0.3 0.2 0.7 -0.2 -0.1 0.3 0.4 0.5 0.3 0.3 0.5 0.2 0.6 0.0 0.4 0.2 0.9 0.5 0.4 -0.3 0.1 -0.1 0.5 0.3 0.9 0.5 -0.1 1.0 0.1 0.6 0.4 0.3 0.2 -0.2 -0.5 0.5 1.3 -0.2 1.1 -0.2 0.8\nNoisy workplace 0.2 0.2 1.1 -0.8 -0.1 -0.2 0.3 -0.4 -0.1 -0.2 0.3 -0.2 -0.4 -0.9 -0.6 -0.6 0.2 -0.2 0.0 -0.1 -0.3 0.4 -0.6 -0.8 -0.1 -0.3 -1.0 -0.2 -0.3 0.0 -0.6 -0.2 -0.4 -0.7 -0.4 -0.8 -0.4 -0.5 -0.9 0.1 0.1 0.1 0.3 -0.6 -0.1 -0.6 -0.5 -0.5 -0.1 -0.3 -0.3 -0.0 0.3 0.2 0.4 -0.4\nQualifications: A levels/AS levels or equivalent 0.1 0.2 1.6 0.4 0.1 0.3 -1.0 0.1 0.4 0.2 1.3 0.4 0.2 0.2 -0.0 0.1 -0.6 0.3 -0.1 0.2 -0.4 -0.9 0.6 0.2 0.1 -0.2 0.7 -1.1 0.2 -0.3 0.3 -0.0 0.1 0.2 -0.1 0.3 0.8 0.4 0.3 -0.5 -0.1 -0.3 -0.4 -0.1 0.1 0.2 0.1 0.1 -0.2 0.5 -0.3 0.9 -0.6 0.1 -0.6 -0.6\nSerious illness, injury or assault of a close relative in last 2 years 3.6 4.1 6.8 -2.4 -2.0 -2.2 -2.5 -2.2 -1.6 -2.1 -1.8 -1.8 -2.5 -2.2 -2.2 -2.5 -1.3 -1.7 -1.6 -1.3 -2.2 -2.1 -2.1 -2.6 -1.9 -1.9 -1.6 -2.0 -1.9 -2.3 -2.4 -2.1 -2.2 -2.5 -2.2 -1.9 -1.9 -2.1 -2.1 -1.0 -1.7 -1.6 -1.9 -2.3 -2.3 -2.5 -2.4 -1.8 -2.3 -0.7 -2.4 -0.6 -2.0 -1.6 -1.5 -2.4\nMouth/teeth dental problems: Dentures 1.6 2.7 6.9 -2.0 -1.6 -1.3 -0.9 -1.4 -1.4 -1.8 -2.6 -1.5 -1.8 -1.2 -1.6 -1.7 -1.0 -1.6 -1.6 -1.0 -1.5 -1.3 -2.2 -1.9 -1.4 -1.2 -0.9 -2.0 -1.4 -1.8 -1.6 -1.8 -2.0 -1.9 -1.2 -2.2 -1.3 -1.6 -1.6 -2.2 -1.5 -1.3 -1.7 -1.4 -1.9 -2.0 -1.6 -1.9 -1.3 -1.0 -1.8 -1.6 -0.6 -2.5 0.1 -1.9\nAsthma 0.9 1.8 11.2 -1.0 -1.1 -1.0 -1.5 -0.9 -0.6 -0.9 -0.3 -0.8 -1.0 -1.3 -1.2 -1.0 -0.8 -1.0 -1.4 -0.6 -2.0 -1.7 -1.5 -0.8 -1.0 -1.1 -0.9 -1.4 -0.9 -1.5 -1.0 -1.0 -1.6 -0.8 -0.8 -1.8 -1.1 -0.8 -1.2 -3.3 -1.5 -2.0 -1.9 -0.9 -1.6 -1.3 -0.9 -1.8 -1.9 -1.2 -1.5 -1.0 -1.3 -2.2 -0.6 -1.3\nMedication: Ibuprofen (e.g. Nurofen) 0.9 1.1 3.0 -1.0 -1.2 -0.9 -1.1 -1.0 -1.1 -1.2 -1.3 -1.2 -0.9 -0.7 -0.8 -1.0 -1.3 -0.7 -0.8 -0.9 -0.8 -1.3 -1.4 -1.1 -1.0 -0.8 -0.4 -1.7 -1.2 -1.3 -0.7 -1.2 -1.3 -0.9 -1.1 -1.5 -0.9 -1.5 -1.7 -0.9 -0.9 -0.7 -0.7 -0.8 -0.9 -1.1 -0.9 -1.6 -0.7 -1.4 -1.0 -1.0 0.6 -0.3 -0.4 -1.3\nMedication: Cholesterol lowering 1.6 2.5 11.3 -1.4 -1.8 -1.1 -0.9 -1.1 -1.3 -1.7 -1.8 -1.4 -1.3 -1.3 -1.5 -1.3 -1.6 -1.6 -1.3 -0.9 -1.7 -1.5 -2.2 -1.3 -1.4 -1.6 -0.5 -2.1 -1.3 -1.7 -1.2 -1.5 -1.9 -1.4 -1.0 -2.1 -1.7 -1.0 -1.6 -3.4 -1.8 -2.0 -1.8 -1.2 -1.6 -1.6 -1.1 -1.7 -1.2 -1.0 -1.6 -1.4 -1.9 -2.6 -0.0 -1.7\nDepression (self-reported) 0.5 0.6 1.6 0.8 0.5 0.7 1.0 0.6 0.8 0.8 0.5 0.7 1.1 0.4 0.8 0.9 0.2 0.6 0.9 0.5 0.7 0.9 0.5 0.8 0.9 -0.1 0.7 1.1 0.6 1.0 0.6 1.0 0.7 0.9 0.7 0.7 0.1 0.8 1.0 0.5 0.8 0.7 0.9 1.0 0.9 0.8 0.9 0.8 0.3 0.4 1.1 0.8 0.6 0.4 0.6 1.3\nMedication: Lansoprazole 0.1 0.1 0.7 0.2 0.0 0.3 0.2 0.3 0.4 0.3 0.1 0.4 0.5 0.2 0.3 0.4 0.4 0.6 -0.7 0.0 0.1 0.1 -0.3 0.5 0.2 0.5 0.5 -0.3 -0.0 0.2 0.2 0.3 -0.1 0.3 0.2 -0.5 -0.2 0.2 -0.2 -0.6 -0.3 -0.2 0.2 0.3 0.2 0.1 0.4 -0.3 -0.4 -0.8 0.1 0.4 0.5 0.3 0.5 -0.2\nProspective memory result 0.5 0.6 1.8 -0.6 -0.9 -0.8 -1.4 -0.8 -0.8 -0.8 -0.1 -1.2 -0.8 -0.7 -0.7 -0.7 0.2 -0.5 -0.8 -1.2 -0.7 -1.1 -0.8 -0.7 -0.9 -0.9 -0.3 -1.2 -1.0 -0.9 -0.7 -0.7 -0.4 -0.7 -0.5 -0.1 0.2 -0.7 -0.3 -0.2 -1.2 -0.9 -1.0 -0.6 -0.7 -0.5 -0.8 -0.2 -1.1 -1.0 -0.8 -1.2 -0.6 -1.0 -1.0 -0.4\nLung cancer (father) 0.1 0.1 1.5 -0.0 -0.2 -0.3 0.3 -0.2 -0.6 -0.4 -0.4 -0.1 -0.1 0.1 0.1 -0.0 -0.6 -0.3 -0.1 0.3 0.3 0.1 -0.3 -0.1 -0.0 -0.4 0.4 0.2 -0.2 0.1 -0.2 -0.4 0.2 -0.1 -0.0 0.6 0.2 -0.1 0.2 0.8 0.2 0.2 0.1 0.1 -0.1 0.0 -0.1 0.6 0.5 0.5 0.1 -0.3 -1.2 -0.2 0.0 0.3\nIllnesses of mother 0.5 0.7 2.4 0.6 0.7 0.9 1.1 0.9 0.7 0.6 -0.8 1.2 0.5 1.2 0.8 0.6 0.4 0.8 0.6 1.4 0.8 0.9 0.7 0.5 0.4 1.5 1.2 1.2 0.8 0.7 0.5 0.7 0.6 0.6 0.6 0.4 0.7 0.9 0.7 0.8 0.9 0.7 0.8 0.7 0.5 0.6 0.7 0.9 1.0 0.6 0.8 1.0 0.7 0.7 1.2 0.7\nForced expiratory volume in 1-second (FEV1), Best measure 3.2 10.3 23.6 -3.0 -3.4 -3.4 -3.6 -3.7 -3.9 -2.9 -1.7 -3.8 -2.9 -4.1 -3.5 -3.3 -4.9 -3.9 -2.7 -3.4 -3.5 -2.9 -2.6 -3.0 -3.4 -3.8 -4.5 -2.3 -3.2 -2.8 -3.5 -2.6 -2.8 -3.0 -3.6 -2.3 -3.0 -3.1 -2.9 -2.3 -3.0 -2.8 -2.9 -3.8 -2.7 -2.9 -3.3 -3.2 -3.0 -2.6 -3.1 -3.1 -2.0 -2.9 -4.1 -2.7\nPulse wave Arterial Stiffness index 0.2 0.2 0.8 -0.5 -0.6 -0.3 -0.4 -0.3 -0.4 -0.7 -0.8 -0.3 -0.7 -0.4 -0.7 -0.6 -0.5 -0.4 -0.2 0.1 -0.5 -0.5 -0.4 -0.6 -0.5 -0.9 -0.0 -0.1 -0.3 -0.4 -0.5 -0.5 -0.4 -0.6 -0.3 -0.1 0.1 -0.0 -0.1 -0.6 -0.5 -0.3 -0.8 -0.3 -0.6 -0.5 -0.6 0.0 -0.3 0.3 -0.6 -0.5 0.2 -0.9 0.1 -0.4\nImpedance of arm (left) 0.1 0.3 2.1 0.4 0.0 -0.2 0.0 0.2 -0.1 0.3 1.2 -0.1 0.5 0.6 0.6 0.7 0.6 0.2 -0.5 -0.5 0.5 0.2 -0.6 0.7 0.3 0.5 0.6 1.2 -0.2 -0.3 0.9 0.3 0.1 0.7 0.7 0.1 -0.3 -0.8 0.1 -1.2 -0.5 0.1 -0.3 0.6 0.0 0.4 0.6 -0.4 -0.2 -1.1 0.5 -1.5 -0.2 -0.1 -0.0 0.3\nArm fat mass (right) 3.4 14.2 23.8 -3.9 -3.9 -3.5 -3.5 -3.9 -3.3 -3.9 -3.1 -3.9 -4.1 -4.2 -4.3 -4.2 -3.6 -4.3 -3.4 -3.0 -4.5 -3.8 -3.3 -4.1 -4.0 -3.2 -3.7 -4.1 -3.2 -3.6 -4.2 -3.9 -3.8 -4.1 -3.5 -3.2 -2.7 -2.8 -3.2 -3.9 -4.1 -4.2 -4.4 -4.1 -4.0 -4.1 -4.1 -2.9 -4.0 -1.8 -4.3 -2.9 -3.9 -4.9 -2.8 -3.8\nTrunk predicted mass 0.2 1.2 9.3 -0.8 -1.4 -0.9 -1.2 -1.1 -1.1 -1.3 -3.1 -0.8 -0.8 -1.5 -1.0 -1.2 -2.2 -1.5 0.3 -0.4 -0.9 -1.4 0.1 -1.2 -1.2 -1.9 -1.2 -1.1 -0.4 -0.5 -1.6 -1.1 -0.7 -1.1 -1.5 0.1 -0.4 -0.3 -0.5 1.5 -0.4 0.0 -0.3 -1.1 -0.3 -1.1 -1.1 0.0 -0.5 0.9 -1.1 0.2 0.2 -0.3 -1.3 -1.0\nStanding height 0.1 1.0 8.3 0.7 -1.0 -0.4 -0.2 -0.1 -0.9 -0.4 -2.8 -0.1 0.7 -0.2 0.6 0.4 -2.0 -0.6 1.3 -0.4 0.9 -0.5 0.8 0.4 -0.2 -1.6 -0.1 0.9 0.2 0.4 0.0 0.1 0.2 0.5 -0.6 1.5 -0.3 -0.4 0.5 2.9 0.5 1.9 0.9 0.3 1.1 0.2 0.2 0.5 0.5 0.8 0.5 0.2 2.2 1.5 -1.5 0.1\nLength of working week for main job 1.0 1.1 5.2 -0.7 -1.0 -1.3 -1.2 -1.3 -1.3 -1.0 -0.5 -0.6 -0.5 -1.3 -0.9 -0.8 -1.0 -1.0 -0.9 -1.6 -1.2 -1.4 -0.8 -0.7 -1.1 -1.2 -1.2 -1.2 -1.2 -1.0 -0.8 -1.3 -1.2 -0.7 -1.2 -0.7 -1.1 -1.2 -1.4 -0.4 -1.1 -1.1 -0.6 -1.0 -0.7 -1.0 -1.0 -1.4 -0.9 -0.9 -1.0 -0.6 -0.3 0.3 -2.3 -1.4\nExposure to tobacco smoke at home 0.4 0.4 3.7 -0.5 -0.7 -0.3 -0.4 -0.3 -0.4 -0.7 0.5 -0.2 -0.8 -0.3 -0.5 -0.6 -0.1 -0.7 -0.4 0.4 -0.6 -0.6 -0.8 -0.8 -0.3 -0.2 0.2 -0.4 -0.2 -0.8 -0.1 -0.6 -0.3 -0.6 0.1 -0.0 0.3 -0.2 -0.0 -1.5 -0.6 -0.5 -1.3 -0.3 -0.9 -0.5 -0.5 -0.0 -0.1 0.5 -0.8 -1.6 -1.1 -1.9 0.3 -0.4\nBreastfed as a baby 0.6 0.7 1.8 0.7 0.8 0.8 1.3 0.8 1.1 0.7 -0.5 0.8 0.5 0.7 0.8 0.6 1.0 0.8 1.1 0.9 0.8 1.2 0.9 0.6 0.6 1.2 1.0 0.8 1.0 1.1 0.5 0.9 0.6 0.6 0.6 0.4 0.2 0.7 0.8 0.7 1.3 1.0 1.0 0.8 0.7 0.6 0.7 0.7 0.7 0.6 0.8 1.1 0.4 0.8 0.9 1.2\nTense / ‘highly strung’ 0.3 0.4 2.0 -0.8 -0.5 -0.7 -1.1 -0.8 -0.5 -0.5 1.4 -0.4 -0.8 -0.9 -0.8 -0.8 0.1 -0.3 -0.7 -0.8 -0.8 -0.6 -0.3 -0.8 -0.6 -0.7 -0.5 -0.7 -0.7 -0.6 -1.2 -0.5 -0.5 -0.9 -0.6 -0.3 -0.3 -0.7 -0.3 -0.1 -0.3 -0.4 -0.6 -0.8 -0.9 -0.6 -0.8 -0.7 -0.5 -0.8 -0.6 0.0 -0.0 -0.0 -0.3 -0.8\nSeen doctor (GP) for nerves, anxiety, tension or depression 2.1 3.2 5.6 -2.1 -1.8 -1.7 -1.7 -2.0 -1.4 -1.4 -0.9 -1.6 -1.8 -2.3 -2.1 -2.0 -1.1 -1.7 -1.7 -2.2 -2.0 -1.0 -2.1 -2.0 -1.6 -1.9 -2.2 -1.7 -2.1 -1.7 -2.1 -1.1 -1.9 -2.0 -2.0 -2.3 -2.3 -1.7 -1.7 -1.7 -1.6 -1.9 -1.4 -2.1 -1.8 -1.9 -1.9 -1.9 -2.4 -2.2 -1.6 -0.7 -1.4 -1.5 -1.3 -1.3\nHair/balding pattern: Pattern 4 1.7 4.0 6.2 2.1 2.1 2.0 1.8 2.1 2.5 2.1 1.0 1.9 2.1 2.0 2.0 2.0 2.3 2.0 1.8 1.7 1.9 1.7 2.2 1.9 2.1 1.7 2.5 2.0 2.4 2.1 1.8 2.1 2.1 2.0 2.1 2.2 2.4 2.1 2.2 2.2 1.8 2.0 1.8 2.1 2.1 2.0 2.1 2.3 1.2 2.3 1.9 2.1 1.5 1.0 1.8 1.9\nBirth weight of first child 0.4 0.6 4.6 -0.4 -0.9 -1.1 -0.7 -0.9 -1.5 -0.8 -2.1 -0.8 -0.3 -0.7 -0.4 -0.4 -1.4 -1.0 0.1 -0.8 -0.4 -0.7 -0.5 -0.2 -0.9 -1.2 -1.2 -0.6 -0.9 -0.5 -0.8 -0.7 -0.5 -0.4 -1.1 -0.0 -1.2 -0.6 -0.4 0.9 -0.5 -0.5 -0.0 -0.7 -0.3 -0.5 -0.6 -0.6 -0.7 -0.7 -0.3 -0.4 -0.5 -0.1 -1.8 -0.2\nPeak expiratory flow (PEF) 2.7 6.4 15.6 -2.1 -3.1 -3.0 -2.6 -2.9 -3.2 -2.3 -1.6 -3.1 -2.1 -3.3 -2.6 -2.4 -3.6 -3.3 -1.4 -3.3 -2.5 -2.1 -2.0 -2.1 -2.6 -3.1 -3.9 -1.6 -2.7 -1.8 -2.7 -2.0 -2.1 -2.2 -3.1 -1.3 -2.6 -2.5 -1.8 -1.0 -2.5 -1.9 -2.2 -3.0 -2.1 -2.2 -2.6 -2.3 -2.8 -2.4 -2.1 -2.5 -1.1 -2.0 -4.0 -2.0\nPulse wave reflection index 1.7 2.1 7.1 -1.1 -1.7 -1.6 -1.5 -1.5 -1.6 -1.6 -1.1 -0.9 -1.1 -1.6 -1.5 -1.2 -1.5 -1.4 -1.3 -1.5 -1.6 -1.6 -1.6 -1.1 -1.3 -2.2 -0.9 -1.3 -1.6 -1.3 -1.3 -1.6 -1.2 -1.2 -1.0 -0.6 -0.5 -1.1 -0.7 -1.9 -1.8 -1.6 -2.0 -1.0 -1.5 -1.3 -1.3 -0.8 -1.6 -0.9 -1.5 -2.2 -1.3 -2.7 -1.6 -1.1\nEver highly irritable/argumentative for 2 days 1.7 2.1 4.4 -1.2 -1.5 -1.4 -1.4 -1.3 -1.4 -1.3 -0.6 -0.8 -0.9 -1.5 -1.3 -1.2 -1.4 -1.5 -1.9 -1.7 -1.6 -1.3 -1.6 -1.2 -1.5 -2.0 -1.3 -1.4 -1.6 -1.6 -1.1 -1.3 -1.5 -1.1 -1.3 -1.6 -1.4 -1.4 -1.3 -2.0 -1.7 -1.9 -1.4 -1.1 -1.3 -1.3 -1.1 -1.6 -1.6 -2.0 -1.3 -1.3 -2.1 -1.6 -1.1 -1.1\nLoud music exposure frequency 0.2 0.2 0.7 0.6 0.4 0.3 0.5 0.3 0.4 0.6 0.1 0.3 0.8 0.2 0.4 0.5 0.1 0.4 0.0 0.1 0.4 0.6 0.3 0.5 0.4 0.1 -0.0 0.9 0.3 0.8 0.5 0.8 0.6 0.6 0.1 0.5 -0.2 0.6 0.3 0.5 0.1 0.2 0.6 0.2 0.8 0.4 0.5 0.6 -0.1 0.0 0.6 0.7 -0.2 0.1 -0.2 0.5\nQualifications: O levels/GCSEs or equivalent 0.1 0.2 1.2 0.0 0.1 -0.3 -0.9 -0.2 -0.3 -0.4 1.1 0.3 0.0 0.1 -0.1 -0.1 0.2 0.2 -0.6 -0.1 -0.3 -1.0 -0.1 -0.2 -0.4 -0.1 0.1 -1.1 -0.3 -0.5 -0.1 -0.8 -0.3 0.0 -0.2 -0.2 0.1 -0.4 -0.6 -0.7 -0.3 -0.5 -0.4 -0.1 -0.3 -0.2 -0.1 -0.6 0.5 -0.1 -0.5 -0.2 -0.7 0.9 -0.9 -1.0\nMouth/teeth dental problems: Bleeding gums 2.2 2.9 4.3 1.8 1.6 1.6 1.7 1.8 2.1 1.7 2.0 1.9 1.6 1.6 1.7 1.8 1.7 1.8 1.4 2.0 1.7 1.8 1.5 1.7 1.7 1.6 1.9 1.5 1.7 1.8 1.8 1.8 1.9 1.7 1.6 1.9 1.4 1.6 1.9 1.3 1.8 1.6 1.4 1.7 1.6 1.7 1.7 1.9 1.4 1.5 1.8 1.7 0.1 1.1 1.6 1.9\nBlood clot in the leg (DVT) 1.4 1.9 5.3 -1.5 -1.0 -1.0 -1.4 -1.1 -0.8 -1.4 -1.3 -1.6 -1.6 -0.7 -1.1 -1.4 -0.8 -0.8 -1.5 -0.5 -1.5 -1.8 -1.8 -1.4 -1.1 -0.6 -0.9 -2.3 -1.0 -1.8 -1.2 -1.8 -1.8 -1.4 -0.7 -2.2 -0.9 -1.2 -2.1 -1.9 -0.8 -1.5 -1.3 -1.0 -1.6 -1.7 -1.3 -1.7 -0.9 -0.5 -1.7 -0.7 -1.2 -1.4 0.0 -1.5\nMedication: Paracetamol 3.0 5.0 9.1 -2.4 -2.1 -2.2 -1.7 -2.1 -2.4 -2.3 -2.6 -2.2 -2.1 -1.9 -2.1 -2.1 -1.8 -2.1 -2.3 -2.1 -2.1 -1.7 -2.6 -2.1 -2.5 -2.1 -2.2 -2.1 -2.3 -2.2 -2.2 -2.1 -2.6 -2.2 -2.3 -2.9 -2.9 -2.2 -2.7 -2.8 -2.2 -2.5 -1.9 -2.1 -2.4 -2.4 -2.1 -3.0 -1.8 -2.4 -2.0 -2.2 -0.4 -1.7 -1.2 -2.2\nHeadache pain in last month 6.7 11.5 19.8 -3.3 -3.5 -3.4 -4.4 -3.6 -3.8 -3.4 -1.6 -2.9 -3.6 -3.9 -3.6 -3.5 -3.5 -3.8 -3.0 -3.1 -4.0 -4.0 -2.9 -3.1 -3.6 -2.9 -3.1 -3.8 -3.3 -3.7 -3.5 -3.5 -2.7 -3.3 -3.4 -2.0 -2.0 -3.0 -3.0 -2.8 -3.9 -3.9 -4.0 -3.8 -3.4 -3.2 -3.6 -2.6 -3.5 -2.1 -3.8 -3.3 -4.5 -4.1 -3.4 -3.2\nMedication for cholesterol, blood pressure or diabetes 1.8 3.0 11.8 1.6 1.6 1.4 1.2 1.3 1.4 1.7 1.6 1.4 1.5 1.6 1.6 1.4 1.5 1.6 1.6 1.7 1.6 1.5 2.4 1.4 1.5 1.6 1.4 1.8 1.6 1.9 1.2 1.7 2.1 1.5 1.1 2.5 2.0 1.6 2.1 3.4 1.9 1.8 1.9 1.5 1.6 1.8 1.3 2.4 1.1 1.6 1.7 2.0 1.1 2.5 0.1 2.2\nGlaucoma (self-reported) 1.2 1.4 3.4 1.0 1.3 1.1 0.9 1.1 1.3 1.1 1.7 1.6 1.4 0.7 1.0 1.1 1.0 1.2 1.4 1.3 1.2 0.9 1.1 1.0 1.5 -0.5 0.8 1.1 1.2 1.2 0.8 1.1 0.9 1.0 1.2 0.8 0.6 1.0 0.7 1.4 1.3 1.5 1.5 1.2 1.4 1.0 1.1 1.0 1.3 1.2 1.0 1.4 1.6 1.9 1.0 0.6\nGout (self-reported) 0.3 0.4 1.9 0.3 0.8 0.5 1.3 0.6 0.6 0.6 -0.8 0.4 0.3 0.3 0.4 0.4 0.6 0.4 0.4 0.8 0.8 1.4 0.7 0.2 0.6 0.4 0.2 1.2 0.6 0.9 0.2 0.6 0.6 0.3 0.3 0.3 0.1 0.7 0.4 0.7 0.9 0.6 0.8 0.5 0.5 0.4 0.4 0.8 1.0 0.4 0.7 0.0 0.1 0.1 0.9 1.1\nHypothyroidism/myxoedema (self-reported) 2.2 4.3 9.7 -2.2 -2.3 -2.0 -1.9 -2.0 -2.3 -2.1 -1.5 -2.4 -1.9 -1.9 -2.1 -2.0 -2.2 -2.2 -1.7 -1.9 -2.1 -1.9 -2.7 -1.9 -2.0 -3.1 -1.6 -2.6 -2.3 -2.0 -2.0 -2.2 -2.0 -2.0 -1.7 -1.8 -1.4 -2.4 -2.3 -2.4 -2.2 -2.1 -2.1 -1.8 -2.1 -2.0 -2.0 -2.1 -1.7 -1.8 -2.0 -2.7 -1.9 -2.2 -1.4 -1.7\nMedication: Amlodipine 2.7 3.8 7.4 -2.2 -1.6 -1.9 -1.8 -1.7 -1.6 -2.2 -1.1 -1.8 -2.5 -1.5 -1.9 -2.1 -0.4 -1.6 -2.1 -1.6 -1.9 -1.9 -2.4 -2.2 -2.1 -0.8 -1.3 -2.5 -1.9 -2.4 -1.8 -2.4 -2.3 -2.2 -1.4 -2.5 -1.5 -2.0 -2.1 -2.7 -1.9 -1.6 -2.4 -1.9 -2.6 -2.3 -2.0 -2.3 -1.1 -1.1 -2.3 -2.0 -1.4 -1.9 -0.4 -2.7\nMedication: Ventolin 100micrograms inhaler 1.1 1.4 5.0 -0.9 -0.9 -1.0 -1.3 -1.0 -0.8 -1.0 -0.1 -0.5 -1.1 -1.3 -1.1 -0.9 -0.8 -0.8 -0.9 -0.7 -1.7 -1.8 -1.3 -0.6 -1.2 -0.7 -0.7 -1.9 -1.1 -1.4 -0.7 -1.4 -1.6 -0.9 -0.8 -1.7 -0.7 -0.8 -1.7 -2.2 -1.1 -1.6 -1.5 -1.0 -1.2 -1.3 -1.0 -1.7 -1.3 -1.1 -1.4 -0.8 -0.1 -1.4 -0.9 -1.6\nBirth weight 0.9 2.0 9.6 -1.1 -1.6 -1.1 -1.1 -1.8 -1.9 -1.0 -0.7 -1.9 -1.0 -2.3 -1.3 -1.3 -3.1 -1.8 -0.8 -1.5 -1.3 -0.7 -0.9 -1.2 -1.4 -2.1 -2.6 -1.1 -1.4 -0.8 -1.6 -0.6 -0.9 -1.1 -2.1 -0.9 -2.2 -0.7 -1.2 0.2 -1.0 -1.6 -0.2 -1.9 -0.6 -1.0 -1.3 -1.0 -1.3 -1.5 -0.9 0.2 -1.7 -0.2 -1.9 -0.6\nChronic bronchitis/emphysema (mother) 0.5 0.6 1.8 -0.5 -0.7 -0.9 -0.3 -0.8 -0.7 -0.7 0.1 -1.3 -0.3 -0.6 -0.6 -0.5 -0.1 -0.7 -1.1 -1.2 -0.8 -0.4 -1.0 -0.4 -0.8 -0.8 -0.7 -1.0 -0.9 -0.5 -0.4 -0.9 -0.8 -0.5 -0.4 -0.6 -0.6 -0.5 -0.3 -1.2 -0.9 -1.2 -0.8 -0.6 -1.0 -0.7 -0.6 -0.9 -0.7 -1.0 -0.6 -0.8 -1.3 -0.7 -1.0 -0.7\nHigh blood pressure (siblings) 2.7 4.0 10.4 -2.2 -2.0 -1.7 -2.2 -1.8 -1.6 -2.1 -1.0 -2.4 -2.5 -1.8 -2.3 -2.3 -0.5 -2.2 -1.9 -1.6 -2.1 -2.2 -2.3 -2.4 -1.9 -1.6 -1.0 -2.4 -1.5 -2.4 -2.2 -2.3 -1.7 -2.3 -1.3 -1.4 -0.6 -1.8 -2.0 -2.8 -1.8 -1.6 -2.9 -1.9 -2.3 -2.2 -2.1 -1.4 -1.2 -0.0 -2.4 -3.0 -1.4 -3.2 -0.6 -2.1\nForced vital capacity (FVC), Best measure 0.2 0.6 3.6 -0.5 -0.6 -0.8 -0.9 -1.0 -0.9 -0.4 0.5 -1.2 -0.5 -1.4 -1.0 -0.8 -1.9 -0.9 -0.3 -0.8 -0.9 -0.5 0.1 -0.7 -0.7 -1.2 -1.9 -0.2 -0.5 -0.1 -1.1 -0.3 -0.4 -0.6 -0.8 -0.0 -0.4 -0.6 -0.5 -0.1 -0.3 -0.2 -0.5 -1.1 -0.3 -0.5 -0.8 -0.7 -0.7 -0.1 -0.7 -0.7 0.5 -0.5 -1.6 -0.6\nBody fat percentage 3.5 13.7 25.7 -3.9 -3.7 -3.4 -3.3 -3.8 -3.1 -3.7 -2.4 -3.9 -4.0 -4.0 -4.2 -4.0 -2.9 -4.1 -3.6 -3.2 -4.5 -3.5 -3.4 -3.9 -4.0 -2.9 -3.5 -4.0 -3.2 -3.6 -3.8 -3.8 -3.6 -4.0 -3.2 -3.2 -2.5 -2.9 -3.1 -4.6 -4.3 -4.5 -4.6 -3.8 -4.0 -3.9 -3.9 -2.9 -4.0 -2.1 -4.2 -3.3 -4.3 -5.1 -2.5 -3.6\nLeg fat percentage (right) 3.9 14.1 23.3 -4.0 -3.7 -3.3 -3.4 -3.9 -3.2 -3.7 -2.2 -4.0 -4.2 -4.1 -4.4 -4.1 -2.7 -4.1 -3.6 -3.4 -4.6 -3.5 -3.5 -4.0 -4.0 -3.1 -3.5 -4.4 -3.4 -3.8 -3.9 -3.9 -3.6 -4.1 -3.4 -3.3 -2.5 -2.8 -3.3 -4.6 -4.3 -4.6 -4.5 -4.0 -4.1 -3.9 -4.0 -3.0 -3.9 -2.2 -4.3 -3.2 -4.3 -4.8 -2.5 -3.6\nArm fat-free mass (right) 0.1 0.7 5.1 -0.7 -1.1 -0.4 -0.6 -0.8 -0.7 -1.0 -2.3 -0.5 -0.8 -1.1 -0.9 -1.1 -1.7 -1.1 0.4 -0.0 -0.7 -1.0 0.4 -1.1 -0.9 -1.4 -0.9 -1.0 -0.1 -0.1 -1.4 -0.8 -0.4 -1.0 -1.1 0.3 0.1 0.1 -0.2 1.5 -0.2 0.1 -0.2 -0.9 -0.2 -0.8 -1.0 0.4 -0.2 1.2 -0.9 0.5 0.1 -0.2 -0.9 -0.8\nExposure to tobacco smoke outside home 0.2 0.3 1.4 0.6 0.4 0.2 0.4 0.4 0.5 0.2 -0.4 0.7 0.2 0.4 0.6 0.4 0.7 0.3 0.9 0.3 0.5 0.2 0.4 0.5 0.6 0.9 0.6 1.2 0.6 0.3 0.9 0.3 0.5 0.5 0.5 0.8 0.6 0.5 0.8 0.7 0.8 0.8 0.1 0.5 0.2 0.5 0.4 0.7 0.5 0.8 0.4 -0.2 -0.1 -0.6 0.3 0.6\nComparative body size at age 10 2.5 7.0 12.4 -2.9 -2.9 -2.4 -2.3 -2.9 -2.2 -2.5 -0.7 -3.2 -2.8 -3.3 -3.2 -3.0 -2.7 -3.1 -2.6 -2.1 -3.3 -2.1 -2.5 -3.0 -2.5 -2.8 -2.6 -2.9 -2.6 -2.3 -3.0 -2.2 -2.4 -3.0 -2.6 -2.2 -1.7 -2.2 -2.1 -2.9 -2.6 -3.0 -3.0 -2.9 -2.9 -2.7 -2.9 -2.0 -3.0 -1.8 -2.8 -2.2 -2.9 -3.5 -2.0 -2.1\nNumber of full brothers 1.9 2.4 7.2 -1.6 -1.8 -1.4 -1.3 -1.3 -2.0 -2.0 -1.4 -1.5 -1.4 -0.7 -1.4 -1.4 -1.4 -1.6 -1.5 -1.1 -1.3 -1.7 -2.3 -1.5 -1.5 -1.7 -0.5 -1.7 -1.6 -1.9 -1.4 -2.0 -1.4 -1.6 -0.9 -1.1 -0.5 -1.7 -1.5 -2.3 -1.6 -1.6 -2.0 -1.1 -1.9 -1.6 -1.4 -1.3 -0.2 -0.7 -1.6 -2.7 -1.6 -1.9 -0.5 -1.7\nWorry too long after embarrassment 1.1 1.8 5.0 -2.0 -0.8 -0.9 -1.0 -1.3 -0.8 -0.9 0.0 -1.7 -2.0 -1.6 -1.8 -1.9 -0.7 -0.9 -1.8 -1.2 -1.4 -0.4 -1.1 -2.1 -1.0 -1.0 -1.7 -1.1 -1.3 -1.0 -2.2 -0.9 -1.4 -2.0 -1.4 -2.1 -0.8 -1.1 -1.5 -0.6 -0.4 -0.7 -0.8 -1.9 -1.6 -1.6 -1.8 -1.5 -1.0 -1.4 -1.6 -0.2 -0.0 -0.6 0.2 -1.4\nSeen a psychiatrist for nerves, anxiety, tension or depression 1.1 1.5 4.4 -1.2 -1.4 -1.0 -0.8 -1.3 -1.0 -0.9 -0.7 -1.2 -1.1 -1.6 -1.2 -1.2 -1.8 -1.4 -1.0 -1.6 -1.1 -0.4 -1.3 -1.2 -1.0 -1.3 -1.8 -0.9 -1.6 -0.9 -1.3 -0.6 -1.3 -1.1 -1.7 -1.7 -1.9 -1.3 -1.4 -0.7 -0.8 -1.0 -0.5 -1.5 -0.8 -1.1 -1.1 -1.6 -1.2 -2.1 -0.8 -0.4 -0.2 -0.4 -1.1 -0.8\nWheeze or whistling in the chest in last year 0.5 0.9 4.4 -0.8 -0.3 -0.8 -0.5 -0.6 -0.4 -0.9 -0.6 -0.1 -1.1 -0.6 -0.7 -0.7 0.7 -0.4 -0.9 -0.3 -1.0 -1.0 -1.3 -0.6 -1.0 0.6 -0.2 -1.5 -0.8 -1.2 -0.6 -1.3 -1.2 -0.7 -0.3 -1.5 -0.7 -0.9 -1.4 -2.1 -1.0 -1.1 -1.3 -0.6 -1.3 -1.1 -0.7 -1.5 -0.6 -0.7 -1.1 -1.2 -0.3 -0.7 -0.3 -1.4\nNumber of children fathered 0.2 0.2 0.8 0.6 0.7 -0.0 -0.8 0.2 0.2 0.2 -0.4 0.4 0.4 0.4 0.5 0.4 0.6 0.4 -0.1 -0.4 0.0 -0.9 0.2 0.6 -0.2 0.4 0.2 -0.9 0.1 -0.5 0.8 -0.4 -0.1 0.7 0.3 0.0 0.6 -0.2 -0.2 -0.1 -0.4 -0.1 -0.2 0.3 0.3 0.3 0.4 -0.2 0.1 -0.2 -0.0 0.1 -0.3 0.4 -0.6 -0.6\nReason for reducing amount of alcohol drunk: Health precaution 2.3 2.7 4.6 1.9 1.6 1.2 1.2 1.4 1.6 1.8 1.8 1.5 1.7 1.3 1.7 1.7 2.0 1.7 1.8 1.2 1.8 1.5 2.0 1.7 1.6 1.9 1.3 1.5 1.4 1.7 1.8 1.7 1.7 1.8 1.5 2.0 1.3 1.6 1.9 2.1 1.5 1.8 1.5 1.4 1.9 1.8 1.6 1.3 1.1 1.1 1.8 1.7 2.0 1.7 0.4 1.3\nAge at first live birth 0.4 0.6 2.0 0.7 0.7 0.8 0.4 0.8 0.8 0.9 0.5 0.9 0.9 0.5 0.7 0.8 0.4 0.7 1.0 0.6 1.0 0.8 1.3 0.7 0.9 0.2 0.2 1.2 0.9 0.9 0.7 1.1 0.8 0.7 0.5 0.7 0.2 0.5 0.8 1.4 0.6 1.1 1.1 0.6 1.1 0.8 0.8 0.7 0.6 0.3 0.8 0.8 1.1 1.1 0.5 0.6\nPulse wave peak to peak time 0.2 0.3 1.1 0.6 0.6 0.3 0.4 0.3 0.3 0.7 0.7 0.2 0.8 0.4 0.7 0.6 0.5 0.3 0.2 -0.1 0.5 0.5 0.5 0.7 0.5 1.0 -0.0 0.2 0.4 0.5 0.5 0.5 0.5 0.7 0.2 0.2 -0.0 0.0 0.1 0.8 0.6 0.4 0.9 0.3 0.7 0.6 0.6 0.0 0.3 -0.2 0.6 0.6 0.0 1.1 -0.2 0.4\nHealth satisfaction 0.2 0.3 1.4 -0.2 -0.3 -0.3 -0.6 -0.4 -0.3 -0.2 0.2 0.4 -0.0 -0.5 -0.2 -0.3 0.2 -0.0 -0.6 -0.4 -0.6 -0.5 -0.7 -0.3 -0.4 -0.2 -0.5 -0.6 -0.6 -0.5 0.2 -0.2 -0.7 -0.1 -0.5 -1.0 -0.9 -0.2 -0.7 -1.2 -0.8 -1.1 -0.3 -0.4 -0.3 -0.4 -0.1 -0.8 -0.9 -0.8 -0.4 0.1 -0.9 -0.2 -0.6 -0.4\nShortness of breath walking on level ground 2.2 2.6 6.5 -1.6 -1.5 -1.6 -1.6 -1.6 -1.2 -2.0 -1.1 -1.0 -1.4 -1.2 -1.4 -1.6 -0.2 -1.1 -1.3 -1.1 -1.8 -2.3 -2.2 -1.6 -1.6 -1.1 -0.5 -2.5 -1.5 -2.0 -1.3 -2.2 -2.1 -1.6 -0.9 -1.9 -0.6 -1.5 -1.8 -2.0 -2.0 -1.9 -1.9 -1.1 -1.9 -2.0 -1.5 -1.5 -1.7 -0.7 -2.1 -1.3 -1.8 -1.7 -1.0 -2.2\nQualifications: College or University degree 0.1 0.4 2.2 0.9 0.4 0.3 -0.8 0.3 0.6 0.7 1.3 0.3 0.4 0.5 0.6 0.7 0.8 0.5 0.8 0.1 0.1 -0.6 0.8 1.0 0.5 -0.1 1.0 -0.2 0.5 0.3 0.6 0.5 0.8 0.8 0.4 1.5 1.1 0.4 0.8 1.0 0.1 0.6 -0.1 0.3 0.5 0.8 0.5 0.7 -0.5 0.9 0.1 0.7 -0.1 0.6 -0.9 0.1\nEye problems/disorders: None of the above 0.1 0.1 0.6 -0.2 0.2 -0.0 -0.4 -0.1 0.1 -0.3 -0.8 -0.2 -0.5 0.2 -0.0 -0.2 0.1 0.0 0.0 0.4 -0.3 -0.7 -0.4 -0.2 -0.1 0.4 0.1 -0.6 0.2 -0.5 0.1 -0.5 -0.5 -0.2 0.1 -0.5 0.3 -0.1 -0.7 -0.7 -0.2 -0.4 -0.5 -0.0 -0.4 -0.4 -0.2 -0.3 -0.0 0.7 -0.5 0.0 -0.1 -0.3 0.5 -0.5\nMouth/teeth dental problems: Loose teeth 0.2 0.2 1.6 0.3 -0.0 0.3 0.7 0.2 0.2 0.5 -0.4 0.1 0.3 -0.0 0.3 0.2 0.1 -0.1 0.7 0.3 0.3 0.6 0.2 0.1 0.4 0.1 -0.1 0.9 0.3 0.6 0.2 0.6 0.5 0.2 -0.2 0.6 0.2 0.2 0.6 1.3 0.7 0.6 0.7 0.1 0.4 0.4 0.2 0.6 0.1 0.4 0.5 0.7 -0.1 0.4 -0.2 0.8\nEmphysema/chronic bronchitis 0.1 0.1 0.6 -0.4 -0.2 0.1 0.1 -0.0 -0.1 -0.4 0.0 -0.3 -0.4 0.1 -0.2 -0.3 0.1 -0.4 -0.2 0.8 -0.2 -0.4 -0.4 -0.4 0.2 -0.6 0.4 -0.5 0.1 -0.4 -0.2 -0.5 -0.1 -0.4 0.1 -0.1 0.4 0.1 -0.4 -0.1 -0.3 -0.2 -0.3 -0.2 -0.2 -0.3 -0.2 0.1 0.4 0.8 -0.4 0.2 -0.3 -0.1 0.5 -0.8\nMedication for pain relief, constipation, heartburn 1.8 3.1 10.6 1.5 1.6 1.3 1.7 1.4 1.7 1.8 2.0 1.5 1.1 1.2 1.5 1.3 1.8 1.3 1.8 1.4 1.9 2.0 2.3 1.2 1.8 2.6 1.1 2.5 1.7 2.0 1.2 1.7 2.2 1.3 1.5 2.6 2.4 1.3 2.3 3.3 2.0 2.4 1.5 1.1 1.7 1.8 1.1 2.5 1.4 1.7 1.7 1.2 0.6 1.4 0.2 2.0\nNeck or shoulder pain in last month 0.2 0.2 1.9 0.3 -0.1 -0.2 -0.7 -0.2 -0.1 0.2 1.1 -0.0 0.5 -0.6 -0.0 0.2 -0.7 -0.0 -0.3 -0.2 -0.7 -0.7 -0.2 0.4 -0.0 -1.4 -0.5 -0.9 -0.1 -0.2 0.3 0.0 -0.1 0.4 0.1 -0.1 -0.4 0.3 -0.0 -0.8 -0.7 -1.0 -0.3 0.1 0.0 0.0 0.2 -0.4 -0.8 -0.5 -0.2 0.5 -0.8 -0.3 -0.4 -0.5\nMedication: Blood pressure 1.0 1.7 7.1 -1.3 -0.9 -0.9 -0.6 -1.0 -1.0 -0.8 -1.2 -1.0 -1.1 -1.4 -1.3 -1.1 -1.5 -1.3 -1.2 -1.6 -1.3 -0.5 -1.5 -1.1 -1.1 -1.1 -1.8 -0.8 -1.1 -1.1 -1.1 -0.9 -1.5 -1.1 -1.2 -2.2 -2.1 -1.2 -1.6 -2.7 -1.3 -1.4 -1.1 -1.4 -1.1 -1.3 -1.0 -2.0 -0.8 -1.5 -1.1 -1.2 -0.9 -1.6 0.1 -1.4\nAngina (self-reported) 0.5 0.6 5.0 -0.3 -0.7 -0.9 -0.7 -0.4 0.0 -0.8 0.5 -0.7 -0.8 -0.4 -0.6 -0.4 -0.3 -0.2 -0.4 -0.5 -1.0 -0.9 -0.9 -0.3 -0.8 -0.3 0.5 -2.2 -0.5 -0.5 -0.5 -1.0 -0.8 -0.5 -0.2 -0.1 -0.3 0.0 0.0 -1.5 -0.9 -1.0 -1.5 -0.3 -1.0 -0.7 -0.6 -0.1 -1.1 0.5 -1.0 -0.2 -1.5 -1.5 -0.4 -0.8\nMigraine (self-reported) 0.3 0.4 1.1 -0.6 -0.6 -0.6 -1.0 -0.8 -1.0 -0.5 -0.4 -0.3 -0.6 -0.7 -0.5 -0.6 -0.2 -0.3 -0.4 -0.8 -0.8 -1.0 -0.4 -0.5 -0.6 -0.5 -0.5 -0.8 -0.7 -0.8 -0.4 -0.5 -0.5 -0.5 -0.8 -0.4 -0.3 -0.6 -0.8 0.2 -0.5 -0.7 -0.2 -0.8 -0.5 -0.5 -0.7 -0.9 -0.8 -0.7 -0.7 -0.0 -0.5 0.2 -0.8 -0.8\nMedication: Ibuprofen 0.8 1.0 3.9 -0.8 -1.3 -0.9 -1.2 -0.9 -0.9 -1.2 -1.4 -1.2 -0.7 -0.5 -0.6 -0.8 -1.3 -0.6 -0.8 -0.9 -0.7 -1.5 -1.4 -0.9 -1.0 -0.7 0.1 -2.0 -1.2 -1.3 -0.6 -1.2 -1.3 -0.7 -0.9 -1.2 -0.6 -1.4 -1.4 -0.8 -0.9 -0.6 -0.8 -0.6 -0.8 -1.1 -0.7 -1.4 -0.7 -1.1 -1.0 -0.9 0.5 -0.4 -0.5 -1.3\nMedication: