There are several programmes and initiatives which aim to strengthen patient safety work across the NHS: a network of 15 Patient Safety Coilaboratives, a Sign up to Safety Campaign, a Healthcare Safety Investigation Branch. Several specific programmes of safety work are also underway in the English NHS, including initiatives on pressure ulcers, antimicrobial resistance, mental health, etc. This is accompanied by an Indicators of Performance Direction, which sets out a range of performance indicators intended to improve Health and Social Care Trust performance.