Hurricane Katrina
There will be a delay in future Shuttle flights until at least the fall of 2006, due to damaged NASA facilities that house and manufacture parts for the Shuttle program. 
 has damaged several NASA facilities, including not only the Kennedy Space Center, but more importantly the Michoud Assembly Facility in New Orleans itself and the Stennis Space Center on the gulf coast of Mississippi, both major worksites of NASA subcontractors that help with the servicing of parts for the shuttle. 
NASA announces Shuttle delay due to Hurricane Katrina