morphological changes
Further research into the nature of the carotid atherosclerotic plaque and the       clustering of systemic factors (infectious, inflammatory and vascular risk       factors) that trigger inflammatory and morphological changes in the asymptomatic        plaque and predispose it to rupture (with subsequent symptomatic thromboembolism)       may yield powerful predictors of stroke which, when combined with the degree of       stenosis and presence of focal neurological symptoms, may improve patient       selection for carotid endarterectomy and its cost effectiveness.
Further research into the nature of the carotid atherosclerotic plaque and the       clustering of systemic factors (infectious, inflammatory and vascular risk       factors) that trigger inflammatory and  @SUBJECT$   @PREDICAT$  the asymptomatic         @OBJECT$  and predispose it to rupture (with subsequent symptomatic thromboembolism)       may yield powerful predictors of stroke which, when combined with the degree of       stenosis and presence of focal neurological symptoms, may improve patient       selection for carotid endarterectomy and its cost effectiveness.