IL-1Ra
METHODS: Rats with developing adjuvant arthritis or established collagen-induced        arthritis were treated with IL-1Ra by continuous infusion in order to determine       and maintain efficacious blood levels of this IL-1 inhibitory protein in the rats       for comparison with human clinical data.
METHODS: Rats with developing  @OBJECT$  or established collagen-induced        arthritis were  @PREDICAT$  with  @SUBJECT$  by continuous infusion in order to determine       and maintain efficacious blood levels of this IL-1 inhibitory protein in the rats       for comparison with human clinical data.