combination therapy
The potentially complementary mechanisms       of action of these two effective DMARDs should provide a rationale for their use        in combination therapy for patients whose condition no longer responds to       methotrexate alone.
The potentially complementary mechanisms       of action of these two effective DMARDs should provide a rationale for their use        in  @SUBJECT$   @PREDICAT$   @OBJECT$  whose condition no longer responds to       methotrexate alone.