South African domestic law of jurisdiction informs the assumption of jurisdiction in cross-border commercial litigation. In regard to choice of court agreements, the fragmented nature of High Court jurisdiction and the common law rules relating to submission to jurisdiction present unique challenges. Two types of choice of court agreements can be identified in South African law: foreign exclusive choice of court agreements and optional choice of court agreements in favour of South African courts. It is submitted that the South African law relating to cross-border jurisdiction is in need of reform and this should be undertaken following an international and comparative approach, in keeping with the Constitution of the Republic of South Africa, 1996.