Lukasz Seweryn Player Profile, Energa Czarni Slupsk, International Stats, Game Logs, Awards - RealGM\nLukasz Seweryn SG #9\nJun 24, 2004 - Lukasz Seweryn went undrafted in the 2004 NBA Draft making him an Unrestricted FA.\n2009-10 Asseco Prokom Gdynia Euroleague 7 0 4.3 0.71 1.00 .714 0.57 0.86 .667 0.00 0.00 .000 0.00 0.43 0.43 0.14 0.00 0.00 0.86 0.00 2.00\n2011-12 * All Teams All Leagues 45 24 15.7 1.89 4.31 .438 1.47 3.47 .423 0.18 0.24 .727 0.18 0.67 0.84 0.51 0.42 0.02 1.40 0.42 5.42\n2011-12 * Asseco Prokom Gdynia P-TBL 21 12 15.6 1.71 4.10 .419 1.43 3.33 .429 0.38 0.52 .727 0.19 0.90 1.10 0.62 0.43 0.05 1.38 0.43 5.24\n2011-12 * Asseco Prokom Gdynia VTB United 14 6 16.6 2.14 4.50 .476 1.57 3.43 .458 0.00 0.00 .000 0.00 0.57 0.57 0.57 0.43 0.00 1.57 0.57 5.86\n2011-12 * Asseco Prokom Gdynia Euroleague 10 6 14.7 1.90 4.50 .422 1.40 3.80 .368 0.00 0.00 .000 0.40 0.30 0.70 0.20 0.40 0.00 1.20 0.20 5.20\n2012-13 * All Teams All Leagues 44 9 13.2 1.25 2.64 .474 0.89 2.09 .424 0.18 0.27 .667 0.09 0.57 0.66 0.45 0.30 0.05 1.70 0.48 3.57\n2012-13 * Stelmet Zielona Gora P-TBL 26 3 12.8 1.15 2.35 .492 0.77 1.85 .417 0.23 0.31 .750 0.08 0.35 0.42 0.42 0.31 0.00 1.65 0.54 3.31\n2012-13 * BC Anwil P-TBL 12 4 12.9 1.58 2.75 .576 1.17 2.25 .519 0.08 0.17 .500 0.08 0.92 1.00 0.33 0.25 0.17 2.17 0.33 4.42\n2012-13 * Stelmet Zielona Gora Eurocup 6 2 15.9 1.00 3.67 .273 0.83 2.83 .294 0.17 0.33 .500 0.17 0.83 1.00 0.83 0.33 0.00 1.00 0.50 3.00\n2013-14 Asseco Prokom Gdynia P-TBL 36 35 27.0 2.94 7.14 .412 2.11 5.47 .386 0.36 0.61 .591 0.47 1.42 1.89 0.64 0.64 0.08 2.19 0.94 8.36\n2014-15 Energa Czarni Slupsk P-TBL 28 1 10.0 0.75 2.18 .344 0.61 1.75 .347 0.29 0.36 .800 0.18 0.46 0.64 0.14 0.18 0.00 1.39 0.21 2.39\n2015-16 Energa Czarni Slupsk P-TBL 41 33 22.6 2.44 5.61 .435 1.95 4.68 .417 0.41 0.51 .810 0.39 1.20 1.59 0.44 0.63 0.07 2.41 0.63 7.24\n2016-17 Energa Czarni Slupsk P-TBL 38 27 18.3 1.42 3.39 .419 1.13 2.84 .398 0.18 0.29 .636 0.21 0.63 0.84 0.45 0.63 0.08 1.87 0.55 4.16\n2017-18 Energa Czarni Slupsk P-TBL 19 18 22.6 2.26 6.00 .377 1.84 4.89 .376 0.26 0.42 .625 0.21 0.79 1.00 0.68 0.37 0.05 1.37 0.42 6.63\n2009-10 Asseco Prokom Gdynia Euroleague 7 0 29.9 5 7 .714 4 6 .667 0 0 .000 0 3 3 1 0 0 6 0 14\n2011-12 * All Teams All Leagues 45 24 705.7 85 194 .438 66 156 .423 8 11 .727 8 30 38 23 19 1 63 19 244\n2011-12 * Asseco Prokom Gdynia P-TBL 21 12 326.7 36 86 .419 30 70 .429 8 11 .727 4 19 23 13 9 1 29 9 110\n2011-12 * Asseco Prokom Gdynia VTB United 14 6 231.9 30 63 .476 22 48 .458 0 0 .000 0 8 8 8 6 0 22 8 82\n2011-12 * Asseco Prokom Gdynia Euroleague 10 6 147.1 19 45 .422 14 38 .368 0 0 .000 4 3 7 2 4 0 12 2 52\n2012-13 * All Teams All Leagues 44 9 583 55 116 .474 39 92 .424 8 12 .667 4 25 29 20 13 2 75 21 157\n2012-13 * Stelmet Zielona Gora P-TBL 26 3 332.9 30 61 .492 20 48 .417 6 8 .750 2 9 11 11 8 0 43 14 86\n2012-13 * BC Anwil P-TBL 12 4 154.6 19 33 .576 14 27 .519 1 2 .500 1 11 12 4 3 2 26 4 53\n2012-13 * Stelmet Zielona Gora Eurocup 6 2 95.5 6 22 .273 5 17 .294 1 2 .500 1 5 6 5 2 0 6 3 18\n2013-14 Asseco Prokom Gdynia P-TBL 36 35 970.7 106 257 .412 76 197 .386 13 22 .591 17 51 68 23 23 3 79 34 301\n2014-15 Energa Czarni Slupsk P-TBL 28 1 279.3 21 61 .344 17 49 .347 8 10 .800 5 13 18 4 5 0 39 6 67\n2015-16 Energa Czarni Slupsk P-TBL 41 33 925.8 100 230 .435 80 192 .417 17 21 .810 16 49 65 18 26 3 99 26 297\n2016-17 Energa Czarni Slupsk P-TBL 38 27 694.1 54 129 .419 43 108 .398 7 11 .636 8 24 32 17 24 3 71 21 158\n2017-18 Energa Czarni Slupsk P-TBL 19 18 429.4 43 114 .377 35 93 .376 5 8 .625 4 15 19 13 7 1 26 8 126\n2009-10 Asseco Prokom Gdynia Euroleague 7 0 0 0 0 0 0 0 .030 0.00 0.00 0.00 3 4 .429 0.20 -0.01 0.19\n2011-12 * All Teams All Leagues 45 24 0 0 0 0 0 0 .091 1.21 1.00 0.06 24 21 .533 1.33 0.88 2.22\n2011-12 * Asseco Prokom Gdynia P-TBL 21 12 0 0 0 0 0 0 .082 1.44 1.00 0.13 16 5 .762 0.60 0.51 1.11\n2011-12 * Asseco Prokom Gdynia VTB United 14 6 0 0 0 0 0 0 .105 1.00 0.75 0.00 7 7 .500 0.50 0.31 0.80\n2011-12 * Asseco Prokom Gdynia Euroleague 10 6 0 0 0 0 0 0 .094 1.00 2.00 0.00 1 9 .100 0.25 0.08 0.33\n2012-13 * All Teams All Leagues 44 9 0 0 0 0 0 0 .060 0.95 0.62 0.10 28 16 .636 0.74 0.21 0.94\n2012-13 * Stelmet Zielona Gora P-TBL 26 3 0 0 0 0 0 0 .054 0.79 0.57 0.13 17 9 .654 0.36 -0.01 0.35\n2012-13 * BC Anwil P-TBL 12 4 0 0 0 0 0 0 .072 1.00 0.75 0.06 8 4 .667 0.49 0.23 0.72\n2012-13 * Stelmet Zielona Gora Eurocup 6 2 0 0 0 0 0 0 .062 1.67 0.67 0.09 3 3 .500 -0.14 -0.05 -0.19\n2013-14 Asseco Prokom Gdynia P-TBL 36 35 0 0 0 0 0 0 .133 0.68 0.68 0.09 19 17 .528 0.92 1.17 2.09\n2014-15 Energa Czarni Slupsk P-TBL 28 1 0 0 0 0 0 0 .031 0.67 0.83 0.16 18 10 .643 0.15 0.23 0.39\n2015-16 Energa Czarni Slupsk P-TBL 41 33 0 0 0 0 0 0 .103 0.69 1.00 0.09 28 13 .683 2.11 0.78 2.89\n2016-17 Energa Czarni Slupsk P-TBL 38 27 0 0 0 0 0 0 .068 0.81 1.14 0.09 19 19 .500 0.46 0.72 1.18\n2017-18 Energa Czarni Slupsk P-TBL 19 18 0 0 0 0 0 0 .107 1.62 0.88 0.07 5 14 .263 0.24 0.08 0.32\n2009-10 Asseco Prokom Gdynia Euroleague 7 0 1.000 1.000 0.00 12.56 6.68 6.21 0.00 0.00 0.00 11.45 138.10 2.15 2.00 198.1 118.1 20.62\n2011-12 * All Teams All Leagues 45 24 .614 .608 1.43 5.08 3.30 6.12 8.72 1.50 0.14 15.19 158.85 -0.53 1.26 117.4 106.8 10.98\n2011-12 * Asseco Prokom Gdynia P-TBL 21 12 .605 .593 1.54 6.62 4.21 6.62 9.01 1.50 0.30 14.70 157.44 -0.10 1.28 118.4 106.0 11.46\n2011-12 * Asseco Prokom Gdynia VTB United 14 6 .651 .651 0.00 3.94 2.08 6.74 11.27 1.43 0.00 15.08 93.45 -1.14 1.30 118.6 105.5 12.00\n2011-12 * Asseco Prokom Gdynia Euroleague 10 6 .578 .578 3.35 2.91 3.15 3.23 