A relapse or recurrence is another potential outcome, in which case the treatment has to be re-established or modified. Sequelae, the negative consequences of a condition, can persist. Both an acute and a chronic condition may deteriorate, causing disability of some degree of severity, from mild to complete. A decline across several domains of functioning could leave the individual unable to handle their own care, and when rehabilitation is not feasible, a long-term care (HC.3) option is pursued. This aims to maintain the best quality of life and to reduce suffering and limit deterioration.