streptokinase
BACKGROUND: A major limitation of streptokinase is the development and       persistence of problematic neutralizing antibodies that have the potential to       limit the effectiveness of repeat streptokinase therapy.
BACKGROUND: A major limitation of streptokinase is the development and       persistence of problematic neutralizing antibodies that have the potential to       limit the effectiveness of repeat  @OBJECT$  @SUBJECT$  @PREDICAT$ .