The aim of this article is essentially to discuss the intersection between diplomacy and public health policies to combat and control tobacco use, stressing the importance of cooperation in global health to achieve the foundations for the Framework Convention on Tobacco Control (FCTC), the first internation­al treaty on health which was negotiated by the member countries of the World Health Assembly. The aim is also to evaluate the global health and the role of governance in international tobacco control as well to draw a link between the FCTC and diplomacy. It was concluded that health demands require a global commitment and the legislation establishing control of smoking appears as the first international measure included in a context of diplomacy in health and governance, aiming public policy-making for the promotion of global health.