The decision to focus on technology transfer, interfaces, technology-based firms and start-ups was largely determined by a contemporary international drive to transfer best practices without much concern about their suitability to national settings (Todtling and Trippl, 2005) and had a formative influence on the future policy trajectory. In 2001, MoST established the Ministry of Crafts and Small and Medium Sized Enterprises (MOMSP) and HITRA, the Croatian Programme for Innovative Technological Development. These initiatives reflected a political intention to launch innovation and entrepreneurship. Its main task was ambitiously defined: to restructure the wider R&D sector to meet the requirements of the knowledge economy.