This chapter frames the implementation of human rights law through global health governance. Global governance institutions have sought to translate human rights into public policy, shifting from the development of health-related rights under international law to the implementation of these normative standards in global policies, programs, and practices. This shift toward an “era of implementation” across an expanding global health governance landscape looks beyond the traditional “human rights system” in implementing human rights for global health. Analyzing human rights as part of global health law, this chapter examines how human rights have become a framework for global governance, with institutions of global health governance seeking to “mainstream” human rights across all organizational actions. This chapter concludes that there is a need for institutional analysis to compare organizational approaches conducive to the implementation of health-related human rights.