4.26 1.59 0.00 16.51 79.06 -0.47 1.16 113.2 110.5 0.00\n2012-13 * All Teams All Leagues 44 9 .647 .642 0.91 5.56 3.26 5.61 14.76 1.22 0.36 11.87 156.47 -1.33 1.35 113.9 112.5 7.81\n2012-13 * Stelmet Zielona Gora P-TBL 26 3 .666 .656 0.79 3.62 2.20 5.24 17.83 1.30 0.00 11.37 165.85 -1.98 1.41 111.3 114.4 7.75\n2012-13 * BC Anwil P-TBL 12 4 .782 .788 0.81 7.98 4.59 4.78 10.56 1.06 1.27 11.85 159.43 -0.86 1.61 138.3 103.8 13.51\n2012-13 * Stelmet Zielona Gora Eurocup 6 2 .393 .386 1.57 8.12 4.79 7.76 11.59 1.17 0.00 13.69 106.68 0.35 0.82 84.7 121.7 3.67\n2013-14 Asseco Prokom Gdynia P-TBL 36 35 .564 .560 2.20 6.35 4.31 4.24 11.31 1.35 0.33 15.40 138.91 -1.97 1.17 106.1 105.8 9.71\n2014-15 Energa Czarni Slupsk P-TBL 28 1 .512 .484 2.31 5.54 3.99 2.29 8.40 0.99 0.00 12.47 149.12 -1.23 1.10 104.4 109.2 5.47\n2015-16 Energa Czarni Slupsk P-TBL 41 33 .621 .609 2.13 6.17 4.21 3.30 9.80 1.51 0.33 13.35 166.10 -1.47 1.29 118.6 104.5 11.22\n2016-17 Energa Czarni Slupsk P-TBL 38 27 .590 .585 1.45 4.22 2.85 4.09 13.56 1.89 0.40 10.81 145.31 -1.39 1.22 105.8 106.6 7.28\n2017-18 Energa Czarni Slupsk P-TBL 19 18 .536 .531 1.00 4.01 2.45 5.17 6.37 0.85 0.22 13.38 137.85 0.15 1.11 107.6 117.5 7.20\nMore Lukasz Seweryn International Stats »\nSep 13, 2013 - Lukasz Seweryn has signed with Asseco Prokom Gdynia.\nJul 21, 2014 - Lukasz Seweryn has signed with Energa Czarni Slupsk.


M e c a n is m o s d e d e fe n s a d e l\nC lic k to e d it M a s te r s u b title s ty le\nC a p í tu lo 1 5\nP r e s e n ta d o p o r : P r o f. C la r a L . C a m a c h o\nP r e p a r a d o p o r :D r a . N o e m í S o t o N ie v e s\nS is tem a inm une\nC ie n c ia q u e e s tu d ia la s r e s p u e s ta s\nin m u n e s c o n tr a s u s ta n c ia s e x tr a ñ a s y\nc o m o e s a s r e s p u e s ta s te a y u d a n a\nr e s is tir u n a in fe c c ió n\nC o m p u e s to d e c é lu la s , te jid o s , y\nó r g a n o s d is tr ib u id o s e n to d o e l c u e r p o\nR e c o n o c e s u s ta n c ia s e x tr a ñ a s o\nm ic r o o r g a n is m o s y lo s n e u tr a liz a o lo s\nd e s tr u y e\n◦ P o d e m o s d u r a r ta n to s a ñ o s p o r q u e\ne s ta m o s p r o te g id o s\nR es pues ta s inm unes\nM e c a n is m o s d e d e fe n s a h o s p e d e r a –\nm a n e r a s e n la s c u a le s e l c u e r p o n o s p r o te g e\nd e p a tó g e n o s .\nS o n d e fe n s a s fí s ic a s , q u í m ic a s o c e lu la r e s\nd e l c u e r p o e n c o n tr a d e :\n•m ic r o o r g a n is m o s p a tó g e n o s (v ir u s ,\nb a c te r ia s , h o n g o s , p a r á s ito s , y p r o to z o a r io s )\n•c é lu la s d e tu m o r\n•d a ñ o d e te jid o s\no tr o m a te r ia l e x tr a ñ o a l c u e r p o\nT r e s lí n e a s d e d e fe n s a\n1 r a lí n e a – n o e s p e c ific a\n2 d a lí n e a - n o e s p e c ific a\n3 r a lí n e a - e s p e c ific a\nF ig u r a 1 5 .1\nF ig u r a 1 5 .2\nM e c a n is m o s d e d e fe n s a h o s p e d e r a n o\ne s p e c ific a .\nD e f. – s o n g e n e r a le s y s ir v e n p a r a p r o te g e r e l\nc u e r p o c o n tr a m u c h a s s u b s ta n c ia s\np e r ju d ic ia le s .\nIn n a ta – r e s is te n c ia n a tu r a l a c ie r ta s\ne n fe r m e d a d e s\nT o d o e l tie m p o e s ta m o s e x p u e s to s a\np a tó g e n o s p o te n c ia le s y n u e s tr o c u e r p o lo s\nL o s m e c a n is m o s q u e s e v a n a\nd is c u tir :\nB a r r e r a s m e c á n ic a s y fí s ic a s a la\nin v a s ió n\nF a c to r e s q u í m ic o s\nA n ta g o n is m o s m ic r o b ia le s\nF ie b r e\nR e s p u e s ta s in fla m a to r ia s\nC é lu la s b la n c o s (fa g o c ito s is )\n1 r a lí n e a d e d e fe n s a s\nM e m b r a n a d e la p ie l y m u c o s a\n(b a r r e r a s fí s ic a s )\nP ie l (p r o te g e d e p a tó g e n o s )\n P o c o s o r g a n is m o s p u e d e n p e n e tr a r la p ie l\n(in fe c c io n e s d e h e lm in to s )\n L a s b a c te r ia s n o p u e d e n p e n e tr a r la p ie l\n L o s p a tó g e n o s p u e d e n p a s a r s i la p ie l s e c o r ta\no s e r a s p a . “C o m o q u ie r a e s d ifí c il”\nM e m b r a n a d e la p ie l y m u c o s a\nF a c to r e s c e lu la r e s y q u í m ic o s\n◦ L a p ie l e s s e c a , p H a c id ic o y la\nte m p e r a tu r a (<3 7 ˚ )\n G lá n d u la s s e b á c e a s p r o d u c e n “o ily s e b u m ” e l\nc u a l e s to x ic o p a r a lo s p a tó g e n o s .\n “P e r s p ir a c io n ” – r e m u e v e lo s o r g a n is m o s .\nT ie n e u n a s e n z im a s “lis o z im a s ” q u e d e g r a d a n\ne l p e p tid o g lu c a n o .\n E n z im a la c to fe r r in a – e n la z a n a l h ie r r o\n(n e c e s a r io p a r a lo s p a tó g e n o s )\n E n z im a la c to p e r o x id a s a – r a d ic a l d e\ns u p e r o x id o , in h ib e e l c r e c im ie n to b a c te r ia n o .\n◦ S is te m a r e s p ir a to r io\n P e lo s y m u c o s a s d e la n a r iz – s ir v e n p a r a\na t r a p a r p a tó g e n o s\n L o s c ilio s d e la s c é lu la s e p ite lia le s d e la\nm e m b r a n a s n a s a le s p o s te r io r e s . “m e m b r a n a s\nn a s a le s , b r o n q u io s y la tr á q u e a . L o s p a tó g e n o s\np u e d e n s e r tr a g a d o s o d e s c a r ta d o s d u r a n te le\nS is tem a R es pira to rio\nFa c tores de\nprotec c ión\nM e m b ra n a s\nC á m a ra s\nir r e g u la r e s d e la\nS is te m a m u c o c ilia r\n◦ L a s s e c r e c io n e s n a s a le s , s a liv a y\nla g r im a s c o n tie n e n liz o z im a s .