amenorrhea
The change of estrogen function, represented by amenorrhea or hot flashes, that       results from breast cancer treatment may increase the risk of major depressive       disorder in those women undergoing treatment for breast cancer.
The change of estrogen function, represented by  @SUBJECT$  or hot flashes, that       results from breast cancer treatment may increase the  @PREDICAT$  of  @OBJECT$  in those women undergoing treatment for breast cancer.