The nexus of economic and political relations is a central issue in international relations, and the influence of political liberalization upon trade ties lies at the center of much liberal theory. However, many facets of the empirical linkage between political liberalization—including democratization and the respect for human rights—and trade remain uninvestigated. Examining the case of U.S.‐Africa trade, this study considers two unexplored facets of these political determinants of trade: (1) the role of human rights conditions, and (2) the robustness of the relationship between democracy, human rights, and trade across a subset of vertical dyads. Using a gravity model to assess trade patterns, we find that neither democracy nor human rights conditions has a significant impact upon U.S. trade to Africa.