Expectations about the contribution of STI have increased in recent years as fast-evolving technologies are rapidly changing the development landscape. They open new possibilities to address long-standing development challenges across the SDGs—from poverty and hunger, access to health care and education, to low-carbon energy, combatting climate change, and financial inclusion. They are also changing the development finance landscape, creating opportunities across the action areas of the Addis Ababa Action Agenda (hereafter, Addis Agenda).