catechol-O-methyltransferase inhibitor
Addition of a catechol-O-methyltransferase       inhibitor can increase the duration of levodopa's effect and may prove especially       valuable for patients who experience early wearing off of levodopa.
Addition of a  @SUBJECT$  can increase the duration of  @OBJECT$   @PREDICAT$  and may prove especially       valuable for patients who experience early wearing off of levodopa.