SERMs
Future drug       development efforts should focus on developing superior SERMs that have a greater       efficacy against ER-positive tumors and do not cause hot flashes or       thromboembolism, and explore combination strategies to simultaneously target       hormone-dependent as well as hormone-independent breast cancer.
Future drug       development efforts should focus on developing superior  @SUBJECT$  that have a greater       efficacy against ER-positive tumors and do not  @PREDICAT$  hot flashes or        @OBJECT$ , and explore combination strategies to simultaneously target       hormone-dependent as well as hormone-independent breast cancer.