MI
Using Brown Norway Katholiek (BNK) rats, which are deficient in kininogen (kinin        precursor) due to a mutation in the kininogen gene, we examined the role of       endogenous kinins in 1) normal cardiac function; 2) myocardial infarction (MI)       caused by coronary artery ligation; 3) cardiac remodeling in the development of       heart failure (HF) after MI; and 4) the cardioprotective effect of       angiotensin-converting enzyme inhibitors (ACEI) on HF after MI.
Using Brown Norway Katholiek (BNK) rats, which are deficient in kininogen (kinin        precursor) due to a mutation in the kininogen gene, we examined the role of       endogenous kinins in 1) normal cardiac function; 2) myocardial infarction (MI)       caused by coronary artery ligation; 3) cardiac remodeling in the development of        @OBJECT$  (HF)  @PREDICAT$   @SUBJECT$ ; and 4) the cardioprotective effect of       angiotensin-converting enzyme inhibitors (ACEI) on HF after MI.