As this report has shown, once children have navigated their way successfully through infancy and childhood, a new set of challenges awaits. Global challenges, including climate change, economic uncertainty, globalization, demographic shifts and humanitarian crises, present an uncertain backdrop for adolescents during the pivotal decade of their lives. A good start in life is necessary but not sufficient to break the bonds of poverty and inequity: To make a lasting difference, for both individuals and societies, support in early and middle childhood must be complemented by investment in adolescent education, health care, protection and participation - particularly for the poorest and most marginalized. Families, communities, national governments, donors, development agencies and all other stakeholders must join together with young people as they prepare for their future.