Allopurinol 0.6 0.7 2.3 0.8 1.1 0.8 1.5 1.0 0.7 1.0 -0.3 1.1 0.9 0.6 0.9 0.9 0.7 0.8 0.6 1.0 0.9 1.3 0.8 0.9 1.0 0.5 0.7 1.1 0.8 1.1 0.8 0.7 0.8 0.9 0.7 0.4 0.4 0.9 0.4 0.5 1.0 0.4 1.1 1.0 0.9 0.9 0.9 0.8 1.1 0.4 1.0 0.5 0.0 0.6 0.8 1.2\nMedication: Omeprazole 0.8 0.9 2.2 -1.1 -0.9 -0.7 -1.0 -0.9 -0.9 -0.6 0.2 -1.1 -1.1 -1.0 -1.2 -1.0 -1.1 -0.8 -1.3 -1.0 -1.1 -0.6 -0.9 -1.0 -1.0 -1.3 -1.4 -1.2 -1.0 -0.9 -1.1 -0.6 -0.9 -1.1 -1.0 -1.2 -1.5 -0.7 -1.0 -1.3 -1.0 -1.0 -0.8 -1.1 -0.9 -1.0 -1.0 -1.0 -1.0 -0.9 -1.0 -0.6 -0.3 -0.7 0.0 -0.9\nMedication: Seretide 50 evohaler 0.6 0.7 2.1 -0.5 -0.8 -0.9 -0.8 -0.7 -0.4 -0.6 0.4 -0.5 -0.5 -0.9 -0.7 -0.6 -0.2 -0.7 -0.9 -0.8 -1.2 -1.0 -0.9 -0.4 -0.7 -1.1 -0.8 -1.3 -0.7 -0.8 -0.5 -0.7 -1.1 -0.5 -0.6 -1.0 -0.8 -0.5 -0.6 -1.4 -1.1 -1.2 -0.9 -0.7 -0.9 -0.9 -0.6 -1.1 -1.4 -0.7 -0.9 0.1 -1.0 -0.5 -1.4 -1.1\nMean time to correctly identify matches 0.2 0.4 2.6 -0.4 -0.2 -0.1 0.3 -0.5 -0.5 0.1 -0.5 -0.1 -0.4 -0.6 -0.3 -0.3 -0.1 -0.2 -0.5 -0.8 -0.4 0.7 -0.8 -0.2 -0.6 -0.6 -0.7 -0.3 -1.0 -0.2 -0.3 0.2 -0.4 -0.2 -1.0 -1.2 -1.6 -0.1 -0.8 -0.5 -0.4 -1.2 0.4 -0.7 -0.2 -0.1 -0.3 -0.8 -0.6 -1.6 0.0 0.7 -1.0 0.4 -0.2 0.2\nHeart disease (mother) 1.5 1.9 4.5 -1.2 -1.3 -1.4 -1.7 -1.5 -1.0 -1.2 0.3 -2.0 -1.4 -1.6 -1.5 -1.4 -1.2 -1.3 -1.1 -1.8 -1.5 -1.5 -1.1 -1.3 -1.2 -1.4 -1.4 -2.1 -1.2 -1.4 -1.3 -1.3 -1.2 -1.3 -1.2 -0.8 -1.1 -1.2 -1.1 -1.3 -1.7 -1.3 -1.6 -1.5 -1.2 -1.3 -1.4 -1.1 -1.6 -0.7 -1.6 -1.0 -1.4 -1.2 -1.2 -1.7\nReproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.9 -0.5 0.0 0.1 0.2 -0.1 -0.2 -0.3 -0.4 -0.2 -0.0 -0.1 -0.2 -0.3 -0.0 -0.3 -0.1 -0.1 -0.1 0.1 -0.4 -0.4 -0.1 0.6 -0.2 0.1 -0.2 -0.4 -0.5 -0.2 -0.4 -0.3 -0.2 -1.0 -0.2 -0.3 -0.7 -0.7 -0.4 -0.6 -0.0 -0.2 -0.3 -0.3 -0.1 -0.6 -0.0 -0.9 -0.1 -0.6 -0.2 -0.3 0.3 -0.2\nWhole body fat mass 3.2 13.2 21.7 -3.8 -3.9 -3.4 -3.4 -3.8 -3.2 -3.8 -3.0 -3.8 -4.0 -4.1 -4.2 -4.1 -3.4 -4.2 -3.3 -3.0 -4.3 -3.6 -3.2 -4.0 -4.0 -3.2 -3.5 -3.8 -3.1 -3.5 -4.0 -3.8 -3.5 -4.0 -3.4 -2.9 -2.4 -2.8 -3.0 -3.7 -4.1 -4.0 -4.3 -3.9 -3.8 -3.9 -4.0 -2.7 -3.7 -1.7 -4.2 -3.0 -3.8 -4.7 -2.7 -3.7\nLeg fat mass (right) 3.2 12.3 18.8 -3.8 -3.7 -3.2 -3.3 -3.7 -3.1 -3.6 -2.6 -3.7 -4.0 -4.0 -4.1 -4.0 -3.1 -4.0 -3.1 -2.9 -4.2 -3.5 -3.0 -3.9 -3.8 -3.1 -3.4 -3.9 -3.1 -3.4 -3.9 -3.7 -3.4 -3.9 -3.3 -2.8 -2.3 -2.6 -3.0 -3.6 -3.9 -4.0 -4.1 -3.8 -3.7 -3.8 -3.9 -2.6 -3.4 -1.6 -4.1 -2.9 -3.7 -4.3 -2.5 -3.6\nArm predicted mass (right) 0.2 1.2 6.0 -0.9 -1.5 -0.9 -1.0 -1.2 -1.1 -1.3 -2.4 -0.9 -1.1 -1.5 -1.2 -1.3 -2.1 -1.5 0.1 -0.5 -1.0 -1.2 0.1 -1.3 -1.3 -1.7 -1.4 -1.1 -0.5 -0.4 -1.7 -1.0 -0.7 -1.2 -1.6 0.2 -0.4 -0.2 -0.4 1.4 -0.5 -0.2 -0.5 -1.3 -0.5 -1.1 -1.3 0.1 -0.7 0.7 -1.2 0.3 -0.2 -0.4 -1.4 -1.0\nPulse rate, automated reading 0.2 0.8 4.5 0.7 0.9 0.8 0.9 0.8 0.6 0.9 -0.1 1.1 0.9 1.1 0.8 0.9 1.4 1.1 1.3 0.4 0.9 1.0 0.9 0.8 0.5 0.5 0.2 0.3 0.7 0.8 0.8 0.8 0.6 0.8 0.5 0.4 -0.2 1.0 0.4 1.0 0.6 0.4 1.4 0.8 0.9 0.8 0.8 0.5 1.0 0.6 0.8 1.7 0.7 2.1 0.8 0.4\nAlcohol intake frequency. 3.7 8.7 13.2 -3.3 -3.0 -2.7 -2.9 -3.0 -2.9 -3.2 -1.9 -2.7 -3.2 -2.7 -3.2 -3.1 -2.5 -3.0 -3.2 -2.6 -3.1 -2.6 -3.3 -3.2 -3.2 -2.6 -2.3 -3.0 -3.0 -3.2 -3.1 -2.8 -3.0 -3.2 -2.7 -3.1 -2.6 -2.7 -2.7 -3.6 -3.0 -3.2 -3.2 -2.9 -3.5 -3.1 -3.1 -2.7 -2.6 -2.7 -3.2 -3.3 -2.7 -3.2 -1.6 -2.6\nComparative height size at age 10 0.5 2.5 7.8 -1.3 -2.0 -1.9 -1.5 -1.9 -2.4 -1.7 -2.3 -1.7 -1.2 -1.8 -1.5 -1.4 -2.8 -2.2 -1.4 -2.0 -1.2 -1.3 -1.2 -1.3 -1.8 -2.6 -1.7 -0.2 -1.8 -1.2 -1.9 -1.3 -1.4 -1.3 -2.1 -0.8 -2.0 -1.9 -1.3 -0.3 -1.3 -0.9 -1.1 -1.6 -1.1 -1.3 -1.6 -1.4 -1.2 -1.4 -1.1 -1.7 -0.3 -0.9 -2.5 -1.0\nNumber of full sisters 3.2 3.9 8.0 -1.9 -1.6 -2.4 -1.6 -1.6 -1.9 -2.3 -2.2 -1.0 -1.7 -1.2 -1.5 -1.7 -0.9 -1.4 -2.3 -1.8 -1.8 -2.1 -2.6 -1.6 -2.1 -0.7 -1.6 -2.3 -2.0 -2.3 -1.5 -2.5 -2.5 -1.7 -1.4 -2.5 -2.1 -2.5 -2.5 -2.5 -2.3 -2.2 -2.0 -1.4 -2.3 -2.2 -1.7 -2.8 -1.8 -2.4 -2.0 -2.4 -1.0 -1.9 -1.2 -2.3\nSuffer from ‘nerves’ 0.1 0.2 0.9 -0.7 0.1 -0.1 -0.0 -0.3 0.2 -0.1 0.7 -0.2 -0.8 -0.4 -0.5 -0.7 0.9 0.3 -0.4 -0.0 -0.3 0.4 -0.3 -0.9 -0.0 0.8 -0.6 0.3 -0.3 -0.1 -0.6 0.0 -0.1 -0.7 -0.3 -0.6 0.1 -0.4 -0.6 0.3 0.4 -0.1 0.2 -0.7 -0.5 -0.4 -0.6 -0.4 -0.3 -0.4 -0.3 0.8 -0.4 0.4 0.3 -0.3\nOverall health rating 3.5 7.5 15.4 -3.2 -2.2 -2.3 -2.1 -2.5 -2.2 -2.7 -1.9 -2.5 -2.9 -2.9 -2.9 -3.0 -2.2 -2.5 -2.5 -1.9 -2.9 -2.0 -3.3 -3.0 -2.7 -2.1 -3.1 -3.1 -2.5 -2.8 -2.8 -2.5 -3.2 -3.1 -2.7 -3.9 -3.2 -2.4 -3.5 -3.5 -2.7 -3.3 -2.4 -2.9 -2.9 -3.2 -2.8 -3.3 -2.5 -2.3 -2.9 -1.7 -2.4 -2.5 -1.1 -2.9\nChest pain or discomfort 2.1 3.0 7.1 -1.5 -1.3 -1.8 -2.1 -1.6 -1.4 -1.7 -0.9 -1.5 -1.8 -1.7 -1.5 -1.7 -0.5 -1.5 -1.3 -1.6 -1.9 -2.3 -1.9 -1.5 -1.8 -0.8 -1.1 -2.7 -1.5 -2.3 -1.6 -2.1 -1.9 -1.5 -1.4 -1.9 -1.1 -1.7 -2.0 -1.9 -2.1 -1.9 -2.1 -1.7 -1.8 -1.8 -1.6 -1.8 -1.8 -1.2 -2.0 -1.7 -1.5 -2.0 -1.5 -2.2\nHad major operations 0.4 0.4 3.8 -0.1 -0.6 -0.4 -0.7 -0.4 -0.4 -0.5 -0.2 -0.2 -0.3 -0.6 -0.4 -0.3 -1.0 -0.7 -0.4 -0.3 -0.7 -0.6 -0.8 -0.3 -0.3 -1.3 -0.1 -1.2 -0.4 -0.5 -0.4 -0.3 -0.4 -0.2 -0.4 -0.3 -0.6 -0.2 -0.1 -1.3 -0.8 -0.8 -1.0 -0.4 -0.3 -0.4 -0.3 -0.2 -1.0 -0.0 -0.4 -0.3 -1.3 -1.9 -0.4 -0.3\nAge at last live birth 1.1 1.6 3.1 1.3 1.1 1.2 0.9 1.3 1.6 1.6 0.4 1.6 1.5 1.1 1.3 1.4 0.9 1.2 1.4 0.9 1.5 1.4 1.7 1.3 1.1 1.0 0.5 1.3 1.5 1.4 1.3 1.7 1.2 1.4 0.9 1.0 -0.1 1.3 1.5 1.5 1.0 1.4 1.6 1.1 1.6 1.3 1.4 1.0 0.8 0.6 1.4 1.6 1.7 1.3 1.0 1.2\nFamily relationship satisfaction 0.2 0.3 2.8 0.7 0.2 0.3 0.3 0.4 0.1 0.4 0.4 1.1 0.7 0.3 0.6 0.6 0.1 0.3 0.0 0.4 0.2 0.2 0.3 0.7 0.2 0.9 0.6 -0.0 0.3 0.4 0.5 0.4 0.5 0.8 0.3 0.6 0.1 0.6 0.5 -0.3 0.0 -0.4 0.2 0.5 0.4 0.5 0.6 0.5 0.1 0.1 0.5 0.4 -1.7 -0.0 -0.3 0.7\nLeg pain on walking 5.5 6.9 13.9 -2.5 -2.8 -2.8 -2.1 -3.0 -2.7 -2.5 -1.1 -3.1 -2.0 -2.7 -2.7 -2.5 -2.0 -2.5 -2.6 -3.0 -2.9 -2.0 -2.9 -2.4 -2.6 -3.7 -2.5 -3.5 -3.2 -2.2 -2.4 -2.5 -2.6 -2.4 -2.7 -2.4 -2.3 -2.6 -2.3 -2.5 -2.9 -3.1 -2.2 -2.5 -2.5 -2.5 -2.5 -2.7 -3.0 -3.2 -2.5 -2.3 -2.5 -2.0 -3.2 -2.2\nQualifications: NVQ or HND or HNC or equivalent 1.8 2.1 9.9 -1.3 -1.5 -1.2 -0.4 -1.6 -1.9 -1.1 -1.4 -0.9 -0.8 -1.6 -1.0 -1.2 -2.2 -1.4 -1.8 -1.6 -1.1 -0.1 -1.9 -1.2 -1.1 -1.4 -2.7 -0.5 -2.0 -0.8 -1.4 -0.5 -1.4 -1.0 -1.9 -2.3 -2.6 -1.6 -1.7 -0.9 -0.9 -1.4 0.1 -1.6 -0.9 -1.2 -1.1 -2.4 -1.2 -3.1 -0.5 -0.5 -0.5 0.2 -1.6 -0.6\nCommuting to job workplace: Car/motor vehicle 0.6 0.7 2.4 0.6 0.7 1.0 1.0 0.9 0.8 0.8 1.5 0.8 0.7 1.0 0.7 0.7 0.9 1.0 0.8 0.8 0.9 0.8 0.7 0.5 0.8 0.3 0.4 0.4 0.8 0.9 0.8 0.7 0.9 0.6 1.0 0.7 0.8 0.6 0.5 0.4 0.8 1.1 0.9 0.7 0.9 0.7 0.8 0.5 1.5 0.8 0.7 0.6 1.1 1.2 1.4 0.0\nIllness, injury, bereavement, stress in last 2 years 3.9 4.8 7.7 2.6 2.1 2.1 2.1 2.0 1.8 2.1 2.7 1.9 2.1 2.2 2.1 2.3 1.6 2.0 2.2 1.8 2.2 2.1 2.7 2.3 2.1 1.6 1.8 2.4 2.1 2.5 2.3 2.1 2.6 2.4 2.1 2.8 2.5 2.5 2.6 2.2 2.4 2.2 1.9 2.1 2.2 2.6 2.2 2.6 2.2 2.1 2.3 1.7 1.3 1.9 1.1 2.5\nMedication: Aspirin 0.7 0.9 3.9 -0.5 -0.6 -0.7 -0.9 -0.6 -0.6 -0.7 -1.2 -0.5 -0.5 -0.7 -0.7 -0.5 -0.6 -0.4 -0.8 -1.1 -1.2 -0.9 -1.2 -0.3 -1.0 -1.4 -0.6 -1.9 -0.9 -1.0 -0.4 -0.9 -1.2 -0.4 -0.8 -1.4 -1.6 -0.1 -1.0 -2.0 -1.2 -1.8 -0.8 -0.6 -0.8 -0.8 -0.5 -1.1 -1.0 -0.7 -0.9 0.1 -1.6 -0.8 -0.6 -1.0\nSupplements: Vitamin C 0.2 0.3 2.5 0.4 0.4 0.4 -0.1 0.6 0.3 0.1 0.6 0.9 0.1 0.7 0.6 0.5 0.3 0.6 0.5 0.3 0.7 -0.2 0.4 0.6 0.3 0.6 0.4 0.9 0.5 -0.0 0.6 0.1 0.2 0.5 0.6 0.1 0.4 0.0 0.1 0.2 0.4 0.7 0.2 0.4 0.3 0.3 0.4 -0.3 0.9 0.1 0.3 -0.1 1.6 0.7 0.5 -0.2\nKnee pain experienced in last month 2.3 3.6 7.5 -1.6 -1.9 -2.1 -1.3 -1.9 -1.8 -1.6 -1.3 -1.5 -1.5 -2.0 -1.8 -1.6 -1.8 -1.8 -1.9 -2.0 -2.1 -1.2 -2.0 -1.5 -2.1 -1.7 -2.1 -2.0 -2.2 -1.6 -1.5 -1.7 -2.1 -1.5 -2.1 -2.1 -2.7 -1.9 -1.9 -2.3 -2.7 -2.6 -1.7 -1.8 -1.9 -1.8 -1.7 -2.2 -2.4 -2.5 -1.7 -1.4 -2.1 -1.2 -2.1 -1.8\nHypertension (Self-reported) 3.6 10.0 26.2 -3.3 -2.3 -3.0 -2.2 -2.8 -2.6 -2.9 -1.3 -2.8 -3.3 -3.1 -3.2 -3.0 -2.1 -2.7 -3.5 -3.0 -3.2 -2.5 -4.0 -2.9 -3.0 -3.0 -3.2 -3.2 -3.2 -3.3 -2.6 -3.4 -3.7 -3.1 -2.4 -4.5 -3.6 -3.4 -4.3 -5.1 -3.1 -3.1 -3.2 -3.1 -3.3 -3.5 -3.0 -4.5 -2.2 -3.2 -3.3 -3.5 -1.3 -3.0 -1.2 -3.9\nGastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.1 3.2 -1.4 -0.8 -0.9 -0.7 -0.8 -0.7 -1.0 -1.6 -1.2 -1.2 -1.1 -1.2 -1.2 -0.9 -0.8 -0.4 -0.6 -0.9 -0.7 -1.2 -1.3 -0.8 -1.3 -1.3 -1.4 -0.9 -0.8 -1.3 -1.1 -1.3 -1.4 -1.0 -1.5 -1.6 -0.9 -1.8 -0.6 -0.9 -0.6 -0.6 -1.2 -0.8 -1.5 -1.1 -1.2 -1.0 -0.2 -1.2 -0.1 0.2 -0.7 0.1 -1.6\nIllnesses of father: Heart disease 0.2 0.3 2.2 -0.1 -0.4 -0.1 0.0 -0.1 0.4 0.0 1.5 0.3 -0.3 -0.2 -0.2 -0.0 0.6 0.1 -0.5 -0.3 -0.7 -0.1 -0.7 0.2 -0.0 -0.1 0.4 -1.0 -0.4 -0.0 0.1 -0.1 -0.4 0.0 0.1 -0.5 -0.0 0.1 0.0 -1.4 -0.6 -0.8 -0.6 -0.3 -0.6 -0.2 -0.1 -0.5 -1.0 -0.6 -0.4 0.3 -1.3 -1.0 0.2 -0.4\nIllnesses of siblings: Diabetes 1.3 1.6 3.8 -1.2 -1.5 -1.4 -1.4 -1.5 -1.5 -1.0 -0.6 -1.2 -1.3 -1.9 -1.4 -1.3 -1.5 -1.6 -1.4 -1.3 -1.2 -0.8 -1.4 -1.2 -1.3 -1.6 -1.6 -0.3 -1.3 -1.1 -1.5 -0.7 -0.9 -1.2 -1.5 -0.7 -1.5 -1.1 -1.0 -0.8 -1.1 -1.1 -1.3 -1.5 -1.0 -1.1 -1.3 -0.9 -1.6 -1.0 -1.1 -1.3 -1.6 -1.6 -1.4 -0.4\nSmoking status: Previous 0.5 0.8 5.7 -1.3 -0.8 -0.6 -0.3 -0.8 -0.4 -0.6 -2.4 -1.4 -1.0 -0.8 -1.0 -1.1 -0.1 -0.6 -0.3 -0.7 -0.7 -0.2 -0.9 -1.3 -0.9 -0.9 -1.1 -1.5 -0.7 -0.6 -1.1 -0.5 -1.0 -1.3 -0.8 -1.3 -1.1 -0.4 -0.6 -0.2 -0.4 -0.5 -0.3 -0.8 -0.9 -1.1 -1.0 -0.9 -0.6 -0.4 -0.9 0.1 0.1 -0.6 0.4 -0.7\nForced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 4.3 -0.0 -1.1 -0.8 -0.2 -0.7 -1.1 -0.7 -0.6 -0.8 0.3 -0.6 -0.1 -0.1 -2.1 -1.0 0.1 -0.8 -0.1 -0.3 -0.2 -0.1 -0.5 -1.1 -0.7 0.6 -0.6 0.0 -0.3 -0.2 -0.3 0.0 -0.7 0.5 -0.7 -1.0 -0.1 0.5 -0.4 0.2 0.0 -0.2 0.2 -0.2 -0.2 -0.2 -0.3 -0.4 0.1 -0.8 0.2 0.2 -1.8 -0.0\nWhole body fat-free mass 0.2 1.3 8.5 -1.0 -1.5 -0.9 -1.2 -1.1 -1.1 -1.4 -2.9 -0.8 -1.0 -1.5 -1.2 -1.4 -2.1 -1.6 0.1 -0.3 -1.0 -1.5 0.1 -1.4 -1.2 -1.6 -1.2 -1.1 -0.4 -0.6 -1.7 -1.2 -0.8 -1.3 -1.5 0.1 -0.3 -0.3 -0.5 1.3 -0.5 -0.1 -0.6 -1.2 -0.5 -1.2 -1.3 0.1 -0.6 1.1 -1.3 0.2 0.0 -0.7 -1.3 -1.2\nLeg fat-free mass (right) 0.2 0.8 5.3 -0.8 -1.1 -0.7 -1.0 -0.8 -0.6 -1.1 -2.3 -0.4 -0.9 -1.2 -1.0 -1.2 -1.6 -1.2 0.0 0.1 -0.8 -1.2 0.3 -1.3 -0.9 -0.8 -0.9 -0.6 -0.0 -0.3 -1.5 -0.9 -0.6 -1.2 -1.0 0.3 0.1 -0.1 -0.1 1.2 -0.3 0.2 -0.6 -1.0 -0.5 -1.1 -1.1 0.4 -0.5 1.4 -1.1 0.2 0.1 -0.8 -0.8 -1.0\nArm fat percentage (left) 3.1 12.3 22.6 -3.8 -3.4 -3.2 -3.1 -3.5 -2.8 -3.5 -2.1 -3.5 -3.9 -3.8 -4.1 -3.9 -2.7 -3.8 -3.4 -2.7 -4.2 -3.3 -3.2 -3.9 -3.7 -2.3 -3.5 -3.7 -3.0 -3.4 -3.8 -3.6 -3.5 -3.9 -3.0 -3.3 -2.4 -2.6 -3.1 -4.4 -4.0 -4.2 -4.3 -3.8 -3.9 -3.9 -3.8 -2.8 -3.8 -1.9 -4.1 -2.9 -3.9 -4.7 -2.2 -3.5\nAverage weekly red wine intake 1.1 1.6 4.8 1.7 0.8 0.9 0.2 1.1 1.2 1.3 0.4 1.6 1.2 1.1 1.4 1.4 1.2 1.1 2.2 0.8 1.1 0.1 1.5 1.7 1.3 1.1 2.0 0.7 1.3 1.1 1.5 1.1 1.3 1.6 1.0 2.2 1.7 0.7 1.3 1.8 0.9 1.8 0.6 1.2 1.4 1.3 1.2 1.2 0.0 1.6 1.1 1.1 1.6 0.8 -0.2 0.8\nHandedness (chirality/laterality): Left-handed 0.8 1.0 4.3 0.7 0.9 1.2 0.5 1.2 1.3 0.5 0.3 1.4 0.6 1.4 1.1 0.8 1.1 0.9 0.6 1.5 1.0 0.1 0.5 0.6 0.9 1.8 2.1 0.1 1.2 0.2 1.1 0.5 0.9 0.7 1.3 0.9 1.9 0.6 0.7 0.4 1.0 1.0 0.2 1.2 0.7 0.7 0.9 1.1 1.1 1.5 0.6 0.3 0.3 -0.3 1.9 0.7\nMood swings 1.3 2.4 5.7 -2.0 -1.6 -1.4 -1.5 -1.6 -1.1 -1.3 -0.7 -1.2 -1.8 -2.0 -1.8 -1.9 -1.0 -1.3 -1.7 -1.5 -1.6 -0.8 -1.4 -2.0 -1.4 -1.4 -2.2 -1.1 -1.7 -1.4 -1.8 -0.9 -1.6 -1.9 -1.9 -2.2 -2.2 -1.5 -1.4 -1.2 -1.1 -1.4 -1.0 -1.8 -1.5 -1.7 -1.7 -1.9 -1.9 -2.4 -1.5 -0.6 -0.2 -1.1 -0.6 -1.0\nLoneliness, isolation 1.5 2.1 6.0 -1.8 -1.4 -1.3 -1.6 -1.4 -1.2 -1.4 -0.2 -1.2 -2.0 -1.7 -1.7 -1.8 -1.1 -1.3 -1.1 -1.2 -1.6 -1.2 -1.2 -1.8 -1.4 -0.6 -1.4 -1.3 -1.4 -1.5 -1.9 -1.3 -1.3 -1.9 -1.6 -1.3 -1.1 -1.2 -1.3 -0.8 -1.0 -1.5 -1.2 -1.9 -1.8 -1.6 -1.8 -1.3 -1.3 -1.0 -1.8 -0.5 -2.4 -1.1 -0.9 -1.3\nLong-standing illness, disability or infirmity 1.6 2.5 7.8 -1.9 -0.8 -1.1 -0.6 -1.4 -0.9 -0.9 0.2 -1.7 -1.6 -2.0 -1.9 -1.7 -1.0 -1.1 -2.1 -1.4 -1.6 0.0 -1.6 -1.8 -1.2 -1.6 -2.6 -1.0 -1.5 -1.1 -1.8 -0.7 -1.7 -1.7 -1.6 -2.8 -2.5 -1.2 -2.1 -2.5 -1.4 -1.9 -0.9 -1.8 -1.4 -1.7 -1.5 -2.2 -1.7 -2.4 -1.4 -0.8 -0.8 -1.0 -0.2 -1.2\nEver had bowel cancer screening 0.4 0.5 2.8 -0.8 -0.5 -0.7 0.2 -0.3 -0.3 -0.8 -1.7 -0.6 -0.7 -0.4 -0.6 -0.7 -0.2 -0.4 -0.5 -0.1 -0.6 -0.4 -0.9 -0.8 -0.7 -0.7 -0.4 -1.2 -0.5 -0.3 -0.7 -1.0 -1.1 -0.8 -0.7 -1.2 -1.0 -0.3 -1.0 -0.5 -0.9 -0.6 -0.4 -0.5 -0.7 -1.1 -0.6 -0.5 -0.8 -0.2 -0.8 0.1 -0.1 -0.6 0.1 -1.1\nDiabetes diagnosed by doctor 6.7 10.9 21.2 -3.6 -3.1 -3.1 -1.7 -3.2 -3.3 -3.0 -3.0 -3.0 -3.3 -3.4 -3.4 -3.3 -3.5 -3.3 -3.6 -2.9 -3.3 -1.6 -4.0 -3.2 -3.3 -3.5 -3.9 -3.0 -3.7 -2.9 -3.3 -2.8 -3.6 -3.3 -3.5 -4.2 -4.6 -3.1 -3.6 -3.9 -3.3 -3.8 -2.7 -3.4 -3.3 -3.4 -3.2 -3.8 -3.3 -4.2 -3.0 -2.9 -2.8 -3.2 -2.0 -2.3\nEver had stillbirth, spontaneous miscarriage or termination 2.4 2.6 4.5 -1.9 -1.2 -1.4 -1.8 -1.4 -1.2 -1.4 -0.3 -0.8 -2.1 -1.7 -1.8 -1.9 -0.7 -1.3 -2.0 -1.5 -1.7 -1.2 -1.8 -2.0 -1.5 -0.6 -1.9 -1.2 -1.6 -1.8 -2.0 -1.3 -1.6 -1.9 -1.5 -2.1 -1.2 -1.7 -1.9 -1.8 -1.5 -1.4 -1.9 -2.0 -1.9 -1.7 -1.8 -2.0 -1.6 -1.8 -1.8 -1.8 0.1 -1.5 -0.9 -1.9\nFriendships satisfaction 0.4 0.5 3.2 0.7 0.7 0.7 0.9 0.5 0.6 1.2 1.0 0.7 0.8 0.3 0.5 0.7 0.8 0.6 -0.1 0.7 0.1 1.1 0.5 0.7 0.6 0.2 0.2 0.6 0.5 1.0 0.4 1.0 0.8 0.8 0.3 0.5 -0.1 0.8 0.7 -0.3 0.4 -0.3 0.8 0.5 0.6 0.7 0.7 0.6 0.3 0.2 0.6 0.9 -1.8 0.3 0.3 1.1\nQualifications: nursing, teaching 0.1 0.2 1.1 -0.2 -0.3 -0.3 -0.8 -0.3 -0.3 -0.5 -0.2 -0.1 -0.5 -0.5 -0.3 -0.4 -0.8 -0.2 -0.2 -0.2 -0.2 -0.6 -0.3 -0.4 0.0 -1.1 0.2 -0.3 -0.3 -0.4 -0.5 -0.3 -0.2 -0.3 -0.5 -0.0 0.2 -0.5 -0.6 0.4 -0.4 0.2 -0.4 -0.5 -0.1 -0.3 -0.4 0.1 -0.6 0.1 -0.4 -0.2 -0.2 -0.5 -0.4 -0.5\nCommuting to job workplace: Walk 0.3 0.3 2.4 0.4 0.3 0.3 0.4 0.3 0.7 0.7 -0.3 -0.1 0.2 -0.1 0.2 0.3 0.3 0.1 0.5 0.3 0.1 1.0 0.5 0.4 0.3 0.2 0.2 0.7 0.4 0.7 0.0 1.0 0.5 0.3 -0.2 0.6 -0.2 0.8 1.2 0.8 0.8 0.2 0.4 0.2 0.2 0.5 0.2 1.0 -0.6 0.4 0.6 1.2 -0.9 -0.1 0.1 1.6\nEye problems/disorders: Cataract 0.1 0.1 0.5 0.0 -0.2 -0.3 0.2 0.0 -0.1 0.0 0.4 -0.0 0.2 -0.4 -0.2 0.0 -0.4 -0.1 -0.2 -0.3 -0.0 0.4 0.4 0.0 -0.1 0.5 -0.6 0.6 -0.1 0.2 -0.1 0.2 0.0 -0.0 -0.3 0.0 -0.5 0.1 0.5 0.1 -0.2 -0.2 0.0 -0.2 0.1 0.0 -0.0 0.2 -0.6 -0.7 0.1 -0.0 -0.5 -0.4 -0.5 0.4\nMouth/teeth dental problems: Mouth ulcers 0.4 0.7 2.5 0.9 0.7 0.6 0.4 0.6 0.9 1.0 1.1 1.6 0.7 0.5 0.8 0.8 1.2 0.9 0.8 0.5 0.6 0.7 0.7 0.9 0.7 0.4 0.5 0.8 0.6 0.9 1.0 1.3 0.8 0.9 0.4 0.9 0.2 0.6 1.2 1.2 0.8 0.9 0.8 0.7 0.9 0.9 0.8 0.9 -0.3 0.3 0.8 1.5 0.2 1.3 0.3 1.1\nMedication for cholesterol 2.1 3.2 7.7 1.8 1.2 1.9 1.4 1.5 1.5 1.5 0.2 1.1 1.9 1.8 1.9 1.7 1.3 1.5 2.1 1.9 2.1 1.4 2.0 1.5 1.7 2.0 2.6 1.9 1.8 1.8 1.6 1.7 2.0 1.6 1.6 2.3 2.4 1.8 2.3 2.8 1.7 1.8 1.9 1.7 1.9 1.9 1.7 2.5 1.8 1.8 1.8 1.7 0.6 1.5 1.1 1.8\nMedication: Laxatives (e.g. Dulcolax, Senokot) 3.4 4.0 10.5 -2.4 -1.9 -1.6 -1.6 -1.9 -1.7 -2.0 -1.3 -1.9 -2.1 -1.8 -2.4 -2.1 -1.7 -2.0 -2.7 -1.3 -2.1 -1.5 -2.6 -2.3 -2.1 -2.2 -1.2 -1.6 -1.9 -2.2 -2.2 -1.8 -2.1 -2.3 -1.6 -2.4 -1.7 -1.9 -2.1 -3.2 -1.9 -2.1 -2.3 -1.8 -2.3 -2.2 -2.0 -2.0 -1.6 -1.6 -2.1 -2.3 -1.0 -2.6 -0.3 -1.8\nBack pain experienced in last month 1.1 1.6 4.4 -1.1 -0.8 -1.0 -1.3 -1.2 -0.8 -0.8 -1.0 -0.6 -1.0 -1.4 -1.3 -1.2 -1.6 -0.9 -1.7 -1.3 -1.6 -1.2 -0.6 -1.1 -1.6 0.1 -2.1 -1.2 -0.9 -1.1 -1.0 -1.1 -1.6 -1.1 -1.4 -1.8 -1.8 -0.6 -1.2 -1.4 -1.3 -1.9 -1.0 -1.3 -1.2 -1.3 -1.1 -1.7 -1.6 -1.7 -1.3 -0.2 -0.3 -0.7 -1.2 -1.3\nMineral and other dietary supplements 0.2 0.3 1.8 0.1 0.7 0.4 0.5 0.4 0.9 0.2 0.5 -0.2 -0.2 0.4 0.1 -0.0 0.8 0.4 0.3 0.9 0.0 0.2 0.4 -0.1 0.4 1.3 0.4 -0.7 0.7 0.1 -0.1 -0.1 0.2 -0.1 0.5 -0.0 0.5 0.7 0.1 -0.3 0.4 0.0 -0.2 0.2 -0.2 -0.1 0.1 0.6 0.4 1.3 -0.2 0.5 -0.8 -0.7 1.0 -0.1\nBreast cancer (self-reported) 1.0 1.1 3.7 0.5 0.6 1.1 1.0 1.0 1.5 0.7 0.6 0.3 0.4 1.0 0.7 0.6 1.7 0.8 1.4 1.2 1.1 1.0 1.1 0.4 1.2 0.9 1.9 1.3 1.3 1.0 0.6 0.9 1.1 0.3 1.3 1.3 1.6 0.9 1.6 1.1 1.0 1.6 0.5 1.0 0.6 0.8 0.6 1.7 0.9 1.8 0.6 0.6 0.8 0.1 1.8 0.7\nAsthma (self-reported) 1.0 2.0 11.0 -1.1 -1.2 -1.1 -1.7 -1.0 -0.7 -1.1 -0.5 -0.8 -1.2 -1.5 -1.4 -1.2 -0.9 -1.0 -1.4 -0.7 -2.1 -1.9 -1.6 -1.0 -1.1 -1.3 -1.0 -1.6 -1.1 -1.6 -1.2 -1.1 -1.7 -1.0 -0.9 -1.8 -1.0 -0.9 -1.3 -3.3 -1.5 -1.9 -2.1 -1.0 -1.7 -1.5 -1.1 -1.9 -2.0 -1.2 -1.7 -1.1 -1.1 -2.2 -0.7 -1.5\nOsteoporosis (self-reported) 5.2 6.5 13.0 2.2 2.8 3.0 2.3 2.7 2.9 2.6 3.6 2.6 2.0 2.6 2.3 2.3 3.0 2.6 2.2 3.2 2.5 2.4 2.5 2.1 2.7 2.2 2.8 2.1 2.9 2.3 2.3 2.5 2.8 2.1 3.0 2.3 2.8 2.7 2.3 1.6 2.8 2.4 2.1 2.5 2.3 2.5 2.4 2.7 3.1 2.9 2.2 2.0 1.3 2.0 3.6 2.2\nOsteoarthritis (self-reported) 0.3 0.4 2.5 -0.3 -0.8 -0.1 -0.1 -0.6 -0.5 -0.3 1.0 -0.4 -0.4 -0.8 -0.6 -0.5 -1.1 -0.7 -0.7 -0.6 -0.9 0.0 -0.2 -0.4 -0.7 -0.6 -1.0 -0.9 -0.6 -0.0 -0.4 -0.0 -0.3 -0.3 -0.9 -0.4 -0.9 0.2 -0.1 -0.9 -0.8 -1.4 -0.2 -0.8 -0.4 -0.2 -0.4 -0.5 -0.6 -0.9 -0.4 0.7 -1.6 0.4 -0.7 -0.4\nMedication: Aspirin 0.4 0.5 3.4 -0.2 -0.3 -0.3 -0.7 -0.2 -0.2 -0.5 -0.8 -0.0 -0.2 -0.1 -0.2 -0.1 -0.0 0.1 -0.4 -0.7 -0.8 -0.9 -1.0 -0.0 -0.5 -1.2 0.1 -1.9 -0.5 -0.8 0.1 -0.7 -0.9 -0.1 -0.3 -1.0 -0.9 0.1 -0.8 -1.6 -0.8 -1.4 -0.5 -0.1 -0.5 -0.5 -0.1 -0.7 -0.5 -0.1 -0.7 0.5 -1.5 -0.4 0.0 -0.9\nMedication: Gliclazide 2.4 2.7 7.0 -2.0 -1.8 -1.0 -0.2 -1.5 -1.7 -1.6 -2.2 -1.8 -1.6 -1.6 -1.6 -1.5 -1.5 -1.9 -1.7 -0.9 -1.5 -0.4 -2.4 -1.6 -1.4 -1.9 -1.9 -1.3 -1.8 -1.5 -1.4 -1.1 -1.8 -1.7 -1.6 -2.6 -2.5 -1.4 -2.0 -2.2 -1.6 -1.8 -0.9 -1.5 -1.5 -1.7 -1.4 -1.7 -1.4 -2.1 -1.3 -1.1 -1.6 -1.5 0.0 -1.0\nIllnesses of father: None of the above (group 1) 0.4 0.5 3.1 0.5 0.5 0.5 0.5 0.3 0.1 0.4 -0.0 0.3 0.9 0.7 0.7 0.6 0.1 0.5 0.8 -0.0 1.0 0.6 0.7 0.4 0.5 0.3 0.4 0.6 0.3 0.6 0.5 0.6 0.7 0.6 0.2 0.7 0.3 0.1 0.5 1.7 0.7 1.0 1.2 0.7 0.9 0.8 0.6 0.6 0.9 -0.0 0.8 0.1 1.3 1.8 -0.1 0.7\nSmoking status: Current 1.2 1.9 4.1 -1.3 -1.4 -1.6 -1.2 -1.2 -1.5 -1.6 -1.7 -1.0 -1.0 -1.2 -1.1 -1.2 -1.2 -1.4 -1.2 -1.4 -1.2 -1.3 -1.8 -1.2 -1.5 -0.8 -1.4 -1.1 -1.5 -1.6 -1.1 -1.6 -1.7 -1.1 -1.4 -1.8 -1.8 -1.8 -1.8 -1.9 -1.3 -1.3 -1.3 -1.1 -1.4 -1.6 -1.2 -2.0 -1.1 -1.4 -1.1 -1.7 0.1 -0.8 -1.4 -1.3\nForced expiratory volume in 1-second (FEV1), predicted percentage 2.2 4.7 10.0 -2.0 -1.8 -2.0 -2.4 -2.3 -2.1 -1.6 -0.3 -2.5 -1.7 -2.8 -2.4 -2.0 -2.9 -2.5 -2.3 -2.1 -2.5 -1.9 -1.8 -1.9 -2.0 -2.5 -3.2 -1.3 -2.1 -2.0 -2.3 -1.7 -2.0 -1.9 -2.2 -2.3 -2.0 -2.1 -2.5 -2.5 -2.6 -2.5 -2.0 -2.5 -1.7 -1.8 -2.0 -2.2 -2.3 -2.3 -2.1 -2.2 -2.0 -2.4 -2.3 -1.9\nWhole body water mass 0.2 1.2 8.2 -0.9 -1.4 -0.8 -1.2 -1.1 -1.0 -1.3 -2.9 -0.8 -1.0 -1.5 -1.1 -1.4 -2.0 -1.4 0.1 -0.2 -0.9 -1.4 0.2 -1.4 -1.1 -1.6 -1.2 -1.0 -0.3 -0.5 -1.7 -1.1 -0.8 -1.3 -1.4 0.1 -0.2 -0.3 -0.4 1.4 -0.4 -0.0 -0.5 -1.2 -0.5 -1.2 -1.3 0.1 -0.6 1.1 -1.2 0.2 0.2 -0.6 -1.2 -1.1\nLeg predicted mass (right) 0.2 0.9 5.6 -0.9 -1.2 -0.7 -1.0 -0.9 -0.6 -1.2 -2.4 -0.5 -1.0 -1.3 -1.1 -1.3 -1.7 -1.3 -0.0 0.1 -0.8 -1.3 0.2 -1.3 -1.0 -0.9 -1.0 -0.6 -0.1 -0.4 -1.6 -0.9 -0.6 -1.3 -1.1 0.2 0.0 -0.2 -0.2 1.2 -0.4 0.1 -0.7 -1.0 -0.5 -1.1 -1.2 0.3 -0.6 1.4 -1.1 0.2 0.1 -0.8 -0.8 -1.1\nArm fat mass (left) 2.7 11.0 19.0 -3.5 -3.4 -3.0 -3.0 -3.4 -2.8 -3.4 -2.7 -3.4 -3.7 -3.8 -3.9 -3.8 -3.2 -3.8 -3.0 -2.6 -4.0 -3.3 -2.8 -3.7 -3.6 -2.6 -3.4 -3.6 -2.8 -3.1 -3.8 -3.4 -3.3 -3.7 -3.1 -2.8 -2.3 -2.4 -2.8 -3.4 -3.6 -3.7 -3.9 -3.6 -3.5 -3.7 -3.7 -2.5 -3.6 -1.5 -3.9 -2.5 -3.4 -4.4 -2.4 -3.3\nNumber of self-reported non-cancer illnesses 0.8 1.5 7.5 -1.4 -0.4 -0.6 -0.5 -0.7 -0.6 -1.0 -0.1 -1.3 -1.2 -1.0 -1.1 -1.1 -0.4 -0.5 -1.0 -0.5 -1.3 -1.0 -1.7 -1.2 -0.7 -1.2 -1.0 -1.7 -0.9 -1.2 -1.1 -1.2 -1.5 -1.1 -0.5 -2.3 -1.2 -1.2 -2.5 -2.7 -1.1 -1.3 -0.9 -0.9 -1.2 -1.4 -0.9 -2.0 -0.5 -0.9 -1.4 -0.9 -0.8 -0.4 0.6 -1.8\nAverage weekly champagne plus white wine intake 0.1 0.2 3.0 -0.1 0.1 0.2 0.2 0.0 0.8 0.3 -1.2 -0.1 -0.3 -0.1 -0.1 -0.2 0.1 0.2 0.0 0.4 -0.1 0.6 0.5 -0.2 -0.1 0.3 -0.5 -0.1 0.2 0.4 -0.2 0.5 -0.1 -0.2 -0.4 -0.3 -0.5 0.6 0.4 0.9 0.3 0.0 0.5 -0.3 0.1 -0.1 -0.1 0.4 -0.6 0.1 -0.1 1.7 -0.7 0.2 0.4 0.3\nMiserableness 1.2 2.0 7.5 -1.5 -1.4 -1.4 -1.1 -1.6 -0.9 -0.7 -0.2 -1.0 -1.4 -2.2 -1.7 -1.6 -1.1 -1.1 -1.1 -1.6 -1.6 -0.3 -1.2 -1.6 -1.3 -1.5 -2.5 -0.9 -1.6 -0.8 -1.6 -0.5 -1.5 -1.5 -2.1 -1.9 -2.7 -0.9 -1.2 -0.8 -0.9 -1.4 -0.5 -1.9 -1.1 -1.5 -1.5 -1.8 -2.1 -2.0 -1.2 0.5 -0.3 -0.5 -1.2 -0.9\nGuilty feelings 3.1 4.6 7.0 -2.5 -2.3 -1.8 -2.0 -2.3 -1.9 -1.9 -2.2 -2.4 -2.4 -2.6 -2.4 -2.5 -2.0 -2.4 -2.0 -2.0 -2.1 -1.3 -2.3 -2.6 -1.9 -2.5 -2.1 -2.3 -2.3 -2.0 -2.6 -1.6 -2.2 -2.5 -2.6 -2.6 -2.3 -2.1 -2.2 -1.6 -1.8 -1.8 -1.7 -2.7 -1.9 -2.3 -2.4 -2.2 -2.2 -2.2 -2.1 -1.2 -1.4 -2.3 -1.1 -1.9\nWears glasses or contact lenses 4.7 5.4 10.1 2.6 2.7 2.5 2.2 2.6 3.1 2.4 0.7 2.1 2.3 2.9 2.5 2.5 3.2 2.8 2.5 2.7 2.4 1.8 2.0 2.4 2.2 2.1 2.6 1.8 2.5 2.0 2.8 2.0 1.9 2.5 2.8 1.4 1.7 2.5 2.1 1.1 2.4 2.3 1.9 2.9 2.3 2.1 2.6 2.3 2.2 2.2 2.2 2.1 2.0 1.4 3.0 2.1\nEver taken oral contraceptive pill 0.7 0.8 2.1 0.9 1.0 0.9 0.9 1.1 0.7 0.9 0.6 0.8 1.2 1.0 1.1 1.1 0.4 0.7 1.1 0.8 1.1 0.8 0.8 1.1 1.1 0.6 0.6 0.9 1.0 0.8 0.8 0.8 0.9 1.0 1.0 0.7 0.7 0.6 0.7 0.6 1.1 1.0 1.0 1.0 1.0 0.9 1.1 0.5 1.5 