pranlukast
OBJECTIVE: This study was designed to       investigate the protective effect of pranlukast on airway sensitivity to       sulpyrine provocation testing, bronchial responsiveness to methacholine       provocation testing, and to investigate whether this protective activity is       associated with a reduction in aspirin-induced excretion of urinary LTE4 (uLTE4),       a marker of the cysteinyl leukotriene (LT) overproduction that participates in       the pathogenesis of aspirin-induced asthma.
OBJECTIVE: This study was designed to       investigate the protective  @PREDICAT$  of  @SUBJECT$  on airway  @OBJECT$  to       sulpyrine provocation testing, bronchial responsiveness to methacholine       provocation testing, and to investigate whether this protective activity is       associated with a reduction in aspirin-induced excretion of urinary LTE4 (uLTE4),       a marker of the cysteinyl leukotriene (LT) overproduction that participates in       the pathogenesis of aspirin-induced asthma.