reading his prematurely published obituary, Mark Twain famously quipped that rumors of his death were greatly exaggerated. Those of us who advance scholarship at the intersection of international security studies and biopolitics would amend Twain: any rumor of its acceptance has been greatly exaggerated. At the beginning of "the century of biology," when we reflect on the relationship between the discipline of international security studies and biopolitics, there are reasons for both hope and despair. In this commentary, I would like to explore those reasons and identify avenues of research at the nexus of biopolitics and international security studies.