mononuclear cells
CONCLUSION: The results suggest that ONO-1078 acts       directly on peripheral blood mononuclear cells and that blockade of leukotriene       receptors on blood mononuclear cells by the cysteinyl-leukotriene receptor       antagonist (LTRA) pranlukast (ONO-1078) can dose-dependently inhibit release of       immunoreactive TH2-type cytokines (IL-3, IL-4, GM-CSF, and possibly IL-5), but       not of the TH1-type cytokine IL-2, when stimulated by mite allergen in vitro.
CONCLUSION: The results suggest that ONO-1078 acts       directly on peripheral blood mononuclear cells and that blockade of leukotriene       receptors on  @OBJECT$  @PREDICAT$  @SUBJECT$  by the cysteinyl-leukotriene receptor       antagonist (LTRA) pranlukast (ONO-1078) can dose-dependently inhibit release of       immunoreactive TH2-type cytokines (IL-3, IL-4, GM-CSF, and possibly IL-5), but       not of the TH1-type cytokine IL-2, when stimulated by mite allergen in vitro.