\n◦ N o s o tr o s tr a g a m o s a p r o x im a d a m e n te 1 L\nd e s a liv a a l d í a\n◦ S is te m a d ig e s tiv o\n E n z im a s d ig e s tiv a s\n A c id e z e s to m a c a l (p H 1 .5 )\n A lc a lin id a d in te s tin a l\n 5 0 % d e la s h e c e s fe c a le s s o n b a c te r ia s\nV í a u r in a r ia s – s o n lib r e s d e p a tó g e n o s .\n(s a lu d a b le s )\nG a s tro intes tina l\ne s tó m a g o In te s tin o g r u e s o\n Á c id o s g á s tr ic o s  F lo r a n o r m a l\nin te s tin o s  R e m o c ió n d e\n E n z im a s c é lu la s\np a n c r e á tic a s s u p e r fic ia le s\n B ilis  L iz o z im a s y o tr o s\n E n z im a s c o m p u e s to s\nin te s tin a le s q u í m ic o s\n P e r is ta ls is\nC o p y r ig h t © T h e M c G r a w -H ill C o m p a n ie s , In c . P e r m is s io n r e q u ir e d fo r\nr e p r o d u c tio n o r d is p la y .\nS is tem a g enito urina rio\nA m b ie n te n o fa v o r a b le\n B a jo p H d e o r in a y v e g in a\n P r o d u c to s tó x ic o s e n la o r in a (E j.\nU re a )\n N a tu r a le z a h ip e r tó n ic a d e la m é d u la\nd e l r iñ ó n\n O r in a r fr e c u e n te m e n te y e x p u ls ió n d e\ns e c r e c io n e s d e m u c o s id a d e s\nA n ta g o n is m o s m ic r o b ia n o s\nL a m ic r o flo r a e n d ó g e n a p r o v ie n e la\nc o lo n iz a c ió n p o r n u e v o s p a tó g e n o s .\nE s to s e a tr ib u y e a :\n◦ C o m p e te n c ia p o r la c o lo n iz a c ió n\nC o m p e te n c ia p o r n u tr ie n te s\n◦ P r o d u c c ió n d e s u b s ta n c ia s q u e m a ta n\no tr a s b a c te r ia s .\nE l to m a r a n tib ió tic o s r e d u c e la flo r a\nm ic r o e n d ó g e n a .\n2 d a lí n e a d e d e fe n s a\nS i p e n e tr a n la 1 r a lí n e a d e d e fe n s a\ne n to n c e s la 2 d a lí n e a r e s p o n d e .\nR e s p u e s ta q u í m ic a y c e lu la r\nS e p r o d u c e n u n a s e r ie d e e v e n to s :\n◦ F ie b r e , p r o d u c c ió n d e in te r fe r o n ,\na c tiv a c ió n d e l s is te m a d e c o m p le m e n to ,\nin fla m a c ió n , q u im io ta x is y fa g o c ito s is .\nT r a n s fe r in a\nG lic o p r o te í n a s in te tiz a d a e n e l h í g a d o ,\ntie n e a lta a fin id a d p o r e l h ie r r o\n◦ T e m p e r a tu r a n o r m a l 3 6 .2 y 3 7 .5 ˚ (9 7 .2\ny 9 9 .5 ˚ ) F\nT e m p p r o m e d io 3 7 ˚ (9 8 .6 ˚ )\n◦ S i e s m a y o r d e 3 7 .8 ˚ (1 0 0 ˚ ) h a y fie b r e\nL a s s u s ta n c ia s q u e e s tim u la n la fie b r e\ns o n lo s p ir ó g e n a s y s u b s ta n c ia s\np ir o g é n ic a s\nS i p r o v ie n e d e l e x te r io r – e n d o to x in a\nS i p r o v ie n e d e l in te r io r – in te r le u q u in a -1\n(IL -1 )\nA u m e n ta la d e fe n s a h o s p e d e r a d e la s\ns ig u ie n te s m a n e r a s :\n1. E s tim u la lo s le u c o c ito s b la n c o s p a r a q u e\nd e s t r u y a n lo s in v a s o r e s\n2. R e d u c e la d is p o n ib ilid a d d e h ie r r o e n e l\np la s m a s a n g u í n e o\n3. In d u c e la p r o d u c c ió n d e IL -1 . C a u s a la\np r o life r a c ió n , m a d u r a c ió n y a c tiv a c ió n d e\nlin fo c ito s\n In te r fe r o n\n◦ S o n p e q u e ñ a s p r o te í n a s a n tiv ir a le s\np r o d u c id a s p o r c é lu la s in fe c ta d a s p o r v ir u s\n◦ T r e s tip o s d e in te r fe r o n : a lfa (α), b e ta (β) y\ng a m m a (γ).\n◦ S o n in d u c id o s p o r d ife r e n te s e s tí m u lo s :\nv ir u s , tu m o r , b a c te r ia s y o tr a s c é lu la s\n◦ L a s c é lu la s B , m o n o c ito s y m a c r ó fa g o s\ns e c r e ta n in te r fe r o n α\n◦ F ib r o b la s to s y o tr a s c é lu la s s e c r e ta n\nin te r fe r o n β\n◦ L in fo c ito s T a c tiv a d o s y “n a tu r a l k ille r s ”\ns e c r e ta n in te r fe r o n γ\nS is te m a d e c o m p le m e n to\nG r u p o a p r o x im a d o d e 3 0 p r o te í n a s\nd ife r e n te s q u e s e e n c u e n tr a n e n p la s m a\ns a n g u ín e o\nC a s c a d a d e c o m p le m e n to – u n o s\nin te r a c c io n a n c o n o tr a s\nC o n s e c u e n c ia s d e a c tiv a c ió n d e\nc o m p le m e n to\n In ic ia c ió n y a m p lific a c ió n d e in fla m a c ió n\n A c t iv a c ió n d e fa g o c ito s\n L is is d e b a c te r ia s o o tr a s c é lu la s\n A u m e n to d e fa g o c ito s is p o r la s c é lu la s\nfa g o c it ic a s\nC ito q u in a s\nS o n m e d ia d o r e s q u í m ic o s q u e s o n\nlib e r a d o s d e d ife r e n te s tip o s d e c é lu la e n\ne l c u e rp o h u m a n o\nP e r m ite q u e la s c é lu la s s e c o m u n iq u e n\nIn fla m a c ió n\nU n a s e r ie d e e v e n to s q u e e n r e s p u e s ta a\nu n a h e r id a , ir r ita c ió n , in v a s ió n m ic r o b ia n a\no to x in a b a c te r ia n a\nE v e n to s q u e c a u s a n la in fla m a c ió n\n1. A u m e n to e n e l d iá m e tr o d e l c a p ila r\n2. A u m e n to e n la p e r m e a b ilid a d d e l c a p ila r\n3. P r o m u e v e la s a lid a d e le u c o c ito s\n◦ F u n c ió n\n L o c a liz a r la in fe c c ió n\n P r e v e n ir e l e s p a r c im ie n to m ic r o b ia n o\n N e u t r a liz a c u a lq u ie r to x in a\n A y u d a a r e p a r a r e l te jid o d a ñ a d o\nS í n to m a s d e in fla m a c ió n\n E n r o je c im ie n to\n C a lo r\n H in c h a z ó n\nI nfla m a c ión a g uda : los fa g oc itos y\nproteína s del c om plem ento va n des de los\nva s os s a ng uíneos a l tejido a fec ta do\nT ipo s de g ló bulo s\nbla nc o s\nN e u tr ó filo s : m á s a b u n d a n te , fa g o c ita n\nb a c te r ia s\n•E o s in ó filo s : s e c r e ta n e n z im a s q u e p e r fo r a n a\ng u s a n o s p a r a s í tic o s , e n v u e lto s e n a le r g ia s\n•B a s ó filo s y m a s to c ito s : n o s o n fa g o c í tic o s ,\nfa b r ic a n y s e c r e ta n s u s ta n c ia s q u í m ic a s q u e\na y u d a n a m a n te n e r la in fla m a c ió n d e s p u é s d e\nF a g o c ito s is\nF a g o c ito s – g ló b u lo s b la n c o s o le u c o c ito s\nF a g o c ito s is – c u a n d o u n fa g o c ito e n g o lfa\ne l m a te r ia l e x ó g e n o o e x tr a ñ o .