With regard to this, a framework may be strengthened to check the appropriateness of measures under IHR, and coordination may be pursued with actors in other sectors, such as WTO.10 The Sanitary and Phytosanitary (SPS) Agreement of WTO states that when national standards that are stricter than international standards are adopted, the national standards must be scientifically justified. For example, in the case in which Europe instituted trade restrictions during a cholera outbreak in Africa, the SPS Committee of WTO deliberated on the restrictions, including a scientific debate on the risk these measures pose to public health, which resulted in the trade restrictions being lifted (WHO and WTO, 2002). Collaboration with initiatives, such as the Global Health Security Agenda (GHSA), is already under way, including the joint external evaluation tool for IHR formulated by WHO with GHSA, a multilateral framework led by the United States, which has stated that it will achieve its goals in at least 30 countries over the next five years, and has declared that it will invest US$1 billion in 17 countries towards this effort.