The aim is to improve reproductive and maternal and child health, end the epidemics of HIV/AIDS, malaria, tuberculosis and neglected tropical diseases, reduce non-communicable and environmental diseases, achieve universal health coverage, and ensure universal access to safe, affordable and effective medicines and vaccines. Towards that end, world leaders committed to support research and development, increase health financing, and strengthen the capacity of all countries to reduce and manage health risks. Almost all maternal deaths occur in low-resource settings and can be prevented, including by expanding access to appropriate sexual and reproductive health services.