heart failure
BACKGROUND: Patients with end-stage heart failure are often refractory to maximal       oral therapy, and they have high mortality rates, poor quality of life, and       frequent hospitalizations with elevated health care costs.
BACKGROUND:  @OBJECT$   @PREDICAT$  end-stage  @SUBJECT$  are often refractory to maximal       oral therapy, and they have high mortality rates, poor quality of life, and       frequent hospitalizations with elevated health care costs.