\n N e u tr ó filo s y m a c r ó fa g o s – s o n lo s fa g o c ito s\nG r a n u lo c ito s :\n N e u tr ó filo s - fa g o c ito s\n E o s in ó filo s – fa g o c ito s . H a y c a n tid a d e s a lta s\ne n a le r g ia s e in fe c c io n e s c o n h e lm in to s\n B a s ó filo s – n o s o n fa g o c ito s . R e a c c io n e s a\na le r g ia s e in fla m a c io n e s .\nM a c r ó fa g o s – p r o v ie n e n d e lo s\nm o n o c ito s .\nE s tá n e n e l flu jo s a n g u í n e o y m ig r a n a la s\ná r e a s a fe c ta d a s\n◦ T ie n e n n o m b r e s d e p e n d ie n d o d e l lu g a r\nd o n d e s e e n c u e n tr e n .\nG ló b u lo s b la n c o s\nM a c r ó fa g o s : e n v u e lv e n\ny d ig ie r e n a g e n te s\ne x tr a ñ o s , lim p ia n te jid o s\nd a ñ a d o s , lo s\nm a c r ó fa g o s in m a d u r o s\nse conocen com o\nm o n o c ito s\n2 d a lí n e a d e d e fe n s a .\nP a s o s d e la fa g o c ito s is (T a b la 1 5 -1 )\n1. Q u im io ta x is\n2. E n la c e d e l fa g o c ito a la m a te r ia e x tr a ñ a\n3. In g e s tió n\n4. D ig e s tió n : s e d is u e lv e la m a te r ia e x tr a ñ a\nc o n e n z im a s d ig e s tiv a s c e lu la r e s\nV e r (T a b la 1 5 -2 )\nT A B L E 1 5 -1 F o u r S te p s in P h a g o c y to s is\nSTEP B R IE F D E S C R IP T IO N\n1 . C h e m o ta x is P h a g o c y te s a r e a ttr a c te d b y c h e m o ta c tic\na g e n ts to th e s ite w h e r e th e y a r e n e e d e d\n2 . A tta c h m e n t A p h a g o c y te a tta c h e s to a n o b je c t\n3 . In g e s tio n P s e u d o p o d ia s u r r o u n d th e o b je c t, a n d it\nis ta k e n in to th e c e ll\n4 . D ig e s tio n T h e o b je c t is b r o k e n d o w n a n d d is s o lv e d\nb y d ig e s tiv e e n z y m e s a n d o th e r\nm e c h a n is m s\nI nm uno lo g ía\nInmunidad se refiere a cómo un hospedero resiste\nuna enfermedad en particular\n Natural-mecanismos heredados que actúan en\n Primeras líneas de defensa que posees\ncomo barreras y respuestas inflamatorias no\n Carece de memoria inmunológica\n Las sustancias extrañas se convierten en\nantígenos que provocan una respuesta\nespecífica del sistema inmune\n Poseen memoria inmunológica\nM ec a nis m o s de defens a\ndel ho s pedero\nS is te m a in m u n o ló g ic o\nD e b e d e d ife r e n c ia r lo s u y o d e lo s n o\nD e s tr u ir lo q u e n o e s s u y o\nL a s c é lu la s s e d e r iv a n d e la m e d u la\n◦ L in fo c ito s T\nC é lu la s a s e s in a s n a tu r a le s\nD o s tip o s d e c é lu la s T\nC é lu la s a y u d a n te s : T H (C D 4 )\nC é lu la m e d ia d o r a d e r e s p u e s ta in m u n e\nS e g r e g a c ito q u in a s q u e a c tiv a n lo s m a c r ó fa g o , c é lu la s\nc ito tó x ic a s y c é lu la s a s e s in a s n a tu r a le s .\nR e s p u e s ta h u m o r a l\nIn d u c e la a c tiv a c ió n d e c é lu la s B\nC é lu la s c ito tó x ic a s (C D 8 )\n D e s tr u c c ió n d e c é lu la s in fe c ta d a s p o r v ir u s\nF ig u r a 1 6 -1\nIn m u n id a d – c o n d ic ió n e n la c u a l s e\ne s in m u n e o r e s is te n te a u n a\ne n fe r m e d a d in fe c c io s a p a r tic u la r\nE je m p lo : h u m a n o s n o n o s c o n ta g ia m o s\nc o n c ie r ta s e n fe r m e d a d e s d e la s\nIn m u n id a d a d q u ir id a – r e s u lta e n la\np r o d u c c ió n a c tiv a o a d q u ir id a d e\na n tic u e r p o s d e p o r v id a .\nIn m u n id a d a d q u ir id a\nIn m u n id a d a d q u ir id a a c tiv a –\na n tic u e r p o s p r o d u c id o s e n e l c u e r p o\nd e la p e r s o n a\nIn m u n id a d a d q u ir id a p a s iv a – la\np e r s o n a r e c ib e a n tic u e r p o s\np r o d u c id o s p o r o tr a p e r s o n a o p o r\nm a s d e u n a p e rs o n a\nT A B L E 1 6 -1 T y p e s o f A c q u ir e d Im m u n ity\nA c tive a c quired im m unity N a tu r a l a c tiv e a c q u ir e d im m u n ity Im m u n ity th a t is a c q u ir e d in r e s p o n s e to\nth e e n tr y o f a liv e p a th o g e n in to th e b o d y\n(i.e ., in r e s p o n s e to a n a c tu a l in fe c tio n )\nA r tific ia l a c tiv e a c q u ir e d im m u n ity Im m u n ity th a t is a c q u ir e d in r e s p o n s e to\nv a c c in e s\nP a s s ive a c quired im m unity N a tu r a l p a s s iv e a c q u ir e d im m u n ity Im m u n ity th a t is a c q u ir e d b y a fe tu s w h e n\nit r e c e iv e s m a te r n a l a n tib o d ie s in u te r o o r\nb y a n in fa n t w h e n it r e c e iv e s m a te r n a l\na n tib o d ie s c o n ta in e d in c o lo s tr u m\nA r tific ia l p a s s iv e a c q u ir e d im m u n ity Im m u n ity th a t is a c q u ir e d w h e n a p e r s o n\nr e c e iv e s a n tib o d ie s c o n ta in e d in a n tis e r a\no r g a m m a g lo b u lin\nV a c u n a s – s e d e fin e c o m o m a te r ia l\nq u e p u e d e in d u c ir in m u n id a d a r tific ia l\na e n fe r m e d a d e s in fe c c io s a s ,\nu s u a lm e n te d e s p u é s d e u n a\nin y e c c ió n .