0.4 1.0 0.2 0.8 0.6 0.8 0.7\nHearing aid user 1.4 1.6 4.9 -1.0 -1.1 -0.9 -1.4 -1.1 -1.1 -1.2 -0.3 -0.9 -0.9 -1.2 -1.0 -1.0 -1.5 -1.0 -1.5 -0.8 -1.6 -1.6 -1.2 -0.9 -1.2 -1.0 -0.9 -1.9 -1.1 -1.4 -0.9 -1.2 -1.5 -0.9 -1.1 -1.6 -1.2 -1.0 -1.3 -1.8 -1.6 -1.9 -1.2 -1.1 -1.2 -1.2 -1.0 -1.4 -1.5 -1.4 -1.4 -0.4 -2.2 -1.2 -0.9 -1.4\nMother’s age at death 2.9 3.6 6.4 2.0 2.1 2.0 1.0 1.9 2.1 1.9 2.5 2.2 2.0 2.0 1.8 1.9 1.8 2.2 1.9 1.7 1.9 1.0 2.2 1.9 2.0 1.4 2.1 1.8 2.1 1.8 2.0 1.7 2.0 1.9 2.1 2.0 2.5 1.8 1.7 2.1 1.8 2.2 1.7 2.1 2.0 2.0 1.9 1.9 1.8 1.7 1.6 1.2 2.3 2.2 1.3 1.4\nFinancial situation satisfaction 0.7 0.8 2.7 -0.7 -1.0 -0.9 -0.8 -0.8 -1.0 -0.9 -0.3 -0.6 -0.3 -0.7 -0.6 -0.6 -0.9 -0.5 -1.7 -0.8 -1.0 -0.8 -1.2 -0.6 -0.8 -0.6 -0.7 -1.1 -1.3 -0.7 -0.6 -0.7 -1.1 -0.5 -0.9 -1.1 -0.9 -0.8 -0.9 -1.2 -1.4 -1.6 -0.7 -0.5 -0.9 -0.8 -0.5 -1.0 -1.4 -1.5 -0.7 -0.5 -1.1 -0.3 -1.2 -0.7\nTinnitus: Yes, now most or all of the time 2.3 2.7 5.6 -1.4 -1.1 -1.6 -1.9 -1.7 -1.1 -0.8 -0.7 -1.5 -1.5 -2.1 -1.7 -1.5 -1.7 -1.3 -1.6 -1.5 -2.1 -1.4 -1.4 -1.3 -1.6 -1.7 -2.2 -1.9 -1.5 -1.5 -1.6 -1.1 -1.7 -1.4 -1.8 -2.0 -2.4 -1.2 -1.8 -1.8 -1.5 -2.0 -1.4 -1.9 -1.5 -1.6 -1.5 -2.1 -2.4 -1.9 -1.6 -0.4 -1.8 -1.5 -1.6 -1.5\nCommuting to job workplace: Public transport 2.2 2.6 5.8 -1.6 -1.2 -1.5 -1.5 -1.5 -1.2 -1.6 -2.1 -1.6 -1.6 -1.5 -1.6 -1.6 -1.2 -1.5 -1.4 -1.1 -1.9 -1.5 -1.6 -1.5 -1.5 -0.6 -1.1 -1.4 -1.3 -1.7 -1.6 -1.6 -1.8 -1.5 -1.4 -2.0 -1.2 -1.2 -1.7 -2.3 -2.1 -2.2 -1.9 -1.5 -1.8 -1.8 -1.5 -1.4 -2.2 -1.0 -1.9 -1.3 -2.1 -2.4 -1.2 -1.4\nEye problems/disorders: Glaucoma 0.2 0.2 1.6 0.3 0.4 0.1 0.2 0.1 0.3 0.4 1.3 0.7 0.6 -0.1 0.2 0.4 0.4 0.4 0.5 0.0 0.3 0.2 0.2 0.5 0.5 -1.0 0.1 0.5 0.1 0.4 0.0 0.2 0.2 0.3 0.4 0.2 0.0 0.0 0.0 0.5 0.4 0.6 0.5 0.4 0.5 0.3 0.3 0.1 0.4 0.1 0.3 0.1 0.9 1.1 -0.3 0.1\nMedication: Blood pressure 2.4 4.5 11.5 -2.3 -1.4 -1.9 -1.7 -1.8 -1.6 -2.1 -0.9 -1.7 -2.8 -1.8 -2.2 -2.2 -0.8 -1.6 -2.2 -1.5 -2.5 -2.2 -2.5 -2.1 -2.1 -1.7 -2.0 -2.8 -1.9 -2.5 -1.8 -2.7 -2.5 -2.2 -1.3 -2.8 -1.7 -2.1 -3.0 -3.4 -1.9 -2.1 -2.5 -2.0 -2.8 -2.4 -2.2 -2.8 -1.5 -1.2 -2.6 -2.3 -1.2 -2.1 -0.6 -2.6\nPain type(s) experienced in last month: Hip pain 0.9 1.1 5.4 -0.8 -0.6 -0.8 -0.6 -0.8 -0.8 -0.9 0.2 -0.4 -0.5 -0.7 -1.0 -0.7 -0.5 -0.6 -1.1 -1.0 -1.4 -1.0 -0.9 -0.7 -1.2 -0.8 -1.1 -1.9 -1.0 -0.9 -0.7 -1.1 -1.2 -0.7 -0.7 -1.4 -1.1 -0.7 -1.0 -2.3 -1.7 -1.9 -1.1 -0.6 -1.1 -1.0 -0.7 -1.2 -1.2 -1.4 -1.1 -0.6 -1.0 -0.6 -0.8 -1.3\nSupplements: Fish oil (including cod liver oil) 0.2 0.3 1.9 0.3 -0.6 -0.3 -0.1 -0.2 -0.8 0.1 0.3 0.2 0.4 -0.1 0.2 0.3 -0.9 -0.3 0.2 -0.9 0.3 0.1 0.2 0.5 -0.2 -0.5 -0.0 1.0 -0.6 0.2 0.4 0.2 0.3 0.5 -0.4 0.7 -0.2 -0.4 0.5 0.6 -0.2 0.2 0.3 -0.0 0.3 0.5 0.1 -0.2 -0.1 -1.1 0.4 -0.6 0.8 1.1 -1.4 0.5\nHigh cholesterol (Self-reported) 0.8 1.5 8.0 -1.0 -0.8 -1.0 -0.5 -0.7 -1.0 -1.1 -0.6 -0.7 -0.7 -0.8 -0.9 -0.7 -1.2 -0.8 -1.6 -0.9 -1.2 -1.0 -1.9 -0.6 -0.9 -1.4 -1.0 -1.3 -1.2 -1.3 -0.6 -1.3 -1.7 -0.8 -0.7 -2.1 -2.0 -1.1 -1.8 -2.8 -1.5 -1.6 -1.1 -0.7 -1.1 -1.2 -0.7 -1.7 -0.9 -1.4 -1.0 -0.9 -1.2 -1.2 -0.0 -1.4\nMedication: Bendroflumethiazide 0.7 1.1 4.3 -1.5 -0.4 -0.6 -0.3 -0.8 -0.9 -1.0 -1.1 -1.2 -1.3 -0.8 -1.2 -1.2 -0.0 -0.9 -0.8 -0.3 -1.0 -0.2 -1.3 -1.3 -1.0 -0.5 -1.8 -0.7 -0.5 -0.9 -1.0 -0.8 -1.2 -1.3 -0.7 -2.1 -1.5 -0.6 -1.8 -1.9 -0.5 -1.1 -0.8 -1.1 -1.2 -1.3 -1.0 -1.3 -0.4 -0.4 -1.1 -1.1 -0.3 -1.3 0.7 -0.7\nMedication: Paracetamol 2.8 4.4 8.2 -2.1 -2.1 -2.1 -1.7 -1.9 -2.4 -2.3 -2.5 -2.1 -1.9 -1.6 -1.9 -1.9 -2.0 -1.9 -2.1 -1.9 -1.9 -1.9 -2.5 -1.9 -2.5 -1.8 -1.9 -2.4 -2.2 -2.2 -1.9 -2.1 -2.5 -1.9 -2.2 -2.7 -2.8 -2.1 -2.6 -2.4 -2.1 -2.3 -1.7 -1.9 -2.2 -2.2 -1.9 -2.9 -1.8 -2.4 -1.8 -1.9 0.1 -1.3 -1.4 -2.1\nMedication: Lisinopril 0.3 0.4 2.7 0.5 0.9 0.9 0.4 0.8 0.7 0.5 -0.1 0.4 0.4 0.6 0.6 0.5 0.0 0.6 0.8 1.3 0.4 -0.0 -0.0 0.5 0.9 -0.0 0.2 0.5 0.9 -0.0 0.9 0.2 0.4 0.5 1.1 -0.1 0.3 0.5 -0.3 -0.8 0.6 0.4 0.2 0.8 0.6 0.4 0.7 0.2 1.1 1.1 0.2 -0.2 -0.2 -0.4 1.6 0.2\nMedication: Atorvastatin 3.1 3.9 7.3 -1.8 -2.3 -1.9 -1.8 -1.9 -1.9 -2.0 -0.6 -2.0 -2.0 -2.0 -2.0 -1.9 -2.4 -2.2 -2.3 -2.0 -2.3 -2.0 -1.9 -1.7 -2.0 -1.9 -0.9 -2.1 -2.0 -2.0 -1.8 -2.0 -2.0 -1.8 -1.8 -1.7 -1.7 -1.8 -1.6 -2.6 -2.2 -2.3 -2.4 -1.9 -2.1 -1.8 -1.9 -1.7 -2.1 -1.7 -2.1 -1.9 -2.7 -2.5 -1.5 -1.6\nIllnesses of father: High blood pressure 1.5 1.9 3.8 -1.2 -1.5 -1.4 -1.7 -1.3 -1.3 -1.3 -0.0 -1.0 -1.3 -1.4 -1.4 -1.3 -1.0 -1.4 -1.5 -1.5 -1.7 -1.8 -1.5 -1.2 -1.4 -1.4 -1.3 -1.3 -1.2 -1.5 -1.3 -1.5 -1.3 -1.3 -1.0 -0.9 -0.6 -1.2 -1.0 -1.6 -1.4 -1.3 -1.9 -1.4 -1.6 -1.4 -1.3 -1.3 -1.4 -0.7 -1.5 -1.3 -1.2 -1.9 -1.4 -1.7\nAlcohol drinker status: Never 6.6 7.9 10.4 -3.1 -3.2 -2.5 -2.6 -2.8 -3.0 -3.2 -2.0 -2.7 -2.9 -2.2 -2.9 -2.9 -2.7 -2.9 -3.1 -2.5 -2.8 -2.8 -3.2 -3.0 -3.0 -2.1 -1.9 -3.0 -3.0 -3.2 -3.2 -2.9 -3.0 -3.0 -2.5 -3.1 -2.4 -3.0 -2.7 -3.1 -2.8 -2.8 -2.8 -2.7 -3.1 -2.9 -2.8 -2.6 -2.2 -3.0 -2.9 -2.9 -2.9 -3.0 -1.4 -2.6\nEver smoked 0.2 0.4 7.3 -0.4 0.3 -0.0 0.0 0.1 0.6 0.2 -2.7 -0.2 -0.1 -0.1 -0.1 -0.3 1.0 0.3 0.9 0.2 0.2 0.1 -0.0 -0.5 -0.1 0.4 -0.6 -0.4 0.3 0.0 -0.6 -0.1 -0.5 -0.4 -0.1 -0.8 -0.5 -0.0 -0.4 0.6 0.4 0.5 0.4 -0.0 0.0 -0.5 -0.2 -0.5 -0.0 0.6 -0.1 0.8 1.8 0.2 0.7 -0.5\nBasal metabolic rate 0.4 2.0 9.1 -1.4 -1.9 -1.2 -1.5 -1.5 -1.4 -1.7 -3.0 -1.3 -1.5 -1.9 -1.6 -1.8 -2.3 -2.0 -0.4 -0.7 -1.5 -1.8 -0.3 -1.8 -1.6 -1.8 -1.6 -1.5 -0.7 -1.0 -2.1 -1.5 -1.2 -1.7 -1.8 -0.3 -0.6 -0.6 -0.7 0.6 -1.0 -0.6 -1.1 -1.6 -1.0 -1.6 -1.7 -0.3 -1.1 0.8 -1.7 -0.2 -0.4 -1.3 -1.5 -1.5\nLeg fat percentage (left) 3.4 12.4 21.1 -3.7 -3.5 -3.3 -3.2 -3.7 -3.0 -3.4 -1.9 -3.7 -3.9 -4.0 -4.1 -3.9 -2.5 -3.8 -3.4 -3.2 -4.3 -3.3 -3.2 -3.7 -3.8 -2.9 -3.4 -4.0 -3.2 -3.4 -3.6 -3.6 -3.4 -3.8 -3.2 -3.0 -2.5 -2.7 -2.9 -4.3 -4.0 -4.3 -4.3 -3.8 -3.9 -3.7 -3.8 -2.8 -3.9 -2.1 -4.0 -3.0 -4.0 -4.6 -2.6 -3.3\nArm fat-free mass (left) 0.4 2.1 8.8 -1.3 -1.9 -1.3 -1.5 -1.6 -1.5 -1.6 -3.0 -1.4 -1.4 -2.0 -1.6 -1.7 -2.4 -1.9 -0.4 -0.9 -1.6 -1.8 -0.3 -1.7 -1.7 -2.0 -1.6 -1.7 -0.9 -0.9 -2.0 -1.5 -1.2 -1.6 -1.9 -0.3 -0.7 -0.7 -0.7 0.7 -1.0 -0.8 -1.0 -1.7 -0.9 -1.5 -1.7 -0.4 -1.3 0.3 -1.6 -0.1 -0.5 -1.2 -1.8 -1.3\nNumber of operations (self-reported) 0.7 1.0 3.8 -0.6 -0.8 -0.6 -0.8 -1.0 -0.6 -0.4 -0.3 -1.2 -0.7 -1.3 -0.9 -0.7 -0.9 -0.8 -1.2 -1.3 -1.3 -0.4 -0.7 -0.5 -1.1 -1.0 -1.0 -1.6 -0.9 -0.6 -0.9 -0.2 -0.9 -0.6 -1.1 -1.1 -1.6 -0.3 -0.2 -1.7 -1.2 -1.5 -0.9 -0.9 -0.7 -0.6 -0.7 -0.6 -1.9 -1.1 -0.8 -0.1 -2.0 -1.6 -1.0 0.0\nAverage weekly beer plus cider intake 1.4 2.0 9.7 -1.5 -1.4 -1.6 -1.6 -1.3 -1.1 -1.7 -3.1 -1.6 -1.3 -1.1 -1.2 -1.5 -0.3 -1.2 -1.0 -0.8 -1.1 -1.9 -1.8 -1.6 -1.3 -0.7 -0.6 -1.7 -1.2 -1.8 -1.2 -2.0 -1.5 -1.6 -0.8 -1.0 -0.0 -1.5 -1.2 -0.9 -1.2 -1.0 -1.6 -1.0 -1.6 -1.7 -1.4 -1.3 -0.9 0.0 -1.7 -1.7 -1.1 -2.0 -1.0 -1.8\nIrritability 0.1 0.1 1.0 -0.1 -0.5 0.1 -0.5 -0.2 0.1 0.2 1.0 -0.2 -0.4 -0.5 -0.2 -0.3 0.0 -0.2 0.2 -0.3 -0.3 -0.3 0.2 -0.2 0.2 -0.7 0.0 0.0 -0.2 0.1 -0.6 0.3 0.3 -0.3 -0.4 0.5 0.7 -0.1 0.4 0.8 0.0 0.3 -0.1 -0.5 -0.0 0.1 -0.3 0.1 -0.4 -0.2 -0.4 0.3 -0.5 -0.3 -0.2 -0.3\nRisk taking 0.1 0.2 0.9 -0.2 -0.6 -0.4 -0.3 -0.3 -0.6 -0.5 -0.6 0.0 -0.2 -0.4 -0.1 -0.2 -0.8 -0.2 -0.0 -0.4 -0.2 -0.5 -0.5 -0.2 -0.2 0.1 -0.3 -0.8 -0.5 -0.3 -0.3 -0.3 -0.7 -0.2 -0.6 -0.6 -0.8 -0.6 -0.8 0.2 -0.3 -0.2 0.2 -0.5 -0.1 -0.4 -0.2 -0.9 -0.7 -0.8 -0.2 0.2 0.2 0.1 -0.6 -0.5\nEver had prostate specific antigen (PSA) test 0.1 0.1 1.3 0.3 -0.7 0.0 0.1 -0.0 -0.2 -0.1 -1.1 -0.2 -0.0 0.0 0.4 0.1 -0.6 -0.2 0.4 -0.1 0.4 -0.2 -0.5 0.2 0.2 -1.1 0.4 0.4 -0.4 -0.1 0.2 0.3 0.1 0.2 -0.2 0.3 -0.0 -0.2 0.3 1.2 -0.0 0.9 0.3 0.0 0.5 0.2 0.1 0.3 -0.2 0.0 0.1 0.4 0.1 0.1 0.3 -0.1\nFractured/broken bones in last 5 years 0.8 1.0 2.2 -1.3 -1.5 -0.9 -0.6 -1.3 -1.3 -1.3 0.2 -1.1 -1.4 -0.8 -1.1 -1.2 -0.9 -1.1 -1.1 -1.0 -0.9 -0.8 -1.4 -1.2 -1.0 -0.6 -0.2 -0.6 -1.3 -0.9 -1.2 -1.1 -0.8 -1.3 -1.2 -0.6 -0.6 -1.1 -1.2 -0.6 -0.6 -0.7 -1.0 -1.3 -1.3 -1.1 -1.2 -0.8 -0.3 -0.6 -1.0 -1.0 -0.9 -0.4 -0.7 -1.0\nAge started oral contraceptive pill 0.5 0.6 2.2 -1.0 -0.9 -0.5 -1.0 -0.7 -0.5 -0.9 -0.5 -0.4 -1.1 -0.5 -1.0 -1.0 -0.4 -0.8 -0.3 -0.6 -0.7 -1.0 -0.3 -1.2 -0.7 -0.9 0.1 -0.3 -0.6 -0.7 -1.1 -0.9 -0.3 -1.2 -0.6 0.1 0.3 -0.6 -0.3 -0.2 -0.4 -0.3 -1.0 -0.6 -1.0 -0.8 -1.0 -0.0 -0.3 -0.0 -1.1 -1.5 -0.9 -1.4 -0.1 -0.4\nDiastolic blood pressure, automated reading 6.0 18.6 34.2 -4.4 -4.2 -4.2 -3.9 -4.2 -5.3 -4.8 -1.6 -4.2 -4.4 -4.1 -4.5 -4.2 -4.0 -4.3 -4.5 -3.9 -4.4 -4.3 -5.0 -4.1 -4.4 -4.1 -3.7 -3.8 -4.5 -4.8 -4.0 -4.8 -4.4 -4.2 -3.5 -4.4 -3.5 -4.7 -5.3 -5.8 -4.5 -4.4 -4.8 -4.2 -4.6 -4.5 -4.2 -4.8 -3.0 -3.9 -4.4 -5.8 -2.6 -4.2 -3.0 -4.5\nEver depressed for a whole week 0.4 0.5 2.9 -0.5 -0.5 -0.7 -0.7 -0.6 -0.5 -0.4 -0.0 -0.3 -0.2 -0.5 -0.5 -0.5 -0.8 -0.2 -0.9 -0.9 -0.7 -0.5 -0.8 -0.4 -0.8 -0.2 -1.1 -0.6 -0.6 -0.6 -0.5 -0.2 -0.9 -0.4 -0.9 -1.2 -1.7 -0.4 -1.0 -0.7 -1.0 -1.1 -0.1 -0.6 -0.4 -0.8 -0.5 -0.9 -1.4 -1.1 -0.6 0.5 -0.6 0.3 -0.6 -0.6\nUnable to work because of sickness or disability 0.6 0.8 2.8 -0.7 -1.0 -1.2 -0.2 -1.1 -1.0 -0.7 -0.2 -0.5 -0.6 -1.0 -0.7 -0.7 -0.6 -0.8 -0.9 -1.3 -0.7 -0.1 -1.2 -0.7 -1.0 -0.3 -1.3 -0.9 -1.4 -0.4 -0.9 -0.8 -0.9 -0.6 -1.1 -0.9 -1.6 -0.9 -0.8 -0.8 -1.1 -1.2 -0.5 -0.8 -0.8 -0.8 -0.7 -1.2 -1.1 -1.7 -0.5 -1.1 -0.7 -0.4 -1.2 -0.4\nCommuting to job workplace: Cycle 3.6 4.3 6.4 1.8 2.2 2.3 2.0 2.3 2.4 2.1 0.4 1.7 1.8 2.1 2.1 1.9 2.4 2.2 2.3 2.2 2.4 2.2 2.0 1.8 2.1 1.8 2.3 2.4 2.2 2.0 1.9 2.4 1.9 1.8 1.7 1.4 1.5 1.9 1.8 2.4 2.5 2.4 2.4 2.1 2.1 2.0 2.0 2.0 2.0 1.7 2.1 2.5 1.9 2.3 2.5 2.1\nMyopia 0.6 0.8 2.9 0.6 1.2 0.9 1.0 1.1 1.1 0.3 -0.8 1.4 0.5 1.7 1.0 0.7 1.6 1.3 0.6 1.3 1.0 0.3 0.4 0.6 0.7 1.3 1.5 0.6 0.9 0.5 0.8 0.1 0.1 0.6 1.2 -0.3 0.7 0.5 0.1 -0.1 0.6 1.1 0.7 1.1 0.5 0.3 0.8 0.1 1.4 0.8 0.4 0.6 1.7 0.9 1.7 -0.4\nVascular/heart problems diagnosed by doctor 3.9 10.5 24.7 3.5 2.4 3.1 2.6 2.8 2.7 3.2 1.4 3.2 3.6 3.2 3.4 3.3 2.0 2.8 3.5 3.0 3.3 2.8 4.0 3.2 3.2 3.1 3.1 3.6 3.2 3.5 2.9 3.5 3.8 3.3 2.4 4.4 3.3 3.3 4.2 5.0 3.1 3.1 3.6 3.1 3.5 3.6 3.1 4.1 2.4 2.7 3.5 3.5 1.5 3.4 1.1 3.9\nCholesterol lowering medication 1.5 2.2 6.4 -1.2 -0.7 -1.4 -1.3 -1.0 -0.9 -1.1 -0.4 -0.2 -1.4 -1.2 -1.3 -1.2 -0.8 -0.9 -2.0 -1.6 -1.8 -1.3 -1.6 -1.0 -1.5 -1.6 -1.9 -2.2 -1.5 -1.6 -0.9 -1.5 -2.0 -1.1 -1.4 -2.5 -2.5 -1.2 -1.9 -2.5 -1.5 -2.0 -1.4 -1.2 -1.6 -1.6 -1.2 -2.1 -1.9 -1.9 -1.4 -0.4 -0.9 -0.9 -0.9 -1.4\nMedication: Omeprazole (e.g. Zanprol) 1.0 1.2 2.4 -1.3 -1.1 -0.7 -1.3 -1.0 -0.9 -0.8 -0.4 -1.2 -1.2 -1.0 -1.4 -1.1 -0.9 -0.8 -1.4 -0.9 -1.3 -1.0 -1.1 -1.1 -1.1 -1.5 -1.4 -1.5 -1.1 -1.1 -1.2 -0.8 -1.1 -1.2 -1.1 -1.4 -1.5 -0.8 -1.2 -1.6 -1.2 -1.0 -1.0 -1.2 -1.0 -1.3 -1.1 -1.3 -1.2 -0.8 -1.3 -0.5 0.2 -0.9 0.1 -1.3\nPain experienced in last month 2.6 4.3 10.2 1.7 1.8 2.1 1.9 2.3 2.2 1.7 -0.3 1.8 1.7 2.5 2.0 1.8 1.9 2.0 2.4 2.6 2.6 1.8 1.8 1.6 2.3 1.7 2.5 2.0 2.2 1.8 1.8 1.9 1.9 1.6 2.1 1.8 2.1 1.7 1.8 2.4 2.7 3.1 2.0 2.1 2.1 1.8 1.9 2.0 2.5 2.5 2.0 1.6 3.2 1.5 2.6 1.8\nSupplements: Calcium 0.1 0.1 0.7 0.1 0.3 0.4 0.1 0.4 0.4 0.2 -0.1 0.4 0.4 0.4 0.4 0.3 0.4 0.3 -0.0 -0.2 0.4 0.2 -0.1 0.3 0.4 -0.5 0.1 0.1 0.1 -0.2 0.4 0.4 -0.1 0.2 0.1 -0.7 -0.4 0.1 -0.2 0.3 0.3 0.2 0.7 0.4 0.5 0.1 0.4 -0.1 0.2 -0.4 0.2 0.8 -0.0 0.8 0.8 0.2\nBasal cell carcinoma (self-reported) 0.9 1.1 4.2 -0.6 -0.7 -0.9 -0.8 -1.1 -0.9 -0.5 -1.9 -1.8 -0.4 -1.6 -1.0 -0.7 -1.7 -1.3 -0.3 -1.2 -1.3 -0.6 -0.7 -0.5 -1.2 -1.9 -1.6 -2.0 -0.8 -0.6 -0.8 -0.7 -0.8 -0.6 -1.2 -0.8 -1.2 -0.1 -0.8 -0.5 -0.8 -1.6 -0.5 -1.1 -0.6 -0.8 -0.8 -0.9 -1.0 -0.5 -0.8 -0.0 -1.7 -1.3 -1.5 -0.5\nHeart attack/myocardial infarction (self-reported) 0.1 0.1 1.1 0.0 -0.1 -0.1 -0.3 -0.1 -0.1 0.0 0.5 -1.1 -0.0 -0.1 -0.1 0.1 -0.2 -0.1 -0.4 -0.8 -0.2 -0.1 0.0 0.2 -0.2 -0.3 -0.1 -0.6 -0.3 -0.2 0.0 0.0 -0.2 0.1 -0.3 -0.3 -0.6 -0.0 -0.1 -0.3 -0.2 -0.4 -0.0 -0.1 -0.1 0.1 0.0 -0.4 -0.3 -0.7 -0.0 0.2 -0.0 0.5 -0.4 -0.1\nDeep venous thrombosis (DVT) (self-reported) 1.4 1.9 5.6 -1.6 -1.0 -0.9 -1.3 -1.0 -0.8 -1.4 -1.4 -1.6 -1.7 -0.8 -1.2 -1.5 -0.8 -0.9 -1.4 -0.4 -1.5 -1.7 -1.8 -1.5 -1.0 -0.6 -0.8 -2.4 -0.9 -1.8 -1.3 -1.9 -1.8 -1.5 -0.7 -2.2 -0.8 -1.1 -2.1 -1.9 -0.8 -1.5 -1.3 -1.0 -1.5 -1.8 -1.3 -1.6 -0.8 -0.3 -1.8 -0.7 -1.4 -1.5 0.2 -1.5\nHeart disease (siblings) 1.5 1.9 6.9 -1.4 -1.1 -1.4 -1.7 -1.1 -0.7 -1.3 -0.5 -1.5 -1.4 -1.3 -1.5 -1.4 0.1 -1.1 -1.7 -1.2 -1.5 -1.5 -1.1 -1.4 -1.2 -0.1 -0.8 -1.5 -0.9 -1.5 -1.1 -1.4 -1.4 -1.4 -0.7 -1.2 -0.8 -1.3 -0.8 -2.4 -1.9 -1.4 -2.1 -1.2 -1.7 -1.5 -1.3 -1.3 -1.7 -0.6 -1.7 -1.6 -1.1 -2.6 -0.5 -1.7\nAlcohol drinker status: Previous 0.4 0.4 1.3 0.6 0.5 0.6 0.5 0.6 0.8 0.8 -0.1 -0.3 0.8 0.5 0.7 0.8 0.3 0.6 0.9 0.6 0.6 0.8 0.3 0.8 0.8 -0.2 -0.0 0.8 0.8 0.8 0.6 1.1 0.6 0.7 0.6 0.7 -0.2 0.8 0.7 0.5 0.6 0.6 0.8 0.7 0.8 0.6 0.7 0.7 -0.1 0.9 0.7 0.9 0.5 0.4 0.7 1.0\nPack years of smoking 4.6 6.8 11.4 -2.8 -2.9 -2.6 -2.5 -2.7 -2.7 -3.2 -1.9 -2.3 -2.8 -2.3 -2.9 -2.9 -1.6 -2.6 -2.4 -2.4 -3.0 -3.0 -2.6 -2.9 -2.9 -1.5 -1.7 -3.2 -2.5 -2.8 -2.6 -3.4 -2.8 -2.9 -2.1 -2.2 -1.2 -2.3 -2.6 -2.8 -2.9 -2.8 -3.1 -2.5 -3.1 -2.9 -2.8 -2.1 -2.2 -1.3 -3.1 -2.8 -1.9 -2.3 -2.1 -3.1\nImpedance of whole body 0.1 0.6 5.2 0.3 -0.6 -0.8 -0.3 -0.4 -1.0 -0.0 1.0 -0.8 0.3 -0.0 0.2 0.5 -0.3 -0.4 -1.0 -1.7 -0.0 -0.0 -1.1 0.7 -0.4 -0.3 -0.1 0.4 -1.0 -0.6 0.8 0.0 -0.2 0.6 -0.1 -0.2 -1.2 -1.3 -0.3 -1.6 -1.1 -0.7 -0.6 0.1 -0.3 0.3 0.2 -1.1 -0.8 -2.3 0.3 -1.9 -0.7 -0.2 -1.3 0.3\nLeg fat mass (left) 3.0 11.6 18.2 -3.6 -3.6 -3.2 -3.2 -3.6 -3.0 -3.5 -2.5 -3.5 -3.8 -4.0 -4.0 -3.9 -3.0 -3.9 -3.1 -2.9 -4.1 -3.3 -2.8 -3.8 -3.7 -3.0 -3.3 -3.7 -3.0 -3.2 -3.7 -3.5 -3.3 -3.8 -3.3 -2.7 -2.3 -2.5 -2.8 -3.4 -3.8 -3.9 -4.0 -3.7 -3.6 -3.6 -3.8 -2.5 -3.5 -1.6 -4.0 -2.7 -3.6 -4.3 -2.7 -3.4\nArm predicted mass (left) 0.5 2.6 9.8 -1.5 -2.1 -1.4 -1.7 -1.8 -1.7 -1.9 -3.1 -1.6 -1.5 -2.1 -1.8 -1.9 -2.7 -2.1 -0.6 -1.1 -1.8 -2.0 -0.5 -1.9 -1.9 -2.2 -1.8 -2.0 -1.1 -1.1 -2.2 -1.7 -1.4 -1.8 -2.1 -0.5 -0.9 -0.8 -1.0 0.4 -1.2 -1.1 -1.2 -1.9 -1.1 -1.7 -1.9 -0.7 -1.4 0.2 -1.8 -0.3 -0.7 -1.3 -2.0 -1.6