beta-blockers
CONCLUSION: The effect of beta-adrenergic       antagonists on ET-1 production of the endothelium may at least partially explain        the efficacy of beta-blockers in the treatment of diseases such as advanced heart       failure, essential hypertension as well as acute coronary syndromes.
CONCLUSION: The effect of beta-adrenergic       antagonists on ET-1 production of the endothelium may at least partially explain        the efficacy of  @SUBJECT$  in the treatment of  @PREDICAT$  @OBJECT$ , essential hypertension as well as acute coronary syndromes.