\nT A B L E 1 6 -2 T y p e s o f A v a ila b le V a c c in e s\nT Y P E O F V A C C IN E EXAM PLES\nA tte nua ted va c c ines . T h e p r o c e s s o f w e a k e n in g p a th o g e n s is A ttenua ted vira l va c c ine s : a d e n o v ir u s , c h ic k e n p o x\nc a lle d a t t e n u a t io n , a n d th e v a c c in e s a r e r e f e r r e d to a s attenuated (v a r ic e lla ), m e a s le s (r u b e o la ), m u m p s , G e r m a n m e a s le s\nvaccines. M o s t liv e v a c c in e s a r e a v ir u le n t (n o n p a th o g e n ic ) m u ta n t (r u b e lla ), p o lio (o r a l S a b in v a c c in e ), r o t a v ir u s , s m a llp o x ,\ns t r a in s o f p a th o g e n s th a t h a v e b e e n d e r iv e d f r o m th e v ir u le n t y e llo w f e v e r\n(p a t h o g e n ic ) o r g a n is m s ; th is is a c c o m p lis h e d b y g r o w in g th e m f o r m a n y A ttenua ted ba c teria l va c c ines : B C G (f o r p r o t e c t io n\ng e n e r a tio n s u n d e r v a r io u s c o n d itio n s o r b y e x p o s in g th e m to m u ta g e n ic a g a in s t tu b e r c u lo s is ), c h o le r a , t u la r e m ia , ty p h o id f e v e r\nc h e m ic a ls o r r a d ia tio n . A tte n u a te d v a c c in e s s h o u ld n o t b e a d m in is te r e d (o r a l v a c c in e )\nto im m u n s u p p r e s s e d in d iv id u a ls , b e c a u s e e v e n w e a k e n e d p a th o g e n s\nc o u ld c a u s e d is e a s e in th e s e p e r s o n s .\nI na c tiva ted va c c ines . V a c c in e s m a d e f r o m p a th o g e n s th a t h a v e I na c tiva ted virus e s o r vira l a ntig ens : h e p a t it is A ,\nb e e n k ille d b y h e a t o r c h e m ic a ls — c a lle d inactivated vaccines— c a n b e in f lu e n z a , J a p a n e s e e n c e p h a lit is , o th e r (E E E , W E E ,\np r o d u c e d f a s te r a n d m o r e e a s ily , b u t th e y a r e le s s e f f e c tiv e th a n liv e R u s s ia n ) e n c e p h a lit is v a c c in e s , p o lio (s u b c u t a n e o u s S a lk\nv a c c in e s . T h is is b e c a u s e th e a n tig e n s o n th e d e a d c e lls a r e u s u a lly v a c c in e ), r a b ie s\nle s s e f f e c t iv e a n d p r o d u c e a s h o r te r p e r io d o f im m u n ity . I na c tiva ted ba c te ria l va c c ines : a n t h r a x , ty p h o id\nf e v e r (s u b c u ta n e o u s v a c c in e ), Q f e v e r\nS ubunit va c c ine s . A subunit vaccine (o r acellular vaccine) is o n e H e p a titis B , L y m e d is e a s e , w h o o p in g c o u g h\nth a t u s e s a n tig e n ic (a n tib o d y -s tim u la tin g ) p o r tio n s o f a p a th o g e n , r a th e r\nth a n u s in g t h e w h o le p a th o g e n . F o r e x a m p le , a v a c c in e c o n ta in in g p ili\no f Neisseria gonorrhoeae c o u ld th e o r e tic a lly s tim u la te th e b o d y to\np r o d u c e a n tib o d ie s th a t w o u ld a tta c h to N. gonorrhoeae p ili, th u s\np r e v e n t in g t h e b a c t e r ia fr o m a d h e r in g to c e lls . If N. gonorrhoeae c a n n o t\na d h e r e t o c e lls t h a t lin e th e u r e th r a , th e y c a n n o t c a u s e u r e th r itis . T h e\nm a t e r ia l t h a t is u s e d to p r o te c t h e a lth c a r e w o r k e r s a n d o th e r s f r o m\nh e p a t itis c a u s e d b y h e p a titis B v ir u s (H B V ) is b e in g p r o d u c e d b y\ng e n e tic a lly e n g in e e r e d y e a s ts . T h e g e n e s th a t c o d e f o r h e p a titis B\ns u r f a c e p r o te in w e r e in tr o d u c e d in to y e a s t c e lls , w h ic h th e n p r o d u c e d\nla r g e q u a n titie s o f t h a t p r o te in . T h e p r o te in s a r e th e n in je c te d in to\np e o p le . A n t ib o d ie s a g a in s t th e p r o te in a r e p r o d u c e d in th e ir b o d ie s , a n d\nth e s e a n t ib o d ie s s e r v e to p r o te c t th e p e o p le f r o m H B V h e p a titis .\nC o njug a te va c c ine s . S u c c e s s f u l c o n ju g a te v a c c in e s h a v e b e e n H ib (f o r p r o te c tio n a g a in s t Haemophilus influenzae ty p e\nm a d e b y c o n ju g a t in g b a c te r ia l c a p s u la r a n tig e n s (w h ic h b y th e m s e lv e s b ), m e n in g o c o c c a l m e n in g it is (Neisseria meningitidis\na r e n o t v e r y a n tig e n ic ) to m o le c u le s th a t s tim u la te th e im m u n e s y s te m s e r o g r o u p C ), p n e u m o c o c c a l p n e u m o n ia\nto p r o d u c e a n t ib o d ie s a g a in s t th e le s s a n tig e n ic c a p s u la r a n tig e n s .\nT o x o id va c c ines . A toxoid is a n e x o to x in th a t h a s b e e n in a c tiv a te d D ip h th e r ia , te ta n u s . C o m m e r c ia l a n tis e r a c o n ta in in g\n(m a d e n o n t o x ic ) b y h e a t o r c h e m ic a ls . T o x o id s c a n b e in je c te d s a f e ly to a n tito x in s a r e u s e d t o t r e a t d is e a s e s s u c h a s te t a n u s a n d\ns t im u la te t h e p r o d u c tio n o f a n tib o d ie s th a t a r e c a p a b le o f n e u tr a liz in g b o tu lis m . S u c h a n tis e r a a r e a ls o u s e d in c e r ta in ty p e s o f\nth e e x o to x in s o f p a th o g e n s , s u c h a s th o s e th a t c a u s e te ta n u s , b o tu lis m , la b o r a to r y te s ts , k n o w n a s im m u n o d ia g n o s t ic p r o c e d u r e s .\na n d d ip h t h e r ia . A n t ib o d ie s th a t n e u tr a liz e to x in s a r e c a lle d antitoxins ,\na n d a s e r u m c o n ta in in g s u c h a n tito x in s is r e f e r r e d to a s a n antiserum.