For PROs this means a thorough revision of current approaches to scientific research, user needs and (lack of) critical mass: if a fair process of consultation does not lead to a main strategic objective, other solutions, including potential merger into a university, should be considered. Base this reform process on the NHEP and the RISS as it must include many aspects of the two strategy documents. A structured legal and organisational framework needs to be put in place in advance. Build interim evaluation and reporting systems into the transition to autonomy in order to ensure that the reforms produce the intended results.