The aim of this work is to add reflections regarding public health issues, as an ethical framework within the Universal Declaration on Bioethics and Human Rights, to social perspective of bioethics. It is a theoretical study methodologically organized in three sections: (1) Georgetown principles in the analysis of social dilemmas, (2) epistemological notion for social dimension of bioethics - principles of respect for human vulnerability, equity and social fairness, social responsibility and health, solidarity and cooperation, and (3) moral perspective facing unfavorable social contexts. The Declaration’s text may show as potentiality the formulation of a duty of moral action in face of contextual situations that weaken some society groups.