\nD N A va c c ines . C u r r e n tly , D NA vaccines o r gene vaccines a r e o n ly L a b o r a to r y a n im a ls h a v e b e e n s u c c e s s f u lly p r o t e c t e d\ne x p e r im e n ta l. A p a r tic u la r g e n e f r o m a p a th o g e n is in s e r te d in to u s in g th is te c h n iq u e , a n d r e p o r t s o f t h e in d u c tio n o f\np la s m id s , a n d th e p la s m id s a r e th e n in je c te d in to s k in o r m u s c le tis s u e . c e llu la r im m u n e r e s p o n s e s in h u m a n s to a m a la r ia l\nIn s id e h o s t c e lls , t h e g e n e s d ir e c t th e s y n th e s is o f a p a r tic u la r m ic r o b ia l p a r a s ite a n tig e n , u s in g D N A v a c c in e s , h a v e b e e n\np r o t e in (a n t ig e n ). O n c e th e c e lls s ta r t c h u r n in g o u t c o p ie s o f th e p r o te in , p u b lis h e d .\nth e b o d y th e n p r o d u c e s a n tib o d ie s d ir e c te d a g a in s t th e p r o te in , a n d\nth e s e a n t ib o d ie s p r o te c t th e p e r s o n f r o m in f e c tio n w ith th e p a th o g e n .\nA uto g eno us va c c ine s . A n autogenous vaccine is o n e th a t h a s\nb e e n p r e p a r e d f r o m b a c te r ia is o la te d f r o m a lo c a liz e d in f e c tio n , s u c h a s\na s t a p h y lo c o c c a l b o il. T h e p a th o g e n s a r e k ille d a n d th e n in je c te d in to\nth e s a m e p e r s o n t o in d u c e p r o d u c tio n o f m o r e a n tib o d ie s .\nIn m u n id a d p a s iv a a d q u ir id a\nA n tic u e r p o s tr a n s m itid o s a u n a\np e r s o n a . C o m o la p e r s o n a n o lo s\np ro d u c e d u ra n d e 3 a 6 s e m a n a s\na . In m u n id a d a d q u ir id a p a s iv a n a tu r a l\n◦ P a s a d e la m a m a a l fe to\na . In m u n id a d a d q u ir id a p a s iv a a d q u ir id a\n◦ P a s a d e u n a p e r s o n a in m u n e a u n a\np e r s o n a s u s c e p tib le\nA n tí g e n o s – s u s ta n c ia s e x tr a ñ a s q u e\ns o n lo s u fic ie n te m e n te g r a n d e s p a r a\ne s tim u la r la p r o d u c c ió n d e\na n tic u e r p o s .\nA n tig é n ic o – s u b s ta n c ia c a p a z d e\ne s tim u la r la p r o d u c c ió n d e a n tic u e r p o s\nE j. A n tí g e n o s (p o lis a c á r id o s , m o lé c u la s\ng r a n d e s d e D N A o R N A , c o m b in a c ió n d e\nm o lé c u la s b io q u í m ic a s )\nA n tic u e r p o s – p r o te í n a s p r o d u c id a s\np o r lin fo c ito s e n r e s p u e s ta a la\np r e s e n c ia d e a n tí g e n o\nL a s b a c te r ia s p u e d e n e s tim u la r la\nfo r m a c ió n d e a n tic u e r p o s : m e m b r a n a\nc é lu la s , p a r e d c e lu la r , c a p s u la , fla g e lo ,\ne tc ..\nL o s a n tic u e r p o s s e c o n o c e n c o m o\nin m u n o g lo b u lin a s\nG lic o p r o te í n a s g lo b u la r e s e n la s a n g r e\nq u e p a r tic ip a s d e la s r e a c c ió n in m u n e .\nP o d e m o s e n c o n tr a r lo s e n lin fa , la g r im a s ,\ns a liv a , e tc .\nR e s p u e s ta p r im a r ia – r e s p u e s ta\nin m u n e in ic ia l a u n a n tí g e n o p a r tic u la r\nA p r o x im a d a m e n te d e 1 0 a 1 4 d í a s\n◦ D e s tr u y e e l a n tí g e n o y p a r te s e q u e d a\nc o m o lin fo c ito s d e m e m o r ia\nS i v e m o s e l a n tí g e n o n u e v a m e n te la s\nc é lu la s B d e m e m o r ia p r o d u c e n\na n tic u e r p o s\nR e s p u e s ta s e c u n d a r ia - a u m e n to e n la\np r o d u c c ió n d e a n tic u e r p o d e b id o a\nu n a s e g u n d a e x p o s ic ió n c o n e l\na n tí g e n o\nM em o ria inm uno ló g ic a\n¿ D ó n d e o c u r r e la r e s p u e s ta ?\nB a z o , n ó d u lo s lin fá tic o s u o tr a s á r e a s .\nE s tr u c tu r a d e l a n tic u e r p o\nT ie n e fo r m a d e Y\n◦ D o s c a d e n a s p e s a d a y d o s liv ia n a s\nu n id a s p o r e n la c e s d is u lfú r ic o s\nH a y 5 c la s e s d e a n tic u e r p o s :\n◦ Ig A , Ig D , Ig E , Ig G y Ig M\nF o r m a c ió n d e l c o m p le jo a n tí g e n o -\na n tic u e r p o\nIn m u n id a d m e d ia d a\nc e lu la r m e n te\nR a z ó n – lo s a n tic u e r p o s n o p u e d e n\np e n e tr a r la s c é lu la s\nH a y u n m e c a n is m o q u e c o n tr o la la s\nin fe c c io n e s in te r n a s\nM e c a n is m o s d e in te r a c c io n e s d e\nm u c h o s tip o s d e c é lu la s y s e c r e c io n e s\nc e lu la r e s (c ito q u in a s )\nL a s c é lu la s q u e p a r tic ip a n :\nm a c r ó fa g o , T H , T c , c é lu la s a s e s in a s y\ng r a n u lo c ito s\n1 . E l m a c r ó fa g o e n g o lfa y d ig ie r e\np a r c ia lm e n te e l p a tó g e n o . L o s\nfr a g m e n to s s e p r e s e n ta n e n la\ns u p e r fic ie d e l m a c r ó fa g o\n2 . T H s e e n la z a a l d e te r m in a n te\na n tig é n ic o e n la s u p e r fic ie d e l\nm a c r ó fa g o y p r o d u c e c ito q u in a s .\nE s ta s a c tiv a n la s c é lu la s e fe c to r a s\nT c y a s e s in a s\n3. L a s c é lu la s e fe c to r a s lib e r a n e l\nc o n te n id o d e s u s v e s í c u la s .\nIn c lu y e n d o p e r fo r in a y o tr a s\ns u s ta n c ia s q u e h a c e n h u e c o s e n la\nm e m b r a n a d e la c é lu la in fe c ta d a .\nL ib e r a n c ito q u in a s\n4 . L a s to x in a s lib e r a d a s p o r la s c é lu la s\ne fe c to r a s a la s c é lu la s in fe c ta d a s\nr o m p e n e l D N A y lo s o r g a n e lo s\nc a u s a n d o la m u e r te d e la c é lu la\nC élula s del S is tem a\nI nm uno ló g ic o\n•C élula pres enta do ra de\na ntíg eno : p r o c e s a n y e x h ib e n u n\na n tí g e n o y a c tiv a n c é lu la s T E j.