diuretics
Although diuretics have an unparalleled        track record of safety and efficacy, the recent findings suggesting that       long-term use increased the risk for renal cell carcinoma (RCC) is of concern.
Although  @SUBJECT$  have an unparalleled        track record of safety and efficacy, the recent findings suggesting that       long-term use increased the  @PREDICAT$  for  @OBJECT$  (RCC) is of concern.