\nM a c r ó fa g o s , c é lu la s B , c é lu la s\nd e n d r ita s\n•C élula s T a ux ilia res o\na yuda ntes : s e u n e n a lo s\nc o m p le jo s a n tí g e n o -M H C , p r o d u c e n\ns e ñ a le s q u e d ife r e n c ia n a c é lu la s B y\nT s e n s ib le s a l a n tí g e n o\nT ejido s y ó rg a no s\nN ó dulo s linfá tic o s :\n•S e e n c u e n tr a n a\nin te r v a lo s a lo la r g o d e\nlo s v a s o s lin fá tic o s\n•L le n o d e g ló b u lo s\nb la n c o s q u e d e s tr u y e n\nlo s p a tó g e n o s y r e s to s\nS is tem a I nm uno ló g ic o\n•A ntíg eno : c u a lq u ie r c o n fig u r a c ió n m o le c u la r\nq u e e s r e c o n o c id o p o r lo s g ló b u lo s b la n c o s\nc o m o n o p r o p io s y q u e d e s e n c a d e n a n u n a\nr e s p u e s ta in m u n e E j. p r o te in a s e n la s\ns u p e r fic ie d e c é lu la s d e tu m o r e s o p a tó g e n o s\n•M a rc a do res M H C (c o m p le jo m a y o r d e\nh is to c o m p a tib ilid a d ): p r o te in a s d e\nr e c o n o c im ie n to u b ic a d a s e n la m e m b r a n a\np la s m á tic a d e la s c é lu la s d e l c u e r p o q u e s e\nu n e n a a n tí g e n o s


reisenthel ® allround er M barokke taupe | pinkorblue.nl\nProd. nr.: A296916\nOpening met rits en geïntegreerd Metal handvat\nWijzigingsvoorstel voor artikel A296916\nProductbeoordelingen van onze klanten: reisenthel ® allround er M barokke taupe


Danielle Alves Gomes Zauli (April 17th 2019). PCR and Infectious Diseases, Synthetic Biology - New Interdisciplinary Science, Madan L. Nagpal, Oana-Maria Boldura, Cornel Baltă and Shymaa Enany, IntechOpen, DOI: 10.5772/intechopen.85630. Available from:


SOUBRIER DE SUAREZ,,, FARRAS GUILLAMON, FR,\n1 5 -110 99.29% 8NS ALVAREZ VARELA, MARY, GARCIA MEDINA, M. DO,\n2 5 -150 90.71% 8NS ALVAREZ VARELA, MARY, GARCIA MEDINA, M. DO,\n3 5 -600 99.29% 8NS ALVAREZ VARELA, MARY, GARCIA MEDINA, M. DO,\n7 6 -690 90.71% 9NS ALVAREZ FERNANDEZ, M, RIONDA FERNANDEZ, AN,\n8 6 200 66.43% 9NS ALVAREZ FERNANDEZ, M, RIONDA FERNANDEZ, AN,\n9 6 -1430 90.71% 9NS ALVAREZ FERNANDEZ, M, RIONDA FERNANDEZ, AN,\n10 1 710 42.14% 4NS GONZALEZ GLEZ, ESTHE, GARCIA ORVIZ, ANA M.,\n11 1 -450 42.14% 4NS GONZALEZ GLEZ, ESTHE, GARCIA ORVIZ, ANA M.,\n12 1 690 9.29% 4NS GONZALEZ GLEZ, ESTHE, GARCIA ORVIZ, ANA M.,\n13 7 -140 42.86% 10NS ARCE SOLARES, AMPARO, LEAL FERNANDEZ, ANA,\n14 7 -170 14.29% 10NS ARCE SOLARES, AMPARO, LEAL FERNANDEZ, ANA,\n15 7 -420 28.57% 10NS ARCE SOLARES, AMPARO, LEAL FERNANDEZ, ANA,\n16 2 100 50.00% 5NS DIAZ SOLANO, Yoyo DIAZ SOLANO, ANA,\n17 2 -100 74.29% 5NS DIAZ SOLANO, Yoyo DIAZ SOLANO, ANA,\n18 2 90 82.86% 5NS DIAZ SOLANO, Yoyo DIAZ SOLANO, ANA,\n19 8 -230 85.71% 11NS NAVARRO PEREZ-PAVES,, MOLERO MANGLANO, CAR,\n20 8 -200 78.57% 11NS NAVARRO PEREZ-PAVES,, MOLERO MANGLANO, CAR,\n21 8 50 71.43% 11NS NAVARRO PEREZ-PAVES,, MOLERO MANGLANO, CAR,\n22 3 -650 82.86% 6NS RIERA, Esther ARG�ELLES CAMINO, NI,\n23 3 -100 66.43% 6NS RIERA, Esther ARG�ELLES CAMINO, NI,\n24 3 -400 99.29% 6NS RIERA, Esther ARG�ELLES CAMINO, NI,\n28 4 50 74.29% 7NS FDEZ. ESCANDON, Ana FERNANDEZ, Flor\n29 4 -720 17.14% 7NS FDEZ. ESCANDON, Ana FERNANDEZ, Flor\n30 4 420 17.14% 7NS FDEZ. ESCANDON, Ana FERNANDEZ, Flor


Fiesta Bakery in San Antonio, TX with Reviews - YP.com\nSan Antonio, TX Fiesta Bakery\n1. Fiesta Bakery\n3. Fiesta Bakery\n4. La Fiesta Bakery\n5. Fiesta Bakery 2 - CLOSED\n9. Hill Country Bakery\n10. Horno Mission San Jose Bakery\n11. Cupcake Couture-Broadway\n13. Dulce Landia Cakes\n14. Lone Star Bakery Inc\n15. Gourmet Cupcake Shop\n16. Lulus Catering - CLOSED\n17. El Volcan Panaderia\n18. Ruthies Bakery\n19. Sugarbakers Cafe & Bakery\n20. Infinity Cakes & More\n21. Trini Cakes Cupcakery\n22. Bunuelos-The Original Hemisfair Bunuelos\n25. Bistro Bakery\n26. Las Conchas Bakery\n29. Cuit Au Four\n30. Medina Base Cafe & Bakery - CLOSED


ID position 902292\n1. d4 d5 2. c4 e6 3. Nf3 Nf6 4. g3 Bb4 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3\n1. d4 Nf6 2. c4 e6 3. Nf3 d5 4. g3 Bb4 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3\n1. d4 Nf6 2. c4 e6 3. g3 d5 4. Nf3 Bb4 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3\n1. d4 Nf6 2. Nf3 d5 3. c4 e6 4. g3 Bb4 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3\n1. c4 Nf6 2. g3 e6 3. d4 Bb4 4. Bd2 Be7 5. Bg2 d5 6. Nf3 O-O 7. O-O c6 8. Bc3\n1. d4 Nf6 2. c4 e6 3. g3 Bb4 4. Bd2 Be7 5. Bg2 O-O 6. Nf3 d5 7. O-O c6 8. Bc3\n1. d4 Nf6 2. c4 e6 3. g3 Bb4 4. Bd2 Be7 5. Bg2 d5 6. Nf3 O-O 7. O-O c6 8. Bc3\n1. d4 Nf6 2. c4 e6 3. g3 d5 4. Bg2 Bb4 5. Bd2 Be7 6. Nf3 O-O 7. O-O c6 8. Bc3\n1. Nf3 Nf6 2. c4 e6 3. d4 d5 4. g3 Bb4 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3\n1. Nf3 d5 2. c4 e6 3. d4 Nf6 4. g3 Bb4 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3\nNbd7 3 37 5 62 0 0 8 72\nb6 1 33 1 33 1 33 3 27\nTotal 4 36 6 54 1 9 11\n14250456 1. d4 Nf6 2. c4 e6 3. Nf3 d5 4. g3 Bb4+ 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3 dxc4 9. a4 b6 10. Ne5 Ba6 11. Nd2 Nd5 12. Nexc4 Nd7 13. Qb3 Qc7 14. Rfd1 Rac8 15. e4 Nxc3 16. bxc3 Nf6 17. e5 Nd5 18. a5 Bxc4 19. Nxc4 b5 20. Nd2 Rb8 21. Ne4 1/2-1/2\n13896458 1. d4 Nf6 2. c4 e6 3. Nf3 d5 4. g3 Bb4+ 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3= Ne4 9. e3 b5 10. c5 a5 11. a3 Nd7 12. b4 f5 13. Bb2 Bb7 14. Nc3 Nxc3 15. Bxc3 a4 16. Ne5 Nxe5 17. dxe5 g5 18. f4 g4 19. h3 h5 20. hxg4 hxg4 21. Kf2 Kf7 22. Rh1= Rh8 23. Rxh8 Qxh8 24. Qd3 Rd8 25. Rh1 Qg7 26. Qd1 Rh8 27. Bd4 Kg8 28. Rxh8+ Qxh8 29. Qh1 Qxh1 30. Bxh1 Kf7 31. Bg2 1/2-1/2\nII Sharjah Masters 2018\n14062306 1. Nf3 Nf6 2. c4 e6 3. d4 d5 4. g3 Bb4+ 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3= Ne4 9. Nfd2 Nxc3 10. Nxc3 Nd7 11. e3 b6 12. Qa4 Bb7 13. a3 Qc7 14. Rfc1 dxc4 15. Nxc4 c5 16. d5 exd5 17. Nxd5 Bxd5 18. Bxd5 Rad8 19. Rd1 Bf6 20. Rd2 g6 21. Rad1 Kg7 22. f4 Nb8 23. Bf3 a6 24. Qc2 b5 25. Nd6 c4 26. e4 c3 27. e5 Qb6+ 28. Rf2= Be7 29. Qxc3 f6 30. Kg2 Bxd6 31. exd6 Rxd6 32. Rxd6 Qxd6 33. Rd2 Qe7 34. Qd4 Rc8 35. h4 Rc7 36. Qb6 Rd7 37. Re2 Qd8 38. h5 Qxb6 0-1\n14015827 1. d4 Nf6 2. c4 e6 3. g3 d5 4. Bg2 Bb4+ 5. Bd2 Be7 6. Nf3 O-O 7. O-O c6 8. Bc3 a5 9. Nbd2 b5 10. b3 Ba6 11. Ne5 Nfd7 12. Nd3 Ra7 13. Qc2 Qc7 14. a4 dxc4 15. bxc4 b4 16. Bb2 c5 17. Rac1 Rc8 18. d5 exd5 19. Bxd5 Bb7 20. e4 Bf6 21. Nb3 Bxd5 22. exd5 Qd6 23. Rfe1 h6 24. f4 Bxb2 25. Qxb2 Nb6 26. Ndxc5 N8d7 27. Ne4 Qb8 28. Qd4 Nxa4 29. c5 Naxc5 30. Nexc5 Nxc5 31. Rxc5 Rxc5 32. Nxc5 Qb6 33. d6 a4 34. Re8+ Kh7 35. Qe4+ 1-0\n14109312 1. d4 d5 2. c4 e6 3. Nf3 Nf6 4. g3 Bb4+ 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3 dxc4 9. Ne5 b5 10. Nxc6 Nxc6 11. Bxc6 Rb8 12. b4 a5 13. a3 axb4 14. axb4 Rb6 15. Bg2 Nd5 16. Bxd5 exd5 17. Nd2 Bh3 18. Re1 f5 19. f4 g5 20. e3 Bg4 21. Qc2 Re6 22. Nf1 Bf3 23. Ra5 Qe8 24. Qf2 Be4 25. Nd2 g4 26. Rea1 Bd8 27. R5a3 Bd3 28. Re1= Qc6 29. Nf1 Rfe8 30. Bd2 Bb6 31. Bc3 R8e7 32. Qd2 Qe8 33. Bb2 Be4 34. Qf2 Kg7 35. Qd2 Qd7 36. Bc3 Re8 37. Re2 Qe7 38. Re1 Kg8 39. Bb2 Bd3 40. Kf2 Re4 41. Ba1 h5 42. Bb2 h4 43. Ba1 Bc7 44. Bb2 Bd6 45. Bc3 Bxf1 46. Kxf1 Rxe3 47. Rxe3 Qxe3 48. Qxe3 Rxe3 49. Kf2 Rf3+ 50. Kg2 h3+ 51. Kg1 Kf7 52. Ra7+ Ke6 53. Be1 c3 54. Ra6 Kd7 55. Ra7+ Kc6 56. Ra6+ Kc7 57. Ra2 Bxb4 58. Rc2 Ba5 59. Bf2 Bb6 60. Kh1 b4 61. Bg1 b3 62. Rc1 b2 63. Re1 Kd7 64. Re2 b1=B 65. Re1 Be4 66. Rxe4 fxe4 67. f5 c2 68. f6 c1=Q 69. f7 Qxg1+ 70. Kxg1 Bxd4+ 0-1\n13465448 1. d4 Nf6 2. c4 e6 3. g3 Bb4+ 4. Bd2 Be7 5. Bg2 O-O 6. Nf3 d5 7. O-O c6 8. Bc3= Ne4 9. Nbd2 Nxc3 10. bxc3 Nd7 11. e4 dxe4 12. Nxe4 f5 13. Ned2 Bf6 14. Re1 Re8 15. c5 e5 16. Qb3+ Kh8 17. Nc4 e4 18. Nd6 Rf8 19. Nf7+ Rxf7 20. Qxf7 Qg8 21. Qxg8+ Kxg8 22. Nd2 b6 23. cxb6 axb6 24. a4 c5 25. Nb3 cxd4 26. cxd4 Bb7 27. a5= Bd5 28. axb6 Rb8 29. Nc5 Nxb6 30. Red1 Nc4 31. Nd7 Rd8 32. Nxf6+ gxf6 33. Ra7= Nb2 34. Rc1 Nc4 35. Bh3 Nd6 36. Rc5 Be6 37. Re7 Bf7 38. Rcc7 Rb8 39. Bxf5 Bd5 40. Be6+ 1-0\n1382222 1.d4 Nf6 2.c4 e6 3.g3 d5 4.Nf3 Bb4+ 5.Bd2 Be7 6.Bg2 O-O 7.O-O c6 8.Bc3 dxc4 9.Ne5 b5 10.Nxc6 Nxc6 11.Bxc6 Rb8 12.a3 a5 13.b4 axb4 14.Bxb4 Bxb4 15.axb4 Qd6 16.Bg2 Qxb4 17.Qc2 Qd6 18.e3 Bb7 19.Bxb7 Rxb7 20.Nd2 e5 21.Rfb1 Qc7 22.dxe5 Qxe5 23.Ra5 c3 24.Nf3= Qe4 25.Qxe4 Nxe4 26.Nd4 b4 27.Ra4 Rfb8 28.Nc6 c2 29.Re1 Nc3 30.Ra5 b3 31.Nxb8 Rxb8 32.Rc5 b2 0-1\nMakeev Niikolay (RUS)\nDemianjuk Alexander (RUS)\n709059 1. d4 Nf6 2. c4 e6 3. Nf3 d5 4. g3 Bb4+ 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3 dxc4 9. Ne5 b5 10. a4 Nd5 11. axb5 cxb5 12. Ba5 Qe8 13. b3 Nc6 14. bxc4 bxc4 15. Nxc6 Qxc6 16. e4 Nf6 17. d5 exd5 18. exd5 Qd6 19. Re1 Bg4 20. Qd4= Bd8 21. Qxc4 Bxa5 22. Rxa5 Rfe8 23. Rxe8+ Rxe8 24. h3 Rc8 25. Qd4 Rc1+ 26. Kh2 Rxb1 27. hxg4 Rb4 28. Qxa7 Nxg4+ 29. Kg1 Rb1+ 30. Bf1 h5 31. Qd4 Qb4 32. Qxb4 Rxb4 1/2-1/2\n3141518 1. d4 Nf6 2. c4 e6 3. g3 d5 4. Nf3 Bb4+ 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3 dxc4 9. Ne5 b5 10. a4 Nd5 11. axb5 cxb5 12. b3 Bb7 13. Ba5 Qc8 14. bxc4 bxc4 15. Qa4 Nc6 16. Nxc6 Qxc6 17. Qxc6 Bxc6 18. Rc1 Rfc8 19. e4 Nb4 20. Na3 Rab8 21. Rxc4 Ba8 22. h4 Rxc4 23. Nxc4 Nc2 24. Rd1 Rc8 25. d5 Rxc4 26. d6 Kf8 27. d7 Bxe4 28. Rb1 f5 29. Bxe4 Rxe4 30. Rb8+ Kf7 31. h5 Rd4 32. Rb7 Rd1+ 33. Kg2 Kf6 34. f4 e5 35. Rxa7 Ke6 36. d8=Q Bxd8 37. Bxd8 Rxd8 38. Rxg7 Rd7 0-1\n1288719 1. d4 Nf6 2. c4 e6 3. g3 Bb4+ 4. Bd2 Be7 5. Bg2 d5 6. Nf3 O-O 7. O-O c6 8. Bc3 dxc4 9. Ne5 b5 10. Bxc6 Nxc6 11. Nxc6 Qc7 12. Nxe7+ Qxe7 13. Ba5 Bb7 14. a3 e5 15. Nc3 Qd7 16. e3 Rfe8 17. f3 exd4 18. Qxd4 Qxd4 19. exd4 a6 20. Kf2 Re6 21. Rfe1 h5 22. Rxe6 fxe6 23. Re1 Rf8 24. f4 Kf7 25. h3 g6 26. Re5 Bd5 27. Rg5 Rc8 28. Ke3 Bg2 29. h4 Bd5 30. Kd2 Rc6 31. Bb4 Rc7 32. Ke2 Rd7 33. Bc5 Bc6 34. Bb6 Bd5 35. Ke3 Ng4+ 36. Ke2 Nh6 37. Re5 Bc6 38. Ne4 Bxe4 39. Rxe4 Ng4 40. Kf3 Nf6 41. Re5 Nd5 42. Ba5 Ne7 43. Bb6 Nc6 44. Re4 Kf6 45. g4 hxg4+ 46. Kxg4 Ne7 47. Ba5 Rd5 48. Re5 Nc6 49. Rxd5 exd5 50. Bd2 a5 51. Be1 b4 52. axb4 axb4 53. Bd2 c3 54. bxc3 b3 55. Bc1 Na5 56. f5 gxf5+ 57. Kf4 Nc4 58. h5 b2 59. Bxb2 Nxb2 60. h6 Na4 61. h7 Kg7 62. Kxf5 Nxc3 63. h8=Q+ Kxh8 64. Kf6 Kh7 65. Kf7 Kh6 66. Kf6 Kh5 67. Kf5 Kh4 68. Kf4 Kh3 69. Kf3 Kh2 70. Kf2 Nb5 0-1\nKayumov, Dmitry D\n295019 1. d4 Nf6 2. Nf3 d5 3. c4 e6 4. g3 Bb4+ 5. Bd2 Be7 6. Bg2 O-O 7. O-O c6 8. Bc3 dxc4 9. a4 b5 10. axb5 cxb5 11. Ba5 Qe8 12. Ne5 Nd5 13. b3 cxb3 14. Qxb3 Bb7 15. Nc3 Nxc3 16. Bxb7 Nxe2+ 17. Kg2 Nd7 18. Qe3 Nxd4 19. Qxd4 Nxe5 20. Qxe5 Bf6 21. Qe4 Bxa1 22. Rxa1 Rb8 23. Bc7 f5 24. Qf3 Rf7 25. Bc6 Rxc7 26. Bxe8 Rxe8 27. Qb3 Rb7 28. Ra5 a6 29. Rxa6 Kf7 30. Qf3 Reb8 31. Qc6 Re7 32. Rb6 Rxb6 33. Qxb6 b4 34. Qxb4 Rd7 35. Qh4 h6 36. Qh5+ Kf6 37. Qe8 Re7 38. Qf8+ Rf7 39. Qd8+ Re7 40. Kf3 Kf7 41. Kf4 Rb7 42. Qd3 Ra7 43. Qb5 Kf6 44. Qe8 Rc7 45. Qd8+ Re7 46. h3 e5+ 47. Ke3 h5 48. Qh8 Kg6 49. h4 Re6 50. Qf8 e4 51. Kf4 Rf6 52. Qe8+ 1-0\n1472221 1. d4 Nf6 2. c4 e6 3. g3 Bb4+ 4. Bd2 Be7 5. Bg2 d5 6. Nf3 O-O 7. O-O c6 8. Bc3 Ne4 9. Nbd2 Nxc3 10. bxc3 Nd7 11. Qc2 b5 12. cxb5 cxb5 13. Rfb1 Nb6 14. e4 Ba6 15. Bf1 Nc4 16. Nxc4 bxc4 17. Qa4 Bc8 18. Ne5 Qd6 19. Bg2 Rd8 20. Nc6 Rd7 21. Ne5 Rd8 22. exd5 exd5 23. Nxc4 Qc7 24. Ne3 Be6 25. c4 Rac8 26. Nxd5 Bxd5 27. Bxd5 Rb8 28. Rb3 Bf6 29. Rab1 Rxb3 30. Rxb3 Bxd4 31. Rb7 Qc5 32. Rxf7 Kh8 33. Qc2 Bf6 34. Qf5 Bd4 35. h4 Qc8 36. Qf4 Bc5 37. Rc7 1-0\nEgeli, Per Ove


328221772 NewKadia comic books ● 125 Noble St, 3rd floor ● Norristown, PA 19401610-277-3000 Monday - Friday, 10 am - 6 pm EST Sitemap XMONEY\n332490169 <", c, ' onload="var d=', n, ";d.getElementsByTagName('head').", d, "(d.", g, "('script')).", i, "='", a.l, "'\_">"].join("") } var c = "body", e = h[c]; if (!e) return setTimeout(q, 100); a.P(1); var d = "appendChild", g = "createElement",